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Search of human proteins with 159032537
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|159032537 FERM, RhoGEF, and pleckstrin domain protein 1
isoform 2 [Homo sapiens]
(129 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|159032537 FERM, RhoGEF, and pleckstrin domain protein 1 isofo... 263 3e-71
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 117 2e-27
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 44 4e-05
gi|116734704 interferon regulatory factor 2 binding protein 2 is... 31 0.31
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 30 0.53
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 30 0.53
gi|116734706 interferon regulatory factor 2 binding protein 2 is... 30 0.69
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 29 0.90
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 29 0.90
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 29 0.90
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 29 0.90
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 28 1.5
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 28 2.6
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 27 3.4
gi|239754991 PREDICTED: hypothetical protein isoform 1 [Homo sap... 27 4.5
gi|169166960 PREDICTED: hypothetical protein [Homo sapiens] 27 4.5
gi|169166769 PREDICTED: hypothetical protein [Homo sapiens] 27 4.5
gi|169166416 PREDICTED: hypothetical protein [Homo sapiens] 27 4.5
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 27 4.5
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 26 7.6
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 26 7.6
gi|205360981 resistance to inhibitors of cholinesterase 3 homolo... 26 7.6
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 26 7.6
gi|24307933 transcription factor EB [Homo sapiens] 26 7.6
gi|144922720 coiled-coil domain containing 15 [Homo sapiens] 26 7.6
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 26 9.9
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 26 9.9
gi|241896898 family with sequence similarity 20, member A [Homo ... 26 9.9
gi|239753439 PREDICTED: hypothetical protein [Homo sapiens] 26 9.9
gi|239748004 PREDICTED: hypothetical protein [Homo sapiens] 26 9.9
>gi|159032537 FERM, RhoGEF, and pleckstrin domain protein 1 isoform
2 [Homo sapiens]
Length = 129
Score = 263 bits (672), Expect = 3e-71
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPMVS 60
MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPMVS
Sbjct: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPMVS 60
Query: 61 SSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFGEDRILTHLTGSISYTNWAGSRSLAVT 120
SSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFGEDRILTHLTGSISYTNWAGSRSLAVT
Sbjct: 61 SSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFGEDRILTHLTGSISYTNWAGSRSLAVT 120
Query: 121 VTEELLNLF 129
VTEELLNLF
Sbjct: 121 VTEELLNLF 129
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform
1 [Homo sapiens]
Length = 1045
Score = 117 bits (294), Expect = 2e-27
Identities = 57/57 (100%), Positives = 57/57 (100%)
Query: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVP 57
MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVP
Sbjct: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVP 57
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 43.9 bits (102), Expect = 4e-05
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 1 MGEIEQR----PTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 56
MGEIE T G RLGA G+STLE GQ P K + +++++LD+T E F++
Sbjct: 1 MGEIEGTYRVLQTAGMRLGAQTPVGVSTLEPGQTLLPRMQEKHLHLRVKLLDNTMEIFDI 60
>gi|116734704 interferon regulatory factor 2 binding protein 2
isoform A [Homo sapiens]
Length = 587
Score = 30.8 bits (68), Expect = 0.31
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 15 GAPENSGISTLERGQKPPPTPSGKLVSIKIQ-----MLDDTQEAFEVPMVSSSSFL 65
GA + ++ R +KP P P G++ KI L + E ++PM +SSF+
Sbjct: 343 GANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFV 398
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 30.0 bits (66), Expect = 0.53
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 3 EIEQRPTPGSRLGAPENSGISTLE--RGQKPPPTPS 36
E ++RP PGSR GAP +SG S+ +G P+P+
Sbjct: 14 ERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPA 49
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 30.0 bits (66), Expect = 0.53
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 3 EIEQRPTPGSRLGAPENSGISTLE--RGQKPPPTPS 36
E ++RP PGSR GAP +SG S+ +G P+P+
Sbjct: 14 ERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPA 49
>gi|116734706 interferon regulatory factor 2 binding protein 2
isoform B [Homo sapiens]
Length = 571
Score = 29.6 bits (65), Expect = 0.69
Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 17 PENSGISTLERGQKPPPTPSGKLVSIKIQ-----MLDDTQEAFEVPMVSSSSFL 65
P + ++ R +KP P P G++ KI L + E ++PM +SSF+
Sbjct: 329 PALTAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFV 382
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 29.3 bits (64), Expect = 0.90
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 12/101 (11%)
Query: 6 QRPTPGSRLGAPENSGIS-----TLERGQKPPPTPS-------GKLVSIKIQMLDDTQEA 53
QR +PG GA ++ T G P S G+ S +Q L+ +
Sbjct: 34 QRKSPGIPAGANRKKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQE 93
Query: 54 FEVPMVSSSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFG 94
V + SSS+ + + V + KH HL++K G
Sbjct: 94 LAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 29.3 bits (64), Expect = 0.90
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 12/101 (11%)
Query: 6 QRPTPGSRLGAPENSGIS-----TLERGQKPPPTPS-------GKLVSIKIQMLDDTQEA 53
QR +PG GA ++ T G P S G+ S +Q L+ +
Sbjct: 34 QRKSPGIPAGANRKKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQE 93
Query: 54 FEVPMVSSSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFG 94
V + SSS+ + + V + KH HL++K G
Sbjct: 94 LAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 29.3 bits (64), Expect = 0.90
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 12/101 (11%)
Query: 6 QRPTPGSRLGAPENSGIS-----TLERGQKPPPTPS-------GKLVSIKIQMLDDTQEA 53
QR +PG GA ++ T G P S G+ S +Q L+ +
Sbjct: 34 QRKSPGIPAGANRKKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQE 93
Query: 54 FEVPMVSSSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFG 94
V + SSS+ + + V + KH HL++K G
Sbjct: 94 LAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 29.3 bits (64), Expect = 0.90
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 12/101 (11%)
Query: 6 QRPTPGSRLGAPENSGIS-----TLERGQKPPPTPS-------GKLVSIKIQMLDDTQEA 53
QR +PG GA ++ T G P S G+ S +Q L+ +
Sbjct: 34 QRKSPGIPAGANRKKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQE 93
Query: 54 FEVPMVSSSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFG 94
V + SSS+ + + V + KH HL++K G
Sbjct: 94 LAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 28.5 bits (62), Expect = 1.5
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 12/101 (11%)
Query: 6 QRPTPGSRLGAPENSGIS-----TLERGQKPPPTPS-------GKLVSIKIQMLDDTQEA 53
QR +PG GA I+ T G P S G+ S ++ L+ +
Sbjct: 34 QRKSPGIPAGANRKKKINGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLEDLESQYQE 93
Query: 54 FEVPMVSSSSFLKATGSSWTGWVLRCSMKPKHHSHLIEKFG 94
V + SSS+ + + V + KH HL++K G
Sbjct: 94 LAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLG 134
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 27.7 bits (60), Expect = 2.6
Identities = 13/40 (32%), Positives = 19/40 (47%)
Query: 4 IEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIK 43
+E P R GAP +RG+ PP+P G S++
Sbjct: 3131 LETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVE 3170
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 27.3 bits (59), Expect = 3.4
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Query: 1 MGEIEQRPTPGS--RLGAPENSGISTLERGQKPPPTPSGKLV 40
+GE + PG R G+P +SG +RG+ PP P G+LV
Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKG-DRGEPGPPGPPGRLV 1709
>gi|239754991 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 209
Score = 26.9 bits (58), Expect = 4.5
Identities = 11/30 (36%), Positives = 15/30 (50%)
Query: 8 PTPGSRLGAPENSGISTLERGQKPPPTPSG 37
P P +R AP + + + PPP PSG
Sbjct: 128 PRPAARRAAPSSPAVPREGQRAAPPPRPSG 157
>gi|169166960 PREDICTED: hypothetical protein [Homo sapiens]
Length = 216
Score = 26.9 bits (58), Expect = 4.5
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 8 PTPGSRLGAPENSGISTLERG-QKPPPTPS 36
PT G+R P + L+RG Q+PPPTPS
Sbjct: 130 PTLGARPRRPTWPPRAQLKRGDQQPPPTPS 159
>gi|169166769 PREDICTED: hypothetical protein [Homo sapiens]
Length = 216
Score = 26.9 bits (58), Expect = 4.5
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 8 PTPGSRLGAPENSGISTLERG-QKPPPTPS 36
PT G+R P + L+RG Q+PPPTPS
Sbjct: 130 PTLGARPRRPTWPPRAQLKRGDQQPPPTPS 159
>gi|169166416 PREDICTED: hypothetical protein [Homo sapiens]
Length = 216
Score = 26.9 bits (58), Expect = 4.5
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 8 PTPGSRLGAPENSGISTLERG-QKPPPTPS 36
PT G+R P + L+RG Q+PPPTPS
Sbjct: 130 PTLGARPRRPTWPPRAQLKRGDQQPPPTPS 159
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 26.9 bits (58), Expect = 4.5
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 4/106 (3%)
Query: 8 PTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQML-DDTQEAFEVPMVSSSSFLK 66
P P SR +PE + + + P P + + ++L D QE P+VS +L
Sbjct: 1524 PQPCSRPASPEPELLPEADSKKLPSPARATETDKEPQRLLVPDIQEIRVSPIVSKKGYLH 1583
Query: 67 ATGSSWTGWVLRCSM--KPKHHSHLIEKFGEDRILTHL-TGSISYT 109
+GW R + +P + + +K +R + +L T + Y+
Sbjct: 1584 FLEPHTSGWARRFVVVRRPYAYMYNSDKDTVERFVLNLATAQVEYS 1629
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 26.2 bits (56), Expect = 7.6
Identities = 11/22 (50%), Positives = 12/22 (54%)
Query: 15 GAPENSGISTLERGQKPPPTPS 36
G P + G T E G P PTPS
Sbjct: 173 GIPSSPGAHTTEAGTLPAPTPS 194
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 26.2 bits (56), Expect = 7.6
Identities = 11/22 (50%), Positives = 12/22 (54%)
Query: 15 GAPENSGISTLERGQKPPPTPS 36
G P + G T E G P PTPS
Sbjct: 173 GIPSSPGAHTTEAGTLPAPTPS 194
>gi|205360981 resistance to inhibitors of cholinesterase 3 homolog
isoform a [Homo sapiens]
Length = 368
Score = 26.2 bits (56), Expect = 7.6
Identities = 12/17 (70%), Positives = 13/17 (76%), Gaps = 2/17 (11%)
Query: 25 LERG--QKPPPTPSGKL 39
L RG Q+PPPTP GKL
Sbjct: 28 LSRGKRQEPPPTPEGKL 44
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 26.2 bits (56), Expect = 7.6
Identities = 14/53 (26%), Positives = 23/53 (43%)
Query: 2 GEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAF 54
G++ P P +R E S S P P G+L + + ++DD + F
Sbjct: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKF 423
>gi|24307933 transcription factor EB [Homo sapiens]
Length = 476
Score = 26.2 bits (56), Expect = 7.6
Identities = 13/46 (28%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 5 EQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDT 50
+Q+ +LG P I+T Q PPP P G+++ ++ + + T
Sbjct: 36 QQQQQQQQQLGGPPTPAINTPVHFQSPPPVP-GEVLKVQSYLENPT 80
>gi|144922720 coiled-coil domain containing 15 [Homo sapiens]
Length = 951
Score = 26.2 bits (56), Expect = 7.6
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 17 PENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEA-FEVPMVSSSSFL 65
P ++GI+T RG+ P G L ++ Q + QE +E P SS L
Sbjct: 217 PASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSL 266
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 25.8 bits (55), Expect = 9.9
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTP 35
+GE+ P+P R GAP S + +PP P
Sbjct: 431 LGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKP 465
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 25.8 bits (55), Expect = 9.9
Identities = 12/35 (34%), Positives = 17/35 (48%)
Query: 1 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTP 35
+GE+ P+P R GAP S + +PP P
Sbjct: 338 LGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKP 372
>gi|241896898 family with sequence similarity 20, member A [Homo
sapiens]
Length = 541
Score = 25.8 bits (55), Expect = 9.9
Identities = 9/19 (47%), Positives = 12/19 (63%)
Query: 84 KHHSHLIEKFGEDRILTHL 102
+HH + KFG+D L HL
Sbjct: 411 RHHYEMFTKFGDDGFLIHL 429
>gi|239753439 PREDICTED: hypothetical protein [Homo sapiens]
Length = 144
Score = 25.8 bits (55), Expect = 9.9
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 11/74 (14%)
Query: 16 APENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPMVSSSSFLKATGSSWTGW 75
AP +S L R QKP +PS K TQ ++S S + ++ W
Sbjct: 16 APSSSRHLQLWRHQKPLSSPSAK-----------TQSTPSASLLSGVSVWEWEAAASQSW 64
Query: 76 VLRCSMKPKHHSHL 89
VLR + H L
Sbjct: 65 VLRAQCFTETHRRL 78
>gi|239748004 PREDICTED: hypothetical protein [Homo sapiens]
Length = 144
Score = 25.8 bits (55), Expect = 9.9
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 11/74 (14%)
Query: 16 APENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPMVSSSSFLKATGSSWTGW 75
AP +S L R QKP +PS K TQ ++S S + ++ W
Sbjct: 16 APSSSRHLQLWRHQKPLSSPSAK-----------TQSTPSASLLSGVSVWEWEAAASQSW 64
Query: 76 VLRCSMKPKHHSHL 89
VLR + H L
Sbjct: 65 VLRAQCFTETHRRL 78
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,974,583
Number of Sequences: 37866
Number of extensions: 279545
Number of successful extensions: 816
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 795
Number of HSP's gapped (non-prelim): 39
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.