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Search of human proteins with 16332370
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins)
isoform 8 [Homo sapiens]
(780 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1565 0.0
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1537 0.0
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1524 0.0
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 1514 0.0
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 1510 0.0
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1461 0.0
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1452 0.0
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1051 0.0
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 362 e-99
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 304 2e-82
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 303 4e-82
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 298 1e-80
gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens] 290 3e-78
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 288 1e-77
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 271 1e-72
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 270 3e-72
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 254 2e-67
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 252 8e-67
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 246 8e-65
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 246 8e-65
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 243 4e-64
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 243 4e-64
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 241 2e-63
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 240 3e-63
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 240 4e-63
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 239 5e-63
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 239 5e-63
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 234 2e-61
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 230 3e-60
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 229 1e-59
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 1565 bits (4051), Expect = 0.0
Identities = 780/780 (100%), Positives = 780/780 (100%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
Query: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR 180
ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR
Sbjct: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR 180
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
Query: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV 420
RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV
Sbjct: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV 420
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
Sbjct: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY 600
NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY
Sbjct: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY 600
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT 660
STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT
Sbjct: 601 STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT 660
Query: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
Sbjct: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
Query: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 1537 bits (3979), Expect = 0.0
Identities = 771/780 (98%), Positives = 771/780 (98%), Gaps = 9/780 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
Query: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR 180
ERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQLERKRERERKMR
Sbjct: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQLERKRERERKMR 171
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
Sbjct: 172 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 231
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
Sbjct: 232 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
Sbjct: 292 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 351
Query: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV 420
RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV
Sbjct: 352 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSV 411
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
Sbjct: 412 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 471
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
Sbjct: 472 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 531
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY 600
NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY
Sbjct: 532 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY 591
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT 660
STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT
Sbjct: 592 STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT 651
Query: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
Sbjct: 652 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 711
Query: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 712 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 771
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 1524 bits (3945), Expect = 0.0
Identities = 770/791 (97%), Positives = 770/791 (97%), Gaps = 20/791 (2%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-----------K 109
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGK 120
Query: 110 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQL 169
HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQL
Sbjct: 121 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQL 171
Query: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231
Query: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 409
NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK
Sbjct: 352 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 411
Query: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
Sbjct: 412 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 471
Query: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 529
EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI
Sbjct: 472 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 531
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR 589
QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR
Sbjct: 532 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR 591
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 649
APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG
Sbjct: 592 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 651
Query: 650 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR
Sbjct: 652 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 711
Query: 710 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 769
ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
Sbjct: 712 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 771
Query: 770 SAAGPGFSLKF 780
SAAGPGFSLKF
Sbjct: 772 SAAGPGFSLKF 782
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 1514 bits (3919), Expect = 0.0
Identities = 764/781 (97%), Positives = 765/781 (97%), Gaps = 12/781 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK KHARVKE RE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKE--RE 118
Query: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKM 179
HERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQLERKRERERKM
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQLERKRERERKM 169
Query: 180 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 239
REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE
Sbjct: 170 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 229
Query: 240 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 299
RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE
Sbjct: 230 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 289
Query: 300 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 359
EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE
Sbjct: 290 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 349
Query: 360 SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRS 419
SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCRS
Sbjct: 350 SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRS 409
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599
DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAKE
Sbjct: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 659
YSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKKM
Sbjct: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 649
Query: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 719
TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM
Sbjct: 650 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 709
Query: 720 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK 779
FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK
Sbjct: 710 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK 769
Query: 780 F 780
F
Sbjct: 770 F 770
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 1510 bits (3909), Expect = 0.0
Identities = 764/791 (96%), Positives = 765/791 (96%), Gaps = 22/791 (2%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-----------K 109
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 110 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQL 169
HARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQL
Sbjct: 121 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQL 169
Query: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
Query: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 409
NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPK
Sbjct: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 409
Query: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
Sbjct: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
Query: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 529
EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI
Sbjct: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 529
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR 589
QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYR
Sbjct: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 589
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 649
APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPG
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 649
Query: 650 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
YSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR
Sbjct: 650 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
Query: 710 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 769
ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
Sbjct: 710 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 769
Query: 770 SAAGPGFSLKF 780
SAAGPGFSLKF
Sbjct: 770 SAAGPGFSLKF 780
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 1461 bits (3781), Expect = 0.0
Identities = 733/746 (98%), Positives = 734/746 (98%), Gaps = 9/746 (1%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 154
EKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 61 EKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 120
Query: 155 GNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 214
DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR
Sbjct: 121 ---------DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 171
Query: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 274
TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 231
Query: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 334
SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 291
Query: 335 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 394
EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD
Sbjct: 292 EEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPD 351
Query: 395 SPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRL 454
SPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRL
Sbjct: 352 SPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRL 411
Query: 455 KMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMET 514
KMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMET
Sbjct: 412 KMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMET 471
Query: 515 MKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS 574
MKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS
Sbjct: 472 MKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS 531
Query: 575 PLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINK 634
PLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINK
Sbjct: 532 PLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINK 591
Query: 635 VFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPG 694
VFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPG
Sbjct: 592 VFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPG 651
Query: 695 RRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDD 754
RRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDD
Sbjct: 652 RRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDD 711
Query: 755 LKETGFHLTTTNQGASAAGPGFSLKF 780
LKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 712 LKETGFHLTTTNQGASAAGPGFSLKF 737
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 1452 bits (3759), Expect = 0.0
Identities = 733/757 (96%), Positives = 734/757 (96%), Gaps = 20/757 (2%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEK-----------KHARVKEKEREHERRKRHREEQDKARREWERQKRR 143
EKVHHRKDEKRKEK KHARVKEKEREHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRR 120
Query: 144 EMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 203
EMAREHSRRER DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER
Sbjct: 121 EMAREHSRRER---------DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 171
Query: 204 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD 263
EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD
Sbjct: 172 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD 231
Query: 264 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323
LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG
Sbjct: 232 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 291
Query: 324 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS 383
SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS
Sbjct: 292 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS 351
Query: 384 SALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDK 443
SALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDK
Sbjct: 352 SALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDK 411
Query: 444 KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNY 503
KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNY
Sbjct: 412 KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNY 471
Query: 504 VEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKV 563
VEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKV
Sbjct: 472 VEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKV 531
Query: 564 GDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 623
GDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF
Sbjct: 532 GDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 591
Query: 624 PGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFD 683
PGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFD
Sbjct: 592 PGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFD 651
Query: 684 LMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 743
LMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG
Sbjct: 652 LMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 711
Query: 744 GLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
GLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 712 GLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 748
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 1051 bits (2719), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314
MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374
EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE
Sbjct: 61 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 120
Query: 375 EVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 434
EVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY
Sbjct: 121 EVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 180
Query: 435 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 494
GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM
Sbjct: 181 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 240
Query: 495 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 554
DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL
Sbjct: 241 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 300
Query: 555 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG 614
LSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG
Sbjct: 301 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG 360
Query: 615 ELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFG 674
ELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFG
Sbjct: 361 ELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFG 420
Query: 675 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 734
ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR
Sbjct: 421 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 480
Query: 735 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 481 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 526
Score = 35.4 bits (80), Expect = 0.20
Identities = 34/146 (23%), Positives = 49/146 (33%), Gaps = 19/146 (13%)
Query: 163 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222
RD L L+ + ERK + E EE +E E S E+ +
Sbjct: 4 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 63
Query: 223 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 282
E E G + E+ EE +S+ + D ER+ +
Sbjct: 64 ----------------EEEETGSNSEEASEQSAEE---VSEEEMSEDEERENENHLLVVP 104
Query: 283 ESGSGSEEEEEEEEEEEEEGSTSEES 308
ES + E EE EEE T + S
Sbjct: 105 ESRFDRDSGESEEAEEEVGEGTPQSS 130
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 362 bits (928), Expect = e-99
Identities = 176/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
Query: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG 596
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVTLWYRAPELLLG
Sbjct: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAV 656
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP V
Sbjct: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
Query: 657 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
Query: 717 PSMFPTWPAKSEQQRVKRGTSPRPPEG 743
P + PT+P R KR +P EG
Sbjct: 332 PELMPTFP----HHRNKR-AAPATSEG 353
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 304 bits (778), Expect = 2e-82
Identities = 152/155 (98%), Positives = 152/155 (98%), Gaps = 1/155 (0%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK KHARVKEKERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
Query: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 10/139 (7%)
Query: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136
G+E DS +K ++ +++K ++EK + K R+K + +R E + + R
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIK---RLKNSDDRDSKRDSLEEGELRDHRM 58
Query: 137 WERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQ---KERE 193
+ RE S +RG + L +Q+ RK + + E++KE+R+ KE+E
Sbjct: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
Query: 194 RRAEERRKERE----ARRE 208
R E R++ RE ARRE
Sbjct: 119 REHERRKRHREEQDKARRE 137
Score = 35.4 bits (80), Expect = 0.20
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
Query: 230 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
Query: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
Score = 35.0 bits (79), Expect = 0.27
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 225
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
Query: 226 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 285
+PP++ ++EK R D +RK + E
Sbjct: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
Query: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
E + EE+++ E + E E E
Sbjct: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 303 bits (776), Expect = 4e-82
Identities = 148/288 (51%), Positives = 204/288 (70%), Gaps = 6/288 (2%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKV 635
+K TP VVTLWYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 743
R +A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 240 RATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 282
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 298 bits (763), Expect = 1e-80
Identities = 151/155 (97%), Positives = 151/155 (97%), Gaps = 3/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV--KERE 118
Query: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
Score = 37.0 bits (84), Expect = 0.070
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 11/137 (8%)
Query: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCL 161
DE +EKK + +E++ E +R K + +++D R E + R+ E + R
Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLK-NSDDRDSKRDSLEEGELRDHCMEITIRNSP------ 66
Query: 162 FRDRLEQLERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMRE 218
+R R + +E + E + + + +Q KE+ R +E+RKE+ AR + H R R
Sbjct: 67 YR-REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH 125
Query: 219 DYSDKVKASHWSRSPPR 235
W R R
Sbjct: 126 REEQDKARREWERQKRR 142
>gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens]
Length = 283
Score = 290 bits (743), Expect = 3e-78
Identities = 145/288 (50%), Positives = 200/288 (69%), Gaps = 12/288 (4%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKV 635
+K TP VVTLWYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP V + + + PYNNL+ +F LS+ G L++
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLF------ 233
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 743
+A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 234 MATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 276
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 288 bits (738), Expect = 1e-77
Identities = 137/258 (53%), Positives = 189/258 (73%), Gaps = 1/258 (0%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKV 635
+K TP VVTLWYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 696 RISAEDGLKHEYFRETPL 713
R +A D L+ YF+E PL
Sbjct: 240 RATAGDCLESSYFKEKPL 257
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 271 bits (694), Expect = 1e-72
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 270 bits (691), Expect = 3e-72
Identities = 133/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVTLWYRAPE+LLG K
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
YSTAVD+WS+GCIF E++T++ LFPG SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 254 bits (649), Expect = 2e-67
Identities = 124/297 (41%), Positives = 197/297 (66%), Gaps = 14/297 (4%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 593
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT VVTLWYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEV 174
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 653
LLG+ YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 654 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 252 bits (644), Expect = 8e-67
Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 593
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT +TLWYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 653
LLG+ YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 654 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 414
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 584 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 643
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 644 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 737 -------SPRPPEGGLGYSQLGDDD 754
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 43.9 bits (102), Expect = 6e-04
Identities = 92/443 (20%), Positives = 151/443 (34%), Gaps = 76/443 (17%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
K R + ++ + K ++ S+ S + G ++D I S R + +D G+
Sbjct: 110 KHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDR-----ISGSSKRSNEETDDYGKA 164
Query: 80 DDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE-----HERRKRHRE-EQDKA 133
K + SR K+H K KERE +R K HR+ E K+
Sbjct: 165 Q---VAKSSSKESRSSKLHKEK------------TRKERELKSGHKDRSKSHRKRETPKS 209
Query: 134 RREWERQKRREMA-----REHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQRE 188
+ + KRR + + S+++ G +D L R + K+
Sbjct: 210 YKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQD--YDLSPSRSHTSSNYDSYKKSPG 267
Query: 189 QKERERRAEERRKEREA------------RREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
R + KE A RR+ S + R S + S+ RSP
Sbjct: 268 STSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPY 327
Query: 237 PRER------FELGDGRKPV---KEEKMEERDLLSDLQDISDSERKTSSAESSSA----- 282
R R + R P+ K K R S S++K SS+ S +
Sbjct: 328 GRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPV 387
Query: 283 ----ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-----EEEEEEETGSNSEEASEQS 333
S G+E +++E + + +E + +E +S S++
Sbjct: 388 RLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKL 447
Query: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE------VGEGTPQSS--A 385
V E+ + D E N HL ++ D + +E E+ +GT S A
Sbjct: 448 PRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIA 507
Query: 386 LTEGDYVPDSPALSPIELKQELP 408
L E P S E LP
Sbjct: 508 LKEEIVTPKETETSEKETPPPLP 530
Score = 36.2 bits (82), Expect = 0.12
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 9/195 (4%)
Query: 156 NDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215
+D + DR E ER R +R R + + + + ++ E+E +EVS+ +
Sbjct: 84 SDDMAFKLDRRENDER-RGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGS 142
Query: 216 MREDYSDKVKASHWSR---SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 272
M++ S K S+ + + + K KE+ +ER+L S +D S S R
Sbjct: 143 MKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHR 202
Query: 273 KTSSAES----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
K + +S S + S S + + ++++ S S S ++ + T SN +
Sbjct: 203 KRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD-SPSGASYGQDYDLSPSRSHTSSNYDS 261
Query: 329 ASEQSAEEVSEEEMS 343
+ + +S
Sbjct: 262 YKKSPGSTSRRQSVS 276
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALSPIELKQELPKYLPAL------------ 414
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 584 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 643
+TLWYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 644 EKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 737 -------SPRPPEGGLGYSQLGDDD 754
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 43.9 bits (102), Expect = 6e-04
Identities = 92/443 (20%), Positives = 151/443 (34%), Gaps = 76/443 (17%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
K R + ++ + K ++ S+ S + G ++D I S R + +D G+
Sbjct: 110 KHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDR-----ISGSSKRSNEETDDYGKA 164
Query: 80 DDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE-----HERRKRHRE-EQDKA 133
K + SR K+H K KERE +R K HR+ E K+
Sbjct: 165 Q---VAKSSSKESRSSKLHKEK------------TRKERELKSGHKDRSKSHRKRETPKS 209
Query: 134 RREWERQKRREMA-----REHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQRE 188
+ + KRR + + S+++ G +D L R + K+
Sbjct: 210 YKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQD--YDLSPSRSHTSSNYDSYKKSPG 267
Query: 189 QKERERRAEERRKEREA------------RREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
R + KE A RR+ S + R S + S+ RSP
Sbjct: 268 STSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPY 327
Query: 237 PRER------FELGDGRKPV---KEEKMEERDLLSDLQDISDSERKTSSAESSSA----- 282
R R + R P+ K K R S S++K SS+ S +
Sbjct: 328 GRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPV 387
Query: 283 ----ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE-----EEEEEEETGSNSEEASEQS 333
S G+E +++E + + +E + +E +S S++
Sbjct: 388 RLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKL 447
Query: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE------VGEGTPQSS--A 385
V E+ + D E N HL ++ D + +E E+ +GT S A
Sbjct: 448 PRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIA 507
Query: 386 LTEGDYVPDSPALSPIELKQELP 408
L E P S E LP
Sbjct: 508 LKEEIVTPKETETSEKETPPPLP 530
Score = 36.2 bits (82), Expect = 0.12
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 9/195 (4%)
Query: 156 NDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215
+D + DR E ER R +R R + + + + ++ E+E +EVS+ +
Sbjct: 84 SDDMAFKLDRRENDER-RGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGS 142
Query: 216 MREDYSDKVKASHWSR---SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 272
M++ S K S+ + + + K KE+ +ER+L S +D S S R
Sbjct: 143 MKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHR 202
Query: 273 KTSSAES----SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
K + +S S + S S + + ++++ S S S ++ + T SN +
Sbjct: 203 KRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD-SPSGASYGQDYDLSPSRSHTSSNYDS 261
Query: 329 ASEQSAEEVSEEEMS 343
+ + +S
Sbjct: 262 YKKSPGSTSRRQSVS 276
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 243 bits (621), Expect = 4e-64
Identities = 209/777 (26%), Positives = 332/777 (42%), Gaps = 87/777 (11%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRK-------DEKRKEKKHARVKEKER------- 118
Q R K + R+ +R+ ++R ER
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 119 ---EHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRER 175
R+ RR + + R + HSR R R +L R R R
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRS----------RSR-HRLSRSRSR 434
Query: 176 ERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR 235
+ + E ++ + EA R A ++ + + +
Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494
Query: 236 PPRERFELGDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGS 288
P + E K VK+ K+E S + + + KT + + E+
Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIV 554
Query: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE-------- 340
++ ++ +E ++ EE +E+ + T S + EQ V+
Sbjct: 555 DKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPP 614
Query: 341 EMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP---- 396
+ ED+E ++ + V + E E+ + P L GD + SP
Sbjct: 615 MLPEDKEADSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKK 669
Query: 397 ALSPIELKQEL----PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDE 447
+ + K+ P+Y + G R V++F + I EGTYG VY+A+DK T E
Sbjct: 670 TATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGE 729
Query: 448 IVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYI 499
+VALK+++++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+
Sbjct: 730 MVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYL 789
Query: 500 VMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAG 559
V Y++HDL L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G
Sbjct: 790 VFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRG 849
Query: 560 ILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
+K+ DFGLAR Y S + YT V+TLWYR PELLLG + Y+ A+D+WS GCI GEL T
Sbjct: 850 QIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 909
Query: 619 QKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLS 678
+KP+F E+ Q+ + + G+P +WP +LP M + LR+ F +
Sbjct: 910 KKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIP 968
Query: 679 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 734
DL + L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 969 AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 37.0 bits (84), Expect = 0.070
Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 11/155 (7%)
Query: 93 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHR----EEQDKARREWERQKRREMARE 148
R+ + R+ + + R KE+ REH RR R + ++R ++R E+A+
Sbjct: 189 RRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 149 HSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQRE----QKERERRAEERRKERE 204
S G RK + R + K +E KE + E + E +
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 205 A-RREVSAHHRTMRED--YSDKVKASHWSRSPPRP 236
A RR S R+D S + S SR P P
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSP 343
Score = 32.0 bits (71), Expect = 2.3
Identities = 50/249 (20%), Positives = 78/249 (31%), Gaps = 27/249 (10%)
Query: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR 180
+RR E + + R + +E REH RR+ G + R ER +
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
+ + A R+ AH + S K S + + PP+ RE
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTK---SSKEPPSAY-KEPPKAYRE- 302
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
D +P + L D S R + S S + S +G
Sbjct: 303 ----DKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG------------ 346
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
GS+ + S S +S + +VS S R + + P S
Sbjct: 347 -GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYS 400
Query: 361 RFDRDSGES 369
R SG+S
Sbjct: 401 PVLRRSGKS 409
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 243 bits (621), Expect = 4e-64
Identities = 209/777 (26%), Positives = 332/777 (42%), Gaps = 87/777 (11%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRK-------DEKRKEKKHARVKEKER------- 118
Q R K + R+ +R+ ++R ER
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 119 ---EHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRER 175
R+ RR + + R + HSR R R +L R R R
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRS----------RSR-HRLSRSRSR 434
Query: 176 ERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPR 235
+ + E ++ + EA R A ++ + + +
Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494
Query: 236 PPRERFELGDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGS 288
P + E K VK+ K+E S + + + KT + + E+
Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIV 554
Query: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE-------- 340
++ ++ +E ++ EE +E+ + T S + EQ V+
Sbjct: 555 DKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPP 614
Query: 341 EMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP---- 396
+ ED+E ++ + V + E E+ + P L GD + SP
Sbjct: 615 MLPEDKEADSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKK 669
Query: 397 ALSPIELKQEL----PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDE 447
+ + K+ P+Y + G R V++F + I EGTYG VY+A+DK T E
Sbjct: 670 TATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGE 729
Query: 448 IVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYI 499
+VALK+++++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+
Sbjct: 730 MVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYL 789
Query: 500 VMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAG 559
V Y++HDL L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G
Sbjct: 790 VFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRG 849
Query: 560 ILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
+K+ DFGLAR Y S + YT V+TLWYR PELLLG + Y+ A+D+WS GCI GEL T
Sbjct: 850 QIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 909
Query: 619 QKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLS 678
+KP+F E+ Q+ + + G+P +WP +LP M + LR+ F +
Sbjct: 910 KKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIP 968
Query: 679 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 734
DL + L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 969 AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 37.0 bits (84), Expect = 0.070
Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 11/155 (7%)
Query: 93 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHR----EEQDKARREWERQKRREMARE 148
R+ + R+ + + R KE+ REH RR R + ++R ++R E+A+
Sbjct: 189 RRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 149 HSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQRE----QKERERRAEERRKERE 204
S G RK + R + K +E KE + E + E +
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPK 308
Query: 205 A-RREVSAHHRTMRED--YSDKVKASHWSRSPPRP 236
A RR S R+D S + S SR P P
Sbjct: 309 AYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSP 343
Score = 32.0 bits (71), Expect = 2.3
Identities = 50/249 (20%), Positives = 78/249 (31%), Gaps = 27/249 (10%)
Query: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMR 180
+RR E + + R + +E REH RR+ G + R ER +
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
+ + A R+ AH + S K S + + PP+ RE
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTK---SSKEPPSAY-KEPPKAYRE- 302
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
D +P + L D S R + S S + S +G
Sbjct: 303 ----DKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG------------ 346
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
GS+ + S S +S + +VS S R + + P S
Sbjct: 347 -GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYS 400
Query: 361 RFDRDSGES 369
R SG+S
Sbjct: 401 PVLRRSGKS 409
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 241 bits (614), Expect = 2e-63
Identities = 125/295 (42%), Positives = 183/295 (62%), Gaps = 6/295 (2%)
Query: 416 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTIL 475
G +E + L ++ EGTY VY+ + K T+ +VALK +++E E EG P T++RE++ +
Sbjct: 185 GFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLK 243
Query: 476 KAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRG 534
+H NIVT+ +IV + DK + +V Y++ DLK M+ VK + Q+LRG
Sbjct: 244 DLKHANIVTLHDIV---HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG 300
Query: 535 VKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 594
+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+ VVTLWYR P++L
Sbjct: 301 LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL 360
Query: 595 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELP 654
LG+ EYST +DMW VGCIF E+ + +PLFPG + D+++ +F+ LGTPS++ WPG S
Sbjct: 361 LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE 420
Query: 655 AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
K F ++ L L +G +L+ KFL Y +R+SAE+ +KH YFR
Sbjct: 421 EFKNYNFPKYKPQPLINH-APRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFR 474
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 240 bits (613), Expect = 3e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 477
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 537
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
Query: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 597
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
Query: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 657
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
Query: 658 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
Query: 718 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 745
P P ++ +++ +KR + +GGL
Sbjct: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 240 bits (612), Expect = 4e-63
Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI + + +H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
NIV + +++ K+ +V + + DLK ++ P VK+ + QLL+G+ H
Sbjct: 61 KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599
+LHRDLK NLL++ G LK+ DFGLAR +G P++ Y+ VVTLWYR P++L GAK
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 600 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
YST++DMWS GCIF EL +PLFPG DQ+ ++F+ LGTP+E+ WP ++LP K
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
+ +P L+ G DL+ L P +RISAE+ L+H YF +
Sbjct: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 239 bits (611), Expect = 5e-63
Identities = 159/463 (34%), Positives = 236/463 (50%), Gaps = 25/463 (5%)
Query: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 41 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 100
Query: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPI- 401
S R NH P + +E+ + + P L EG Y+ SPI
Sbjct: 101 SPVRVRMR-NH----PPRKIS-----TEDINKRLS--LPADIRLPEG-YLEKLTLNSPIF 147
Query: 402 --ELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 459
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E
Sbjct: 148 DKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE 207
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF 519
EG P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 208 -EGAPCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNII 264
Query: 520 LPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY 579
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y
Sbjct: 265 NMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY 324
Query: 580 TPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDL 639
+ VVTLWYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG + +Q++ +F+ L
Sbjct: 325 SNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRIL 384
Query: 640 GTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 699
GTP+E+ WPG K + ++ L L SD G DL+ K L + RISA
Sbjct: 385 GTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISA 443
Query: 700 EDGLKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 737
ED +KH +F R LP S+F + +++ R +S
Sbjct: 444 EDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 486
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 239 bits (611), Expect = 5e-63
Identities = 159/463 (34%), Positives = 236/463 (50%), Gaps = 25/463 (5%)
Query: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 35 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 94
Query: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPI- 401
S R NH P + +E+ + + P L EG Y+ SPI
Sbjct: 95 SPVRVRMR-NH----PPRKIS-----TEDINKRLS--LPADIRLPEG-YLEKLTLNSPIF 141
Query: 402 --ELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 459
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E
Sbjct: 142 DKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE 201
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF 519
EG P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 202 -EGAPCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNII 258
Query: 520 LPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY 579
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y
Sbjct: 259 NMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY 318
Query: 580 TPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDL 639
+ VVTLWYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG + +Q++ +F+ L
Sbjct: 319 SNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRIL 378
Query: 640 GTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 699
GTP+E+ WPG K + ++ L L SD G DL+ K L + RISA
Sbjct: 379 GTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISA 437
Query: 700 EDGLKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 737
ED +KH +F R LP S+F + +++ R +S
Sbjct: 438 EDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 480
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 234 bits (598), Expect = 2e-61
Identities = 127/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
++++ L RI EG +G+V++AK +T EIVALK++ + + ++GFP +LREI L+
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
N V+ V + + ++ DL ++ ++P +VK+ + LL+GV H
Sbjct: 60 DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAK 598
N I+HRDLK +NLL+S +G LK+ DFGLAR + + YT V T WYRAPELL GA+
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
+Y VD+WSVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++WP +ELP K
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718
++F E L + +S Q DL+ +FL Y P +RI+A L H+YF PLP PS
Sbjct: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
Query: 719 MFP 721
P
Sbjct: 299 ELP 301
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 230 bits (587), Expect = 3e-60
Identities = 122/294 (41%), Positives = 176/294 (59%), Gaps = 5/294 (1%)
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
+ ++ L ++ EG+Y VY+ K K ++VALK +++++E EG P T++RE + + +H
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHA 173
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIV + +I+ + + +V YV DL M+ P VK + QLLRG+ ++H
Sbjct: 174 NIVLLHDII--HTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQ 231
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY 600
+ILHRDLK NLL+S G LK+ DFGLAR P Y+ VVTLWYR P++LLG+ EY
Sbjct: 232 RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY 291
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGKSEI-DQINKVFKDLGTPSEKIWPGYSELPAVKKM 659
ST +DMW VGCIF E++ FPG +I DQ+ ++F LGTP+E WPG LP K
Sbjct: 292 STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE 351
Query: 660 TFSEHPYNNLRKRFGAL-LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 712
F+ + NLR+ + L + DL +K L P R+SA+ L HEYF + P
Sbjct: 352 RFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 229 bits (583), Expect = 1e-59
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 475
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
Query: 476 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 528
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
Query: 529 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 588
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
Query: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 648
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
Query: 649 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
Query: 709 RE 710
++
Sbjct: 301 QD 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,012,218
Number of Sequences: 37866
Number of extensions: 1978639
Number of successful extensions: 133699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2506
Number of HSP's successfully gapped in prelim test: 1544
Number of HSP's that attempted gapping in prelim test: 18597
Number of HSP's gapped (non-prelim): 33302
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.