Search of human proteins with 16418351

Search of human proteins with 16418351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16418351 coiled-coil domain containing 97 [Homo sapiens]
         (343 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16418351 coiled-coil domain containing 97 [Homo sapiens]           699   0.0  
gi|118600967 shroom family member 4 [Homo sapiens]                     47   2e-05
gi|171460958 nucleolar protein 10 [Homo sapiens]                       47   3e-05
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    45   7e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    45   9e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          45   1e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   45   1e-04
gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]                    44   2e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               44   2e-04
gi|221219020 NYD-SP11 protein [Homo sapiens]                           44   3e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    44   3e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    41   0.001
gi|45331217 zinc finger protein 526 [Homo sapiens]                     41   0.001
gi|31543091 MAK16 homolog [Homo sapiens]                               41   0.002
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              40   0.002
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         40   0.002
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    40   0.003
gi|21361639 DIPB protein [Homo sapiens]                                40   0.003
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        40   0.003
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    40   0.004
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    40   0.004
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    40   0.004
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    40   0.004
gi|55741677 SET domain containing 1A [Homo sapiens]                    39   0.005
gi|148746195 trichohyalin [Homo sapiens]                               39   0.005
gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]    39   0.005
gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]    39   0.005
gi|55956788 nucleolin [Homo sapiens]                                   39   0.009
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ...    39   0.009
gi|31543392 peroxisome proliferator-activated receptor gamma, co...    39   0.009

>gi|16418351 coiled-coil domain containing 97 [Homo sapiens]
          Length = 343

 Score =  699 bits (1805), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MEAVATATAAKEPDKGCIEPGPGHWGELSRTPVPSKPQDKVEAAEATPVALDSDTSGAEN 60
           MEAVATATAAKEPDKGCIEPGPGHWGELSRTPVPSKPQDKVEAAEATPVALDSDTSGAEN
Sbjct: 1   MEAVATATAAKEPDKGCIEPGPGHWGELSRTPVPSKPQDKVEAAEATPVALDSDTSGAEN 60

Query: 61  AAVSAMLHAVAASRLPVCSQQQGEPDLTEHEKVAILAQLYHEKPLVFLERFRTGLREEHL 120
           AAVSAMLHAVAASRLPVCSQQQGEPDLTEHEKVAILAQLYHEKPLVFLERFRTGLREEHL
Sbjct: 61  AAVSAMLHAVAASRLPVCSQQQGEPDLTEHEKVAILAQLYHEKPLVFLERFRTGLREEHL 120

Query: 121 ACFGHVRGDHRADFYCAEVARQGTARPRTLRTRLRNRRYAALRELIQGGEYFSDEQMRFR 180
           ACFGHVRGDHRADFYCAEVARQGTARPRTLRTRLRNRRYAALRELIQGGEYFSDEQMRFR
Sbjct: 121 ACFGHVRGDHRADFYCAEVARQGTARPRTLRTRLRNRRYAALRELIQGGEYFSDEQMRFR 180

Query: 181 APLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQ 240
           APLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQ
Sbjct: 181 APLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQ 240

Query: 241 QEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGD 300
           QEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGD
Sbjct: 241 QEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGD 300

Query: 301 FDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD 343
           FDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD
Sbjct: 301 FDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD 343


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 7/84 (8%)

Query: 190  GQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLE 249
            G     + L AR     PP+P  P          L ++ ++++ QQ+  +QQEEEE   E
Sbjct: 1084 GDETQSDLLGARKKAFPPPRPPPPNWE----KYRLFRAAQQQKQQQQQQKQQEEEE---E 1136

Query: 250  EEEEEEDSDEEDQRSGKDSEAWVP 273
            EEEEEE+ +EE++   ++ E  +P
Sbjct: 1137 EEEEEEEEEEEEEEEAEEEEEELP 1160


>gi|171460958 nucleolar protein 10 [Homo sapiens]
          Length = 688

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 220 LSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPD--SEE 277
           L+ L+ +  E+R+ + RLL+QQE  E   EEE E + SD E   S  D +AWV +   + 
Sbjct: 506 LNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR 565

Query: 278 RLILREEFTSRMHQ 291
           RL+ +EE   R  +
Sbjct: 566 RLLQQEEKVKRQER 579


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 6/119 (5%)

Query: 229 EERELQQRLLQQQEEEEACLE-----EEEEEEDSDEEDQRSGKDSEAWVPDSEERLILRE 283
           + R++ ++ L+ QE  +A LE     EEEEEE   EE +  G D E     S E+    +
Sbjct: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411

Query: 284 EFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERY-FDEEEPEDAPSPELD 341
           E +    +R    +D   D S   ++   ++    ARD+EE +  D +  +DA S + D
Sbjct: 412 EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 44/155 (28%), Positives = 61/155 (39%), Gaps = 34/155 (21%)

Query: 196 EELSART---PTHQPPKPGSPGRPACPLSNLLLQSYE--------ERELQQRLLQQQEEE 244
           EEL A     P   PP P  PG    P   L+ +           E +L    +   +EE
Sbjct: 830 EELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEE 889

Query: 245 EACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYS 304
           E   EEEEEEE+ +EE++   +D E    D EE     EE      + F + ++G+    
Sbjct: 890 E---EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF-EEEEGEL--- 942

Query: 305 TVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPE 339
                           +EEE   DEEE E+    E
Sbjct: 943 ----------------EEEEEEEDEEEEEELEEVE 961



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 19/45 (42%), Positives = 26/45 (57%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVP 273
           EE E ++  L+++EEEE   EEEE EE  D E   +G + E   P
Sbjct: 933 EEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAP 977


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 12/117 (10%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDG-- 296
           + +E+EE   EEEEE E+ DE+D   G+D E    + EE     EE  +  HQ       
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTR 179

Query: 297 --KDGDFDYSTVDDNPDFD--------NLDIVARDEEERYFDEEEPEDAPSPELDGD 343
             +D + D +  D+  ++D        NL  +A D   R   E E     S  L+ D
Sbjct: 180 IMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDD 236



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 29/136 (21%)

Query: 201 RTPTHQPPKPGSPGRP-ACPLSNLLLQSYEERELQQRLLQQQEEE-EACLEEEEEEEDSD 258
           +T   QP +P    +P A    +  +   ++ +  + + +++E+E E   E+ +E  D D
Sbjct: 62  KTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121

Query: 259 EEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIV 318
           EED+   ++ E  + + +E                    D D D   V+D  +       
Sbjct: 122 EEDEEGDREEEEEIEEEDE--------------------DDDEDGEDVEDEEE------- 154

Query: 319 ARDEEERYFDEEEPED 334
             +EEE   +EEE ED
Sbjct: 155 EEEEEEEEEEEEENED 170


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 48/154 (31%), Positives = 70/154 (45%), Gaps = 32/154 (20%)

Query: 207  PPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQE----EEEACLEEEEEEEDSDEEDQ 262
            P   G   RPA PL    L S  E + ++ L ++QE    EEEA  EEEEE++D D+ D 
Sbjct: 1014 PKGVGVRRRPARPLE---LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDD 1070

Query: 263  RSGKD-----------SEAWVPDSEER-----LILREEFTSRMHQRFLDGKDGDFDYSTV 306
            R   +           SE    DS+E      +  + E TS         +  +F+ S+ 
Sbjct: 1071 RDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSE----SSESSEFESSSE 1126

Query: 307  DD-NPDFDNLDIVARDEEERYFDEEEPEDAPSPE 339
               +   D  ++VAR+EEE    EEE E+  + E
Sbjct: 1127 SSPSSSEDEEEVVAREEEE----EEEEEEMVAEE 1156


>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
          Length = 1507

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)

Query: 234  QQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRF 293
            +QRL + ++EEE   EEE+EEED DE+D  +    E    D+++ L    E         
Sbjct: 1391 RQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDEL---DTDQLLEAELEEDDNNENA- 1446

Query: 294  LDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
              G+DGD D+S  D+  +  NL     D E+   D +E
Sbjct: 1447 --GEDGDNDFSPSDE--ELANLLEEGEDGEDEDSDADE 1480


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 9/111 (8%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE--FT 286
           EE E ++   +++EEEE   EEEEEEE+ +EE++   ++ E   PD    +I +E+   T
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD----VIFQEDTSHT 320

Query: 287 SRMHQRFLDGKDGDF---DYSTVDDNPDFDNLDIVARDEEERYFDEEEPED 334
           S      L G +      +YS + +    D+ D      +    DE E +D
Sbjct: 321 SAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD 371



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 218 CPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           CP S L   + EE   Q+ +L  +EE+E   EEEEEEE+ +EE++   ++ E    + EE
Sbjct: 236 CPQS-LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294

Query: 278 RLILREE 284
                EE
Sbjct: 295 EEEEEEE 301



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 8/107 (7%)

Query: 238 LQQQEEEEACLEEEE-----EEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQR 292
           L Q+  E A  EE E     + ED++E  + + + S+   P S E     E   S   + 
Sbjct: 197 LLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEE---SSKQKG 253

Query: 293 FLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPE 339
            L  ++ D +    ++  + D  +    +EEE   +EEE E+    E
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 11/115 (9%)

Query: 229  EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
            +E E Q+ L  ++EEE    EE EEEE  +EE++R  ++      + EE+ + +EE   +
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE------EGEEKQVEKEEEEKK 2288

Query: 289  MHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD 343
              ++    ++        ++       +I++ +E E   DEEE E++ S E + D
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKE-----EIMSEEETESLSDEEEEEESCSLEEEVD 2338



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 252  EEEEDSDEEDQRSGKDSEAWVPDSEERLILREE---FTSRMHQRFLDGKDGDFDYSTVDD 308
            +EE+ ++EE + + K SE  + D EE  I  EE   F  R  ++  + K GD        
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215

Query: 309  NPDFDNLDIVARDEEERYFDEEEPEDAPSPE 339
              D    +    +E E   DE E +++ S E
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSE 2246



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 1/64 (1%)

Query: 229  EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
            +++E  Q   +  EE+E  + EEE E  SDEE++      E  V D E+ ++ +E+    
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV-DREKEILKKEKQFKL 2352

Query: 289  MHQR 292
              QR
Sbjct: 2353 QEQR 2356



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 229  EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
            E +++ + +L  + +E+    ++EEE   +EE  R G++ E  V + E+R I  E   +R
Sbjct: 1520 EWKQVWENMLSSKSKEQQY--KDEEEVTLEEEVSREGEEKEQQVTE-EQRHIQEEHKWAR 1576

Query: 289  MHQR 292
            +H++
Sbjct: 1577 IHRK 1580



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 10/81 (12%)

Query: 227  SYEERELQQRLLQQQEEEEACLEEEE----EEEDSDEEDQRSGKDSEAWVPDSE------ 276
            S++E EL Q   +  EE++   EEEE    + E   EE+ +  ++ E  + + E      
Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788

Query: 277  ERLILREEFTSRMHQRFLDGK 297
            E++   EE   R  ++ ++ K
Sbjct: 1789 EKMPEEEERLGRKREQLIEKK 1809


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 195  QEELSARTPTHQPPKP---------GSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEE 245
            QE LS R  + Q P               RP       LL+  +E   ++   + +EEEE
Sbjct: 1023 QEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEE 1082

Query: 246  ACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGK-------- 297
               EEEEEEED +EE++   ++ E  +  S  RL   +    +  + F+  K        
Sbjct: 1083 ---EEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRR 1139

Query: 298  -DGDFDYSTVDD-----NPDFDNLDIVARDEEERYFDEEEPEDAPSPELDG 342
             +      T+ +     N  FDN D      EER   + EP      E DG
Sbjct: 1140 INSSVTTETISETTEVLNEPFDNSD------EERPMPQLEPTCEIEVEEDG 1184



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 33/167 (19%)

Query: 181  APLLYEQYI---GQYLTQEELSARTPTHQPPKPG-SPGRPACPLSNLLLQSYEERELQQR 236
            +P+  E+ +   G+ L  +E + R  T  P  P  SPG                   +  
Sbjct: 1303 SPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKP----------------EDD 1346

Query: 237  LLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSE-----AWVPDSEERLILREEFTSRMHQ 291
            L++ +EEEE   EEEEEEE+ + E++  G + E     A   + EE  I  E+  S    
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDS---- 1402

Query: 292  RFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSP 338
                 +  D +    +D     N D  A DE++ + +  E E    P
Sbjct: 1403 ----ARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELP 1445



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 227  SYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE-- 284
            S EERE ++   ++  E+ +C E+EE+E  S   + R    S A V    + L   E   
Sbjct: 998  SEEEREAEKEA-ERLMEQASCWEKEEQEILSTRANSR---QSPAKVQSKNKYLHSPESRP 1053

Query: 285  FTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPED 334
             T    Q     K+   +    +D  + +  +    DEEE   +EEE E+
Sbjct: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 252  EEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKD----GDFDYSTVD 307
            EEE ++++E +R  + +  W  + EE+ IL     SR     +  K+             
Sbjct: 999  EEEREAEKEAERLMEQASCW--EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056

Query: 308  DNPDFDNLDIVARDEEERYFDEEEPEDAPSPELD 341
            +      L   + +EEE   DEEE E+    E D
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEED 1090



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%)

Query: 230  ERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRM 289
            E+E   RL   +EEEE    E+EE   +++ D     DS     + E+  + RE F   +
Sbjct: 1398 EKEDSARLDDHEEEEE----EDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVL 1453

Query: 290  --HQRFLD 295
               + FLD
Sbjct: 1454 ENQETFLD 1461


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 11/104 (10%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEF 285
           +  E  ++   + +  EEEE   EEEEE+E+S+EE++  G+   +   + +E++   ++ 
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575

Query: 286 TSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDE 329
              + ++       D +Y + DD           R +EER +D+
Sbjct: 576 GKTLDKKPSKEMSSDSEYDSDDD-----------RTKEERAYDK 608



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 31/162 (19%), Positives = 69/162 (42%), Gaps = 11/162 (6%)

Query: 190 GQYLTQEELSARTPTH------QPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEE 243
           G+ LT+ +  AR          Q      P + + P    + +  + +++ Q+L  ++  
Sbjct: 405 GKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVS 464

Query: 244 E--EACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDF 301
           E  E C   E  E+   E+++           D+E+  +  +++ +       +  +G+ 
Sbjct: 465 ESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL--DDWEAMASDEETEKVEGNK 522

Query: 302 DYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD 343
            +  V +NP+ +  +    +EE+   +EEE E+  S   +GD
Sbjct: 523 VHIEVKENPEEEEEE-EEEEEEDEESEEEEEEEGESEGSEGD 563


>gi|45331217 zinc finger protein 526 [Homo sapiens]
          Length = 670

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 200 ARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQ------QRLLQQQ--------EEEE 245
           A  P   P  P +P  P  P S + ++ YE  E        +  L+ Q        +EE 
Sbjct: 169 AEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEER 228

Query: 246 ACLEEEEEEEDSDEEDQRSGKDSEA 270
             LEEEEE+++ DEED    +D EA
Sbjct: 229 NGLEEEEEDDEEDEEDDEEMEDEEA 253


>gi|31543091 MAK16 homolog [Homo sapiens]
          Length = 300

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 59/245 (24%), Positives = 98/245 (40%), Gaps = 47/245 (19%)

Query: 115 LREEHLACFGHVRGDHRADFYCAEVARQGTARPRTLRTRLR-NRRYAALRELIQGGEYFS 173
           ++EE   C+ +++   RA F            PR L  R+R ++ Y    E I     + 
Sbjct: 54  IKEEKGQCYLYMKVIERAAF------------PRRLWERVRLSKNYEKALEQIDENLIYW 101

Query: 174 DEQMRFRAPLLYEQYIGQYL------TQEELSARTPTHQPPKPGSPGRPACPLSNLLLQS 227
              +R +    + + I QYL      T +      P  +  +     R    L    L +
Sbjct: 102 PRFIRHKCKQRFTK-ITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDN 160

Query: 228 YEERELQQRLLQQQEEE---------EACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEER 278
             E+EL +RL Q    +         +  LE++E E DS + ++   KD +    D +E 
Sbjct: 161 AIEKELLERLKQDTYGDIYNFPIHAFDKALEQQEAESDSSDTEE---KDDD----DDDEE 213

Query: 279 LILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVA-RDEEERYFDEEEPEDAPS 337
            + + EF           +DG+ D S + D  D D LD  +  D++ +   EEE E A S
Sbjct: 214 DVGKREFV----------EDGEVDESDISDFEDMDKLDASSDEDQDGKSSSEEEEEKALS 263

Query: 338 PELDG 342
            +  G
Sbjct: 264 AKHKG 268


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 6/83 (7%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
           +++E ++ L +++EEEE   EEEE EE+ +E ++   +  E  +   E+ L   E F+  
Sbjct: 17  DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76

Query: 289 MHQRFLDGKDGDFDYSTVDDNPD 311
              +  D   GD+D    DD PD
Sbjct: 77  YLWKVTD--IGDYD----DDFPD 93



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 5/71 (7%)

Query: 211 GSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEA 270
           G PG+     S   L+  EE E  +   ++ EEEE   EE EEEE+   E++  G++ E 
Sbjct: 11  GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEE---EEVEEEEEEVVEEELVGEEQEL 67

Query: 271 WVPD--SEERL 279
             P+  SEE L
Sbjct: 68  EAPETFSEEYL 78



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 1/45 (2%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILRE 283
           + Q+E E  LEEEEEEE+ +EE++   ++ E  V + EE ++  E
Sbjct: 16  KDQKESEEELEEEEEEEEVEEEEEEVEEEEEE-VEEEEEEVVEEE 59


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 14/150 (9%)

Query: 200 ARTPTHQPPKPGSPGRP-ACPLSNLLLQSYEERELQQ---RLLQQQEEEEACLEEEEEEE 255
           A +P   P  P    +P      ++L  S  +++L     R    ++EE A     +EEE
Sbjct: 4   AESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEE 63

Query: 256 D--SDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFD 313
           D  SDEED+ S   S+    DSE   + R   +S   +   +G +G+ D ++  D  D  
Sbjct: 64  DNHSDEEDRASEPKSQD--QDSEVNELSRGPTSSPCEE---EGDEGEEDRTS--DLRDEA 116

Query: 314 NLDIVARDEEERYFDEEEPEDAPSPELDGD 343
           +      DE E  +DEE PE+ P+P +  D
Sbjct: 117 SSVTRELDEHELDYDEEVPEE-PAPAVQED 145



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 231 RELQQRLLQQQEE--EEAC--LEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFT 286
           REL +  L   EE  EE    ++E+E E+   E+D+  G+ +      +  + +  +E  
Sbjct: 121 RELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESL 180

Query: 287 SRMHQRFLDGKDGDFDYSTVDDN 309
               ++  +  DG+ D   +DD+
Sbjct: 181 EAAKEKKKEDDDGEIDDGEIDDD 203


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 10/112 (8%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDE----------EDQRSGKDSEAWVPDSEER 278
           E++EL+++  Q QE+EE   E+EE+  + +E          E ++  ++ E  + D EER
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398

Query: 279 LILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEE 330
           +  ++E      +R  + +        + +       +   RD+EE+  +EE
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 5/103 (4%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
           EE  +++R  + +EEEE   E+EE+ ++ +E+ Q   ++ E W  + EE++  +EE    
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQE--QEEEMW--EQEEKMWEQEE-KMW 765

Query: 289 MHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
             QR  + K+  +++  + +       +   RD+EE+   +EE
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE 808



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 24/111 (21%), Positives = 58/111 (52%), Gaps = 19/111 (17%)

Query: 229 EERELQQRLLQQQEE---EEACLEEEEE-----EEDSDEEDQRSGKDSEAWVPDSEERLI 280
           EE+E QQ+ L +Q+E   E+  ++E+EE     EE   ++++  G++ + W    +E++ 
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW---RQEKMR 540

Query: 281 LREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
            +E+      ++  D +   +D          + ++   +++E++ +D+EE
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQE--------ERMEKKTQEQEKKTWDQEE 583



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 16/100 (16%)

Query: 234 QQRLLQQQEEEEACLEEE--EEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQ 291
           Q++ L++QE+E    E+E  E++E  ++E+Q   ++ + W  + EE++  +EE   R  +
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW--EQEEKMREQEEKMWRQEE 376

Query: 292 RFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
           R              +        +   RD+EER ++++E
Sbjct: 377 RLW------------EQEKQMREQEQKMRDQEERMWEQDE 404



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 17/56 (30%), Positives = 35/56 (62%), Gaps = 4/56 (7%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE 284
           EE  +++R  + +EEEE   E+EE+ ++ +E+ Q   ++ + W  + EE++  +EE
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQE--QEEKMW--EQEEKMQEQEE 638



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 14/55 (25%), Positives = 34/55 (61%)

Query: 230 ERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE 284
           E+  +++ +Q+QE++    EE+ +EE+   E ++  ++ E  + + EE++  +EE
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 22/104 (21%), Positives = 54/104 (51%), Gaps = 6/104 (5%)

Query: 228 YEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTS 287
           + + +++++  Q  E+EE   ++E++  D +E  ++  ++ E    D EE+  +REE   
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK--MREE--E 589

Query: 288 RMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
           RM +R  + K  + +    +        +   +++EE+ +++EE
Sbjct: 590 RMRER--EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE 631



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 15/126 (11%)

Query: 229 EERELQQRLLQQQEEEEACLEEEE----------EEEDSDEEDQRSGKDSE-AW----VP 273
           EE  +++R  + +EEEE   E+EE          E+E+ + + QR  +  E  W    + 
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507

Query: 274 DSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPE 333
           + EE++  +EE      + +   K         +        +   RD+E++ +D+EE  
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567

Query: 334 DAPSPE 339
           +  + E
Sbjct: 568 EKKTQE 573



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 24/127 (18%), Positives = 58/127 (45%), Gaps = 24/127 (18%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDE-----EDQRSGKDSEAW----VPDSEERL 279
           +E ++Q++  + QE+EE   E+EE+ ++ +E     E++   ++ + W    +P+ +E+L
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667

Query: 280 ILREEF---------------TSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEE 324
              E+                  +M ++  + +   +D   + +       +   R+EEE
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727

Query: 325 RYFDEEE 331
              ++EE
Sbjct: 728 MMREQEE 734



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 16/63 (25%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 225 LQSYEERELQQRLLQ---QQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLIL 281
           +Q  EE+  +Q  ++   Q++E++   +E+  EE+S  E ++  ++ E  + + EE++  
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738

Query: 282 REE 284
           +EE
Sbjct: 739 QEE 741



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 13/106 (12%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEF 285
           Q  E RE ++ L +Q+E  E   + +E+EE   E++++  ++ E  +   EERL  +E+ 
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQ 384

Query: 286 TSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
                Q+  D ++  ++             D   R++EER  ++E+
Sbjct: 385 MREQEQKMRDQEERMWEQ------------DERLREKEERMREQEK 418



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 21/113 (18%), Positives = 56/113 (49%), Gaps = 6/113 (5%)

Query: 225 LQSYEERELQQRLLQQQ----EEEEACLEEEEEEEDSDE--EDQRSGKDSEAWVPDSEER 278
           L+  EER  +Q  + +Q     EE+   E+E++  D +E  +++   ++ E  + + EE 
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465

Query: 279 LILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
           +  +EE   +  +   + ++ ++    + +  +        +++EE+ +++EE
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 23/108 (21%), Positives = 55/108 (50%), Gaps = 5/108 (4%)

Query: 226 QSYEERELQQRLLQQQEE--EEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILRE 283
           Q  + RE ++++ +Q+E   E+     E+E++  D+E++   +D    + + EER+  +E
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER--LREKEERMREQE 417

Query: 284 EFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
           +   ++ +   + K  + +  T D        + + R+ E++  +EEE
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI-REREKKMREEEE 464



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 21/103 (20%), Positives = 56/103 (54%), Gaps = 13/103 (12%)

Query: 234 QQRLLQQQEEEEACLEE---EEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMH 290
           ++ ++++QEE+    EE   E+EE+  ++E++   ++ + W  + EE++  +EE      
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW--EQEEKMWEQEE-KMWEQ 657

Query: 291 QRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPE 333
           QR  + K+  +++  + +           +++EE+ +++E+ E
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKM-------QEQEEKIWEQEKME 693


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 3/52 (5%)

Query: 229 EERELQQRLLQQQEEEEACLEEEE---EEEDSDEEDQRSGKDSEAWVPDSEE 277
           +ERE++    ++ E EE    EEE   EEE  DE D+ S +DSE  + D +E
Sbjct: 87  QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 3/52 (5%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           +S EE E ++   + + EEE+  E +EE E+  EE+    ++SEA   + EE
Sbjct: 100 ESEEESESEE---ESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEE 148


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 20/55 (36%), Positives = 34/55 (61%)

Query: 216 PACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEA 270
           P  PL+ +  Q+  + E ++    ++EEEE   EEEEEEE+ +EE++   ++ EA
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 21/55 (38%), Positives = 32/55 (58%)

Query: 210 PGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRS 264
           P  P  P  P +N   +  EE E ++   + +EEEE   EEEEEEE+ +EE++ +
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 16/38 (42%), Positives = 25/38 (65%)

Query: 240 QQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           ++EEEE   +EEEEEED +EE++   ++ E    + EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           +++EEEE   EEEEE+E+ +EE++   ++ E    + EE
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 15/39 (38%), Positives = 26/39 (66%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           +++EEEE   EEEEEE++ +EE++   ++ E    + EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 242 EEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE 284
           +EEE   EEEEE+E+ +EED+   ++ E    + EE     EE
Sbjct: 732 KEEE---EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 18/37 (48%), Positives = 27/37 (72%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSG 265
           E+ E+Q+   +++EEEE   EEEEEEE+ +EE  R+G
Sbjct: 116 EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAG 152



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 15/33 (45%), Positives = 23/33 (69%)

Query: 230 ERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQ 262
           ERE +   +Q++  EE   EEEEEEE+ +EE++
Sbjct: 112 EREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEE 144



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 14/40 (35%), Positives = 25/40 (62%)

Query: 230 ERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSE 269
           E E ++    ++ +EE   EEEEEEE+ +EE++   ++ E
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTS 287
           +++EEEE   EEEEEEE      Q SG + E +  + ++ L   EE+ S
Sbjct: 131 EEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQAL---EEWVS 176



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 249 EEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFD-YSTVD 307
           EEE E E+ DEE Q  G + E    + EE     EE      +    G  G+ + YS  +
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167

Query: 308 D 308
           D
Sbjct: 168 D 168



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 3/38 (7%)

Query: 239 QQQEEEEACLEE---EEEEEDSDEEDQRSGKDSEAWVP 273
           +++EE+E   EE   EEEEE+ +EE++   ++ E   P
Sbjct: 112 EREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQP 149


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/31 (54%), Positives = 24/31 (77%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSE 269
           +++EEEE   EEEEEEE+ +EED+ SG  S+
Sbjct: 302 EEEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 224 LLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSG-----KDSEAWVPDS 275
           L +   E E ++   +++EEEE   EEEEE+E+S  +  RSG     K  + W  DS
Sbjct: 294 LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350



 Score = 35.8 bits (81), Expect = 0.057
 Identities = 19/44 (43%), Positives = 27/44 (61%), Gaps = 3/44 (6%)

Query: 227 SYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEA 270
           S  E E     L ++EEEE   EEEEEEE+ +EE++   +D E+
Sbjct: 287 SKSEVEALTEQLSEEEEEE---EEEEEEEEEEEEEEEEEEDEES 327



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 228 YEERELQQRLLQQQEEEEACLEE---EEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           Y+   + +R+    + E   L E   EEEEE+ +EE++   ++ E    + EE
Sbjct: 274 YDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/31 (54%), Positives = 24/31 (77%)

Query: 239 QQQEEEEACLEEEEEEEDSDEEDQRSGKDSE 269
           +++EEEE   EEEEEEE+ +EED+ SG  S+
Sbjct: 302 EEEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 224 LLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSG-----KDSEAWVPDS 275
           L +   E E ++   +++EEEE   EEEEE+E+S  +  RSG     K  + W  DS
Sbjct: 294 LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350



 Score = 35.8 bits (81), Expect = 0.057
 Identities = 19/44 (43%), Positives = 27/44 (61%), Gaps = 3/44 (6%)

Query: 227 SYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEA 270
           S  E E     L ++EEEE   EEEEEEE+ +EE++   +D E+
Sbjct: 287 SKSEVEALTEQLSEEEEEE---EEEEEEEEEEEEEEEEEEDEES 327



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 228 YEERELQQRLLQQQEEEEACLEE---EEEEEDSDEEDQRSGKDSEAWVPDSEE 277
           Y+   + +R+    + E   L E   EEEEE+ +EE++   ++ E    + EE
Sbjct: 274 YDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 23/73 (31%), Positives = 34/73 (46%)

Query: 207  PPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGK 266
            PP   +PG      +         +E ++  L+  EEE    E+E+++ED D+ED     
Sbjct: 1651 PPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDD 1710

Query: 267  DSEAWVPDSEERL 279
            D E    DSEE L
Sbjct: 1711 DDEDLRTDSEESL 1723



 Score = 35.8 bits (81), Expect = 0.057
 Identities = 17/68 (25%), Positives = 36/68 (52%)

Query: 208  PKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKD 267
            P+ G+    A    +      EE EL +   +  E+E+   ++++E++D D++D+    D
Sbjct: 1659 PREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTD 1718

Query: 268  SEAWVPDS 275
            SE  +P++
Sbjct: 1719 SEESLPEA 1726


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 9/105 (8%)

Query: 173  SDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKP--------GSPGRPACPLSNLL 224
            SDE  R R  L +      Y    + +   P  +PP+P         SP         ++
Sbjct: 1283 SDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVV 1342

Query: 225  LQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSE 269
            +   EE + QQ L QQ+EE E   EEE EEE+ +  D  S  D E
Sbjct: 1343 VAEAEEPKPQQ-LQQQREEGEEEGEEEGEEEEEESSDSSSSSDGE 1386



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 26/117 (22%)

Query: 206  QPPKPGSPGRPACP---------------LSNLLLQSYEERELQQRLLQQQEEEEACLEE 250
            Q  + G PGRP                    +  L S  E   Q+   ++ EE++     
Sbjct: 927  QEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDD----- 981

Query: 251  EEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVD 307
            EE+EED D E+       E  V D E+     EE  S          DG+ D ST D
Sbjct: 982  EEDEEDEDREEAVDTTKKETEVSDGED-----EESDSSSKCSLYADSDGEND-STSD 1032



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 201 RTPTHQPPKPGSPGR---PACPLSNLLLQSYEERELQQR---LLQQQEEEEACLEEEEEE 254
           R      P+P SP R   PA   +N  +   +   L  R   LL++Q  + + L  + EE
Sbjct: 453 REEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEE 512

Query: 255 EDSDEEDQRSGKDSEAWVP 273
           E+ +       +D+ + VP
Sbjct: 513 EEENSSMVLGARDTGSEVP 531


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/188 (25%), Positives = 73/188 (38%), Gaps = 24/188 (12%)

Query: 147  PRTLRTRLRNRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQ 206
            P   R + R ++Y    EL Q  E    E+   R    +E+   QY  ++EL        
Sbjct: 978  PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER---QYRKKDELQQEE---- 1030

Query: 207  PPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEE---EEEDSDEEDQR 263
                            LL +  E+R LQ+R  Q +EEEE   EEE+   EE ++    + 
Sbjct: 1031 --------------EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076

Query: 264  SGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEE 323
              +  +      EE  +LREE   R  Q        + +    ++    +  +   R E 
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136

Query: 324  ERYFDEEE 331
            ER + EEE
Sbjct: 1137 ERQYREEE 1144



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 19/181 (10%)

Query: 151  RTRLRNRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKP 210
            R + R R+Y    EL Q  E    E+   R     E+   QY  +EEL          +P
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELER---QYRKEEELQQEEEQLLREEP 1098

Query: 211  GSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEA 270
                R             +ERE Q R  ++ ++EE  L  EE E+   +E +R  ++ E 
Sbjct: 1099 EKRRR-------------QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145

Query: 271  WVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEE 330
                 EE  +LREE   R  Q  L+ +  + +    ++           R E ER + EE
Sbjct: 1146 --VQQEEEQLLREEPEKRRRQE-LERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202

Query: 331  E 331
            E
Sbjct: 1203 E 1203



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 43/172 (25%), Positives = 70/172 (40%), Gaps = 18/172 (10%)

Query: 175  EQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQ 234
            EQ+R    LL E+   + L +EE   R    Q  +     +       LL +  E+R  Q
Sbjct: 897  EQLRKEQQLLQEEE--EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954

Query: 235  QRLLQQ------QEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
            +R  Q       Q++EE  L EE E+    E +++  ++ E      EE  +LREE   R
Sbjct: 955  ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL---QQEEEQLLREEREKR 1011

Query: 289  MHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPEL 340
              Q +      +  Y   D+    +   ++  + E+R   E E +     EL
Sbjct: 1012 RRQEW------ERQYRKKDELQQ-EEEQLLREEREKRRLQERERQYREEEEL 1056



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 9/109 (8%)

Query: 225  LQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE 284
            L+  E++E ++R  + QEE++  L EE EE+   +E  R  ++ E  + + EE+ + R+E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQL-LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357

Query: 285  FTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPE 333
               +  +  L  ++    +   +          + R E ER F +EE +
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQR--------LRRQERERKFLKEEQQ 1398



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 13/108 (12%)

Query: 195 QEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEE-- 252
           ++ LSAR P  +  +               L   EE+E ++R  +++E+E   LEEEE  
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840

Query: 253 ----------EEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMH 290
                     EEED  +EDQ   +  E    D + R  L EE   R H
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQ-RRDQKWRWQLEEERKRRRH 887



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 8/71 (11%)

Query: 226 QSYEERELQQRLLQQQEEEE----ACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLIL 281
           + +E+   +Q+L + QEEE       LEEEE  E  +  +Q+  ++ E    +  E+ + 
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE----ERREQRLK 520

Query: 282 REEFTSRMHQR 292
           R+E   R+ QR
Sbjct: 521 RQEEEERLQQR 531



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 229 EERELQQRLLQQQEEEEACLEEEE---EEEDSDEEDQRSGKDSEAWVPDSEERLILREEF 285
           EE   +QR LQ++EE+   LE +E   E ++ +++ QR  ++ +      EER   +EE 
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321

Query: 286 TSRMHQR 292
             +  +R
Sbjct: 322 REQQERR 328



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 5/68 (7%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEE--DQRSGKDSEAWVPDSEERLILRE 283
           Q +E+   +QRL ++QEE    L+ EEE E  ++E   Q+  +D E    +  ER +  E
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE---EERRERWLKLE 492

Query: 284 EFTSRMHQ 291
           E   R  Q
Sbjct: 493 EEERREQQ 500



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 174 DEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEEREL 233
           +E+ + R     E+ + Q L +EE+       +  +      P       LL+S E+ E 
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642

Query: 234 QQRLL--QQQEEEEACLEEEEEEEDSD-------EEDQRSGKDSEAWVPDSEERL 279
           +Q+ L  +QQE  E  L+ EEEEE  +       EE++R  + +E     + ER+
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 9/75 (12%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEE--------DSDEEDQRSGKDSEAWVPDSEER-L 279
           E+R  ++  LQ QEEE A  +++EEE+         ++E+ +R  +   A  P  E+R  
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796

Query: 280 ILREEFTSRMHQRFL 294
            LR E   +  QRFL
Sbjct: 797 QLRAEERQQREQRFL 811



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 16/114 (14%)

Query: 220  LSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERL 279
            L +LL +  E    Q+R   QQ +     EE+ E E+  E  +R  K         EE+ 
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK-------SQEEKQ 1319

Query: 280  ILREEFTSRMHQRFLDGKDGDFD--YSTVDDNPDFDNLDIVARDEEERYFDEEE 331
            +LREE   +  ++  D K  + +      ++ P       + R E +R F EEE
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQP-------LRRQERDRKFREEE 1366



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 10/110 (9%)

Query: 226  QSYEERELQQRLLQQQE----EEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLIL 281
            Q  +ERE QQ   Q+++    EEE  L  +E E+    +  R  ++ E  + + EE+ + 
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685

Query: 282  REEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
            R+E   +  +     +  + +   + +         + R E ER F EEE
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQ------LRRQELERKFREEE 1729



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 30/196 (15%)

Query: 155  RNRRYAALRELIQGGEY-----------FSDEQMRFRAPLLYEQYIGQYLTQEELSARTP 203
            R+R++    +L+Q GE            F +E+ + R     ++   ++L +E+   R  
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR----QERERKFLQEEQQLRRQE 1720

Query: 204  THQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEAC--------LEEEEEEE 255
              +  +     R       L  Q    + L++  L+ + EE+            EEE+  
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR 1780

Query: 256  DSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNL 315
               EE Q   ++S+    + E+    REE   R  QR  DGK     Y   ++    +  
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR--DGK-----YRWEEEQLQLEEQ 1833

Query: 316  DIVARDEEERYFDEEE 331
            +   R E +R +  EE
Sbjct: 1834 EQRLRQERDRQYRAEE 1849



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 25/94 (26%)

Query: 224 LLQSYEER-----------ELQQRL-------LQQQEEEEACLEEEEEEED-------SD 258
           LL+  EER            L+QRL       L+Q+E  E  L+ EE EE+       S+
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637

Query: 259 EEDQRSGKDSEAWVPDSEERLILREEFTSRMHQR 292
           E+++R  +       +  E+ + REE   R+ QR
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQR 671



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 45/194 (23%), Positives = 79/194 (40%), Gaps = 19/194 (9%)

Query: 147  PRTLRTRLRNRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQ 206
            P   R + R R+     EL Q  E    E+   R     E+   QY  +EE+        
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER---QYREEEEVQQEEEQLL 1154

Query: 207  PPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGK 266
              +P    R       L  Q  EE ELQQ   Q   EE+    +E E +  +EE+ +  K
Sbjct: 1155 REEPEKRRR-----QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209

Query: 267  DSEAWVPDSEERLILR------EEFTSRMHQRFLDGKDGD----FDYSTVDDNPDFDNLD 316
              + +  D ++R  L+      +E   R ++ +  G++ +     + S + D     +L 
Sbjct: 1210 RKQRY-RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268

Query: 317  IVARDEEERYFDEE 330
             +  +++ER  ++E
Sbjct: 1269 HLLGEQQERDREQE 1282



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 38/190 (20%), Positives = 73/190 (38%), Gaps = 11/190 (5%)

Query: 146  RPRTLRTRLRNRRYAALRELIQGGEYF----SDEQMRFRAPLLYEQYIGQYLTQEELSAR 201
            R    R +  +R++    +L+Q  E       +   +FR   L  Q  G+   +EE   R
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384

Query: 202  TPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEED 261
                +        +  C       Q  E++  Q R  + +EEE+    +E + +  +EE 
Sbjct: 1385 RQERERKFLKEEQQLRC-------QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437

Query: 262  QRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARD 321
            Q   ++ E    + E++L        R  ++ L  ++    +    D    +    + R 
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497

Query: 322  EEERYFDEEE 331
            E +R F E+E
Sbjct: 1498 ERDRKFREQE 1507



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 18/139 (12%)

Query: 209 KPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLE--------EEEEEEDSDEE 260
           +PG   R         L   EE+  +Q  L+Q++ +    E        +E EE  ++EE
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191

Query: 261 DQRSGKDSEA-WVPDSE-----ERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDN 314
             +S K  E    PD E     E L LR +      Q+  + +D  F     ++  ++  
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ---EEEEKEWRK 248

Query: 315 LDIVARDEEERYFDEEEPE 333
            + V R EEE+   EEEP+
Sbjct: 249 RETVLRKEEEK-LQEEEPQ 266



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 19/66 (28%), Positives = 32/66 (48%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEF 285
           +  EER  QQ   +Q+E  E  L  E+EEE  +++ +R  ++         E+ + RE+ 
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388

Query: 286 TSRMHQ 291
             R  Q
Sbjct: 389 LRREQQ 394



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 19/53 (35%), Positives = 27/53 (50%)

Query: 224 LLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSE 276
           L +  EE  L+QRL ++ EEE    E  EEE++   E  +S      W  +SE
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 33/138 (23%), Positives = 63/138 (45%), Gaps = 12/138 (8%)

Query: 150  LRTRLRNRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPK 209
            LR + R+R++    +L Q  E   ++Q+R       ++   ++  +E+L       Q   
Sbjct: 1764 LRRQERDRKFREEEQLRQERE---EQQLRS------QESDRKFREEEQLRQEREEQQLRP 1814

Query: 210  PGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEE---EEEEDSDEEDQRSGK 266
                G+       L L+  E+R  Q+R  Q + EE+   +E+   EE+E   EE+Q+  +
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874

Query: 267  DSEAWVPDSEERLILREE 284
            + E  + +   R   +EE
Sbjct: 1875 ERERKLREEHIRRQQKEE 1892



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 8/72 (11%)

Query: 229 EERELQQRL-----LQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEER---LI 280
           EE + QQRL     L++++EEE   ++EE  E  +  +Q+  +  +    + EER    +
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351

Query: 281 LREEFTSRMHQR 292
            RE+   R  Q+
Sbjct: 352 RREQEEERREQQ 363



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/125 (23%), Positives = 53/125 (42%), Gaps = 18/125 (14%)

Query: 224 LLQSYEERELQQRLLQQQE--------EEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDS 275
           L +  EE  LQQRL  +Q+         E+    EEE+  + +  +QR  ++ E    + 
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE----ER 574

Query: 276 EERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDA 335
            ++L+ REE   R  QR    ++   +     +  +     +   +  E+    EEPE+ 
Sbjct: 575 RDQLLKREE--ERRQQRLKREQEERLEQRLKREEVE----RLEQEERREQRLKREEPEEE 628

Query: 336 PSPEL 340
              +L
Sbjct: 629 RRQQL 633



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%)

Query: 226 QSYEERELQQRLLQQQEEEEACLEEEEEE------EDSDEEDQRSGKDSEAWVPDSEERL 279
           Q  E RE Q+R  QQ+E  E  L  E+EE          EE++R  +       +  E+ 
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376

Query: 280 ILREEFTSRMHQ 291
           + RE+   R  Q
Sbjct: 377 LRREQQLRREQQ 388



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 223 LLLQSYEERELQQR----LLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEER 278
           L L+  E RE Q+R    L ++QEE      + +EEE+  ++  RS +       +  E+
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548

Query: 279 LILREE 284
           L+ REE
Sbjct: 549 LLKREE 554



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 24/127 (18%)

Query: 223  LLLQSYEERELQQRLLQQQEEEEACLEEEEEE----EDSD----EEDQRSGKDSEAWVPD 274
            LL +  EE+  +Q   ++  EEE  L+E EE+    ++ D    EE+ R  +    ++ +
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE 1379

Query: 275  SE-------ERLILREEFTSRMHQRFLD-GKDGDFDYSTVDDNPDFDNLDIVARDEEERY 326
             +       ER  L+EE   R  +R     +D D  +   +          ++R E +R 
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ--------LSRQERDRK 1431

Query: 327  FDEEEPE 333
            F EEE +
Sbjct: 1432 FREEEQQ 1438



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 16/68 (23%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 224 LLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILRE 283
           L +  +E E QQ+ L+++++     EEE  E+  +  +Q+  ++ +    +  E+ + RE
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ---EERREQQLRRE 342

Query: 284 EFTSRMHQ 291
           +   R  Q
Sbjct: 343 QEERREQQ 350



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 31/135 (22%), Positives = 55/135 (40%), Gaps = 10/135 (7%)

Query: 174 DEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEEREL 233
           ++Q+R       EQ + +   +E L  R  + Q  +     R    L     +  E+   
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563

Query: 234 QQRLLQQQEEEEACLEEEEEE--------EDSDEEDQRSGKDSEAWVPDSE--ERLILRE 283
           +QRL ++QEE    L + EEE        E  +  +QR  ++    +   E  E+ + RE
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623

Query: 284 EFTSRMHQRFLDGKD 298
           E      Q+ L  ++
Sbjct: 624 EPEEERRQQLLKSEE 638



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 9/118 (7%)

Query: 225  LQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREE 284
            LQ  ++   Q+R  Q++++ +    EEE+     EE Q S ++ +      E+++  +E+
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593

Query: 285  FTSRMH-QRFLDGKDGDFDYSTVDDNPDFDNLDIVA--------RDEEERYFDEEEPE 333
                M  ++ L  ++G        D    ++  ++         R E +R F EEEP+
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%)

Query: 224 LLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEER-LILR 282
           L +  + R  QQ   +QQ   E  L  E+EEE  +++ ++  ++        E R  + R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460

Query: 283 EEFTSRMHQ 291
           EE T R  Q
Sbjct: 461 EEETERHEQ 469



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 24/113 (21%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 226  QSYEERELQQRLLQQQE----EEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLIL 281
            Q    +E QQ+L Q+++    E+E  L+E EE++   +E  R   + E  +   E    L
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661

Query: 282  REEFTSRM---HQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEE 331
            R +   +     Q   +G++        D     +   +  ++ E ++  EE+
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714


>gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 2/42 (4%)

Query: 232 ELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVP 273
           EL    +++ EE+E   EE+EEEE+ DEE+ ++G + + W P
Sbjct: 627 ELSGEEMEESEEDEE--EEDEEEEEEDEEESKAGGEDQLWRP 666


>gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 2/42 (4%)

Query: 232 ELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVP 273
           EL    +++ EE+E   EE+EEEE+ DEE+ ++G + + W P
Sbjct: 627 ELSGEEMEESEEDEE--EEDEEEEEEDEEESKAGGEDQLWRP 666


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 13/122 (10%)

Query: 229 EERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSR 288
           +E E +  +     +  A     E+E+D D+ED     D E    DSEE  +       +
Sbjct: 162 DEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEE--DDSEEEAMETTPAKGK 219

Query: 289 MHQRFL--------DGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPEL 340
              + +        + +D + D    DD+ D D+ D    D+EE   +EEE E+ P  E 
Sbjct: 220 KAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEE---EEEEEEEEPVKEA 276

Query: 341 DG 342
            G
Sbjct: 277 PG 278



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 17/120 (14%), Positives = 58/120 (48%), Gaps = 8/120 (6%)

Query: 194 TQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEE 253
           ++EE    TP        + G+ A  +  +  ++  E E ++   + +++++   +E+++
Sbjct: 206 SEEEAMETTP--------AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257

Query: 254 EEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFD 313
           +ED +EE++   ++     P   ++ + +++      ++ ++G +    ++    N +F+
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFN 317


>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
           [Homo sapiens]
          Length = 695

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 4/108 (3%)

Query: 238 LQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQRFLDGK 297
           + ++EEEE   EEEEE+E+ D +  +S   +EA + D  E  +  ++      +  ++ +
Sbjct: 212 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDR 271

Query: 298 DGDFDYSTVDD----NPDFDNLDIVARDEEERYFDEEEPEDAPSPELD 341
           D  +D    DD    NP     D    D+E  +  +  P   P+ ++D
Sbjct: 272 DYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKVPPTPLPTNDVD 319


>gi|31543392 peroxisome proliferator-activated receptor gamma,
           coactivator 1 beta [Homo sapiens]
          Length = 1023

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 23/86 (26%)

Query: 202 TPTHQPPKP----GSPGRP---------ACPLSN--------LLLQSYEERELQQRLLQQ 240
           TP  +P  P     SPGRP         A P S         L L+   E     RL QQ
Sbjct: 370 TPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQ 429

Query: 241 QEEEEACLEEEEEEEDSDEEDQRSGK 266
           +EE+E   EEEEEEE+  EE++  G+
Sbjct: 430 EEEDEE--EEEEEEEEEKEEEEEWGR 453



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 200 ARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQR---LLQQQEEEEACLEEEEEEED 256
           A+ P  +  +    G P  P  + LL+ +E R    +   LL+   EEE     +  E D
Sbjct: 732 AQAPGREEDRSCDAGAP--PKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYD 789

Query: 257 SDEEDQRSGKDSEAWVPDSEE 277
           +  ED  S     +++P+ EE
Sbjct: 790 TVFEDSSSSSGESSFLPEEEE 810



 Score = 28.5 bits (62), Expect = 9.1
 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 4/28 (14%)

Query: 234 QQRLLQQQEEEEACLEEEEEEEDSDEED 261
           +   L ++EEEE     EEEEED +EED
Sbjct: 801 ESSFLPEEEEEEG----EEEEEDDEEED 824


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,058,590
Number of Sequences: 37866
Number of extensions: 877524
Number of successful extensions: 20169
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 417
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 9016
Number of HSP's gapped (non-prelim): 5238
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.