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Search of human proteins with 157671915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157671915 guanylate binding protein family, member 6 [Homo
sapiens]
(633 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157671915 guanylate binding protein family, member 6 [Homo sa... 1263 0.0
gi|31377634 guanylate binding protein 4 [Homo sapiens] 877 0.0
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 868 0.0
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 628 e-180
gi|166706903 guanylate binding protein 1, interferon-inducible, ... 627 e-180
gi|112382372 guanylate binding protein 3 [Homo sapiens] 615 e-176
gi|197333737 guanylate-binding protein 5 [Homo sapiens] 587 e-167
gi|16418425 guanylate-binding protein 5 [Homo sapiens] 587 e-167
gi|169160863 PREDICTED: similar to guanylate-binding protein 5 [... 109 7e-24
gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] 74 4e-13
gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] 74 4e-13
gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] 74 4e-13
gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] 67 7e-11
gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] 67 7e-11
gi|45827806 atlastin 3 [Homo sapiens] 66 1e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 1e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 1e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 52 1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 52 1e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 52 1e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 52 1e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 52 1e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 52 1e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 52 1e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 52 1e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 52 1e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 52 2e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 52 2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 4e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 51 4e-06
>gi|157671915 guanylate binding protein family, member 6 [Homo
sapiens]
Length = 633
Score = 1263 bits (3269), Expect = 0.0
Identities = 633/633 (100%), Positives = 633/633 (100%)
Query: 1 MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG 60
MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG
Sbjct: 1 MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG 60
Query: 61 QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV 120
QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV
Sbjct: 61 QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV 120
Query: 121 LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTV 180
LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTV
Sbjct: 121 LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTV 180
Query: 181 RDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPT 240
RDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPT
Sbjct: 181 RDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPT 240
Query: 241 NDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYV 300
NDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYV
Sbjct: 241 NDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYV 300
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE
Sbjct: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
Query: 361 REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES 420
REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES
Sbjct: 361 REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES 420
Query: 421 ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKA 480
ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKA
Sbjct: 421 ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKA 480
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH
Sbjct: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
Query: 541 LLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNL 600
LLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNL
Sbjct: 541 LLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNL 600
Query: 601 ADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF 633
ADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF
Sbjct: 601 ADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF 633
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 877 bits (2266), Expect = 0.0
Identities = 440/623 (70%), Positives = 520/623 (83%), Gaps = 1/623 (0%)
Query: 2 ESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQ 61
ES M+AP+CLVEN EQL VN +A++IL+KISQPVVVVAIVGLYRTGKSYLMN LAG+
Sbjct: 17 ESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGK 76
Query: 62 NHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVL 121
+GFPLGSTVQSETKGIWMWCVPH SKPNHTLVLLDTEGLGDVEK +PKNDSWIFALAVL
Sbjct: 77 RNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVL 136
Query: 122 LCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVR 181
L S+FVYNS+STINHQALEQLHYVTEL ELI+AKS PRPD EDS+EF SFFPDF+WTVR
Sbjct: 137 LSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVR 196
Query: 182 DFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTN 241
DFTLELKL+G+PITEDEYLENALKLI G NP++Q SN PRECIR FF KRKCFVFDRPTN
Sbjct: 197 DFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTN 256
Query: 242 DKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVE 301
DK L ++++V E+ L+ F Q++ FCSYIFTHA+TKTLREGI VTG RLGTL VTYV+
Sbjct: 257 DKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVD 316
Query: 302 AINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACER 361
AINSGAVPCLENAV LAQ EN AAVQRAAD+YSQQMAQ+++LPTDTLQELLD+HAACER
Sbjct: 317 AINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACER 376
Query: 362 EAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESI 421
EAIA+FMEHSFKDEN EFQKK ++T KKGDF+LQNEE+S +YCQA+L LS+ L ESI
Sbjct: 377 EAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESI 436
Query: 422 SAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKAL 481
G FSVPGGH LY+E K+++E DY VPRKGVKA EV Q FL+SQ+V+EESILQSDKAL
Sbjct: 437 LRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKAL 496
Query: 482 TDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHL 541
T EKA+A +RA KEAAEKEQELL++K +EQQQ MEAQ++S +E +AQ+++KL+ ERE+L
Sbjct: 497 TAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENL 556
Query: 542 LREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLA 601
LRE +L+H KVQ + L E F+KK E++N EI+Q K I++TKN+ + + LD +
Sbjct: 557 LREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLR-LLKILDMAS 615
Query: 602 DELTAILSAPAKLIGHGVKGVSS 624
+ + L +KL+G G K + S
Sbjct: 616 NIMIVTLPGASKLLGVGTKYLGS 638
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 868 bits (2244), Expect = 0.0
Identities = 437/632 (69%), Positives = 515/632 (81%)
Query: 1 MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG 60
M S M PVCL EN L+VN +A++IL I+QPVVVVAIVGLYRTGKSYLMN LAG
Sbjct: 1 MASEIHMPGPVCLTENTKGHLVVNSEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV 120
+N GFPLG TV+SETKGIWMWCVPHPSKPNHTL+LLDTEGLGD+EK DPK+DSWIFALAV
Sbjct: 61 KNKGFPLGCTVKSETKGIWMWCVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAV 120
Query: 121 LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTV 180
LL S+FVYNSM TINHQALEQLHYVTELTELI+AKS PRPD VEDS+EFVSFFPDF+WTV
Sbjct: 121 LLSSSFVYNSMGTINHQALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTV 180
Query: 181 RDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPT 240
RDFTLELKL+GHPITEDEYLENALKLI G NP++Q SN PRE IR FFPK+KCFVFDRP
Sbjct: 181 RDFTLELKLDGHPITEDEYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPI 240
Query: 241 NDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYV 300
NDK LL ++E+V E QLD FQ Q+ FCSYIFTHA+TKTLREGI VTGNRLG L TY+
Sbjct: 241 NDKKLLLHVEEVREDQLDSNFQMQSENFCSYIFTHAKTKTLREGILVTGNRLGMLVETYL 300
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
+AINSGA PCLENA+ LAQ ENSAAVQRAA++YSQQMAQ+V+ PTDTLQELLD+HA CE
Sbjct: 301 DAINSGATPCLENAMAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAVCE 360
Query: 361 REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES 420
REAIA+FME+SFKD++QEFQKK ++T KK DF+LQNEE+S +YCQA+L LS+ L ES
Sbjct: 361 REAIAVFMEYSFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKYCQAELKRLSELLTES 420
Query: 421 ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKA 480
IS G+F VPGGH +Y+E K++IEQDY VPRKGVKA EV Q FL+SQ+VIEESILQSDKA
Sbjct: 421 ISRGTFFVPGGHNIYLEAKKKIEQDYTLVPRKGVKADEVLQSFLQSQVVIEESILQSDKA 480
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT EKA+A +AKKEAAEKEQELL+QK +EQQQ MEAQ++S +ENIAQLK+K++ ERE+
Sbjct: 481 LTAGEKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMEREREN 540
Query: 541 LLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNL 600
+RE ML H KV + L EGFK+ +E +N EI++ K I+ +N++ ++ LD
Sbjct: 541 YMRELRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQIEAAENEEPSVFSQILDVA 600
Query: 601 ADELTAILSAPAKLIGHGVKGVSSLFKKHKLP 632
A L AKL+ G+K +SSL + + P
Sbjct: 601 GSIFIAALPGAAKLVDLGMKILSSLCNRLRNP 632
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 628 bits (1619), Expect = e-180
Identities = 308/566 (54%), Positives = 427/566 (75%), Gaps = 1/566 (0%)
Query: 10 PVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGS 69
P+ L++N QL+VN +A++IL I+QPVVVVAIVGLYRTGKSYLMN LAG+ +GF LGS
Sbjct: 10 PMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKNGFSLGS 69
Query: 70 TVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYN 129
TV+S TKGIWMWCVPHP KP HTLVLLDTEGLGD+EKGD +NDSWIFALA+LL STFVYN
Sbjct: 70 TVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYN 129
Query: 130 SMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKL 189
SM TIN QA++QLHYVTELT+ IKA SSP + V+DS +FVSFFP F+WT+RDFTLEL++
Sbjct: 130 SMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEV 189
Query: 190 NGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANI 249
+G PIT D+YLE +LKL +G + + ++ N PR CIR+FFPKRKCFVFD P K LA++
Sbjct: 190 DGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPA-PKKYLAHL 248
Query: 250 EKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVP 309
E++ E++L+P F EQ FCSYI +H+ KTL GI V G RL +L +TYV AI+SG +P
Sbjct: 249 EQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLP 308
Query: 310 CLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFME 369
C+ENAV+ LAQ ENSAAV++A +Y QQM Q+V+LPT+TLQELLD+H EREAI +FM+
Sbjct: 309 CMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMK 368
Query: 370 HSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVP 429
+SFKD +Q FQ+K ++ DF QN ++S C A L ++ L E + G+FS P
Sbjct: 369 NSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKP 428
Query: 430 GGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVA 489
GG++L+ + + ++ Y+QVPRKG++AKEV +++LES+ + +++LQ+D++L+++EKA+
Sbjct: 429 GGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIE 488
Query: 490 VDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMML 549
V+R K E+AE +++L++ ++ ++ ME ++KS +E++ QL EK++ +R L+ EQ L
Sbjct: 489 VERIKAESAEAAKKMLEEIQKKNEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTL 548
Query: 550 EHTQKVQNDWLHEGFKKKYEEMNAEI 575
+ Q L EGF+ + + + +I
Sbjct: 549 ALKLQEQERLLKEGFENESKRLQKDI 574
>gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
Length = 592
Score = 627 bits (1618), Expect = e-180
Identities = 311/581 (53%), Positives = 429/581 (73%), Gaps = 3/581 (0%)
Query: 1 MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG 60
M S M P+CL+EN N +L+ N +A++IL I+QP+VVVAIVGLYRTGKSYLMN LAG
Sbjct: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV 120
+ GF LGSTVQS TKGIWMWCVPHP KP H LVLLDTEGLGDVEKGD +NDSWIFALAV
Sbjct: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
Query: 121 LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSP--RPDGVEDSTEFVSFFPDFLW 178
LL STFVYNS+ TIN QA++QL+YVTELT I++KSSP + VEDS +FVSFFPDF+W
Sbjct: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
Query: 179 TVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDR 238
T+RDF+L+L+ +G P+T DEYL +LKL +G + + +T N PR CIR+FFPK+KCFVFDR
Sbjct: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
Query: 239 PTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVT 298
P + + L A +EK+ +++LDP+F +Q FCSYIF++++TKTL GI V G RL +L +T
Sbjct: 241 PVHRRKL-AQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLT 299
Query: 299 YVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAA 358
YV AI+SG +PC+ENAV+ LAQ ENSAAVQ+A +Y QQM Q+V+LPT+TLQELLD+H
Sbjct: 300 YVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRD 359
Query: 359 CEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLM 418
EREAI +F+ SFKD + FQK+ K+ DF QN+E+S C A L + L
Sbjct: 360 SEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLE 419
Query: 419 ESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSD 478
E + AG +S PGG++L+++ + +++ Y++ PRKG++A+E+ Q +L+S+ + ++ILQ+D
Sbjct: 420 EEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTD 479
Query: 479 KALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMER 538
+ LT++EK + V+R K E+A+ ++L++ ++ +Q ME +++S +E++ QL EK++ +R
Sbjct: 480 QTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDR 539
Query: 539 EHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
LL+EQ L + Q L EGF+K+ M EI +
Sbjct: 540 VQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
>gi|112382372 guanylate binding protein 3 [Homo sapiens]
Length = 595
Score = 615 bits (1585), Expect = e-176
Identities = 303/576 (52%), Positives = 421/576 (73%), Gaps = 1/576 (0%)
Query: 7 MLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFP 66
M P+CL+EN N +L+ N +A++IL I+QPVVVVAIVGLYRTGKSYLMN LAG+N GF
Sbjct: 7 MTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFS 66
Query: 67 LGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTF 126
LGSTV+S TKGIWMWCVPHP KP HTLVLLDTEGLGDV+KGD +NDSWIF LAVLL ST
Sbjct: 67 LGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTL 126
Query: 127 VYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLE 186
VYNSM TIN QA++QL+YVTELT I++KSSP + EDS +FVSFFPDF+WT+RDF+L+
Sbjct: 127 VYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLD 186
Query: 187 LKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLL 246
L+ +G P+T DEYLE +LKL QG + + + N PR CIR+FFPK+KCFVFD P + + L
Sbjct: 187 LEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRK-L 245
Query: 247 ANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSG 306
A +EK+ +++LDP+F +Q FCSYIF++++TKTL GI V G RL +L +TY+ AI+ G
Sbjct: 246 AQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRG 305
Query: 307 AVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAI 366
+PC+ENAV+ LAQ ENSAAVQ+A +Y QQM Q+V+LP +TLQELLD+H EREA +
Sbjct: 306 DLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEV 365
Query: 367 FMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSF 426
+M++SFKD + FQKK K+ DF QN+E+S C A L + L E + AG +
Sbjct: 366 YMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIY 425
Query: 427 SVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREK 486
S PGG+ L+++ + +E+ Y++ PRKG++A+E+ Q +L+S+ + ++ILQ+D+ LT++EK
Sbjct: 426 SKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQILTEKEK 485
Query: 487 AVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQI 546
+ V+ K E+A+ +++++ + QQ ME ++KS +E++ QL EK++ ER LL EQ
Sbjct: 486 EIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQLLEEQE 545
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMI 582
L + Q L E + + ++ EI + ++ +
Sbjct: 546 KTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTL 581
>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 587 bits (1513), Expect = e-167
Identities = 298/583 (51%), Positives = 413/583 (70%), Gaps = 8/583 (1%)
Query: 7 MLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFP 66
M P+CL+EN NEQL VNQ+A++IL I+QPVVVVAIVGLYRTGKSYLMN LAG+N GF
Sbjct: 7 MSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFS 66
Query: 67 LGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTF 126
+ STVQS TKGIW+WCVPHP+ PNHTLVLLDTEGLGDVEK D KND IFALA+LL STF
Sbjct: 67 VASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTF 126
Query: 127 VYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLE 186
VYN+++ I+ A++ LH VTELT+L+KA++SP D VED + SFFPD +WT+RDF L
Sbjct: 127 VYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLG 186
Query: 187 LKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLL 246
L+++G +T DEYLEN+L+ QG++ RVQ N PR CI++FFPK+KCF+FD P + K L
Sbjct: 187 LEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKK-L 245
Query: 247 ANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSG 306
A +E + + +L+P+F +Q FCSYIF+H+ TKTL GI V G+RL L +TYV AI+SG
Sbjct: 246 AQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTYVNAISSG 305
Query: 307 AVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAI 366
+PC+ENAV+ LAQRENSAAVQ+A +Y QQM Q+V+LP +TLQELLD+H EREAI +
Sbjct: 306 DLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEV 365
Query: 367 FMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSF 426
FM++SFKD +Q FQK+ K+ D +N E+S YC A L ++ L E++ G +
Sbjct: 366 FMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIY 425
Query: 427 SVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREK 486
S PGGH L+++ E ++ Y++ PRKG++A+EV Q++L+S+ + +ILQ+D+ALT+ EK
Sbjct: 426 SKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEK 485
Query: 487 AVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQI 546
+ K EA + E + L ++ +Q M+ +++ +E + Q +++ +++ L EQ
Sbjct: 486 KKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQ----MEIAKQNWLAEQQ 541
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDD 589
M E + Q L F+ + + +E+ +R T NDD
Sbjct: 542 KMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQR---TVNNDD 581
>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 587 bits (1513), Expect = e-167
Identities = 298/583 (51%), Positives = 413/583 (70%), Gaps = 8/583 (1%)
Query: 7 MLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFP 66
M P+CL+EN NEQL VNQ+A++IL I+QPVVVVAIVGLYRTGKSYLMN LAG+N GF
Sbjct: 7 MSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFS 66
Query: 67 LGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTF 126
+ STVQS TKGIW+WCVPHP+ PNHTLVLLDTEGLGDVEK D KND IFALA+LL STF
Sbjct: 67 VASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTF 126
Query: 127 VYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLE 186
VYN+++ I+ A++ LH VTELT+L+KA++SP D VED + SFFPD +WT+RDF L
Sbjct: 127 VYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLG 186
Query: 187 LKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLL 246
L+++G +T DEYLEN+L+ QG++ RVQ N PR CI++FFPK+KCF+FD P + K L
Sbjct: 187 LEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKK-L 245
Query: 247 ANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSG 306
A +E + + +L+P+F +Q FCSYIF+H+ TKTL GI V G+RL L +TYV AI+SG
Sbjct: 246 AQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTYVNAISSG 305
Query: 307 AVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAI 366
+PC+ENAV+ LAQRENSAAVQ+A +Y QQM Q+V+LP +TLQELLD+H EREAI +
Sbjct: 306 DLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEV 365
Query: 367 FMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSF 426
FM++SFKD +Q FQK+ K+ D +N E+S YC A L ++ L E++ G +
Sbjct: 366 FMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIY 425
Query: 427 SVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREK 486
S PGGH L+++ E ++ Y++ PRKG++A+EV Q++L+S+ + +ILQ+D+ALT+ EK
Sbjct: 426 SKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEK 485
Query: 487 AVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQI 546
+ K EA + E + L ++ +Q M+ +++ +E + Q +++ +++ L EQ
Sbjct: 486 KKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQ----MEIAKQNWLAEQQ 541
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDD 589
M E + Q L F+ + + +E+ +R T NDD
Sbjct: 542 KMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQR---TVNNDD 581
>gi|169160863 PREDICTED: similar to guanylate-binding protein 5
[Homo sapiens]
Length = 112
Score = 109 bits (273), Expect = 7e-24
Identities = 54/69 (78%), Positives = 62/69 (89%), Gaps = 1/69 (1%)
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375
+TLAQRENS A+QRAA++YSQQMAQR++ PTD LQELLDMH ACEREAIA+FMEHS + E
Sbjct: 1 MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
Query: 376 NQEFQKKFM 384
NQEFQKK M
Sbjct: 60 NQEFQKKLM 68
>gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 73.9 bits (180), Expect = 4e-13
Identities = 80/384 (20%), Positives = 158/384 (41%), Gaps = 43/384 (11%)
Query: 38 VVVVAIVGLYRTGKSYLMNHLAGQNH----------------GFPLGSTVQSETKGIWMW 81
VV V++ G +R GKS+LM+ + + GF + ET GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++ S VYN +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 ALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITED 197
L+ L TE L ++ +P F ++ VRD++ + +
Sbjct: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
Query: 198 EYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQL 257
++LE LK+ + +Q R+ I F CF+ P N + K++
Sbjct: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHPGLKVATNPNFDG-KLKEI 289
Query: 258 DPKFQEQTNIFCSYIFTHARTKTLRE--GITVTGNRLGTLAVTYVEAINSGAVPCLENAV 315
D +F + I ++ + + ++E G +T L Y++ +P ++ +
Sbjct: 290 DDEFIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSML 348
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRV--KLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A+ N AAV A D Y+++M + P +L H + E++ +F K
Sbjct: 349 QATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVK-K 407
Query: 374 DENQEFQKKFMETTMNKKGDFLLQ 397
+EF +++++ ++ + +Q
Sbjct: 408 MGGEEFSRRYLQQLESEIDELYIQ 431
>gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 73.9 bits (180), Expect = 4e-13
Identities = 80/384 (20%), Positives = 158/384 (41%), Gaps = 43/384 (11%)
Query: 38 VVVVAIVGLYRTGKSYLMNHLAGQNH----------------GFPLGSTVQSETKGIWMW 81
VV V++ G +R GKS+LM+ + + GF + ET GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++ S VYN +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 ALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITED 197
L+ L TE L ++ +P F ++ VRD++ + +
Sbjct: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
Query: 198 EYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQL 257
++LE LK+ + +Q R+ I F CF+ P N + K++
Sbjct: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHPGLKVATNPNFDG-KLKEI 289
Query: 258 DPKFQEQTNIFCSYIFTHARTKTLRE--GITVTGNRLGTLAVTYVEAINSGAVPCLENAV 315
D +F + I ++ + + ++E G +T L Y++ +P ++ +
Sbjct: 290 DDEFIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSML 348
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRV--KLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A+ N AAV A D Y+++M + P +L H + E++ +F K
Sbjct: 349 QATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVK-K 407
Query: 374 DENQEFQKKFMETTMNKKGDFLLQ 397
+EF +++++ ++ + +Q
Sbjct: 408 MGGEEFSRRYLQQLESEIDELYIQ 431
>gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]
Length = 558
Score = 73.9 bits (180), Expect = 4e-13
Identities = 80/384 (20%), Positives = 158/384 (41%), Gaps = 43/384 (11%)
Query: 38 VVVVAIVGLYRTGKSYLMNHLAGQNH----------------GFPLGSTVQSETKGIWMW 81
VV V++ G +R GKS+LM+ + + GF + ET GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++ S VYN +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 ALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITED 197
L+ L TE L ++ +P F ++ VRD++ + +
Sbjct: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
Query: 198 EYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQL 257
++LE LK+ + +Q R+ I F CF+ P N + K++
Sbjct: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHPGLKVATNPNFDG-KLKEI 289
Query: 258 DPKFQEQTNIFCSYIFTHARTKTLRE--GITVTGNRLGTLAVTYVEAINSGAVPCLENAV 315
D +F + I ++ + + ++E G +T L Y++ +P ++ +
Sbjct: 290 DDEFIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSML 348
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRV--KLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A+ N AAV A D Y+++M + P +L H + E++ +F K
Sbjct: 349 QATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVK-K 407
Query: 374 DENQEFQKKFMETTMNKKGDFLLQ 397
+EF +++++ ++ + +Q
Sbjct: 408 MGGEEFSRRYLQQLESEIDELYIQ 431
>gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]
Length = 583
Score = 66.6 bits (161), Expect = 7e-11
Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 44/349 (12%)
Query: 13 LVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHL-------------A 59
L E EQ+L+ Q+ I+ L +VVV++ G +R GKS+L++ +
Sbjct: 75 LDEEALEQILL-QEHIRDLN-----IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIG 128
Query: 60 GQNH---GFPLGSTVQSETKGIWMW----CVPHPSKPNHTLVLLDTEGLGDVEKGDPKND 112
G N GF + ET GI +W + P+ ++L+DT+G D + K+
Sbjct: 129 GNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDC 187
Query: 113 SWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSF 172
+ +FAL+ + S VYN I L+ L TE L + +P
Sbjct: 188 ATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKP------------ 235
Query: 173 FPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRK 232
F ++ +RD++ + + ++LE L++ Q + +Q R+ I F
Sbjct: 236 FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLG 292
Query: 233 CFVFDRPTNDKDLLANIEKVSEKQLDPKF-QEQTNIFCSYIFTHARTKTLREGITVTGNR 291
CF+ P + + K +D F +E N+ + + G VT
Sbjct: 293 CFLLPHPGLKVATNPSFDG-RLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
Query: 292 LGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQ 340
L Y++ +P ++ + A+ N AAV A D Y + M Q
Sbjct: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQ 400
>gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
Length = 579
Score = 66.6 bits (161), Expect = 7e-11
Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 44/349 (12%)
Query: 13 LVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHL-------------A 59
L E EQ+L+ Q+ I+ L +VVV++ G +R GKS+L++ +
Sbjct: 75 LDEEALEQILL-QEHIRDLN-----IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIG 128
Query: 60 GQNH---GFPLGSTVQSETKGIWMW----CVPHPSKPNHTLVLLDTEGLGDVEKGDPKND 112
G N GF + ET GI +W + P+ ++L+DT+G D + K+
Sbjct: 129 GNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDC 187
Query: 113 SWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSF 172
+ +FAL+ + S VYN I L+ L TE L + +P
Sbjct: 188 ATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKP------------ 235
Query: 173 FPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRK 232
F ++ +RD++ + + ++LE L++ Q + +Q R+ I F
Sbjct: 236 FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLG 292
Query: 233 CFVFDRPTNDKDLLANIEKVSEKQLDPKF-QEQTNIFCSYIFTHARTKTLREGITVTGNR 291
CF+ P + + K +D F +E N+ + + G VT
Sbjct: 293 CFLLPHPGLKVATNPSFDG-RLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
Query: 292 LGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQ 340
L Y++ +P ++ + A+ N AAV A D Y + M Q
Sbjct: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQ 400
>gi|45827806 atlastin 3 [Homo sapiens]
Length = 541
Score = 65.9 bits (159), Expect = 1e-10
Identities = 86/384 (22%), Positives = 150/384 (39%), Gaps = 50/384 (13%)
Query: 1 MESGPKMLAPVCLVENNNEQLLVNQQA---IQILEKISQ-PVVVVAIVGLYRTGKSYLMN 56
MES V LV+ + ++++A I + + I VVVV++ G +R GKS++++
Sbjct: 19 MESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILD 78
Query: 57 HL---------AGQNH----------GFPLGSTVQSETKGIWMWC----VPHPSKPNHTL 93
+ +G ++ GF ET GI +W V P +
Sbjct: 79 FMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAV 138
Query: 94 VLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIK 153
VL+DT+G D + K+ + IFAL+ + S +YN I L+QL TE L
Sbjct: 139 VLMDTQGAFD-SQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAM 197
Query: 154 AKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPR 213
+ +P F ++ VRD++ + + +L+ L++ + +
Sbjct: 198 DEIFQKP------------FQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEE 245
Query: 214 VQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIF 273
+Q R I F CF+ P + + K + +F+EQ Y+
Sbjct: 246 IQN---VRNHIHSCFSDVTCFLLPHPGLQVATSPDFDG-KLKDIAGEFKEQLQALIPYVL 301
Query: 274 THARTKTLR-EGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAAD 332
++ G VT L Y++ +P ++ + A+ N AA A D
Sbjct: 302 NPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKD 361
Query: 333 YYSQQM-----AQRVKLPTDTLQE 351
Y M ++ L D L+E
Sbjct: 362 IYYNNMEEVCGGEKPYLSPDILEE 385
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/277 (19%), Positives = 117/277 (42%), Gaps = 28/277 (10%)
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375
+ L + E S + + ++ LP LQ D H E ++++ ++ +E
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKELQSVSAKLQAQV-EE 287
Query: 376 NQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLY 435
N+ + + +N++ + + +E +Q + K+ E + + E +
Sbjct: 288 NELWNR------LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK--------IREQ 333
Query: 436 METKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKK 495
E R E+ W+ K + +E+ E +EE + + ++ + + E+ + +
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
Query: 496 EAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV 555
E EK QE K + QE++Q+ EA+ ++E I + +EK++ + + + R
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR------------ 441
Query: 556 QNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPW 592
Q + +HE K + EE E + R + + + W
Sbjct: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Score = 46.2 bits (108), Expect = 9e-05
Identities = 37/210 (17%), Positives = 100/210 (47%), Gaps = 17/210 (8%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
++E ++ ++K E ++ + + +E ++ + K+ E K + +
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE----KIHEQE 450
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
K+ E K + +++ W+ K + +E++++ +E + + +K EK V R
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQ--------KEKMHEQEKIRKQEEK---VWR 499
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHT 552
+++ ++E+++ +Q +E+ + E + + ++E I + +EK++ + E + ++ M E
Sbjct: 500 QEEKMHDQEEKIREQ--EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 553 QKVQNDWLHEGFKKKYEEMNAEISQFKRMI 582
+K+Q ++K E +I + K I
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/172 (20%), Positives = 84/172 (48%), Gaps = 13/172 (7%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
K +QE + + E M ++ + + + EE ++ + K+ E + + E G
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEK-IREQEEKIREQEEMMQEQEEK-----MGEQ 556
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
+ M+ +E++ + ++ + K +E ++ E EE I + ++ + ++E+ +
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ----EEKIWEQEEKIREQEEMMQEQE 612
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKE---NIAQLKEKLQMEREHL 541
K E++ ++K+QEQ+++M Q++ E + Q +EK+Q +EHL
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/145 (22%), Positives = 74/145 (51%), Gaps = 13/145 (8%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
+ +E+I + ++ R+ K +E ++ E EE I + ++ + ++E+ + E
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQ----EEKIREQEEMMQEQEEKMG------E 555
Query: 497 AAEKEQELLKQKLQEQQ-QQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV 555
EK QE K + QE++ ++ E + + +KE I + +EK+ + E + ++ MM E +K+
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
Query: 556 QNDWLHEGFKKKYEEMNAEISQFKR 580
E ++ E+M + + +R
Sbjct: 616 WEQ--EEKMCEQEEKMQEQEEKMRR 638
Score = 40.0 bits (92), Expect = 0.007
Identities = 24/128 (18%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAK-- 494
E K R +++ Q + + +E + E EE I + ++ + ++++ + K
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Query: 495 -KEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQ 553
+E +EQE + Q+ +E+ + E + ++E + + +EK++ + E + +++ + + +
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 655
Query: 554 KVQNDWLH 561
K+Q H
Sbjct: 656 KMQEHQEH 663
Score = 39.3 bits (90), Expect = 0.011
Identities = 29/140 (20%), Positives = 78/140 (55%), Gaps = 14/140 (10%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVI---EESILQSDKALTDREKAVAVDRA 493
E +E++ + ++ + K +E ++ E + ++ EE + + ++ + ++EK + R
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK---MRRQ 569
Query: 494 KKEAAEKEQEL--LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEH 551
+++ E+E+++ K+K++EQ++++ Q+ E I + +E +Q + E + ++ M E
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQE----EKIREQEEMMQEQEEKMWEQEEKMCEQ 625
Query: 552 TQKVQNDWLHEGFKKKYEEM 571
+K+Q E +++ E+M
Sbjct: 626 EEKMQEQ--EEKMRRQEEKM 643
Score = 36.6 bits (83), Expect = 0.072
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 436 METKERI-EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAK 494
M +E+I EQ+ + + ++ +E Q EE I + ++ + ++EK + K
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Query: 495 KEAAEKEQELLKQKLQEQQQQMEAQDKSR-KENIAQLKEKL-QMEREHLLREQIMMLEHT 552
EK +E ++K QEQ++ ++K R +E I + KEK+ + E+ E++ E
Sbjct: 446 IHEQEKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 553 QKVQNDWLHEGFKKKYEE 570
Q + + E +K + +
Sbjct: 504 MHDQEEKIREQEEKMWRQ 521
Score = 35.4 bits (80), Expect = 0.16
Identities = 27/144 (18%), Positives = 72/144 (50%), Gaps = 24/144 (16%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVA-----VD 491
E K R +++ + + ++ +E + E +M +E +Q + + +E+ + +
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 492 RAKKEAAEKEQELLKQ--KLQEQQQQMEAQDKS---RKENIAQLKEKLQMEREHLLREQI 546
K++ E+E+++ +Q K++EQ++ M+ Q++ ++E + + +EK+Q + E + R++
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 547 --------------MMLEHTQKVQ 556
M EH + ++
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 35.0 bits (79), Expect = 0.21
Identities = 26/128 (20%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
Query: 396 LQNEESSVQYCQAKLNELSKGLMES--ISAGSFSVPGGHKLYMETKERI---EQDYWQVP 450
++ +E +Q + K+ E + + E + + + E KE+I E+ W+
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 451 RKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQ 510
K + +E+ Q E EE + + ++ + ++E+ + K E ++K+Q
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Query: 511 EQQQQMEA 518
E Q+ +EA
Sbjct: 659 EHQEHLEA 666
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/66 (25%), Positives = 37/66 (56%)
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT A++++ + ++E + KLQE+ Q +E++ + N+ +LK KL+ +
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 257
Query: 541 LLREQI 546
L ++Q+
Sbjct: 258 LPQQQL 263
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/232 (21%), Positives = 116/232 (50%), Gaps = 25/232 (10%)
Query: 360 EREAIAIFM------EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESS----------- 402
ER+A+++ + + K++N + Q+K ++ ++K + L +E
Sbjct: 189 ERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEKSEIQLNVKELKRKLERAKLLLP 247
Query: 403 VQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQR 462
Q QA+ + L K L +S+SA + ++L+ ++ E+ W+ K + +E Q
Sbjct: 248 QQQLQAEADHLGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 463 FLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQEL--LKQKLQEQQQQMEAQD 520
E EE + + ++ + ++E+ + R ++ EKE+++ L++K+ EQ++ E ++
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Query: 521 KSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV--QNDWLHEGFKKKYEE 570
K ++E + +EK Q + + R++ + E +K+ Q + + E +K E+
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/269 (18%), Positives = 117/269 (43%), Gaps = 26/269 (9%)
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375
+ L + E S + + ++ LP LQ D H E ++++ ++ +E
Sbjct: 218 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKELQSVSAKLQAQV-EE 275
Query: 376 NQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLY 435
N+ + + +N++ + + +E +Q + K+ E + + E
Sbjct: 276 NELWNR------LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ--------------- 314
Query: 436 METKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKK 495
E R E+ W+ K + +E+ E +EE + + +K EK ++ ++
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 496 EAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV 555
+ +EQE + +E+ ++ E + + ++E + + +EK+ + E + ++ M E +K+
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 556 --QNDWLHEGFKKKYEEMNAEISQFKRMI 582
Q + + E +KK E +I + + M+
Sbjct: 435 RRQEEKIREQ-EKKIREQEEKIREQEEMM 462
Score = 44.7 bits (104), Expect = 3e-04
Identities = 41/224 (18%), Positives = 101/224 (45%), Gaps = 17/224 (7%)
Query: 369 EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV 428
E K QE + + E M +K + + + EE + + K+ EL + + E
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMHEQ-------- 356
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAV 488
K+ + ++R E++ + K + + R E EE I + ++ + ++E+ +
Sbjct: 357 ---EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 489 AVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDK---SRKENIAQLKEKLQMEREHLLREQ 545
K E+E + ++K++ Q++++ Q+K ++E I + +E +Q + E + ++
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 546 IMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDD 589
M E K+Q E +++ E++ + + + + + +
Sbjct: 474 GKMCEQEAKMQEQ--EEKMRRQEEKIREQEKKIREQEEKIREQE 515
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/214 (17%), Positives = 98/214 (45%), Gaps = 31/214 (14%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
++E ++ ++K E ++ + + +E ++ + K+ E + + E
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ------------ 409
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
E E+ W+ + + +E +R E E+ I + ++ + ++E+ +
Sbjct: 410 ---EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM--QE 464
Query: 493 AKKEAAEKEQELLKQ--KLQEQQQQMEAQD----------KSRKENIAQLKEKLQMEREH 540
+++ E+E ++ +Q K+QEQ+++M Q+ + ++E I + +E +Q + E
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 541 LLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAE 574
+ ++ M E +K+Q E +++ E+M +
Sbjct: 525 MWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMREQ 556
Score = 43.1 bits (100), Expect = 8e-04
Identities = 39/203 (19%), Positives = 91/203 (44%), Gaps = 20/203 (9%)
Query: 360 EREAIAIFMEHSFKDENQEF--QKKFMETTMNKKGDF--LLQNEESSVQYCQAKLNELSK 415
E+EA E +++ ++ Q++ M+ K G+ + +E +Q + K+ +
Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 416 GLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESIL 475
+ E K E +E+I + + + K E + E + ++E
Sbjct: 440 KIREQ-----------EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE--- 485
Query: 476 QSDKALTDREKAVAVDRAKKEAAEK--EQELLKQKLQEQQQQMEAQDKSRKENIAQLKEK 533
Q +K EK ++ +E EK EQE + Q+ +E+ + E + ++E + + +EK
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Query: 534 LQMEREHLLREQIMMLEHTQKVQ 556
++ + E + +++ + + +K+Q
Sbjct: 546 MRRQEEKMREQEVRLRQQEEKMQ 568
Score = 36.2 bits (82), Expect = 0.095
Identities = 35/148 (23%), Positives = 78/148 (52%), Gaps = 13/148 (8%)
Query: 439 KERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAA 498
+E+ E Q + G + ++++++ E Q E+ Q +K RE+ + +++
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI---REQEKKIREQEEKIR 456
Query: 499 EKEQELLKQ--KLQEQQQQM---EAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQ 553
E+E+ + +Q K+ EQ+ +M EA+ + ++E + + +EK++ E+E +REQ E
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR-EQEKKIREQ----EEKI 511
Query: 554 KVQNDWLHEGFKKKYEEMNAEISQFKRM 581
+ Q + + E +K +E+ Q ++M
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/66 (25%), Positives = 37/66 (56%)
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT A++++ + ++E + KLQE+ Q +E++ + N+ +LK KL+ +
Sbjct: 186 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 245
Query: 541 LLREQI 546
L ++Q+
Sbjct: 246 LPQQQL 251
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/277 (19%), Positives = 116/277 (41%), Gaps = 28/277 (10%)
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375
+ L + E S + + ++ LP LQ D H E ++++ ++ +E
Sbjct: 291 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKELQSVSAKLQAQV-EE 348
Query: 376 NQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLY 435
N+ + + +N++ + + +E +Q + K+ E + + E +
Sbjct: 349 NELWNR------LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK--------IREQ 394
Query: 436 METKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKK 495
E R E+ W+ K + +E+ E EE + + ++ + + E+ + +
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 496 EAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV 555
E EK QE K + QE++Q+ EA+ ++E I + +EK++ + E + R
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR------------ 502
Query: 556 QNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPW 592
Q + +HE K + EE E + R + + + W
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/234 (17%), Positives = 115/234 (49%), Gaps = 29/234 (12%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
++E ++ ++K E ++ + + +E ++ + K+ E + + +
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE----KIHEQE 511
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVI---EESILQSDKALTDREK 486
K+ E K + +++ W+ K + +E++ ++ E + I EE + + ++ + D+E+
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 487 AVA-----VDRAKKEAAEKEQELLKQ--KLQEQQQQMEAQDK---SRKENIAQLKEKLQM 536
+ V R +++ E+E+++ +Q K++EQ++ + Q++ ++E + + +EK+Q
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 537 EREHLLREQIMMLEHTQKV---------QNDWLHEGFKKKYEEMNAEISQFKRM 581
+ E + R++ + E +K+ Q + + E +K +E+ Q ++M
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/155 (21%), Positives = 76/155 (49%), Gaps = 22/155 (14%)
Query: 437 ETKERI---EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVA---- 489
E +E+I E+ W+ K +E + E EE I + ++ + ++E+ +
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 490 -VDRAKKEAAEKEQELLKQ--KLQEQQQQMEAQD----------KSRKENIAQLKEKLQM 536
+++ E+E+++ +Q K+QEQ+++M Q+ + ++E I + +E +Q
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Query: 537 EREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEM 571
+ E + ++ M E +K+Q E +++ E+M
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKM 699
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/127 (21%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E +E+I + + K E ++ E + ++E Q +K EK ++ +E
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE---QEEKMRRQEEKIREQEKKIRE 652
Query: 497 AAEK--EQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQK 554
EK EQE + Q+ +E+ + E + ++E + + +EK++ + E + +++ + + +K
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Query: 555 VQNDWLH 561
+Q H
Sbjct: 713 MQEHQEH 719
Score = 40.0 bits (92), Expect = 0.007
Identities = 34/148 (22%), Positives = 71/148 (47%), Gaps = 15/148 (10%)
Query: 436 METKERI-EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAK 494
M +E+I EQ+ + + ++ +E Q EE I + ++ + ++E+ + K
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Query: 495 KEAAEKEQELLKQKLQEQQQQMEAQDKSR--------KENIAQLKEKLQMEREHLLREQI 546
EK +E ++K QEQ++ ++K R KE I + +EK++ + E + R++
Sbjct: 507 IHEQEKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 547 MMLEHTQKVQND----WLHEGFKKKYEE 570
M + +K++ W E ++ EE
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEE 592
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/115 (24%), Positives = 59/115 (51%), Gaps = 10/115 (8%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVA-----VD 491
E + E+ + K + +E Q E EE I + +K + ++E+ + +
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 492 RAKKEAAEKEQELLKQ--KLQEQQQQMEAQDKSRKE---NIAQLKEKLQMEREHL 541
+++ E+E+++ +Q K+QEQ+++M Q++ E + Q +EK+Q +EHL
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 36.6 bits (83), Expect = 0.072
Identities = 30/165 (18%), Positives = 83/165 (50%), Gaps = 17/165 (10%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E +E+I + ++ R+ K E + E + +E + + ++ + ++E+ + R K++
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE---IWRQKEK 544
Query: 497 AAEKEQELLKQ---------KLQEQQQQMEAQDKS---RKENIAQLKEKLQMEREHLLRE 544
E+E+++ KQ K+ +Q++++ Q++ ++E I + +EK++ + E + +
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 545 QIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDD 589
+ M E +K+ E ++ E+M + + +R + + +
Sbjct: 605 EEMTQEQEEKMGEQ--EEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/66 (25%), Positives = 37/66 (56%)
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT A++++ + ++E + KLQE+ Q +E++ + N+ +LK KL+ +
Sbjct: 259 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 318
Query: 541 LLREQI 546
L ++Q+
Sbjct: 319 LPQQQL 324
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2453
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2454 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2508
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2628
Query: 600 LADEL 604
D L
Sbjct: 2629 GRDAL 2633
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1513 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1623
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1624 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1670
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1671 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1731 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1761
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2150 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2205
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2261
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2262 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2316
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2317 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2375 QLEMSAEAE 2383
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2149
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2150 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2209
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2210 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2266
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2326
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2327 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2372
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2373 QRQLEMSAEAERLK 2386
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1238 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1292
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1293 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1352
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1412
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1413 QQKRSIQEELQQLRQ 1427
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1393
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1452
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1453 E--IRVVRLQLEATER 1466
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2173
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2174 AEQTLRQKAQVEQ 2186
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2344 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2403
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2404 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2457
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2458 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2512
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2513 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2572
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2573 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2632
Query: 600 LADEL 604
D L
Sbjct: 2633 GRDAL 2637
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1517 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1576
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1577 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1627
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1628 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1674
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1675 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1734
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1735 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1765
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2154 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2209
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2210 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2265
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2266 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2320
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2321 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2378
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2379 QLEMSAEAE 2387
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2153
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2154 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2213
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2214 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2270
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2271 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2330
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2331 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2376
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2377 QRQLEMSAEAERLK 2390
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1242 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1296
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1297 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1356
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1357 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1416
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1417 QQKRSIQEELQQLRQ 1431
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1339 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1397
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1398 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1456
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1457 E--IRVVRLQLEATER 1470
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2065 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2124
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2177
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2178 AEQTLRQKAQVEQ 2190
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2453
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2454 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2508
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2628
Query: 600 LADEL 604
D L
Sbjct: 2629 GRDAL 2633
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1513 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1623
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1624 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1670
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1671 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1730
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1731 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1761
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2150 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2205
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2206 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2261
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2262 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2316
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2317 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2375 QLEMSAEAE 2383
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2149
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2150 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2209
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2210 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2266
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2326
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2327 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2372
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2373 QRQLEMSAEAERLK 2386
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1238 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1292
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1293 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1352
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1353 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1412
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1413 QQKRSIQEELQQLRQ 1427
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1393
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1452
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1453 E--IRVVRLQLEATER 1466
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2173
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2174 AEQTLRQKAQVEQ 2186
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2308 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2367
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2368 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2421
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2422 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2476
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2477 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2536
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2537 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2596
Query: 600 LADEL 604
D L
Sbjct: 2597 GRDAL 2601
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1481 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1540
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1541 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1591
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1592 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1638
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1639 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1698
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1699 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1729
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2118 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2173
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2174 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2229
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2230 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2284
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2285 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2342
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2343 QLEMSAEAE 2351
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2059 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2117
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2118 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2177
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2178 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2234
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2235 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2294
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2295 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2340
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2341 QRQLEMSAEAERLK 2354
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1206 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1260
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1261 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1320
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1321 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1380
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1381 QQKRSIQEELQQLRQ 1395
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1303 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1361
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1362 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1420
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1421 E--IRVVRLQLEATER 1434
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2029 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2088
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2141
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2142 AEQTLRQKAQVEQ 2154
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2477 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2536
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2537 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2590
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2591 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2645
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2646 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2705
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2706 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2765
Query: 600 LADEL 604
D L
Sbjct: 2766 GRDAL 2770
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1650 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1709
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1710 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1760
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1761 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1807
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1808 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1867
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1868 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1898
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2287 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2342
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2343 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2398
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2399 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2453
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2454 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2511
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2512 QLEMSAEAE 2520
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2228 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2286
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2287 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2346
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2347 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2403
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2404 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2463
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2464 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2509
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2510 QRQLEMSAEAERLK 2523
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1375 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1429
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1430 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1489
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1490 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1549
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1550 QQKRSIQEELQQLRQ 1564
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1472 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1530
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1531 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1589
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1590 E--IRVVRLQLEATER 1603
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2198 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2257
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2310
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2311 AEQTLRQKAQVEQ 2323
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2318 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2377
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2378 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2431
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2432 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2486
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2487 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2546
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2547 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2606
Query: 600 LADEL 604
D L
Sbjct: 2607 GRDAL 2611
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1491 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1550
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1551 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1601
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1602 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1648
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1649 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1708
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1709 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1739
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2128 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2183
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2184 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2239
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2240 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2294
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2295 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2352
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2353 QLEMSAEAE 2361
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2069 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2127
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2128 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2187
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2188 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2244
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2245 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2304
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2305 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2350
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2351 QRQLEMSAEAERLK 2364
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1216 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1270
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1271 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1330
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1331 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1390
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1391 QQKRSIQEELQQLRQ 1405
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1313 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1371
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1372 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1430
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1431 E--IRVVRLQLEATER 1444
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2039 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2098
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2099 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2151
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2152 AEQTLRQKAQVEQ 2164
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2326 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2385
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2386 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2439
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2440 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2494
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2495 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2554
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2555 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2614
Query: 600 LADEL 604
D L
Sbjct: 2615 GRDAL 2619
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1499 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1558
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1559 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1609
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1610 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1656
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1657 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1716
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1717 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1747
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2136 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2191
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2192 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2247
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2248 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2302
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2303 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2360
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2361 QLEMSAEAE 2369
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2077 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2135
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2136 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2195
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2196 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2252
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2253 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2312
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2313 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2358
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2359 QRQLEMSAEAERLK 2372
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1224 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1278
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1279 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1338
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1339 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1398
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1399 QQKRSIQEELQQLRQ 1413
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1321 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1379
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1380 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1438
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1439 E--IRVVRLQLEATER 1452
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2047 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2106
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2107 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2159
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2160 AEQTLRQKAQVEQ 2172
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/305 (21%), Positives = 144/305 (47%), Gaps = 32/305 (10%)
Query: 321 RENSAAVQRAADYYSQQMAQRVKLPTDTL----QELLDMHAACEREAIAIF----MEHSF 372
+E + +Q + +QQ+A+ + TL Q L+M A ER + + +
Sbjct: 2367 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2426
Query: 373 KDENQEFQKKFMETTMN-KKGDFLLQNEESSVQYCQAKLNEL---SKGLMESISAGSFSV 428
+++ Q F+K+ E + + Q + + VQ + + + ++ L E+I+
Sbjct: 2427 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIA------ 2480
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQ-RFLESQMVIEESILQSDKALTDREKA 487
+L E KE+++Q+ + K + + V Q + L+ +++S L +L RE+
Sbjct: 2481 ----ELERE-KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERF 2535
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQ-DKSRKENIAQLKE--KLQMEREHLLR- 543
+ ++AK E +++ Q+L+E+QQ+ + Q ++ R+ +A ++E + Q E E +R
Sbjct: 2536 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2595
Query: 544 --EQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIA--RTLDN 599
E++ LE ++ Q + L E ++ E++ Q + + ++ +A +TL N
Sbjct: 2596 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2655
Query: 600 LADEL 604
D L
Sbjct: 2656 GRDAL 2660
Score = 38.9 bits (89), Expect = 0.015
Identities = 54/273 (19%), Positives = 119/273 (43%), Gaps = 31/273 (11%)
Query: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
A + LA R + A + Q + ++L + + L + + +E + +
Sbjct: 1540 AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1599
Query: 374 DENQEFQKK---FMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG 430
E Q K F E T + LQ E +V + + ++ E+ A
Sbjct: 1600 SAEAELQSKRASFAEKTAQLERS--LQEEHVAVAQLREEAERRAQQQAEAERA------- 1650
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAV 490
E ER E + WQ+ KA E + L+++ V ++ L +A +++K A
Sbjct: 1651 -----REEAER-ELERWQL-----KANEALRLRLQAEEVAQQKSLAQAEA--EKQKEEAE 1697
Query: 491 DRAKKEAAEKEQELLKQKLQEQQQQMEAQ--DKSRKENIAQLKE--KLQMEREHLLREQI 546
A++ +EQ + +++L EQ+ + + Q + + ++ +A +E +L+ E E +++
Sbjct: 1698 REARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQ 1757
Query: 547 MMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
++ E ++Q + +K +E+ AE+++ +
Sbjct: 1758 LLEEELARLQRE--AAAATQKRQELEAELAKVR 1788
Score = 38.1 bits (87), Expect = 0.025
Identities = 60/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 319 AQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDEN-- 376
AQ E +A Q+ A +M + K TL++ + E + + +E + +N
Sbjct: 2177 AQAEQAALRQKQAA--DAEMEKHKKFAEQTLRQKAQVEQ--ELTTLRLQLEETDHQKNLL 2232
Query: 377 -QEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV-----PG 430
+E Q+ E T + ++ E SV+ ++ ELSK L I A + ++
Sbjct: 2233 DEELQRLKAEATEAARQRSQVEEELFSVR---VQMEELSK-LKARIEAENRALILRDKDN 2288
Query: 431 GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDR---EKA 487
+ E E+++Q + R V A+E + + + EE + Q +AL ++ EK
Sbjct: 2289 TQRFLQEEAEKMKQVAEEAARLSVAAQEAARL----RQLAEEDLAQQ-RALAEKMLKEKM 2343
Query: 488 VAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM 547
AV A + AE E LL+Q+ + Q+Q + +++ QL E+ Q + L E+
Sbjct: 2344 QAVQEATRLKAEAE--LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2401
Query: 548 MLEHTQKVQ 556
LE + + +
Sbjct: 2402 QLEMSAEAE 2410
Score = 37.4 bits (85), Expect = 0.042
Identities = 71/314 (22%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 301 EAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACE 360
E V A + Q E + ++++A+ +Q AQ + + L++ + AA
Sbjct: 2118 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ-AQAAAEKLRKEAEQEAARR 2176
Query: 361 REAI-AIFMEHSFKDENQEFQKKFMETTMNKKGD-------FLLQNEESSVQ--YCQAKL 410
+A A + D E KKF E T+ +K LQ EE+ Q +L
Sbjct: 2177 AQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEEL 2236
Query: 411 NELSKGLMESISAGS------FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFL 464
L E+ S FSV + + K RIE + + ++ K+ QRFL
Sbjct: 2237 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI---LRDKDNTQRFL 2293
Query: 465 ESQMVIEESILQSDKALT--DREKAVAVDRAKKEAAEKE---QELLKQKLQE-------- 511
+ + + + + L+ +E A A+++ A++ +++LK+K+Q
Sbjct: 2294 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2353
Query: 512 ------QQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFK 565
QQQ+ AQ+++R +LQ ++E + ++ + E TQ Q E +
Sbjct: 2354 AEAELLQQQKELAQEQAR---------RLQEDKEQMAQQ---LAEETQGFQRTL--EAER 2399
Query: 566 KKYEEMNAEISQFK 579
++ EM+AE + K
Sbjct: 2400 QRQLEMSAEAERLK 2413
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/195 (23%), Positives = 88/195 (45%), Gaps = 12/195 (6%)
Query: 352 LLDMHAACE--REAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAK 409
L D A E R+ A+ E E E ++F + +N D+ LQ V Y +A+
Sbjct: 1265 LADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQ----LVTY-KAQ 1319
Query: 410 LNEL-SKGLMESISAGSFSVPGGH---KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLE 465
L + S + +GS SV + + + + Y + + ++ E +R E
Sbjct: 1320 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1379
Query: 466 SQMVIEESILQSDKALTDREKAVAVDRAKKEA-AEKEQELLKQKLQEQQQQMEAQDKSRK 524
Q E L +A ++++ +A A+ +A AE+E + L+Q++QE+ + E +
Sbjct: 1380 QQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQ 1439
Query: 525 ENIAQLKEKLQMERE 539
+ ++E+LQ R+
Sbjct: 1440 QQKRSIQEELQQLRQ 1454
Score = 35.0 bits (79), Expect = 0.21
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVF---QRFLESQMVIEESILQSDKALTDREKAVA 489
K ET R+E++ ++ + +E + LE Q + E+ Q+ KA +RE
Sbjct: 1362 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-KAQAEREAKEL 1420
Query: 490 VDRAKKEAAEKEQELL-----KQKLQEQQQQM------EAQDKSRKENIAQLKEKLQMER 538
R ++E +E+ + K+ +QE+ QQ+ E Q K+R+ A+ + +L++E
Sbjct: 1421 QQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEE 1479
Query: 539 EHLLREQIMMLEHTQK 554
E +R + LE T++
Sbjct: 1480 E--IRVVRLQLEATER 1493
Score = 34.7 bits (78), Expect = 0.27
Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 455 KAKEVFQRFLESQMVIEE----------SILQSDKALTDREKAVAVDRAKKEAAEKEQEL 504
K +E+ Q + Q V+++ + ++++A E+ A R + E AE+ ++
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2147
Query: 505 LKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGF 564
+++ Q + Q A +K RKE + + Q E+ L ++Q E + H+ F
Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEK-------HKKF 2200
Query: 565 KKKYEEMNAEISQ 577
++ A++ Q
Sbjct: 2201 AEQTLRQKAQVEQ 2213
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/140 (21%), Positives = 75/140 (53%), Gaps = 4/140 (2%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E +E+ ++ W+ +K + E + E EE I + ++ + D+E+ + K +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 497 AAEKEQELLKQKLQEQQQQMEAQDKS--RKENIAQLKEKLQMEREHLLREQIMMLEHTQK 554
E++ + ++K+Q Q+++++ Q++ R+E + + +EK+ + E + R++ M E +K
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 555 VQNDWLHEGFKKKYEEMNAE 574
+Q E +++ E+M +
Sbjct: 519 MQEQ--EEKMQRQEEKMREQ 536
Score = 49.3 bits (116), Expect = 1e-05
Identities = 42/200 (21%), Positives = 97/200 (48%), Gaps = 20/200 (10%)
Query: 369 EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV 428
E K QE +K + + ++ D +Q +E + + K+ E + E +
Sbjct: 357 EQEEKIREQE-EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE--- 412
Query: 429 PGGHKLYMETKERI---EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDRE 485
K E E+I E++ W+ K + +E+ Q E +EE + + ++ + ++E
Sbjct: 413 ----KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 486 KAVAVDRAKKEAAE----KEQELLKQ--KLQEQQQQMEAQDKS---RKENIAQLKEKLQM 536
+ + K + E ++++LLKQ K+ EQ+++M Q++ ++E + + +EK+Q
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 537 EREHLLREQIMMLEHTQKVQ 556
+ E + +++ + + +K+Q
Sbjct: 529 QEEKMREQEVRLWQQEEKMQ 548
Score = 44.3 bits (103), Expect = 3e-04
Identities = 54/312 (17%), Positives = 130/312 (41%), Gaps = 31/312 (9%)
Query: 291 RLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQ 350
R+GT + ++ ++ N + +E +A +Q + ++ D +
Sbjct: 187 RMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR 246
Query: 351 ELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKL 410
+L ++ + + + K+ K + N+ + L Q +E + + K+
Sbjct: 247 KLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI 306
Query: 411 NELSKGLMES---ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQ 467
E + + E I + + E +E+I + ++ R+ K +E ++ E +
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
Query: 468 MVI---EESILQSDKALTDREKAVAVDRAK-KEAAEKEQELL----------KQKLQEQQ 513
+ EE I + D+ + ++E+ + K +E EK QE + +K++EQ+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 514 QQMEAQDKS----------RKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQND----W 559
++M Q++ ++E + +++EK+Q E E + ++ + +K+Q W
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 560 LHEGFKKKYEEM 571
E K+ E++
Sbjct: 487 RQEKLLKQEEKI 498
Score = 38.5 bits (88), Expect = 0.019
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 18/174 (10%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
+ E + +K + + ++ D ++ +E + + K+ EL + + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ------------ 446
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
E +E+ + K + +E QR E EE + +K L EK +
Sbjct: 447 ---EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQL--KEKLQMEREHLLRE 544
EK E ++K+QEQ+++M+ Q++ +E +L +E+ E+E L+E
Sbjct: 504 KMWRQEEKMWEQ-EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 34.3 bits (77), Expect = 0.36
Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 9/113 (7%)
Query: 484 REKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLR 543
REK++A D + +E E L +K + ++ E D E+ Q KE L+ L
Sbjct: 54 REKSIA-DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPD 112
Query: 544 EQIMM---LEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWI 593
++ + + H +K +D + FKK+ E+MN + F++ + K PW+
Sbjct: 113 DEAIEDAGVSHVKK-NSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK----PWL 160
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/140 (21%), Positives = 75/140 (53%), Gaps = 4/140 (2%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E +E+ ++ W+ +K + E + E EE I + ++ + D+E+ + K +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 497 AAEKEQELLKQKLQEQQQQMEAQDKS--RKENIAQLKEKLQMEREHLLREQIMMLEHTQK 554
E++ + ++K+Q Q+++++ Q++ R+E + + +EK+ + E + R++ M E +K
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 555 VQNDWLHEGFKKKYEEMNAE 574
+Q E +++ E+M +
Sbjct: 519 MQEQ--EEKMQRQEEKMREQ 536
Score = 49.3 bits (116), Expect = 1e-05
Identities = 42/200 (21%), Positives = 97/200 (48%), Gaps = 20/200 (10%)
Query: 369 EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV 428
E K QE +K + + ++ D +Q +E + + K+ E + E +
Sbjct: 357 EQEEKIREQE-EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE--- 412
Query: 429 PGGHKLYMETKERI---EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDRE 485
K E E+I E++ W+ K + +E+ Q E +EE + + ++ + ++E
Sbjct: 413 ----KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 486 KAVAVDRAKKEAAE----KEQELLKQ--KLQEQQQQMEAQDKS---RKENIAQLKEKLQM 536
+ + K + E ++++LLKQ K+ EQ+++M Q++ ++E + + +EK+Q
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 537 EREHLLREQIMMLEHTQKVQ 556
+ E + +++ + + +K+Q
Sbjct: 529 QEEKMREQEVRLWQQEEKMQ 548
Score = 43.5 bits (101), Expect = 6e-04
Identities = 54/312 (17%), Positives = 130/312 (41%), Gaps = 31/312 (9%)
Query: 291 RLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQ 350
R+GT + ++ ++ N + +E +A +Q + ++ D +
Sbjct: 187 RMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR 246
Query: 351 ELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKL 410
+L ++ + + + K+ K + N+ + L Q +E + + K+
Sbjct: 247 KLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI 306
Query: 411 NELSKGLMES---ISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQ 467
E + + E I + + E +E+I + ++ R+ K +E ++ E +
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
Query: 468 MVI---EESILQSDKALTDREKAVAVDRAK-KEAAEKEQELL----------KQKLQEQQ 513
+ EE I + D+ + ++E+ + K +E EK QE + +K++EQ+
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 514 QQMEAQDKS----------RKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQND----W 559
++M Q++ ++E + +++EK+Q E E + ++ + +K+Q W
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 560 LHEGFKKKYEEM 571
E K+ E++
Sbjct: 487 RQEKLLKQEEKI 498
Score = 38.5 bits (88), Expect = 0.019
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 18/174 (10%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
+ E + +K + + ++ D ++ +E + + K+ EL + + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ------------ 446
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
E +E+ + K + +E QR E EE + +K L EK +
Sbjct: 447 ---EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQL--KEKLQMEREHLLRE 544
EK E ++K+QEQ+++M+ Q++ +E +L +E+ E+E L+E
Sbjct: 504 KMWRQEEKMWEQ-EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 34.3 bits (77), Expect = 0.36
Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 9/113 (7%)
Query: 484 REKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLR 543
REK++A D + +E E L +K + ++ E D E+ Q KE L+ L
Sbjct: 54 REKSIA-DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPD 112
Query: 544 EQIMM---LEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWI 593
++ + + H +K +D + FKK+ E+MN + F++ + K PW+
Sbjct: 113 DEAIEDAGVSHVKK-NSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK----PWL 160
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.8 bits (120), Expect = 4e-06
Identities = 54/283 (19%), Positives = 121/283 (42%), Gaps = 26/283 (9%)
Query: 316 ITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDE 375
+ L + E S + + ++ LP LQ D H E ++++ ++ +E
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKELQSVSAKLQAQV-EE 287
Query: 376 NQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES---ISAGSFSVPGGH 432
N+ + + +N++ + + +E +Q + K+ E + + E I +
Sbjct: 288 NELWNR------LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 433 KLYMETKERI---EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVA 489
++ E +E++ E+ W+ K + +E+ E EE + + ++ + + E+ +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
Query: 490 VDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMML 549
+E EK QE K + QE++Q+ EA+ ++E I + +EK++ + + + R
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR------ 455
Query: 550 EHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPW 592
Q + +HE K + EE E + R + + W
Sbjct: 456 ------QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/200 (17%), Positives = 96/200 (48%), Gaps = 7/200 (3%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
++E ++ ++K E ++ + + +E ++ + K+ E K + +
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE----KIHEQE 464
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
K+ E K + +++ W+ K + +E++++ E EE I + ++ + +E+ +
Sbjct: 465 KIREEEKRQEQEEMWRQEEKIHEQEEIWRQ-KEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHT 552
K E++ ++K++EQ++ ++K ++ +EK Q + + + R++ + E
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 553 QKV--QNDWLHEGFKKKYEE 570
+KV Q + + E +K+ E+
Sbjct: 584 EKVWRQEEKIREQEEKRQEQ 603
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/148 (21%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVI---EESILQSDKALTDREKAVAVDRA 493
E +E+I + +V R+ K +E ++ E + + EE I + ++ + EK ++
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 494 KKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQ 553
+E +EQE + +E+ ++ E + ++E I + +EK Q + E + +++ + E +
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 554 KVQNDWLHEGFKKKYEEMNAEISQFKRM 581
K+Q ++K E +I + + M
Sbjct: 620 KIQEQ------EEKIREQEEKIREQEEM 641
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/136 (20%), Positives = 74/136 (54%), Gaps = 8/136 (5%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E K R +++ W+ K + +++++ E + E+ + + ++ + ++E+ V ++E
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEE--EKRQEQEDKMWRQEEKIREQEEKVW----RQE 590
Query: 497 AAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV- 555
+EQE +Q+ +E+ + E + + ++E I + +EK++ + E + ++ M E +K+
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 556 -QNDWLHEGFKKKYEE 570
Q + + E +K E+
Sbjct: 651 EQEEKMCEQEEKMQEQ 666
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/184 (19%), Positives = 83/184 (45%), Gaps = 27/184 (14%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
K QE +++ E M K+ + + + EE +Q + K+ E + + E
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEK-IQEQEEKIREQEEKIREQ------------ 638
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
E + E+ + K + +E Q E+ EE I + +K + ++E+ +
Sbjct: 639 ---EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI---- 691
Query: 493 AKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHT 552
+EQE + Q+ +E+ + E + ++E + + +EK++ + E + +++ + +
Sbjct: 692 -------REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
Query: 553 QKVQ 556
+K+Q
Sbjct: 745 EKMQ 748
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/148 (20%), Positives = 76/148 (51%), Gaps = 12/148 (8%)
Query: 443 EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAK-----KEA 497
E+ W+ K + +E Q E EE I + ++ + ++E+ + K +
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 498 AEKEQELLKQ--KLQEQQQQMEAQDKS---RKENIAQLKEKLQMEREHLLREQIMMLEHT 552
E+E+++ +Q K+ EQ+++M+ Q+++ ++E I + ++K++ + E + ++ MM E
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Query: 553 QKVQNDWLHEGFKKKYEEMNAEISQFKR 580
+K+ E ++ E+M + + +R
Sbjct: 703 EKMWEQ--EEKMCEQEEKMQEQEEKMRR 728
Score = 40.0 bits (92), Expect = 0.007
Identities = 32/147 (21%), Positives = 70/147 (47%), Gaps = 23/147 (15%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E ++ E+ W+ K + +E Q E EE I + ++ ++E+ +
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG------- 650
Query: 497 AAEKEQELLKQ--KLQEQQQQMEAQD----------KSRKENIAQLKEKLQMEREHLLRE 544
E+E+++ +Q K+QEQ++ M Q+ + ++E I + +E +Q + E + +
Sbjct: 651 --EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708
Query: 545 QIMMLEHTQKVQNDWLHEGFKKKYEEM 571
+ M E +K+Q E +++ E+M
Sbjct: 709 EEKMCEQEEKMQEQ--EEKMRRQEEKM 733
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/66 (25%), Positives = 37/66 (56%)
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT A++++ + ++E + KLQE+ Q +E++ + N+ +LK KL+ +
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 257
Query: 541 LLREQI 546
L ++Q+
Sbjct: 258 LPQQQL 263
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/227 (24%), Positives = 113/227 (49%), Gaps = 27/227 (11%)
Query: 360 EREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLN---ELSKG 416
ER+A+++ + + N+E +KK E + L ++E+S +Q +L E +K
Sbjct: 167 ERDALSLELYRN-TITNEELKKKNAELQEKLR---LAESEKSEIQLNVKELKRKLERAKF 222
Query: 417 LMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQ 476
L+ + + +++ + +E EQ+ +K K +E R E E + +
Sbjct: 223 LLPQVQTNTLQ----EEMWRQEEELREQE-----KKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 477 SDKALTDREKAVAVDRAKKEAAEKEQELLKQK-LQEQQQQMEAQDK---SRKENIAQLKE 532
++ + +EK + +KE E+E+EL +QK L+EQ++QM+ Q++ ++E + + +E
Sbjct: 274 QEEKMRRQEKRLR--EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 533 KLQMEREHLLREQIMMLEHTQKVQND----W-LHEGFKKKYEEMNAE 574
K+ + E L ++ M E QK+++ W E ++K E M +
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/213 (21%), Positives = 97/213 (45%), Gaps = 29/213 (13%)
Query: 369 EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSV 428
E K +E + E M K+ + + + EE Q Q +L E + L E
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ--QQRLPEQKEKLWEQ-------- 445
Query: 429 PGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAV 488
E + E+ W+ K +E++ + E +M +E + + + + ++E+ +
Sbjct: 446 --------EKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKM 495
Query: 489 AVDRAK----KEAAEKEQELLKQK---LQEQQQQMEAQDKSRKENIAQLKEKLQMEREHL 541
K +E ++ E L++K ++EQ++ + ++K R+E Q +EK ++E
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 542 LREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAE 574
+RE+ M E +K++ + E +++ E+M +
Sbjct: 556 MREEERMREREKKMREE--EEMMREQEEKMQEQ 586
Score = 43.9 bits (102), Expect = 5e-04
Identities = 48/231 (20%), Positives = 109/231 (47%), Gaps = 27/231 (11%)
Query: 343 KLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESS 402
++ T+TLQE + RE + K QE + + E M ++ + ++ +E
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE-KMRRQEKR 284
Query: 403 VQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQR 462
++ + +L E K L E K E +E++++ ++ + K +E ++
Sbjct: 285 LREQEKELREQEKELREQ------------KKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 463 FLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQK---LQEQQQQMEAQ 519
EE + + +K + ++E+ + R ++E ++ E L++K ++EQ++ E +
Sbjct: 333 MWRQ----EERLWEQEKQMREQEQKM---RDQEERMWEQDERLREKEERMREQEKMWEQE 385
Query: 520 DKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEE 570
+K ++E + +EK E E +REQ E + Q + + E +K++++
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQ----EEKMQKQEENMWEQEEKEWQQ 432
Score = 43.9 bits (102), Expect = 5e-04
Identities = 32/147 (21%), Positives = 75/147 (51%), Gaps = 11/147 (7%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E + R ++ WQ K + K+ ++ E + +E ++ ++ + +REK + +
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQ--EKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 497 AAEKEQELLKQKLQEQQQQMEAQD---KSRKENIAQLKEKL--QMEREHLLREQIMMLEH 551
E++ + ++K++EQ+++M Q+ + ++E + + +EK+ Q E + + ++ MM E
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 552 TQKVQND----WLHEGFKKKYEEMNAE 574
+K+Q W E ++ EE E
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMRE 664
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/149 (22%), Positives = 79/149 (53%), Gaps = 12/149 (8%)
Query: 443 EQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRA---KKEAAE 499
E+ WQ R + ++++++ E EE I + ++ + D+E+ ++ +++ E
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQ--EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 500 KEQELLKQ--KLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQN 557
+E ++ +Q K+++Q+Q+M Q++ E +L+EK E +REQ M + +K++
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK-----EERMREQKKMWQQEEKMRE 538
Query: 558 DWLHEGFKKKYEEMNAEISQFKRMIDTTK 586
+ + +KK + ++ + +RM + K
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREK 567
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/153 (16%), Positives = 77/153 (50%), Gaps = 4/153 (2%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E K R E+ + +K + +E+ + E EE + + ++ + ++E+ + +++
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM--QEQEEK 610
Query: 497 AAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQ 556
E+E+++ +Q+ +++ Q+ E ++E + + +EK+ + E + ++ M E +K+Q
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 557 NDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDD 589
E +++ E+M + + + + + +
Sbjct: 671 GQ--EEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Score = 40.4 bits (93), Expect = 0.005
Identities = 34/196 (17%), Positives = 95/196 (48%), Gaps = 21/196 (10%)
Query: 380 QKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETK 439
++K E ++ + ++ EE ++ + K+ E + + E K++ + +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ----------EEKMWEQEE 602
Query: 440 ERIEQD--YWQVPRKGVKAKEVFQRFLESQMVIE--ESILQSDKALTDREKAVAVDRAKK 495
+ EQ+ W+ K + +E + + +M+ E E + + ++ + ++E+ + K
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 496 EAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKV 555
E++ + ++K++EQ+++M+ Q++ +E +EK++ + E + ++ M +K+
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMRE----QEEKMRGQEEKMWGQEEKMWGQEEKM 718
Query: 556 QNDWLHEGFKKKYEEM 571
W E ++K E +
Sbjct: 719 ---WGQEEMREKEERI 731
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/214 (19%), Positives = 103/214 (48%), Gaps = 18/214 (8%)
Query: 369 EHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMES---ISAGS 425
E +++ +E +++ E KK L+ +E +Q + K+ E + + E +
Sbjct: 282 EKRLREQEKELREQEKELREQKK----LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Query: 426 FSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIE-ESILQSDKALTDR 484
+ K E ++++ ++ + + +E +R E + + E E +Q ++ + +R
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 485 EKAVAVD----RAKKEAAEKEQELL---KQKLQEQQQQMEAQDKSRKENIAQLKEKLQME 537
EK + + R ++E +K++E + ++K +QQ+ E ++K ++ Q +E+ E
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 538 REHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEM 571
+E +R+Q M +K+ W E +++ ++M
Sbjct: 458 QEEKIRDQEEMWGQEKKM---WRQEKMREQEDQM 488
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/195 (16%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 373 KDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGH 432
K+E QKK + + + Q +E + K+ E E + +
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-----EERMREREKKMREEE 573
Query: 433 KLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDR 492
++ E +E++++ ++ + K E ++ E EE + + ++ + ++E+ +
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMWEQEEKMWEQEEEDKMQE 629
Query: 493 AKKEAAEKEQELLKQ---------KLQEQQQQMEAQDKS---RKENIAQLKEKLQMEREH 540
++ E+E+++ +Q K++EQ+++M Q++ ++E + + +EK+Q + E
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689
Query: 541 LLREQIMMLEHTQKV 555
+ ++ M +K+
Sbjct: 690 MREQEEKMRGQEEKM 704
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/133 (19%), Positives = 62/133 (46%), Gaps = 16/133 (12%)
Query: 437 ETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKE 496
E + R ++ W+ K + + + +R E +M EE ++ + +++ ++ +KE
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIRER--EKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 497 AAEKEQELLKQKLQEQQQQMEAQDK---------SRKENIAQLK-----EKLQMEREHLL 542
++ K+KL EQ++ E ++K ++E Q K EK++ + + +
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 543 REQIMMLEHTQKV 555
++ M + QK+
Sbjct: 490 EQEEKMRDQEQKM 502
Score = 31.2 bits (69), Expect = 3.0
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 481 LTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREH 540
LT A++++ + +E + +LQE+ + E++ + N+ +LK KL+ +
Sbjct: 164 LTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFL 223
Query: 541 LLREQIMMLEHTQKVQNDWLHEGFKK--KYEE 570
L + Q L+ Q + L E KK K EE
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEE 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,640,455
Number of Sequences: 37866
Number of extensions: 1002124
Number of successful extensions: 13111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 735
Number of HSP's that attempted gapping in prelim test: 6697
Number of HSP's gapped (non-prelim): 4071
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.