Guide to the Human Genome
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Search of human proteins with 163937854

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
         (861 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                1718   0.0  
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                1456   0.0  
gi|189491742 ataxin 7 isoform b [Homo sapiens]                        494   e-139
gi|4506797 ataxin 7 isoform a [Homo sapiens]                          489   e-138
gi|93277115 ataxin 7-like 2 [Homo sapiens]                            333   4e-91
gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]                  252   9e-67
gi|91982772 mucin 17 [Homo sapiens]                                    65   4e-10
gi|167736355 mucin 4 isoform a [Homo sapiens]                          62   2e-09
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        59   1e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        58   4e-08
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              57   1e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   5e-07
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    54   8e-07
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        52   2e-06
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    52   3e-06
gi|161019170 mucin 5AC [Homo sapiens]                                  51   4e-06
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    51   4e-06
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       51   4e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    51   5e-06
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    50   7e-06
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         50   7e-06
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         50   7e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   7e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   50   1e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   50   1e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   50   1e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    50   1e-05
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             49   2e-05

>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 1718 bits (4449), Expect = 0.0
 Identities = 861/861 (100%), Positives = 861/861 (100%)

Query: 1   MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD 60
           MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD
Sbjct: 1   MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD 60

Query: 61  NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCER 120
           NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCER
Sbjct: 61  NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCER 120

Query: 121 RHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQH 180
           RHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQH
Sbjct: 121 RHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQH 180

Query: 181 TVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPL 240
           TVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPL
Sbjct: 181 TVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPL 240

Query: 241 IKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVL 300
           IKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVL
Sbjct: 241 IKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVL 300

Query: 301 DPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE 360
           DPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE
Sbjct: 301 DPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE 360

Query: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
           ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT
Sbjct: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420

Query: 421 PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV 480
           PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV
Sbjct: 421 PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV 480

Query: 481 FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSA 540
           FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSA
Sbjct: 481 FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSA 540

Query: 541 VYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKA 600
           VYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKA
Sbjct: 541 VYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKA 600

Query: 601 PSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSS 660
           PSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSS
Sbjct: 601 PSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSS 660

Query: 661 SLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRT 720
           SLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRT
Sbjct: 661 SLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRT 720

Query: 721 SLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKR 780
           SLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKR
Sbjct: 721 SLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKR 780

Query: 781 KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840
           KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS
Sbjct: 781 KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840

Query: 841 ISSPGHSRQNTNRTGRIRTLP 861
           ISSPGHSRQNTNRTGRIRTLP
Sbjct: 841 ISSPGHSRQNTNRTGRIRTLP 861


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score = 1456 bits (3769), Expect = 0.0
 Identities = 737/738 (99%), Positives = 737/738 (99%), Gaps = 1/738 (0%)

Query: 125 MCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFP 184
           MCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFP
Sbjct: 1   MCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFP 60

Query: 185 AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
           AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV
Sbjct: 61  AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 120

Query: 245 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 304
           LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET
Sbjct: 121 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 180

Query: 305 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPS 364
           KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPS
Sbjct: 181 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPS 240

Query: 365 QSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPP 424
           QSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPP
Sbjct: 241 QSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPP 300

Query: 425 LPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRR 484
           LPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRR
Sbjct: 301 LPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRR 360

Query: 485 WDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLP 544
           WDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLP
Sbjct: 361 WDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLP 420

Query: 545 SAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAV 604
           SAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAV
Sbjct: 421 SAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAV 480

Query: 605 SPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
           SPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT
Sbjct: 481 SPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT 540

Query: 665 SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPG 724
           SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPG
Sbjct: 541 SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPG 600

Query: 725 GPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSS 784
           GPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSS
Sbjct: 601 GPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSS 660

Query: 785 SSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 844
           SSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP
Sbjct: 661 SSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 720

Query: 845 GHSRQ-NTNRTGRIRTLP 861
           GHSRQ NTNRTGRIRTLP
Sbjct: 721 GHSRQKNTNRTGRIRTLP 738


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score =  494 bits (1272), Expect = e-139
 Identities = 357/903 (39%), Positives = 487/903 (53%), Gaps = 107/903 (11%)

Query: 18  GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75
           G G       AMAT+   R +PSPE  LG+ W+ W++A+KL   D  +L+E+ KE GK+R
Sbjct: 64  GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123

Query: 76  EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPVSP 135
           EVM L +EDM +FG  PAHDDFYLVVC+ CNQVVKPQ FQSH ERRH S  +P P  V P
Sbjct: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKP-PLAVPP 182

Query: 136 AS--NPRTSLVQVKTKACLSGHHS--------ASSTSKPFKTPKDNLLTSSSKQHTVFPA 185
            S  +   SL + K  +    + S        +SS+SK  K+PK+ L    + +  + P 
Sbjct: 183 TSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTR-PMHPI 241

Query: 186 KGSR-DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
           + SR     +  P V +EKI    K DG  +K     T   + SS     ++ P + KP 
Sbjct: 242 QQSRVPHGRIMTPSVKVEKIH--PKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPT 299

Query: 245 LMSKSVPPSPEKILNGKGI-LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303
           L      PSP +ILNGKG+  P T++KK ++ + N     +RLSEREFDP+ HCGV+D +
Sbjct: 300 L------PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLD 353

Query: 304 TKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV---KDKEHLLTSTRE 360
           TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+LLAEHK K+REKE+    D +      R+
Sbjct: 354 TKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRD 413

Query: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS--ANSISSSTSSNHSG 418
             P+    +Q+      G    E K    +K +P    LPRP    A    S+       
Sbjct: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473

Query: 419 H-TPEPPLPPVGGDLASRLSSDEGEMDGADES-EKLDCQFSTHHPRPLAFCSFGSRLMGR 476
           H +P PPLP    + ASRLSS+EGE D  +ES EKLDC +S HHP+P +FC+FGSR +GR
Sbjct: 474 HESPHPPLPAT--EPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGR 531

Query: 477 GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQ-PF 535
           GYYVFD RW+R R ALN MVEKHLN+Q+WKKIP     P+PS  + I+T +P      P 
Sbjct: 532 GYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP-----PVPSTTSPISTRIPHRTNSVPT 586

Query: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595
           S     YL +A +S   TS  +++S  +       SP+  ++ +H T      A    MD
Sbjct: 587 SQCGVSYLAAATVS---TSPVLLSSTCI-------SPNSKSVPAHGTTLNAQPAASGAMD 636

Query: 596 -----------STFKAPSAVSPIPAVIPSP-SHKPSKTKTSKSSKVKDLS---------T 634
                      S+  +PS  S + +V  SP S KP K K+SKS + K+ S         +
Sbjct: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS 696

Query: 635 RSDESPSNKKRKPQSST---SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            S    S KKRK  S     SSSSSSSSSS   S+ S      +KNCV +         +
Sbjct: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES-----FRKNCVAH---------S 742

Query: 692 APPY-------NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCP 744
            PPY       +S+ ++   N  + ++ + + SGR    G PA+ ++++  +  SSDS  
Sbjct: 743 GPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS-T 801

Query: 745 LSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNS-------SSSSKACKITKMPG 797
           LS+      + +L + SH + S      DK  GKKRK S       +SSSK  K+ K+P 
Sbjct: 802 LSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPA 861

Query: 798 MNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSL--ALSQSSPSS--ISSPGHSRQNTNR 853
           +N+VH K+    +      +NS+   Q   +  L   +S +SP S  + S G S    N 
Sbjct: 862 VNNVHMKH-TGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENS 920

Query: 854 TGR 856
           TGR
Sbjct: 921 TGR 923


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score =  489 bits (1260), Expect = e-138
 Identities = 342/848 (40%), Positives = 465/848 (54%), Gaps = 102/848 (12%)

Query: 18  GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75
           G G       AMAT+   R +PSPE  LG+ W+ W++A+KL   D  +L+E+ KE GK+R
Sbjct: 64  GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123

Query: 76  EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPVSP 135
           EVM L +EDM +FG  PAHDDFYLVVC+ CNQVVKPQ FQSH ERRH S  +P P  V P
Sbjct: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKP-PLAVPP 182

Query: 136 AS--NPRTSLVQVKTKACLSGHHS--------ASSTSKPFKTPKDNLLTSSSKQHTVFPA 185
            S  +   SL + K  +    + S        +SS+SK  K+PK+ L    + +  + P 
Sbjct: 183 TSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTR-PMHPI 241

Query: 186 KGSR-DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
           + SR     +  P V +EKI    K DG  +K     T   + SS     ++ P + KP 
Sbjct: 242 QQSRVPHGRIMTPSVKVEKIH--PKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPT 299

Query: 245 LMSKSVPPSPEKILNGKGI-LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303
           L      PSP +ILNGKG+  P T++KK ++ + N     +RLSEREFDP+ HCGV+D +
Sbjct: 300 L------PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLD 353

Query: 304 TKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV---KDKEHLLTSTRE 360
           TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+LLAEHK K+REKE+    D +      R+
Sbjct: 354 TKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRD 413

Query: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS--ANSISSSTSSNHSG 418
             P+    +Q+      G    E K    +K +P    LPRP    A    S+       
Sbjct: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473

Query: 419 H-TPEPPLPPVGGDLASRLSSDEGEMDGADES-EKLDCQFSTHHPRPLAFCSFGSRLMGR 476
           H +P PPLP    + ASRLSS+EGE D  +ES EKLDC +S HHP+P +FC+FGSR +GR
Sbjct: 474 HESPHPPLPAT--EPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGR 531

Query: 477 GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQ-PF 535
           GYYVFD RW+R R ALN MVEKHLN+Q+WKKIP     P+PS  + I+T +P      P 
Sbjct: 532 GYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP-----PVPSTTSPISTRIPHRTNSVPT 586

Query: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595
           S     YL +A +S   TS  +++S  +       SP+  ++ +H T      A    MD
Sbjct: 587 SQCGVSYLAAATVS---TSPVLLSSTCI-------SPNSKSVPAHGTTLNAQPAASGAMD 636

Query: 596 -----------STFKAPSAVSPIPAVIPSP-SHKPSKTKTSKSSKVKDLS---------T 634
                      S+  +PS  S + +V  SP S KP K K+SKS + K+ S         +
Sbjct: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS 696

Query: 635 RSDESPSNKKRKPQSST---SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            S    S KKRK  S     SSSSSSSSSS   S+ S      +KNCV +         +
Sbjct: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES-----FRKNCVAH---------S 742

Query: 692 APPY-------NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCP 744
            PPY       +S+ ++   N  + ++ + + SGR    G PA+ ++++  +  SSDS  
Sbjct: 743 GPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS-T 801

Query: 745 LSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNS-------SSSSKACKITKMPG 797
           LS+      + +L + SH + S      DK  GKKRK S       +SSSK  K+ K+P 
Sbjct: 802 LSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPA 861

Query: 798 MNSVHKKN 805
           +N+VH K+
Sbjct: 862 VNNVHMKH 869


>gi|93277115 ataxin 7-like 2 [Homo sapiens]
          Length = 722

 Score =  333 bits (854), Expect = 4e-91
 Identities = 269/820 (32%), Positives = 375/820 (45%), Gaps = 144/820 (17%)

Query: 22  KQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLN 81
           +++   AMA L+R+VPS + F G+ WSSW++ A L  +D  +LEE+ K   K  + M L 
Sbjct: 4   RERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLI 62

Query: 82  KEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMC----RPSPSPVSPAS 137
           KEDM +FGH PAHDDFYLVVC+ C+QVVKPQ FQ HCERRHG +     R  P P +PAS
Sbjct: 63  KEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPAS 122

Query: 138 NPRTSLVQVKTKACLS-GHHSASSTSK-----------PFKTPKDNLLTSSSKQHTVFPA 185
           + +  +V  +  AC + G    SS  K           P KT KDNL           P 
Sbjct: 123 SQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQ---------PG 173

Query: 186 KGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVL 245
             ++D P  P P+    K P        N+++       + +  +S  A  +PP      
Sbjct: 174 GLTKDSPGKP-PMAPPSKEP----PGRENIEI-------IPSEGSSHWAEGSPP------ 215

Query: 246 MSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETK 305
                                   +K  +GT+   K +R+++ +E D N+ CGV++PETK
Sbjct: 216 ------------------------EKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETK 251

Query: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQ 365
           K CTR LTCK HS+  RR V GR K FD+L+AE KA SR+ E   KE       ++L   
Sbjct: 252 KICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGE-SPKEKSPGRKEQVLERP 310

Query: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEP-- 423
           S     S+   +  + P    +  AK   P   LPR S A+S S        G   +P  
Sbjct: 311 SQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPR-SRASSESELDDEGPCGGDGDPGL 369

Query: 424 ---PLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV 480
              P+P  G   +S  S +EG  D  D     DC ++T  PRP AFC+FGSRL+  G YV
Sbjct: 370 FPFPMPRGGTQASSEESEEEGTSD--DLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYV 427

Query: 481 FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSA 540
           F RR DRF  AL+SM+E+HL++ MWKKIPPAA+     P AH+     ++ L P S  + 
Sbjct: 428 FSRRLDRFCSALSSMLERHLSTHMWKKIPPAAE-----PPAHLVNSPLSAPLSPSSTGTC 482

Query: 541 VYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKA 600
             LP   +     +S   T   L             + S+    P VAA  S  +    +
Sbjct: 483 PRLPGPTLRPACPASMPPTKDNL-------------VPSYPAGSPSVAAACSQAECMGGS 529

Query: 601 PSAVSPIPAVIPSPS-HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSS 659
            +  SP+PA  PSPS  K   +K SKSSK KD      E+PS K++     T+       
Sbjct: 530 QAITSPLPANTPSPSFSKLPPSKASKSSKGKD--GVEVEAPSRKRKLSPGPTTL------ 581

Query: 660 SSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGR 719
                          K+ C+L  +                     +G   LSAK + +  
Sbjct: 582 ---------------KRTCILEPTG----------------KGKPSGCRGLSAKTKTALS 610

Query: 720 TSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLS--FDKSEG 777
             L G     V++ G +        L  P  A    +   A H A  +LP +   ++   
Sbjct: 611 MGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPA-KALPTNCLSEEEVA 669

Query: 778 KKRKNSSS-----SSKACKITKMPGMN-SVHKKNPPSLLA 811
           KKRKN ++      +K C+      +  SV +K P   LA
Sbjct: 670 KKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALA 709


>gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]
          Length = 146

 Score =  252 bits (644), Expect = 9e-67
 Identities = 124/146 (84%), Positives = 127/146 (86%)

Query: 1   MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD 60
           MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD
Sbjct: 1   MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSD 60

Query: 61  NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCER 120
           NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHC R
Sbjct: 61  NVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGR 120

Query: 121 RHGSMCRPSPSPVSPASNPRTSLVQV 146
           +  +      S   P S+      QV
Sbjct: 121 KQDNRRNEGISRSGPESSQAIEKHQV 146


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 170/774 (21%), Positives = 293/774 (37%), Gaps = 120/774 (15%)

Query: 131  SPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLL---TSSSKQHTVFPAKG 187
            S  S  S P TS V V T+  +S   S  ST     TP D  +   TS+    +   A+G
Sbjct: 1094 STYSEGSTPLTS-VPVSTRLVVSSEASTLST-----TPVDTSIPVTTSTEASSSPTTAEG 1147

Query: 188  SRDKPCVP----VPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKP 243
            +      P     P+ S+     LV +  AN  +++T   + +  +TS+ A S PP  + 
Sbjct: 1148 TSIPTSPPSEGTTPLASMPVSTTLVVSSEANT-LSTTPVDSKTQVATSTEASSPPPTAEV 1206

Query: 244  VLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNS----NKPYRRLSEREFDPNKHCGV 299
              M  S P      L    +  T +     +    S    + P    +E    P    G 
Sbjct: 1207 TSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT 1266

Query: 300  -LDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTST 358
             L   T    +  LT    S +              L+   +A +      D +  + ++
Sbjct: 1267 SLPTSTTSEGSTLLTSIPVSTT--------------LVTSPEASTLLTTPVDTKGPVVTS 1312

Query: 359  REILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSR-------------PPNSVLPRPSSA 405
             E+  S +     S+  S+ S G  P  + P  +              P ++  P  +S 
Sbjct: 1313 NEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTST 1372

Query: 406  NSISSSTSSNHS---------GHTPEPPLP----PVGGDLASRLSSD--EGEMDGADESE 450
             + SS T+S  +         G TP   +P    PV    AS LS+   +    G   +E
Sbjct: 1373 EACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAE 1432

Query: 451  KLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPP 510
                  +T  P      S  +     G      +       +++    +  +      P 
Sbjct: 1433 ------ATSSPTTAEGISIPTSTPSEG------KTPLKSIPVSNTPVANSEASTLSTTPV 1480

Query: 511  AADSPLPSPAAHITTPVPASVLQ-PFSNPS--AVYLPSAPISSRLTSSYIMTSAMLSNAA 567
             ++SP+ +  A  ++P PA       S PS  +  L S P+S+   +S  + S  LS   
Sbjct: 1481 DSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINS--LSTTP 1538

Query: 568  FVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSS 627
             VTS  P    S  ++ P  A   S+  ST+   S  +P+ ++       P  T    SS
Sbjct: 1539 AVTST-PVTTYSQASSSPTTADGTSMQTSTYSEGS--TPLTSL-------PVSTMLVVSS 1588

Query: 628  KVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALN 687
            +   LST    +P + K +  +ST +SSS+++     ++S+P  G    + +L +     
Sbjct: 1589 EANTLST----TPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG----SPLLTSIPVST 1640

Query: 688  SYQAAPPYNSLSVH--NSNNGV---SPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDS 742
            +  A+P  ++LS    +SN+ V   + +S+   P+  TS+P              G +  
Sbjct: 1641 TPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTST--------YTEGRTPL 1692

Query: 743  CPLSVPSLALHAGDLSLASHNAV-SSLPL--------SFDKSEGKKRKNSSSSSKACKIT 793
              ++V +  + +  +S  S   V +S P+        S   SEG    NS+ S     +T
Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT 1752

Query: 794  KMPGMNSVHKKNPPSLLAPVPDPVNS--TSSRQVGKNSSLALSQSSPSSISSPG 845
             +P   +    +  S L+  P   ++  T+S +   + + A   S P+S  S G
Sbjct: 1753 SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 1806



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 177/761 (23%), Positives = 272/761 (35%), Gaps = 93/761 (12%)

Query: 131  SPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSK--------QHTV 182
            S  S  S   TS+    T    S  +S S+T     TP      +SS           T 
Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS 1566

Query: 183  FPAKGSRDKPCVPVP---VVSLEKIPNLVKADGANVKMNSTTTTAVSASST---SSSAVS 236
              ++GS     +PV    VVS E   N +     + K   T +T  S+S+T   SS  +S
Sbjct: 1567 TYSEGSTPLTSLPVSTMLVVSSEA--NTLSTTPIDSKTQVTASTEASSSTTAEGSSMTIS 1624

Query: 237  TPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKH 296
            TP    P+L S  V  +P        +  T +D         SN P    +E    P   
Sbjct: 1625 TPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD---------SNSPVITSTEVSSSPTPA 1675

Query: 297  CGVLDP-----ETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDK 351
             G   P     E + P T S+T +T  +                 A     +      D 
Sbjct: 1676 EGTSMPTSTYTEGRTPLT-SITVRTTPV-----------------ASSAISTLSTTPVDN 1717

Query: 352  EHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSS 411
               +T++ E   S +     S+  S+ S G  P  + P  + P  S      SA  I +S
Sbjct: 1718 STPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS 1777

Query: 412  TSSNHSGHTPEPPLPPVGGDL-ASRLSSDEGEMDGADESEKL--DCQFSTHHPRPLAFCS 468
            T    S      P    G  +  S LS     +     S  L  + + ST    P+   S
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS 1837

Query: 469  --------FGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPA 520
                      S     G  +          AL S+            +  +  + L +  
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTT------VASSETNTLSTTP 1891

Query: 521  AHITTPVPASVLQPFSNPSAVYLPSAPISSR------LTSSYIMTSAMLSNAAFVTSPDP 574
            A  +TPV  +  Q  S+P+     S P S+       LTS  + T+ + S+     S   
Sbjct: 1892 AVTSTPV-TTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTL 1950

Query: 575  SALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLST 634
            +   +  T +   +++ +  D T     A S     + S    P  T    SS+   LST
Sbjct: 1951 ADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTS---MPLSTTLVVSSEASTLST 2007

Query: 635  RSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS----PLSGPHKKNCVLNASSALNSYQ 690
               ++ +      + S SS +++  +S+QTS  S    PL+G    +  L  SS  N+  
Sbjct: 2008 TPVDTSTPATTSTEGS-SSPTTAGGTSIQTSTPSERTTPLAGM-PVSTTLVVSSEGNTLS 2065

Query: 691  AAPPYNSLSVHNSNNGVSPLSAKLEPSGRT-SLPGGPADIVRQVGAVGGSSDSCPLSVPS 749
              P  +   V NS    S  SA  E S  T S P   + ++  +        S   S  S
Sbjct: 2066 TTPVDSKTQVTNSTEASS--SATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLS 2123

Query: 750  LALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSL 809
                  +  + +   VSS P+    +EG   + S+ S +   +T MP   +V   +  S 
Sbjct: 2124 TTPVDSNSPVITSTEVSSSPIP---TEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIST 2180

Query: 810  LAPVP----DPV-NSTSSRQVGKNS-SLALSQSSPSSISSP 844
            L+  P     PV NST +R     S   ++  S+PS  S+P
Sbjct: 2181 LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTP 2221



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 168/769 (21%), Positives = 279/769 (36%), Gaps = 143/769 (18%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGS 188
            S +PV   S P T+  + ++    S       TS P  TP +     +S           
Sbjct: 2182 STTPVD-TSTPVTNSTEARSSPTTS-----EGTSMPTSTPSEGSTPFTS----------- 2224

Query: 189  RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTP--PLIKPVLM 246
               P   +PVV+ E   + + A   +     TT+T  ++S T++   S P   L +    
Sbjct: 2225 --MPVSTMPVVTSE--ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP 2280

Query: 247  SKSVPPSPEKILNGK-GILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETK 305
              S+P S   + N +   L TT          +SN P+   +E    P            
Sbjct: 2281 LTSIPVSHTLVANSEVSTLSTT--------PVDSNTPFTTSTEASSPP------------ 2320

Query: 306  KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQ 365
             P     +  T + S       R      ++A  +  +      D    +T+  +   S 
Sbjct: 2321 -PTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSP 2379

Query: 366  SGPAQDSLLGSSGSSGPEPKVASPAKSRP-------PNSVLPRPSSANSISSSTSSNHSG 418
            +     S+  S+ S G  P  + P  + P        +S  P  +S   +++ST ++ S 
Sbjct: 2380 TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTS-TPVTTSTEASSSP 2438

Query: 419  HTPE----PPLPPVGG--DLASR-------LSSDEGEMDGADESEKLDCQFSTHHPR--- 462
             T E    P  PP  G   LAS        +SS+ G +             ST       
Sbjct: 2439 TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPT 2498

Query: 463  -------PLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSP 515
                   P++  S GS L                  L S+              P + +P
Sbjct: 2499 TAEDIVVPISTASEGSTL------------------LTSI--------------PVSTTP 2526

Query: 516  LPSPAAHI--TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            + SP A    TTPV ++     S   +    SA  +S  TS+Y   S  L +    T P 
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 574  PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPS-PSHKPSKTKTSKSSKVKDL 632
             S+  S  +  P V  ++ +  ST    ++ SP  A   S P   PS+  TS +S +   
Sbjct: 2587 ASSEASTLSTTP-VDTSIPVTTST---ETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642

Query: 633  STRSDESPSNKKRKPQSS----TSSSSSSSSSSLQTSLSSPLSGPHKKNCVLN---ASSA 685
               +    S     P  +    T+S+ +SSS +     S P S P +++  L     S+ 
Sbjct: 2643 MPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTT 2702

Query: 686  LNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPL 745
            L +   A   ++  V  S    +P++   E S   +   G +  +R      GS+    +
Sbjct: 2703 LLANSEASTLSTTPVDTS----TPVTTSAEASSSPTTAEGTS--MRISTPSDGSTPLTSI 2756

Query: 746  SVPSLALHAGDLSLASHNAV-SSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKK 804
             V +L + + + S  S  AV +S+P++           +SSS    ++T MP        
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVT-------TSTEASSSPTTAEVTSMPTSTPSETS 2809

Query: 805  NPPSLLAPVPDPVNST--SSRQVGKNSSLALSQSSPSSISSPGHSRQNT 851
             P + +     PVN T  +S + G  S+  +  S+P + S+   S   T
Sbjct: 2810 TPLTSM-----PVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 148/735 (20%), Positives = 256/735 (34%), Gaps = 52/735 (7%)

Query: 129 SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGS 188
           +P P   A    T  V + T    S   S+S T+    T   +  +  S   T  PA   
Sbjct: 167 APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTM 226

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKP----- 243
           +      + +++     +      A    + TT    S S+++ S  STP    P     
Sbjct: 227 KVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVML 286

Query: 244 VLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303
           V+ S++   S         ++ +T         + ++ P    +E             P 
Sbjct: 287 VVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGS----------TPL 336

Query: 304 TKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE--I 361
           T  P + ++   T  +S     P        L+      S      +   +LTST     
Sbjct: 337 TSTPAS-TMPVATSEMSTLSITP---VDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGS 392

Query: 362 LPSQSGPAQDSLLGSSGSSGPEP-KVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
            P  + P    L+ SS +S      V S       +     P++A   S +TS+   G T
Sbjct: 393 TPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGST 452

Query: 421 PEPPLP----PVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGR 476
           P   +P    PV    AS LS+   +     +++      ++  P      S  +     
Sbjct: 453 PLTSMPVSTTPVASSEASNLSTTPVD----SKTQVTTSTEASSSPPTAEVNSMPTSTPSE 508

Query: 477 GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLP-SPAAHITTPVPASVLQPF 535
           G             ++++M      +      P    +P+  S  A  ++  P     P 
Sbjct: 509 GSTPLTS------MSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPT 562

Query: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595
           S PS    P       LT+  + T  ++S+ A  TS  P+   +  T     +++ +  +
Sbjct: 563 STPSEGSTP-------LTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAE 615

Query: 596 STFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSS 655
            T    S  S     I S S   +   +S++S +      S+   +       SST++  
Sbjct: 616 GTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG 675

Query: 656 SSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLE 715
           +S  +S  T  S+PL+     N  L ASS  ++    P   S  V  S    S  +    
Sbjct: 676 TSMPTSTYTEGSTPLTS-MPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADG 734

Query: 716 PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSS-LPLSFDK 774
            S  TS P   +  +  +      S +   S  +  L    L  ++H   S+    S   
Sbjct: 735 ASMPTSTPSEGSTPLTSMPV----SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTT 790

Query: 775 SEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNS--TSSRQVGKNSSLA 832
           +EG     S+ S  +  +T +P   +       S L+  P   NS  T+S +V  + + A
Sbjct: 791 TEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPA 850

Query: 833 LSQSSPSSISSPGHS 847
              S P+S  S G +
Sbjct: 851 EGTSMPTSTYSEGRT 865



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 152/742 (20%), Positives = 255/742 (34%), Gaps = 119/742 (16%)

Query: 132  PVSPASNPRTSL--VQVKTKACLSGHHSASSTS-----KPFKTPKDNLLTSSSKQHTVFP 184
            P+S AS   T L  + V T    S   S  ST+      P  T  +   +++S + T  P
Sbjct: 2506 PISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565

Query: 185  ----AKGSRDKPCVPV---PVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTS----SS 233
                ++GS     +PV   P+ S E   + +     +  +  TT+T  S+S T+    S 
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEA--STLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623

Query: 234  AVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDP 293
             +STP  +   L S  V   P        +  T +D +    T          +E    P
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 294  NKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEH 353
                G    E   P T  L   T                  LLA  +A +      D   
Sbjct: 2684 TSTPG----ERSTPLTNILVSTT------------------LLANSEASTLSTTPVDTST 2721

Query: 354  LLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTS 413
             +T++ E   S +     S+  S+ S G  P  +    + P  S      S  ++ +S  
Sbjct: 2722 PVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP 2781

Query: 414  SNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRL 473
               S    E    P   ++ S  +S   E               T  P            
Sbjct: 2782 VTTS---TEASSSPTTAEVTSMPTSTPSE---------------TSTP------------ 2811

Query: 474  MGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSP---LPSPAAHITTPVPAS 530
                              L SM   H          P A S    L +     +TPV  S
Sbjct: 2812 ------------------LTSMPVNHT---------PVASSEAGTLSTTPVDTSTPVTTS 2844

Query: 531  VLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAAT 590
              +  S+P+       PIS+    S ++TS  +S     +S   ++ +S T     +  T
Sbjct: 2845 T-KASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE--ASTLSTTPVDTSIPVT 2901

Query: 591  LSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSS 650
             S   S+    +  + +P   PS    P  +    +  V      +  +     R P   
Sbjct: 2902 TSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPV-- 2959

Query: 651  TSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPL 710
            T+S+ +SSS +     S P+S P ++   L + S      A+   ++LS   ++   +P+
Sbjct: 2960 TTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTS-TPV 3018

Query: 711  SAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPL 770
            +   E S   +   G       +     S  S PL+  S+ +    +++   + +S+ P+
Sbjct: 3019 TTSTEASSSPTTAEGTG-----IPISTPSEGSTPLT--SIPVSTTPVAIPEASTLSTTPV 3071

Query: 771  SFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSS 830
              +       + SSS + A + T MP         P   L  VP      +S  +   S+
Sbjct: 3072 DSNSPVVTSTEVSSSPTPA-EGTSMPISTYSEGSTP---LTGVPVSTTPVTSSAISTLST 3127

Query: 831  LALSQSSPSSISSPGHSRQNTN 852
              +  S+P + S+  HS   T+
Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTS 3149



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 167/756 (22%), Positives = 254/756 (33%), Gaps = 99/756 (13%)

Query: 130  PSPVSPASNPRTSLVQVKTKACLSGHHSAS-----STSKPFKTPKDNLLTSSSKQHTVFP 184
            P   S AS   T+ V  +T    S   S+S      TS P  TP +     +S   +  P
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMP 2998

Query: 185  AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSA----VSTPPL 240
               S           +L + P       A+     TT+T  S+S T++      +STP  
Sbjct: 2999 VASSEAS--------TLSRTP-------ADTSTPVTTSTEASSSPTTAEGTGIPISTPSE 3043

Query: 241  IKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVL 300
                L S  V  +P  I     +  T +D         SN P    +E    P    G  
Sbjct: 3044 GSTPLTSIPVSTTPVAIPEASTLSTTPVD---------SNSPVVTSTEVSSSPTPAEGTS 3094

Query: 301  DP-----ETKKPCTR---SLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKE 352
             P     E   P T    S T  T S     +         +  +     S         
Sbjct: 3095 MPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM 3154

Query: 353  HLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS---ANSIS 409
               T +    P    P    L+ SS  S      A+P  +  P +     +S   A   S
Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLS---ATPVDTSTPVTTSTEATSSTTAEGTS 3211

Query: 410  SSTSSNHSGHTPEPPLP----PVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLA 465
              TS+   G TP   +P    PV    AS LS+        D +  L          P A
Sbjct: 3212 IPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTP-----VDSNTPLTTSTEASSSPPTA 3266

Query: 466  FCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITT 525
                       G  +           L SM            +  +  S L +  A  +T
Sbjct: 3267 ----------EGTSMPTSTPSEGSTPLTSMPVSTTT------VASSETSTLSTTPADTST 3310

Query: 526  PVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSP---DPSALMSHTT 582
            PV  +  Q  S+P     P A  +S  TS+Y   S  L+N +F T+P     ++ +S T 
Sbjct: 3311 PV-TTYSQASSSP-----PIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP 3364

Query: 583  AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSP-----SHKPSKTKTSKSSKVKDLSTRSD 637
                   T S   S     +  + IP   PS      +  P  T    SS+V  LST   
Sbjct: 3365 VDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLST--- 3421

Query: 638  ESPSNKKRKPQSSTSSSSS---SSSSSLQTSLSSPLSGP---HKKNCVLNASSALNSYQA 691
             +P +      +ST +SSS   +  +SL TS +S  S P      +    ASS  ++   
Sbjct: 3422 -TPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLST 3480

Query: 692  APPYNSLSVHNSN-NGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSL 750
             P   S  V  S+    SP +A++     ++   G   +     +    + S   ++ + 
Sbjct: 3481 TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT 3540

Query: 751  ALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNP--PS 808
             + +     +S  A SS       +      +  SSS    +     + S     P  PS
Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600

Query: 809  LLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 844
            +    P   ++ S+        + L  S+PS +S+P
Sbjct: 3601 VDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTP 3636



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 147/764 (19%), Positives = 261/764 (34%), Gaps = 130/764 (17%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLSGHHSA-SSTSKPFKTPKDNLLTSSSKQHTVFPAK 186
            P+ +P S  S P T +  V T   +S   S  S+T     TP    +T+S++  +   A+
Sbjct: 3155 PTSTP-SEGSTPLTYM-PVSTMLVVSSEDSTLSATPVDTSTP----VTTSTEATSSTTAE 3208

Query: 187  GSRDKPCVP----VPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIK 242
            G+      P     P+ S+      V +  A++ +++T   + +  +TS+ A S+PP  +
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI-LSTTPVDSNTPLTTSTEASSSPPTAE 3267

Query: 243  PVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDP 302
               M  S P      L    +  TT+     +           LS    D +        
Sbjct: 3268 GTSMPTSTPSEGSTPLTSMPVSTTTVASSETS----------TLSTTPADTSTPVTTYSQ 3317

Query: 303  ETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLL-LAEHKAKSREKEVKDKEHLLTSTREI 361
             +  P     T    S     + P     F    +   +A +      D    +T++ E 
Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEA 3377

Query: 362  LPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTP 421
              S +     S+  SS S G  P  + P  + P  S     S  N++S++          
Sbjct: 3378 SLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVS-----SEVNTLSTT---------- 3422

Query: 422  EPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVF 481
                 PV  +     S++        E   L    ++    PL+                
Sbjct: 3423 -----PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLS---------------- 3461

Query: 482  DRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHI--TTPVPASVLQPFSNPS 539
                                      I P + +P+ S  A    TTPV  S     S+P+
Sbjct: 3462 --------------------------IMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495

Query: 540  AVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSP---DPSALMSHTTAFPHVAATLSIMDS 596
                 +A ++S  TS+    S  L+N    T+P     ++ +S T    +   T S   S
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS 3555

Query: 597  TFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSS 656
            +  A   V+ +    PS       T    S+ V      +  +PS  +  P   T+S+ S
Sbjct: 3556 SSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP--VTTSTQS 3613

Query: 657  SSSSSLQTSLSSPLSGPHKKN---CVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAK 713
            +S+ +    ++ P+S P + +    ++  S+   +   A   ++L V  S   ++     
Sbjct: 3614 NSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVS 3673

Query: 714  LEP--------------SGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSL 759
              P               G T L   P    R V +  GS+ S P  V S  +     ++
Sbjct: 3674 SSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTR-VTSSEGSTLSTPSVVTSTPVTTSTEAI 3732

Query: 760  ASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMN----------------SVHK 803
            +S   + S  +S           ++       +T+ P  +                S   
Sbjct: 3733 SSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS 3792

Query: 804  KNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHS 847
             +P +L      P+++TS R    ++ L     SP S+ SP  +
Sbjct: 3793 SSPTTLEGTTTMPMSTTSER----STLLTTVLISPISVMSPSEA 3832



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 51/217 (23%), Positives = 85/217 (39%), Gaps = 26/217 (11%)

Query: 510  PAADSPLPSPAAHITTPVPASVLQPFSNP-SAVYLPSAPISSRLTSSYIMTSAMLSNAAF 568
            P+ D+   +P   + T +  SV+   S P + +++PS P++S     +  T+  +S    
Sbjct: 3908 PSTDTA-STPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVI 3966

Query: 569  VTSP--DPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKS 626
             ++    PS   S TT       T       F  P+  +  P    + S  PS  +T+  
Sbjct: 3967 TSTELNTPSTSSSSTT-------TSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSR 4019

Query: 627  SKVKDLSTRSDES-PSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSA 685
                  ST S  S P           + SS SS  S  TS + P + P            
Sbjct: 4020 GCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFP------------ 4067

Query: 686  LNSYQAAPPYNSLSVHNSN-NGVSPLSAKLEPSGRTS 721
              ++ + PP  S S    N   V+ ++ + +PS RT+
Sbjct: 4068 -PAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTT 4103



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 152/760 (20%), Positives = 253/760 (33%), Gaps = 119/760 (15%)

Query: 134  SPASNPRTSLVQVKTKACLSGHHSAS-----STSKPFKTPKDNLLTSSSKQHTVFPAKGS 188
            S AS   T+ V   T A  S   S+S      TS    TP +     +    +      S
Sbjct: 2000 SEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSS 2059

Query: 189  RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
                    PV S  ++ N  +A        S++ TA  +S T S+     PL+  + +S 
Sbjct: 2060 EGNTLSTTPVDSKTQVTNSTEA--------SSSATAEGSSMTISAPSEGSPLLTSIPLST 2111

Query: 249  SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPC 308
            +   SPE       +  T +D         SN P    +E    P               
Sbjct: 2112 TPVASPE----ASTLSTTPVD---------SNSPVITSTEVSSSPIP------------- 2145

Query: 309  TRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGP 368
            T   + +T + S RR           ++A     +      D    +T++ E   S +  
Sbjct: 2146 TEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS 2205

Query: 369  AQDSLLGSSGSSGPEPKVASPAKSRP----------------------PNSVLPRPSSAN 406
               S+  S+ S G  P  + P  + P                             P++A 
Sbjct: 2206 EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE 2265

Query: 407  SISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLA- 465
              S  TS+   G TP   + PV   L +            D +           P P A 
Sbjct: 2266 GTSIPTSTLSEGTTPLTSI-PVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAE 2324

Query: 466  FCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITT 525
              S  +     G                 +    +++ M   +     S L +  A  +T
Sbjct: 2325 GTSMPTSTSSEGN--------------TPLTRMPVSTTM---VASFETSTLSTTPADTST 2367

Query: 526  PVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFP 585
            PV  +  Q  S+P+     S P S+    S  +TS  +S    V+S   ++  S T    
Sbjct: 2368 PV-TTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS--EASTHSTTPVDT 2424

Query: 586  HVAATLSIMDSTFKAPSAVSPIPAVIPSP-----SHKPSKTKTSKSSKVKDLSTRSDESP 640
                T S   S+    +  + IP   PS      +  P  T    SS+   LST   ++ 
Sbjct: 2425 STPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484

Query: 641  SNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSV 700
            +         T+S+ +SSS +    +  P+S   + + +L +     +  A+P  ++LS 
Sbjct: 2485 T-------PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLST 2537

Query: 701  HNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLA 760
               ++  SP+    E S   +   G +              S P+S   LA      +L+
Sbjct: 2538 TPVDSN-SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS-TLS 2595

Query: 761  SHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMP---------GMNSVHKKNPP---- 807
            +    +S+P++           +SSS    K T MP          + S+     P    
Sbjct: 2596 TTPVDTSIPVT-------TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASS 2648

Query: 808  --SLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
              S L+  P    +  +   G +SS   ++ S    S+PG
Sbjct: 2649 EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPG 2688



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 168/773 (21%), Positives = 272/773 (35%), Gaps = 112/773 (14%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN---LLTSSSKQHTVFP 184
            P+ +P S  S P T++  V T+  +S   S +ST     TP D+   + TSS    +   
Sbjct: 561  PTSTP-SEGSTPLTNM-PVSTRLVVSSEASTTST-----TPADSNTFVTTSSEASSSSTT 613

Query: 185  AKGSRDKPCV----PVPVVSLEKIPNLVKADGAN------VKMNSTTTTAVSASSTSSSA 234
            A+G+             + S+     LV +  A+      V  N+  TT+  A+S+S++A
Sbjct: 614  AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTA 673

Query: 235  VSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTK----NSNKPYRRLSERE 290
              T        M  S        L    +  T +     +       +++ P    +E  
Sbjct: 674  EGTS-------MPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726

Query: 291  FDPNKHCGVLDP-----ETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSRE 345
              P    G   P     E   P T     KT   S   +         L  + H   S E
Sbjct: 727  SSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP---LDTSTHITTSTE 783

Query: 346  KEVKDKEHLLTSTREILPSQSGPAQDSL-LGSSGSSGPEPKVAS--PAKSRPP----NSV 398
                      TS     PS+  P   S+ +  +  + PE    S  P  S  P      V
Sbjct: 784  ASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV 843

Query: 399  LPRPSSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFST 458
               P+ A   S  TS+   G TP   +P     +A+   S          +   +   + 
Sbjct: 844  SSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR 903

Query: 459  HHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPS 518
              P      S  +   G G        D     ++S       ++     P    +P+ +
Sbjct: 904  SSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSS------EARTLSATPVDTSTPVTT 957

Query: 519  PAAHITTPVPASVLQ-PFSNPSAVYLP--SAPISSRLTS----SYIMTSAMLSNAAFVTS 571
                 ++P  A     P S PS    P  S P+S  L +    S + T+ + SN    TS
Sbjct: 958  STEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTS 1017

Query: 572  PDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
             + S+        P  A   S+  ST    S  +P+       +  P  T    SS+   
Sbjct: 1018 TEASSP-------PPTAEGTSMPTSTPSEGS--TPL-------TRMPVSTTMVASSETST 1061

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSL--------SSPL-SGPHKKNCVLNA 682
            LST   ++ +     P ++ S +SSSS+++  TS+        S+PL S P     V+  
Sbjct: 1062 LSTTPADTST-----PVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVV-- 1114

Query: 683  SSALNSYQAAPPYNSLSVHNSNN-GVSPLSAK------LEPS-GRTSLPGGPADIVRQVG 734
            SS  ++    P   S+ V  S     SP +A+        PS G T L   P      V 
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174

Query: 735  AVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITK 794
            +   +  + P+             +A+    SS P     +E      S+   ++  +T 
Sbjct: 1175 SEANTLSTTPVD--------SKTQVATSTEASSPP---PTAEVTSMPTSTPGERSTPLTS 1223

Query: 795  MPGMNSVHKKNPPSLL--APVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
            MP  ++    +  S L  +PV      T+S +   + + A   S P+S +S G
Sbjct: 1224 MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG 1276



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 77/349 (22%), Positives = 144/349 (41%), Gaps = 26/349 (7%)

Query: 524 TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTA 583
           TTP   ++    S  ++    +A  +S  TS+Y   S  L++    T P  ++ MS  + 
Sbjct: 297 TTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSI 356

Query: 584 FPHVAATL-------SIMDSTFKAPSAVSPIPAVIPSP-SHKPSKTKTSKSSKVKDLSTR 635
            P   +TL       S + +T +A S ++   +   +P ++ P  T    SS   + ST 
Sbjct: 357 TPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASS---EASTT 413

Query: 636 SDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPY 695
           S     +K     +S +SSS +++     + S+P  G      +  +++ + S +A    
Sbjct: 414 STIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEA---- 469

Query: 696 NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADI-VRQVGAVGGSSDSCPLSVPSLALHA 754
                  SN   +P+ +K + +  T     P    V  +     S  S PL+  S++   
Sbjct: 470 -------SNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMP 522

Query: 755 GDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKI-TKMPGMNSVHKKN-PPSLLAP 812
              S AS  + + +  S   +   +  +SS++ +   I T  P   S    N P S    
Sbjct: 523 VASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLV 582

Query: 813 VPDPVNSTSSRQVGKNSSLAL-SQSSPSSISSPGHSRQNTNRTGRIRTL 860
           V    ++TS+     N+ +   S++S SS ++ G S   +  + R  T+
Sbjct: 583 VSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTI 631



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 62/306 (20%), Positives = 115/306 (37%), Gaps = 43/306 (14%)

Query: 554 SSYIMTSAMLSNAAFVTSP---DPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAV 610
           S ++ T +  + A   TS    +P   +S +T  P + +  S + S     S+    P  
Sbjct: 56  SQHVRTGSAANTATGTTSTNVVEPRMYLSCSTN-PEMTSIESSVTSDTPGVSSTRMTPT- 113

Query: 611 IPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRK--PQSSTSSSSSSSSSSLQTSLSS 668
                 + +   TS S+ +   ST    SP+  +    P S+ S  S SS+ +  ++   
Sbjct: 114 ----ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPL 169

Query: 669 P-------LSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTS 721
           P       L+     +  L  S+  +S    P   ++    ++ G +PL         TS
Sbjct: 170 PSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPL---------TS 220

Query: 722 LPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRK 781
           +P     +         SS++  L    + +      +      SS P +   +EG    
Sbjct: 221 MPASTMKV--------ASSEAITLLTTPVEI---STPVTISAQASSSPTT---AEGPSLS 266

Query: 782 NSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVN--STSSRQVGKNSSLALSQSSPS 839
           NS+ S  +  +T+MP    +   +  S L+  P   N    +S +   + + A   S P+
Sbjct: 267 NSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPT 326

Query: 840 SISSPG 845
           S  + G
Sbjct: 327 STYTEG 332


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 182/792 (22%), Positives = 276/792 (34%), Gaps = 125/792 (15%)

Query: 129  SPSPVSPASN---------PRTSLVQVKT---KACLSGHHSASSTSKPFKTPKDNLLTSS 176
            +P PV+ AS+         P TSL  V T      L    S+ ST      P  +  ++S
Sbjct: 3423 TPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAS 3482

Query: 177  SKQHTVFPAKGSRDKP---CVPVPVVSLEKIPN-----LVKADGANVKMNSTTTTAVSAS 228
            +   T  P   +         P+PV SL  +       L+  D ++V     T   V+ +
Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDT 3542

Query: 229  STSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSE 288
            S++S+  +T   +     + +   +P         LP TI     +G   +  P    S 
Sbjct: 3543 SSASTGDTTRLPVTDTSSASTGQATP---------LPVTIPSSSSSG-HTTPLPVTSTSS 3592

Query: 289  REFDPNKHCGVLDPETKKP--CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAK---- 342
                      V  P +      T      T S S   A P        +   H       
Sbjct: 3593 VSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVT 3652

Query: 343  -SREKEVKDKEHL-LTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLP 400
             +      D   L +T T      Q+ P   + L S  +    P   + A S       P
Sbjct: 3653 DASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATP 3712

Query: 401  RPSSANSISS----------STSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESE 450
             P +  S  S          S SS  +GH    PLP  G  L+S  + D   +   D S 
Sbjct: 3713 LPVTIPSSVSTGDTMPLPVTSPSSASTGHAT--PLPVTG--LSSASTGDTTPLPVTDTSS 3768

Query: 451  KLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPP 510
                  ST H  PL      S              D  R  +  +     +S       P
Sbjct: 3769 A-----STRHATPLPVTDTSSASTD----------DTTRLPVTDV-----SSASTGHATP 3808

Query: 511  AADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVT 570
               +   S +   TTP+P +     S+ S  +  S P++SR       +SA   +A  + 
Sbjct: 3809 LPVTSTSSASTGDTTPLPVT---DTSSVSTGHATSLPVTSR-------SSASTGHATPLP 3858

Query: 571  SPDPSALMS-HTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKV 629
              D S++ + H T  P V +T S+  ST  A           P P   PS   T  ++ V
Sbjct: 3859 VTDTSSVSTGHATPLP-VTSTSSV--STGHAT----------PLPVTSPSSASTGHATPV 3905

Query: 630  KDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQ-TSLSSPLSGPHKKNCVLNASSALNS 688
               ST S  S  +    P ++ SS S+  ++ L  TS SS   G      V +ASSA   
Sbjct: 3906 PVTST-SSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTG 3964

Query: 689  YQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVP 748
            +    P  SLS   S    +PL    + S  ++    P  +        G +   P+++P
Sbjct: 3965 HATPLPLTSLS-SVSTGDTTPLPV-TDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIP 4022

Query: 749  SLAL--HAGDLSLASHNAVSS-----LPLSFDKSEGKKRK-----NSSSSSKACKITKMP 796
            S A   H   L +   ++VS+     LP++   S             +SS+     T +P
Sbjct: 4023 SSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLP 4082

Query: 797  GMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQS---------SPSSISSPGHS 847
                V   +  S     P PV S SS   G  + LA+S +         SP  + +PG +
Sbjct: 4083 ----VTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMT 4138

Query: 848  RQNTNRTGRIRT 859
              +    G  RT
Sbjct: 4139 TPSLKTDGGRRT 4150



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 160/764 (20%), Positives = 271/764 (35%), Gaps = 84/764 (10%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGS 188
            +P PV+  S+  T           S   +  +T  P  T   ++ T  +    V  A  +
Sbjct: 1311 TPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPV-TDASSVSTGHTTPLHVTDASSA 1369

Query: 189  RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
                  P+PV SL           ++V    TT   V++ S++S+  +TP L+     + 
Sbjct: 1370 STGQATPLPVTSL-----------SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSAS 1418

Query: 249  SVPPSPEKILNGKGI-------LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLD 301
            +   +P  + +   +       LP TI      G   +  P    S           V D
Sbjct: 1419 TGHATPLPVTDASSVSTDHATSLPVTIPSAASTG-HTTPLPVTDTSSASTGQATSLLVTD 1477

Query: 302  PE-------TKKPCTRSLTCKT------HSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV 348
                     T  P T + +  T      H  S   A  G      +      +      +
Sbjct: 1478 TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL 1537

Query: 349  KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSI 408
                    ST +  P    P  D+   S+G + P P  +  + S    + LP   ++++ 
Sbjct: 1538 PVTSPSSASTGDTTPL---PVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSAS 1594

Query: 409  SSST--------SSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHH 460
               T        SS  +GHT   PLP    D +S  + D   +   + S       ST H
Sbjct: 1595 KGDTTPLPVTSPSSASTGHTT--PLPVT--DTSSASTGDTTPLPVTNASS-----LSTGH 1645

Query: 461  PRPLAFCSFGSRLMGRGYYV-FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSP 519
              PL   S  S   G    +               +    L+S           + + S 
Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSA 1705

Query: 520  AAHITTPVPASVLQPFSNPSAVYLPSAPISSRLT---SSYIMTSAMLSNAAFVT----SP 572
            +    TP+P + L   S      LP    SS  T   S  ++T A  ++    T    + 
Sbjct: 1706 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTD 1765

Query: 573  DPSALMSHTTAFPHVAATLSIMDSTFKAP----SAVSPIPAVIPSPSHKPSKTKTSKSSK 628
              S   +H T  P    + +  D T + P    S+ S   A IP P   PS   T  ++ 
Sbjct: 1766 TSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQA-IPLPVTSPSSASTGDTTP 1824

Query: 629  VKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNS 688
            +  ++  S  S  +    P +  SS+SS  ++SL  + +S +S  H  + ++  +S++++
Sbjct: 1825 L-PVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883

Query: 689  YQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPA---DIVRQVGAVGGSSDSCPL 745
                P    L V ++N+  +  +  L  +  +S+  G A    +     A  G +   P+
Sbjct: 1884 GDTTP----LPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPV 1939

Query: 746  SVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKA--CKITKMPGMNSVHK 803
            + PS A       L   +A SS+P     S      +S S+  A    +T    +++ H 
Sbjct: 1940 TSPSSASSGHTTPLPVTDA-SSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHA 1998

Query: 804  KNPP-------SLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840
               P       S     P PV S SS   G  + L ++ +S +S
Sbjct: 1999 TPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSAS 2042



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 120/518 (23%), Positives = 192/518 (37%), Gaps = 70/518 (13%)

Query: 368  PAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSIS--------SSTSSNHSGH 419
            P  D+   S+G   P P  +  + S    + LP   ++++ +        + TSS  +GH
Sbjct: 1058 PVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGH 1117

Query: 420  TPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYY 479
            T   PLP    D +S  +     +   D S       ST H  PL      S   G+   
Sbjct: 1118 TT--PLPVT--DTSSASTGHATSLPVTDTSS-----VSTGHTTPLHVTDASSASTGQ--- 1165

Query: 480  VFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPS 539
                       A    V    +       P    SP  +   H  TP+  +     S   
Sbjct: 1166 -----------ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH-ATPLLVTDTSSASTGH 1213

Query: 540  AVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFK 599
            A  LP    SS  T         + +AA      P  +   ++A    A +L + D++  
Sbjct: 1214 ATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSV 1273

Query: 600  APSAVSPIPAVIPS--------PSH--KPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS 649
            +    +P+P    S        P H   PS   T  ++ +  +++ S  S  +    P +
Sbjct: 1274 STGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPL-PVTSLSSASTGDTMPLPVT 1332

Query: 650  STSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAP-PYNSLSVHNSNNG-- 706
            S SS+S+  ++ L  + +S +S  H     +  +S+ ++ QA P P  SLS  ++ +   
Sbjct: 1333 SPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP 1392

Query: 707  ---VSPLSAK------LEPSGRTSLPGGPADIVRQVGAVGGSSD---SCPLSVPSLA--- 751
                SP SA       L  +  +S   G A  +    A   S+D   S P+++PS A   
Sbjct: 1393 LPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG 1452

Query: 752  ----LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPP 807
                L   D S AS    +SL L  D S       +     +        +  +H  +P 
Sbjct: 1453 HTTPLPVTDTSSASTGQATSL-LVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPS 1511

Query: 808  SLLA--PVPDPVNSTSSRQVGKNSSLALSQSSPSSISS 843
            S       P PV S SS   G   ++ L  +SPSS S+
Sbjct: 1512 SASTGHATPLPVTSLSSASTG--DTMPLPVTSPSSAST 1547



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 151/768 (19%), Positives = 262/768 (34%), Gaps = 140/768 (18%)

Query: 129  SPSPVSPASNPRTS----LVQVKTKACLSGHH--------SASSTSKPFKTPKDNLLTSS 176
            +P PV+ AS+  T     L    T +  +GH         S++ST    + P  N+ ++S
Sbjct: 2383 TPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSAS 2442

Query: 177  SKQHTVFPAKGSRDKPC---VPVPVVSLEKIPN-----LVKADGANVKMNSTTTTAVSAS 228
            +   T  P   +         P+P      +       L+  D ++V    TT   V++ 
Sbjct: 2443 TGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSP 2502

Query: 229  STSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSE 288
            S++S+  +TP  +     + +   +P  + N   +        H     +++  +     
Sbjct: 2503 SSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHA---- 2558

Query: 289  REFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV 348
                           T  P T +    T    H   +P                      
Sbjct: 2559 ---------------TSLPVTDTSAAST---GHATPLPVTSTSS---------------- 2584

Query: 349  KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSI 408
                    ST +  P    P  D+   S+G + P P   + + S    + LP        
Sbjct: 2585 -------ASTGDTTPL---PVTDTYSASTGQATPLPVTDTSSASTGDTTPLP-------- 2626

Query: 409  SSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCS 468
             + TSS  +GH    PLP       S   +    +     +       ST H  PL    
Sbjct: 2627 VTDTSSASTGHAT--PLPVTNTSSVSTGHATPLHVTSPSSA-------STGHTTPLPVTD 2677

Query: 469  FGSRLMGRGYY--VFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTP 526
              S   G      V D          +S+   H  S +   IP +A S       H TTP
Sbjct: 2678 ASSVSTGHATSLPVTDA---------SSVFTGHATS-LPVTIPSSASS------GH-TTP 2720

Query: 527  VPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPH 586
            +P +     S   A  LP    SS  T          +++       P  L S ++    
Sbjct: 2721 LPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTG 2780

Query: 587  VAATLSIMDSTFKAPSAVSPIPAV----------IPSPSHKPSKTKTSKSSKVKDLSTRS 636
                L + D++  +    +P+P             P P    S   T  ++ +    T S
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDT-S 2839

Query: 637  DESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYN 696
              S  +    P + TSS+S+  ++ L  + +S  S  H  +  +  +S++++  A P + 
Sbjct: 2840 SASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHV 2899

Query: 697  SLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLAL--HA 754
            +     S    +PL    + S  ++    P  +     A  G +   P++  S A   HA
Sbjct: 2900 TSPSSASTGHATPLPV-TDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHA 2958

Query: 755  GDLSLASHNAVSS-----LPLSFDKSEGKKRK-----NSSSSSKACKITKMPGMNSVHKK 804
              L + S ++VS+     LP++   S             +SS+   + T +P    V   
Sbjct: 2959 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALP----VTST 3014

Query: 805  NPPSLLAPVPDPVNSTSSRQVGKN--------SSLALSQSSPSSISSP 844
            +  S     P PV  TSS   G+         SS++   ++P  ++SP
Sbjct: 3015 SSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSP 3062



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 161/764 (21%), Positives = 269/764 (35%), Gaps = 130/764 (17%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLSGHH--------SASSTSKPFKTPKDNLLTSSSKQ 179
            P  SP S ++   T L    T +  +GH         S++ST      P  +  ++S+  
Sbjct: 2130 PVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGH 2189

Query: 180  HTVFPAKGSRDKP---CVPVPVVSLEK------IPNLVKADGANVKMNSTTTTAVSASST 230
             T  P   +         P+PV S         IP LV  D ++      T   V++ S+
Sbjct: 2190 ATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLV-TDTSSASTGQATPLPVTSLSS 2248

Query: 231  SSSAVSTP-PLIKPVLMSK----SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRR 285
            +S+  +TP P+     +S     S+P +    ++     P  +       T ++   +  
Sbjct: 2249 ASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLH-- 2306

Query: 286  LSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSRE 345
            +++       H   L   +    +   T      S   A  G      +  A   +    
Sbjct: 2307 VTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDT 2366

Query: 346  KEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSA 405
              +        S+    P    P  D+   S+G + P P   + + S    + LP    +
Sbjct: 2367 TPLPVTSSSSASSGHTTPL---PVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLS 2423

Query: 406  NSISSST--------SSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFS 457
            ++ +  T        SS  +GH    PLP      AS  + D   + G D S       S
Sbjct: 2424 SASTGDTTRLPVTNVSSASTGHAT--PLPVTSTSSAS--TGDTTPLPGTDTSS-----VS 2474

Query: 458  THHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLP 517
            T H  PL      S   G          D  R  + S                    P  
Sbjct: 2475 TGHTTPLLVTDASSVSTG----------DTTRLPVTS--------------------PSS 2504

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            +   H TTP+P +       PSA    + P+     SS    S   + +  VTSP  SA 
Sbjct: 2505 ASTGH-TTPLPVT-----DTPSASTGDTTPLPVTNASSL---STRHATSLHVTSPS-SAS 2554

Query: 578  MSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSD 637
              H T+ P       + D++  +    +P+P          S   T  ++ +    T S 
Sbjct: 2555 TGHATSLP-------VTDTSAASTGHATPLPVT------STSSASTGDTTPLPVTDTYS- 2600

Query: 638  ESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNS 697
             S       P + TSS+S+  ++ L  + +S  S  H     +  +S++++  A P + +
Sbjct: 2601 ASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVT 2660

Query: 698  LSVHNSNNGVSPL----SAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLA-- 751
                 S    +PL    ++ +     TSLP   A  V       G + S P+++PS A  
Sbjct: 2661 SPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSV-----FTGHATSLPVTIPSSASS 2715

Query: 752  -----LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNP 806
                 L   D S  S    +SLP++   S       S+  +    +T    +++ H    
Sbjct: 2716 GHTTPLPVTDASSVSTGHATSLPVTDASSV------STGHATPLPVTDASSVSTGHATPL 2769

Query: 807  P-------SLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISS 843
            P       S     P PV  TSS   G+ + L +  +S SS+S+
Sbjct: 2770 PLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPV--TSLSSVST 2811



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 120/533 (22%), Positives = 194/533 (36%), Gaps = 64/533 (12%)

Query: 356  TSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLP-RPSSANSIS----- 409
            TS+     + S P  D+   S+G + P P   + + S    ++LP   +S+ SI      
Sbjct: 2822 TSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSL 2881

Query: 410  --SSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFC 467
              + TSS  +GH    PL       AS  +     +   D S       ST H  PL   
Sbjct: 2882 PVTDTSSISTGHAT--PLHVTSPSSAS--TGHATPLPVTDTSSA-----STGHANPLHVT 2932

Query: 468  SFGSRLMGRG--YYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITT 525
            S  S   G      V D        A    V    +       P    SP  +   H TT
Sbjct: 2933 SPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH-TT 2991

Query: 526  PVPASVLQPFSNPSAVYLPSAPISSRLT--------------SSYIMTSAMLSNAAFVTS 571
            P+P +     S   A  LP    SS  T              S+   T   +++ + V++
Sbjct: 2992 PLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 3051

Query: 572  PD--PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAV----------IPSPSHKPS 619
             D  P  + S ++A    A  L + D++  +    +P+P             P P   PS
Sbjct: 3052 GDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS 3111

Query: 620  KTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCV 679
               T  ++ +    T S  S  +    P + TSS+ +  ++SL  + +S  S       +
Sbjct: 3112 SASTGHATSLPVTDT-SSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLL 3170

Query: 680  LNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGS 739
            +  +S++++  A P   + +   S    +PL     PS  ++    P  +        G 
Sbjct: 3171 VTETSSVSTGHATPLLVTDASSASTGHATPLHVT-SPSSASTGDTTPVPVTDTSSVSTGH 3229

Query: 740  SDSCPLSVPSLA-------LHAGDLSLASHNAVSSLPLSFDKSEGKKRK-----NSSSSS 787
            +   P++  S A       L   D+S AS    + LP++   S            S SS+
Sbjct: 3230 ATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSA 3289

Query: 788  KACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840
                 T +P    V   +  S     P PV STSS   G  + L ++ +S +S
Sbjct: 3290 STGHATPLP----VTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSAS 3338



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 132/545 (24%), Positives = 196/545 (35%), Gaps = 96/545 (17%)

Query: 362  LPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTP 421
            +PS +     S L  +G+S      A+P         LP         + TSS  +GH  
Sbjct: 3365 IPSSASTGDTSTLPVTGASSASTGHATP---------LP--------VTDTSSVSTGHA- 3406

Query: 422  EPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVF 481
              PLP     L+S  + D   +   D S       ST    PL   S  S   G      
Sbjct: 3407 -TPLPVT--SLSSVSTGDTTPLPVTDASSA-----STGQATPLPVTSLSSVSTG------ 3452

Query: 482  DRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAV 541
                         ++    +S       P   +   S +   TT +P +     S   A 
Sbjct: 3453 ---------DTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQAT 3503

Query: 542  YLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAAT--LSIMDSTFK 599
             LP   +SS  T     T  ++++A+ V++   + L    T+      T  L + D++  
Sbjct: 3504 PLPVTSLSSVSTGD--TTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSA 3561

Query: 600  APSAVSPIPAVIPSPS---HKPSKTKTSKSS----KVKDLSTRSDESPSNKKRKPQSSTS 652
            +    +P+P  IPS S   H      TS SS     V  L   S  S S     P   TS
Sbjct: 3562 STGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTS 3621

Query: 653  SSSSSS----------SSSLQTSLSSPL---------SGPHKKNCVLNASSALNSYQAAP 693
            +SS+S+          +SS+ T  ++PL         +G      V + SSA        
Sbjct: 3622 TSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPL 3681

Query: 694  PYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLA-- 751
            P  SLS   S    +PL    + S  ++    P  +        G +   P++ PS A  
Sbjct: 3682 PVTSLS-SVSTGDTTPLPV-TDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAST 3739

Query: 752  -----LHAGDLSLASHNAVSSLPLSFDKSEGKKRK------NSSSSSKACKITKMPGMNS 800
                 L    LS AS    + LP++ D S    R         +SS+     T++P    
Sbjct: 3740 GHATPLPVTGLSSASTGDTTPLPVT-DTSSASTRHATPLPVTDTSSASTDDTTRLP---- 3794

Query: 801  VHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS----ISSPGHSRQNTNRTGR 856
            V   +  S     P PV STSS   G  + L ++ +S  S     S P  SR + + TG 
Sbjct: 3795 VTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSAS-TGH 3853

Query: 857  IRTLP 861
               LP
Sbjct: 3854 ATPLP 3858



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 169/784 (21%), Positives = 260/784 (33%), Gaps = 156/784 (19%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGS 188
            +P  V+ AS+  T          LS   +  +T  P  +P     +S+S  HT       
Sbjct: 1903 TPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSP-----SSASSGHTT------ 1951

Query: 189  RDKPCVPVPVVSLEKIP-----NLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKP 243
                  P+PV     +P     +L   D ++V     T   V+ +S+ S+  +TP    P
Sbjct: 1952 ------PLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP---LP 2002

Query: 244  VLMSKSVP-----PSPEKILNGKGILPTT----IDKKHQNGTKNSNKPYRRLSEREFDPN 294
            V  + SV      P P   L+      TT     D    +  +++  P   LS       
Sbjct: 2003 VTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDT 2062

Query: 295  KHCGVLDPETKKP--CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREK----EV 348
                V  P +      T  L     S+S   A         LL+ +  + S        V
Sbjct: 2063 TPLPVTSPSSASTGHATPLLVTDASSVSTGHAT-------SLLVTDASSVSTGHATALHV 2115

Query: 349  KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSI 408
             D   L T     LP  S  +      S+G + P P   + + S    + LP        
Sbjct: 2116 TDASSLSTGDTTPLPVTSPSS-----ASTGDTTPLPVTDTSSVSTGHATSLP-------- 2162

Query: 409  SSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCS 468
             + TSS  +GH    P+     D +S  +     +   D S       ST    PL   S
Sbjct: 2163 VTDTSSASTGHATSLPVT----DTSSASTGHATPLPVTDTSSA-----STGQATPLPVTS 2213

Query: 469  FGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVP 528
              S   G                   ++    +S    +  P   + L S +   TTP+P
Sbjct: 2214 PSSASTGHAI---------------PLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLP 2258

Query: 529  ASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVA 588
             +     S   A  LP   +SS  T          +    VTSP  SA   H T      
Sbjct: 2259 VTDASSVSTGHATSLPVTSLSSVSTGD--------TTPLPVTSPS-SASTGHATP----- 2304

Query: 589  ATLSIMDSTFKAPSAVSPIPAV----------IPSPSHKPSKTKTSKSSKVKDLSTRSDE 638
              L + D++  +    +P+P             P P   PS   T  ++ +      S  
Sbjct: 2305 --LHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVS 2362

Query: 639  SPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSL 698
            +         SS+S+SS  ++    T  SS  +G      V + SSA   +    P   L
Sbjct: 2363 TGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGL 2422

Query: 699  S--------------VHNSNNG-VSPL----SAKLEPSGRTSLPGGPAD----------I 729
            S              V +++ G  +PL    ++       T LPG              +
Sbjct: 2423 SSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLL 2482

Query: 730  VRQVGAVG-GSSDSCPLSVPSLA-------LHAGDLSLASHNAVSSLPLSFDKSEGKKRK 781
            V    +V  G +   P++ PS A       L   D   AS    + LP++   S   +  
Sbjct: 2483 VTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHA 2542

Query: 782  -----NSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQS 836
                  S SS+     T +P    V   +  S     P PV STSS   G  + L ++ +
Sbjct: 2543 TSLHVTSPSSASTGHATSLP----VTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDT 2598

Query: 837  SPSS 840
              +S
Sbjct: 2599 YSAS 2602



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 120/538 (22%), Positives = 192/538 (35%), Gaps = 68/538 (12%)

Query: 355  LTSTREILPSQSGPAQDS--------LLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSAN 406
            ++++ E     S P++DS        LL +S S G  P     A S  P +  P  S A+
Sbjct: 821  ISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEAS 880

Query: 407  SISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQ----FSTHHPR 462
            +    T    S  T     P     ++    +         ++  L  Q    FST  P 
Sbjct: 881  TAGRPTGQ--SSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPT 938

Query: 463  PLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAH 522
            P +  S G        +              S   K   + +     P   +   S +  
Sbjct: 939  PPSITSTGLTSPQTETHTLSP----------SGSGKTFTTALISNATPLPVTYASSASTG 988

Query: 523  ITTPV----PASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALM 578
             TTP+     +SV    + P  V  PS+ +S+  T+   +T     +   VT   P  + 
Sbjct: 989  HTTPLHVTDASSVSTGHATPLPVTSPSS-VSTGHTTPLPVTDTSSESTGHVT---PLPVT 1044

Query: 579  SHTTAFPHVAATLSIMDSTFKAPSAVSPIPAV----------IPSPSHKPSKTKTSKSSK 628
            S ++A    +  L + D++  +   V+P+P             P P    S   T  ++ 
Sbjct: 1045 SFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATS 1104

Query: 629  VKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNS 688
            +    T S  +          ++S+S+  ++S   T  SS  +G      V +ASSA   
Sbjct: 1105 LPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTG 1164

Query: 689  YQAAPPYNSLSVHNSNNG-----VSPLSAK------LEPSGRTSLPGGPADIVRQVGAVG 737
                 P  SLS  ++ +       SP SA       L  +  +S   G A  +    A  
Sbjct: 1165 QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASS 1224

Query: 738  GSSD---SCPLSVPSLA-------LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSS 787
             S+D   S P+++PS A       L   D S AS    +SL L  D S       +    
Sbjct: 1225 VSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSL-LVTDTSSVSTGDTTPLPV 1283

Query: 788  KACKITKMPGMNSVHKKNPPSLLA--PVPDPVNSTSSRQVGKNSSLALSQSSPSSISS 843
             +        +  +H  +P S       P PV S SS   G   ++ L  +SPSS S+
Sbjct: 1284 TSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG--DTMPLPVTSPSSAST 1339



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 82/363 (22%), Positives = 139/363 (38%), Gaps = 44/363 (12%)

Query: 517  PSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVT---SP- 572
            PS  +H TT     +L   ++  A+ + +   SS +  ++  T +  S A   T   SP 
Sbjct: 834  PSRDSH-TTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPT 892

Query: 573  DPSALMSHTTAFPHVAAT-----------LSIMDSTFKAPSAVSPIPAVIPSPSHKPSKT 621
             PSA    T A   +A T           +S+        S V P P  I S      +T
Sbjct: 893  SPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQT 952

Query: 622  KTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLN 681
            +T   S      T +    SN    P +  SS+S+  ++ L  + +S +S  H     + 
Sbjct: 953  ETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVT 1012

Query: 682  ASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSD 741
            + S++++    P   + +   S   V+PL      S  T     P  +     A  G   
Sbjct: 1013 SPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTG-DSTPLPVTDTSSASTGHVT 1071

Query: 742  SCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSV 801
              P++          LS AS    + LP++   S       S+  + +  +T    +++ 
Sbjct: 1072 PLPVT---------SLSSASTGDTTPLPVTDTSSA------STGHATSLPVTDTSSVSTG 1116

Query: 802  HKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSI--SSPGH-SRQNTNRTGRIR 858
            H           P PV  TSS   G  +SL ++ +S  S   ++P H +  ++  TG+  
Sbjct: 1117 H---------TTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQAT 1167

Query: 859  TLP 861
             LP
Sbjct: 1168 PLP 1170



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 154/760 (20%), Positives = 251/760 (33%), Gaps = 110/760 (14%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLSGHHSA--------SSTSKPFKTPKDNLLTSSSKQ 179
            P  SP S ++   T L    T +  +G  +A        +ST      P  +  ++S+ Q
Sbjct: 2978 PVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQ 3037

Query: 180  HTVFPAKGSRDKPC---VPVPVVSLEKIPN-----LVKADGANVKMNSTTTTAVSASSTS 231
             T  P             P+PV S           L+  D ++      T   V++ S+ 
Sbjct: 3038 ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSV 3097

Query: 232  SSAVSTP-PLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSERE 290
            S+  +TP P+  P   S     S          LP T       G   S  P    S   
Sbjct: 3098 STGDTTPLPVTSPSSASTGHATS----------LPVTDTSSASTGDTTS-LPVTDTSSAY 3146

Query: 291  FDPNKHCGVLDPETKKP--CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV 348
                    V D  +      T  L  +T S+S   A P        LL    + +     
Sbjct: 3147 TGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATP--------LLVTDASSASTGHA 3198

Query: 349  KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSI 408
                    S+     +   P  D+   S+G + P P     + S    + LP    +++ 
Sbjct: 3199 TPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSAS 3258

Query: 409  S--------SSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHH 460
            +        ++TSS  +G T   PLP      AS   +    +     +       ST H
Sbjct: 3259 TGQATPLPVTNTSSVSTGDTM--PLPVTSPSSASTGHATPLPVTSTSSA-------STGH 3309

Query: 461  PRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPA 520
              P+   S  S   G                    V    ++      P    SP  +  
Sbjct: 3310 ATPVPVTSTSSASTGH--------------TTPLPVTDTSSASTGDTTPLPVTSPSSAST 3355

Query: 521  AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSH 580
             H TTP+  ++    S      LP    SS  T          +++       P  + S 
Sbjct: 3356 GH-TTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSL 3414

Query: 581  TTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTK---TSKSSKVKDLST--- 634
            ++        L + D++  +    +P+P    S       T    T  SS     +T   
Sbjct: 3415 SSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLP 3474

Query: 635  ---RSDESPSNKKRKPQSSTSSSSSSSSSSLQ-TSLSSPLSGPHKKNCVLNASSALNSYQ 690
                S  S  +  R P + TSS+S+  ++ L  TSLSS  +G      V +ASS    + 
Sbjct: 3475 VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3534

Query: 691  AAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPA-DIVRQVGAVGGSSDSCPLSVPS 749
               P    S  ++ +     + +L  +  +S   G A  +   + +   S  + PL V S
Sbjct: 3535 TPLPVTDTSSASTGD-----TTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTS 3589

Query: 750  LA---------LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNS 800
             +         LH    S AS   V+ LP++   S       S+  +    +T    +++
Sbjct: 3590 TSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSA------STGHATPLLVTDASSVST 3643

Query: 801  VHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840
             H           P PV   SS   G  + L ++ +S +S
Sbjct: 3644 GH---------ATPLPVTDASSASTGDTTPLPVTDTSSAS 3674



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 90/408 (22%), Positives = 145/408 (35%), Gaps = 86/408 (21%)

Query: 514  SPLPSPAAHITTPVPASVLQPF-SNPSAVYLPSAPISSRLTSSYIMTSAMLS-------- 564
            +P P+   H TT  P + LQ   S+  A   PS   S   T +  + ++++S        
Sbjct: 696  APAPTGDGH-TTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQ 754

Query: 565  --NAAFVTSPDPSALMSHTTAFPHVAATLSIMDS-TFKAPSAVSPIPAVIPSPSHKPSKT 621
              +A+  TSPD +A M+HT       A+     S    + S  +      PS S     T
Sbjct: 755  WTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTT 814

Query: 622  KT-SKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSS-----------SSL------- 662
             + S+       +TR   +PS      QS+T   S+S+S           SS+       
Sbjct: 815  PSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHP 874

Query: 663  -------------QTSLSSPLSGPHK------------------KNCVLNASSALNSYQA 691
                         Q+S +SP + P +                   + +  AS A +++  
Sbjct: 875  TLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFST 934

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEPSG-----RTSLPGGPADIVRQVGAVGGSSDSCPLS 746
             PP                +  L PSG      T+L      +     +   +  + PL 
Sbjct: 935  VPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLH 994

Query: 747  VPSLAL----HAGDLSLASHNAVSS-----LPLSFDKSEGKKR-----KNSSSSSKACKI 792
            V   +     HA  L + S ++VS+     LP++   SE           S SS+     
Sbjct: 995  VTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDS 1054

Query: 793  TKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS 840
            T +P    V   +  S     P PV S SS   G  + L ++ +S +S
Sbjct: 1055 TPLP----VTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSAS 1098


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 166/776 (21%), Positives = 289/776 (37%), Gaps = 120/776 (15%)

Query: 159  SSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMN 218
            SST  P  T   +  T+   + T F +  S  K   P P  +      L  +   +   +
Sbjct: 397  SSTGSPHTTLSPSSSTTHEGEPTTFQSWPS-SKDTSPAPSGTTSAFVKL--STTYHSSPS 453

Query: 219  STTTTAVSASSTS--SSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGT 276
            ST TT  SASST+   S  STP    PV  + + PP+  +      +  +T   +    T
Sbjct: 454  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPA--RSATSGHVEESTAYHRSPGST 511

Query: 277  KNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQF-DLL 335
            +  + P    +    + +         TK     +     H+  H          F D  
Sbjct: 512  QTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSS 571

Query: 336  LAEHKAKSREKEVKDKEHLLT------STREILPSQSGPAQDS--------LLGSSGSSG 381
                +++  +      + + T      ST  +L   S P+  S        L GS+   G
Sbjct: 572  TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 631

Query: 382  PEPKVASPAKS--RPPNSVLPRPSSANSISSSTSSNHSG----HTPEPP----LPPVGGD 431
               K  +   S   P  + LP   +++ +S  ++++HS     HT   P    +P +  +
Sbjct: 632  LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 691

Query: 432  LASRLSS----DEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDR 487
              +  SS    D     G+  +  L  +++T H RP    S  + L+             
Sbjct: 692  STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP---GSTETTLLPDNT--------- 739

Query: 488  FRFALNSMVEKHLNSQMWKKIPPAADSPLPS-------------PAAHITTPVPASVLQP 534
                 + ++E  +      + P    SP  S             P++  T P P +    
Sbjct: 740  ---TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 796

Query: 535  FSNPSAVY------LPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALM----SHTTAF 584
            F  PS         +P+  IS+R T+S ++  +      + +SP  +  M    S TT+ 
Sbjct: 797  FVEPSTTSHGSPSSIPTTHISARSTTSGLVEES----TTYHSSPGSTQTMHFPESDTTSG 852

Query: 585  PHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLST---RSDESPS 641
                +T S   +T    SA S   A++  P+   S   ++ ++   D ST   RS+ES +
Sbjct: 853  RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 912

Query: 642  NKKRKPQSST--SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLS 699
            +   +  + T    + S++S  L  S +SP+S    +   L  S+        P  +  S
Sbjct: 913  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST------TTPGLSERS 966

Query: 700  VHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPL----SVPSLALHAG 755
                ++  SP +  L P+  TS   G ++      +  GS+ +       + P L+ H  
Sbjct: 967  TTFHSSPRSP-ATTLSPASTTS--SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH-- 1021

Query: 756  DLSLASHNAVSS-----LPLSFDKSEGKKRKNSSSSSKACKITKM-PGM---------NS 800
              S  SH++  S     LP S   S   +   +S SS     T + PG          ++
Sbjct: 1022 --STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 1079

Query: 801  VHKKNPPSLLAPV-PDPVNST----SSRQVGKNSSLALSQSSPSSISSPGHSRQNT 851
                NP S    + PD   S+    +S +V  ++    +  SP+S +SPG   ++T
Sbjct: 1080 TFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 1135



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 154/732 (21%), Positives = 267/732 (36%), Gaps = 84/732 (11%)

Query: 157 SASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVK 216
           S S+TS     PK + +TS+S + T  P  GS     +     +    P   ++    + 
Sbjct: 241 SHSATSVFVGEPKTSPITSASMETTALP--GSTTTAGLSEKSTTFYSSP---RSPDRTLS 295

Query: 217 MNSTTTTAVSASSTSS-------------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGI 263
              TT++ VS  ST+S              + + P + +    S S+P S +  L+    
Sbjct: 296 PARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTT 355

Query: 264 LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRR 323
            P+++    ++ T +S+  Y + + R  D     G+L+  T    +      T S S   
Sbjct: 356 TPSSLGP--ESTTFHSSPGYTK-TTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSST 412

Query: 324 AVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSG----PAQDSLLGSSGS 379
              G    F    +                 L++T    PS +      A  + LG S  
Sbjct: 413 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 472

Query: 380 SGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSS 438
           S P         + PP +   R +++  +  ST+ + S G T     P       S  S 
Sbjct: 473 STPVHSSPVATATTPPPA---RSATSGHVEESTAYHRSPGSTQTMHFPE--SSTTSGHSE 527

Query: 439 DEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEK 498
           +     G+    K     +T     LA  S+ S L       F         +  S    
Sbjct: 528 ESATFHGSTTHTKSSTPSTT---AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASH 584

Query: 499 HLNSQMWKKIPPAADSP-------LPSP---AAHITTPVPASVLQP-FSNPSAVYL--PS 545
                M   + PA  +P        PSP    +  TT +P S  +P  S  S  +   P 
Sbjct: 585 SSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR 644

Query: 546 APISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVS 605
           +P ++ L +S  MTS+ +S  +  +   P +  +HTTAFP       +   +  + S+  
Sbjct: 645 SPDTTHLPAS--MTSSGVSEESTTSHSRPGS--THTTAFPGSTTMPGLSQESTASHSSPG 700

Query: 606 PIPAVIPSPSHKPSKTKTSKSSKVKDLST-RSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
           P    +       S   T+ SS   + +T  S    +     P ++T+S    +S  + +
Sbjct: 701 PTDTTL-------SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS 753

Query: 665 SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSP--LSAKLEPSGRTSL 722
           S  SP       +  L+ + +      +  ++S           P   SA +EPS  T+ 
Sbjct: 754 STRSP-------HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS--TTS 804

Query: 723 PGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKN 782
            G P+ I      +   S +  L   S   H+   S  + +   S     D + G+  ++
Sbjct: 805 HGSPSSI--PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES-----DTTSGRGEES 857

Query: 783 SSS-SSKACKITKMPGMNSVHKKNP------PSLLAPVPDPVNSTSSRQVGKNSSLALSQ 835
           ++S SS    I+  P   S   + P      P   A    P +ST+S +  ++++   SQ
Sbjct: 858 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 917

Query: 836 SSPSSISSPGHS 847
            +  +I  P  S
Sbjct: 918 DATGTIVLPARS 929



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 167/813 (20%), Positives = 268/813 (32%), Gaps = 126/813 (15%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSK---PFKTPKDNLL--------TSSS 177
            SP   +    P +S    +++   + H S  +T     P ++    LL        +S S
Sbjct: 1971 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030

Query: 178  KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSS----- 232
             + T  P  GS   P +     +    P   ++    +   STT++ VS  ST+S     
Sbjct: 2031 METTALP--GSTTTPGLSEKSTTFHSSP---RSPATTLSPASTTSSGVSEESTTSHSRPG 2085

Query: 233  --------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGILP--TTIDKKHQNGTKNSNKP 282
                     + +TP L +    S S P S +  L     LP  TT     Q  T + + P
Sbjct: 2086 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL-----LPASTTTSGPSQESTTSHSSP 2140

Query: 283  YRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAK 342
                           G  D       T +L+    S +   + PG       L  +    
Sbjct: 2141 ---------------GSTDTALSPGSTTALSFGQESTTFHSS-PG--STHTTLFPDSTTS 2182

Query: 343  SREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLP-- 400
            S   E   + H  T +     S +      L G S +    P       S P  +  P  
Sbjct: 2183 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 2242

Query: 401  -------RPSSANSISSSTSSNHSGHTPEPPL----PPVGGDLASRLSSDEGEMDGADES 449
                    P S  +     SS  SGH+ +  +    P   G   S   S      G   +
Sbjct: 2243 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR-GESTT 2301

Query: 450  EKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMW-KKI 508
             ++    +     P +  + G       +Y   R       +  SM    +  +    + 
Sbjct: 2302 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS-PTTTLSPASMTSLGVGEESTTSRS 2360

Query: 509  PPAADSPLPSPAAHIT-------TPVPASVLQPFSNPSAVY--LPSAPISSRLTSSYIMT 559
             P +     SPA+  T       T V +S   P S  + V+   P+  +     +++   
Sbjct: 2361 QPGSTHSTVSPASTTTPGLSEESTTVYSS--SPGSTETTVFPRTPTTSVRGEEPTTFHSR 2418

Query: 560  SAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPS 619
             A      F      S L   +TAFP   A+           + +       PS S    
Sbjct: 2419 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 2478

Query: 620  KTKTSKSSKVKDL---STRSDESPSNKKRK--PQSSTSSSSSSSSSSLQTSLSSP----- 669
             T +   S    L   ST S  SPS+ +    P S T+ S S  S++  TS  SP     
Sbjct: 2479 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538

Query: 670  -----LSGPHKKNCVLNASSALNSYQAAPPYNS---LSVHNSNNGVSPLSAKLEPSGRTS 721
                  SG  +++   ++        A P   +   LS H++ +  SP S        ++
Sbjct: 2539 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 2598

Query: 722  LPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSS-----LPLSFDKS- 775
               GP+       +  GS+D+      + AL  G  S   H++  S      P S   S 
Sbjct: 2599 TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 2658

Query: 776  --EGKKRKNSSSSSKACKI----TKMPGMN-----------SVHKKNPPSLLAPVPDPVN 818
              E   R +SS+ S    +    +  PG+            S H    P   A  P   +
Sbjct: 2659 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEES 2718

Query: 819  STSSRQVGKNSSLALSQSSPSSISSPGHSRQNT 851
            +T  R  G   +       P+S ++ GHS ++T
Sbjct: 2719 TTYHRSPGSTPTTHF----PASSTTSGHSEKST 2747



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 168/782 (21%), Positives = 270/782 (34%), Gaps = 148/782 (18%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLS--------GHHSASSTSKPFKTPKDNLLTSSSKQ 179
            P+ SP+S  S   T+L    T A LS           S  +T  P  T    +   S+  
Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362

Query: 180  HTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPP 239
            H+     GS      P    S   +P + +   A+     +T T +S  ST++S      
Sbjct: 4363 HS---RPGSMHTTAFP----SSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS------ 4409

Query: 240  LIKPVLMSKSVPPSPEKILNGKGILPTTI--DKKHQNGTKNSNKPYRRLSEREFDPNKHC 297
                     S+ P      +  G   TT+  D    +G   ++ P             H 
Sbjct: 4410 ---------SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV------------HS 4448

Query: 298  GVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTS 357
                P T      S T +  S + + + P  K   D   A     S   E+    H   S
Sbjct: 4449 STGSPHTTLSPAGSTTRQGESTTFQ-SWPNSK---DTTPAPPTTTSAFVELSTTSHGSPS 4504

Query: 358  TREILPSQSGPAQDSLLGSSGSS-----GPEPKVASPAKSRPPNSVLPRPSSANSISSST 412
            +    P+    A  + LG S  S      P     +P+ +R   S L   S+  +  SS 
Sbjct: 4505 ST---PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST--TYHSSP 4559

Query: 413  SSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSR 472
             S  + H PE           S  +S  GE      S       ST H    A  +  + 
Sbjct: 4560 GSTQTMHFPE-----------SNTTSGRGEESTTSHS-------STTHTISSAPSTTSAL 4601

Query: 473  LMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVL 532
            +     Y           +  S    H            +     S A+H +     +++
Sbjct: 4602 VEEPTSY---------HSSPGSTATTHFPDSS-----TTSGRSEESTASHSSQDATGTIV 4647

Query: 533  QPFSNPSAVYL---PSAPISSRLTSSYIM----TSAMLSNAAFVTSPDPSALMSHTTAFP 585
             P  + ++V L    ++PISS    +  +    T+  LS  +      PS+  + TT F 
Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS--TPTTHFS 4705

Query: 586  HVAATLSIMDSTFKAPSAVSPIP-AVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKK 644
              + TL   + +    S  SP+  A  PSP+        S +S + + ST    SP + +
Sbjct: 4706 ASSTTLGRSEESTTVHS--SPVATATTPSPAR-------STTSGLVEESTAYHSSPGSTQ 4756

Query: 645  RK--PQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAP--------- 693
                P+SST+S  S  S +  +S +  +S P      L       SY ++P         
Sbjct: 4757 TMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP--TSYHSSPGSIATTHFP 4814

Query: 694  --------PYNSLSVHNS--NNGVSPLSAKLEPSGRTS-------LPGGPADIVRQVGAV 736
                       S + H+S   NG++PL A    SGR +        PG     +      
Sbjct: 4815 ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT 4874

Query: 737  GGSSDSCPLSVPSLALHAGDLSLAS--HNAVSSLPLS-FDKSEGKKRKNSSSSSKACKIT 793
             G S    +   S       LS AS   +++S  P S + ++E        +S+    ++
Sbjct: 4875 PGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 4934

Query: 794  KMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQ----VGKNSSLALSQSSPSSISSPGHSRQ 849
            +     + H K   +     P  + ++S  Q           ALS  SP+S + PG S +
Sbjct: 4935 Q--ESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992

Query: 850  NT 851
            +T
Sbjct: 4993 ST 4994



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 81/361 (22%), Positives = 141/361 (39%), Gaps = 34/361 (9%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            SP +  TT  P S       P +    S+P S+  T     T+A  S     ++P  S+ 
Sbjct: 1753 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA--SGLLEASTPVHSST 1810

Query: 578  MS-HTTAFPHVAATLSIMDSTFKA-PSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTR 635
             S HTT  P  + T     +TF++ PS+   +PA   + S     + TS  S     +T 
Sbjct: 1811 GSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH 1870

Query: 636  SDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPY 695
               S +   R  +S+T  SS  ++++  +   S  SG  +++   ++S         P  
Sbjct: 1871 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1930

Query: 696  NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAG 755
            ++ S  +  +  S  S     S   S      +      +  GS+ +      S      
Sbjct: 1931 STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 1990

Query: 756  DLSLASHNAVSS-----LPLSFDKSEGKKRKNSSS-SSKACKITKMPGMNSV-------- 801
            + S ASH++  +     LP     S       +S  SS + + T +PG  +         
Sbjct: 1991 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 2050

Query: 802  ----HKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQ-------SSPSSISSPGHSRQN 850
                  ++P + L+P      ST+S  V + S+ + S+       + P S ++PG SR +
Sbjct: 2051 TFHSSPRSPATTLSPA-----STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS 2105

Query: 851  T 851
            T
Sbjct: 2106 T 2106



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 89/406 (21%), Positives = 154/406 (37%), Gaps = 82/406 (20%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAML---SNAAFVTSPDP 574
            SP +  TT +PAS      +  +    S+P S+    S   T+A+     +  F +SP  
Sbjct: 2585 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2644

Query: 575  SALMSHTTAFPHVAATLSIMDSTFKAPSAV-SPIPAVIPSPSHKPSKTKTSKSSKVKDLS 633
            +    HTT FP    +  I++++ +  S+  SP   + P+ S  P     S + +    S
Sbjct: 2645 T----HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAS 2700

Query: 634  TRSDESPSNKKRKP--QSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            T +  SP +    P  +S+T   S  S+ +     SS  SG  +K+ + ++S   +    
Sbjct: 2701 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 2760

Query: 692  APPYNSLSVH--NSNNGVSPLSAKLEP-SGRTSLPG-------------------GPADI 729
            +  +++ S    ++ + +SP S ++    G T+ PG                    PA +
Sbjct: 2761 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 2820

Query: 730  VRQ-VGAVGGSSDSCPLSVPSLALHAGD----LSLASHNAVSSLPLSFDKS--------- 775
                VG    +S S P S  S    A      LS  S    SS P S + +         
Sbjct: 2821 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS 2880

Query: 776  -EGKK----------------RKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVP---- 814
              G++                 ++S++S    + T  PG  +  +   P+ L        
Sbjct: 2881 VRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 2940

Query: 815  ---------------DPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
                            P  ST+S  VG+++   LS SS  + + PG
Sbjct: 2941 STTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 2986



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 165/814 (20%), Positives = 277/814 (34%), Gaps = 163/814 (20%)

Query: 133  VSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLL-------TSSSKQHTVFPA 185
            +SP S   +SL    T    SG  S  +T  P  T    LL       +S+   HT    
Sbjct: 3318 LSPGSTTASSLGPEST-TFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 3376

Query: 186  KGS--------------RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTS 231
             GS                K   P P  +      L  +  ++   +ST TT  SASST+
Sbjct: 3377 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL--STTSHGSPSSTPTTHFSASSTT 3434

Query: 232  SSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSER-- 289
                     +    ++ +  PSP +      +  +T        T+  + P    +    
Sbjct: 3435 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 3494

Query: 290  EFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVK 349
            E     H       +  P T S   +  +  H          F    +    +S E    
Sbjct: 3495 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS-STTSGRSEESTAS 3553

Query: 350  DKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSIS 409
                  T T  +LP++S      LLG S +S     ++S +      + LP  ++   +S
Sbjct: 3554 HSSQDATGTI-VLPARS--TTSVLLGESTTS----PISSGSME---TTALPGSTTTPGLS 3603

Query: 410  SSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSF 469
              +++ HS  +P  P        A+ LS       G  E        +T H RP      
Sbjct: 3604 EKSTTFHS--SPRSP--------ATTLSPASTTSSGVSEES------TTSHSRP------ 3641

Query: 470  GSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPA 529
            GS                      +      +S     +   + +   SP +  TT +PA
Sbjct: 3642 GS----------------------THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 3679

Query: 530  SVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAML---SNAAFVTSPDPSALMSHTTAFPH 586
            S     S+  +    S+  S+    S   T+A+     +  F +SP  +    HTT FP 
Sbjct: 3680 STTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGST----HTTLFPD 3735

Query: 587  VAATLSIMDSTFKAPSAV-SPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKR 645
               +  I++++ +  S+  SP   + P+ S  P     S + +    ST +  SP +   
Sbjct: 3736 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 3795

Query: 646  KP--QSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVH-- 701
             P  +S+T   S  S+ +     SS  SG  +K+ + ++S   +    +  +++ S    
Sbjct: 3796 APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 3855

Query: 702  NSNNGVSPLSAKLEP-SGRTSLPG-------------------GPADIVRQ-VGAVGGSS 740
            ++ + +SP S ++    G T+ PG                    PA +    VG    +S
Sbjct: 3856 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 3915

Query: 741  DSCPLSVPSLALHAGD----LSLASHNAVSSLPLSFDKSEGKKR---------------- 780
             S P S  S    A      LS  S    SS P S + +   +                 
Sbjct: 3916 RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSR 3975

Query: 781  ----------KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVP---------------- 814
                      ++S++S    + T  PG  +  +   P+ L                    
Sbjct: 3976 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 4035

Query: 815  ---DPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
                P  ST+S  VG+++   LS SS  + + PG
Sbjct: 4036 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 4069



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 114/545 (20%), Positives = 192/545 (35%), Gaps = 66/545 (12%)

Query: 358  TREILPSQSGPAQDSLLGSSGSS-----GPEPKVASPAKSRPPNSVLPRPSSANSISSST 412
            ++E   S S P       S GS+     GPE      +      ++LP  ++A+ +  ++
Sbjct: 1744 SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAS 1803

Query: 413  SSNHSGH-TPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGS 471
            +  HS   +P   L P G       ++ +GE                      AF    +
Sbjct: 1804 TPVHSSTGSPHTTLSPAGS------TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELST 1857

Query: 472  RLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASV 531
               G              F+ +S               P A +  PSPA   T+ +    
Sbjct: 1858 TSHGS-----PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 1912

Query: 532  LQPFSNPSAVYLPSAPISSRLT-------SSYIMTSAMLSNAAFVTS---PDPSALMSH- 580
                S+P +      P SS  +       +S+  T+  +S+    TS    +P++  S  
Sbjct: 1913 TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP 1972

Query: 581  ----TTAFPHVAATLS-IMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTR 635
                TT FP  + T     +ST    S  +    V+P+ S        S +S +   S  
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 2032

Query: 636  SDESPSNKKRKPQSSTSSSSSSSSSSLQTSLS--SPLSGPHKKNCVLNASSALNSYQAAP 693
            +   P +      S  S++  SS  S  T+LS  S  S    +    + S   +++  A 
Sbjct: 2033 TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 2092

Query: 694  PYNS----LSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPS 749
            P ++    LS H++ +  SP S        ++   GP+       +  GS+D+      +
Sbjct: 2093 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2152

Query: 750  LALHAGDLSLASHNAVSS-----LPLSFDKS---EGKKRKNSSSSSKACKI----TKMPG 797
             AL  G  S   H++  S      P S   S   E   R +SS+ S    +    +  PG
Sbjct: 2153 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 2212

Query: 798  MN-----------SVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGH 846
            +            S H    P   A  P   ++T  R  G   +       P+S ++ GH
Sbjct: 2213 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF----PASSTTSGH 2268

Query: 847  SRQNT 851
            S ++T
Sbjct: 2269 SEKST 2273



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 92/371 (24%), Positives = 150/371 (40%), Gaps = 54/371 (14%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            SP +  TT  P S       P +    S P S+  T     T+A  S     ++P  S+ 
Sbjct: 3310 SPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTA--SGLLEASTPVHSST 3367

Query: 578  MS-HTTAFPHVAATLSIMDSTFKA-PSAVSPIPAV---------IPSPSH-KPSKTKTSK 625
             S HTT  P  + T     +TF++ P++    PA          + + SH  PS T T+ 
Sbjct: 3368 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH 3427

Query: 626  SSKVKDLSTRSDESPS-NKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASS 684
             S       RS+ES + +      ++T S + S++S L    ++  S P     +    S
Sbjct: 3428 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 3487

Query: 685  ALNS--YQAAPPYNSLSVHNSNNGVSPLSAKL-EPSGRTSLPGGPADIVRQVGAVGGSSD 741
               S   + +   +S + H  ++  S  SA + EP+   S PG  A           SS 
Sbjct: 3488 DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA-----TTHFPDSST 3542

Query: 742  SCPLSVPSLALHA-----GDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKI---T 793
            +   S  S A H+     G + L + +  S L       E      SS S +   +   T
Sbjct: 3543 TSGRSEESTASHSSQDATGTIVLPARSTTSVL-----LGESTTSPISSGSMETTALPGST 3597

Query: 794  KMPGMN----SVHK--KNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQ-------SSPSS 840
              PG++    + H   ++P + L+P      ST+S  V + S+ + S+       + P S
Sbjct: 3598 TTPGLSEKSTTFHSSPRSPATTLSPA-----STTSSGVSEESTTSHSRPGSTHTTAFPDS 3652

Query: 841  ISSPGHSRQNT 851
             ++PG SR +T
Sbjct: 3653 TTTPGLSRHST 3663



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 87/362 (24%), Positives = 146/362 (40%), Gaps = 42/362 (11%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            SP +  TT  P S       P +    S+P S+  T     T+A  S     ++P  S+ 
Sbjct: 4393 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA--SGLLEASTPVHSST 4450

Query: 578  MS-HTTAFPHVAATLSIMDSTFKA-PSAVSPIPAV---------IPSPSH-KPSKTKTSK 625
             S HTT  P  + T     +TF++ P++    PA          + + SH  PS T T+ 
Sbjct: 4451 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH 4510

Query: 626  SSKVKDLSTRSDESPS-NKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASS 684
             S       RS+ES + +      ++T S + S++S L    ++  S P     +    S
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570

Query: 685  ALNS--YQAAPPYNSLSVHNSNNGVSPLSAKL-EPSGRTSLPGGPADIVRQVGAVGGSSD 741
               S   + +   +S + H  ++  S  SA + EP+   S PG  A           SS 
Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA-----TTHFPDSST 4625

Query: 742  SCPLSVPSLALHA-----GDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMP 796
            +   S  S A H+     G + L + +  S L          +   S  SS + + T +P
Sbjct: 4626 TSGRSEESTASHSSQDATGTIVLPARSTTSVLL--------GESTTSPISSGSMETTALP 4677

Query: 797  GMNS---VHKKNPPSLLAPVPDPVN--STSSRQVGKNSSLALSQSSP-SSISSPGHSRQN 850
            G  +   + +K+     +P   P    S SS  +G++       SSP ++ ++P  +R  
Sbjct: 4678 GSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 4737

Query: 851  TN 852
            T+
Sbjct: 4738 TS 4739



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 83/406 (20%), Positives = 152/406 (37%), Gaps = 82/406 (20%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAML---SNAAFVTSPDP 574
            SP +  TT +PAS      +  +    S+  S+    S   T+A+     +  F ++P  
Sbjct: 1028 SPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGS 1087

Query: 575  SALMSHTTAFPHVAATLSIMDSTFKAPSAV-SPIPAVIPSPSHKPSKTKTSKSSKVKDLS 633
            +    HTT FP    +  I++++ +  S+  SP   + P+ S  P     S + +    S
Sbjct: 1088 T----HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 1143

Query: 634  TRSDESPSNKKRKP--QSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            T +  SP +    P  +S+T   S  S+ +     SS  SG  +K+ + ++S   +    
Sbjct: 1144 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 1203

Query: 692  APPYNSLSVH--NSNNGVSPLSAKLEP-SGRTSLPG-------------------GPADI 729
            +  +++ S    ++ + +SP S ++    G T+ PG                    PA +
Sbjct: 1204 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 1263

Query: 730  VRQ-VGAVGGSSDSCPLSVPSLALHAG---------------------DLSLASHNAVSS 767
                VG    +S S P S  S    A                      + ++  H+  +S
Sbjct: 1264 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 1323

Query: 768  L----PLSFDKSEGKKR-----KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVP---- 814
            +    P +F             ++S++S    + T  PG  +  +   P+ L        
Sbjct: 1324 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 1383

Query: 815  ---------------DPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
                            P  ST+S  VG+++   LS SS  + + PG
Sbjct: 1384 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 1429



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 142/637 (22%), Positives = 219/637 (34%), Gaps = 107/637 (16%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSK---PFKTPKDNLL--------TSSS 177
            SP   +    P +S    +++   + H S  +T     P ++    LL        +S S
Sbjct: 888  SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 947

Query: 178  KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSS----- 232
             + T  P  GS   P +     +    P   ++    +   STT++ VS  ST+S     
Sbjct: 948  METTALP--GSTTTPGLSERSTTFHSSP---RSPATTLSPASTTSSGVSEESTTSRSRPG 1002

Query: 233  --------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGILP---TTIDKKHQNGTKNSNK 281
                     + +TP L +    S S P S +  L     LP   TT     ++ T +S+ 
Sbjct: 1003 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL-----LPASTTTSGPSQESTTSHSSS 1057

Query: 282  PYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKA 341
                            G  D       T +L+    S +   + PG       L  +   
Sbjct: 1058 ----------------GSTDTALSPGSTTALSFGQESTTFH-SNPG--STHTTLFPDSTT 1098

Query: 342  KSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPR 401
             S   E   + H  T +     S +      L G S +    P       S P  +  P 
Sbjct: 1099 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP- 1157

Query: 402  PSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHH 460
                  +  ST+ + S G TP    P      AS  +S          SEK     S+  
Sbjct: 1158 ------VEESTTYHRSPGSTPTTHFP------ASSTTSGH--------SEKSTIFHSSPD 1197

Query: 461  PRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPA 520
                   S  S   GRG     R         ++ +     S     +  A+ +   SP 
Sbjct: 1198 ASGTTPSSAHSTTSGRGESTTSRISPG-----STEITTLPGSTTTPGLSEASTTFYSSPR 1252

Query: 521  AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSH 580
            +  TT  PAS+        +    S P S+  T S   T+    +    T    S   + 
Sbjct: 1253 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTE 1312

Query: 581  TTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESP 640
            TT FPH + T S+     + P+     PA     +H    T+ S +S + + ST    SP
Sbjct: 1313 TTVFPH-STTTSVHG---EEPTTFHSRPA----STHTTLFTEDSTTSGLTEESTAFPGSP 1364

Query: 641  -SNKKRKPQSST-------SSSSSSSSSSLQTSLS------SPLSGPHKKNCVLNASSAL 686
             S +   P + T       S++  SSS S  T LS      S L G    + +  +S+  
Sbjct: 1365 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 1424

Query: 687  NSYQAAPPYNSLSVHNSNNGVSPLS--AKLEPSGRTS 721
             +   +P   SLS  ++    SP S  A L P+  TS
Sbjct: 1425 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 138/608 (22%), Positives = 212/608 (34%), Gaps = 89/608 (14%)

Query: 133  VSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDKP 192
            +SPA +  + LV   T + LS   S  +T+ P      +L   S K  T + +  S D  
Sbjct: 2481 LSPARSTTSGLVGESTPSRLSPS-STETTTLPGSPTTPSL---SEKSTTFYTSPRSPDAT 2536

Query: 193  CVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPP 252
              P    S        ++  ++ +  ST TTA   S+T      TP L +    S S P 
Sbjct: 2537 LSPATTTSSGVSE---ESSTSHSQPGSTHTTAFPDSTT------TPGLSRHSTTSHSSPG 2587

Query: 253  SPEKILNGKGILP--TTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTR 310
            S +  L     LP  TT     Q  T + + P               G  D       T 
Sbjct: 2588 STDTTL-----LPASTTTSGPSQESTTSHSSP---------------GSTDTALSPGSTT 2627

Query: 311  SLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGPAQ 370
            +L+    S +   + PG       L  +    S   E   + H  T +     S +    
Sbjct: 2628 ALSFGQESTTFHSS-PG--STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 2684

Query: 371  DSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHS-GHTPEPPLPPVG 429
              L G S +    P       S P  +  P       +  ST+ + S G TP    P   
Sbjct: 2685 PGLQGESTTFQTHPASTHTTPSPPSTATAP-------VEESTTYHRSPGSTPTTHFP--- 2734

Query: 430  GDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFR 489
               AS  +S          SEK     S+         S  S   GRG     R      
Sbjct: 2735 ---ASSTTSGH--------SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG-- 2781

Query: 490  FALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPIS 549
               ++ +     S     +  A+ +   SP +  TT  PAS+        +    S P S
Sbjct: 2782 ---STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2838

Query: 550  SRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPA 609
            +  T S   T+    +    T    S   + TT FP  + T S+     + P+     PA
Sbjct: 2839 THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR-STTTSVRG---EEPTTFHSRPA 2894

Query: 610  VIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRK-----------PQSST---SSSS 655
                 +H    T+ S +S + + ST    SP++ +              +S+T   SS S
Sbjct: 2895 ----STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2950

Query: 656  SSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLS--AK 713
            + ++ S   S +S L G    + +  +S+   +   +P   SLS  ++    SP S  A 
Sbjct: 2951 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 3010

Query: 714  LEPSGRTS 721
            L P+  TS
Sbjct: 3011 LSPATTTS 3018



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 135/637 (21%), Positives = 214/637 (33%), Gaps = 107/637 (16%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSK---PFKTPKDNLL--------TSSS 177
            SP   +    P +S    +++   + H S  +T     P ++    LL        +S S
Sbjct: 3528 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587

Query: 178  KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSS----- 232
             + T  P  GS   P +     +    P   ++    +   STT++ VS  ST+S     
Sbjct: 3588 METTALP--GSTTTPGLSEKSTTFHSSP---RSPATTLSPASTTSSGVSEESTTSHSRPG 3642

Query: 233  --------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGILP---TTIDKKHQNGTKNSNK 281
                     + +TP L +    S S P S +  L     LP   TT     ++ T +S+ 
Sbjct: 3643 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL-----LPASTTTSGSSQESTTSHSSS 3697

Query: 282  PYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKA 341
                            G  D       T +L+    S +   + PG       L  +   
Sbjct: 3698 ----------------GSTDTALSPGSTTALSFGQESTTFHSS-PG--STHTTLFPDSTT 3738

Query: 342  KSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPR 401
             S   E   + H  T +     S +      L G S +    P       S P  +  P 
Sbjct: 3739 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP- 3797

Query: 402  PSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHH 460
                  +  ST+ + S G TP    P      AS  +S          SEK     S+  
Sbjct: 3798 ------VEESTTYHRSPGSTPTTHFP------ASSTTSGH--------SEKSTIFHSSPD 3837

Query: 461  PRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPA 520
                   S  S   GRG     R         ++ +     S     +  A+ +   SP 
Sbjct: 3838 ASGTTPSSAHSTTSGRGESTTSRISPG-----STEITTLPGSTTTPGLSEASTTFYSSPR 3892

Query: 521  AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSH 580
            +  TT  PAS+        +    S P S+  T S   T+    +    T    S   + 
Sbjct: 3893 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 3952

Query: 581  TTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESP 640
            TT FP    T    +      S         P+ +H    T+ S +S + + ST    SP
Sbjct: 3953 TTVFPRSTTTSVRREEPTTFHSR--------PASTHTTLFTEDSTTSGLTEESTAFPGSP 4004

Query: 641  SNKKRK-----------PQSST---SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSAL 686
            ++ +              +S+T   SS S+ +  S   S +S L G    + +  +S+  
Sbjct: 4005 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 4064

Query: 687  NSYQAAPPYNSLSVHNSNNGVSPLS--AKLEPSGRTS 721
             +   +P   SLS  ++    SP S  A L P+  TS
Sbjct: 4065 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 4101



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 87/393 (22%), Positives = 145/393 (36%), Gaps = 62/393 (15%)

Query: 510  PAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLT-------SSYIMTSAM 562
            P A +  PSPA   T+ +        S+P +      P SS  +       +S+  T+  
Sbjct: 4724 PVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783

Query: 563  LSNAAFVTS---PDPSALMSH-----TTAFPHVAATLSIMDSTFKAPSA-----VSPIPA 609
            +S+    TS    +P++  S      TT FP  + T    + +  + S+     ++P+PA
Sbjct: 4784 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 4843

Query: 610  VIPSP-----------SHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS-STSSSSSS 657
               +            S    +T  + ++    LS +S    S+ +   Q+ S +S +SS
Sbjct: 4844 HFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 4903

Query: 658  SSSSLQTSLSSPLSGPH-----KKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSA 712
            S S   TSL S     H             S    ++ + P   S     S   ++  S 
Sbjct: 4904 SISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP--GSTETTLSPGSITTSSF 4961

Query: 713  KLEPSGRTSLPGGPADIVRQVG-AVGGSSD------SCPLSVPSLAL-HAGDLSLASHNA 764
              E +   S PG     V      V G S+      S P S  + A  H+  +S+ S  +
Sbjct: 4962 AQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQS 5021

Query: 765  VSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQ 824
                   F  S G     + +   A   T   G  S    +        P P  ST+S  
Sbjct: 5022 T-----PFPDSPG----FTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 5072

Query: 825  VGKNSSLALSQSS------PSSISSPGHSRQNT 851
            VG+ ++  +S S       P+S S+ G + ++T
Sbjct: 5073 VGEPTTFYISPSPTYTTLFPASSSTSGLTEEST 5105



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 68/323 (21%), Positives = 119/323 (36%), Gaps = 36/323 (11%)

Query: 543  LPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSA---LMSHTTAFPHVAATLSIMDSTFK 599
            LP   I+S L  +   T +   +     +P  S    L   +T F    ++      T  
Sbjct: 4179 LPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSS----SDTTP 4234

Query: 600  APSAVSPIPAVIPSPSH-KPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSS 658
            +P + + +P  + +  H +PS T T+  S       RS+ES         ++  SS  ++
Sbjct: 4235 SPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES---------TTVHSSPGAT 4285

Query: 659  SSSL--QTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEP 716
             ++L    S +S L G    + + + S+   +   +     LS  ++    SP S     
Sbjct: 4286 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 4345

Query: 717  SGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSE 776
            S  ++   G ++      +  GS  +      +        S ASH    S P S D + 
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASH----SSPGSTDTTL 4401

Query: 777  GKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQS 836
                  +SS          P   + H     +    +PD  N+T+S  +  ++ +  S  
Sbjct: 4402 SPGSTTASSLG--------PESTTFHSSPGSTETTLLPD--NTTASGLLEASTPVHSSTG 4451

Query: 837  SPSSISSPGHSRQNTNRTGRIRT 859
            SP +  SP  S   T R G   T
Sbjct: 4452 SPHTTLSPAGS---TTRQGESTT 4471


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 126/549 (22%), Positives = 207/549 (37%), Gaps = 71/549 (12%)

Query: 357  STREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKS--RPPNSVLPRPSSANSISSSTSS 414
            S   +LP +   ++  L     S    P+ A   +S  R P ++  R +S +S   S S+
Sbjct: 2032 SRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091

Query: 415  ------NHSG-HTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFC 467
                  NHSG  TP   L        SR S     +D       L+   S+  P  +   
Sbjct: 2092 TPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQ 2151

Query: 468  SFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQM---WKKIPPAADSPLPSPAAHIT 524
            + GS + G G  + D +         S+ E H  S++      I      P PS +A   
Sbjct: 2152 AGGSMMDGPGPRIPDHQ-------RTSVPENHAQSRIALALTAISLGTARPPPSMSAAGL 2204

Query: 525  TPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAF 584
                + V  P    S    P+A ++SR+ ++   ++A ++ A+  T   P+A+    +  
Sbjct: 2205 AARMSQVPAPVPLMSLRTAPAANLASRIPAA---SAAAMNLASARTPAIPTAVNLADSRT 2261

Query: 585  PHVAATLSIMDS-TFKAPSAVS---PIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESP 640
            P  AA +++    T  APSAV+   P     P+ +   ++T  + ++    LS     +P
Sbjct: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAA----LSLTGSGTP 2317

Query: 641  SNKKRKPQSSTSSSSSSSSSSL---QTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNS 697
                  P SS +  + +S++ +       ++P++    +     A ++L S + AP   +
Sbjct: 2318 PTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAP---A 2374

Query: 698  LSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGD- 756
            LS  N  +   PLSA    SGRTS P       R   +    S       PS +   G  
Sbjct: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434

Query: 757  -----LSLASHNAVSSLPLSFDK------------------SEGKKRKNSSSSSKACKIT 793
                 L  A     S +P +F                    S G     +SS+     + 
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494

Query: 794  KMPGMNSVHK-----------KNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSIS 842
             +P     H            + P +L A  P     +SS     +SS + S SS SS S
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554

Query: 843  SPGHSRQNT 851
            S G S  ++
Sbjct: 2555 SSGSSSSDS 2563



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 78/330 (23%), Positives = 126/330 (38%), Gaps = 43/330 (13%)

Query: 546 APISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVS 605
           AP S R   S    SA  S+ +   S   +A  +HTTA               ++PS  S
Sbjct: 254 APKSRRAHRSTSADSASSSDTSRSRSRSAAA-KTHTTALAG------------RSPSPAS 300

Query: 606 PIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESP---SNKKRKPQSSTSSSSSSSSSSL 662
                  +P  +P  T T + S   + +T+   SP    +K +K +S+T  S S   SS 
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSS-PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSST 359

Query: 663 QTSLSSP---LSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGR 719
                +P   L+  H  +    A++ L+     PP  +    + +    P S +  P   
Sbjct: 360 GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS---PPKSPEKLPQSS 416

Query: 720 TSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKK 779
           +S    P+    +V     SS   P   P+           SH  +SS P S ++S G+ 
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPG---------SHREISSSPTSKNRSHGRA 467

Query: 780 RKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPV---------PDPVNSTSSRQVGKNSS 830
           +++ S S    +        +  K+       P          P    S S+++ G++ S
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527

Query: 831 LALSQSSPSSISSPGHSR-QNTNRTGRIRT 859
               +    S   PG SR +NT R GR R+
Sbjct: 528 -PQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/294 (25%), Positives = 109/294 (37%), Gaps = 39/294 (13%)

Query: 379  SSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL-PPVGGDLASRLS 437
            S    P +   A+SR P S  P  S   S  + + S+  G  P   L PP      S + 
Sbjct: 2394 SGRTSPPLLDRARSRTPPSA-PSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP 2452

Query: 438  SDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVE 497
            S       +D+S  L  Q +     P+A    GS+ +  G                S   
Sbjct: 2453 SAF-----SDQSRCLIAQTT-----PVA----GSQSLSSGAVA----------TTTSSAG 2488

Query: 498  KHLNSQMWKKIPPAADSPLPSPAAHITTPVPASV--LQPFSNPSAVYLPSAPISSRLTSS 555
             H N  +    P    S +  P A      P+++  LQP     +    S+  SS  +SS
Sbjct: 2489 DH-NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547

Query: 556  YIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPS 615
               +S+  S ++   S   S  +    A   V +           P+    +    P P 
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP---------TPAPKEAVREGRP-PE 2597

Query: 616  HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP 669
              P+K K   SS     S+ S  S S+      SS+SSSSSSSSSS  +S  SP
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 87/370 (23%), Positives = 133/370 (35%), Gaps = 74/370 (20%)

Query: 507  KIPPAADSP-------LPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMT 559
            + PP+A S         PSP++ +      S+L P  +      P +P+ S  +      
Sbjct: 2408 RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQ-----PRSPVPSAFSDQSRCL 2462

Query: 560  SAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAP----SAVSPIPAVIPSPS 615
             A  +  A   S    A+ + T++       LS+      AP    S V   PA   + +
Sbjct: 2463 IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV-----PAPGVPHSDVGEPPA--STGA 2515

Query: 616  HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHK 675
             +PS     + +K +  S+ S  S S+      SS+SSSSS SSSS     S P      
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP------ 2569

Query: 676  KNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGA 735
                +    AL    +  P    +V                  R   P  P    R+  +
Sbjct: 2570 ----VQPEVALKRVPSPTPAPKEAV------------------REGRPPEPTPAKRKRRS 2607

Query: 736  VGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKM 795
               SS S               S +S ++ SS   S   S      +SSSSS +      
Sbjct: 2608 SSSSSSSS--------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653

Query: 796  PGMNSVHKKNPPSLLAPVPDPVNSTSSRQ----VGKNSSLALS---QSSPSSISSPGHSR 848
            PG  ++ K  P S   P P    S S R+    +  + SL+ S   +  PS   SP   +
Sbjct: 2654 PGPQALPK--PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711

Query: 849  QNTNRTGRIR 858
             +++  G  R
Sbjct: 2712 SSSSERGSRR 2721



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 63/265 (23%), Positives = 89/265 (33%), Gaps = 34/265 (12%)

Query: 600 APSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSS 659
           AP    P   V  S S +    K  K  K KD   RS+ S   ++RK +SS      S S
Sbjct: 164 APEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK-KSSKKKKHRSES 222

Query: 660 SSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGR 719
            S +    SP     +K+          S    P   S   H S +  S  S+    S  
Sbjct: 223 ESKKRKHRSPTPKSKRKS---KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS 279

Query: 720 TSLPGGPADIVRQVGAVGGSSDS----------CPLSVPSLALHAGDLSLASHNAVSSLP 769
            S     A       A+ G S S           P S P         S  +     S P
Sbjct: 280 RS-----AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334

Query: 770 LSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNS 829
              DK + KK K+++  S +      P  +S   + P    AP P      + R  G   
Sbjct: 335 YE-DKDKDKKEKSATRPSPS------PERSSTGPEPP----APTP----LLAERHGGSPQ 379

Query: 830 SLALSQSSPSSISSPGHSRQNTNRT 854
            LA +  S   ++ P  +    +R+
Sbjct: 380 PLATTPLSQEPVNPPSEASPTRDRS 404



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 60/255 (23%)

Query: 269 DKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHS--LSHRRAVP 326
           DKK +     +  P  R + R    +        +T +  +RS   KTH+  L+ R   P
Sbjct: 242 DKKRKRSRSTTPAPKSRRAHRSTSADS---ASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298

Query: 327 --GRKKQFDLLLAEHKAKSREK---------------EVKDKEHLLTSTREILPSQSG-- 367
             GR+ + D   +E    S ++               E KDK+    S     PS     
Sbjct: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS 358

Query: 368 -----PAQDSLLGSSGSSGPEP--------------KVASPAKSR-PPNSVLPRPSSANS 407
                PA   LL       P+P                ASP + R PP S    P S++S
Sbjct: 359 TGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSS 418

Query: 408 ISSSTS------SNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHP 461
            SS  S      S H+  +PE P P         +SS     + +    K D   S H P
Sbjct: 419 ESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS-HTP 477

Query: 462 RPLAFCSFGSRLMGR 476
                    SR MGR
Sbjct: 478 ---------SRRMGR 483



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 60/263 (22%), Positives = 93/263 (35%), Gaps = 48/263 (18%)

Query: 608  PAVIPSPSHKPSKTKTSKSSKVKD-------LSTRSDESPSNKKRKPQSSTSSSSSSSSS 660
            P V       P ++++  S +VKD         + SD SP  K   P++    S S SSS
Sbjct: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS 1642

Query: 661  SLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRT 720
              +        GP  +      SS+  S    PP +  +   S +   P +    P  R 
Sbjct: 1643 KGR--------GPSPE-----GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689

Query: 721  SLPGGP-----ADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKS 775
            S    P     A + R+  +   S ++   + P    H    S++S       P   +KS
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPETRSRTPPR---HRRSPSVSS-------PEPAEKS 1739

Query: 776  EGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQ 835
               +R+ S+SS +  K T   G             +P P P     SR   +      ++
Sbjct: 1740 RSSRRRRSASSPRT-KTTSRRGR------------SPSPKPRGLQRSRSRSRREKTRTTR 1786

Query: 836  SSPSSISSPGHSRQNTNRTGRIR 858
                S SS   SR+      R R
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSR 1809



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 96/426 (22%), Positives = 157/426 (36%), Gaps = 65/426 (15%)

Query: 267  TIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVP 326
            T  ++ ++G+ +  K   R S+R    N       PE KK  +R  + ++ SLS  R+  
Sbjct: 717  TPQRRGRSGSSSERKNKSRTSQRRSRSNS-----SPEMKK--SRISSRRSRSLSSPRS-- 767

Query: 327  GRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGPAQDSLL----GSSGSSGP 382
                         KAKSR          L+  R +  S   P Q S        SGSS P
Sbjct: 768  -------------KAKSR----------LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804

Query: 383  EPKVASPAK-SRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL----PPVGGDLASRLS 437
            + K  +P + SR  +S  P+  S     + +  +HS  +P P +    PP  G + S  +
Sbjct: 805  KAKSRTPPRRSRSSSSPPPKQKS----KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQA 860

Query: 438  SDEGEMDGADESEKLDCQFSTHHPR-----PLAFCSFGSRLMGRGYYVFDRRWDRFRFAL 492
            +++     +   ++  C  S+  P      P      GS           R+      + 
Sbjct: 861  NEQ-----SVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP 915

Query: 493  NSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLP---SAPIS 549
               V+  ++ +  ++    + SP PS     TTP  +  + P SN  +  LP    +  S
Sbjct: 916  QPKVKAIISPR--QRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSS 973

Query: 550  SRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPA 609
            S  T     T    S++  + SP P  + + T   P ++ + S         S V   P 
Sbjct: 974  SPDTKVKPETPPRQSHSGSI-SPYPK-VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPG 1031

Query: 610  VIPSPSHKPSKTKTSKS---SKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSL 666
             +   +   S T   +S        L  +S  SP ++          S S S S    S 
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 667  SSPLSG 672
            +SP  G
Sbjct: 1092 TSPKGG 1097



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 103/483 (21%), Positives = 162/483 (33%), Gaps = 113/483 (23%)

Query: 213  ANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKH 272
            A V +  + T A  A ++ +SA   P L    L S  VP S  + ++G+   P  +D+  
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGR-TSPPLLDRAR 2406

Query: 273  QNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGR-KKQ 331
                 ++    R  SER   P+   G    ++  P  +           R  VP     Q
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD--------QPRSPVPSAFSDQ 2458

Query: 332  FDLLLAEHKAKSREKEVKDKEHLLTSTRE-------ILPSQSGPAQD--SLLGSSGSSGP 382
               L+A+    +  + +       T++          +P+   P  D      S+G+  P
Sbjct: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518

Query: 383  EPKVA-SPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEG 441
                A  PAK R       R SS++S SSS+SS+ S               +S  SS  G
Sbjct: 2519 SALAALQPAKER-------RSSSSSSSSSSSSSSSSS--------------SSSSSSSSG 2557

Query: 442  EMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLN 501
                  E   L  Q                                              
Sbjct: 2558 SSSSDSEGSSLPVQPEV------------------------------------------- 2574

Query: 502  SQMWKKIPPAADSPLPSPAAHITT-----PVPASVLQ---PFSNPSAVYLPSAPISSRLT 553
                K++P    SP P+P   +       P PA   +     S+ S+    S+  SS  +
Sbjct: 2575 --ALKRVP----SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628

Query: 554  SSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPS----------- 602
            SS   +S+  S+++  +S  PS       A P  A+         ++ S           
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688

Query: 603  ---AVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSD-ESPSNKKRKPQSSTSSSSSSS 658
               + SP+    PSP   P   ++S S +      R D  SPS+K+R+   S       S
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748

Query: 659  SSS 661
            S S
Sbjct: 2749 SRS 2751



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 59/228 (25%), Positives = 89/228 (39%), Gaps = 8/228 (3%)

Query: 619 SKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNC 678
           S+T     S+ + L  R        +R+ +S +SS   + S + Q    S  S   KK+ 
Sbjct: 694 SRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR 753

Query: 679 VLNASSALNSYQAAPPYNSLSVHNSNNGVSPL-SAKLEPSGRTSLPGGPADIVRQVGAVG 737
           + +  S   S   +   + LS+  S +G SP    K +   R S  G      +      
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813

Query: 738 GSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPG 797
            S  S   S P     +   S  SH+  SS P    KS    R+ S +S +A + +  P 
Sbjct: 814 RSRSS---SSPPPKQKSKTPSRQSHS--SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868

Query: 798 MNSVHKKNP-PSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 844
             S  + +P P L +  P   + + S      SS    QS PS  SSP
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS-PSRSSSP 915



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 163/809 (20%), Positives = 283/809 (34%), Gaps = 110/809 (13%)

Query: 128  PSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSS---KQHTVFP 184
            PS    S AS+P       +T +  S   S+        TP  + L+ SS   K     P
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 185  AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
            ++G  +    P P  +L + P       ++ ++N+   T     S S S+V    + +  
Sbjct: 1474 SRGRSECDSSPEPK-ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532

Query: 245  LMSKSVPPSPEKI-----------------LNGKGILPTTIDKKHQNGTKNSNKPYRRLS 287
            L  +S   S +++                  + K    T + ++ ++G+        RLS
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592

Query: 288  EREFDPNKHCGVLD---------------PETKKPCTRSLTCKTHS--LSHRRAVPGRKK 330
             R         V D               PE K P  R+L  ++ S   S  R       
Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGS 1652

Query: 331  QFDLLLAEHKAKSREKEVKDKEHLLTSTREILP-----SQSGP-----AQDSLLGSSGSS 380
                   EH  KSR      +      T+   P     S+S P     A+ S    S SS
Sbjct: 1653 SSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712

Query: 381  GPE------------PKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPPV 428
             PE            P V+SP  +    S   R S+++  + +TS      +P+P     
Sbjct: 1713 SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772

Query: 429  GGDLASR---LSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV-FDRR 484
                + R    ++   +  G+ +S     Q S    R         R  G GY+     R
Sbjct: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR-----RRRGGSGYHSRSPAR 1827

Query: 485  WDRFRFALNSMVEKHLNSQMWKKIPPAADSPLP--------SPAAHITTPVPASVLQPFS 536
             +  R +      +       +K   +  SP P        SPA H  +     ++    
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887

Query: 537  NPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDS 596
            + S     ++P+S R + S   TS     +    SP         T       + S   +
Sbjct: 1888 SRSR----TSPVSRRRSRS--RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT 1941

Query: 597  TFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSN--KKRKPQSSTSSS 654
            T +   + +P      S S  P  T+    S+   ++ R   S ++   +R+ +S TS  
Sbjct: 1942 TRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPV 2001

Query: 655  SSSSSSSLQTSLSSPLSGPHKKNCVLNAS---SALNSYQAAPPYNSLSVHNSNNGVSPLS 711
            +   S S  + ++   S       +   S   + L   + +   + L++   +   +P +
Sbjct: 2002 TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRT 2061

Query: 712  AKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLS------------VPSLALHAGDLSL 759
            A+    G+ SL   P   +R+  A G SSD    +             P +AL++  +S 
Sbjct: 2062 AR----GKRSLTRSP-PAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116

Query: 760  ASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPG--MNSVHKKNPPSLLAPVPDPV 817
             S  ++S  PL   +S G      SS +    + +  G  M+    + P      VP+  
Sbjct: 2117 FSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPE-- 2174

Query: 818  NSTSSRQVGKNSSLALSQS-SPSSISSPG 845
            N   SR     ++++L  +  P S+S+ G
Sbjct: 2175 NHAQSRIALALTAISLGTARPPPSMSAAG 2203



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 37/168 (22%), Positives = 65/168 (38%), Gaps = 19/168 (11%)

Query: 517 PSPA--------AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAF 568
           PSPA        A  + P   S  +P S  +A   PS+P   +       ++        
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA-------- 347

Query: 569 VTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSK 628
            T P PS   S T   P  A T  + +    +P  ++  P +   P + PS+   ++   
Sbjct: 348 -TRPSPSPERSSTGPEPP-APTPLLAERHGGSPQPLATTP-LSQEPVNPPSEASPTRDRS 404

Query: 629 VKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKK 676
                 +  +S S++   P    +  S  +SSS ++   +P  G H++
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 26/173 (15%)

Query: 132  PVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDK 191
            P S  +   ++L  ++         S+SS+S    +   +  +SSS   +   ++GS   
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS-- 2567

Query: 192  PCVPV-PVVSLEKIPNLVKADGANVK--------------------MNSTTTTAVSASST 230
              +PV P V+L+++P+   A    V+                     +S+++++ S+SS+
Sbjct: 2568 --LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625

Query: 231  SSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTID-KKHQNGTKNSNKP 282
            SSS+ S+         S S   SP     G   LP     KK   G + S  P
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 67/264 (25%), Positives = 98/264 (37%), Gaps = 32/264 (12%)

Query: 602  SAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLS------TRSDESPSNKKRKPQSSTSSSS 655
            S  SP P      S  P +   S SS+ K  S      +RS  SP  K++    S  S S
Sbjct: 780  SGSSPCPK---QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS 836

Query: 656  SSS--------SSSLQTSLSSPLSG-----PHKKNCVLNASSALNSYQAAPPYNSLSVHN 702
            SSS        +   Q S++SP +      P +++C   +S         P  +S S  +
Sbjct: 837  SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC-FESSPDPELKSRTPSRHSCSGSS 895

Query: 703  SNNGVSPLSAKLEPSGRTS-LPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLAS 761
                 S    +  PS  +S  P   A I  +  +  GSS   P  V S        S++ 
Sbjct: 896  PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955

Query: 762  HNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNP-PSLLAPVPDPVNST 820
             + V S  L      G     SSS     K    P  +     +P P + A  P   + +
Sbjct: 956  CSNVESRLLPRYSHSG-----SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS 1010

Query: 821  SSRQ--VGKNSSLALSQSSPSSIS 842
             S+     + S  +L QS P S+S
Sbjct: 1011 GSKSPCPQEKSKDSLVQSCPGSLS 1034



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)

Query: 127  RPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTP-KDNLLTSSSKQHTVFPA 185
            R S S  S +S+  +S     + +  SG  S+SS S+    P +  +        T  P 
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSG--SSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 186  KGSRD-KPCVPVPVV--------SLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVS 236
            +  R+ +P  P P          S     +   +  ++   +S+++++ S+SS+SSS+ S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 237  TPPLIKPVLMSKSVPPSPEK 256
            +P   KP   +   P SP+K
Sbjct: 2648 SPSPAKPGPQALPKPASPKK 2667


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 84/361 (23%), Positives = 128/361 (35%), Gaps = 30/361 (8%)

Query: 361 ILPSQSGPAQDSLLGSSGSSGPEPKV-ASPAKSRPPNSVLPRPSSANSISSSTSSNHSGH 419
           ++P Q  PA D+  GS  +  P P+  ASP     P  + P  S A S  S+ SS     
Sbjct: 102 VIPHQKDPALDTN-GSLVAPSPSPEARASPGTPGTPE-LRPTFSPAFSRPSAFSSLAEAS 159

Query: 420 TPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYY 479
            P PP   +        +S EG  D               +  P+   S  +       Y
Sbjct: 160 DPGPPRASLRAK-----TSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMY 214

Query: 480 VFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPS 539
               R       L                 P    P+   A    +PV  +V++  + P 
Sbjct: 215 QMSLRGKASGVGL-----------------PGGSLPIKDLAVDSASPVYQAVIKSQNKPE 257

Query: 540 AVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFK 599
                 A  SS L S      A ++   F+  PD  AL   +T   H     S   +T  
Sbjct: 258 DEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPIEHAPVCTS-QATTPL 316

Query: 600 APSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSS 659
            P++  P  A  PS +  P  T  + ++     +T    SP++  R PQ+S+ S + ++S
Sbjct: 317 LPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPR-PQASSYSPAVAAS 375

Query: 660 SSLQTSLS---SPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEP 716
           S+  T  S    P +   K   V  AS   + YQ  P         +N   +P +    P
Sbjct: 376 SAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAP 435

Query: 717 S 717
           +
Sbjct: 436 A 436



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 44/158 (27%), Positives = 67/158 (42%), Gaps = 14/158 (8%)

Query: 512 ADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSR--LTSSYIMTSAMLSNAAFV 569
           ADSP P  +++  +P  A+   P ++ S    P+AP      +T++ I  S      A  
Sbjct: 358 ADSPRPQASSY--SPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 415

Query: 570 TSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAV-----SPIPAVIPS--PSHKPSKTK 622
            SP P A  S T   P  A   +   +    PS V     SP PA  PS  P++ P+ + 
Sbjct: 416 YSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSV 475

Query: 623 TSKSSKVKDLSTR---SDESPSNKKRKPQSSTSSSSSS 657
                  +  S     +D+S S K    +S+TS S  +
Sbjct: 476 AYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQT 513



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 9/157 (5%)

Query: 517 PSPAAHITTPV-PASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPS 575
           P   +  TTP+ PAS     + P A   PSA      T++     A  S  A  +SP  S
Sbjct: 306 PVCTSQATTPLLPAS-----AQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS 360

Query: 576 ALMSHTTAFPHVAATLSIMDST--FKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVK-DL 632
                ++  P VAA+ +    T   + P+A +P P V+ + S +PS  +   +S      
Sbjct: 361 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP 420

Query: 633 STRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP 669
                 +P      P  + S + + + S + T   SP
Sbjct: 421 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSP 457


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 68/242 (28%), Positives = 104/242 (42%), Gaps = 8/242 (3%)

Query: 613 SPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSG 672
           S S   S +  S SS   D S+ S+ S S+      SS SS+SS SS S  +S SS  S 
Sbjct: 699 SESSDSSDSSDSDSSDSSD-SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757

Query: 673 PHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGV-SPLSAKLEPSGRTSLPGGPADIVR 731
               +   ++S + +S  ++   NS   ++S+N   S  S+    S  +S     +D   
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD--- 814

Query: 732 QVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACK 791
              +   SS+S   S  S +  + + S +S ++ SS     D S      NSS SS +  
Sbjct: 815 --SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 792 ITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISS-PGHSRQN 850
            +     +     N  S  +   D  NS+ S     ++S   S SS SS SS   +S  N
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 851 TN 852
           +N
Sbjct: 933 SN 934



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 66/250 (26%), Positives = 108/250 (43%), Gaps = 13/250 (5%)

Query: 595  DSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSS 654
            DS+ ++ S+ S   +     S+    + +S S++  + S  SD S S+      SS SS 
Sbjct: 854  DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 655  SSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKL 714
            SS SS+S  +S SS  S     +   N+S + +S  ++   +S +  +S+N      +  
Sbjct: 914  SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 715  EPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDK 774
              S  +S     +D          SSDS   S  S + ++ D S +S ++ SS   S D 
Sbjct: 974  SDSSDSSNSSDSSD----------SSDSSDSSDSSDSSNSSDSSDSSDSSDSS--NSSDS 1021

Query: 775  SEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNS-SLAL 833
            S      NSS SS +   +     +     +  S  +   D  +S+ S     +S S   
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 834  SQSSPSSISS 843
            S+SS SS SS
Sbjct: 1082 SESSDSSDSS 1091



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 68/256 (26%), Positives = 103/256 (40%), Gaps = 20/256 (7%)

Query: 613  SPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSST---------------SSSSSS 657
            S S   S +  S SS   D S  SD S S+       S+               SS+SS 
Sbjct: 807  SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 658  SSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPS 717
            SS S  +S SS  S     N   N+S + +S  ++   +S S ++S++  S  S+    S
Sbjct: 867  SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926

Query: 718  GRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEG 777
              +S     +D          SSDS   S  S + ++ D S +S ++ S+   S D S  
Sbjct: 927  SNSSDNSNSSDSSNS----SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982

Query: 778  KKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNST-SSRQVGKNSSLALSQS 836
                +SS SS +   +     +     +  S  +   D  NS+ SS     + S   S S
Sbjct: 983  SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 837  SPSSISSPGHSRQNTN 852
            S SS SS      N++
Sbjct: 1043 SDSSDSSDSSDSSNSS 1058



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 108/493 (21%), Positives = 188/493 (38%), Gaps = 35/493 (7%)

Query: 364  SQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEP 423
            S S  + DS   S+ S   +   +S       ++     +S++S  SS SSN S  +   
Sbjct: 824  SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 424  PLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDR 483
                      S  SS+  + D +D S   D   S++        +               
Sbjct: 884  DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD------------ 931

Query: 484  RWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYL 543
                     NS      NS        +++S   S ++  +    +S     S+ S+   
Sbjct: 932  ---------NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS--DSNSSDSSDSS 980

Query: 544  PSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSA 603
             S+  S    SS    S+  SN++  +    S+  S+++   + + + +  DS+  + S+
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 604  VSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQ 663
             S   +     S   + + +S SS   D S  SD S S+   +   S+ SS+SS SS   
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS--D 1098

Query: 664  TSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSL-SVHNSNNGVSPLSAKLEPSGRTSL 722
            +S SS  S     +   ++S + NS  ++   +S  S  +SN+  S  S++   S  +S 
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158

Query: 723  PGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKN 782
                +D          SSDS   S  S +  + D S +S ++ SS   S D S+     +
Sbjct: 1159 SSDSSD-------SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSD 1209

Query: 783  SSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSIS 842
            SS SS +   +     +     N  S  +   D  +S++S     +S  + S S  +  S
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269

Query: 843  SPGHSRQNTNRTG 855
                   N N  G
Sbjct: 1270 DSQSKSGNGNNNG 1282



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 74/317 (23%), Positives = 126/317 (39%), Gaps = 24/317 (7%)

Query: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595
           S+ S+    S+  S    SS    S+  SN++  +    S+    + +     +  S  D
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 596 STFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSS 655
           S+  + S+ S   +     S   + + +S SS   + S  SD S S+      +S+ S+ 
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787

Query: 656 SSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLE 715
           SS+SS    S               N+S + NS  ++   +S    +SN+  S  S+   
Sbjct: 788 SSNSSDSSDS--------------SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 716 PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKS 775
            S  +S     +D      + G  SDS   S  S +  + D S +S+++ SS     D S
Sbjct: 834 DSSNSSDSSDSSD-----SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS-----DSS 883

Query: 776 EGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQ 835
           +  +  NSS SS +   +     +S +  +            +S SS     + S   S 
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943

Query: 836 SSPSSISSPGHSRQNTN 852
           SS SS SS      N++
Sbjct: 944 SSDSSDSSNSSDSSNSS 960



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 68/266 (25%), Positives = 107/266 (40%), Gaps = 13/266 (4%)

Query: 595 DSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS----- 649
           DS   + S  S   +   S S     + +S SS   D S  SD S S+  +   S     
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 650 STSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNG--V 707
           S+ S S S SS   +S SS  S     +   N+S + +S  ++   +S    NS++    
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 708 SPLSAKLEPSGRT-SLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVS 766
           S  S   E S  + S     +D      +    SDS   S  S + ++ D S +S ++ S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752

Query: 767 SLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVG 826
           S     D S+     NSS SS +   +     ++    N  S  +   D  NS+ S    
Sbjct: 753 S-----DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 827 KNSSLALSQSSPSSISSPGHSRQNTN 852
            +S  + S  S SS SS   +  +++
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSS 833



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 75/306 (24%), Positives = 125/306 (40%), Gaps = 5/306 (1%)

Query: 549  SSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIP 608
            SS   SS    S+  SN++  +    S+  S ++     + +    DS+  + S+ S   
Sbjct: 723  SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782

Query: 609  AVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
            +     S+    + +S SS   + S  SD S S+      SS SS+SS SS S  +S SS
Sbjct: 783  SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842

Query: 669  PL--SGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGP 726
                S     +   N S + NS  ++   +S +  +S++      +        S     
Sbjct: 843  DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902

Query: 727  ADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSS 786
            +D      +   SSDS   S  S + ++ D S +S ++ SS   S D S+     +SS+S
Sbjct: 903  SDSSDSSNS-SDSSDSSNSSDSSESSNSSDNSNSSDSSNSS--DSSDSSDSSNSSDSSNS 959

Query: 787  SKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGH 846
            S +   +     NS    +  +         +S SS     ++S   S SS SS SS   
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 847  SRQNTN 852
               N++
Sbjct: 1020 DSSNSS 1025



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 59/235 (25%), Positives = 92/235 (39%), Gaps = 9/235 (3%)

Query: 620 KTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCV 679
           K+ + K       S  SD S S+       S SS S+SSS S  +   S  S     +  
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598

Query: 680 LNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGS 739
            N+S + +S  ++   +S    +S +  S   ++ + S   S                 S
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSS--KSESDSSDSDSKSDSSDSNSSDSSDNSDS 656

Query: 740 SDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMN 799
           SDS   S  S +  + D S +S ++ SS   S D S+     NSS SS +   +     +
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSS--NSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714

Query: 800 SVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRQNTNRT 854
           S    N  S      D  +S SS     ++S   S SS SS SS      +++ +
Sbjct: 715 SSDSSNSNS-----SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 83/390 (21%), Positives = 141/390 (36%), Gaps = 16/390 (4%)

Query: 343  SREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRP 402
            S   +  D  +   S+     S +  + DS   S  S   +   +S + +   +S     
Sbjct: 909  SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968

Query: 403  SSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEM-DGADESEKLDCQFSTHHP 461
            S +NS  SS SSN S  +             S  SSD  +  D +D S   D   S+   
Sbjct: 969  SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028

Query: 462  RPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAA 521
                                    D    + +S      NS        ++DS   S ++
Sbjct: 1029 NSSDSSDSSDSS------------DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076

Query: 522  HITTPVPASVLQPFSNPS--AVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMS 579
              +    +S     SN S  +    S+  S    SS    S+  SN++  +    S+  S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 580  HTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDES 639
             ++     + +    DS+  + S+ S   +     S     + +S SS   D S  SD S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 640  PSNKKRKPQSSTSSSSSS-SSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSL 698
             S+       S+ SS SS SS S  +S SS  S  ++ +   ++S + +S  ++   +S 
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256

Query: 699  SVHNSNNGVSPLSAKLEPSGRTSLPGGPAD 728
               +S +  +  S     SG  +  G  +D
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDSD 1286


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 69/263 (26%), Positives = 108/263 (41%), Gaps = 27/263 (10%)

Query: 621 TKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP--LSGPHKKNC 678
           T +S SS     S+ S  S S+      SS+SSSSSSSSSS  TS S P  L   HK+  
Sbjct: 148 TSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKP 207

Query: 679 VLNASSALNSY-QAAPPYNSLSVHNS----------NNGVSPLSAKLEPSGRTSLPGGPA 727
             ++    +++ + +  +N  S  +S             + P  A  EP   +  P   +
Sbjct: 208 SKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDS 267

Query: 728 DIVRQVGAVGGSSDSCPLSVPSLA----LHAGDLSLASHNAV-----SSLPLSFDKSEGK 778
           +++       G     P   P ++    L A     +S  A+     S+ PL    S  K
Sbjct: 268 NLLT---ITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324

Query: 779 KRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQV-GKNSSLALSQSS 837
           K+    S  K  K+ K+    S  KK+       + DP +S     +  K+ S   S +S
Sbjct: 325 KQIKDKSHVKMGKV-KIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS 383

Query: 838 PSSISSPGHSRQNTNRTGRIRTL 860
            SS SS   +   T + G +R++
Sbjct: 384 SSSSSSSSFTPSQTRQQGPLRSI 406



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 57/270 (21%), Positives = 105/270 (38%), Gaps = 40/270 (14%)

Query: 218 NSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTK 277
           +S+++++ S+SS+SSS+ S+         S +    P K++      P+   ++H++  K
Sbjct: 160 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFK 219

Query: 278 NSNKPYRR--------------LSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRR 323
             ++ + +              L E +  P        P +K+P   S      S   ++
Sbjct: 220 EPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKK 279

Query: 324 AVPGRKKQFDL--LLAEHKAKSR---------------------EKEVKDKEHLLTSTRE 360
           A   R    D   L A+ + KS                      +K++KDK H+     +
Sbjct: 280 APSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVK 339

Query: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
           I    S   + +L        P         S   +S  P P+S++S SSS+S   S   
Sbjct: 340 IESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSS-SSSSSFTPSQTR 398

Query: 421 PEPPLPPVGGDLASRLSSDEGEMDGADESE 450
            + PL  +  DL S    +E E D  ++++
Sbjct: 399 QQGPLRSIMKDLHS--DDNEEESDEVEDND 426



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 63/284 (22%), Positives = 97/284 (34%), Gaps = 30/284 (10%)

Query: 395 PNSVLPRPSSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDC 454
           PN  +   SS++S SSS+SS+ S  +            +S  SS       +  S     
Sbjct: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSSSSSSSSSSSSST 191

Query: 455 QFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADS 514
            FS  H           +LM        +     + A       H  S       P  + 
Sbjct: 192 SFSKPH-----------KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240

Query: 515 PLPS----PAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVT 570
           PL      P      P P S  +P  + + + + S       +    ++ +   +A    
Sbjct: 241 PLKEEKIVPKMAFKEPKPMS-KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRK 299

Query: 571 SPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVK 630
                AL    ++ P +  T S      K  S V      I S + +  K+       + 
Sbjct: 300 KSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIV 359

Query: 631 DLSTRS-DESPSNKKRKPQSSTSSSSSSSSSSL---QTSLSSPL 670
           D +    +E+ S+K    Q S +SSSSSSSSS    QT    PL
Sbjct: 360 DPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPL 403



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 16/169 (9%)

Query: 207 LVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGILPT 266
           L+KA G     N +  T+ S+SS+SSS+ S+         S S   S     +      T
Sbjct: 135 LLKAGG---DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 191

Query: 267 TIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVP 326
           +  K H+   ++  KP +       D  +H       ++     + + K  S   +   P
Sbjct: 192 SFSKPHKLMKEHKEKPSK-------DSREHKSAFKEPSR---DHNKSSKESSKKPKENKP 241

Query: 327 GRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTR---EILPSQSGPAQDS 372
            ++++    +A  + K   KE K   +LLT T    +  PS+  P  DS
Sbjct: 242 LKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDS 290


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 158/746 (21%), Positives = 272/746 (36%), Gaps = 85/746 (11%)

Query: 157 SASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVK 216
           S S+TS     PK + +TS+S + T  P  GS     +     +    P   ++    + 
Sbjct: 162 SHSATSVFVGEPKTSPITSASMETTALP--GSTTTAGLSEKSTTFYSSP---RSPDRTLS 216

Query: 217 MNSTTTTAVSASSTSS-------------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGI 263
              TT++ VS  ST+S              + + P + +    S S+P S +  L+    
Sbjct: 217 PARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTT 276

Query: 264 LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRR 323
            P+++    ++ T +S+  Y + + R  D     G+L+  T    +      T S +   
Sbjct: 277 TPSSLGP--ESTTFHSSPGYTK-TTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASST 333

Query: 324 AVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSG----PAQDSLLGSSGS 379
              G    F    +                 L++T    PS +      A  + LG S  
Sbjct: 334 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 393

Query: 380 SGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSS 438
           S P         + PP +   R +++  +  ST+ + S G T     P       S  S 
Sbjct: 394 STPVHSSPVATATTPPPA---RSATSGHVEESTAYHRSPGSTQTMHFPE--SSTTSGHSE 448

Query: 439 DEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEK 498
           +     G+    K     +T     LA  S+ S L       F         +  S    
Sbjct: 449 ESATFHGSTTHTKSSTPSTT---AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASH 505

Query: 499 HLNSQMWKKIPPAADSP-------LPSP---AAHITTPVPASVLQP-FSNPSAVYL--PS 545
                M   + PA  +P        PSP    +  TT +P S  +P  S  S  +   P 
Sbjct: 506 SSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR 565

Query: 546 APISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVS 605
           +P ++ L +S  MTS+ +S  +  +   P +  +HTTAFP       +   +  + S+  
Sbjct: 566 SPDTTHLPAS--MTSSGVSEESTTSHSRPGS--THTTAFPGSTTMPGLSQESTASHSSPG 621

Query: 606 PIPAVIPSPSHKPSKTKTSKSSKVKDLST-RSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
           P    +       S   T+ SS   + +T  S    +     P ++T+S    +S  + +
Sbjct: 622 PTDTTL-------SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS 674

Query: 665 SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSP--LSAKLEPSGRTSL 722
           S  SP       +  L+ + +      +  ++S    N      P   SA +EPS  T+ 
Sbjct: 675 STRSP-------HTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPS--TTS 725

Query: 723 PGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKN 782
            G P+ I      +   S +  L   S   H+   S  + +   S     D + G+  ++
Sbjct: 726 HGSPSSI--PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES-----DTTSGRGEES 778

Query: 783 SSS-SSKACKITKMPGMNSVHKKNP------PSLLAPVPDPVNSTSSRQVGKNSSLALSQ 835
           ++S SS    I+  P   S   + P      P   A    P +ST+S +  ++ +   SQ
Sbjct: 779 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQ 838

Query: 836 SSPSSISSPGHSRQNTNRTGRIRTLP 861
            +  +I  P  S  N+   G   T P
Sbjct: 839 DATGTIVLPARS-TNSVLLGESTTSP 863



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 87/373 (23%), Positives = 141/373 (37%), Gaps = 53/373 (14%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFV---TSPDP 574
            S   H +T  P + L P  + +     S    S  +S   M +   + +AFV   T+   
Sbjct: 1110 STPVHSSTGSPRTTLSPAGSTTRQG-ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG 1168

Query: 575  SALMSHTTAFPHVAATLSIMDSTFKAPSAVSPI-PAVIPSPSHKPSKTKTSKSSKVKDLS 633
            S     TT F   + T    + +    S  SP+ PA  PSP+        S +S + + S
Sbjct: 1169 SPSSIPTTHFSASSTTFGRSEESTTVHS--SPVAPATTPSPAR-------STTSGLVEES 1219

Query: 634  TRSDESPSNKKRK--PQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            T    SP + +    P+SST+S  S  S +  +S +  +S P      L       SY +
Sbjct: 1220 TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP--TSYHS 1277

Query: 692  AP-----------------PYNSLSVHNS--NNGVSPLSAKLEPSGRTS-------LPGG 725
            +P                    S + H+S   NG++PL A    SGR +        PG 
Sbjct: 1278 SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGS 1337

Query: 726  PADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLAS--HNAVSSLPLS-FDKSEGKKRKN 782
                +       G S    +   S       LS AS   +++S  P S + ++E      
Sbjct: 1338 METTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTA 1397

Query: 783  SSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQ----VGKNSSLALSQSSP 838
              +S+    +++     + H K   +     P  + ++S  Q           ALS  SP
Sbjct: 1398 FPASTTTSGLSQ--ESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSP 1455

Query: 839  SSISSPGHSRQNT 851
            +S + PG S ++T
Sbjct: 1456 ASTTVPGLSEEST 1468



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 85/360 (23%), Positives = 135/360 (37%), Gaps = 60/360 (16%)

Query: 518 SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
           SP    TT  P S       P      S P S+  T     T+A  S     + P  S+ 
Sbjct: 619 SPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTA--SGLLEASMPVHSST 676

Query: 578 MS-HTTAFPHVAATLSIMDSTFKA-PSA--VSPIPAVIPSPSHKPSKTKTSKSSKVKDLS 633
            S HTT  P  + T     +TF + PS+    P P    S   +PS T     S +   +
Sbjct: 677 RSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIP--T 734

Query: 634 TRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAP 693
           T      +      +S+T  SS  S+ ++    S   SG  +++   + SS  ++  +AP
Sbjct: 735 THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES-TTSHSSTTHTISSAP 793

Query: 694 PYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALH 753
              S  V              EP+   S PG  A           SS +   S  S+A H
Sbjct: 794 STTSALVE-------------EPTSYHSSPGSTA-----TTHFPDSSTTSGRSEESIASH 835

Query: 754 AGDLSLASHNAVSSLPLSFDKSEG---KKRKNSSSSSKACKITKMPGMNSV--------- 801
                 +S +A  ++ L    +      +   S  SS + + T +PG  +          
Sbjct: 836 ------SSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 889

Query: 802 ---HKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQ-------SSPSSISSPGHSRQNT 851
                ++P + L+P      ST+S  V + S+ + S+       + P S ++PG SR +T
Sbjct: 890 FHSSPRSPATTLSPA-----STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 944



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 87/393 (22%), Positives = 145/393 (36%), Gaps = 62/393 (15%)

Query: 510  PAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLT-------SSYIMTSAM 562
            P A +  PSPA   T+ +        S+P +      P SS  +       +S+  T+  
Sbjct: 1198 PVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 1257

Query: 563  LSNAAFVTS---PDPSALMSH-----TTAFPHVAATLSIMDSTFKAPSA-----VSPIPA 609
            +S+    TS    +P++  S      TT FP  + T    + +  + S+     ++P+PA
Sbjct: 1258 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 1317

Query: 610  VIPSP-----------SHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQS-STSSSSSS 657
               +            S    +T  + ++    LS +S    S+ +   Q+ S +S +SS
Sbjct: 1318 HFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 1377

Query: 658  SSSSLQTSLSSPLSGPH-----KKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSA 712
            S S   TSL S     H             S    ++ + P   S     S   ++  S 
Sbjct: 1378 SISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP--GSTETTLSPGSITTSSF 1435

Query: 713  KLEPSGRTSLPGGPADIVRQVG-AVGGSSD------SCPLSVPSLAL-HAGDLSLASHNA 764
              E +   S PG     V      V G S+      S P S  + A  H+  +S+ S  +
Sbjct: 1436 AQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQS 1495

Query: 765  VSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQ 824
                   F  S G     + +   A   T   G  S    +        P P  ST+S  
Sbjct: 1496 T-----PFPDSPG----FTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 1546

Query: 825  VGKNSSLALSQSS------PSSISSPGHSRQNT 851
            VG+ ++  +S S       P+S S+ G + ++T
Sbjct: 1547 VGEPTTFYISPSPTYTTLFPASSSTSGLTEEST 1579


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 157/746 (21%), Positives = 272/746 (36%), Gaps = 85/746 (11%)

Query: 157 SASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVK 216
           S S+TS     PK + +TS+S + T  P  GS     +     +    P   ++    + 
Sbjct: 97  SHSATSVFVGEPKTSPITSASMETTALP--GSTTTAGLSEKSTTFYSSP---RSPDRTLS 151

Query: 217 MNSTTTTAVSASSTSS-------------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGI 263
              TT++ VS  ST+S              + + P + +    S S+P S +  L+    
Sbjct: 152 PARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTT 211

Query: 264 LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRR 323
            P+++    ++ T +S+  Y + + R  D     G+L+  T    +      T S S   
Sbjct: 212 TPSSLGP--ESTTFHSSPGYTK-TTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSST 268

Query: 324 AVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSG----PAQDSLLGSSGS 379
              G    F    +                 L++T    PS +      A  + LG S  
Sbjct: 269 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 328

Query: 380 SGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSS 438
           S P         + PP +   R +++  +  ST+ + S G T     P       S  S 
Sbjct: 329 STPVHSSPVATATTPPPA---RSATSGHVEESTAYHRSPGSTQTMHFPE--SSTTSGHSE 383

Query: 439 DEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEK 498
           +     G+    K     +T     LA  S+ S L       F         +  S    
Sbjct: 384 ESATFHGSTTHTKSSTPSTT---AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASH 440

Query: 499 HLNSQMWKKIPPAADSP-------LPSP---AAHITTPVPASVLQP-FSNPSAVYL--PS 545
                M   + PA  +P        PSP    +  TT +P S  +P  S  S  +   P 
Sbjct: 441 SSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR 500

Query: 546 APISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVS 605
           +P ++ L +   MTS+ +S  +  +   P +  +HTTAFP       +   +  + S+  
Sbjct: 501 SPDTTHLPAR--MTSSGVSEESTTSHSRPGS--THTTAFPGSTTMPGLSQESTASHSSPG 556

Query: 606 PIPAVIPSPSHKPSKTKTSKSSKVKDLST-RSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
           P    +       S   T+ SS   + +T  S    +     P ++T+S    +S+ + +
Sbjct: 557 PTDTTL-------SPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHS 609

Query: 665 SLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSP--LSAKLEPSGRTSL 722
           S  SP       +  L+ + +      +  ++S           P   SA +EPS  T+ 
Sbjct: 610 STRSP-------HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS--TTS 660

Query: 723 PGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKN 782
            G P+ I      +   S +  L   S   H+   S  + +   S     D + G+  ++
Sbjct: 661 HGSPSSI--PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES-----DTTSGRGEES 713

Query: 783 SSS-SSKACKITKMPGMNSVHKKNP------PSLLAPVPDPVNSTSSRQVGKNSSLALSQ 835
           ++S SS    I+  P   S   + P      P   A    P +ST+S +  ++++   SQ
Sbjct: 714 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 773

Query: 836 SSPSSISSPGHSRQNTNRTGRIRTLP 861
            +  +I  P  S  N+   G   T P
Sbjct: 774 DATGTIVLPARS-TNSVLLGESTTSP 798



 Score = 33.5 bits (75), Expect = 0.87
 Identities = 71/339 (20%), Positives = 119/339 (35%), Gaps = 19/339 (5%)

Query: 519 PAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVT------SP 572
           P +  TT  P S   P  +  +    S+P  +  T S   T+A      + T      S 
Sbjct: 527 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGST 586

Query: 573 DPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDL 632
           + + L  +TTA   + A+  +  ST       SP   + P+ S       T+  S     
Sbjct: 587 ETTLLPDNTTASGLLEASTPVHSST------RSPHTTLSPAGSTTRQGESTTFHSWPSSK 640

Query: 633 STRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAA 692
            TR     +       S+TS  S SS  +   S  S  SG  +++   ++S         
Sbjct: 641 DTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHF 700

Query: 693 PPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLAL 752
           P  ++ S     +  S  S     S   S      +      +  GS+ +      S   
Sbjct: 701 PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 760

Query: 753 HAGDLSLASHNAVSS-----LPLSFDKSEGKKRKNSSS-SSKACKITKMPGMNSVHKKNP 806
              + S ASH++  +     LP     S       +S  SS + + T +PG  +    + 
Sbjct: 761 GRSEESTASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 820

Query: 807 PSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
            S       P +  ++      +S  +S+ S +S S PG
Sbjct: 821 RSTTFH-SSPRSPATTLSPASTTSSGVSEESTTSHSRPG 858


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 71/354 (20%), Positives = 138/354 (38%), Gaps = 30/354 (8%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ +   ++  T++   ++A  S+    T+P P  L S  T 
Sbjct: 4703 STPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG-TAPPPKVLTSPATT 4761

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A TL ++ ST    +A S    V P PS     T T        
Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATS----VTPIPSSTLGTTGTLPEQTTTP 4817

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            ++T S   PS+      +ST  ++ ++++   +S S+P S P     +   ++A  +  A
Sbjct: 4818 VATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAA 4877

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGG----PADIVRQVGAVGGSSDSCPLSV 747
              P    +  +S  G + +  +L  +  T+   G    P+        +   S +  ++V
Sbjct: 4878 TGP---TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV 4934

Query: 748  P--SLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKN 805
            P  S A  +   + A    VS+   +   +  K   +SS  +     T +P + S     
Sbjct: 4935 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGT----ATALPALRSTATTP 4990

Query: 806  PPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRQNTNRTGRIRT 859
              +    +P     T+  ++ + ++   + S+ +  S+P     +T  T    T
Sbjct: 4991 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATT 5044



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 72/364 (19%), Positives = 136/364 (37%), Gaps = 55/364 (15%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ + P ++  T++   ++A    +   T+P P  L +  T 
Sbjct: 2580 STPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTAT-PTSTLRTAPPPKVLTTTATT 2638

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A  L  + ST   P+A S    V P PS     T T  S     
Sbjct: 2639 PTVTSSKATPSSSPGTATALPALRSTATTPTATS----VTPIPSSSLGTTWTRLSQTTTP 2694

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
             +T S  +PS+      +ST  +++++++    S+++P S P   +     ++    + A
Sbjct: 2695 TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2754

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEP--SGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPS 749
             P              SP +A   P     T+ P      V      G +  +  L+  +
Sbjct: 2755 TP------------SSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2802

Query: 750  LALHAGDLSLASHNAVSS-------LPLSFDKSEGKKRKNSSSSSKACKITKMPG--MNS 800
              +  G ++  S +  +S       +P +   + G+    SS  +     T      + +
Sbjct: 2803 TTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2862

Query: 801  VHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSS----------ISSPGHSRQN 850
             H   P ++ +        T+     ++S+ ALS   PSS           ++PGH+   
Sbjct: 2863 THITEPSTVTSHTLAATTGTT-----QHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT 2917

Query: 851  TNRT 854
            +  T
Sbjct: 2918 SRTT 2921



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 68/357 (19%), Positives = 134/357 (37%), Gaps = 55/357 (15%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ +   ++  T++   ++A+ S+    T+P P  L S  T 
Sbjct: 3556 STPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG-TAPPPKVLTSTATT 3614

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A TL ++ ST    +A S      P PS     T T        
Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATS----FTPIPSFTLGTTGTLPEQTTTP 3670

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            ++T S   PS+      +ST  ++ ++++   +S+S+P S P     +   ++A  +  A
Sbjct: 3671 MATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA 3730

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLA 751
              P    +  +S  G + +  +   +   ++P G                    +  S  
Sbjct: 3731 TGP---TATPSSTPGTTWILTEPSTTATVTVPTGST-----------------ATASSTR 3770

Query: 752  LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLA 811
              AG L + +  A +   +S           ++ SS     T +P + S       + + 
Sbjct: 3771 ATAGTLKVLTSTATTPTVIS---------SRATPSSSPGTATALPALRSTATTPTATSVT 3821

Query: 812  PVPDPVNSTSSRQVGKNS--SLALSQSSPSSISSPGH-------SRQNTNRTGRIRT 859
             +P     T+  ++ + +  +  +S ++PSS     H       +   T  TG + T
Sbjct: 3822 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVAT 3878



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 47/194 (24%), Positives = 77/194 (39%), Gaps = 35/194 (18%)

Query: 510  PAADSPLPSPAAHITTPVPASVL-------QPFSNPSAVYLPSAPISSRLTS--SYIMTS 560
            PA  S   +P A   TP+P+S L          + P+A    + P S+  T+  S ++T+
Sbjct: 2659 PALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTA 2718

Query: 561  AMLSNAAF--VTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKP 618
               +  A   V +P  +   +HTT  P    T       F A  + SP  A+ P      
Sbjct: 2719 TATTTGATGSVATPSSTPGTAHTTKVPTTTTT------GFTATPSSSPGTALTPPVWIST 2772

Query: 619  SKTKTSKSSKVKD------------LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSL 666
            + T T++ S V              L+T +    +     P SST +S ++ +  +  ++
Sbjct: 2773 TTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTM 2832

Query: 667  ------SSPLSGPH 674
                  S P S PH
Sbjct: 2833 ATTHGRSLPPSSPH 2846



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 135/680 (19%), Positives = 218/680 (32%), Gaps = 106/680 (15%)

Query: 145  QVKTKACLSGH----HSASSTSKPFKTPKDN-LLTSSSKQHTVFPAKGSRDKPCVPVPVV 199
            +++   C  GH     + SST+ P  TP    +LT  +   T     GS     +P    
Sbjct: 3543 EIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGST---AIPSSTP 3599

Query: 200  SLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK-------SVPP 252
                 P ++ +        +TT TA S+ +TSSS+  T   + PVL S        S  P
Sbjct: 3600 GTAPPPKVLTS-------TATTPTATSSKATSSSSPRTATTL-PVLTSTATKSTATSFTP 3651

Query: 253  SPEKILNGKGILP-------TTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETK 305
             P   L   G LP        T+   H + T  +      L+ +         +  P + 
Sbjct: 3652 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSST 3711

Query: 306  KPCTRSLT-----CKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE 360
               T  LT       T + +   A P        +L E    +            +STR 
Sbjct: 3712 PGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRA 3771

Query: 361  ILPS----QSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNH 416
               +     S     +++ S  +    P  A+   +    +  P  +S  +I SS+    
Sbjct: 3772 TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3831

Query: 417  SGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGR 476
                 +   P      A+  S+ E                + H    L   +  +R  G 
Sbjct: 3832 WTRLSQTTTPTATMSTATPSSTPE----------------TVHTSTVLTTTTTTTRATGS 3875

Query: 477  GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADS-----PLPSPAAHITTPVPASV 531
                          A  S      ++    K+P    +     P  SP   +T PV  S 
Sbjct: 3876 -------------VATPSSTPGTAHTT---KVPTTTTTGFTATPSSSPGTALTPPVWIST 3919

Query: 532  LQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATL 591
                +   +   PS+   +  T++ + T+        + +P  S   S TT  P V  T 
Sbjct: 3920 TTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTT 3979

Query: 592  SIMDSTFKAPSAVSPIPAV-------------IPSPSHKPSKTKTSKSSKVKDLSTRSDE 638
            +        PS+   +                I  PS   S T  + +S  +  ST +  
Sbjct: 3980 ATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQH-STPALS 4038

Query: 639  SPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSL 698
            SP    R  +S  S  +++   +  TS ++  + P K       S+ L S   + P  ++
Sbjct: 4039 SPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSK----TRTSTLLPSSPTSAPITTV 4094

Query: 699  SVHNSNNGVSPLSAKLE------PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLAL 752
                   G  P  A  E      P    S  GG  D    + A GG+    PL +   A 
Sbjct: 4095 ----VTTGCEPQCAWSEWLDYSYPMPGPS--GGDFDTYSNIRAAGGAVCEQPLGLECRAQ 4148

Query: 753  HAGDLSLASHNAVSSLPLSF 772
                + L     V    L F
Sbjct: 4149 AQPGVPLRELGQVVECSLDF 4168



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 60/279 (21%), Positives = 102/279 (36%), Gaps = 39/279 (13%)

Query: 510  PAADSPLPSPAAHITTPVPASVL-------QPFSNPSAVYLPSAPISS---RLTSSYIMT 559
            PA  S   +P A   T +P+S L          + P+A    + P S+     TS+ + T
Sbjct: 4308 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTT 4367

Query: 560  SAMLSNAA-FVTSPDPSALMSHTTAFPHVAAT-----------------LSIMDSTFKAP 601
            +A  + A   V +P  +   +HTT  P    T                 + I  +T    
Sbjct: 4368 TATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTT 4427

Query: 602  SAVSPIPAVIPSPSHKP---SKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTS------ 652
            S  +  P+ +P  +H P   + T T+ ++      + S ++       P  +T+      
Sbjct: 4428 SGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGR 4487

Query: 653  SSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSA 712
            S S SS  +++T+ +S  SG      +   S+  +   AA    +     + +   P S 
Sbjct: 4488 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 4547

Query: 713  KLE--PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPS 749
              E  PS  T+ PG      R       S       +PS
Sbjct: 4548 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 4586



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 65/289 (22%), Positives = 118/289 (40%), Gaps = 33/289 (11%)

Query: 510  PAADSPLPSPAAHITTPVPASVL-QPFSNPSAVYLPSAPISSRLTSSY---IMTSAMLSN 565
            PA  S   +P A   T +P+S L   ++  S    P+A +S+   SS    + TS +L+ 
Sbjct: 4981 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTA 5040

Query: 566  AAFVT-------SPDPSALMSHTTAFPHV-----AATLSIMDSTFKAPSAVSPIPAVIPS 613
             A  T       +P  +   +HTT  P        AT S    T   P   +P+  +  S
Sbjct: 5041 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTM--S 5098

Query: 614  PSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSS------SSSSSSSLQTSLS 667
              H  S  +T+ +S V   +T +    +N    P S+  ++      +++++++  T  +
Sbjct: 5099 TIHTSSTPETTHTSTVL-TTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGST 5157

Query: 668  SPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPA 727
            + LS       +L   S + +     P  S +  +S  G +     +  +   ++P   A
Sbjct: 5158 ATLSSTPGTTWILTEPSTIATVMV--PTGSTATASSTLGTAHTPKVV--TTMATMPTATA 5213

Query: 728  DIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSL-PLSFDKS 775
              V     VG  +   P  +PS +L    +S  S + +++L P  F  S
Sbjct: 5214 STVPSSSTVG--TTRTPAVLPS-SLPTFSVSTVSSSVLTTLRPTGFPSS 5259



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 60/278 (21%), Positives = 96/278 (34%), Gaps = 30/278 (10%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P  SP   +T PV  S     +   +   PS+   +  T++ + T+        + +P 
Sbjct: 2755 TPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPS 2814

Query: 574  PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAV-------------IPSPSHKPSK 620
             S   S TT  P V  T++        PS+   +                I  PS   S 
Sbjct: 2815 SSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 2874

Query: 621  TKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVL 680
            T  + +   +  ST +  SP    R  +S  S  +++   +  TS ++  + P K     
Sbjct: 2875 TLAATTGTTQH-STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK----T 2929

Query: 681  NASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLE------PSGRTSLPGGPADIVRQVG 734
              S+ L S   + P  ++       G  P  A  E      P    S  GG  D    + 
Sbjct: 2930 RTSTLLPSSPTSAPITTV----VTMGCEPQCAWSEWLDYSYPMPGPS--GGDFDTYSNIR 2983

Query: 735  AVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSF 772
            A GG+    PL +   A     + L     V    L F
Sbjct: 2984 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDF 3021



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 42/179 (23%), Positives = 69/179 (38%), Gaps = 24/179 (13%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P+PS     T  +P     P +  S ++  S P ++  TS+ + T A  + A   TS  
Sbjct: 4797 TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTH-TSTVLTTKATTTRATSSTSTP 4855

Query: 574  PSA------LMSHTTAFPHVAA-----------------TLSIMDSTFKAPSAVSPIPAV 610
             S       L   TTA    AA                 T     +T  A +  +  P+ 
Sbjct: 4856 SSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSS 4915

Query: 611  IPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP 669
             P  +   ++  T+ +  V   ST +  S       P  ST++++ + +SS  T  SSP
Sbjct: 4916 TPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSP 4974



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSS 176
            C   H      + S  +P+S P T+ +  K     +   S  ST+ P  TP    +LT  
Sbjct: 4194 CNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEP 4253

Query: 177  SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVS 236
            S   TV    GS           +         A   +V   +TT T  S+ +T  S+  
Sbjct: 4254 STTATVTVPTGS-----------TATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG 4302

Query: 237  TPPLIKPVLMSKSVPPS 253
            T   + P L S +  P+
Sbjct: 4303 TATAL-PALRSTATTPT 4318



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 60/278 (21%), Positives = 94/278 (33%), Gaps = 30/278 (10%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P  SP    T PV  S     +   +   PS+   +  T + + T+        + +P 
Sbjct: 4404 TPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPS 4463

Query: 574  PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAV-------------IPSPSHKPSK 620
             S   S TT  P V  T +       +PS+   +                I  PS   S 
Sbjct: 4464 SSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH 4523

Query: 621  TKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVL 680
            T  + +   +  ST +  SP    R  +S  S  +++   +  TS ++  + P K     
Sbjct: 4524 TPAATTGTTQH-STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK----T 4578

Query: 681  NASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLE------PSGRTSLPGGPADIVRQVG 734
              S+ L S   + P  ++       G  P  A  E      P    S  GG  D    + 
Sbjct: 4579 RTSTLLPSSPTSAPITTV----VTTGCEPQCAWSEWLDYSYPMPGPS--GGDFDTYSNIR 4632

Query: 735  AVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSF 772
            A GG+    PL +   A     + L     V    L F
Sbjct: 4633 AAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDF 4670



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 80/407 (19%), Positives = 145/407 (35%), Gaps = 75/407 (18%)

Query: 129  SPSPVSPASNPRTSLVQVKTKACLSGHHSAS-STSKPFKTPK----DNLLTSSSKQHTVF 183
            +P+  S  + P +SL    T+   +   +A+ ST+ P  TP+      +LT+++   T  
Sbjct: 4989 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATA---TTT 5045

Query: 184  PAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSS-SAVSTPPLIK 242
             A GS   P          K+P             +TTTT  +A+ +SS     TPP   
Sbjct: 5046 GATGSVATPSSTPGTAHTTKVP-------------TTTTTGFTATPSSSPGTALTPPTTT 5092

Query: 243  PVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDP 302
            P+    ++  S            +T +  H +    +     R +     P+   G    
Sbjct: 5093 PMSTMSTIHTS------------STPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRI 5140

Query: 303  ETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREIL 362
             T+   T + T  T S +   + PG       +L E                 T    ++
Sbjct: 5141 LTELTTTATTTAATGSTATLSSTPGT----TWILTEPS---------------TIATVMV 5181

Query: 363  PSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPE 422
            P+ S     S LG++ +    PKV +   + P  +    PSS+   ++ T +      P 
Sbjct: 5182 PTGSTATASSTLGTAHT----PKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPT 5237

Query: 423  PPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFD 482
              +  V   + + L                   F + H     FC    +    G  +++
Sbjct: 5238 FSVSTVSSSVLTTLR---------------PTGFPSSHFSTPCFCRAFGQFFSPGEVIYN 5282

Query: 483  RRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPA 529
            +  DR      ++  +H +   ++   P   SP P  +A +++P PA
Sbjct: 5283 KT-DRAGCHFYAVCNQHCDIDRFQGACPT--SPPPVSSAPLSSPSPA 5326



 Score = 33.9 bits (76), Expect = 0.66
 Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 6/159 (3%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P  SP    T PV  S     +   +   PS+   +  T + + T+        + +P 
Sbjct: 3257 TPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPS 3316

Query: 574  PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLS 633
             S   S TT  P V  T +       +PS+   +     S     + + T  ++ + + S
Sbjct: 3317 SSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTS-----ATSGTLGTTHITEPS 3371

Query: 634  TRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSG 672
            T +  +P+      Q ST + SS   SS +T+ S P  G
Sbjct: 3372 TGTSHTPAATTGTTQHSTPALSSPHPSS-RTTESPPSPG 3409



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 33/137 (24%), Positives = 50/137 (36%), Gaps = 13/137 (9%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSS 176
            C   H      + S   P+S P T+ +  +     +   S  ST+ P  TP    +LT  
Sbjct: 3047 CNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEP 3106

Query: 177  SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVS 236
            S   TV    GS           +         A   +V   +TT T  S+ +T  S+  
Sbjct: 3107 STTATVTVPTGS-----------TATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG 3155

Query: 237  TPPLIKPVLMSKSVPPS 253
            T   + P L S +  P+
Sbjct: 3156 TATAL-PALRSTATTPT 3171



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 29/128 (22%), Positives = 49/128 (38%), Gaps = 3/128 (2%)

Query: 127  RPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSSSKQHTVFPA 185
            R + S  +P+S P T+ +  +     +   +   T+ P  TP    +LT  +   T   +
Sbjct: 4847 RATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTAS 4906

Query: 186  KGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVL 245
             GS   P        +   P+        V   ST T + + ++  +  VST      V 
Sbjct: 4907 TGSTATPSSTPGTTWILTEPSTTAT--VTVPTGSTATASSTQATAGTPHVSTTATTPTVT 4964

Query: 246  MSKSVPPS 253
             SK+ P S
Sbjct: 4965 SSKATPSS 4972



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 107/600 (17%), Positives = 197/600 (32%), Gaps = 95/600 (15%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSS 177
            C   H      + S   P+S P T+ +  +     +   S  ST+ P  TP         
Sbjct: 4696 CNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTP--------- 4746

Query: 178  KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVST 237
                     G+   P V                    +   +TT TA S+ +TSSS+  T
Sbjct: 4747 ---------GTAPPPKV--------------------LTSPATTPTATSSKATSSSSPRT 4777

Query: 238  PPLIKPVLMS-------KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSERE 290
               + PVL S        SV P P   L   G LP           + +  P   +S   
Sbjct: 4778 ATTL-PVLTSTATKSTATSVTPIPSSTLGTTGTLP-----------EQTTTPVATMS--T 4823

Query: 291  FDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
              P+         T      + T  T S S   + PG       +L E    +       
Sbjct: 4824 IHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGT----TWILTELTTAATTTAATG 4879

Query: 351  KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS------ 404
                 T+T    P  +    + L  ++ ++      A+P+ +     +L  PS+      
Sbjct: 4880 P----TATPSSTPGTTWILTE-LTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV 4934

Query: 405  -ANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRP 463
               S ++++S+  +  TP          + S  ++       A     L    +T  P  
Sbjct: 4935 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATT--PTA 4992

Query: 464  LAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHI 523
             +F +  S  +G  +          R +  +     +++      P    +     A   
Sbjct: 4993 TSFTAIPSSSLGTTW---------TRLSQTTTPTATMSTATPSSTPETVHTSTVLTATAT 5043

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAF---VTSPDPSALMSH 580
            TT    SV  P S P   +    P ++  T+ +  T +     A     T+P  +    H
Sbjct: 5044 TTGATGSVATPSSTPGTAHTTKVPTTT--TTGFTATPSSSPGTALTPPTTTPMSTMSTIH 5101

Query: 581  TTAFPHVAATLSIMDST---FKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSD 637
            T++ P    T +++ +T    +A ++ +   + + +       T T+ ++     +    
Sbjct: 5102 TSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLS 5161

Query: 638  ESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNS 697
             +P       + ST ++    + S  T+ SS L   H    V   ++   +  +  P +S
Sbjct: 5162 STPGTTWILTEPSTIATVMVPTGSTATA-SSTLGTAHTPKVVTTMATMPTATASTVPSSS 5220



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 30/132 (22%), Positives = 51/132 (38%), Gaps = 12/132 (9%)

Query: 127  RPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSSSKQHTVFPA 185
            R + S  +P+S P T+ +  +     +   +   T+ P  TP    +LT  S   TV   
Sbjct: 3700 RATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVP 3759

Query: 186  KGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVL 245
             GS              K+          +   +TT T +S+ +T SS+  T   + P L
Sbjct: 3760 TGSTATASSTRATAGTLKV----------LTSTATTPTVISSRATPSSSPGTATAL-PAL 3808

Query: 246  MSKSVPPSPEKI 257
             S +  P+   +
Sbjct: 3809 RSTATTPTATSV 3820


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 123/556 (22%), Positives = 217/556 (39%), Gaps = 99/556 (17%)

Query: 363 PSQSGPAQDSLL-GSSGSSGPEPKVASPAKS--RPPNSVLPRPSSANSISSSTSSNHSG- 418
           P  SG  + + L GS+   G   K  +   S   P  + LP   +++ +S  ++++HS  
Sbjct: 99  PISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRP 158

Query: 419 ---HTPEPP----LPPVGGDLASRLSS----DEGEMDGADESEKLDCQFSTHHPRPLAFC 467
              HT   P    +P +  +  +  SS    D     G+  +  L  +++T H RP    
Sbjct: 159 GSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP---G 215

Query: 468 SFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPS--------- 518
           S  + L+                  + ++E  +      + P    SP  S         
Sbjct: 216 STETTLLPDNT------------TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 263

Query: 519 ----PAAHITTPVPASVLQPFSNPSAVY------LPSAPISSRLTSSYIMTSAMLSNAAF 568
               P++  T P P +    F  PS         +P+  IS+R T+S ++  +      +
Sbjct: 264 FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEES----TTY 319

Query: 569 VTSPDPSALM----SHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTS 624
            +SP  +  M    S TT+     +T S   +T    SA S   A++  P+   S   ++
Sbjct: 320 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 379

Query: 625 KSSKVKDLST---RSDESPSNKKRKPQSST--SSSSSSSSSSLQTSLSSPLSGPHKKNCV 679
            ++   D ST   RS+ES ++   +  + T    + S++S  L  S +SP+S    +   
Sbjct: 380 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 439

Query: 680 LNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGS 739
           L  S+        P  +  S    ++  SP +  L P+  TS   G ++      +  GS
Sbjct: 440 LPGST------TTPGLSERSTTFHSSPRSP-ATTLSPASTTS--SGVSEESTTSRSRPGS 490

Query: 740 SDSCPL----SVPSLALHAGDLSLASHNAVSS-----LPLSFDKSEGKKRKNSSSSSKAC 790
           + +       + P L+ H    S  SH++  S     LP S   S   +   +S SS   
Sbjct: 491 THTTAFPDSTTTPGLSRH----STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGS 546

Query: 791 KITKM-PGM---------NSVHKKNPPSLLAPV-PDPVNST----SSRQVGKNSSLALSQ 835
             T + PG          ++    NP S    + PD   S+    +S +V  ++    + 
Sbjct: 547 TDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 606

Query: 836 SSPSSISSPGHSRQNT 851
            SP+S +SPG   ++T
Sbjct: 607 LSPASSTSPGLQGEST 622



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 48/203 (23%), Positives = 78/203 (38%), Gaps = 23/203 (11%)

Query: 519  PAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALM 578
            P++  T P P +    F   S     S   SS  T+ +  +S  L  +   T+   S + 
Sbjct: 1323 PSSKDTMPAPPTTTSAFVELSTTSHGSP--SSTPTTHFSASSTTLGRSEESTTVHSSPVA 1380

Query: 579  SHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDE 638
            + TT  P  + T  +++ +    S+              P  T+T    +    S RS+E
Sbjct: 1381 TATTPSPARSTTSGLVEESTAYHSS--------------PGSTQTMHFPESSTASGRSEE 1426

Query: 639  SPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSL 698
            S     R   SST+ + SS  S+    +  P S       +       +S  +     S 
Sbjct: 1427 S-----RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEEST 1481

Query: 699  SVHNS--NNGVSPLSAKLEPSGR 719
            + H+S   NG++PL A    SGR
Sbjct: 1482 ASHSSPDTNGITPLPAHFTTSGR 1504



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 83/406 (20%), Positives = 152/406 (37%), Gaps = 82/406 (20%)

Query: 518 SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAML---SNAAFVTSPDP 574
           SP +  TT +PAS      +  +    S+  S+    S   T+A+     +  F ++P  
Sbjct: 515 SPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGS 574

Query: 575 SALMSHTTAFPHVAATLSIMDSTFKAPSAV-SPIPAVIPSPSHKPSKTKTSKSSKVKDLS 633
           +    HTT FP    +  I++++ +  S+  SP   + P+ S  P     S + +    S
Sbjct: 575 T----HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 630

Query: 634 TRSDESPSNKKRKP--QSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
           T +  SP +    P  +S+T   S  S+ +     SS  SG  +K+ + ++S   +    
Sbjct: 631 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 690

Query: 692 APPYNSLSVH--NSNNGVSPLSAKLEP-SGRTSLPG-------------------GPADI 729
           +  +++ S    ++ + +SP S ++    G T+ PG                    PA +
Sbjct: 691 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 750

Query: 730 VRQ-VGAVGGSSDSCPLSVPSLALHAG---------------------DLSLASHNAVSS 767
               VG    +S S P S  S    A                      + ++  H+  +S
Sbjct: 751 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 810

Query: 768 L----PLSFDKSEGKKR-----KNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVP---- 814
           +    P +F             ++S++S    + T  PG  +  +   P+ L        
Sbjct: 811 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 870

Query: 815 ---------------DPVNSTSSRQVGKNSSLALSQSSPSSISSPG 845
                           P  ST+S  VG+++   LS SS  + + PG
Sbjct: 871 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 916



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 64/269 (23%), Positives = 105/269 (39%), Gaps = 17/269 (6%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            SP +  TT  P S       P +    S+P S+  T     T+A  S     ++P  S+ 
Sbjct: 1240 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA--SGLLEASTPVHSST 1297

Query: 578  MS-HTTAFPHVAATLSIMDSTFKA-PSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTR 635
             S HTT  P  + T     +TF++ PS+   +PA   + S     + TS  S     +T 
Sbjct: 1298 GSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTH 1357

Query: 636  SDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPY 695
               S +   R  +S+T  SS  ++++  +   S  SG  +++   ++S         P  
Sbjct: 1358 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPES 1417

Query: 696  NSLSVHNSNNGVSPLSA----KLEPSGRTSLPGGPADIVRQVGAVG-----GSSDSCPLS 746
            ++ S  +  +  S  S        PS  ++L   P       G++       SS +   S
Sbjct: 1418 STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS 1477

Query: 747  VPSLALHAGDLSLASHNAVSSLPLSFDKS 775
              S A H    S    N ++ LP  F  S
Sbjct: 1478 EESTASH----SSPDTNGITPLPAHFTTS 1502



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 142/637 (22%), Positives = 219/637 (34%), Gaps = 107/637 (16%)

Query: 129 SPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSK---PFKTPKDNLL--------TSSS 177
           SP   +    P +S    +++   + H S  +T     P ++    LL        +S S
Sbjct: 375 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 434

Query: 178 KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSS----- 232
            + T  P  GS   P +     +    P   ++    +   STT++ VS  ST+S     
Sbjct: 435 METTALP--GSTTTPGLSERSTTFHSSP---RSPATTLSPASTTSSGVSEESTTSRSRPG 489

Query: 233 --------SAVSTPPLIKPVLMSKSVPPSPEKILNGKGILP---TTIDKKHQNGTKNSNK 281
                    + +TP L +    S S P S +  L     LP   TT     ++ T +S+ 
Sbjct: 490 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL-----LPASTTTSGPSQESTTSHSSS 544

Query: 282 PYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKA 341
                           G  D       T +L+    S +   + PG       L  +   
Sbjct: 545 ----------------GSTDTALSPGSTTALSFGQESTTFH-SNPG--STHTTLFPDSTT 585

Query: 342 KSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPR 401
            S   E   + H  T +     S +      L G S +    P       S P  +  P 
Sbjct: 586 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP- 644

Query: 402 PSSANSISSSTSSNHS-GHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHH 460
                 +  ST+ + S G TP    P      AS  +S          SEK     S+  
Sbjct: 645 ------VEESTTYHRSPGSTPTTHFP------ASSTTSGH--------SEKSTIFHSSPD 684

Query: 461 PRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPA 520
                  S  S   GRG     R         ++ +     S     +  A+ +   SP 
Sbjct: 685 ASGTTPSSAHSTTSGRGESTTSRISPG-----STEITTLPGSTTTPGLSEASTTFYSSPR 739

Query: 521 AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSH 580
           +  TT  PAS+        +    S P S+  T S   T+    +    T    S   + 
Sbjct: 740 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTE 799

Query: 581 TTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESP 640
           TT FPH + T S+     + P+     PA     +H    T+ S +S + + ST    SP
Sbjct: 800 TTVFPH-STTTSVHG---EEPTTFHSRPA----STHTTLFTEDSTTSGLTEESTAFPGSP 851

Query: 641 -SNKKRKPQSST-------SSSSSSSSSSLQTSLS------SPLSGPHKKNCVLNASSAL 686
            S +   P + T       S++  SSS S  T LS      S L G    + +  +S+  
Sbjct: 852 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 911

Query: 687 NSYQAAPPYNSLSVHNSNNGVSPLS--AKLEPSGRTS 721
            +   +P   SLS  ++    SP S  A L P+  TS
Sbjct: 912 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 948


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 71/354 (20%), Positives = 138/354 (38%), Gaps = 30/354 (8%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ +   ++  T++   ++A  S+    T+P P  L S  T 
Sbjct: 4233 STPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG-TAPPPKVLTSPATT 4291

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A TL ++ ST    +A S    V P PS     T T        
Sbjct: 4292 PTATSSKATSSSSPRTATTLPVLTSTATKSTATS----VTPIPSSTLGTTGTLPEQTTTP 4347

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            ++T S   PS+      +ST  ++ ++++   +S S+P S P     +   ++A  +  A
Sbjct: 4348 VATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAA 4407

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGG----PADIVRQVGAVGGSSDSCPLSV 747
              P    +  +S  G + +  +L  +  T+   G    P+        +   S +  ++V
Sbjct: 4408 TGP---TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV 4464

Query: 748  P--SLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKN 805
            P  S A  +   + A    VS+   +   +  K   +SS  +     T +P + S     
Sbjct: 4465 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGT----ATALPALRSTATTP 4520

Query: 806  PPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRQNTNRTGRIRT 859
              +    +P     T+  ++ + ++   + S+ +  S+P     +T  T    T
Sbjct: 4521 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATT 4574



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/182 (22%), Positives = 76/182 (41%), Gaps = 17/182 (9%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ + P ++  T++   ++A    +   T+P P  L +  T 
Sbjct: 1890 STPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTAT-PTSTLRTAPPPKVLTTTATT 1948

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A  L  + ST   P+A S    V P PS     T T  S     
Sbjct: 1949 PTVTSSKATPSSSPGTATALPALRSTATTPTATS----VTPIPSSSLGTTWTRLSQTTTP 2004

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
             +T S  +PS+      +ST  +++++++    S+++P S P   +     ++    + A
Sbjct: 2005 TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2064

Query: 692  AP 693
             P
Sbjct: 2065 TP 2066



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 68/357 (19%), Positives = 134/357 (37%), Gaps = 55/357 (15%)

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTT- 582
            +TP  +S   P S P   ++ +   ++  T++   ++A+ S+    T+P P  L S  T 
Sbjct: 2976 STPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG-TAPPPKVLTSTATT 3034

Query: 583  -----------AFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKD 631
                       + P  A TL ++ ST    +A S      P PS     T T        
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATS----FTPIPSFTLGTTGTLPEQTTTP 3090

Query: 632  LSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
            ++T S   PS+      +ST  ++ ++++   +S+S+P S P     +   ++A  +  A
Sbjct: 3091 MATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA 3150

Query: 692  APPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLA 751
              P    +  +S  G + +  +   +   ++P G                    +  S  
Sbjct: 3151 TGP---TATPSSTPGTTWILTEPSTTATVTVPTGST-----------------ATASSTR 3190

Query: 752  LHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLA 811
              AG L + +  A +   +S           ++ SS     T +P + S       + + 
Sbjct: 3191 ATAGTLKVLTSTATTPTVIS---------SRATPSSSPGTATALPALRSTATTPTATSVT 3241

Query: 812  PVPDPVNSTSSRQVGKNS--SLALSQSSPSSISSPGH-------SRQNTNRTGRIRT 859
             +P     T+  ++ + +  +  +S ++PSS     H       +   T  TG + T
Sbjct: 3242 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVAT 3298



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 78/389 (20%), Positives = 132/389 (33%), Gaps = 49/389 (12%)

Query: 510  PAADSPLPSPAAHITTPVPASVL-------QPFSNPSAVYLPSAPISS---RLTSSYIMT 559
            PA  S   +P A   T +P+S L          + P+A    + P S+     TS+ + T
Sbjct: 3783 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTT 3842

Query: 560  SAMLSNAA-FVTSPDPSALMSHTTAFPHVAAT-----------------LSIMDSTFKAP 601
            +A  + A   V +P  +   +HTT  P    T                 + I  +T    
Sbjct: 3843 TATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTT 3902

Query: 602  SAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQ------------S 649
            S  +  P+ +P  +H P+   T+ ++           S       P             S
Sbjct: 3903 SGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGS 3962

Query: 650  STSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSP 709
            +T+ SS+  ++ +   L++  + P   +  +  SSAL +    PP  + +       +SP
Sbjct: 3963 TTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTH-TPPVPNTTATTHGRSLSP 4021

Query: 710  LSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLP 769
             S     +  TS   G            G+S + P +      H+     + H   SS  
Sbjct: 4022 SSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT-PAATTGTTQHSTPALSSPH--PSSRT 4078

Query: 770  LSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNS 829
                 S G      ++++     T  P      K    +LL   P     T+    G   
Sbjct: 4079 TESPPSPGTTTPGHTTATSRTTATATPS-----KTRTSTLLPSSPTSAPITTVVTTGCEP 4133

Query: 830  SLALSQSSPSSISSPGHSRQNTNRTGRIR 858
              A S+    S   PG S  + +    IR
Sbjct: 4134 QCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4162



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 75/385 (19%), Positives = 139/385 (36%), Gaps = 41/385 (10%)

Query: 510  PAADSPLPSPAAHITTPVPASVL-------QPFSNPSAVYLPSAPISSRLTS--SYIMTS 560
            PA  S   +P A   TP+P+S L          + P+A    + P S+  T+  S ++T+
Sbjct: 1969 PALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTA 2028

Query: 561  AMLSNAAF--VTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSP------------ 606
               +  A   V +P  +   +HTT  P    T      +    +A++P            
Sbjct: 2029 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTT 2088

Query: 607  -----IPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSS 661
                  P+ IP  +H  +   T+ ++           S       P  +T++++ +++ S
Sbjct: 2089 RGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 2148

Query: 662  LQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTS 721
                 S+P + P        A++   +     P ++L   ++     P+   +  +   S
Sbjct: 2149 TTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHT----PPVPNTMATTHGRS 2204

Query: 722  LPGGPADIVRQV------GAVGGSSDSCPLSVPSLALHAGDLSLASHN--AVSSLPLSFD 773
            LP      VR        G +G +  + P +V S  L A       H+  A+SS   S  
Sbjct: 2205 LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL-AATTGTTQHSTPALSSPHPSSR 2263

Query: 774  KSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLAL 833
             +E      +++       ++     +  K    +LL   P     T+   +G     A 
Sbjct: 2264 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAW 2323

Query: 834  SQSSPSSISSPGHSRQNTNRTGRIR 858
            S+    S   PG S  + +    IR
Sbjct: 2324 SEWLDYSYPMPGPSGGDFDTYSNIR 2348



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/182 (25%), Positives = 72/182 (39%), Gaps = 28/182 (15%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P+PS     T  VPA    P S  S ++  S P ++  TS+ + T+A ++ A   T+  
Sbjct: 4754 TPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTH-TSTVLTTTATMTRATNSTATP 4812

Query: 574  PSAL-----------MSHTTAFPHVAATLSIMDST---FKAPSAVSPIPAVIPSPS---- 615
             S L            + TTA     ATLS    T      PS ++ +  ++P+ S    
Sbjct: 4813 SSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATV--MVPTGSTATA 4870

Query: 616  -------HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
                   H P    T  +      ST    S     R P    SS  + S S++ +S+ +
Sbjct: 4871 SSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLT 4930

Query: 669  PL 670
             L
Sbjct: 4931 TL 4932



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 125/641 (19%), Positives = 215/641 (33%), Gaps = 90/641 (14%)

Query: 145  QVKTKACLSGH----HSASSTSKPFKTPKDN-LLTSSSKQHTVFPAKGSRDKPCVPVPVV 199
            +++   C  GH     + SST+ P  TP    +LT  +   T     GS     +P    
Sbjct: 2963 EIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGST---AIPSSTP 3019

Query: 200  SLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK-------SVPP 252
                 P ++ +        +TT TA S+ +TSSS+  T   + PVL S        S  P
Sbjct: 3020 GTAPPPKVLTS-------TATTPTATSSKATSSSSPRTATTL-PVLTSTATKSTATSFTP 3071

Query: 253  SPEKILNGKGILP-------TTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETK 305
             P   L   G LP        T+   H + T  +      L+ +         +  P + 
Sbjct: 3072 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSST 3131

Query: 306  KPCTRSLT-----CKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTRE 360
               T  LT       T + +   A P        +L E    +            +STR 
Sbjct: 3132 PGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRA 3191

Query: 361  ILPS----QSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNH 416
               +     S     +++ S  +    P  A+   +    +  P  +S  +I SS+    
Sbjct: 3192 TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3251

Query: 417  SGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGR 476
                 +   P      A+  S+ E                + H    L   +  +R  G 
Sbjct: 3252 WTRLSQTTTPTATMSTATPSSTPE----------------TVHTSTVLTTTTTTTRATGS 3295

Query: 477  GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADS-----PLPSPAAHITTPVPASV 531
                          A  S      ++    K+P    +     P  SP   +T PV  S 
Sbjct: 3296 -------------VATPSSTPGTAHTT---KVPTTTTTGFTATPSSSPGTALTPPVWIST 3339

Query: 532  LQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHT-TAFPHVAAT 590
                +   +   PS+   +  T++ + T+        + +P  S   S T  +    A T
Sbjct: 3340 TTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 3399

Query: 591  LSIMDSTFKAPS--AVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQ 648
            ++   ST    S    +PIP V+ + +  P+ T ++ +      +T +   P+       
Sbjct: 3400 ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 3459

Query: 649  SSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVS 708
             S   SS  +  +  TS +S + G       +   S + S+  A    S + H+     +
Sbjct: 3460 RSLPPSSPHTVRTAWTSATSGILG----TTHITEPSTVTSHTPAAT-TSTTQHS-----T 3509

Query: 709  PLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPS 749
            P  +   PS RT+    P+      G   G+S +   + PS
Sbjct: 3510 PALSSPHPSSRTT-ESPPSPGTTTPGHTRGTSRTTATATPS 3549



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 75/362 (20%), Positives = 141/362 (38%), Gaps = 34/362 (9%)

Query: 518  SPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSAL 577
            S A   +TP    +L   S  + V +P+   S+   SS   T+     +   T+P  ++ 
Sbjct: 4439 STATPSSTPGTTWILTEPSTTATVTVPTG--STATASSTQATAGTPHVSTTATTPTVTSS 4496

Query: 578  MSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSD 637
             +  ++ P  A  L  + ST   P+A S     IPS S   + T+ S+++     +T S 
Sbjct: 4497 KATPSSSPGTATALPALRSTATTPTATSF--TAIPSSSLGTTWTRLSQTTT--PTATMST 4552

Query: 638  ESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNS 697
             +PS+      +ST  +++++++    S+++P S P   +     ++    + A P  + 
Sbjct: 4553 ATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP 4612

Query: 698  LSVHNSNNGVS----PLSAKLEPSGRTSLPG---GPADIVRQV---------GAVGGSSD 741
             +       +S    P +     SG T  P    G     R +         G++   S 
Sbjct: 4613 GTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSS 4672

Query: 742  SCPLS--VPSLALHAGDLSLA-SHNAVSSLP---------LSFDKSEGKKRKNSSSSSKA 789
            S   S   PSL   A  ++   S    SS P          S   +       ++SSS  
Sbjct: 4673 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSP 4732

Query: 790  CKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRQ 849
               T +P + S   K+  +   P+P     T+     + ++   + S+  + S+P  +  
Sbjct: 4733 RTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHT 4792

Query: 850  NT 851
            +T
Sbjct: 4793 ST 4794



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 49/167 (29%), Positives = 72/167 (43%), Gaps = 18/167 (10%)

Query: 508  IPPAADSPLPSPAAHITTPVPASVL-----QPFSNPSA-VYLPSAPISSRLTSSYIMTSA 561
            IPP   +   +PAA  +T  P+S L      P  N +A  +  S P SS  T     TSA
Sbjct: 3418 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSA 3477

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKT 621
                       +PS + SHT A    A T +   ST   P+  SP P+   + S  PS  
Sbjct: 3478 TSGILGTTHITEPSTVTSHTPA----ATTSTTQHST---PALSSPHPSSRTTES-PPSPG 3529

Query: 622  KTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
             T+         T +  +PS    K ++ST   SS +S+ + T +++
Sbjct: 3530 TTTPGHTRGTSRTTATATPS----KTRTSTLLPSSPTSAPITTVVTT 3572



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 110/582 (18%), Positives = 189/582 (32%), Gaps = 105/582 (18%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSS 177
            C   H      + S   P+S P T+ +  +     +   S  ST+ P  TP         
Sbjct: 4226 CNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTP--------- 4276

Query: 178  KQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVST 237
                     G+   P V                    +   +TT TA S+ +TSSS+  T
Sbjct: 4277 ---------GTAPPPKV--------------------LTSPATTPTATSSKATSSSSPRT 4307

Query: 238  PPLIKPVLMS-------KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSERE 290
               + PVL S        SV P P   L   G LP           + +  P   +S   
Sbjct: 4308 ATTL-PVLTSTATKSTATSVTPIPSSTLGTTGTLP-----------EQTTTPVATMS--T 4353

Query: 291  FDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
              P+         T      + T  T S S   + PG       +L E    +       
Sbjct: 4354 IHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGT----TWILTELTTAATTTAATG 4409

Query: 351  KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS------ 404
                 T+T    P  +    + L  ++ ++      A+P+ +     +L  PS+      
Sbjct: 4410 P----TATPSSTPGTTWILTE-LTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTV 4464

Query: 405  -ANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRP 463
               S ++++S+  +  TP          + S  ++       A     L    +T  P  
Sbjct: 4465 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATT--PTA 4522

Query: 464  LAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHI 523
             +F +  S  +G  +          R +  +     +++      P    +     A   
Sbjct: 4523 TSFTAIPSSSLGTTW---------TRLSQTTTPTATMSTATPSSTPETVHTSTVLTATAT 4573

Query: 524  TTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTA 583
            TT    SV  P S P   +    P ++  T+ +  T +     A       S   + TT 
Sbjct: 4574 TTGATGSVATPSSTPGTAHTTKVPTTT--TTGFTATPSSSPGTALTPPVWISTTTTPTTT 4631

Query: 584  FP----------------HVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSS 627
             P                H A  L+   +T    S  +P  +   S +  PS T T+ + 
Sbjct: 4632 TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGT-PPSLTTTATTI 4690

Query: 628  KVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP 669
                 +T    +P      P  ++++++ +++SS  TS SSP
Sbjct: 4691 TATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSP 4732



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 18/163 (11%)

Query: 508  IPPAADSPLPSPAAHITTPVPASVLQPFSNP------SAVYLPSAPISSRLTSSYIMTSA 561
            IPP   +   +PAA   T  P+S L     P      +  +  S P SS  T     TSA
Sbjct: 2161 IPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSA 2220

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKT 621
                       +PS + SHT A    A T +   ST   P+  SP P+   + S  PS  
Sbjct: 2221 TSGILGTTHITEPSTVTSHTLA----ATTGTTQHST---PALSSPHPSSRTTES-PPSPG 2272

Query: 622  KTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
             T+         T +  +PS    K ++ST   SS +S+ + T
Sbjct: 2273 TTTPGHTTATSRTTATATPS----KTRTSTLLPSSPTSAPITT 2311



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 18/167 (10%)

Query: 508  IPPAADSPLPSPAAHITTPVPASVL-----QPFSNPSA-VYLPSAPISSRLTSSYIMTSA 561
            IPP   +   +PAA  +T  P+S L      P  N +A  +  S   SS  T     TSA
Sbjct: 3975 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA 4034

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKT 621
                       +PS   SHT A    A T +   ST   P+  SP P+   + S  PS  
Sbjct: 4035 TSGTLGTTHITEPSTGTSHTPA----ATTGTTQHST---PALSSPHPSSRTTES-PPSPG 4086

Query: 622  KTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
             T+         T +  +PS    K ++ST   SS +S+ + T +++
Sbjct: 4087 TTTPGHTTATSRTTATATPS----KTRTSTLLPSSPTSAPITTVVTT 4129



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 93/469 (19%), Positives = 163/469 (34%), Gaps = 44/469 (9%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSS 176
            C   H      + S  +P+S P T+ +  K     +   S  ST+ P  TP    +LT  
Sbjct: 3669 CNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEP 3728

Query: 177  SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVS 236
            S   TV    GS           +         A   +V   +TT T  S+ +T  S+  
Sbjct: 3729 STTATVTVPTGS-----------TATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG 3777

Query: 237  TPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKH 296
            T   +  +  + + P +          L TT  +  Q  T  +       S      +  
Sbjct: 3778 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTS 3837

Query: 297  CGVLDPETKKPCTRSLT--CKTHSLSHRRAVPGRKKQ-FDLLLAEHKAKSREKEV--KDK 351
              +    T    T S+     T   +H   VP      F +  +     +R   V     
Sbjct: 3838 TVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTT 3897

Query: 352  EHLLTSTREILPSQ--SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPR-PSSANSI 408
                TS   + PS         ++L ++ ++     +A+P+ S   +   P   ++A +I
Sbjct: 3898 TTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTI 3957

Query: 409  SSSTSSNHSGHTP-EPPLPPVGGDLASRLSSDEGEMD-----GADESEKLDCQFSTHHPR 462
            +++ S+ +   TP   P+PPV    A+  ++    +      G   +  +    +T H R
Sbjct: 3958 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGR 4017

Query: 463  PL----------AFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPA- 511
             L          A+ S  S  +G  +            A  +   +H    +    P + 
Sbjct: 4018 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 4077

Query: 512  -ADSPLPSPA----AHIT-TPVPASVLQPFSNPSAVYLPSAPISSRLTS 554
              +SP PSP      H T T    +   P    ++  LPS+P S+ +T+
Sbjct: 4078 TTESP-PSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITT 4125



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 47/216 (21%), Positives = 82/216 (37%), Gaps = 8/216 (3%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
            +P  SP    T PV  S     +   +   PS+   +  T + + T+        + +P 
Sbjct: 2622 TPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPS 2681

Query: 574  PSALMSHT-TAFPHVAATLSIMDSTFKAPS--AVSPIPAVIPSPSHKPSKTKTSKSSKVK 630
             S   S T  +    A T++   ST    S    +PIP V+ + +  P+ T    S+   
Sbjct: 2682 SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT---SSTVTP 2738

Query: 631  DLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQ 690
              +  +  +P        +   S S SS  +++T+ +S  SG      +   S+  +   
Sbjct: 2739 SSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTP 2798

Query: 691  AAPPYNSLSVHNSNNGVSPLSAKLE--PSGRTSLPG 724
            AA    +     + +   P S   E  PS  T+ PG
Sbjct: 2799 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2834



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 48/163 (29%), Positives = 67/163 (41%), Gaps = 18/163 (11%)

Query: 508  IPPAADSPLPSPAAHITTPVPASVL-----QPFSNPSA-VYLPSAPISSRLTSSYIMTSA 561
            IPP   +   +PAA  +T  P+S L      P  N +A  +  S   SS  T     TSA
Sbjct: 2718 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA 2777

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKT 621
                       +PS   SHT A    A T +   ST   P+  SP P+   + S  PS  
Sbjct: 2778 TSGTLGTTHITEPSTGTSHTPA----ATTGTTQHST---PALSSPHPSSRTTES-PPSPG 2829

Query: 622  KTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
             T+         T +  +PS    K ++ST   SS +S+ + T
Sbjct: 2830 TTTPGHTRATSRTTATATPS----KTRTSTLLPSSPTSAPITT 2868



 Score = 33.5 bits (75), Expect = 0.87
 Identities = 96/487 (19%), Positives = 167/487 (34%), Gaps = 72/487 (14%)

Query: 118  CERRHGSMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSS 176
            C   H      + S   P+S P T+ +  +     +   S  ST+ P  TP    +LT  
Sbjct: 2412 CNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEP 2471

Query: 177  SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVS 236
            S   TV    GS           +         A   +V   +TT T  S+ +T  S+  
Sbjct: 2472 STTATVTVPTGS-----------TATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG 2520

Query: 237  TPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKH 296
            T   +  +  + + P +          L TT  +  Q  T     P   +S     P+  
Sbjct: 2521 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTT-----PTATMSTA--TPSST 2573

Query: 297  CGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLL----------AEHKAKSREK 346
               +   T    T + T  T S++   + PG      +L           +     +R  
Sbjct: 2574 PETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTL 2633

Query: 347  EVKDKEHLLTSTR--EILPSQ--SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPR- 401
             V        +TR   + PS         ++L ++ ++     +A+P+ S   +   P  
Sbjct: 2634 PVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSL 2693

Query: 402  PSSANSISSSTSSNHSGHTP-EPPLPPVGGDLASRLSSDEGEMD-----GADESEKLDCQ 455
             ++A +I+++ S+ +   TP   P+PPV    A+  ++    +      G   +  +   
Sbjct: 2694 TTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT 2753

Query: 456  FSTHHPRPL----------AFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMW 505
             +T H R L          A+ S  S  +G  +            A  +   +H      
Sbjct: 2754 TATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHST---- 2809

Query: 506  KKIPPAADSPLPS-------PAAHITTP-------VPASVLQPFSNPSAVYLPSAPISSR 551
                PA  SP PS       P+   TTP          +   P    ++  LPS+P S+ 
Sbjct: 2810 ----PALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAP 2865

Query: 552  LTSSYIM 558
            +T+   M
Sbjct: 2866 ITTVVTM 2872



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 38/179 (21%), Positives = 66/179 (36%), Gaps = 16/179 (8%)

Query: 509  PPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAF 568
            P +      +P    TT    +     +  S+      P S   T++ I  +   +N + 
Sbjct: 2652 PSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS 2711

Query: 569  VTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIP---------AVIPSPSHKPS 619
                 P   +  TTA    A + ++  S+    +   P+P         ++ PS  H   
Sbjct: 2712 TPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVR 2771

Query: 620  KTKTSKSS------KVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSG 672
               TS +S       + + ST +  +P+      Q ST + SS   SS +T+ S P  G
Sbjct: 2772 TAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSS-RTTESPPSPG 2829



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 44/241 (18%), Positives = 80/241 (33%), Gaps = 14/241 (5%)

Query: 509  PPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAF 568
            P +      +P    TT    +     +  S+      P S   T++ I  +   +N + 
Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSS 3968

Query: 569  VTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSK 628
                 P   +  TTA    A + ++  S+    +   P+P    +   +     +  + +
Sbjct: 3969 TPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVR 4028

Query: 629  VKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNS 688
                S  S    +    +P + TS + ++++ + Q S +  LS PH  +           
Sbjct: 4029 TAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS-TPALSSPHPSSRTTE------- 4080

Query: 689  YQAAPPYNSLSVHNSNNGVSPLSAKLEPS-GRTS--LPGGPADIVRQVGAVGGSSDSCPL 745
               +PP    +        S  +A   PS  RTS  LP  P           G    C  
Sbjct: 4081 ---SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAW 4137

Query: 746  S 746
            S
Sbjct: 4138 S 4138



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 30/132 (22%), Positives = 51/132 (38%), Gaps = 12/132 (9%)

Query: 127  RPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDN-LLTSSSKQHTVFPA 185
            R + S  +P+S P T+ +  +     +   +   T+ P  TP    +LT  S   TV   
Sbjct: 3120 RATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVP 3179

Query: 186  KGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVL 245
             GS              K+          +   +TT T +S+ +T SS+  T   + P L
Sbjct: 3180 TGSTATASSTRATAGTLKV----------LTSTATTPTVISSRATPSSSPGTATAL-PAL 3228

Query: 246  MSKSVPPSPEKI 257
             S +  P+   +
Sbjct: 3229 RSTATTPTATSV 3240


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 92/369 (24%), Positives = 137/369 (37%), Gaps = 37/369 (10%)

Query: 517 PSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRL--TSSYIMTSAMLSNAAFVTSPDP 574
           PS A+  TTP  AS+    S  +A+ +PS    +R    +S  MT +  S         P
Sbjct: 125 PSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASP 184

Query: 575 SALMSHT--TAFPHVAATLSIMDSTFKAPSAVS-PIPAVIP---SPSHKPSKTKTS-KSS 627
           + + S T  T  P   A+L+ MDST      +S   P   P   SP+  P +   S   S
Sbjct: 185 TGMPSRTSPTGMPS-TASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPS 243

Query: 628 KVKDLSTRSDESPSNK-KRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSA- 685
               + T    SP+    R   +   S++S + +  + S +SP   P + +  +  S+A 
Sbjct: 244 TALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTAS 303

Query: 686 -LNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCP 744
            +     A P   LS  +     S  S    P  R S+   P+    +    G  S + P
Sbjct: 304 LMRMLPRASPTGMLSRTSLTKMDSTASISRTPP-RASITRTPS----RASPTGKPSTASP 358

Query: 745 LSVPSLALHAGDLSLASHNAVSS---------------LPLSFDKSEGKKRKNSSSSSKA 789
              PS A   G  S AS   +SS                P +   +    R + +     
Sbjct: 359 TGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSR 418

Query: 790 CKITKMPGMNSVHKKNP---PSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGH 846
             ITKM    S  +  P   P+   P   P  + S        S A    SPS+ +SP  
Sbjct: 419 TSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPST-ASPTG 477

Query: 847 SRQNTNRTG 855
           S    + TG
Sbjct: 478 SPSTASPTG 486



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 91/416 (21%), Positives = 151/416 (36%), Gaps = 83/416 (19%)

Query: 507 KIPPAADSPL-PSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMT------ 559
           + PP A   + PS A+   TP  AS     S  S   +PS    +++ S+  +T      
Sbjct: 159 RTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRA 218

Query: 560 --------------------SAMLSNAAFVTSP---DPSALMSHTTAFPHVAATLSIMDS 596
                               S M S A  + +P    P+ ++S T        +L+ MDS
Sbjct: 219 SPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRT--------SLTKMDS 270

Query: 597 TFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLS-----------------TRSDES 639
           T  A    +P      SP+  PS+   S +     L                  T+ D +
Sbjct: 271 T--ASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDST 328

Query: 640 PSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHK-------KNCVLNASSALNSYQAA 692
            S  +  P++S + + S +S + + S +SP   P +           L   S+  S    
Sbjct: 329 ASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGT 388

Query: 693 PPYNSLSVHNSNNGVSPLSAKLEPSG---RTSL-----PGGPADIVRQVGAVGGSSDSCP 744
           PP  S +   S   ++    +  P+G   RTS+        P     +    G    + P
Sbjct: 389 PPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASP 448

Query: 745 LSVPSLALHAGDLSLASHNAVSSL------PLSFDKSEGKKRKNSSSSSKACKITKMPGM 798
              PS A   G  S AS     S       P +   +    R + + +     +TKM   
Sbjct: 449 TGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMEST 508

Query: 799 NSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRQNTNRT 854
            S+ +   PS  +P   P  ST+S     +++LA+   S ++++    SR +  RT
Sbjct: 509 ASITR--TPSRASPTWTP--STASPTGSPSTALAMGSPSRAALTRT-PSRASLTRT 559



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 76/337 (22%), Positives = 127/337 (37%), Gaps = 43/337 (12%)

Query: 525 TPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAM-LSNAAFVTSPDPSALMSHTTA 583
           TP  AS   P   PS   L   P  + LT +    S M   + A +T   P A +  TT+
Sbjct: 7   TPSRAS---PTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTS 63

Query: 584 FPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNK 643
                           A   VSP  A +         T+T   + +K +  R+    S  
Sbjct: 64  M---------------ASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRA----SRT 104

Query: 644 KRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSAL-------NSYQAAPPYN 696
           +  P++S     S++S +   S +S  + P + +  +  S+A         S    PP  
Sbjct: 105 RTLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRA 164

Query: 697 SLSVHNSNNGVSPLSAKLEPSG---RTSLPGGP--ADIVRQVGAVGGS---SDSCPLSVP 748
           SL++  S   ++    +  P+G   RTS  G P  A + +       +   S + P   P
Sbjct: 165 SLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTP 224

Query: 749 SLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHK-KNPP 807
             A   G    AS   +S +P +        R + +       +TKM    S+ +  + P
Sbjct: 225 PRASPTGSPPRAS---LSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRP 281

Query: 808 SLLAPVPDPVNSTSSRQVGKNSSL-ALSQSSPSSISS 843
           S  +P   P  ++ S      S +  L ++SP+ + S
Sbjct: 282 STASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLS 318


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 92/348 (26%), Positives = 137/348 (39%), Gaps = 30/348 (8%)

Query: 514 SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPD 573
           SPL S      + VP+ +    S PS V  P + + S L+    + S + S  + V SP 
Sbjct: 108 SPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSP- 166

Query: 574 PSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSP-------SHKPSKTKTSKS 626
           PS + S  +  P      S++      PS V   P+ +PSP       S  PS    S  
Sbjct: 167 PSDVPSPPSDVP------SLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPS--PPSDV 218

Query: 627 SKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSAL 686
             + D+ +   + PS     P  S   S  S   SL + + SP S     + V +  S +
Sbjct: 219 PLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVPSLLSDV 278

Query: 687 NSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSD--SCP 744
            S  +  P     V +  + V  L + + PS  + +P  P+DI    G     SD  S P
Sbjct: 279 PSLPSDVPSLLSGVPSPPSDVPSLLSDV-PSPPSDVPSPPSDIPLLSGVPSPPSDVPSPP 337

Query: 745 LSVPSLALHAGDLSLAS--HNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVH 802
             VPS      D+ L S   + +S +PL            S   S    +     + S H
Sbjct: 338 SDVPS---PPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPH 394

Query: 803 KKNPPSLLAPVPDPVNSTSSRQVGKNS------SLALSQSSPSSISSP 844
           + + PSLL+ VP  ++   S   G  S       L+   S PS + SP
Sbjct: 395 RLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPSP 442



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 73/266 (27%), Positives = 104/266 (39%), Gaps = 25/266 (9%)

Query: 510 PAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFV 569
           P+  S +PS  + + +P P+ V  P   PS V  P + + S L+      S + S  + V
Sbjct: 143 PSLLSDVPSLLSGVPSP-PSDVPSP---PSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDV 198

Query: 570 TSPDPSA-LMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSK 628
            SP     L+S   + P     LS + S    PS V  +P+ +PS S  PS      S  
Sbjct: 199 PSPPSDVPLLSDVPSPPSDVPLLSDVPSP---PSDVPSLPSDVPSLSGVPSPPSDVPSLL 255

Query: 629 VKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNS 688
               S  SD SP +      S   S  S   S L    S P   P   + V +  S + S
Sbjct: 256 SGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPS 315

Query: 689 YQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSD------- 741
             +  P  S        GV P      PS  + +P  P+D+    G     SD       
Sbjct: 316 PPSDIPLLS--------GV-PSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGV 366

Query: 742 -SCPLSVPSLALHAGDLSLASHNAVS 766
            S P  VPSL +    L ++ ++ VS
Sbjct: 367 PSPPSDVPSLLMSPHRLLMSHYSLVS 392


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 51/194 (26%), Positives = 76/194 (39%), Gaps = 23/194 (11%)

Query: 608 PAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLS 667
           PA   S S  PS T  + + K    S R  +   N+    +   S     SSS L TS S
Sbjct: 817 PATKDSESAPPSHTSDTPAEKALPKSKRKRKC-DNEDDYREIKKSQGEKDSSSRLATSTS 875

Query: 668 SPLSGPHKKNCVLNASSAL-----NSYQAAPPYNSLSVHNSNNGVSP-LSAKLEPSGRTS 721
           + LS  H   C +N +S       N      P + LS  + +   S  L++   P+G + 
Sbjct: 876 NTLSANH---CNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSL 932

Query: 722 LPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRK 781
                            SS   P +   L  H GDL+ A+HN   ++PL   + + K   
Sbjct: 933 F-------------TSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWS 979

Query: 782 NSSSSSKACKITKM 795
             S+  + CK  K+
Sbjct: 980 PGSNGHRDCKRQKL 993



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 22/69 (31%), Positives = 28/69 (40%)

Query: 609 AVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
           AV+  P+ + S   +  SS      + S  S S       S T SSSS S  S     SS
Sbjct: 421 AVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSS 480

Query: 669 PLSGPHKKN 677
           P + P   N
Sbjct: 481 PEAEPASSN 489


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 51/194 (26%), Positives = 76/194 (39%), Gaps = 23/194 (11%)

Query: 608 PAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLS 667
           PA   S S  PS T  + + K    S R  +   N+    +   S     SSS L TS S
Sbjct: 792 PATKDSESAPPSHTSDTPAEKALPKSKRKRKC-DNEDDYREIKKSQGEKDSSSRLATSTS 850

Query: 668 SPLSGPHKKNCVLNASSAL-----NSYQAAPPYNSLSVHNSNNGVSP-LSAKLEPSGRTS 721
           + LS  H   C +N +S       N      P + LS  + +   S  L++   P+G + 
Sbjct: 851 NTLSANH---CNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSL 907

Query: 722 LPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRK 781
                            SS   P +   L  H GDL+ A+HN   ++PL   + + K   
Sbjct: 908 F-------------TSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWS 954

Query: 782 NSSSSSKACKITKM 795
             S+  + CK  K+
Sbjct: 955 PGSNGHRDCKRQKL 968



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 22/69 (31%), Positives = 28/69 (40%)

Query: 609 AVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSS 668
           AV+  P+ + S   +  SS      + S  S S       S T SSSS S  S     SS
Sbjct: 396 AVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSS 455

Query: 669 PLSGPHKKN 677
           P + P   N
Sbjct: 456 PEAEPASSN 464


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 84/361 (23%), Positives = 131/361 (36%), Gaps = 40/361 (11%)

Query: 507  KIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMT----SAM 562
            K  PA  +P+ +P   +   +P+S  +  + PS+   P AP ++ L+     T     A+
Sbjct: 1491 KKAPATPAPMGAPT--LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548

Query: 563  LSNAAFVTSPDPSALMSHTTAFP------HVAATLSIMDSTFKA----------PSAVSP 606
            +  A  V SP  +  +      P        ++  ++  ST+K           P+  SP
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 607  IPAVIPSPSH--KPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQT 664
             P   P+P     PS  K   +   K   T    +PS+ K  P S  S +    ++  Q 
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668

Query: 665  SLSSPLS-GPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLP 723
            S   P   GP     VL A +  ++     P         ++  SP     +PS +    
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP-DPSAKNGSK 1727

Query: 724  GGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNS 783
            G P   V     +    DS   +    A H+    LA   + +S PL+    E    K  
Sbjct: 1728 G-PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786

Query: 784  SSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISS 843
            S+S  A               +PP  L   P PV +   +Q    SS  L   SPS   +
Sbjct: 1787 SASVSAAP-------------SPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833

Query: 844  P 844
            P
Sbjct: 1834 P 1834



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 93/398 (23%), Positives = 151/398 (37%), Gaps = 65/398 (16%)

Query: 510  PAADSPLPSPAAHITTP--VPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAA 567
            P     +PSP    T+P  +P S  +  + P      + P    LT   + T   L  A 
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV-TPVSLKKAP 1447

Query: 568  FVTSP-----------DPS--ALMSHTTAFPHVAATLSIMDSTFKAPSAVSP-----IPA 609
              ++P           DP+  A+   +   P     ++   S  KAP+  +P     +PA
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507

Query: 610  VIPSPSHKPSKTKTSKSSKVKDLSTRSDES------------------PSNKKR----KP 647
            VIPS   +   T +S+   +   +T   +                   PS KK      P
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567

Query: 648  QSSTSSSSSSSSSSLQTSLSSPLSG-PHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNG 706
            + + ++ SS  +SS      S   G P  K  ++  +    S + AP   +++  +   G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627

Query: 707  V-------SPLSAKLEPSGRTSLPGGPADIVRQVGA-VGGSSDSCPLSVPSLALHAGDLS 758
                    +P S  + PS     P  PA +  ++GA V  +S   P      AL      
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE---V 1684

Query: 759  LASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVP-DPV 817
            L +    S+  ++    +G + K SS++S    I   P   +   K P S +AP P  PV
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPDPSAKN-GSKGPLSTVAPAPLLPV 1741

Query: 818  NSTSSRQV-GKNSSLALSQSSPSSISSPGHSRQNTNRT 854
               SS+   GK++S      SP    +P  S+ +T  T
Sbjct: 1742 QKDSSKTAKGKDAS-----HSPKGPLAPPESKASTPLT 1774



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 83/337 (24%), Positives = 115/337 (34%), Gaps = 55/337 (16%)

Query: 124  SMCRPSPSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVF 183
            +M  PSP        P+ +     +K   S      ST K   +PK+ L+          
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP--------- 1602

Query: 184  PAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKP 243
            PA  S      P P       P   K         + T+  V+ SS   S  S  P    
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPE--KGPATPAPKGTPTSPPVTPSSLKDSPTS--PASVT 1658

Query: 244  VLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303
              M  +VP + + +   KG  PT + K+        + P      R+           P+
Sbjct: 1659 CKMGATVPQASKGLPAKKG--PTAL-KEVLVAPAPESTPIITAPTRK----------GPQ 1705

Query: 304  TKKP-CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREIL 362
            TKK   T    C   S  +    P        LL   K  S+  + KD  H         
Sbjct: 1706 TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASH--------- 1756

Query: 363  PSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHS---GH 419
             S  GP           + PE K ++P  +     VLP+P SA S+S++ S   S     
Sbjct: 1757 -SPKGPL----------APPESKASTPLTAAAFEKVLPKPESA-SVSAAPSPPVSLPLAP 1804

Query: 420  TPEPPLPPVGGDLASR----LSSDEGEMDGADESEKL 452
            +P P LPP    L S     L S    +  ADE E L
Sbjct: 1805 SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL 1841



 Score = 37.4 bits (85), Expect = 0.060
 Identities = 60/240 (25%), Positives = 82/240 (34%), Gaps = 28/240 (11%)

Query: 509  PPAADSPL--PSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLS-- 564
            PP+    L  PSP    TTP  A+   P   P+      AP     T   +         
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPA-ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283

Query: 565  ----NAAFVTSPDPSALMSHT----TAFPHVAATLSIMDSTFKAPSAVSPIPAVI--PSP 614
                N A VT P P    + +       P  A   S   S    P   +P P  +  PSP
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343

Query: 615  SHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPH 674
               P+   T+ SSK    +  S E P+     P      + +  S     ++ SP   P 
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 675  KKNCV------LNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLP-GGPA 727
                +        A+       A P    L    +   V+P+S K  P+  TS P GGPA
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDL----TPPAVTPVSLKKAPA--TSAPKGGPA 1457



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 82/374 (21%), Positives = 124/374 (33%), Gaps = 44/374 (11%)

Query: 382  PEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPPVGGDLASRLSSDEG 441
            PE   + P+ S PP    P     + IS +++      +P+    P     AS  +S +G
Sbjct: 728  PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC--PTEDSGASATASSKG 785

Query: 442  EMDG-ADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHL 500
             +   AD    L    S    RP      GS   G    + +          + + E  L
Sbjct: 786  TLTYLADSPSPLGVSVSPQTKRPPT--KKGSA--GPDTPIGNLSSPVSPVEASFLPENSL 841

Query: 501  NSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFS---------NPSAVYLP------- 544
            + Q  K  P    SP P       TP   + L P            PS V LP       
Sbjct: 842  SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901

Query: 545  -----SAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFK 599
                  AP  S  +SS     A  +      SP P    +   A P          S   
Sbjct: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 600  A---PSAVSPIP---AVIPSPSHKPSKTKTSKSSKVKDLSTRSDE--------SPSNKKR 645
            A   P+A  P P      PSP   P+    +  S     +T S +        +P + K 
Sbjct: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021

Query: 646  KPQSS--TSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNS 703
             P ++     +S+  +++  +   SP + P  K      ++ L S +  P   SL    +
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081

Query: 704  NNGVSPLSAKLEPS 717
                +P S K  P+
Sbjct: 1082 PPAATPPSPKGGPA 1095



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 46/184 (25%), Positives = 66/184 (35%), Gaps = 27/184 (14%)

Query: 502  SQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSA 561
            S  W   PPAA    PSP     TP P     P   P+A   P +P     T S      
Sbjct: 958  SPKWAPTPPAATP--PSPKGGPATPSPKGAPTP---PAAT--PPSPKGGPATPS----PK 1006

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAAT-LSIMDSTFKAPSAVSPIP--------AVIP 612
                   VT P P    +  T FP  A+T  +    + K   A +P+P        A +P
Sbjct: 1007 GAPTPPAVTPPSPKGSPA-ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065

Query: 613  SPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSG 672
            SP   P+      +  +K   T    +P + K  P + +   +    ++   S    L+ 
Sbjct: 1066 SPKGGPA------TPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119

Query: 673  PHKK 676
            P  K
Sbjct: 1120 PPHK 1123


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 67/301 (22%), Positives = 111/301 (36%), Gaps = 25/301 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P     T+    K     +    A +T +P  T PK+   T+  K     P + +
Sbjct: 309 PAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P  P P  + E  P   K        ++ TTT   A +T+ SA +TP    P    +
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425

Query: 249 SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDP--NKHCGVLDPETKK 306
             P +P      K   PTT  KK    T     P    + +E  P   K      P+   
Sbjct: 426 PAPTTP------KEPAPTT-PKKPAPTTPKEPAP---TTPKEPAPTTTKKPAPTTPKEPA 475

Query: 307 PCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILP-SQ 365
           P T   T  T   + ++  P   ++      E  A +  +E+       T+  E  P + 
Sbjct: 476 PTTPKETAPT---TPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTP 527

Query: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL 425
             PA  +   ++ ++  EP   +P +  P     P P++    + +T    +  T + P 
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587

Query: 426 P 426
           P
Sbjct: 588 P 588



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/326 (19%), Positives = 105/326 (32%), Gaps = 29/326 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +  +    +L   K     +    AS+T K           ++ K+      K + 
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKS 249
             P  P P  + E  P   K         + TTT   A +T+ SA +TP    P    K 
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEP-------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309

Query: 250 VPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLD----PETK 305
            P +P++        PT    K    T     P          P K          P T 
Sbjct: 310 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 369

Query: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHK-AKSREKEVKDKEHLLTSTREILPS 364
           K    + T +    + +   P   K       E     ++      KE   T+T+E  P+
Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429

Query: 365 QSGPAQDSLLGSSGSSGPE------PKVASPAKSRPPNSVLPR-----------PSSANS 407
                  +       + P+      PK  +P  ++ P    P+           P++   
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489

Query: 408 ISSSTSSNHSGHTPEPPLPPVGGDLA 433
           ++ +T    +  TPE P P    +LA
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELA 515



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/308 (22%), Positives = 109/308 (35%), Gaps = 41/308 (13%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +P     T+    K  +  +    A +T+K   T       +++K     P + S 
Sbjct: 364 PAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTT--AVSASSTSSSAVSTPPLIKPVLMS 247
                P P    E  P   K            TT    + ++T   A +TP    P    
Sbjct: 421 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480

Query: 248 KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKP 307
           ++ P +P+K      + PTT +K          KP     E E  P        PE   P
Sbjct: 481 ETAPTTPKK------LTPTTPEKL---APTTPEKPAPTTPE-ELAPT------TPEEPTP 524

Query: 308 CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREILP- 363
            T      T   + + A P   K+         A +  KE      KE   T+ +E  P 
Sbjct: 525 TTPEEPAPT---TPKAAAPNTPKE--------PAPTTPKEPAPTTPKEPAPTTPKETAPT 573

Query: 364 SQSGPAQDSLLGSSGSS--GPEPKVASPAKSRPPNSVL---PRPSSANSISSSTSSNHSG 418
           +  G A  +L   + ++   P PK  +P  ++ P S     P P++    + +T    + 
Sbjct: 574 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633

Query: 419 HTPEPPLP 426
            TP+ P P
Sbjct: 634 TTPKEPAP 641



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 29/306 (9%)

Query: 130 PSPVSPASNPRT----SLVQVKTKACLSGHHSASSTSK-PFKTPKDNLLTSSSKQHTVFP 184
           P+P +  S P T    +    K  A  +    A +T+K P  T   +  T+  +     P
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306

Query: 185 AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
            K +   P  P P    E  P   K      K  + TT    A +       T P     
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 366

Query: 245 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 304
              K   P+  K  +     PTT  +     TK++    +       +P        P T
Sbjct: 367 TTPKEPAPTTTKEPS-----PTTPKEPAPTTTKSAPTTTK-------EPAPTTTKSAPTT 414

Query: 305 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREI 361
            K  + + T +    + +   P   K+         A +  KE      KE   T+T++ 
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKK--------PAPTTPKEPAPTTPKEPAPTTTKKP 466

Query: 362 LP-SQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
            P +   PA  +   ++ ++  +    +P K  P     P P++   ++ +T    +  T
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526

Query: 421 PEPPLP 426
           PE P P
Sbjct: 527 PEEPAP 532



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 61/316 (19%), Positives = 110/316 (34%), Gaps = 30/316 (9%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P       L    TK       ++++  KP  T PK    T+  +     P + +
Sbjct: 586 PAPTTPKKPAPKELAPTTTK-----EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P    P    E  P   K   A  ++  TTT   +++++   A +TP    P    +
Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 699

Query: 249 SVPPSPEK--ILNGKGILPTTIDKKHQNGTKN----SNKPYRRLSEREFDPN-------- 294
             P +P+K      +   PTT +      TK        P     E   +P         
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759

Query: 295 KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
           K  GV  P TK P       + T K  +                 + +  A + EK  + 
Sbjct: 760 KEPGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 817

Query: 351 KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
           K  +  +T ++  + +       + +  ++   PKV +  K+     ++ +P    +   
Sbjct: 818 K--ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE-TAKPK 874

Query: 411 STSSNHSGHTPEPPLP 426
             ++N    TP+P  P
Sbjct: 875 DRATNSKATTPKPQKP 890



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 63/302 (20%), Positives = 103/302 (34%), Gaps = 44/302 (14%)

Query: 205 PNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLI---KPVLMSKSVPPSPE------ 255
           P +V   G+ +       T    S+T  + VST P I   KP+    S+PP+ +      
Sbjct: 82  PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 141

Query: 256 ------------------KILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPN--- 294
                             K  +  G   TT  K+ Q+  K S K     S+    P    
Sbjct: 142 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 201

Query: 295 ----KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREK 346
               K   +  P+   P T     S T K  + +  ++ P   K+         A +  K
Sbjct: 202 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPK 260

Query: 347 E---VKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPS 403
           E      KE   T+ +E  P+ +     +   S+ ++  EP   +P K  P     P P+
Sbjct: 261 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 320

Query: 404 SANSISSSTSSNHSGHT--PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHP 461
           +    + +T    +  T  P P  P      A +  +     + A  + K     +T  P
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380

Query: 462 RP 463
            P
Sbjct: 381 SP 382


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 67/301 (22%), Positives = 111/301 (36%), Gaps = 25/301 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P     T+    K     +    A +T +P  T PK+   T+  K     P + +
Sbjct: 350 PAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P  P P  + E  P   K        ++ TTT   A +T+ SA +TP    P    +
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466

Query: 249 SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDP--NKHCGVLDPETKK 306
             P +P      K   PTT  KK    T     P    + +E  P   K      P+   
Sbjct: 467 PAPTTP------KEPAPTT-PKKPAPTTPKEPAP---TTPKEPAPTTTKKPAPTTPKEPA 516

Query: 307 PCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILP-SQ 365
           P T   T  T   + ++  P   ++      E  A +  +E+       T+  E  P + 
Sbjct: 517 PTTPKETAPT---TPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTP 568

Query: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL 425
             PA  +   ++ ++  EP   +P +  P     P P++    + +T    +  T + P 
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628

Query: 426 P 426
           P
Sbjct: 629 P 629



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/326 (19%), Positives = 105/326 (32%), Gaps = 29/326 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +  +    +L   K     +    AS+T K           ++ K+      K + 
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKS 249
             P  P P  + E  P   K         + TTT   A +T+ SA +TP    P    K 
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEP-------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350

Query: 250 VPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLD----PETK 305
            P +P++        PT    K    T     P          P K          P T 
Sbjct: 351 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 410

Query: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHK-AKSREKEVKDKEHLLTSTREILPS 364
           K    + T +    + +   P   K       E     ++      KE   T+T+E  P+
Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470

Query: 365 QSGPAQDSLLGSSGSSGPE------PKVASPAKSRPPNSVLPR-----------PSSANS 407
                  +       + P+      PK  +P  ++ P    P+           P++   
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530

Query: 408 ISSSTSSNHSGHTPEPPLPPVGGDLA 433
           ++ +T    +  TPE P P    +LA
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELA 556



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/308 (22%), Positives = 109/308 (35%), Gaps = 41/308 (13%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +P     T+    K  +  +    A +T+K   T       +++K     P + S 
Sbjct: 405 PAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTT--AVSASSTSSSAVSTPPLIKPVLMS 247
                P P    E  P   K            TT    + ++T   A +TP    P    
Sbjct: 462 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521

Query: 248 KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKP 307
           ++ P +P+K      + PTT +K          KP     E E  P        PE   P
Sbjct: 522 ETAPTTPKK------LTPTTPEKL---APTTPEKPAPTTPE-ELAPT------TPEEPTP 565

Query: 308 CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREILP- 363
            T      T   + + A P   K+         A +  KE      KE   T+ +E  P 
Sbjct: 566 TTPEEPAPT---TPKAAAPNTPKE--------PAPTTPKEPAPTTPKEPAPTTPKETAPT 614

Query: 364 SQSGPAQDSLLGSSGSS--GPEPKVASPAKSRPPNSVL---PRPSSANSISSSTSSNHSG 418
           +  G A  +L   + ++   P PK  +P  ++ P S     P P++    + +T    + 
Sbjct: 615 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674

Query: 419 HTPEPPLP 426
            TP+ P P
Sbjct: 675 TTPKEPAP 682



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 29/306 (9%)

Query: 130 PSPVSPASNPRT----SLVQVKTKACLSGHHSASSTSK-PFKTPKDNLLTSSSKQHTVFP 184
           P+P +  S P T    +    K  A  +    A +T+K P  T   +  T+  +     P
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347

Query: 185 AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
            K +   P  P P    E  P   K      K  + TT    A +       T P     
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 407

Query: 245 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 304
              K   P+  K  +     PTT  +     TK++    +       +P        P T
Sbjct: 408 TTPKEPAPTTTKEPS-----PTTPKEPAPTTTKSAPTTTK-------EPAPTTTKSAPTT 455

Query: 305 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREI 361
            K  + + T +    + +   P   K+         A +  KE      KE   T+T++ 
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKK--------PAPTTPKEPAPTTPKEPAPTTTKKP 507

Query: 362 LP-SQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
            P +   PA  +   ++ ++  +    +P K  P     P P++   ++ +T    +  T
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567

Query: 421 PEPPLP 426
           PE P P
Sbjct: 568 PEEPAP 573



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 61/316 (19%), Positives = 110/316 (34%), Gaps = 30/316 (9%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P       L    TK       ++++  KP  T PK    T+  +     P + +
Sbjct: 627 PAPTTPKKPAPKELAPTTTK-----EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P    P    E  P   K   A  ++  TTT   +++++   A +TP    P    +
Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 740

Query: 249 SVPPSPEK--ILNGKGILPTTIDKKHQNGTKN----SNKPYRRLSEREFDPN-------- 294
             P +P+K      +   PTT +      TK        P     E   +P         
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800

Query: 295 KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
           K  GV  P TK P       + T K  +                 + +  A + EK  + 
Sbjct: 801 KEPGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 858

Query: 351 KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
           K  +  +T ++  + +       + +  ++   PKV +  K+     ++ +P    +   
Sbjct: 859 K--ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE-TAKPK 915

Query: 411 STSSNHSGHTPEPPLP 426
             ++N    TP+P  P
Sbjct: 916 DRATNSKATTPKPQKP 931



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 63/302 (20%), Positives = 103/302 (34%), Gaps = 44/302 (14%)

Query: 205 PNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLI---KPVLMSKSVPPSPE------ 255
           P +V   G+ +       T    S+T  + VST P I   KP+    S+PP+ +      
Sbjct: 123 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 182

Query: 256 ------------------KILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPN--- 294
                             K  +  G   TT  K+ Q+  K S K     S+    P    
Sbjct: 183 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 242

Query: 295 ----KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREK 346
               K   +  P+   P T     S T K  + +  ++ P   K+         A +  K
Sbjct: 243 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPK 301

Query: 347 E---VKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPS 403
           E      KE   T+ +E  P+ +     +   S+ ++  EP   +P K  P     P P+
Sbjct: 302 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 361

Query: 404 SANSISSSTSSNHSGHT--PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHP 461
           +    + +T    +  T  P P  P      A +  +     + A  + K     +T  P
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421

Query: 462 RP 463
            P
Sbjct: 422 SP 423


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 67/301 (22%), Positives = 111/301 (36%), Gaps = 25/301 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P     T+    K     +    A +T +P  T PK+   T+  K     P + +
Sbjct: 402 PAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P  P P  + E  P   K        ++ TTT   A +T+ SA +TP    P    +
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518

Query: 249 SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDP--NKHCGVLDPETKK 306
             P +P      K   PTT  KK    T     P    + +E  P   K      P+   
Sbjct: 519 PAPTTP------KEPAPTT-PKKPAPTTPKEPAP---TTPKEPAPTTTKKPAPTTPKEPA 568

Query: 307 PCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILP-SQ 365
           P T   T  T   + ++  P   ++      E  A +  +E+       T+  E  P + 
Sbjct: 569 PTTPKETAPT---TPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTP 620

Query: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL 425
             PA  +   ++ ++  EP   +P +  P     P P++    + +T    +  T + P 
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 680

Query: 426 P 426
           P
Sbjct: 681 P 681



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/326 (19%), Positives = 105/326 (32%), Gaps = 29/326 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +  +    +L   K     +    AS+T K           ++ K+      K + 
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKS 249
             P  P P  + E  P   K         + TTT   A +T+ SA +TP    P    K 
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEP-------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402

Query: 250 VPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLD----PETK 305
            P +P++        PT    K    T     P          P K          P T 
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462

Query: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHK-AKSREKEVKDKEHLLTSTREILPS 364
           K    + T +    + +   P   K       E     ++      KE   T+T+E  P+
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522

Query: 365 QSGPAQDSLLGSSGSSGPE------PKVASPAKSRPPNSVLPR-----------PSSANS 407
                  +       + P+      PK  +P  ++ P    P+           P++   
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 582

Query: 408 ISSSTSSNHSGHTPEPPLPPVGGDLA 433
           ++ +T    +  TPE P P    +LA
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELA 608



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/308 (22%), Positives = 109/308 (35%), Gaps = 41/308 (13%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +P     T+    K  +  +    A +T+K   T       +++K     P + S 
Sbjct: 457 PAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTT--AVSASSTSSSAVSTPPLIKPVLMS 247
                P P    E  P   K            TT    + ++T   A +TP    P    
Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 573

Query: 248 KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKP 307
           ++ P +P+K      + PTT +K          KP     E E  P        PE   P
Sbjct: 574 ETAPTTPKK------LTPTTPEKL---APTTPEKPAPTTPE-ELAPT------TPEEPTP 617

Query: 308 CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREILP- 363
            T      T   + + A P   K+         A +  KE      KE   T+ +E  P 
Sbjct: 618 TTPEEPAPT---TPKAAAPNTPKE--------PAPTTPKEPAPTTPKEPAPTTPKETAPT 666

Query: 364 SQSGPAQDSLLGSSGSS--GPEPKVASPAKSRPPNSVL---PRPSSANSISSSTSSNHSG 418
           +  G A  +L   + ++   P PK  +P  ++ P S     P P++    + +T    + 
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726

Query: 419 HTPEPPLP 426
            TP+ P P
Sbjct: 727 TTPKEPAP 734



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 29/306 (9%)

Query: 130 PSPVSPASNPRT----SLVQVKTKACLSGHHSASSTSK-PFKTPKDNLLTSSSKQHTVFP 184
           P+P +  S P T    +    K  A  +    A +T+K P  T   +  T+  +     P
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399

Query: 185 AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
            K +   P  P P    E  P   K      K  + TT    A +       T P     
Sbjct: 400 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459

Query: 245 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 304
              K   P+  K  +     PTT  +     TK++    +       +P        P T
Sbjct: 460 TTPKEPAPTTTKEPS-----PTTPKEPAPTTTKSAPTTTK-------EPAPTTTKSAPTT 507

Query: 305 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREI 361
            K  + + T +    + +   P   K+         A +  KE      KE   T+T++ 
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKK--------PAPTTPKEPAPTTPKEPAPTTTKKP 559

Query: 362 LP-SQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
            P +   PA  +   ++ ++  +    +P K  P     P P++   ++ +T    +  T
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619

Query: 421 PEPPLP 426
           PE P P
Sbjct: 620 PEEPAP 625



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 77/355 (21%), Positives = 124/355 (34%), Gaps = 52/355 (14%)

Query: 153 SGHHSASSTSKPFKTPKDNLLTSS-SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKAD 211
           S   S+SST +  K+ K++       K+  V   K +R K   P P       P +V   
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-KPTPK------PPVVDEA 181

Query: 212 GANVKMNSTTTTAVSASSTSSSAVSTPPLI---KPVLMSKSVPPSPE------------- 255
           G+ +       T    S+T  + VST P I   KP+    S+PP+ +             
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 241

Query: 256 -----------KILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPN-------KHC 297
                      K  +  G   TT  K+ Q+  K S K     S+    P        K  
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 301

Query: 298 GVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKD 350
            +  P+   P T     S T K  + +  ++ P   K+         A +  KE      
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTT 360

Query: 351 KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
           KE   T+ +E  P+ +     +   S+ ++  EP   +P K  P     P P++    + 
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 420

Query: 411 STSSNHSGHT--PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRP 463
           +T    +  T  P P  P      A +  +     + A  + K     +T  P P
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 61/316 (19%), Positives = 110/316 (34%), Gaps = 30/316 (9%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P       L    TK       ++++  KP  T PK    T+  +     P + +
Sbjct: 679 PAPTTPKKPAPKELAPTTTK-----EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 733

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P    P    E  P   K   A  ++  TTT   +++++   A +TP    P    +
Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792

Query: 249 SVPPSPEK--ILNGKGILPTTIDKKHQNGTKN----SNKPYRRLSEREFDPN-------- 294
             P +P+K      +   PTT +      TK        P     E   +P         
Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852

Query: 295 KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
           K  GV  P TK P       + T K  +                 + +  A + EK  + 
Sbjct: 853 KEPGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910

Query: 351 KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
           K  +  +T ++  + +       + +  ++   PKV +  K+     ++ +P    +   
Sbjct: 911 K--ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE-TAKPK 967

Query: 411 STSSNHSGHTPEPPLP 426
             ++N    TP+P  P
Sbjct: 968 DRATNSKATTPKPQKP 983



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 14/65 (21%)

Query: 614 PSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKP--------------QSSTSSSSSSSS 659
           PS K +   +  S  +K  + RS + P+ KK K               ++  SSSSSSSS
Sbjct: 73  PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132

Query: 660 SSLQT 664
           SS  T
Sbjct: 133 SSSST 137



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 56/283 (19%), Positives = 102/283 (36%), Gaps = 35/283 (12%)

Query: 596 STFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSS 655
           S+ KAP        +  +    P      K+ KV +    ++E   ++ ++  SS+SSSS
Sbjct: 74  SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133

Query: 656 SSSS-----SSLQTSLSSPLS-----GPHKKN-----------CVLNASSALNS--YQAA 692
           SSS+     SS  ++ +  L        +KKN            V  A S L++  ++  
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT 193

Query: 693 PPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLAL 752
            P  S + HN  +    ++     + R SLP   +D  ++         +      +   
Sbjct: 194 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN-SDTSKETSLTVNKETTVETKETTTTN 252

Query: 753 HAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSS-----SSKACKITKMPGMNSVHK---- 803
                        +    S +K+  K    +S      + KA   TK P + +  +    
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 312

Query: 804 --KNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 844
             K P S     P P    S+    K  +   ++S+P++   P
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 67/301 (22%), Positives = 111/301 (36%), Gaps = 25/301 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
           P+P +P     T+    K     +    A +T +P  T PK+   T+  K     P + +
Sbjct: 443 PAPTTPKEPAPTT---PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499

Query: 189 RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
              P  P P  + E  P   K        ++ TTT   A +T+ SA +TP    P    +
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559

Query: 249 SVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDP--NKHCGVLDPETKK 306
             P +P      K   PTT  KK    T     P    + +E  P   K      P+   
Sbjct: 560 PAPTTP------KEPAPTT-PKKPAPTTPKEPAP---TTPKEPAPTTTKKPAPTTPKEPA 609

Query: 307 PCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILP-SQ 365
           P T   T  T   + ++  P   ++      E  A +  +E+       T+  E  P + 
Sbjct: 610 PTTPKETAPT---TPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTP 661

Query: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPL 425
             PA  +   ++ ++  EP   +P +  P     P P++    + +T    +  T + P 
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 721

Query: 426 P 426
           P
Sbjct: 722 P 722



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/326 (19%), Positives = 105/326 (32%), Gaps = 29/326 (8%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +  +    +L   K     +    AS+T K           ++ K+      K + 
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKS 249
             P  P P  + E  P   K         + TTT   A +T+ SA +TP    P    K 
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEP-------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443

Query: 250 VPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLD----PETK 305
            P +P++        PT    K    T     P          P K          P T 
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503

Query: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHK-AKSREKEVKDKEHLLTSTREILPS 364
           K    + T +    + +   P   K       E     ++      KE   T+T+E  P+
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563

Query: 365 QSGPAQDSLLGSSGSSGPE------PKVASPAKSRPPNSVLPR-----------PSSANS 407
                  +       + P+      PK  +P  ++ P    P+           P++   
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 623

Query: 408 ISSSTSSNHSGHTPEPPLPPVGGDLA 433
           ++ +T    +  TPE P P    +LA
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELA 649



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/308 (22%), Positives = 109/308 (35%), Gaps = 41/308 (13%)

Query: 130 PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR 189
           P+P +P     T+    K  +  +    A +T+K   T       +++K     P + S 
Sbjct: 498 PAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554

Query: 190 DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTT--AVSASSTSSSAVSTPPLIKPVLMS 247
                P P    E  P   K            TT    + ++T   A +TP    P    
Sbjct: 555 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 614

Query: 248 KSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETKKP 307
           ++ P +P+K      + PTT +K          KP     E E  P        PE   P
Sbjct: 615 ETAPTTPKK------LTPTTPEKL---APTTPEKPAPTTPE-ELAPT------TPEEPTP 658

Query: 308 CTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREILP- 363
            T      T   + + A P   K+         A +  KE      KE   T+ +E  P 
Sbjct: 659 TTPEEPAPT---TPKAAAPNTPKE--------PAPTTPKEPAPTTPKEPAPTTPKETAPT 707

Query: 364 SQSGPAQDSLLGSSGSS--GPEPKVASPAKSRPPNSVL---PRPSSANSISSSTSSNHSG 418
           +  G A  +L   + ++   P PK  +P  ++ P S     P P++    + +T    + 
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767

Query: 419 HTPEPPLP 426
            TP+ P P
Sbjct: 768 TTPKEPAP 775



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 29/306 (9%)

Query: 130 PSPVSPASNPRT----SLVQVKTKACLSGHHSASSTSK-PFKTPKDNLLTSSSKQHTVFP 184
           P+P +  S P T    +    K  A  +    A +T+K P  T   +  T+  +     P
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440

Query: 185 AKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
            K +   P  P P    E  P   K      K  + TT    A +       T P     
Sbjct: 441 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500

Query: 245 LMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPET 304
              K   P+  K  +     PTT  +     TK++    +       +P        P T
Sbjct: 501 TTPKEPAPTTTKEPS-----PTTPKEPAPTTTKSAPTTTK-------EPAPTTTKSAPTT 548

Query: 305 KKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKDKEHLLTSTREI 361
            K  + + T +    + +   P   K+         A +  KE      KE   T+T++ 
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKK--------PAPTTPKEPAPTTPKEPAPTTTKKP 600

Query: 362 LP-SQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHT 420
            P +   PA  +   ++ ++  +    +P K  P     P P++   ++ +T    +  T
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660

Query: 421 PEPPLP 426
           PE P P
Sbjct: 661 PEEPAP 666



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 77/355 (21%), Positives = 124/355 (34%), Gaps = 52/355 (14%)

Query: 153 SGHHSASSTSKPFKTPKDNLLTSS-SKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKAD 211
           S   S+SST +  K+ K++       K+  V   K +R K   P P       P +V   
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-KPTPK------PPVVDEA 222

Query: 212 GANVKMNSTTTTAVSASSTSSSAVSTPPLI---KPVLMSKSVPPSPE------------- 255
           G+ +       T    S+T  + VST P I   KP+    S+PP+ +             
Sbjct: 223 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 282

Query: 256 -----------KILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPN-------KHC 297
                      K  +  G   TT  K+ Q+  K S K     S+    P        K  
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 342

Query: 298 GVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKE---VKD 350
            +  P+   P T     S T K  + +  ++ P   K+         A +  KE      
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTT 401

Query: 351 KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
           KE   T+ +E  P+ +     +   S+ ++  EP   +P K  P     P P++    + 
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 461

Query: 411 STSSNHSGHT--PEPPLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRP 463
           +T    +  T  P P  P      A +  +     + A  + K     +T  P P
Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 61/316 (19%), Positives = 110/316 (34%), Gaps = 30/316 (9%)

Query: 130  PSPVSPASNPRTSLVQVKTKACLSGHHSASSTSKPFKT-PKDNLLTSSSKQHTVFPAKGS 188
            P+P +P       L    TK       ++++  KP  T PK    T+  +     P + +
Sbjct: 720  PAPTTPKKPAPKELAPTTTK-----EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 774

Query: 189  RDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSK 248
               P    P    E  P   K   A  ++  TTT   +++++   A +TP    P    +
Sbjct: 775  PTTPKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833

Query: 249  SVPPSPEK--ILNGKGILPTTIDKKHQNGTKN----SNKPYRRLSEREFDPN-------- 294
              P +P+K      +   PTT +      TK        P     E   +P         
Sbjct: 834  PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893

Query: 295  KHCGVLDPETKKPCT----RSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKD 350
            K  GV  P TK P       + T K  +                 + +  A + EK  + 
Sbjct: 894  KEPGV--PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951

Query: 351  KEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISS 410
            K  +  +T ++  + +       + +  ++   PKV +  K+     ++ +P    +   
Sbjct: 952  K--ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE-TAKPK 1008

Query: 411  STSSNHSGHTPEPPLP 426
              ++N    TP+P  P
Sbjct: 1009 DRATNSKATTPKPQKP 1024



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 14/65 (21%)

Query: 614 PSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKP--------------QSSTSSSSSSSS 659
           PS K +   +  S  +K  + RS + P+ KK K               ++  SSSSSSSS
Sbjct: 114 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173

Query: 660 SSLQT 664
           SS  T
Sbjct: 174 SSSST 178



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 56/283 (19%), Positives = 102/283 (36%), Gaps = 35/283 (12%)

Query: 596 STFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSS 655
           S+ KAP        +  +    P      K+ KV +    ++E   ++ ++  SS+SSSS
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174

Query: 656 SSSS-----SSLQTSLSSPLS-----GPHKKN-----------CVLNASSALNS--YQAA 692
           SSS+     SS  ++ +  L        +KKN            V  A S L++  ++  
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT 234

Query: 693 PPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLAL 752
            P  S + HN  +    ++     + R SLP   +D  ++         +      +   
Sbjct: 235 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN-SDTSKETSLTVNKETTVETKETTTTN 293

Query: 753 HAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSS-----SSKACKITKMPGMNSVHK---- 803
                        +    S +K+  K    +S      + KA   TK P + +  +    
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 353

Query: 804 --KNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSP 844
             K P S     P P    S+    K  +   ++S+P++   P
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 47/256 (18%)

Query: 511 AADSPLPSPAAH-ITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFV 569
           A  +  P PA++ ++T V +S + P    S +   +  I+S  ++S   T++  S ++F+
Sbjct: 72  ATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFI 131

Query: 570 TSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKV 629
           TS       + +T+    ++T S   ST    +++S       S S   + T T+ +S  
Sbjct: 132 TSS-----FTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSN 186

Query: 630 KDLSTRSDESPSNKKRKPQSSTSSSSSS-----------SSSSLQTSLSSPLS----GPH 674
              ST +  S S       +STS+S+SS           S+S+  TS S+  S     PH
Sbjct: 187 STTSTVTSTSTSTS-----TSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPH 241

Query: 675 KKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVS------------PLSAKLEPSGRTSL 722
           +K C   AS+ L          SL V     G+             PL+ + E  G  + 
Sbjct: 242 QKQCGALASAFLFGL-------SLLVSTGTKGLGRSLVTPRPSPPPPLTPQAESGGVDAA 294

Query: 723 PGGPADIVRQVGAVGG 738
           P  P    RQV  V G
Sbjct: 295 PRAPE--TRQVRKVDG 308



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 29/132 (21%), Positives = 52/132 (39%), Gaps = 18/132 (13%)

Query: 124 SMCRPSPSPVSPASNPRTSLVQVKTKACLSGHH--------SASSTSKPFKTPKDNLLTS 175
           S  RP P+    +++  +S +       +  HH        S SS+S    T   + +TS
Sbjct: 74  SATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITS 133

Query: 176 SSKQHTVFPAKGSRDK-------PCVPVPVVSLEKIPNLVKADGANV---KMNSTTTTAV 225
           S    T   +  S              + + S   I + + +   +      NSTT+T  
Sbjct: 134 SFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVT 193

Query: 226 SASSTSSSAVST 237
           S S+++S++ ST
Sbjct: 194 STSTSTSTSTST 205


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 47/256 (18%)

Query: 511 AADSPLPSPAAH-ITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFV 569
           A  +  P PA++ ++T V +S + P    S +   +  I+S  ++S   T++  S ++F+
Sbjct: 72  ATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFI 131

Query: 570 TSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKV 629
           TS       + +T+    ++T S   ST    +++S       S S   + T T+ +S  
Sbjct: 132 TSS-----FTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSN 186

Query: 630 KDLSTRSDESPSNKKRKPQSSTSSSSSS-----------SSSSLQTSLSSPLS----GPH 674
              ST +  S S       +STS+S+SS           S+S+  TS S+  S     PH
Sbjct: 187 STTSTVTSTSTSTS-----TSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPH 241

Query: 675 KKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVS------------PLSAKLEPSGRTSL 722
           +K C   AS+ L          SL V     G+             PL+ + E  G  + 
Sbjct: 242 QKQCGALASAFLFGL-------SLLVSTGTKGLGRSLVTPRPSPPPPLTPQAESGGVDAA 294

Query: 723 PGGPADIVRQVGAVGG 738
           P  P    RQV  V G
Sbjct: 295 PRAPE--TRQVRKVDG 308



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 29/132 (21%), Positives = 52/132 (39%), Gaps = 18/132 (13%)

Query: 124 SMCRPSPSPVSPASNPRTSLVQVKTKACLSGHH--------SASSTSKPFKTPKDNLLTS 175
           S  RP P+    +++  +S +       +  HH        S SS+S    T   + +TS
Sbjct: 74  SATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITS 133

Query: 176 SSKQHTVFPAKGSRDK-------PCVPVPVVSLEKIPNLVKADGANV---KMNSTTTTAV 225
           S    T   +  S              + + S   I + + +   +      NSTT+T  
Sbjct: 134 SFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVT 193

Query: 226 SASSTSSSAVST 237
           S S+++S++ ST
Sbjct: 194 STSTSTSTSTST 205


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 79/360 (21%), Positives = 139/360 (38%), Gaps = 33/360 (9%)

Query: 508  IPPAADSPLPSPA----AHITTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTS--A 561
            +P +  +PLP+      A  + PVPAS L P    ++  +P++P++    S+ +  S  A
Sbjct: 1762 VPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPA 1821

Query: 562  MLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPSAVSPIPAVIPSPS-HKPSK 620
              S AA  +S  P++  + T     V+   S+   T  A +++  + + + S S   P+ 
Sbjct: 1822 STSAAAITSSSAPASAPAPTPILASVSTPASV---TILASASIPILASALASTSAPTPAP 1878

Query: 621  TKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVL 680
              +S ++ V    T    +P         + S   + +S+S      +P+S P   N   
Sbjct: 1879 AASSPAAPVITAPTIPASAP---------TASVPLAPASASAPAPAPTPVSAP---NPAP 1926

Query: 681  NASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSS 740
             A +   +    P  N L   + ++   P S +L PS +T  P G  D V       G S
Sbjct: 1927 PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRL-PSAQT--PNG-TDYV-----ASGKS 1977

Query: 741  DSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNS 800
               P S  +L     D  +A    ++ +          +  + S+ +K          + 
Sbjct: 1978 IQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSE 2037

Query: 801  VHKKNPPSLLAPVPDPVNSTSSRQVGKNSSL--ALSQSSPSSISSPGHSRQNTNRTGRIR 858
              K    S L    D +   +    G  + +   LS+ S   I  P   RQ   R G I+
Sbjct: 2038 GAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIK 2097



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 68/283 (24%), Positives = 110/283 (38%), Gaps = 35/283 (12%)

Query: 514  SPLPSPAAHITTPVPASVLQPFSNPSAVYLPSAPI---SSRLTS----SYIMTSAMLS-N 565
            S LP+  A   T +  +++     P+ + LP       SS LTS    ++ +T  M S  
Sbjct: 2195 SSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESAR 2254

Query: 566  AAFVTSPDPSALMSHTTAF-PHVAATLSIMDSTFKAPSAVS------------PIPAVIP 612
             A+  SP+     S  T+  P +A  +S   S+   PS  +            P+ +V P
Sbjct: 2255 KAWENSPNVREKGSPVTSTAPPIATGVS---SSASGPSTANYNSFSSASMPQIPVASVTP 2311

Query: 613  SPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSPLSG 672
            + S   + T T+ S   K  ST + + P+  K KPQ   +SS  S+S   Q S    L  
Sbjct: 2312 TASLSGAGTYTTSSLSTK--STTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIA 2369

Query: 673  PHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQ 732
              ++N  +  S +  +   A   ++  + N+ +      A+L P       G    + + 
Sbjct: 2370 QQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQH------ARLAPPSLAQQQGFQPGLSQP 2423

Query: 733  VGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKS 775
                       P+  P    H   LSL +  AVS     F  S
Sbjct: 2424 TSV---QQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSS 2463



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 66/306 (21%), Positives = 116/306 (37%), Gaps = 35/306 (11%)

Query: 552  LTSSYIMTSAMLSNAAFVTSPDPSAL--MSHTTAFPHVAATLSIMDSTFKAPSAVSPIPA 609
            L S+ +  S   S  A  ++P P+ L  +  +T+ P  A+TL+ + ++  AP   SP+  
Sbjct: 1749 LASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAP 1808

Query: 610  VIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSSSSLQTSLSSP 669
            V  S S   S   ++ ++ +      S  +P++    P    +S S+ +S ++  S S P
Sbjct: 1809 VSASASVSASVPASTSAAAI-----TSSSAPASAP-APTPILASVSTPASVTILASASIP 1862

Query: 670  LSGPHKKNCVLNASSALNSYQAAP----PYNSLSVHNSNNGVSPLSAKLEPSGRTSL--- 722
            +      +      +   S  AAP    P    S   ++  ++P SA       T +   
Sbjct: 1863 ILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAP 1922

Query: 723  ---PGGPADIVRQV-----GAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDK 774
               P  PA    Q        +  +S S     PS+ L +      +    S   +   +
Sbjct: 1923 NPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQ 1982

Query: 775  SEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLALS 834
            S G        +    K+     +N + KK  P +  P P  V++        N  L   
Sbjct: 1983 SHGTLTAELWDN----KVAPPAVLNDISKKLGP-ISPPQPPSVSAW-------NKPLTSF 2030

Query: 835  QSSPSS 840
             S+PSS
Sbjct: 2031 GSAPSS 2036



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 15/153 (9%)

Query: 112  QVFQSHCERRHGSMCRPSPSPVSP--ASNPRTSLVQVKTKACLSGHHSASSTSKPFKTPK 169
            QV Q   ++      R   S + P  A    T + Q ++ A +     AS+   P  +  
Sbjct: 1704 QVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPP--LASAPLPPSTSAS 1761

Query: 170  DNLLTSSSKQHTVFPAKGSRDKPCVPV----PVVSLEKIPNLVKADGANVKMNSTTTTAV 225
                TS+    T+ P   S   P VP     PV++    P +  +  A V  +++ + +V
Sbjct: 1762 VPASTSAPLPATLTPVPASTSAP-VPASTLAPVLASTSAP-VPASPLAPVSASASVSASV 1819

Query: 226  SASS-----TSSSAVSTPPLIKPVLMSKSVPPS 253
             AS+     TSSSA ++ P   P+L S S P S
Sbjct: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPAS 1852


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.123    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,869,607
Number of Sequences: 37866
Number of extensions: 2144410
Number of successful extensions: 20338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 782
Number of HSP's that attempted gapping in prelim test: 13642
Number of HSP's gapped (non-prelim): 5364
length of query: 861
length of database: 18,247,518
effective HSP length: 111
effective length of query: 750
effective length of database: 14,044,392
effective search space: 10533294000
effective search space used: 10533294000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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