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Search of human proteins with 158187521
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|158187521 A-kinase anchor protein 5 [Homo sapiens]
(427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|158187521 A-kinase anchor protein 5 [Homo sapiens] 827 0.0
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 54 3e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 54 3e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 4e-05
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 46 7e-05
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 46 7e-05
gi|104526627 triadin [Homo sapiens] 45 1e-04
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 43 5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 43 5e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 42 8e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 42 8e-04
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 42 0.001
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 41 0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.003
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.003
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.003
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.003
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.003
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.003
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.003
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.003
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 40 0.005
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 39 0.012
gi|5729734 activator of S phase kinase [Homo sapiens] 39 0.012
gi|157738619 smoothelin-like 1 [Homo sapiens] 39 0.012
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 38 0.015
gi|34878777 ring finger protein 20 [Homo sapiens] 38 0.020
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.026
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 37 0.026
>gi|158187521 A-kinase anchor protein 5 [Homo sapiens]
Length = 427
Score = 827 bits (2136), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR
Sbjct: 1 METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
Query: 61 KCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKK 120
KCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKK
Sbjct: 61 KCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKK 120
Query: 121 AKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQ 180
AKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQ
Sbjct: 121 AKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQ 180
Query: 181 DLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQ 240
DLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQ
Sbjct: 181 DLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQ 240
Query: 241 DVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIV 300
DVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIV
Sbjct: 241 DVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIV 300
Query: 301 AEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPK 360
AEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPK
Sbjct: 301 AEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPK 360
Query: 361 QFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDN 420
QFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDN
Sbjct: 361 QFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDN 420
Query: 421 KINNLLQ 427
KINNLLQ
Sbjct: 421 KINNLLQ 427
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 53.9 bits (128), Expect = 3e-07
Identities = 74/354 (20%), Positives = 146/354 (41%), Gaps = 57/354 (16%)
Query: 11 ENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASD 70
++ ++K+S G+ G E+ KR K K+ + + ++D + +E G +
Sbjct: 1037 DSSEDKKSKNGAYGREK----------KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNS 1086
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLS-----KKKAKSRL 125
+ LKR+ R +R+ SSK+ E+Q ++ DA+ S KKK ++
Sbjct: 1087 SDK-------RLKRIELRERRNLSSKRNTK---EIQSGSSSSDAEESSEDNKKKKQRTSS 1136
Query: 126 KIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEG 185
K + + KR++ + I ++I D Q + + ++ + + ++E
Sbjct: 1137 KKKAV-IVKEKKRNSLRTSTKRKQADITSSSSSDIED-DDQNSIGEGSSDEQKIKPVTEN 1194
Query: 186 ISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQ 245
+ C+S+ + + V + DN ++LEEI+ +
Sbjct: 1195 LVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSS 1254
Query: 246 QASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAP------------NGKD 293
P E + +Q ++ P Q+ E+ + + ES D
Sbjct: 1255 DDEPEEGKKRTGKQ---NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSD 1311
Query: 294 YESTEIVAEETKPKD-------------TELSQESDFKENGITEEKSKSEESKR 334
ES E ++TKPK+ +E S++SDF+E+G++EE S+SE+ +R
Sbjct: 1312 GESGE--EKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1363
Score = 36.2 bits (82), Expect = 0.058
Identities = 85/455 (18%), Positives = 161/455 (35%), Gaps = 59/455 (12%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRR-----------KKAAKALKPKAGS---EAADV 58
K E++ S G E+ E+ + F + +K +K ++ K E +D
Sbjct: 966 KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1025
Query: 59 ARKCPQEAGASDQPEPTR---GAWASLKRLV-----TRRKRSESSKQQKPLEGEMQPAIN 110
A K + + D E + GA+ K+ + RKR + S + N
Sbjct: 1026 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1085
Query: 111 AEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLN 170
+ D L + + + R + + + + + S E+S K +++ +T +
Sbjct: 1086 SSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ------RTSSKKK 1139
Query: 171 DQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLIL 230
K K L RK D + S+ S+ + I + + ++
Sbjct: 1140 AVIVKEKKRNSLRTSTKRKQAD-ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1198
Query: 231 EEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPN 290
+ D ++ P+ + D D P I + ++EE +
Sbjct: 1199 SHTGFCQSSGDEALSKSVPVTVDDDD------DDNDPENRIAKKMLLEEIKANLSSDEDG 1252
Query: 291 GKDYESTEIVAE-----ETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDT 345
D E E E P D E + + + + +EE K R+ + ++D
Sbjct: 1253 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1312
Query: 346 EISEFDVTKSKNVPK-----QFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASS-- 398
E E TK K + + +S+E+ + F ++G + SE + T S+
Sbjct: 1313 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDF-QESGVSEEVSESEDEQRPRTRSAKK 1371
Query: 399 --LVKNAIQLSIEQ-------LVNEMASDDNKINN 424
L +N Q S +Q V E +S +NK N+
Sbjct: 1372 AELEEN--QRSYKQKKKRRRIKVQEDSSSENKSNS 1404
Score = 31.6 bits (70), Expect = 1.4
Identities = 62/305 (20%), Positives = 115/305 (37%), Gaps = 59/305 (19%)
Query: 88 RRKRSESSKQQKPLEGEMQPAINAEDADLSKK-KAKSRLKIPCIKFPR---------GPK 137
R R +++ ++P E P + D + ++ K K +L +P K + PK
Sbjct: 617 RSPRVKTTPLRRPTE--TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK 674
Query: 138 -----RSNHSKIIE---DSDCSIKVQEEAEILD--IQTQTPLNDQATKAKSTQDLSEGIS 187
+S S+ ++ DSD + + +E + + T +N+ T K+ DL
Sbjct: 675 PNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAG 734
Query: 188 RKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQA 247
+ D + S+TSG + G SA + I K+ Q Q
Sbjct: 735 KDDKGK----RKRKSSTSGS-----DFDTKKGKSAKSS----------IISKKKRQTQSE 775
Query: 248 SPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPK 307
S SE + + +S + A+ +T + PN KD++S+E K
Sbjct: 776 SSNYDSELEKEIKSMSKIG-------------AARTTKKRIPNTKDFDSSEDEKHSKKGM 822
Query: 308 DTELSQESDFKENGITEEKSKSEESKRMEPI-AIIITDTEISEFDVTKSKNVPKQFLISA 366
D + + + G +++ + +E + + DT I E +PK+ SA
Sbjct: 823 DNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL----RDRLPKKQQASA 878
Query: 367 ENEQV 371
+ V
Sbjct: 879 STDGV 883
Score = 31.6 bits (70), Expect = 1.4
Identities = 70/346 (20%), Positives = 136/346 (39%), Gaps = 35/346 (10%)
Query: 47 LKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQ 106
LK +AG + ++ +G+ + + A +S+ R+ +SESS LE E++
Sbjct: 729 LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIK 788
Query: 107 PAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSD--CSIKVQEEAEILDIQ 164
A +KK +IP K + HSK D+ ++K +E D +
Sbjct: 789 SMSKIGAARTTKK------RIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE 842
Query: 165 TQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
+ + + A+ T D I D + + ++++T G +S G + ++++
Sbjct: 843 RKQE-RETFSSAEGTVDKDTTIMEL-RDRLPKKQQASASTDGVDKLS---GKEQSFTSLE 897
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNST 284
+ ++ KEK + L+T Q LSD+ DQ +E S
Sbjct: 898 -----VRKVAETKEK-------SKHLKTKTCKKVQDGLSDIAEKFLKKDQS--DETSEDD 943
Query: 285 LESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE----SKRMEPIAI 340
+ + G + + + K K ++ Q+ + +G TE+ + EE K ++ I
Sbjct: 944 KKQSKKGTEEKKK---PSDFKKKVIKMEQQYESSSDG-TEKLPEREEICHFPKGIKQIKN 999
Query: 341 IITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSE 386
TD E + + K L + G + + ED+ S+
Sbjct: 1000 GTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1045
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 53.9 bits (128), Expect = 3e-07
Identities = 74/354 (20%), Positives = 146/354 (41%), Gaps = 57/354 (16%)
Query: 11 ENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASD 70
++ ++K+S G+ G E+ KR K K+ + + ++D + +E G +
Sbjct: 1075 DSSEDKKSKNGAYGREK----------KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNS 1124
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLS-----KKKAKSRL 125
+ LKR+ R +R+ SSK+ E+Q ++ DA+ S KKK ++
Sbjct: 1125 SDK-------RLKRIELRERRNLSSKRNTK---EIQSGSSSSDAEESSEDNKKKKQRTSS 1174
Query: 126 KIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEG 185
K + + KR++ + I ++I D Q + + ++ + + ++E
Sbjct: 1175 KKKAV-IVKEKKRNSLRTSTKRKQADITSSSSSDIED-DDQNSIGEGSSDEQKIKPVTEN 1232
Query: 186 ISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQ 245
+ C+S+ + + V + DN ++LEEI+ +
Sbjct: 1233 LVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSS 1292
Query: 246 QASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAP------------NGKD 293
P E + +Q ++ P Q+ E+ + + ES D
Sbjct: 1293 DDEPEEGKKRTGKQ---NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSD 1349
Query: 294 YESTEIVAEETKPKD-------------TELSQESDFKENGITEEKSKSEESKR 334
ES E ++TKPK+ +E S++SDF+E+G++EE S+SE+ +R
Sbjct: 1350 GESGE--EKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1401
Score = 36.2 bits (82), Expect = 0.058
Identities = 85/455 (18%), Positives = 161/455 (35%), Gaps = 59/455 (12%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRR-----------KKAAKALKPKAGS---EAADV 58
K E++ S G E+ E+ + F + +K +K ++ K E +D
Sbjct: 1004 KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1063
Query: 59 ARKCPQEAGASDQPEPTR---GAWASLKRLV-----TRRKRSESSKQQKPLEGEMQPAIN 110
A K + + D E + GA+ K+ + RKR + S + N
Sbjct: 1064 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1123
Query: 111 AEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLN 170
+ D L + + + R + + + + + S E+S K +++ +T +
Sbjct: 1124 SSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ------RTSSKKK 1177
Query: 171 DQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLIL 230
K K L RK D + S+ S+ + I + + ++
Sbjct: 1178 AVIVKEKKRNSLRTSTKRKQAD-ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1236
Query: 231 EEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPN 290
+ D ++ P+ + D D P I + ++EE +
Sbjct: 1237 SHTGFCQSSGDEALSKSVPVTVDDDD------DDNDPENRIAKKMLLEEIKANLSSDEDG 1290
Query: 291 GKDYESTEIVAE-----ETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDT 345
D E E E P D E + + + + +EE K R+ + ++D
Sbjct: 1291 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1350
Query: 346 EISEFDVTKSKNVPK-----QFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASS-- 398
E E TK K + + +S+E+ + F ++G + SE + T S+
Sbjct: 1351 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDF-QESGVSEEVSESEDEQRPRTRSAKK 1409
Query: 399 --LVKNAIQLSIEQ-------LVNEMASDDNKINN 424
L +N Q S +Q V E +S +NK N+
Sbjct: 1410 AELEEN--QRSYKQKKKRRRIKVQEDSSSENKSNS 1442
Score = 31.6 bits (70), Expect = 1.4
Identities = 62/305 (20%), Positives = 115/305 (37%), Gaps = 59/305 (19%)
Query: 88 RRKRSESSKQQKPLEGEMQPAINAEDADLSKK-KAKSRLKIPCIKFPR---------GPK 137
R R +++ ++P E P + D + ++ K K +L +P K + PK
Sbjct: 655 RSPRVKTTPLRRPTE--TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK 712
Query: 138 -----RSNHSKIIE---DSDCSIKVQEEAEILD--IQTQTPLNDQATKAKSTQDLSEGIS 187
+S S+ ++ DSD + + +E + + T +N+ T K+ DL
Sbjct: 713 PNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAG 772
Query: 188 RKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQA 247
+ D + S+TSG + G SA + I K+ Q Q
Sbjct: 773 KDDKGK----RKRKSSTSGS-----DFDTKKGKSAKSS----------IISKKKRQTQSE 813
Query: 248 SPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPK 307
S SE + + +S + A+ +T + PN KD++S+E K
Sbjct: 814 SSNYDSELEKEIKSMSKIG-------------AARTTKKRIPNTKDFDSSEDEKHSKKGM 860
Query: 308 DTELSQESDFKENGITEEKSKSEESKRMEPI-AIIITDTEISEFDVTKSKNVPKQFLISA 366
D + + + G +++ + +E + + DT I E +PK+ SA
Sbjct: 861 DNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL----RDRLPKKQQASA 916
Query: 367 ENEQV 371
+ V
Sbjct: 917 STDGV 921
Score = 31.6 bits (70), Expect = 1.4
Identities = 70/346 (20%), Positives = 136/346 (39%), Gaps = 35/346 (10%)
Query: 47 LKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQ 106
LK +AG + ++ +G+ + + A +S+ R+ +SESS LE E++
Sbjct: 767 LKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIK 826
Query: 107 PAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSD--CSIKVQEEAEILDIQ 164
A +KK +IP K + HSK D+ ++K +E D +
Sbjct: 827 SMSKIGAARTTKK------RIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE 880
Query: 165 TQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
+ + + A+ T D I D + + ++++T G +S G + ++++
Sbjct: 881 RKQE-RETFSSAEGTVDKDTTIMEL-RDRLPKKQQASASTDGVDKLS---GKEQSFTSLE 935
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNST 284
+ ++ KEK + L+T Q LSD+ DQ +E S
Sbjct: 936 -----VRKVAETKEK-------SKHLKTKTCKKVQDGLSDIAEKFLKKDQS--DETSEDD 981
Query: 285 LESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE----SKRMEPIAI 340
+ + G + + + K K ++ Q+ + +G TE+ + EE K ++ I
Sbjct: 982 KKQSKKGTEEKKK---PSDFKKKVIKMEQQYESSSDG-TEKLPEREEICHFPKGIKQIKN 1037
Query: 341 IITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSE 386
TD E + + K L + G + + ED+ S+
Sbjct: 1038 GTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1083
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/381 (19%), Positives = 141/381 (37%), Gaps = 59/381 (15%)
Query: 43 AAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLE 102
++K KPK + V K +E + E + +T +++K
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 103 GEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILD 162
E + AE+ +++ KK+ + P +K G K QEE E D
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG------------QEEEEEED 540
Query: 163 IQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSA 222
+ +DQA + S + EG S K+ E E E E ++
Sbjct: 541 ---EGAKSDQAEEGGSEK---EGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594
Query: 223 IQTGTLILEEIETIKEKQDVQPQQASPLE------TSETDHQQPVLSDVP---------- 266
+ T ++ + + K ++ P SP+E ++ ++ S VP
Sbjct: 595 VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 654
Query: 267 PLPAIP---------DQQIVEEASNSTLESAPNGKDYESTEIVAEETK----------PK 307
P+P P + VEE + S + +P + E+ E K PK
Sbjct: 655 PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 714
Query: 308 DTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTK-SKNVPKQFLISA 366
+ ++ ++ + ++ EK K+E + E +A ++T T+ + + K +K K
Sbjct: 715 EEKVEKKEEKPKD--VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 772
Query: 367 ENEQVGVFANDNGFEDRTSEQ 387
E E+ G + G E+ S++
Sbjct: 773 EKEKAG---GEGGSEEEGSDK 790
Score = 33.1 bits (74), Expect = 0.49
Identities = 85/408 (20%), Positives = 155/408 (37%), Gaps = 69/408 (16%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSE--AADVARKCPQEAGASD 70
K+E EG AE + E+A K KK + + A E AD + P++A +
Sbjct: 561 KEEGEQEEGETEAEAEGEEAEA---KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV 617
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGE------MQPAINAEDADLSKKKAKSR 124
P S ++ +S + P+E + P + +SK + +
Sbjct: 618 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 677
Query: 125 LKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSE 184
K P P+ P SK E K +EE E+ + + + + K K +
Sbjct: 678 AKSPV---PKSPVEEAKSKA-EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE--- 730
Query: 185 GISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQP 244
+K V E V+ T + SV++ L+ + G + +E KEK+
Sbjct: 731 --KKKAESPVKEEAVAEVVTITK---SVKVHLEK--ETKEEGKPLQQE----KEKEKAGG 779
Query: 245 QQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEET 304
+ S E S+ + A S E + E E V +ET
Sbjct: 780 EGGSEEEGSD-----------------------KGAKGSRKEDIAVNGEVEGKEEVEQET 816
Query: 305 KPKDTELSQESDFKENGI----TEEKSKSEESKRMEPIAIIITDTEI-SEFDVTKSKNVP 359
K K + +E NG+ +EK ++S+ E + + T +I SE +K +
Sbjct: 817 KEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE--EKVVVTKTVEKITSEGGDGATKYIT 874
Query: 360 KQFLISAENEQVGVFANDNGFEDR--TSEQYETLLIETASSLVKNAIQ 405
K ++ + E+ ++ FE++ ++++ E + T+ ++VK Q
Sbjct: 875 KSVTVTQKVEE-----HEETFEEKLVSTKKVEKV---TSHAIVKEVTQ 914
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 46.6 bits (109), Expect = 4e-05
Identities = 75/381 (19%), Positives = 141/381 (37%), Gaps = 59/381 (15%)
Query: 43 AAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLE 102
++K KPK + V K +E + E + +T +++K
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 103 GEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILD 162
E + AE+ +++ KK+ + P +K G K QEE E D
Sbjct: 117 EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG------------QEEEEEED 164
Query: 163 IQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSA 222
+ +DQA + S + EG S K+ E E E E ++
Sbjct: 165 ---EGAKSDQAEEGGSEK---EGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218
Query: 223 IQTGTLILEEIETIKEKQDVQPQQASPLE------TSETDHQQPVLSDVP---------- 266
+ T ++ + + K ++ P SP+E ++ ++ S VP
Sbjct: 219 VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 278
Query: 267 PLPAIP---------DQQIVEEASNSTLESAPNGKDYESTEIVAEETK----------PK 307
P+P P + VEE + S + +P + E+ E K PK
Sbjct: 279 PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 338
Query: 308 DTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTK-SKNVPKQFLISA 366
+ ++ ++ + ++ EK K+E + E +A ++T T+ + + K +K K
Sbjct: 339 EEKVEKKEEKPKD--VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 396
Query: 367 ENEQVGVFANDNGFEDRTSEQ 387
E E+ G + G E+ S++
Sbjct: 397 EKEKAG---GEGGSEEEGSDK 414
Score = 33.1 bits (74), Expect = 0.49
Identities = 85/408 (20%), Positives = 155/408 (37%), Gaps = 69/408 (16%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSE--AADVARKCPQEAGASD 70
K+E EG AE + E+A K KK + + A E AD + P++A +
Sbjct: 185 KEEGEQEEGETEAEAEGEEAEA---KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV 241
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGE------MQPAINAEDADLSKKKAKSR 124
P S ++ +S + P+E + P + +SK + +
Sbjct: 242 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 301
Query: 125 LKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSE 184
K P P+ P SK E K +EE E+ + + + + K K +
Sbjct: 302 AKSPV---PKSPVEEAKSKA-EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE--- 354
Query: 185 GISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQP 244
+K V E V+ T + SV++ L+ + G + +E KEK+
Sbjct: 355 --KKKAESPVKEEAVAEVVTITK---SVKVHLEK--ETKEEGKPLQQE----KEKEKAGG 403
Query: 245 QQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEET 304
+ S E S+ + A S E + E E V +ET
Sbjct: 404 EGGSEEEGSD-----------------------KGAKGSRKEDIAVNGEVEGKEEVEQET 440
Query: 305 KPKDTELSQESDFKENGI----TEEKSKSEESKRMEPIAIIITDTEI-SEFDVTKSKNVP 359
K K + +E NG+ +EK ++S+ E + + T +I SE +K +
Sbjct: 441 KEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE--EKVVVTKTVEKITSEGGDGATKYIT 498
Query: 360 KQFLISAENEQVGVFANDNGFEDR--TSEQYETLLIETASSLVKNAIQ 405
K ++ + E+ ++ FE++ ++++ E + T+ ++VK Q
Sbjct: 499 KSVTVTQKVEE-----HEETFEEKLVSTKKVEKV---TSHAIVKEVTQ 538
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 45.8 bits (107), Expect = 7e-05
Identities = 73/347 (21%), Positives = 136/347 (39%), Gaps = 41/347 (11%)
Query: 15 EKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPK-----AGSEAADVAR--KCPQEAG 67
+KR+ GS E KA ++ +A K + AGS+ D + P++AG
Sbjct: 689 KKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAG 748
Query: 68 ASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKI 127
+ + E W S KRLVT RK+S+S ++K + + D K +S + I
Sbjct: 749 SPTEGEGV-STWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSI 807
Query: 128 PCIKFPRG-----PKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDL 182
KF G P +ED+ + ++++ D+ PL++ + +
Sbjct: 808 K--KFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDS---DVPAVVPLSEYDAVEREKMEA 862
Query: 183 SEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDV 242
+ + E + + S +V + + +G A T+I E +
Sbjct: 863 QQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRA---ATIIEERSPSWISASVT 919
Query: 243 QP----QQASPLETSETDHQQPVLSDVP-----PLP---------AIPDQQIVEEASNST 284
+P + + L T E ++ + + P PLP + + ++ EA +
Sbjct: 920 EPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAA 979
Query: 285 LESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
+ P G + + AEET + +SQ +D + TEE + +E
Sbjct: 980 ETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDT--TEEATPVQE 1024
Score = 33.1 bits (74), Expect = 0.49
Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 23/140 (16%)
Query: 6 SEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQE 65
+++ ++ D + +G A +E + C ++ A+V + E
Sbjct: 548 TQVPADSPDSQEEQKGESSASSPEEPEEITCLEKG--------------LAEVQQDGEAE 593
Query: 66 AGASDQPEPTRGA---WASLKRLVTRRKR----SESSKQQKPLEGEMQPAINAEDADLSK 118
GA+ E R WAS K++VT +KR SES K+ + L+ +++ ++ S+
Sbjct: 594 EGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDE-LDKVKSATLSSTESTASE 652
Query: 119 KKAKSRLKIPCIKFPRGPKR 138
+ + + + K P PKR
Sbjct: 653 MQEEMKGSVEEPK-PEEPKR 671
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 45.8 bits (107), Expect = 7e-05
Identities = 73/347 (21%), Positives = 136/347 (39%), Gaps = 41/347 (11%)
Query: 15 EKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPK-----AGSEAADVAR--KCPQEAG 67
+KR+ GS E KA ++ +A K + AGS+ D + P++AG
Sbjct: 591 KKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAG 650
Query: 68 ASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKI 127
+ + E W S KRLVT RK+S+S ++K + + D K +S + I
Sbjct: 651 SPTEGEGV-STWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSI 709
Query: 128 PCIKFPRG-----PKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDL 182
KF G P +ED+ + ++++ D+ PL++ + +
Sbjct: 710 K--KFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDS---DVPAVVPLSEYDAVEREKMEA 764
Query: 183 SEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDV 242
+ + E + + S +V + + +G A T+I E +
Sbjct: 765 QQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRA---ATIIEERSPSWISASVT 821
Query: 243 QP----QQASPLETSETDHQQPVLSDVP-----PLP---------AIPDQQIVEEASNST 284
+P + + L T E ++ + + P PLP + + ++ EA +
Sbjct: 822 EPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAA 881
Query: 285 LESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
+ P G + + AEET + +SQ +D + TEE + +E
Sbjct: 882 ETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDT--TEEATPVQE 926
Score = 33.1 bits (74), Expect = 0.49
Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 23/140 (16%)
Query: 6 SEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQE 65
+++ ++ D + +G A +E + C ++ A+V + E
Sbjct: 450 TQVPADSPDSQEEQKGESSASSPEEPEEITCLEKG--------------LAEVQQDGEAE 495
Query: 66 AGASDQPEPTRGA---WASLKRLVTRRKR----SESSKQQKPLEGEMQPAINAEDADLSK 118
GA+ E R WAS K++VT +KR SES K+ + L+ +++ ++ S+
Sbjct: 496 EGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDE-LDKVKSATLSSTESTASE 554
Query: 119 KKAKSRLKIPCIKFPRGPKR 138
+ + + + K P PKR
Sbjct: 555 MQEEMKGSVEEPK-PEEPKR 573
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 45.4 bits (106), Expect = 1e-04
Identities = 73/357 (20%), Positives = 141/357 (39%), Gaps = 22/357 (6%)
Query: 17 RSAEGSPGAER---QKEKASM-LCFKRRKKAAKALKPKAGSEAA-DVARKCPQEAGASDQ 71
R SP E +K+KA + + +KK + +K K+ E A DV +K P +A + Q
Sbjct: 301 RPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQ 360
Query: 72 PEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIK 131
A A+ K+ K+ +S K +KP E E E + + AKS K +
Sbjct: 361 GTVKIAAQAAAKK---DEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVP 417
Query: 132 FPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDG 191
+ K E SIK + + T+T +Q + + + S + K+
Sbjct: 418 SDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTV--EQEIRKEKSGKTSSILKDKEP 475
Query: 192 DEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLE 251
+ E V S E + + ++ L+ + K + ++ + +
Sbjct: 476 IKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAIS 535
Query: 252 TSETDHQQPVLSDVPPLP-AIPDQQIVEEASNSTLESAPNGK--------DYESTEIVAE 302
H+Q ++ + P+++++++ T+E K + E I +
Sbjct: 536 EKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTD 595
Query: 303 ETK--PKDTELSQESDFKENGITEEKSKSE-ESKRMEPIAIIITDTEISEFDVTKSK 356
+ K PK T ES K+ I+E++SK + + K + + + +VTK++
Sbjct: 596 KPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAE 652
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 43.1 bits (100), Expect = 5e-04
Identities = 86/382 (22%), Positives = 152/382 (39%), Gaps = 39/382 (10%)
Query: 4 TISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAK-ALKPKAGSEAADVA-RK 61
++S I E K ++S SP QK+ A + FK++ A + G ++ V+ +K
Sbjct: 315 SVSNIATEIKKGQQSGTVSP----QKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQK 370
Query: 62 CPQEAGASDQPEPTRGAWASLK---RLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSK 118
P SD+ + +K + T + + + + E + I E D K
Sbjct: 371 QPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEK 430
Query: 119 KKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKS 178
S K P +K K S S+ + ++++ + + +Q P AT +
Sbjct: 431 SGTVSSQKQPALKATTDEKDSV-------SNIATEIKDGEKSGTVSSQKPPALTATSDEE 483
Query: 179 TQDLSEGISRKDGDEV----CESNVSNSTTSGEK--VISVELGLDNGHSAIQTGTLILEE 232
LS KDG++ ++ TS EK ++ G +G + + + ++
Sbjct: 484 GSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSS---QK 540
Query: 233 IETIKEKQDVQPQQAS-PLETSETDHQQPVLSDVPP-LPAIPDQQIVEEASNSTLESAPN 290
T+K D + E + + + V S+ PP L A D++ +S L A
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEK------DSVLNIARG 594
Query: 291 GKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKRME----PIAIIITDTE 346
K E T+ V+ KP S E D N IT EK E S+++ P +D E
Sbjct: 595 KKYGEKTKRVSSRKKPSLEATSDEKDSFSN-ITREKKDGEISRKVSSQKPPALKGTSDEE 653
Query: 347 ISEFDVTK-SKNVPKQFLISAE 367
S + + +K+ K +S+E
Sbjct: 654 DSVLGIARENKDGEKSRTVSSE 675
Score = 36.2 bits (82), Expect = 0.058
Identities = 73/341 (21%), Positives = 133/341 (39%), Gaps = 42/341 (12%)
Query: 53 SEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEG----EMQPA 108
S+AA + P S Q +P A + K V+ + ++ P+ G + QPA
Sbjct: 249 SKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN---IATEIKEGPISGTVSSQKQPA 305
Query: 109 INAEDADLSKKKAKSRLKIPCIKFPRG----PKRSNHSKIIEDSDCSI-----KVQEEAE 159
E A +K + S + K + P++ + K+I S+ ++ +
Sbjct: 306 ---EKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGK 362
Query: 160 ILDIQTQTPLNDQATKAKSTQDLSEGISRKDG------DEVCESNVSNSTTSGEKVISVE 213
+ +Q +AT K+ L+ KDG + + +T + V ++
Sbjct: 363 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422
Query: 214 LGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQAS-PLETSETDHQQPVLSDVPP-LPAI 271
+ +G ++GT+ ++ +K D + ++ E + + V S PP L A
Sbjct: 423 TEIKDGE---KSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTAT 479
Query: 272 PDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
D++ S L A KD E + V+ KP S E D N IT K E
Sbjct: 480 SDEE------GSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSN-ITRGKKDGEI 532
Query: 332 SKRME----PIAIIITDTEISEFDVTK-SKNVPKQFLISAE 367
S+++ P +D E S + + +K+ K +S+E
Sbjct: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSE 573
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 43.1 bits (100), Expect = 5e-04
Identities = 75/335 (22%), Positives = 128/335 (38%), Gaps = 38/335 (11%)
Query: 11 ENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASD 70
E K ++ SP + EKA + K A+A P+ K P EA +
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCI 130
+ E A + E+ +K E + A S +KAKS +K
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA-------KSPEKAKSPVKAEA- 674
Query: 131 KFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRK- 189
K P K ++ V+EEA+ + + ++P+ ++ AKS + + +
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE-KAKSPVKEE---AKSPEKAKSPVKEEA 730
Query: 190 DGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASP 249
E +S V S EK S E + TL ++++ + K + + SP
Sbjct: 731 KTPEKAKSPVKEEAKSPEKAKSPE----------KAKTL---DVKSPEAKTPAKEEARSP 777
Query: 250 LETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDT 309
+ + PV +V P + E+A E P ++ +S V EE KP++
Sbjct: 778 ADKFPEKAKSPVKEEVKS-PEKAKSPLKEDAKAPEKE-IPKKEEVKSP--VKEEEKPQEV 833
Query: 310 EL------SQESDFKENGITEEK--SKSEESKRME 336
++ ++E TEEK SK EE+ + E
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/333 (21%), Positives = 125/333 (37%), Gaps = 46/333 (13%)
Query: 13 KDEKRSAEG--SPGAERQK--EKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGA 68
K+E +S E SP E K EKA + K KA P + K P++A
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 69 SDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIP 128
D P A + K E +K P++ E++ S +KAKS LK
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKS--PVKEEVK----------SPEKAKSPLK-- 804
Query: 129 CIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKST-------QD 181
+ + P++ K E+ +K +E+ + + ++ + P + KA +T
Sbjct: 805 --EDAKAPEKEIPKK--EEVKSPVKEEEKPQEVKVK-EPPKKAEEEKAPATPKTEEKKDS 859
Query: 182 LSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQD 241
E +K+ + K VE + + T E ++ K+D
Sbjct: 860 KKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 242 VQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVA 301
+P++ + + E D + + P PA E+AP KD + +
Sbjct: 920 AKPKEKTEVAKKEPDDAK---AKEPSKPA------------EKKEAAPEKKDTKEEKAKK 964
Query: 302 EETKPKDTELSQESDFKENGITEEKSKSEESKR 334
E KPK TE + D K K K+E++++
Sbjct: 965 PEEKPK-TEAKAKEDDKTLSKEPSKPKAEKAEK 996
Score = 38.5 bits (88), Expect = 0.012
Identities = 62/355 (17%), Positives = 134/355 (37%), Gaps = 17/355 (4%)
Query: 11 ENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASD 70
E K ++ SP + EKA + K +A P+ + K P++A +
Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCI 130
+ E A A + K K++ E + + E ++ K+ + K P
Sbjct: 589 KEEAKSPAEAK-----SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643
Query: 131 KFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRK- 189
+ + P+++ S E++ K + + + + +AKS + + +
Sbjct: 644 EEAKSPEKAK-SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 190 DGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASP 249
E +S V S EK S + + + + + EE ++ ++ + P++A
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPV--KEEAKTPEKAKSPVKEEAKSPEKAK--SPEKAKT 758
Query: 250 LETSETDHQQPVLSDV-PPLPAIPDQ---QIVEEASNSTLESAPNGKDYESTEIVAEETK 305
L+ + + P + P P++ + EE + +P +D ++ E + +
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 306 PKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPK 360
+ + +E +E + E K+EE K P + + S+ + K PK
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEK--APATPKTEEKKDSKKEEAPKKEAPK 871
Score = 30.4 bits (67), Expect = 3.2
Identities = 53/263 (20%), Positives = 99/263 (37%), Gaps = 20/263 (7%)
Query: 86 VTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKII 145
VT E K+ K EG+ + E+A+ +++ KS P + P++ S +
Sbjct: 466 VTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKS----PPAEEAASPEKEAKSPVK 521
Query: 146 ED--SDCSIKVQEEAEILD-IQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNS 202
E+ S K E+ E + ++P ++ + + E S + + + V +
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 203 TTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKE-KQDVQPQQASPLETSETDHQQPV 261
+ S + + + EE ++ E K V+ + SP E + +
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 262 LSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTE-----IVAEETKPKDTELSQESD 316
+ P EEA + +P + +S E + AE P+ +S
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE----KAKSP 697
Query: 317 FKENGITEEKSKS---EESKRME 336
KE + EK+KS EE+K E
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPE 720
Score = 29.6 bits (65), Expect = 5.5
Identities = 17/80 (21%), Positives = 36/80 (45%)
Query: 260 PVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKE 319
P + V + ++ ++ S E+ + E T++ E T+ ++ E +E +E
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 320 NGITEEKSKSEESKRMEPIA 339
G EE+++ E + P A
Sbjct: 487 EGGEEEEAEGGEEETKSPPA 506
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 42.4 bits (98), Expect = 8e-04
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 41/258 (15%)
Query: 37 FKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSK 96
+ RR+ ++ L ++ S + +RK + S + + KR +R + S S
Sbjct: 327 YGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP 386
Query: 97 QQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFP----RG-----PKRSNHSKIIED 147
+ PL + A+LS+KK + K +G P++ N S +D
Sbjct: 387 VRLPLNSSL-------GAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 148 SDC-------SIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVS 200
S S+K+++ A ++ T LN T+ K++ D + ++ ++ ++
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLN---TEVKNSSDTGKVKLDENSEKHLVKDLK 496
Query: 201 NSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETI-KEKQDVQPQQASP---LETSETD 256
T K I A++ + +E ET KE P ASP L T+
Sbjct: 497 AQGTRDSKPI-----------ALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPP 545
Query: 257 HQQPVLSDVPPLPAIPDQ 274
Q P L +PP+PA+P Q
Sbjct: 546 PQTPPLPPLPPIPALPQQ 563
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 42.4 bits (98), Expect = 8e-04
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 41/258 (15%)
Query: 37 FKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSK 96
+ RR+ ++ L ++ S + +RK + S + + KR +R + S S
Sbjct: 327 YGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP 386
Query: 97 QQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFP----RG-----PKRSNHSKIIED 147
+ PL + A+LS+KK + K +G P++ N S +D
Sbjct: 387 VRLPLNSSL-------GAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 148 SDC-------SIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVS 200
S S+K+++ A ++ T LN T+ K++ D + ++ ++ ++
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLN---TEVKNSSDTGKVKLDENSEKHLVKDLK 496
Query: 201 NSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETI-KEKQDVQPQQASP---LETSETD 256
T K I A++ + +E ET KE P ASP L T+
Sbjct: 497 AQGTRDSKPI-----------ALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPP 545
Query: 257 HQQPVLSDVPPLPAIPDQ 274
Q P L +PP+PA+P Q
Sbjct: 546 PQTPPLPPLPPIPALPQQ 563
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 41.6 bits (96), Expect = 0.001
Identities = 82/380 (21%), Positives = 146/380 (38%), Gaps = 35/380 (9%)
Query: 4 TISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAK-ALKPKAGSEAADVA-RK 61
++S I E K ++S SP QK+ A + FK++ A + G ++ V+ +K
Sbjct: 315 SVSNIATEIKKGQQSGTVSP----QKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQK 370
Query: 62 CPQEAGASDQPEPTRGAWASLK---RLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSK 118
P SD+ + +K + T + + + + E + I E D K
Sbjct: 371 QPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEK 430
Query: 119 KKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKS 178
S K P +K K S S+ + ++++ + + +Q P AT +
Sbjct: 431 SGTVSSQKQPALKATTDEKDSV-------SNIATEIKDGEKSGTVSSQKPPALTATSDEE 483
Query: 179 TQDLSEGISRKDGDEV----CESNVSNSTTSGEK--VISVELGLDNGHSAIQTGTLILEE 232
LS KDG++ + TS EK ++ G +G + + + ++
Sbjct: 484 GSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSS---QK 540
Query: 233 IETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGK 292
T+K D + ++ + +S P P + +S L A K
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKP----PGLKASSAEKDSVLNIARGKK 596
Query: 293 DYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKRME----PIAIIITDTEIS 348
D E T+ V+ KP S E D N IT EK E S+++ P +D E S
Sbjct: 597 DGEKTKRVSSRKKPSLEATSDEKDSFSN-ITREKKDGEISRKVSSQKPPALKGTSDEEDS 655
Query: 349 EFDVTK-SKNVPKQFLISAE 367
+ + +K+ K +S+E
Sbjct: 656 VLGIARENKDGEKSRTVSSE 675
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 40.8 bits (94), Expect = 0.002
Identities = 91/414 (21%), Positives = 155/414 (37%), Gaps = 69/414 (16%)
Query: 4 TISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAK-ALKPKAGSEAADVA-RK 61
++S I E K+ ++S SP QK+ A + FK++ A + G ++ V+ +K
Sbjct: 109 SVSNIATEIKEGQQSGTVSP----QKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQK 164
Query: 62 CPQEAGASDQPEPTRGAWASLKRLV----TRRKRSESSKQQKPLEGEMQPAINAEDADLS 117
P ASD+ + +K + ++ ++ K EG + I E D
Sbjct: 165 QPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSN-IATEIKDGE 223
Query: 118 KKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAK 177
K S K P +K K S + E D I + +Q P +AT K
Sbjct: 224 KSGTVSSQKKPALKATSDEKDSFSNITREKKDGEIS-------RTVSSQKPPALKATSVK 276
Query: 178 STQDLSEGISRKDGDEVCESNVSN----STTSGEK--VISVELGLDNGHSAIQTGTLILE 231
L+ +KDG++ + T EK ++++ G NG + +
Sbjct: 277 EDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKP 336
Query: 232 EIETIKEKQD-----------------VQPQQASPL---------------ETSETDHQQ 259
++ +++D V Q+ L E + + +
Sbjct: 337 ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR 396
Query: 260 PVLSDVPP-LPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFK 318
V S+ PP L A D++ +S L A K E T+ V+ KP S E D
Sbjct: 397 TVSSEKPPGLKASSDEK------DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSF 450
Query: 319 ENGITEEKSKSEESKRME----PIAIIITDTEISEFDVTK-SKNVPKQFLISAE 367
N IT EK E S+++ P +D E S + + +K+ K +S+E
Sbjct: 451 SN-ITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSE 503
Score = 30.0 bits (66), Expect = 4.2
Identities = 87/370 (23%), Positives = 134/370 (36%), Gaps = 84/370 (22%)
Query: 2 ETTISEIHVENKDEKRSAEGS----PGAERQK-EKASMLCFKRRKKAAKALKPKAGSEAA 56
E ++ I E KD ++S S PG + + EK S+L R KK + + +
Sbjct: 277 EDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS----- 331
Query: 57 DVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQ---QKP--LEGEMQP---- 107
+RK P SD+ + S + +K E S++ QKP L+G
Sbjct: 332 --SRKKPALKATSDEKD-------SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSV 382
Query: 108 -AINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQ 166
I E+ D K + S K P +K SD E+ +L+I
Sbjct: 383 LGIARENKDGEKSRTVSSEKPPGLK--------------ASSD------EKDSVLNIARG 422
Query: 167 TPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGE---KVISVELGLDNGHSAI 223
++ + S + S + + D SN++ GE KV S + G S
Sbjct: 423 KKYGEKTKRVSSRKKPSLEATSDEKDSF--SNITREKKDGEISRKVSSQKPPALKGTSDE 480
Query: 224 QTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPP-LPAIPDQQIVEEASN 282
+ L + E + + + V S+ PP L A D++ +
Sbjct: 481 EDSVLGIAR------------------ENKDGEKSRTVSSEKPPGLKATSDEK------D 516
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESK----RMEPI 338
S L A KD E T V+ KP S E D I EK E+S+ + +P
Sbjct: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKD-SVLYIAREKKDGEKSRTVSSQKQPA 575
Query: 339 AIIITDTEIS 348
I D E S
Sbjct: 576 LKAICDKEDS 585
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2159
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2160 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2216
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2217 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2266
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2320
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2321 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2365
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2366 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2412
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2107 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2163
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2164 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2220
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2221 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2270
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2271 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2324
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2325 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2369
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2370 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2416
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2159
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2160 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2216
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2217 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2266
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2320
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2321 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2365
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2366 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2412
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2071 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2127
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2128 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2184
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2185 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2234
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2235 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2288
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2289 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2333
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2334 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2380
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2240 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2296
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2297 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2353
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2354 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2403
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2404 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2457
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2458 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2502
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2503 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2549
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2081 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2137
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2138 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2194
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2195 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2244
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2245 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2298
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2299 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2343
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2344 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2390
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2089 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2145
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2146 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2202
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2203 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2252
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2253 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2306
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2307 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2351
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2352 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2398
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.4 bits (93), Expect = 0.003
Identities = 73/349 (20%), Positives = 148/349 (42%), Gaps = 58/349 (16%)
Query: 2 ETTISEIHVENKDE-KRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E S VE + K+SAE A Q + A+ K RK+A + +A +E A + +
Sbjct: 2130 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE---KLRKEAEQEAARRAQAEQAALRQ 2186
Query: 61 KCPQEAGASDQPEPTRGAWASLKR-------LVTRRKRSESSKQQKPLEGEMQPAINAED 113
K +A ++ + + A +L++ L T R + E + QK L E + AE
Sbjct: 2187 K---QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEA 2243
Query: 114 ADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQ----TQTPL 169
+ ++++++ ++ ++ ++ E S +++ E L ++ TQ L
Sbjct: 2244 TEAARQRSQVEEELFSVRV----------QMEELSKLKARIEAENRALILRDKDNTQRFL 2293
Query: 170 NDQATKAKSTQDLSEGISRKDGD-----EVCESNVSNSTTSGEKVISVELGLDNGHSAIQ 224
++A K K + + +S + ++ E +++ EK++ ++ A+Q
Sbjct: 2294 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKM------QAVQ 2347
Query: 225 TGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEAS--N 282
T + E E +++++++ +QA L + D +Q QQ+ EE
Sbjct: 2348 EATRLKAEAELLQQQKELAQEQARRL---QEDKEQMA------------QQLAEETQGFQ 2392
Query: 283 STLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEE 331
TLE+ + S E AE K + E+S+ E + ++EE
Sbjct: 2393 RTLEAERQRQLEMSAE--AERLKLRVAEMSRAQARAEEDAQRFRKQAEE 2439
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 39.7 bits (91), Expect = 0.005
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 10/161 (6%)
Query: 9 HVENKDEKRSAEGSPGAERQK-EKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAG 67
+ + K ++ +PG + + +K S R+K A++ + ++ V +K P++A
Sbjct: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQS---DSTTQRRTVGKKQPKKAE 571
Query: 68 ASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKI 127
+ EP G + V SS+ + +G +P I E + A+ +
Sbjct: 572 KAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKK--- 628
Query: 128 PCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTP 168
K+ K S S+ I ++D S +E+E L +QTP
Sbjct: 629 ---KYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTP 666
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 38.5 bits (88), Expect = 0.012
Identities = 53/269 (19%), Positives = 104/269 (38%), Gaps = 28/269 (10%)
Query: 73 EPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKF 132
E TR + K L+ K++ KQ+K +E + + ++ + + K
Sbjct: 132 EVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEK------ 185
Query: 133 PRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGD 192
P + H K+ E+ + K Q+E E+ + +D T+ + DGD
Sbjct: 186 PEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGD 245
Query: 193 EVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLET 252
+ + SG+ D +AI+ ++ + D+ P ++P T
Sbjct: 246 GALSEAEAQALLSGDTQTDATSFYDRVWAAIR------DKYRSEALPTDL-PAPSAPDLT 298
Query: 253 SETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKP------ 306
+ Q PP+P+ P ++ EE E A ++ E +E+ E+ KP
Sbjct: 299 EPKEEQ-------PPVPSSPTEE-EEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE 350
Query: 307 -KDTELSQESDFKENGITEEKSKSEESKR 334
K +++ + E ++K EE++R
Sbjct: 351 DKMPPYDEQTQAFIDAAQEARNKFEEAER 379
>gi|5729734 activator of S phase kinase [Homo sapiens]
Length = 674
Score = 38.5 bits (88), Expect = 0.012
Identities = 52/225 (23%), Positives = 93/225 (41%), Gaps = 13/225 (5%)
Query: 130 IKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEG-ISR 188
I P R + K+ + CS+ E +I TQ PL+ K + D+SE +S
Sbjct: 416 IPHPSNELRGLNEKM--SNKCSMLSTAEDDIRQNFTQLPLHKN--KQECILDISEHTLSE 471
Query: 189 KDGDEVCESNVSNSTTSGEKVISVELGLDN-GHSAIQTGTLILEEIETIKEKQDVQP--Q 245
D +E+ + + + V + DN G Q +L + +KEK D+
Sbjct: 472 NDLEELRVDHYKCNIQASVHVS--DFSTDNSGSQPKQKSDTVLFPAKDLKEK-DLHSIFT 528
Query: 246 QASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETK 305
S L T + + + P P++ E ++S P+GK + +I+ +
Sbjct: 529 HDSGLITINSSQEHLTVQAKAPFHTPPEEP--NECDFKNMDSLPSGKIHRKVKIILGRNR 586
Query: 306 PKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEF 350
++ E + E D + IT+E+++ S + + T E SEF
Sbjct: 587 KENLEPNAEFDKRTEFITQEENRICSSPVQSLLDLFQTSEEKSEF 631
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 38.5 bits (88), Expect = 0.012
Identities = 45/216 (20%), Positives = 87/216 (40%), Gaps = 24/216 (11%)
Query: 2 ETTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARK 61
ETT+ + + E+ +E + +EK S L +++K K KP++G +A
Sbjct: 121 ETTVGSQEMTGRKEETKSE----PKEAEEKESTLASEKQKAEEKEAKPESGQKA------ 170
Query: 62 CPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKA 121
+A D+PEP A+++ + E + Q+K E +P A D + +
Sbjct: 171 ---DANDRDKPEPK----ATVEEEDAKTASQEETGQRK--ECSTEPKEKATDEEAKAESQ 221
Query: 122 KSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQD 181
K+ ++ P+ P +K + K +E + + + +P +Q + +
Sbjct: 222 KAVVEDEAKAEPKEPDGKEEAKHGAKEEADAK-EEAEDAEEAEPGSPSEEQEQDVEKEPE 280
Query: 182 LSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLD 217
G+ +E ES T G + + LG D
Sbjct: 281 GGAGVIPSSPEEWPES----PTGEGHNLSTDGLGPD 312
Score = 30.8 bits (68), Expect = 2.5
Identities = 35/159 (22%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 2 ETTISEIHVENKDEKRSAEGSPGAER-QKEKASMLCFKRRKKAAKALKPKAGSEAADVAR 60
E+ + + E K E + +G A+ KE+A K + A+ +P + SE +
Sbjct: 219 ESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADA---KEEAEDAEEAEPGSPSEEQEQDV 275
Query: 61 KCPQEAGAS-------DQPEPTRGAWASLKR------LVTRRKRSESSKQQKPLEGEMQP 107
+ E GA + PE G +L V + S S+ + P + P
Sbjct: 276 EKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSP 335
Query: 108 AINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIE 146
+ + +K + R+ P PRGP+ N I++
Sbjct: 336 PESPSSGEKKEKAPERRVSAPAR--PRGPRAQNRKAIVD 372
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 38.1 bits (87), Expect = 0.015
Identities = 89/424 (20%), Positives = 160/424 (37%), Gaps = 64/424 (15%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQP 72
K+ K+ + P E +KE K KK K K E +K P++A S P
Sbjct: 686 KEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTP 745
Query: 73 EPTRGAWASLKRLVTRRKRS---ESSKQQKPLE-GEMQ------PAINAEDADLSKKKAK 122
A+LK V +++ S +S KP E G+++ A A A +
Sbjct: 746 LSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATT 805
Query: 123 SRLKIPCIKFPRGPKR---------SNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQA 173
+ + GP + S+ + +D + +K +E DI+ Q L +
Sbjct: 806 AAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFE-ELKAEEVDVTKDIKPQLELIEDE 864
Query: 174 TKAKSTQDL-------------------SEGISRKDGDEVCESNVSNSTTSGEKVISVE- 213
K K T+ + EGI+ +G+ CE + E++ VE
Sbjct: 865 EKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQ-------TPEELEPVEK 917
Query: 214 LGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPD 273
G+D+ G E ET ++ + ++A E E D ++ V D
Sbjct: 918 QGVDDIEKFEDEGAGFEESSETGDYEEKAETEEA---EEPEEDGEEHVCVSASKHSPTED 974
Query: 274 QQIVEEASNSTL----ESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKS 329
++ + +++ + ES +G D AEE + E + +E E+K++
Sbjct: 975 EESAKAEADAYIREKRESVASGDDR------AEEDMDEAIEKGEAEQSEEEADEEDKAED 1028
Query: 330 EESKRMEPIAIIITDTEISEFD-VTKSKNVPKQF-LISAENEQVGVFANDNGFEDRTSEQ 387
+ EP + D ++ D ++ +Q+ ++ +Q+G A G E +S
Sbjct: 1029 AREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLG--AQSPGREPASSIH 1086
Query: 388 YETL 391
ETL
Sbjct: 1087 DETL 1090
Score = 34.3 bits (77), Expect = 0.22
Identities = 72/380 (18%), Positives = 140/380 (36%), Gaps = 74/380 (19%)
Query: 13 KDEKRSAEGSPGAERQ----KEKASMLCFKRRKKAAKALKPKAGSE-AADVARKCPQEAG 67
KD+ E P + KE+ S + + +K A +KPKA E K E
Sbjct: 590 KDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDK 649
Query: 68 ASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKI 127
++ +P K + + ++ K++KP + E++ + E KK+ K +K
Sbjct: 650 KEEKEKPK-------KEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVK- 701
Query: 128 PCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDI--------QTQTPLN--------- 170
P + ++ ++ +K +E+ +I ++ TPL+
Sbjct: 702 -----KETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALK 756
Query: 171 ------------DQATKAKSTQDLSEGISRKDG---DEVCESNVSNSTT------SGEKV 209
D K + + +K+G + V + + +TT +G
Sbjct: 757 PKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAA 816
Query: 210 ISVELGLDNGHSAIQTGTLILEEIETIKEKQ-----DVQPQQASPLETSETDHQQPVLS- 263
I L+ S + + + ++ E +K ++ D++PQ + + +PV +
Sbjct: 817 IGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAY 876
Query: 264 ------DVPPLPA-IPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKD-----TEL 311
+V PA PD+ I E P + + V + K +D E
Sbjct: 877 VIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEES 936
Query: 312 SQESDFKENGITEEKSKSEE 331
S+ D++E TEE + EE
Sbjct: 937 SETGDYEEKAETEEAEEPEE 956
Score = 31.2 bits (69), Expect = 1.9
Identities = 91/434 (20%), Positives = 157/434 (36%), Gaps = 70/434 (16%)
Query: 13 KDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGS---EAADVARKCPQEAGAS 69
K E+ + S A + KEK + K+ KAA+A+ G+ AA +A G +
Sbjct: 761 KKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPA 820
Query: 70 DQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPC 129
+ E R +S + L + E ++ + +++P + + D K K ++
Sbjct: 821 KELEAERSLMSSPEDLT--KDFEELKAEEVDVTKDIKPQLELIE-DEEKLKETEPVEAYV 877
Query: 130 IKFPR----GPKRSNHSKIIE---DSDCSIKVQE---------------EAEILDIQTQT 167
I+ R GP S I + +C +E E E + +
Sbjct: 878 IQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESS 937
Query: 168 PLNDQATKAKSTQDLSEGISRKDGDE-VCESNVSNSTTSGE-------------KVISVE 213
D KA+ T++ E +DG+E VC S +S T E K SV
Sbjct: 938 ETGDYEEKAE-TEEAEE--PEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVA 994
Query: 214 LGLDNGHS----AIQTGTLILEEIETIKEK--QDVQPQQASPLETSETDHQQPVLSDVPP 267
G D AI+ G E E +E +D + ++ P + D+ V+
Sbjct: 995 SGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAE 1054
Query: 268 LPAIPDQQIV---------------EEASNSTLESAPNGKDYESTEIVAEETKPKDTELS 312
+Q E AS+ E+ P G + E+T E + + E +
Sbjct: 1055 AGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFT 1114
Query: 313 QESDFKEN--GITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPK--QFLISAEN 368
S + ++ I+ E + +E + T+ E +E + N+ K L S E
Sbjct: 1115 ATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEY 1174
Query: 369 EQVGVFANDNGFED 382
+ NGF +
Sbjct: 1175 SKPADVTPLNGFSE 1188
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 37.7 bits (86), Expect = 0.020
Identities = 73/361 (20%), Positives = 147/361 (40%), Gaps = 35/361 (9%)
Query: 11 ENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASD 70
E + E+R E ER+KEK +R ++ K + + ++A K + G
Sbjct: 568 ERERERREKEREREREREKEK------EREREKQKLKESEKERDSAKDKEKGKHDDGRKK 621
Query: 71 QPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDAD-----LSKKKAKSRL 125
+ E +K+L K+++ S+++ L +M + E D ++KK+K+ L
Sbjct: 622 EAE-------IIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAEL 674
Query: 126 KIPCIKF-PRGPKRSNHSKIIEDSDCSIKVQE-EAEILDIQTQTPLNDQATKAKSTQDLS 183
+ + K +K + D D K++ E +I +Q + + Q +A ++
Sbjct: 675 EDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDV 734
Query: 184 EGISRKDGDEV---CESNVSNSTTSGEKVISVELGLDNGHSAI-QTGTLILEEIETIKEK 239
G + +D E + + K++S + + H + + + +++ T+K +
Sbjct: 735 TGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQ 794
Query: 240 QDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEI 299
D Q Q LE E Q + + L Q +E +E+A D ++ ++
Sbjct: 795 VDAQLQVVRKLEEKEHLLQSNIGTGEKELGL--RTQALEMNKRKAMEAAQLADDLKA-QL 851
Query: 300 VAEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVP 359
+ K D + + EN +T+EK + E I+ + E ++ K NVP
Sbjct: 852 ELAQKKLHDF----QDEIVENSVTKEKDMFNFKRAQEDISRLRRKLETTK----KPDNVP 903
Query: 360 K 360
K
Sbjct: 904 K 904
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 37.4 bits (85), Expect = 0.026
Identities = 76/417 (18%), Positives = 164/417 (39%), Gaps = 37/417 (8%)
Query: 26 ERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRL 85
ER++E M ++ +K +K K G +++RK + + E ++ K+
Sbjct: 418 EREEEMKQMEVYRSH---SKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQH 474
Query: 86 VTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKII 145
+ K S ++K+Q+ +Q ++A L +K+ K I+ K + +I
Sbjct: 475 IEVLKESLTAKEQR--AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 532
Query: 146 EDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTS 205
+ D + + +L + + K K L E + D +N + T+
Sbjct: 533 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD---TTNTDTALTT 589
Query: 206 GEKVIS--------VELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDH 257
E+ ++ ++ D Q EEI+ K+ ++ S L+ ++
Sbjct: 590 LEEALAEKERTIERLKEQRDRDEREKQ------EEIDNYKKDLKDLKEKVSLLQGDLSEK 643
Query: 258 QQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDT-------- 309
+ +L ++ + +++ TLE A K E ++ ++ K +
Sbjct: 644 EASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASP 703
Query: 310 ELSQESDFKENGITEEKSKSEESK-RMEPIAIIITDTEISEFDVTKSKNVPKQFLISAEN 368
E+S E IT K +S +++ ++ + I+ + E + D K K + + +N
Sbjct: 704 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK-KIAELERQVKDQN 762
Query: 369 EQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNKINNL 425
++V + E + S Q ++E A N + S +QL + + D++I L
Sbjct: 763 KKVANLKHKEQVEKKKSAQ----MLEEARRREDN-LNDSSQQLQDSLRKKDDRIEEL 814
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 37.4 bits (85), Expect = 0.026
Identities = 79/374 (21%), Positives = 141/374 (37%), Gaps = 57/374 (15%)
Query: 4 TISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAK-ALKPKAGSEAADVA-RK 61
++S I E K+ ++S SP QK+ A + FK++ A + G ++ V+ +K
Sbjct: 59 SVSNIATEIKEGQQSGTVSP----QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQK 114
Query: 62 CPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAE-DADLSKKK 120
P SD+ + +K Q + + QPA+ A D + S
Sbjct: 115 QPASKATSDKTDSALNIATEIK----------DGLQCGTVSSQKQPALKATTDEEDSVSN 164
Query: 121 AKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQ 180
+ +K ++S + EE +L+I T+ +++ S +
Sbjct: 165 IATEIK--------DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQK 216
Query: 181 DLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQ 240
+ + + D V S ++ GEK +GT+ + +K
Sbjct: 217 QPALKATTDEEDSV--SIIATEIKDGEK----------------SGTVSSRKKPALKATS 258
Query: 241 DVQPQQAS-PLETSETDHQQPVLSDVPP-LPAIPDQQIVEEASNSTLESAPNGKDYESTE 298
D + ++ E + + + V S+ P L A D++ +S L A +D E T
Sbjct: 259 DEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEE------DSVLNIARGKEDGEKTR 312
Query: 299 IVAEETKPKDTELSQESDFKENGITEEKSKSEESKRME----PIAIIITDTEISEFDVTK 354
V+ KP S E D N IT EK E S+ + P +D E S + +
Sbjct: 313 RVSSRKKPALKATSDEKDSFSN-ITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAR 371
Query: 355 -SKNVPKQFLISAE 367
K+ K +S+E
Sbjct: 372 EEKDGEKSRTVSSE 385
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,192,092
Number of Sequences: 37866
Number of extensions: 679934
Number of successful extensions: 3002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 2740
Number of HSP's gapped (non-prelim): 483
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.