Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157502199
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
(3565 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 7508 0.0
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 4598 0.0
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 4598 0.0
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 4341 0.0
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 4149 0.0
gi|148886654 polydom [Homo sapiens] 516 e-145
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 358 4e-98
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 354 1e-96
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 320 2e-86
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 317 2e-85
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 258 7e-68
gi|157419154 selectin P precursor [Homo sapiens] 251 7e-66
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 249 3e-65
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 249 3e-65
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 228 8e-59
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 226 4e-58
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 226 4e-58
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 226 4e-58
gi|6912724 tolloid-like 2 [Homo sapiens] 214 1e-54
gi|22547221 tolloid-like 1 [Homo sapiens] 207 1e-52
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 196 5e-49
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 193 3e-48
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 190 2e-47
gi|187960042 selectin E precursor [Homo sapiens] 179 6e-44
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 157 2e-37
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 155 7e-37
gi|4502503 complement component 4 binding protein, alpha chain p... 150 3e-35
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 129 7e-29
gi|62912468 complement component 4 binding protein, beta chain i... 123 4e-27
gi|62912466 complement component 4 binding protein, beta chain i... 123 4e-27
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 7508 bits (19480), Expect = 0.0
Identities = 3565/3565 (100%), Positives = 3565/3565 (100%)
Query: 1 MTAWRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTW 60
MTAWRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTW
Sbjct: 1 MTAWRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTW 60
Query: 61 IIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTL 120
IIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTL
Sbjct: 61 IIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTL 120
Query: 121 WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH 180
WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH
Sbjct: 121 WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH 180
Query: 181 AILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA 240
AILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA
Sbjct: 181 AILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA 240
Query: 241 EPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNH 300
EPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNH
Sbjct: 241 EPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNH 300
Query: 301 RRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRR 360
RRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRR
Sbjct: 301 RRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRR 360
Query: 361 AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS 420
AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS
Sbjct: 361 AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS 420
Query: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS
Sbjct: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
Query: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT
Sbjct: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
Query: 541 GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPN 600
GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPN
Sbjct: 541 GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPN 600
Query: 601 YPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEV 660
YPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEV
Sbjct: 601 YPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEV 660
Query: 661 PSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSV 720
PSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSV
Sbjct: 661 PSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSV 720
Query: 721 SFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYK 780
SFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYK
Sbjct: 721 SFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYK 780
Query: 781 DSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS 840
DSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS
Sbjct: 781 DSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS 840
Query: 841 TGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSC 900
TGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSC
Sbjct: 841 TGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSC 900
Query: 901 DPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWT 960
DPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWT
Sbjct: 901 DPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWT 960
Query: 961 IEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ 1020
IEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ
Sbjct: 961 IEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ 1020
Query: 1021 LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEG 1080
LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEG
Sbjct: 1021 LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEG 1080
Query: 1081 ATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAG 1140
ATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAG
Sbjct: 1081 ATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAG 1140
Query: 1141 KGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGS 1200
KGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGS
Sbjct: 1141 KGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGS 1200
Query: 1201 DTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL 1260
DTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL
Sbjct: 1201 DTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL 1260
Query: 1261 SGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLH 1320
SGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLH
Sbjct: 1261 SGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLH 1320
Query: 1321 FIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGF 1380
FIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGF
Sbjct: 1321 FIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGF 1380
Query: 1381 SIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFF 1440
SIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFF
Sbjct: 1381 SIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFF 1440
Query: 1441 WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNME 1500
WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNME
Sbjct: 1441 WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNME 1500
Query: 1501 PSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
PSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK
Sbjct: 1501 PSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
Query: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP
Sbjct: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
Query: 1621 SCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE 1680
SCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE
Sbjct: 1621 SCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE 1680
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDT 1740
LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDT
Sbjct: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDT 1740
Query: 1741 QCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV 1800
QCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV
Sbjct: 1741 QCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV 1800
Query: 1801 VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH
Sbjct: 1801 VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
Query: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPA 1920
DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPA
Sbjct: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPA 1920
Query: 1921 LPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLS 1980
LPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLS
Sbjct: 1921 LPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLS 1980
Query: 1981 TLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSP 2040
TLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSP
Sbjct: 1981 TLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSP 2040
Query: 2041 MIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI 2100
MIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI
Sbjct: 2041 MIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI 2100
Query: 2101 NSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGTIYS 2160
NSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGTIYS
Sbjct: 2101 NSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGTIYS 2160
Query: 2161 PGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGN 2220
PGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGN
Sbjct: 2161 PGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGN 2220
Query: 2221 TALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIG 2280
TALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIG
Sbjct: 2221 TALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIG 2280
Query: 2281 DFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPG 2340
DFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPG
Sbjct: 2281 DFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPG 2340
Query: 2341 NYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQS 2400
NYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQS
Sbjct: 2341 NYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQS 2400
Query: 2401 NFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFC 2460
NFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFC
Sbjct: 2401 NFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFC 2460
Query: 2461 KPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVY 2520
KPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVY
Sbjct: 2461 KPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVY 2520
Query: 2521 ECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE 2580
ECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE
Sbjct: 2521 ECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE 2580
Query: 2581 YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV 2640
YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV
Sbjct: 2581 YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV 2640
Query: 2641 YGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYR 2700
YGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYR
Sbjct: 2641 YGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYR 2700
Query: 2701 DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDV 2760
DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDV
Sbjct: 2701 DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDV 2760
Query: 2761 VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEY 2820
VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEY
Sbjct: 2761 VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEY 2820
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGA 2880
GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGA
Sbjct: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGA 2880
Query: 2881 VVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
VVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK
Sbjct: 2881 VVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
Query: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSS 3000
SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSS
Sbjct: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSS 3000
Query: 3001 SVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTV 3060
SVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTV
Sbjct: 3001 SVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTV 3060
Query: 3061 SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSI 3120
SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSI
Sbjct: 3061 SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSI 3120
Query: 3121 SYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFF 3180
SYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFF
Sbjct: 3121 SYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFF 3180
Query: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTV 3240
QCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTV
Sbjct: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTV 3240
Query: 3241 FFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLV 3300
FFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLV
Sbjct: 3241 FFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLV 3300
Query: 3301 YTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWK 3360
YTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWK
Sbjct: 3301 YTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWK 3360
Query: 3361 GYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKG 3420
GYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKG
Sbjct: 3361 GYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKG 3420
Query: 3421 QADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDFGKFKLERQDPLNPDQDSSSH 3480
QADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDFGKFKLERQDPLNPDQDSSSH
Sbjct: 3421 QADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDFGKFKLERQDPLNPDQDSSSH 3480
Query: 3481 YHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMY 3540
YHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMY
Sbjct: 3481 YHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMY 3540
Query: 3541 DTNLKPTEAKAVRFDTTLNTVCTVV 3565
DTNLKPTEAKAVRFDTTLNTVCTVV
Sbjct: 3541 DTNLKPTEAKAVRFDTTLNTVCTVV 3565
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 4598 bits (11927), Expect = 0.0
Identities = 2075/3301 (62%), Positives = 2592/3301 (78%), Gaps = 23/3301 (0%)
Query: 285 SSKNWLRLHFTSDSNHRRKGFNAQ------------FQVKKAIELKSRGVKMLPSKDGSH 332
+SK+ L H + RR+ +A+ +VKKAI+ KSRG K+ P KD S+
Sbjct: 370 TSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 429
Query: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
K S+L++GG+ S++CPDPG PENG+R GSDFS +G+ VQFSC+++YVLQG+KSITCQR
Sbjct: 430 KFSILNEGGIKTASNLCPDPGEPENGKRIGSDFS-LGSTVQFSCDEDYVLQGAKSITCQR 488
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIK 452
+ E AAWSDHRP+C+ +TCGSNL+GPSG TSPN+P QY+ NA CVWVIT + +KVI+
Sbjct: 489 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 548
Query: 453 LAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIG 512
+ FEEF+LE GYDTLT+GD G+VGD R+VL VLTGS VPDLIVSMS+QMWLHLQ+D+S+G
Sbjct: 549 INFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVG 608
Query: 513 SPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN 572
S GFK Y+EIEK CGDPG P YG R G F + D L FEC FEL+GE+ I CQ+NN
Sbjct: 609 SVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN 668
Query: 573 QWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDV 632
QWS N P C+F C NFTA G +LSP+YPE YGNN+NC+W IIS+PGSRIHL FNDFD+
Sbjct: 669 QWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDL 728
Query: 633 EPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
E QFDFLAVKD + +LGTF+G EVPS L S+ HI+RLEFQ+DHS +GRGFNITY T
Sbjct: 729 ESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
Query: 693 FGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTV 752
FG NEC DPGIPIN RRFGD F LGSS+S C++GF+KTQG+E+ITCIL DG V+WS +
Sbjct: 789 FGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
Query: 753 PRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDT 812
P+C APCGGH +A SGVIL PGWPGYYKDSL+CEW+IEA+PGHSIKITF+RFQTE+NYD
Sbjct: 849 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 908
Query: 813 LEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESD 872
LEV DGP SPL+G Y+GTQ PQFL S+ NF+YLLFTTDNSRS+ GF IHYESVT+ +
Sbjct: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
Query: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG 932
SCLDPGIPV+G R+G DF I STV+FSCD GY LS +EPL+CE+NH W+H LP+CDALCG
Sbjct: 969 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 1028
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
G ++G SGT+LSPG+P+FYPNSLNCTWT++V+HGKGVQ FHTFHLE HDYLLITE+GS
Sbjct: 1029 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGS 1088
Query: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVP 1052
F++P+ARLTGS LP TI AGL+GNF AQLRFISDFSISYEGFNITFSEY+LEPC+DPG+P
Sbjct: 1089 FTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIP 1148
Query: 1053 AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGN 1112
+ RIGF+FG+GD+LTFSC GYRLEG +++ CLGGGRRVWSAPLPRCVAECGAS N
Sbjct: 1149 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNN 1208
Query: 1113 EGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLG 1172
EG LLSPN+P NY+NNHECIY I+ +AGKGI++ R+F L +GD LK+YDGKD ++ LG
Sbjct: 1209 EGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLG 1268
Query: 1173 TFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRD 1232
FT + GL L+STSN LWLEFN++ TD+GFQL YTSF+L CEDPGIP +GY+I D
Sbjct: 1269 AFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISD 1328
Query: 1233 EGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILS 1292
+GHF + ++Y CNPGY +HGS+ L C++G+RR WD PLPSCIAECGG+ +SGRILS
Sbjct: 1329 QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILS 1388
Query: 1293 PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGS 1352
PGYP PYDNNL C W+IE DPG +SL F+ FDTE +HDIL+VWDGP ++D+LLKE SGS
Sbjct: 1389 PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS 1448
Query: 1353 ALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGD 1412
+PE IHST N +T+QFD+DF+ISKSGF+IQFS+S+A C DPG+P NGTR GD RE GD
Sbjct: 1449 LIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGD 1508
Query: 1413 TVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPY 1472
TV FQCDPGY+LQG+ +ITC+Q+ NR+FWQP PP CIA CGGNLTG +G ILSPN+P PY
Sbjct: 1509 TVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPY 1568
Query: 1473 PPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE 1532
P ++CDW + VN D+VI+L F SF++EP+YDFL+IY+G DSNSPLIGS+Q S+ PERIE
Sbjct: 1569 PHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE 1628
Query: 1533 SSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCD 1592
SS N++ LAFRSD SV +GF +E+K K RE+CFDPGNIMNGTR+G D+KLGST+TY CD
Sbjct: 1629 SSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCD 1688
Query: 1593 SGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQIC 1652
+GY + S++TC++G DG+P W++ LPSC+APCG + TGSEG VLSPNYP NY+ G C
Sbjct: 1689 AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC 1748
Query: 1653 LYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQI 1712
+YSI VPKEFVVFGQF +FQT+L+D+ E++DG Q+ LLSSLSGSHSGE+LPL++ NQI
Sbjct: 1749 VYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI 1808
Query: 1713 LLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGY 1772
+RF++ +A+GFHFVYQAVPRTS TQCSSVPEPR+GRRIG+EF+ GS V F+CNPGY
Sbjct: 1809 TIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGY 1868
Query: 1773 LLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWK 1832
+L GS A+ C++VPN+LAQWND++P+C+VPC G T+R+GTILSPGYPEPY NNLNC+WK
Sbjct: 1869 ILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWK 1928
Query: 1833 IIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLH 1892
I V EG+GIQ+QV+SFATE NWDSL+ +DGGD APRLGS+SGTT+P LLNSTSN LYL+
Sbjct: 1929 ITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLN 1988
Query: 1893 FQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRS 1952
FQSDISV+AAGFHLEY +GL +C EP PS+ IKIGDRYMV DV+SFQC+ GY+LQG S
Sbjct: 1989 FQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 2048
Query: 1953 HISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYG 2012
HI+CMPG VRRWNYP P+C+A CGG +S GVILSPGFPG+YP++LDCTW I+LPIG+G
Sbjct: 2049 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2108
Query: 2013 AHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQN 2072
H+QF+NFSTE HD+LE+++G TS +IG+ SG +P++L STTHET ++F+SD+SQN
Sbjct: 2109 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2168
Query: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGI 2132
+QGF + YQAY+LQ+CPDP PF+NG++I +D++VGQ++SFEC+PGY LIG+ LTC HG+
Sbjct: 2169 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGV 2228
Query: 2133 NRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL 2192
+RNWN+P PRC+A CG N+T+ NGTIYSPG+PDEYP +DC WL+ VPPG+G+YINFT+L
Sbjct: 2229 SRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL 2288
Query: 2193 QTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH 2252
QTE + D+I VWDGPDQNSPQ+G FSGNTALE+ YS++NQ+L+KFHSDF+ GFFVL++H
Sbjct: 2289 QTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYH 2348
Query: 2253 AFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGS 2312
A+QL+ CQPPP VP AE+LTEDD+FEIGD ++YQC PG+TLVG ILTC+L +LQ +G+
Sbjct: 2349 AYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2408
Query: 2313 LPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ 2372
P C+ CPANE+R S+GVILSPGYP +Y N Q C+WSI VE YNIT+FV+ FQ+EK+
Sbjct: 2409 PPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE 2468
Query: 2373 FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPY 2432
FD L+V+DG + QSP+L+ LSG+++ N TS ++++L+WS DH +KKGF+IRY A Y
Sbjct: 2469 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2528
Query: 2433 CSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQ 2492
CS +G I+++T G + S V + C G+R+VG S+A CR++ G + WD+ P CQ
Sbjct: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
A+SCGIP++P NG ++ + ++V Y C++G++L S + TAVCQ DG WSN K P
Sbjct: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
C V CPSI + + EH WR+V+GS EY +V+ SC PGY+ G + C NGTW+
Sbjct: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2708
Query: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGS 2672
+ERP C++ISCG L PPNGNKIGT T YG+TAIFTC+ G+ LVGS VRECL++GLWS S
Sbjct: 2709 NERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2768
Query: 2673 ETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2732
ETRCLAGHCG P+ IVNG + G+ + YRDTVVYQCNPGFRL+G+SVRIC QDH WSGQ P
Sbjct: 2769 ETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLP 2828
Query: 2733 VCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2792
CVP++CGHPG+P +G T+G+ FN NDVV F+CN GYL+QG ++AQC++N QWS P P C
Sbjct: 2829 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2888
Query: 2793 RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSL 2852
+VVNCSDPG N+ R + +F YG + Y C G++L GSS L C NG WD+ L
Sbjct: 2889 KVVNCSDPGIPANSKRESKIEH-GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPL 2947
Query: 2853 PKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPH 2912
P+C+ I CGHPGVP NAVL+GE +T+G+ VHYSC G SL+G +R CQ + HWSG+ PH
Sbjct: 2948 PECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPH 3007
Query: 2913 CTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQP 2972
C+G+ G CGDPGTP HGSR +F+TKS +R++C+ G+ L GS ERTCL NGSW+G QP
Sbjct: 3008 CSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 3067
Query: 2973 VCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPD 3032
C+AV CGNPGT NG + DG FSSSVIY+C EGY SG R CTANGTW+GT P+
Sbjct: 3068 ECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN 3127
Query: 3033 CTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPV 3092
CTIISCGDPG ANG+++G D+ + VSY C PGY ME S CT +G W+ P
Sbjct: 3128 CTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT 3187
Query: 3093 CKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL 3152
C+AV CP PP + NG +EG++F WG SISY C GY+LS A+L+C G G W GE+PQCL
Sbjct: 3188 CRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3247
Query: 3153 PVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDP 3212
P FCGDPGIPA+G+ GKSF Y+SEV F C PFILVGSS R+CQADGTWSG P CI+P
Sbjct: 3248 PKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP 3307
Query: 3213 AHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECI 3272
+C +PG P G QN++ G++VGS V F C+KG+ +QGSTTRTCL +LTWSGIQ ECI
Sbjct: 3308 TQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3367
Query: 3273 PHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
PH+C+QPETPAHA+V +DLP+ GYTL+YTC PGFFLAGG+EHR C++D WTGK P+C+
Sbjct: 3368 PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
Query: 3333 S------KGVREVNETVT-KTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSK 3385
+ K R T + K VP DVF N +WKG Y + G++QP TLTV FNA++ +
Sbjct: 3428 AGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGR 3487
Query: 3386 VNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLE 3445
VNAT S S +EL L+G+YK +EA L+L+ + IK A V K + +NW +DG+VS+ +
Sbjct: 3488 VNATLSN-SNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPD 3546
Query: 3446 RGGFTFQGDIHGKDFGKFKLERQD-PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSG 3504
+ FQG I GKD+G+F L+R ++ +SS+ HGT+S SVA AILVPFFALI +G
Sbjct: 3547 GATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAG 3606
Query: 3505 FAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTV 3564
F FYLYK RT PK QY G + HEN+NGQA+FENPMYDTN K E KAVRFD LNTVCT+
Sbjct: 3607 FGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTM 3666
Query: 3565 V 3565
V
Sbjct: 3667 V 3667
Score = 1680 bits (4350), Expect = 0.0
Identities = 1041/3118 (33%), Positives = 1538/3118 (49%), Gaps = 181/3118 (5%)
Query: 142 SHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
S+ C +PGE G G+ F++G +++SC Y+L+G +TC A+W P
Sbjct: 443 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA-EPGDTIALVFTDFQLEEGYD 260
C+ + CG L+G S + +SP+FP +Y++NA C W I A I + F +F LE GYD
Sbjct: 503 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
Query: 261 FL------EISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKA 314
L E+ LTG +P ++S + + LH +D + GF + K
Sbjct: 562 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 618
Query: 315 IELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQF 374
IE +S C DPG P G R G FS ++F
Sbjct: 619 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDV-LRF 648
Query: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYED 434
C+ + L G KSI CQ + WS + PIC C SN P G + SP+YP Y +
Sbjct: 649 ECQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGN 703
Query: 435 NAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDT--RSVLYVLTGSSVPD 492
N +C+W I +DP I L+F +F+LE +D L V D GD+ +L TG+ VP
Sbjct: 704 NLNCIWTI-ISDPGSRIHLSFNDFDLESQFDFLAVKD----GDSPESPILGTFTGAEVPS 758
Query: 493 LIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTF 552
+ S S+ + L Q+D S+ GF Y C DPGIP +R G +F G +++
Sbjct: 759 HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISV 818
Query: 553 ECPAAF-ELVGERVITC---QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNN 608
C F + G ITC WSG P C C +F+A SG+ILSP +P Y ++
Sbjct: 819 ICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS 878
Query: 609 MNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSG 668
+NC W+I +EPG I + F F E +D L V D +LG+++G +VP L SS
Sbjct: 879 LNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSS 938
Query: 669 HIVRLEFQSDHSTTGRGFNITY--TTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDD 726
+ + L F +D+S + GF I Y T C DPGIP++GRR+G F +GS+VSF CD
Sbjct: 939 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 998
Query: 727 GFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCE 786
G+ + E + C + N WS +P C+A CGG + SG IL PG+P +Y +SL+C
Sbjct: 999 GY-RLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCT 1054
Query: 787 WIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS--TGNF 844
W ++ G ++ F F E ++D L + + + + PL G+ P + + GNF
Sbjct: 1055 WTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNF 1113
Query: 845 -MYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPG 903
L F +D S S GF I + LE C DPGIP G R G +FGI T+TFSC G
Sbjct: 1114 RAQLRFISDFSISYEGFNITFSEYNLE--PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSG 1171
Query: 904 YTLSDDEPLVC--ERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI 961
Y L ++C W+ LP C A CG G +LSP +P Y N+ C ++I
Sbjct: 1172 YRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSI 1231
Query: 962 EVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ- 1020
+V GKG+ + TFHL + D L I + + L G+ +++ + + Q
Sbjct: 1232 QVQAGKGINISARTFHL-AQGDVLKIYDG---KDKTTHLLGAFTGASMRGLTLSSTSNQL 1287
Query: 1021 -LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIG--FHFGVGDSLTFSCFLGYR 1077
L F SD + EGF + ++ ++L C+DPG+P F +I HF G ++ + C GY
Sbjct: 1288 WLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHF-AGSTIIYGCNPGYT 1346
Query: 1078 LEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPSNYDNNHECIYKIE 1136
L G++ L C+ G RR W PLP C+AECG KG + G +LSP +P YDNN C++ IE
Sbjct: 1347 LHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIE 1406
Query: 1137 TEAGKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEF 1195
+ G + L+ +F D L+V+DG + L + L+ ++ST N + ++F
Sbjct: 1407 VDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEIS-GSLIPEGIHSTLNIVTIQF 1465
Query: 1196 NTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSN 1255
+T+ + GF + ++S C DPG+P G R D DTVV + C+PGY + G
Sbjct: 1466 DTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVV-FQCDPGYELQGEE 1524
Query: 1256 TLTCLSGDRR-VWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 1314
+TC+ + R W P CIA CGG + +SG ILSP +P PY ++ C W I +
Sbjct: 1525 RITCIQVENRYFWQPSPPVCIAPCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNAD 1583
Query: 1315 KTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFF 1374
ISL FI F E +D L ++DGP + L+ + S LPE I S+ N++ L F SD
Sbjct: 1584 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1643
Query: 1375 ISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQ 1434
+S +GF +++ + +C DPG NGTR G + G TVT+ CD GY LQG + +TC+
Sbjct: 1644 VSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIM 1703
Query: 1435 LNN-RFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALI 1493
++ R W P+C A CG TG G +LSPNYP+ Y G C + + V +FV+
Sbjct: 1704 GDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1763
Query: 1494 FKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE-SSGNSLFLAFRSDASVGLSG 1552
F F +D + +Y+G S L+ S GS + E + SSGN + + F S + G
Sbjct: 1764 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1822
Query: 1553 FAIEFKEKPREA---CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGA 1609
F ++ PR + C G R+G +F +GS++ + C+ GY + +I C
Sbjct: 1823 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1882
Query: 1610 DGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFA 1669
+ W+ LP+C PCGG T +G +LSP YP Y C++ ITVP+ + Q
Sbjct: 1883 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1942
Query: 1670 YFQTALN-DLAELFDGTHAQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASAR 1725
F T N D + +DG A L GS+SG T+P +TSN + L F + SA
Sbjct: 1943 SFATEHNWDSLDFYDGGDNNAPRL----GSYSGTTIPHLLNSTSNNLYLNFQSDISVSAA 1998
Query: 1726 GFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSV 1785
GFH Y A+ S C P G +IG + G +V F+C+ GY LQG + + C +
Sbjct: 1999 GFHLEYTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC--M 2053
Query: 1786 PNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQV 1845
P + +WN IP C+ C G + G ILSPG+P Y ++L+C W I + G G+ +Q
Sbjct: 2054 PGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQF 2113
Query: 1846 ISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFH 1905
++F+TE D LE+ G T+ +G SG +P+ L ST+++ L+F SD S GFH
Sbjct: 2114 VNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFH 2173
Query: 1906 LEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWN 1965
+ Y+ L +C +P N IG+ + V +SF+C PGYTL G S ++C+ G R WN
Sbjct: 2174 IVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWN 2233
Query: 1966 YPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN 2025
+P P C A CGG ++ + G I SPG+P YPN DC W + +P G G +I F TE
Sbjct: 2234 HPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2293
Query: 2026 HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 2085
+DF+ + +GP SP IGQFSG ++ ST+++ LI F+SD + + F L+Y AY+L
Sbjct: 2294 YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQL 2352
Query: 2086 QNCPDPPPFQNGYMINSD--YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
+ C PPP N ++ D + +G + ++C PG+ L+G+ +LTC+ G + P C
Sbjct: 2353 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2412
Query: 2144 DAPCGYNV--TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYI 2201
C N G I SPG+PD YP L+ C W I+V G+ + + QTE D +
Sbjct: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2472
Query: 2202 AVWDGPDQNSPQLGVFSGN-TALETAYSSTNQVLLKFHSDFSNG-GFFVLNFHAFQLKKC 2259
V+DGP+ SP L SG+ ++ S+ ++V L++ +D N F + + AF C
Sbjct: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2529
Query: 2260 QPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCE 2317
P + P ++++ ++ V++ C G+ LVG C+ SS ++ +P C+
Sbjct: 2530 STPESPPHGYIISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 2318 A-QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVD---TFQSEKQF 2373
A C + T +G IL+ Y + C+ ++ T T+ + +
Sbjct: 2589 AISCGIPKAPT--NGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2646
Query: 2374 DALEVFDGSSGQSPLLV-----VLSGNHTEQSN---FTSRSNQLYLRWSTDHATSKKGFK 2425
V S S +L +++G+H E F+ L ++ +
Sbjct: 2647 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
Query: 2426 IRYAAPYCSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGM 2481
R PYC + P G T + GS + C G+ +VG + C + L
Sbjct: 2707 WRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL-- 2764
Query: 2482 YQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQED 2541
W C A CGIPE NG G + VVY+C+ GF+L S + +CQ+D
Sbjct: 2765 --WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS--SVRICQQD 2820
Query: 2542 GLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLL 2601
WS G+ P+C PV+C + I+ SG+ + V SC+ GY ++G
Sbjct: 2821 HNWS--GQLPSCVPVSCGHPGSP-----IYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKA 2873
Query: 2602 RCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT----VYGATAIFTCNTGYTLVG 2657
+CQAN W+ P C+V++C P N + + YG + CN GY L G
Sbjct: 2874 QCQANRQWS--HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG 2931
Query: 2658 SHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTS 2717
S V C NG W C+ CG P N +SG+ +++ TV Y C L+G S
Sbjct: 2932 SSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQS 2991
Query: 2718 VRICLQDHKWSGQTPVC---VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
R C + WSG P C TCG PG P HG S F V + C+TGY+L G
Sbjct: 2992 SRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGS 3051
Query: 2775 SRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2834
C +NG W+ P C+ V C +PG N G+ + + S++Y C +G+ L
Sbjct: 3052 EERTCLANGSWTGRQPECKAVQCGNPGTTAN----GKVFRIDGTTFSSSVIYSCMEGYIL 3107
Query: 2835 LGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRG--SESL 2892
G S C ANG W +LP C ISCG PG+PAN + G+ + G V Y C+ + L
Sbjct: 3108 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMEL 3167
Query: 2893 IGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQ 2952
G+ R C + WSG +P C C P ++G G +F + + C G++
Sbjct: 3168 NGSRIRTCTINGTWSGVMPTCRAVT---CPTPPQISNGRLEGTNFDWGFSISYICSPGYE 3224
Query: 2953 LRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKT 3012
L TC+ NG+WSG P C CG+PG P G ++ S V ++C +
Sbjct: 3225 LSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK-REGKSFIYQSEVSFSCNFPFIL 3283
Query: 3013 SGLMTRHCTANGTWTGTAPDC---TIISCGDPGTLANGIQFGT-DFTFNKTVSYQCNPGY 3068
G TR C A+GTW+G++P C T SC +PG +G Q T F V + C G+
Sbjct: 3284 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGH 3343
Query: 3069 VMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDF-RWGSSISYSCMDG 3127
+++ T+ T C D W+ +P C C QP + V G D G ++ Y+C G
Sbjct: 3344 LLQGSTTRT--CLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPG 3401
Query: 3128 YQLS-HSAILSCEGRGVWKGEIPQC---LPVFCGDPGIPAEGRLSGKSFTYKSEVFFQ 3181
+ L+ + C W G++P C + DP PA G S K + +VF Q
Sbjct: 3402 FFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPR-PALGTPSPK-LSVPDDVFAQ 3457
Score = 1487 bits (3849), Expect = 0.0
Identities = 998/3079 (32%), Positives = 1480/3079 (48%), Gaps = 216/3079 (7%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
K + CG +QGP+GT SP FP Y + A C W+I N+ IQ++F F LE +D L
Sbjct: 504 KVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTL 563
Query: 87 SVYDGQPQQGNLKVR--LSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
++ DG V L+G +P IVS S + L TD +V + GFK Y+ + +
Sbjct: 564 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 623
Query: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
CG+PG L G+ G F+ D +R+ C G+ L G + C W P C
Sbjct: 624 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPICIF 679
Query: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
C ++ SP +P Y NN +C WTI+++PG I L F DF LE +DFL +
Sbjct: 680 P--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 737
Query: 265 SGTEAPSI----WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
++P TG +PS + S+ + LRL F +D + +GFN +
Sbjct: 738 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN---------- 787
Query: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
+ CPDPGIP N RR G +F ++G+++ CE+ +
Sbjct: 788 ----------------------TFGHNECPDPGIPINARRFGDNF-QLGSSISVICEEGF 824
Query: 381 V-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+ QG+++ITC + + WS P C A CG + PSGVI SP +P Y+D+ +C
Sbjct: 825 IKTQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCE 882
Query: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
WVI +P IK+ FE F+ E YD L V D + +L G+ VP + S SN
Sbjct: 883 WVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNL--LSPLLGSYNGTQVPQFLFSSSN 939
Query: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKG--GCGDPGIPAYGKRTGSSFLHGDTLTFECPAA 557
++L +D+S + GFK Y+ + C DPGIP +G+R G F G T++F C +
Sbjct: 940 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 999
Query: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
+ L E + C++N+ WS P+C C + SG ILSP YPE Y N++NC W +
Sbjct: 1000 YRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV 1059
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIVRLE 674
G + F+ F +E D+L + ++G S L +G+++P + + +L
Sbjct: 1060 THGKGVQFNFHTFHLEDHHDYLLITENG-SFTQPLARLTGSDLPPTINAGLYGNFRAQLR 1118
Query: 675 FQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGS 734
F SD S + GFNIT++ + C DPGIP G R G F +G +++F C G+ + +G+
Sbjct: 1119 FISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGT 1177
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
I C L G VWS+ +PRC A CG T + G++L P +P Y+++ C + I+ + G
Sbjct: 1178 SEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAG 1236
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF-LISTGNFMYLLFTTDN 853
I I+ F D L++ DG ++ L+G + G L ST N ++L F +D
Sbjct: 1237 KGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDT 1295
Query: 854 SRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEP 911
+ GF + Y S E C DPGIP G++ G F ST+ + C+PGYTL
Sbjct: 1296 EGTDEGFQLVYTS--FELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSL 1352
Query: 912 LVCERNHQ--WNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHGKG 968
L C + W++ LPSC A CGG +G+ SG +LSPG+P Y N+L C W IEV G
Sbjct: 1353 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1412
Query: 969 VQMIFHTFHLESSHDYLLITEDGSFSEPVAR-LTGSVLPHTIKAGLFGNFTAQLRFISDF 1027
V + F F E+SHD L + + ++ + + ++GS++P I + L ++F +DF
Sbjct: 1413 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL---NIVTIQFDTDF 1469
Query: 1028 SISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCL 1087
IS GF I FS C DPGVP R G GD++ F C GY L+G ++TC+
Sbjct: 1470 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCI 1529
Query: 1088 G-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 1146
R W P C+A CG ++ G+ G +LSPNFP Y ++ +C + I A I L
Sbjct: 1530 QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1589
Query: 1147 TRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQG 1205
SF + D L +YDG DS+S +G+F ++L I S+SN + L F ++GS + G
Sbjct: 1590 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI-ESSSNTMHLAFRSDGSVSYTG 1648
Query: 1206 FQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD-- 1263
F L Y + C DPG G R+ + TV Y C+ GY + G +TLTC+ GD
Sbjct: 1649 FHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYY-CDAGYVLQGYSTLTCIMGDDG 1707
Query: 1264 RRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIV 1323
R W++ LPSC A CG + + G +LSP YP Y +C + I + F+
Sbjct: 1708 RPGWNRALPSCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVF 1766
Query: 1324 FDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSGFSI 1382
F T + HD+++V+DGP LL SGS E + S+ N +T++F S I+ GF
Sbjct: 1767 FQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHF 1825
Query: 1383 QFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
+ + + C+ P+ G R G+ G +V F C+PGY L G I C + N
Sbjct: 1826 VYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1885
Query: 1440 F-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
W PTCI CGG LT G ILSP YP+PY C W++ V I + SF
Sbjct: 1886 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFA 1945
Query: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
E ++D L Y+G D+N+P +GSY G+ P + S+ N+L+L F+SD SV +GF +E+
Sbjct: 1946 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 2005
Query: 1559 EKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQV 1618
++C +P +G ++G + +G +++QCD GY + S ITC+ G + W+
Sbjct: 2006 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYP 2063
Query: 1619 LPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALND 1677
+P C A CGG + GV+LSP +P NY + C ++I +P F V QF F T ++D
Sbjct: 2064 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2123
Query: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
E+ G+ + ++ LSG +L +T+++ L F + + +GFH VYQA
Sbjct: 2124 YLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY--- 2179
Query: 1738 SDTQCSSVPEPRYGRR---IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Q S P+PR R IG++F+ G + FEC PGY L G++AL C + WN
Sbjct: 2180 ---QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNH 2234
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
+P C C GN T GTI SPGYP+ Y N +C W + V G+GI I TE +
Sbjct: 2235 PLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY 2294
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D + + DG D +P++G FSG T + STSNQ+ + F SD + + F L Y L
Sbjct: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLR 2353
Query: 1915 ACQEPALPSNS--IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
CQ P N+ + D + + D++ +QC PG+TL G + ++C G + + P+C
Sbjct: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
Query: 1973 ATCGGTLSTLG--GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
C L GVILSPG+P SYPN C W IS+ GY + F TE D L+
Sbjct: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2473
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAA--LLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
+ +GP SP++ SG D +A + S HE + + +DH N++GF++ Y A+ +
Sbjct: 2474 VYDGPNIQSPVLISLSG-DYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYC-ST 2531
Query: 2089 PDPPPFQNGYMIN-SDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFPRCD 2144
P+ PP +GY+I+ + + V + C G+ L+G C+ +G + W+ P P C
Sbjct: 2532 PESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHA-WDAPVPACQ 2588
Query: 2145 A-PCGYNVTSQNGTIYSPGF----------PDEYPI-LKDCIWLITVPPG----HGVYIN 2188
A CG NG I + + D Y + K+ + G H
Sbjct: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
Query: 2189 FTLLQTEAVNDYI------AVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2242
++ ++N +I + +G VFS + ++ + L
Sbjct: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL-------P 2701
Query: 2243 NGGFFVLNFHAF-QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTC 2301
NG + N + Q+ C P P + + G + C G+ LVG+ + C
Sbjct: 2702 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVREC 2759
Query: 2302 KLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNIT 2361
LSS L E C E+ +G ++ Y C+ ++ +
Sbjct: 2760 -LSSGLWSESETRCLAGHCGIPELIV--NGQVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2816
Query: 2362 IFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRS-NQLYLRWSTDHATS 2420
D S + + V G G SP+ SGN ++ + S N YL A
Sbjct: 2817 CQQDHNWSGQLPSCVPVSCGHPG-SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC 2875
Query: 2421 KKGFKIRYAAPYCSLTHPLKNGGILNRTAGA--------VGSKVHYFCKPGYRMVGHSNA 2472
+ + + P C + + G N + G+ V Y C PGY + G S
Sbjct: 2876 QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL 2935
Query: 2473 TCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ 2532
C+ N QWD P C + CG P P N +G ++T S V Y C K
Sbjct: 2936 ICQPNG----QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTG--KRSLLG 2989
Query: 2533 QATAVCQEDGLWSNKGKPPTCKPVACPSI-EAQLSEHVIWRLVSGSLNEYG----AQVLL 2587
Q++ CQ +G WS G P C A + + H GS E + V
Sbjct: 2990 QSSRTCQLNGHWS--GSQPHCSGDATGTCGDPGTPGH-------GSRQESNFRTKSTVRY 3040
Query: 2588 SCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATA 2645
+C GY L G C ANG+W +P C+ + CG+ NG K+ + T + ++
Sbjct: 3041 ACDTGYILHGSEERTCLANGSWT--GRQPECKAVQCGNPGTTANG-KVFRIDGTTFSSSV 3097
Query: 2646 IFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVY 2705
I++C GY L G VR+C ANG WSG+ C CG P NG GD + V Y
Sbjct: 3098 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSY 3157
Query: 2706 QCNPGF--RLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNF 2763
C PG+ L G+ +R C + WSG P C +TC P ++G G+ F+ +++
Sbjct: 3158 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISY 3217
Query: 2764 TCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823
C+ GY L + C NG WS +P C C DPG R G +SF Y
Sbjct: 3218 ICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG-----KSFIYQSE 3272
Query: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKCL---AISCGHPGVPANAVLTGEL-FTYG 2879
+ + C F L+GSS C A+G W S P C+ SC +PGVP + F G
Sbjct: 3273 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG 3332
Query: 2880 AVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKT 2939
+VV + C+ L G+ TR C D WSG P C P C P TPAH + +G D +
Sbjct: 3333 SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI---PHSCKQPETPAHANVVGMDLPS 3389
Query: 2940 KS-LLRFSCEMGHQLRGSPE-RTCLLNGSWSGLQPVCEA---VSCGNP----GTPTNGMI 2990
L ++C+ G L G E R C + +W+G P+CEA + +P GTP+ +
Sbjct: 3390 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLS 3449
Query: 2991 VSSDGILFSSSVIYACWEG 3009
V D +F+ + I W+G
Sbjct: 3450 VPDD--VFAQNYI---WKG 3463
Score = 1297 bits (3356), Expect = 0.0
Identities = 908/2900 (31%), Positives = 1325/2900 (45%), Gaps = 244/2900 (8%)
Query: 39 PNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNL 98
P GT+ SP +P GY N NC W II+ +RI LSF+ F LE FD L+V DG + +
Sbjct: 688 PMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPI 747
Query: 99 KVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHG 158
+G ++PS + S IL L F D ++S +GF Y + C +PG + G
Sbjct: 748 LGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFG 807
Query: 159 TRFNIGDKIRYSCLPGYI-LEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSS 217
F +G I C G+I +G +TCI+ G W P C A CGG S
Sbjct: 808 DNFQLGSSISVICEEGFIKTQGTETITCILMDGK-VMWSGLIPKCGA--PCGGHFSAPSG 864
Query: 218 SISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIW---- 273
I SP +P Y+++ +C W I AEPG +I + F FQ E YD LE+ + P++
Sbjct: 865 VILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLL 922
Query: 274 --LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGS 331
G +P + SS N++ L FT+D++ GF ++
Sbjct: 923 GSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYE--------------------- 961
Query: 332 HKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQ 391
V + + C DPGIP +GRR G DFS +G+ V FSC+ Y L + + C
Sbjct: 962 ---------SVTVNTYSCLDPGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLC- 1010
Query: 392 RVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVI 451
E WS P C A CG ++RGPSG I SP YP Y ++ +C W + T K +
Sbjct: 1011 ---EKNHWWSHPLPTCDA-LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH-GKGV 1065
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLI---VSMSNQMWLHLQSD 508
+ F F LE +D L + + G L LTGS +P I + + + L SD
Sbjct: 1066 QFNFHTFHLEDHHDYLLITENGSF---TQPLARLTGSDLPPTINAGLYGNFRAQLRFISD 1122
Query: 509 DSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITC 568
SI GF + E C DPGIP YG R G +F GDTLTF C + + L G I C
Sbjct: 1123 FSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC 1182
Query: 569 QQNNQ--WSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLI 626
+ WS P CV C + T + GI+LSPNYP Y NN C++ I + G I++
Sbjct: 1183 LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINIS 1242
Query: 627 FNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPS-QLASSGHIVRLEFQSDHSTTGRG 685
F + Q D L + D +LG F+G + L+S+ + + LEF SD T G
Sbjct: 1243 ARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEG 1301
Query: 686 FNITYTTFGQNECHDPGIPINGRRFGDR-FLLGSSVSFHCDDGFVKTQGSESITCILQDG 744
F + YT+F + C DPGIP G + D+ GS++ + C+ G+ GS + C+ +
Sbjct: 1302 FQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYT-LHGSSLLKCMTGER 1360
Query: 745 NVVWSSTVPRCEAPCGGHLTA-SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDR 803
W +P C A CGG SSG IL PG+P Y ++L C W+IE PG+ + + F
Sbjct: 1361 R-AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLA 1419
Query: 804 FQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIH 863
F TE ++D L V DGP + L+ E G+ P+ + ST N + + F TD S GF I
Sbjct: 1420 FDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQ 1479
Query: 864 YESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVC---ERNHQW 920
+ S + +C DPG+P+NG R+G TV F CDPGY L +E + C E + W
Sbjct: 1480 FSSSV--ATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFW 1537
Query: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
+ P C A CGG + G SG +LSP FP YP+S +C WTI V+ + + F +F +E
Sbjct: 1538 QPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEP 1597
Query: 981 SHDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
++D+L I + + P + S LP I++ + T L F SD S+SY GF++ +
Sbjct: 1598 NYDFLYIYDGPDSNSPLIGSFQDSKLPERIES---SSNTMHLAFRSDGSVSYTGFHLEYK 1654
Query: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGG--GRRVWSAP 1097
E C DPG R+G + +G ++T+ C GY L+G + LTC+ G GR W+
Sbjct: 1655 AKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRA 1714
Query: 1098 LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT 1157
LP C A CG+ G+EGT+LSPN+P NY H C+Y I + + FQ D
Sbjct: 1715 LPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV 1774
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSF---D 1214
++VYDG S L + + + + S+ N + + F + G T +GF Y +
Sbjct: 1775 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1834
Query: 1215 LVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC--LSGDRRVWDKPLP 1272
+C P +G RI +E + VL+ CNPGY +HGS + C + W+ LP
Sbjct: 1835 STQCSSVPEPRFGRRIGNE-FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLP 1893
Query: 1273 SCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDI 1332
+CI CGG I G ILSPGYP PYDNNL+C W I G I + + F TE D
Sbjct: 1894 TCIVPCGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDS 1952
Query: 1333 LKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATC 1392
L +DG ++ L +SG+ +P ++ST N+L L F SD +S +GF ++++ +C
Sbjct: 1953 LDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC 2012
Query: 1393 NDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAAC 1452
+P P +G + GD GD V+FQCD GY LQG + ITC+ R W P C+A C
Sbjct: 2013 PEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVR-RWNYPIPICLAQC 2071
Query: 1453 GGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGE 1512
GG ++ +GVILSP +P YP +C W + + F + L F +F+ E +D+L + G
Sbjct: 2072 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2131
Query: 1513 DSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIM 1572
S +IG G Q P + S+ + L F SD S GF I ++ ++C DP
Sbjct: 2132 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFR 2191
Query: 1573 NGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTG 1632
NG +G DF +G TI+++C GY ++ S++TC+ G +W+ LP C A CGG T
Sbjct: 2192 NGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRCEALCGGNITA 2249
Query: 1633 SEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALNDLAELFDGTHAQARL 1691
G + SP YP Y Q C + + VP ++ F QT + D ++DG +
Sbjct: 2250 MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQ 2309
Query: 1692 LSSLSGSHSGETLPLATSNQILLRFSA---KSGASARGFHFVYQAVPRTSDTQCSSVPEP 1748
+ SG+ + E++ +TSNQIL++F + SG +H YQ + P P
Sbjct: 2310 IGQFSGNTALESV-YSTSNQILIKFHSDFTTSGFFVLSYH-AYQ-------LRVCQPPPP 2360
Query: 1749 RYGRRI---GSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSG 1805
I EF G I+R++C PG+ L G+ L C+ Q + P C V C
Sbjct: 2361 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRL--GERLQMDGAPPVCQVLCPA 2418
Query: 1806 NFTQ--RRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGG 1863
N + G ILSPGYP+ Y N C W I V +G I + V F TE+ +D L+++DG
Sbjct: 2419 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2478
Query: 1864 DVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALP 1922
++ +P L S SG A + S ++++L + +D GF + Y C P P
Sbjct: 2479 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESP 2535
Query: 1923 SNSIKIGDR-YMVNDVLSFQCEPGYTLQGRSHISCMPGT--VRRWNYPSPLCIA-TCGGT 1978
+ I +N V+ + C+ G+ L G+S C + W+ P P C A +CG
Sbjct: 2536 PHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIP 2595
Query: 1979 LSTLGGVILSPGFPGSYPNNLDCT--WRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPY 2036
+ G IL+ + C +R+S A Q + T +NH+ +
Sbjct: 2596 KAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQ--SDGTWSNHN--KTPRCVV 2651
Query: 2037 HTSPMIGQFSGTDLPAALLSTTH---ETLIHFYSDHSQNRQG-------------FKLAY 2080
T P I F +++ +H +T + F D + G ++
Sbjct: 2652 VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNER 2711
Query: 2081 QAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYP 2139
++ +C + P NG I + S G + F C G++L+G V C G+ W+
Sbjct: 2712 PYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL---WSES 2768
Query: 2140 FPRCDA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN 2198
RC A CG NG + + ++ C PG + + + + N
Sbjct: 2769 ETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQC------NPGFRLIGSSVRICQQDHN 2822
Query: 2199 DYIAVWDGP----------DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFV 2248
W G SP G SGN ++ + V + + G
Sbjct: 2823 -----WSGQLPSCVPVSCGHPGSPIYGRTSGN-----GFNFNDVVTFSCNIGYLMQGPTK 2872
Query: 2249 LNFHAFQLKKCQPP------------PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGT 2296
A + PP PA + E E +F G V Y C+PGY L G+
Sbjct: 2873 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2932
Query: 2297 DILTCKLSSQLQFEGSLPTC------EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSW 2350
+L C+ + Q++ LP C P N V +G Y +C+
Sbjct: 2933 SVLICQPNG--QWDKPLPECIMIDCGHPGVPPNAVLSGEK-------YTFGSTVHYSCTG 2983
Query: 2351 SIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLY 2410
+ + T ++ S Q G+ G ++SNF ++S Y
Sbjct: 2984 KRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKSTVRY 3040
Query: 2411 -------LRWSTDHAT----SKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYF 2459
L S + S G + A C NG + S V Y
Sbjct: 3041 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYS 3100
Query: 2460 CKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVV 2519
C GY + G S C N W P C +SCG P P NG G+++ + V
Sbjct: 3101 CMEGYILSGPSVRQCTANG----TWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS 3156
Query: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
Y C G+ +E + C +G WS G PTC+ V CP+ Q+S + G+
Sbjct: 3157 YMCQPGYTMELNGSRIRTCTINGTWS--GVMPTCRAVTCPT-PPQISN----GRLEGTNF 3209
Query: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT 2639
++G + CSPGY L +L C NGTW+ E P C CG P G + G
Sbjct: 3210 DWGFSISYICSPGYELSFPAVLTCVGNGTWS--GEVPQCLPKFCGDPGIPAQGKREGKSF 3267
Query: 2640 VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL-AGHCGSPDPIVNGHISGD--- 2695
+Y + F+CN + LVGS R C A+G WSGS C+ +P V H S +
Sbjct: 3268 IYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF 3327
Query: 2696 GFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEF 2755
GF V + C G L G++ R CL D WSG P C+P +C P PAH G +
Sbjct: 3328 GFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDL 3387
Query: 2756 NLND-VVNFTCNTGYLLQ-GVSRAQCRSNGQWSSPLPTCRV------------------- 2794
+ + +TC G+ L G CRS+ W+ +P C
Sbjct: 3388 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPK 3447
Query: 2795 VNCSDPGFVENAIRHGQQNF 2814
++ D F +N I G NF
Sbjct: 3448 LSVPDDVFAQNYIWKGSYNF 3467
Score = 414 bits (1065), Expect = e-115
Identities = 187/279 (67%), Positives = 227/279 (81%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
CGG ++G NGTIESPGFP+GYPN ANCTW+II ERNRIQ+ F +FALEE++D LS+YDG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEI 151
P N + RL+GF LP + ST S+ +L T+DFAVSA GFK YE L S +CGNPG
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 144
Query: 152 LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGT 211
KGVL+GTRF++GDKIRYSC+ GYIL+GH LTCI + N ASWDFP P CRAE ACGGT
Sbjct: 145 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 204
Query: 212 LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPS 271
+RG+S ISSP FP+EY NNADCTWTI+AEPGDTI+L+FTDFQ+EE YD+LEI G+E P+
Sbjct: 205 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 264
Query: 272 IWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
IWL+GMN+P P+IS+KNWLRLHF +DSNHR +GF+A +Q
Sbjct: 265 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 184 bits (467), Expect = 1e-45
Identities = 112/319 (35%), Positives = 159/319 (49%), Gaps = 45/319 (14%)
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI-SG 266
CGGTL+G + +I SP FP Y N A+CTW I+AE + I +VF F LEE YD+L + G
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 267 TEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVK 323
P+ + LTG +LP PV S+K+ L TSD GF ++
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 131
Query: 324 MLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQ 383
L S C +PG+P G G+ F VG +++SC Y+L
Sbjct: 132 -------------------ELQSSSCGNPGVPPKGVLYGTRFD-VGDKIRYSCVTGYILD 171
Query: 384 GSKSITCQRVTETLAAWSDHRPICRAR-TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVI 442
G +TC + A+W PICRA CG +RG SG+I+SP++P +Y +NA C W I
Sbjct: 172 GHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI 231
Query: 443 TTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMW 502
+P I L F +F++E YD L + G ++ L+G ++P I+S N +
Sbjct: 232 -VAEPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLR 284
Query: 503 LHLQSDDSIGSPGFKAVYQ 521
LH +D + GF A YQ
Sbjct: 285 LHFVTDSNHRYRGFSAPYQ 303
Score = 182 bits (461), Expect = 7e-45
Identities = 98/291 (33%), Positives = 145/291 (49%), Gaps = 8/291 (2%)
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
T + C G GTI SPG+P Y N NC W II E + IQI SFA E+ +
Sbjct: 17 TASGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEY 76
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D L ++DG +G +P + ST + L SD +V+A GF + Y+ + +
Sbjct: 77 DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSS 136
Query: 1915 ACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVR--RWNYPSPLCI 1972
+C P +P + G R+ V D + + C GY L G ++C+ +V W++P P+C
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Query: 1973 A--TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
A CGGT+ G+I SP FP Y NN DCTW I G + F +F E +D+LE
Sbjct: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 256
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQ 2081
I+ + P SG ++P ++S + +HF +D + +GF YQ
Sbjct: 257 IEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 177 bits (448), Expect = 2e-43
Identities = 100/286 (34%), Positives = 152/286 (53%), Gaps = 13/286 (4%)
Query: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVG 470
TCG L+G +G I SP +P Y + A+C WVI + ++ I++ F+ F LE YD L++
Sbjct: 24 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLY 82
Query: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
D + LTG +P + S + L L SD ++ + GFK Y+E++ CG+
Sbjct: 83 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
Query: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN----QWSGNKPSC--VFS 584
PG+P G G+ F GD + + C + L G +TC N+ W P C +
Sbjct: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
Query: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
C SSGII SP++P EY NN +C W I++EPG I LIF DF +E ++D+L + +
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--E 258
Query: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
G T+ SG +P + S+ + +RL F +D + RGF+ Y
Sbjct: 259 GSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 169 bits (428), Expect = 5e-41
Identities = 98/287 (34%), Positives = 144/287 (50%), Gaps = 8/287 (2%)
Query: 1275 IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILK 1334
I CGG + +G I SPG+P Y N +CTW+I A+ I + F F E +D L
Sbjct: 22 IYTCGGTLKGL-NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 80
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCND 1394
++DG +G LP + ST + +L+ SDF +S GF + + +++C +
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
Query: 1395 PGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTCIA--A 1451
PG+P G YG + GD + + C GY L G ++TC+ + N W P C A A
Sbjct: 141 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
CGG + G +G+I SP++P Y +C W + P I+LIF F ME YD+L I
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--- 257
Query: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
E S P I G P I S+ N L L F +D++ GF+ ++
Sbjct: 258 EGSEPPTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 167 bits (424), Expect = 1e-40
Identities = 91/287 (31%), Positives = 140/287 (48%), Gaps = 8/287 (2%)
Query: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
+++C +G I SP +P Y N NC W+II+E +RI ++F F +E ++D+L++
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
D +G +P + S+ + L SD + + GF + Y + C +P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV-WSSTVPRCEA--P 758
G+P G +G RF +G + + C G++ G +TCI N W VP C A
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
CGG + SSG+I P +P Y ++ C W I A+PG +I + F FQ E YD LE+
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE-- 258
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE 865
S P G P +IS N++ L F TD++ GF Y+
Sbjct: 259 --GSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 166 bits (421), Expect = 3e-40
Identities = 101/288 (35%), Positives = 143/288 (49%), Gaps = 18/288 (6%)
Query: 931 CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITED 990
CGG ++G +GT+ SPGFP YPN NCTW I +Q++F +F LE +DYL + +
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD- 83
Query: 991 GSFSEPV---ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCD 1047
P RLTG LP + + LR SDF++S GF + + E C
Sbjct: 84 -GHPHPTNFRTRLTGFHLPPPVTS---TKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Query: 1048 DPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRV--WSAPLPRCVAE- 1104
+PGVP G F VGD + +SC GY L+G +LTC+ W P+P C AE
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Query: 1105 -CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYD 1162
CG +++G+ G + SP+FP+ Y NN +C + I E G I L FQ+ E D L++
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI-- 257
Query: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
S P + + + S N L L F T+ + +GF Y
Sbjct: 258 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 159 bits (403), Expect = 4e-38
Identities = 93/273 (34%), Positives = 134/273 (49%), Gaps = 8/273 (2%)
Query: 1972 IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
I TCGGTL L G I SPGFP YPN +CTW I I F +F+ E +D+L +
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+G H + + +G LP + ST + SD + + GFK+ Y+ + +C +P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC-QHGIN-RNWNYPFPRCDA--PC 2147
G + + + VG + + C GYIL GHP LTC + +N +W++P P C A C
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
Query: 2148 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGP 2207
G + +G I SP FP+EY DC W I PG + + FT Q E DY+ +
Sbjct: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI---- 257
Query: 2208 DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
+ + P SG S+ N + L F +D
Sbjct: 258 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTD 290
Score = 159 bits (403), Expect = 4e-38
Identities = 97/286 (33%), Positives = 143/286 (50%), Gaps = 14/286 (4%)
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
CGG L +G I PG+P Y + +C W+I A+ + I+I F F E YD L + DG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
+ G P + ST + L T+D + S+ GF ++YE L+S SC +PG
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEE--LQSSSCGNPG 142
Query: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNH----QWNHALPSCDA--LCG 932
+P G +G F + + +SC GY L L C N W+ +P C A CG
Sbjct: 143 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
G ++G SG + SP FP+ Y N+ +CTWTI G + +IF F +E +DYL I +GS
Sbjct: 203 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--EGS 260
Query: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
P L+G +P I + +L F++D + Y GF+ +
Sbjct: 261 -EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 138 bits (348), Expect = 9e-32
Identities = 105/296 (35%), Positives = 138/296 (46%), Gaps = 20/296 (6%)
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYDG 1163
CG ++KG GT+ SP FP Y N C + I E I + +SF L E D L +YDG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 1164 KDSSSRPLGTFTKNELLGLIL----NSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
P T + L G L ST + L ++ + + GF++ Y C
Sbjct: 85 -----HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Query: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL--SGDRRVWDKPLPSCIAE 1277
+PG+P G D + YSC GY + G LTC+ S + WD P+P C AE
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKI-RYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 1278 --CGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKV 1335
CGG + +SG I SP +P Y NN CTW I A+PG TISL F F E +D L++
Sbjct: 199 DACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 257
Query: 1336 WDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
+G I L SG +P I S N L L F +D GFS + S T
Sbjct: 258 -EGSEPPTIWL---SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
Score = 137 bits (345), Expect = 2e-31
Identities = 86/289 (29%), Positives = 129/289 (44%), Gaps = 12/289 (4%)
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
I CGG L G G I SP +P YP G C W + I ++F+SF +E YD+L +
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81
Query: 1509 YEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP 1568
Y+G + G P + S+ + L SD +V GF + ++E +C +P
Sbjct: 82 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 141
Query: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA--PC 1626
G G GT F +G I Y C +GY + +TC+ + SWD +P C A C
Sbjct: 142 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 201
Query: 1627 GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTH 1686
GG GS G++ SP++P+ Y C ++I + F FQ + E +D
Sbjct: 202 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQ-----MEEKYDYLE 256
Query: 1687 AQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQ 1732
+ ++ SG +P ++ N + L F S RGF YQ
Sbjct: 257 IEGSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 132 bits (333), Expect = 5e-30
Identities = 98/316 (31%), Positives = 142/316 (44%), Gaps = 22/316 (6%)
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
CG + NGTI SPGFP YP +C W+I + + I F E DY++++DG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 2207 ---PDQNSPQLGVFSGNTALETAYSSTNQVL-LKFHSDFSNGGF-FVLNFHAFQLKKCQP 2261
P +L F L +ST V L+ SDF+ F + + Q C
Sbjct: 85 HPHPTNFRTRLTGFH----LPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
Query: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCEAQ 2319
P P+ + F++GD ++Y C GY L G LTC +S ++ +P C A+
Sbjct: 141 PGVPPKGVLY--GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 2320 CPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVF 2379
GSSG+I SP +P Y N+ C+W+I EP I++ FQ E+++D LE+
Sbjct: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
Query: 2380 DGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPL 2439
G P + LSG + S N L L + TD +GF Y +LTH
Sbjct: 258 ---EGSEPPTIWLSGMNIPPP-IISNKNWLRLHFVTDSNHRYRGFSAPYQGS-STLTHTT 312
Query: 2440 KNGGILNR---TAGAV 2452
G + T GA+
Sbjct: 313 STGELEEHNRTTTGAI 328
Score = 125 bits (314), Expect = 7e-28
Identities = 85/289 (29%), Positives = 124/289 (42%), Gaps = 15/289 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEF---VVFGQFAYFQTALNDLAELF 1682
CGG G G + SP +P+ Y G C + I + +VF FA + D L+
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEY--DYLSLY 82
Query: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQC 1742
DG + L+G H + +T + LR ++ SA GF Y+ + +S C
Sbjct: 83 DGHPHPTNFRTRLTGFHLPPPVT-STKSVFSLRLTSDFAVSAHGFKVYYEELQSSS---C 138
Query: 1743 SSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVV- 1801
+ P G G+ F G +R+ C GY+L G L C + A W+ +P C
Sbjct: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 1802 -PCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
C G G I SP +P Y NN +C W I+ G I + F E+ +D LEI
Sbjct: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 257
Query: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK 1909
+ + P SG +P + S N L LHF +D + GF Y+
Sbjct: 258 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 93.6 bits (231), Expect = 3e-18
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSP 2387
G +G I SPG+P Y N C+W I E I I +F E+++D L ++DG +
Sbjct: 31 GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTN 90
Query: 2388 LLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA-PYCSLTHP-LKNGGIL 2445
L+G H TS + LR ++D A S GFK+ Y S +P + G+L
Sbjct: 91 FRTRLTGFHLPPP-VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVL 149
Query: 2446 NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCG 2497
T VG K+ Y C GY + GH TC N + WD P+C+A +CG
Sbjct: 150 YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 202
Score = 53.1 bits (126), Expect = 5e-06
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 2738 TCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSN----GQWSSPLPTCR 2793
+CG+PG P G G+ F++ D + ++C TGY+L G + C +N W P+P CR
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Score = 52.4 bits (124), Expect = 8e-06
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN----GSWSGLQPVCEA 2976
CG+PG P G G F +R+SC G+ L G P+ TC+ N SW P+C A
Sbjct: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
Query: 2977 V-SCGNPGTPTNGMIVS 2992
+CG ++G+I S
Sbjct: 198 EDACGGTMRGSSGIISS 214
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 3037 SCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSAT--IRCTKDGRWNPSKPVCK 3094
SCG+PG G+ +GT F + Y C GY+++ T W+ P+C+
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Query: 3095 A 3095
A
Sbjct: 197 A 197
Score = 40.4 bits (93), Expect = 0.032
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 2796 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGL----WDRS 2851
+C +PG + +G + F+ G I Y C G+ L G LTC+AN + WD
Sbjct: 137 SCGNPGVPPKGVLYGTR-----FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 191
Query: 2852 LPKCLA-ISCG 2861
+P C A +CG
Sbjct: 192 VPICRAEDACG 202
Score = 40.0 bits (92), Expect = 0.041
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 2859 SCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDS----HWSGALPHCT 2914
SCG+PGVP VL G F G + YSC L G+ C +S W +P C
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Query: 2915 GNNPGFCG 2922
+ CG
Sbjct: 197 AEDA--CG 202
Score = 37.7 bits (86), Expect = 0.21
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 3156 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD----GTWSGIQPTC 3209
CG+PG+P +G L G F ++ + C + +IL G + C A+ +W P C
Sbjct: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
Score = 37.0 bits (84), Expect = 0.35
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 3215 NTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLAN 3261
++C +PG P G+ +R ++VG + + C GY + G TC+AN
Sbjct: 136 SSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIAN 181
Score = 36.2 bits (82), Expect = 0.60
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 2622 SCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCL 2677
SCG+ PP G GT G ++C TGY L G C+AN + W C
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Query: 2678 A-GHCGSPDPIVNGHISGDGF 2697
A CG +G IS F
Sbjct: 197 AEDACGGTMRGSSGIISSPSF 217
Score = 35.8 bits (81), Expect = 0.78
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGV----WKGEIPQC-L 3152
C P G + G+ F G I YSC+ GY L L+C V W +P C
Sbjct: 138 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
Query: 3153 PVFCGDPGIPAEGRLSGKSF 3172
CG + G +S SF
Sbjct: 198 EDACGGTMRGSSGIISSPSF 217
Score = 34.3 bits (77), Expect = 2.3
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 6/79 (7%)
Query: 2975 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN----GTWTGTA 3030
++ SCGNPG P G++ + + Y+C GY G C AN +W
Sbjct: 134 QSSSCGNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 192
Query: 3031 PDCTI-ISCGDPGTLANGI 3048
P C +CG ++GI
Sbjct: 193 PICRAEDACGGTMRGSSGI 211
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 4598 bits (11927), Expect = 0.0
Identities = 2075/3301 (62%), Positives = 2592/3301 (78%), Gaps = 23/3301 (0%)
Query: 285 SSKNWLRLHFTSDSNHRRKGFNAQ------------FQVKKAIELKSRGVKMLPSKDGSH 332
+SK+ L H + RR+ +A+ +VKKAI+ KSRG K+ P KD S+
Sbjct: 410 TSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSN 469
Query: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
K S+L++GG+ S++CPDPG PENG+R GSDFS +G+ VQFSC+++YVLQG+KSITCQR
Sbjct: 470 KFSILNEGGIKTASNLCPDPGEPENGKRIGSDFS-LGSTVQFSCDEDYVLQGAKSITCQR 528
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIK 452
+ E AAWSDHRP+C+ +TCGSNL+GPSG TSPN+P QY+ NA CVWVIT + +KVI+
Sbjct: 529 IAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQ 588
Query: 453 LAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIG 512
+ FEEF+LE GYDTLT+GD G+VGD R+VL VLTGS VPDLIVSMS+QMWLHLQ+D+S+G
Sbjct: 589 INFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVG 648
Query: 513 SPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN 572
S GFK Y+EIEK CGDPG P YG R G F + D L FEC FEL+GE+ I CQ+NN
Sbjct: 649 SVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENN 708
Query: 573 QWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDV 632
QWS N P C+F C NFTA G +LSP+YPE YGNN+NC+W IIS+PGSRIHL FNDFD+
Sbjct: 709 QWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDL 768
Query: 633 EPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
E QFDFLAVKD + +LGTF+G EVPS L S+ HI+RLEFQ+DHS +GRGFNITY T
Sbjct: 769 ESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 828
Query: 693 FGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTV 752
FG NEC DPGIPIN RRFGD F LGSS+S C++GF+KTQG+E+ITCIL DG V+WS +
Sbjct: 829 FGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 888
Query: 753 PRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDT 812
P+C APCGGH +A SGVIL PGWPGYYKDSL+CEW+IEA+PGHSIKITF+RFQTE+NYD
Sbjct: 889 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 948
Query: 813 LEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESD 872
LEV DGP SPL+G Y+GTQ PQFL S+ NF+YLLFTTDNSRS+ GF IHYESVT+ +
Sbjct: 949 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 1008
Query: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG 932
SCLDPGIPV+G R+G DF I STV+FSCD GY LS +EPL+CE+NH W+H LP+CDALCG
Sbjct: 1009 SCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG 1068
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
G ++G SGT+LSPG+P+FYPNSLNCTWT++V+HGKGVQ FHTFHLE HDYLLITE+GS
Sbjct: 1069 GDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGS 1128
Query: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVP 1052
F++P+ARLTGS LP TI AGL+GNF AQLRFISDFSISYEGFNITFSEY+LEPC+DPG+P
Sbjct: 1129 FTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIP 1188
Query: 1053 AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGN 1112
+ RIGF+FG+GD+LTFSC GYRLEG +++ CLGGGRRVWSAPLPRCVAECGAS N
Sbjct: 1189 QYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNN 1248
Query: 1113 EGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLG 1172
EG LLSPN+P NY+NNHECIY I+ +AGKGI++ R+F L +GD LK+YDGKD ++ LG
Sbjct: 1249 EGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLG 1308
Query: 1173 TFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRD 1232
FT + GL L+STSN LWLEFN++ TD+GFQL YTSF+L CEDPGIP +GY+I D
Sbjct: 1309 AFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISD 1368
Query: 1233 EGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILS 1292
+GHF + ++Y CNPGY +HGS+ L C++G+RR WD PLPSCIAECGG+ +SGRILS
Sbjct: 1369 QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILS 1428
Query: 1293 PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGS 1352
PGYP PYDNNL C W+IE DPG +SL F+ FDTE +HDIL+VWDGP ++D+LLKE SGS
Sbjct: 1429 PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGS 1488
Query: 1353 ALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGD 1412
+PE IHST N +T+QFD+DF+ISKSGF+IQFS+S+A C DPG+P NGTR GD RE GD
Sbjct: 1489 LIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGD 1548
Query: 1413 TVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPY 1472
TV FQCDPGY+LQG+ +ITC+Q+ NR+FWQP PP CIA CGGNLTG +G ILSPN+P PY
Sbjct: 1549 TVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPY 1608
Query: 1473 PPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE 1532
P ++CDW + VN D+VI+L F SF++EP+YDFL+IY+G DSNSPLIGS+Q S+ PERIE
Sbjct: 1609 PHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIE 1668
Query: 1533 SSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCD 1592
SS N++ LAFRSD SV +GF +E+K K RE+CFDPGNIMNGTR+G D+KLGST+TY CD
Sbjct: 1669 SSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCD 1728
Query: 1593 SGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQIC 1652
+GY + S++TC++G DG+P W++ LPSC+APCG + TGSEG VLSPNYP NY+ G C
Sbjct: 1729 AGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNC 1788
Query: 1653 LYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQI 1712
+YSI VPKEFVVFGQF +FQT+L+D+ E++DG Q+ LLSSLSGSHSGE+LPL++ NQI
Sbjct: 1789 VYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI 1848
Query: 1713 LLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGY 1772
+RF++ +A+GFHFVYQAVPRTS TQCSSVPEPR+GRRIG+EF+ GS V F+CNPGY
Sbjct: 1849 TIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGY 1908
Query: 1773 LLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWK 1832
+L GS A+ C++VPN+LAQWND++P+C+VPC G T+R+GTILSPGYPEPY NNLNC+WK
Sbjct: 1909 ILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWK 1968
Query: 1833 IIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLH 1892
I V EG+GIQ+QV+SFATE NWDSL+ +DGGD APRLGS+SGTT+P LLNSTSN LYL+
Sbjct: 1969 ITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLN 2028
Query: 1893 FQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRS 1952
FQSDISV+AAGFHLEY +GL +C EP PS+ IKIGDRYMV DV+SFQC+ GY+LQG S
Sbjct: 2029 FQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHS 2088
Query: 1953 HISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYG 2012
HI+CMPG VRRWNYP P+C+A CGG +S GVILSPGFPG+YP++LDCTW I+LPIG+G
Sbjct: 2089 HITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFG 2148
Query: 2013 AHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQN 2072
H+QF+NFSTE HD+LE+++G TS +IG+ SG +P++L STTHET ++F+SD+SQN
Sbjct: 2149 VHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQN 2208
Query: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGI 2132
+QGF + YQAY+LQ+CPDP PF+NG++I +D++VGQ++SFEC+PGY LIG+ LTC HG+
Sbjct: 2209 KQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGV 2268
Query: 2133 NRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL 2192
+RNWN+P PRC+A CG N+T+ NGTIYSPG+PDEYP +DC WL+ VPPG+G+YINFT+L
Sbjct: 2269 SRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVL 2328
Query: 2193 QTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH 2252
QTE + D+I VWDGPDQNSPQ+G FSGNTALE+ YS++NQ+L+KFHSDF+ GFFVL++H
Sbjct: 2329 QTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYH 2388
Query: 2253 AFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGS 2312
A+QL+ CQPPP VP AE+LTEDD+FEIGD ++YQC PG+TLVG ILTC+L +LQ +G+
Sbjct: 2389 AYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGA 2448
Query: 2313 LPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ 2372
P C+ CPANE+R S+GVILSPGYP +Y N Q C+WSI VE YNIT+FV+ FQ+EK+
Sbjct: 2449 PPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE 2508
Query: 2373 FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPY 2432
FD L+V+DG + QSP+L+ LSG+++ N TS ++++L+WS DH +KKGF+IRY A Y
Sbjct: 2509 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2568
Query: 2433 CSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQ 2492
CS +G I+++T G + S V + C G+R+VG S+A CR++ G + WD+ P CQ
Sbjct: 2569 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
A+SCGIP++P NG ++ + ++V Y C++G++L S + TAVCQ DG WSN K P
Sbjct: 2629 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2688
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
C V CPSI + + EH WR+V+GS EY +V+ SC PGY+ G + C NGTW+
Sbjct: 2689 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2748
Query: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGS 2672
+ERP C++ISCG L PPNGNKIGT T YG+TAIFTC+ G+ LVGS VRECL++GLWS S
Sbjct: 2749 NERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSES 2808
Query: 2673 ETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2732
ETRCLAGHCG P+ IVNG + G+ + YRDTVVYQCNPGFRL+G+SVRIC QDH WSGQ P
Sbjct: 2809 ETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLP 2868
Query: 2733 VCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2792
CVP++CGHPG+P +G T+G+ FN NDVV F+CN GYL+QG ++AQC++N QWS P P C
Sbjct: 2869 SCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC 2928
Query: 2793 RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSL 2852
+VVNCSDPG N+ R + +F YG + Y C G++L GSS L C NG WD+ L
Sbjct: 2929 KVVNCSDPGIPANSKRESKIEH-GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPL 2987
Query: 2853 PKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPH 2912
P+C+ I CGHPGVP NAVL+GE +T+G+ VHYSC G SL+G +R CQ + HWSG+ PH
Sbjct: 2988 PECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPH 3047
Query: 2913 CTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQP 2972
C+G+ G CGDPGTP HGSR +F+TKS +R++C+ G+ L GS ERTCL NGSW+G QP
Sbjct: 3048 CSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 3107
Query: 2973 VCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPD 3032
C+AV CGNPGT NG + DG FSSSVIY+C EGY SG R CTANGTW+GT P+
Sbjct: 3108 ECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPN 3167
Query: 3033 CTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPV 3092
CTIISCGDPG ANG+++G D+ + VSY C PGY ME S CT +G W+ P
Sbjct: 3168 CTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPT 3227
Query: 3093 CKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL 3152
C+AV CP PP + NG +EG++F WG SISY C GY+LS A+L+C G G W GE+PQCL
Sbjct: 3228 CRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3287
Query: 3153 PVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDP 3212
P FCGDPGIPA+G+ GKSF Y+SEV F C PFILVGSS R+CQADGTWSG P CI+P
Sbjct: 3288 PKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP 3347
Query: 3213 AHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECI 3272
+C +PG P G QN++ G++VGS V F C+KG+ +QGSTTRTCL +LTWSGIQ ECI
Sbjct: 3348 TQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3407
Query: 3273 PHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
PH+C+QPETPAHA+V +DLP+ GYTL+YTC PGFFLAGG+EHR C++D WTGK P+C+
Sbjct: 3408 PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICE 3467
Query: 3333 S------KGVREVNETVT-KTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSK 3385
+ K R T + K VP DVF N +WKG Y + G++QP TLTV FNA++ +
Sbjct: 3468 AGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGR 3527
Query: 3386 VNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLE 3445
VNAT S S +EL L+G+YK +EA L+L+ + IK A V K + +NW +DG+VS+ +
Sbjct: 3528 VNATLSN-SNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPD 3586
Query: 3446 RGGFTFQGDIHGKDFGKFKLERQD-PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSG 3504
+ FQG I GKD+G+F L+R ++ +SS+ HGT+S SVA AILVPFFALI +G
Sbjct: 3587 GATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAG 3646
Query: 3505 FAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTV 3564
F FYLYK RT PK QY G + HEN+NGQA+FENPMYDTN K E KAVRFD LNTVCT+
Sbjct: 3647 FGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTM 3706
Query: 3565 V 3565
V
Sbjct: 3707 V 3707
Score = 1680 bits (4350), Expect = 0.0
Identities = 1041/3118 (33%), Positives = 1538/3118 (49%), Gaps = 181/3118 (5%)
Query: 142 SHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
S+ C +PGE G G+ F++G +++SC Y+L+G +TC A+W P
Sbjct: 483 SNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 542
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA-EPGDTIALVFTDFQLEEGYD 260
C+ + CG L+G S + +SP+FP +Y++NA C W I A I + F +F LE GYD
Sbjct: 543 CKVK-TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 601
Query: 261 FL------EISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKA 314
L E+ LTG +P ++S + + LH +D + GF + K
Sbjct: 602 TLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY---KE 658
Query: 315 IELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQF 374
IE +S C DPG P G R G FS ++F
Sbjct: 659 IEKES-----------------------------CGDPGTPLYGIREGDGFSNRDV-LRF 688
Query: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYED 434
C+ + L G KSI CQ + WS + PIC C SN P G + SP+YP Y +
Sbjct: 689 ECQFGFELIGEKSIVCQENNQ----WSANIPIC-IFPCLSNFTAPMGTVLSPDYPEGYGN 743
Query: 435 NAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDT--RSVLYVLTGSSVPD 492
N +C+W I +DP I L+F +F+LE +D L V D GD+ +L TG+ VP
Sbjct: 744 NLNCIWTI-ISDPGSRIHLSFNDFDLESQFDFLAVKD----GDSPESPILGTFTGAEVPS 798
Query: 493 LIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTF 552
+ S S+ + L Q+D S+ GF Y C DPGIP +R G +F G +++
Sbjct: 799 HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISV 858
Query: 553 ECPAAF-ELVGERVITC---QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNN 608
C F + G ITC WSG P C C +F+A SG+ILSP +P Y ++
Sbjct: 859 ICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS 918
Query: 609 MNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSG 668
+NC W+I +EPG I + F F E +D L V D +LG+++G +VP L SS
Sbjct: 919 LNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSS 978
Query: 669 HIVRLEFQSDHSTTGRGFNITY--TTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDD 726
+ + L F +D+S + GF I Y T C DPGIP++GRR+G F +GS+VSF CD
Sbjct: 979 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 1038
Query: 727 GFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCE 786
G+ + E + C + N WS +P C+A CGG + SG IL PG+P +Y +SL+C
Sbjct: 1039 GY-RLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCT 1094
Query: 787 WIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIS--TGNF 844
W ++ G ++ F F E ++D L + + + + PL G+ P + + GNF
Sbjct: 1095 WTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNF 1153
Query: 845 -MYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPG 903
L F +D S S GF I + LE C DPGIP G R G +FGI T+TFSC G
Sbjct: 1154 RAQLRFISDFSISYEGFNITFSEYNLE--PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSG 1211
Query: 904 YTLSDDEPLVC--ERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI 961
Y L ++C W+ LP C A CG G +LSP +P Y N+ C ++I
Sbjct: 1212 YRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSI 1271
Query: 962 EVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQ- 1020
+V GKG+ + TFHL + D L I + + L G+ +++ + + Q
Sbjct: 1272 QVQAGKGINISARTFHL-AQGDVLKIYDG---KDKTTHLLGAFTGASMRGLTLSSTSNQL 1327
Query: 1021 -LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIG--FHFGVGDSLTFSCFLGYR 1077
L F SD + EGF + ++ ++L C+DPG+P F +I HF G ++ + C GY
Sbjct: 1328 WLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHF-AGSTIIYGCNPGYT 1386
Query: 1078 LEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPSNYDNNHECIYKIE 1136
L G++ L C+ G RR W PLP C+AECG KG + G +LSP +P YDNN C++ IE
Sbjct: 1387 LHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIE 1446
Query: 1137 TEAGKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEF 1195
+ G + L+ +F D L+V+DG + L + L+ ++ST N + ++F
Sbjct: 1447 VDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEIS-GSLIPEGIHSTLNIVTIQF 1505
Query: 1196 NTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSN 1255
+T+ + GF + ++S C DPG+P G R D DTVV + C+PGY + G
Sbjct: 1506 DTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVV-FQCDPGYELQGEE 1564
Query: 1256 TLTCLSGDRR-VWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 1314
+TC+ + R W P CIA CGG + +SG ILSP +P PY ++ C W I +
Sbjct: 1565 RITCIQVENRYFWQPSPPVCIAPCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNAD 1623
Query: 1315 KTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFF 1374
ISL FI F E +D L ++DGP + L+ + S LPE I S+ N++ L F SD
Sbjct: 1624 YVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS 1683
Query: 1375 ISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQ 1434
+S +GF +++ + +C DPG NGTR G + G TVT+ CD GY LQG + +TC+
Sbjct: 1684 VSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIM 1743
Query: 1435 LNN-RFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALI 1493
++ R W P+C A CG TG G +LSPNYP+ Y G C + + V +FV+
Sbjct: 1744 GDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQ 1803
Query: 1494 FKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIE-SSGNSLFLAFRSDASVGLSG 1552
F F +D + +Y+G S L+ S GS + E + SSGN + + F S + G
Sbjct: 1804 FVFFQTS-LHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKG 1862
Query: 1553 FAIEFKEKPREA---CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGA 1609
F ++ PR + C G R+G +F +GS++ + C+ GY + +I C
Sbjct: 1863 FHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVP 1922
Query: 1610 DGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFA 1669
+ W+ LP+C PCGG T +G +LSP YP Y C++ ITVP+ + Q
Sbjct: 1923 NSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVV 1982
Query: 1670 YFQTALN-DLAELFDGTHAQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASAR 1725
F T N D + +DG A L GS+SG T+P +TSN + L F + SA
Sbjct: 1983 SFATEHNWDSLDFYDGGDNNAPRL----GSYSGTTIPHLLNSTSNNLYLNFQSDISVSAA 2038
Query: 1726 GFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSV 1785
GFH Y A+ S C P G +IG + G +V F+C+ GY LQG + + C +
Sbjct: 2039 GFHLEYTAIGLDS---CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITC--M 2093
Query: 1786 PNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQV 1845
P + +WN IP C+ C G + G ILSPG+P Y ++L+C W I + G G+ +Q
Sbjct: 2094 PGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQF 2153
Query: 1846 ISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFH 1905
++F+TE D LE+ G T+ +G SG +P+ L ST+++ L+F SD S GFH
Sbjct: 2154 VNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFH 2213
Query: 1906 LEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWN 1965
+ Y+ L +C +P N IG+ + V +SF+C PGYTL G S ++C+ G R WN
Sbjct: 2214 IVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWN 2273
Query: 1966 YPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN 2025
+P P C A CGG ++ + G I SPG+P YPN DC W + +P G G +I F TE
Sbjct: 2274 HPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2333
Query: 2026 HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 2085
+DF+ + +GP SP IGQFSG ++ ST+++ LI F+SD + + F L+Y AY+L
Sbjct: 2334 YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS-GFFVLSYHAYQL 2392
Query: 2086 QNCPDPPPFQNGYMINSD--YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
+ C PPP N ++ D + +G + ++C PG+ L+G+ +LTC+ G + P C
Sbjct: 2393 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2452
Query: 2144 DAPCGYNV--TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYI 2201
C N G I SPG+PD YP L+ C W I+V G+ + + QTE D +
Sbjct: 2453 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2512
Query: 2202 AVWDGPDQNSPQLGVFSGN-TALETAYSSTNQVLLKFHSDFSNG-GFFVLNFHAFQLKKC 2259
V+DGP+ SP L SG+ ++ S+ ++V L++ +D N F + + AF C
Sbjct: 2513 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY---C 2569
Query: 2260 QPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCE 2317
P + P ++++ ++ V++ C G+ LVG C+ SS ++ +P C+
Sbjct: 2570 STPESPPHGYIISQTGG-QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 2318 A-QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVD---TFQSEKQF 2373
A C + T +G IL+ Y + C+ ++ T T+ + +
Sbjct: 2629 AISCGIPKAPT--NGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKT 2686
Query: 2374 DALEVFDGSSGQSPLLV-----VLSGNHTEQSN---FTSRSNQLYLRWSTDHATSKKGFK 2425
V S S +L +++G+H E F+ L ++ +
Sbjct: 2687 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2746
Query: 2426 IRYAAPYCSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGM 2481
R PYC + P G T + GS + C G+ +VG + C + L
Sbjct: 2747 WRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL-- 2804
Query: 2482 YQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQED 2541
W C A CGIPE NG G + VVY+C+ GF+L S + +CQ+D
Sbjct: 2805 --WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS--SVRICQQD 2860
Query: 2542 GLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLL 2601
WS G+ P+C PV+C + I+ SG+ + V SC+ GY ++G
Sbjct: 2861 HNWS--GQLPSCVPVSCGHPGSP-----IYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKA 2913
Query: 2602 RCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT----VYGATAIFTCNTGYTLVG 2657
+CQAN W+ P C+V++C P N + + YG + CN GY L G
Sbjct: 2914 QCQANRQWS--HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFG 2971
Query: 2658 SHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTS 2717
S V C NG W C+ CG P N +SG+ +++ TV Y C L+G S
Sbjct: 2972 SSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQS 3031
Query: 2718 VRICLQDHKWSGQTPVC---VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
R C + WSG P C TCG PG P HG S F V + C+TGY+L G
Sbjct: 3032 SRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGS 3091
Query: 2775 SRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL 2834
C +NG W+ P C+ V C +PG N G+ + + S++Y C +G+ L
Sbjct: 3092 EERTCLANGSWTGRQPECKAVQCGNPGTTAN----GKVFRIDGTTFSSSVIYSCMEGYIL 3147
Query: 2835 LGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRG--SESL 2892
G S C ANG W +LP C ISCG PG+PAN + G+ + G V Y C+ + L
Sbjct: 3148 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMEL 3207
Query: 2893 IGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQ 2952
G+ R C + WSG +P C C P ++G G +F + + C G++
Sbjct: 3208 NGSRIRTCTINGTWSGVMPTCRAVT---CPTPPQISNGRLEGTNFDWGFSISYICSPGYE 3264
Query: 2953 LRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKT 3012
L TC+ NG+WSG P C CG+PG P G ++ S V ++C +
Sbjct: 3265 LSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK-REGKSFIYQSEVSFSCNFPFIL 3323
Query: 3013 SGLMTRHCTANGTWTGTAPDC---TIISCGDPGTLANGIQFGT-DFTFNKTVSYQCNPGY 3068
G TR C A+GTW+G++P C T SC +PG +G Q T F V + C G+
Sbjct: 3324 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGH 3383
Query: 3069 VMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDF-RWGSSISYSCMDG 3127
+++ T+ T C D W+ +P C C QP + V G D G ++ Y+C G
Sbjct: 3384 LLQGSTTRT--CLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPG 3441
Query: 3128 YQLS-HSAILSCEGRGVWKGEIPQC---LPVFCGDPGIPAEGRLSGKSFTYKSEVFFQ 3181
+ L+ + C W G++P C + DP PA G S K + +VF Q
Sbjct: 3442 FFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPR-PALGTPSPK-LSVPDDVFAQ 3497
Score = 1487 bits (3849), Expect = 0.0
Identities = 998/3079 (32%), Positives = 1480/3079 (48%), Gaps = 216/3079 (7%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
K + CG +QGP+GT SP FP Y + A C W+I N+ IQ++F F LE +D L
Sbjct: 544 KVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTL 603
Query: 87 SVYDGQPQQGNLKVR--LSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
++ DG V L+G +P IVS S + L TD +V + GFK Y+ + +
Sbjct: 604 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 663
Query: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
CG+PG L G+ G F+ D +R+ C G+ L G + C W P C
Sbjct: 664 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPICIF 719
Query: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
C ++ SP +P Y NN +C WTI+++PG I L F DF LE +DFL +
Sbjct: 720 P--CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 777
Query: 265 SGTEAPSI----WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
++P TG +PS + S+ + LRL F +D + +GFN +
Sbjct: 778 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN---------- 827
Query: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
+ CPDPGIP N RR G +F ++G+++ CE+ +
Sbjct: 828 ----------------------TFGHNECPDPGIPINARRFGDNF-QLGSSISVICEEGF 864
Query: 381 V-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+ QG+++ITC + + WS P C A CG + PSGVI SP +P Y+D+ +C
Sbjct: 865 IKTQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCE 922
Query: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
WVI +P IK+ FE F+ E YD L V D + +L G+ VP + S SN
Sbjct: 923 WVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNL--LSPLLGSYNGTQVPQFLFSSSN 979
Query: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKG--GCGDPGIPAYGKRTGSSFLHGDTLTFECPAA 557
++L +D+S + GFK Y+ + C DPGIP +G+R G F G T++F C +
Sbjct: 980 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 1039
Query: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
+ L E + C++N+ WS P+C C + SG ILSP YPE Y N++NC W +
Sbjct: 1040 YRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV 1099
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIVRLE 674
G + F+ F +E D+L + ++G S L +G+++P + + +L
Sbjct: 1100 THGKGVQFNFHTFHLEDHHDYLLITENG-SFTQPLARLTGSDLPPTINAGLYGNFRAQLR 1158
Query: 675 FQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGS 734
F SD S + GFNIT++ + C DPGIP G R G F +G +++F C G+ + +G+
Sbjct: 1159 FISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGT 1217
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
I C L G VWS+ +PRC A CG T + G++L P +P Y+++ C + I+ + G
Sbjct: 1218 SEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAG 1276
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF-LISTGNFMYLLFTTDN 853
I I+ F D L++ DG ++ L+G + G L ST N ++L F +D
Sbjct: 1277 KGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDT 1335
Query: 854 SRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEP 911
+ GF + Y S E C DPGIP G++ G F ST+ + C+PGYTL
Sbjct: 1336 EGTDEGFQLVYTS--FELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSL 1392
Query: 912 LVCERNHQ--WNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHGKG 968
L C + W++ LPSC A CGG +G+ SG +LSPG+P Y N+L C W IEV G
Sbjct: 1393 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1452
Query: 969 VQMIFHTFHLESSHDYLLITEDGSFSEPVAR-LTGSVLPHTIKAGLFGNFTAQLRFISDF 1027
V + F F E+SHD L + + ++ + + ++GS++P I + L ++F +DF
Sbjct: 1453 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL---NIVTIQFDTDF 1509
Query: 1028 SISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCL 1087
IS GF I FS C DPGVP R G GD++ F C GY L+G ++TC+
Sbjct: 1510 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCI 1569
Query: 1088 G-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 1146
R W P C+A CG ++ G+ G +LSPNFP Y ++ +C + I A I L
Sbjct: 1570 QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1629
Query: 1147 TRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQG 1205
SF + D L +YDG DS+S +G+F ++L I S+SN + L F ++GS + G
Sbjct: 1630 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI-ESSSNTMHLAFRSDGSVSYTG 1688
Query: 1206 FQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD-- 1263
F L Y + C DPG G R+ + TV Y C+ GY + G +TLTC+ GD
Sbjct: 1689 FHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYY-CDAGYVLQGYSTLTCIMGDDG 1747
Query: 1264 RRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIV 1323
R W++ LPSC A CG + + G +LSP YP Y +C + I + F+
Sbjct: 1748 RPGWNRALPSCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVF 1806
Query: 1324 FDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSGFSI 1382
F T + HD+++V+DGP LL SGS E + S+ N +T++F S I+ GF
Sbjct: 1807 FQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHF 1865
Query: 1383 QFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
+ + + C+ P+ G R G+ G +V F C+PGY L G I C + N
Sbjct: 1866 VYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1925
Query: 1440 F-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
W PTCI CGG LT G ILSP YP+PY C W++ V I + SF
Sbjct: 1926 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFA 1985
Query: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
E ++D L Y+G D+N+P +GSY G+ P + S+ N+L+L F+SD SV +GF +E+
Sbjct: 1986 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 2045
Query: 1559 EKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQV 1618
++C +P +G ++G + +G +++QCD GY + S ITC+ G + W+
Sbjct: 2046 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYP 2103
Query: 1619 LPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALND 1677
+P C A CGG + GV+LSP +P NY + C ++I +P F V QF F T ++D
Sbjct: 2104 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2163
Query: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
E+ G+ + ++ LSG +L +T+++ L F + + +GFH VYQA
Sbjct: 2164 YLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY--- 2219
Query: 1738 SDTQCSSVPEPRYGRR---IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Q S P+PR R IG++F+ G + FEC PGY L G++AL C + WN
Sbjct: 2220 ---QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNH 2274
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
+P C C GN T GTI SPGYP+ Y N +C W + V G+GI I TE +
Sbjct: 2275 PLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY 2334
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D + + DG D +P++G FSG T + STSNQ+ + F SD + + F L Y L
Sbjct: 2335 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLR 2393
Query: 1915 ACQEPALPSNS--IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
CQ P N+ + D + + D++ +QC PG+TL G + ++C G + + P+C
Sbjct: 2394 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2453
Query: 1973 ATCGGTLSTLG--GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
C L GVILSPG+P SYPN C W IS+ GY + F TE D L+
Sbjct: 2454 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2513
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAA--LLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
+ +GP SP++ SG D +A + S HE + + +DH N++GF++ Y A+ +
Sbjct: 2514 VYDGPNIQSPVLISLSG-DYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYC-ST 2571
Query: 2089 PDPPPFQNGYMIN-SDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFPRCD 2144
P+ PP +GY+I+ + + V + C G+ L+G C+ +G + W+ P P C
Sbjct: 2572 PESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHA-WDAPVPACQ 2628
Query: 2145 A-PCGYNVTSQNGTIYSPGF----------PDEYPI-LKDCIWLITVPPG----HGVYIN 2188
A CG NG I + + D Y + K+ + G H
Sbjct: 2629 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2688
Query: 2189 FTLLQTEAVNDYI------AVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2242
++ ++N +I + +G VFS + ++ + L
Sbjct: 2689 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL-------P 2741
Query: 2243 NGGFFVLNFHAF-QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTC 2301
NG + N + Q+ C P P + + G + C G+ LVG+ + C
Sbjct: 2742 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVREC 2799
Query: 2302 KLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNIT 2361
LSS L E C E+ +G ++ Y C+ ++ +
Sbjct: 2800 -LSSGLWSESETRCLAGHCGIPELIV--NGQVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2856
Query: 2362 IFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRS-NQLYLRWSTDHATS 2420
D S + + V G G SP+ SGN ++ + S N YL A
Sbjct: 2857 CQQDHNWSGQLPSCVPVSCGHPG-SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC 2915
Query: 2421 KKGFKIRYAAPYCSLTHPLKNGGILNRTAGA--------VGSKVHYFCKPGYRMVGHSNA 2472
+ + + P C + + G N + G+ V Y C PGY + G S
Sbjct: 2916 QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL 2975
Query: 2473 TCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ 2532
C+ N QWD P C + CG P P N +G ++T S V Y C K
Sbjct: 2976 ICQPNG----QWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTG--KRSLLG 3029
Query: 2533 QATAVCQEDGLWSNKGKPPTCKPVACPSI-EAQLSEHVIWRLVSGSLNEYG----AQVLL 2587
Q++ CQ +G WS G P C A + + H GS E + V
Sbjct: 3030 QSSRTCQLNGHWS--GSQPHCSGDATGTCGDPGTPGH-------GSRQESNFRTKSTVRY 3080
Query: 2588 SCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATA 2645
+C GY L G C ANG+W +P C+ + CG+ NG K+ + T + ++
Sbjct: 3081 ACDTGYILHGSEERTCLANGSWT--GRQPECKAVQCGNPGTTANG-KVFRIDGTTFSSSV 3137
Query: 2646 IFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVY 2705
I++C GY L G VR+C ANG WSG+ C CG P NG GD + V Y
Sbjct: 3138 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSY 3197
Query: 2706 QCNPGF--RLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNF 2763
C PG+ L G+ +R C + WSG P C +TC P ++G G+ F+ +++
Sbjct: 3198 MCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISY 3257
Query: 2764 TCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823
C+ GY L + C NG WS +P C C DPG R G +SF Y
Sbjct: 3258 ICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREG-----KSFIYQSE 3312
Query: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKCL---AISCGHPGVPANAVLTGEL-FTYG 2879
+ + C F L+GSS C A+G W S P C+ SC +PGVP + F G
Sbjct: 3313 VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG 3372
Query: 2880 AVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKT 2939
+VV + C+ L G+ TR C D WSG P C P C P TPAH + +G D +
Sbjct: 3373 SVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI---PHSCKQPETPAHANVVGMDLPS 3429
Query: 2940 KS-LLRFSCEMGHQLRGSPE-RTCLLNGSWSGLQPVCEA---VSCGNP----GTPTNGMI 2990
L ++C+ G L G E R C + +W+G P+CEA + +P GTP+ +
Sbjct: 3430 HGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLS 3489
Query: 2991 VSSDGILFSSSVIYACWEG 3009
V D +F+ + I W+G
Sbjct: 3490 VPDD--VFAQNYI---WKG 3503
Score = 1297 bits (3356), Expect = 0.0
Identities = 908/2900 (31%), Positives = 1325/2900 (45%), Gaps = 244/2900 (8%)
Query: 39 PNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNL 98
P GT+ SP +P GY N NC W II+ +RI LSF+ F LE FD L+V DG + +
Sbjct: 728 PMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPI 787
Query: 99 KVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHG 158
+G ++PS + S IL L F D ++S +GF Y + C +PG + G
Sbjct: 788 LGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFG 847
Query: 159 TRFNIGDKIRYSCLPGYI-LEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSS 217
F +G I C G+I +G +TCI+ G W P C A CGG S
Sbjct: 848 DNFQLGSSISVICEEGFIKTQGTETITCILMDGK-VMWSGLIPKCGA--PCGGHFSAPSG 904
Query: 218 SISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIW---- 273
I SP +P Y+++ +C W I AEPG +I + F FQ E YD LE+ + P++
Sbjct: 905 VILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLL 962
Query: 274 --LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGS 331
G +P + SS N++ L FT+D++ GF ++
Sbjct: 963 GSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYE--------------------- 1001
Query: 332 HKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQ 391
V + + C DPGIP +GRR G DFS +G+ V FSC+ Y L + + C
Sbjct: 1002 ---------SVTVNTYSCLDPGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLC- 1050
Query: 392 RVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVI 451
E WS P C A CG ++RGPSG I SP YP Y ++ +C W + T K +
Sbjct: 1051 ---EKNHWWSHPLPTCDA-LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTH-GKGV 1105
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLI---VSMSNQMWLHLQSD 508
+ F F LE +D L + + G L LTGS +P I + + + L SD
Sbjct: 1106 QFNFHTFHLEDHHDYLLITENGSF---TQPLARLTGSDLPPTINAGLYGNFRAQLRFISD 1162
Query: 509 DSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITC 568
SI GF + E C DPGIP YG R G +F GDTLTF C + + L G I C
Sbjct: 1163 FSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIIC 1222
Query: 569 QQNNQ--WSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLI 626
+ WS P CV C + T + GI+LSPNYP Y NN C++ I + G I++
Sbjct: 1223 LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINIS 1282
Query: 627 FNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPS-QLASSGHIVRLEFQSDHSTTGRG 685
F + Q D L + D +LG F+G + L+S+ + + LEF SD T G
Sbjct: 1283 ARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEG 1341
Query: 686 FNITYTTFGQNECHDPGIPINGRRFGDR-FLLGSSVSFHCDDGFVKTQGSESITCILQDG 744
F + YT+F + C DPGIP G + D+ GS++ + C+ G+ GS + C+ +
Sbjct: 1342 FQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYT-LHGSSLLKCMTGER 1400
Query: 745 NVVWSSTVPRCEAPCGGHLTA-SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDR 803
W +P C A CGG SSG IL PG+P Y ++L C W+IE PG+ + + F
Sbjct: 1401 R-AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLA 1459
Query: 804 FQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIH 863
F TE ++D L V DGP + L+ E G+ P+ + ST N + + F TD S GF I
Sbjct: 1460 FDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQ 1519
Query: 864 YESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVC---ERNHQW 920
+ S + +C DPG+P+NG R+G TV F CDPGY L +E + C E + W
Sbjct: 1520 FSSSV--ATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFW 1577
Query: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
+ P C A CGG + G SG +LSP FP YP+S +C WTI V+ + + F +F +E
Sbjct: 1578 QPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEP 1637
Query: 981 SHDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
++D+L I + + P + S LP I++ + T L F SD S+SY GF++ +
Sbjct: 1638 NYDFLYIYDGPDSNSPLIGSFQDSKLPERIES---SSNTMHLAFRSDGSVSYTGFHLEYK 1694
Query: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGG--GRRVWSAP 1097
E C DPG R+G + +G ++T+ C GY L+G + LTC+ G GR W+
Sbjct: 1695 AKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRA 1754
Query: 1098 LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT 1157
LP C A CG+ G+EGT+LSPN+P NY H C+Y I + + FQ D
Sbjct: 1755 LPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV 1814
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSF---D 1214
++VYDG S L + + + + S+ N + + F + G T +GF Y +
Sbjct: 1815 VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTS 1874
Query: 1215 LVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC--LSGDRRVWDKPLP 1272
+C P +G RI +E + VL+ CNPGY +HGS + C + W+ LP
Sbjct: 1875 STQCSSVPEPRFGRRIGNE-FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLP 1933
Query: 1273 SCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDI 1332
+CI CGG I G ILSPGYP PYDNNL+C W I G I + + F TE D
Sbjct: 1934 TCIVPCGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDS 1992
Query: 1333 LKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATC 1392
L +DG ++ L +SG+ +P ++ST N+L L F SD +S +GF ++++ +C
Sbjct: 1993 LDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC 2052
Query: 1393 NDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAAC 1452
+P P +G + GD GD V+FQCD GY LQG + ITC+ R W P C+A C
Sbjct: 2053 PEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVR-RWNYPIPICLAQC 2111
Query: 1453 GGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGE 1512
GG ++ +GVILSP +P YP +C W + + F + L F +F+ E +D+L + G
Sbjct: 2112 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2171
Query: 1513 DSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIM 1572
S +IG G Q P + S+ + L F SD S GF I ++ ++C DP
Sbjct: 2172 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFR 2231
Query: 1573 NGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTG 1632
NG +G DF +G TI+++C GY ++ S++TC+ G +W+ LP C A CGG T
Sbjct: 2232 NGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRCEALCGGNITA 2289
Query: 1633 SEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALNDLAELFDGTHAQARL 1691
G + SP YP Y Q C + + VP ++ F QT + D ++DG +
Sbjct: 2290 MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQ 2349
Query: 1692 LSSLSGSHSGETLPLATSNQILLRFSA---KSGASARGFHFVYQAVPRTSDTQCSSVPEP 1748
+ SG+ + E++ +TSNQIL++F + SG +H YQ + P P
Sbjct: 2350 IGQFSGNTALESV-YSTSNQILIKFHSDFTTSGFFVLSYH-AYQ-------LRVCQPPPP 2400
Query: 1749 RYGRRI---GSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSG 1805
I EF G I+R++C PG+ L G+ L C+ Q + P C V C
Sbjct: 2401 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRL--GERLQMDGAPPVCQVLCPA 2458
Query: 1806 NFTQ--RRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGG 1863
N + G ILSPGYP+ Y N C W I V +G I + V F TE+ +D L+++DG
Sbjct: 2459 NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP 2518
Query: 1864 DVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALP 1922
++ +P L S SG A + S ++++L + +D GF + Y C P P
Sbjct: 2519 NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTPESP 2575
Query: 1923 SNSIKIGDR-YMVNDVLSFQCEPGYTLQGRSHISCMPGT--VRRWNYPSPLCIA-TCGGT 1978
+ I +N V+ + C+ G+ L G+S C + W+ P P C A +CG
Sbjct: 2576 PHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIP 2635
Query: 1979 LSTLGGVILSPGFPGSYPNNLDCT--WRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPY 2036
+ G IL+ + C +R+S A Q + T +NH+ +
Sbjct: 2636 KAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQ--SDGTWSNHN--KTPRCVV 2691
Query: 2037 HTSPMIGQFSGTDLPAALLSTTH---ETLIHFYSDHSQNRQG-------------FKLAY 2080
T P I F +++ +H +T + F D + G ++
Sbjct: 2692 VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNER 2751
Query: 2081 QAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYP 2139
++ +C + P NG I + S G + F C G++L+G V C G+ W+
Sbjct: 2752 PYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL---WSES 2808
Query: 2140 FPRCDA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN 2198
RC A CG NG + + ++ C PG + + + + N
Sbjct: 2809 ETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQC------NPGFRLIGSSVRICQQDHN 2862
Query: 2199 DYIAVWDGP----------DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFV 2248
W G SP G SGN ++ + V + + G
Sbjct: 2863 -----WSGQLPSCVPVSCGHPGSPIYGRTSGN-----GFNFNDVVTFSCNIGYLMQGPTK 2912
Query: 2249 LNFHAFQLKKCQPP------------PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGT 2296
A + PP PA + E E +F G V Y C+PGY L G+
Sbjct: 2913 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2972
Query: 2297 DILTCKLSSQLQFEGSLPTC------EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSW 2350
+L C+ + Q++ LP C P N V +G Y +C+
Sbjct: 2973 SVLICQPNG--QWDKPLPECIMIDCGHPGVPPNAVLSGEK-------YTFGSTVHYSCTG 3023
Query: 2351 SIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLY 2410
+ + T ++ S Q G+ G ++SNF ++S Y
Sbjct: 3024 KRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKSTVRY 3080
Query: 2411 -------LRWSTDHAT----SKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYF 2459
L S + S G + A C NG + S V Y
Sbjct: 3081 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYS 3140
Query: 2460 CKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVV 2519
C GY + G S C N W P C +SCG P P NG G+++ + V
Sbjct: 3141 CMEGYILSGPSVRQCTANG----TWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVS 3196
Query: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
Y C G+ +E + C +G WS G PTC+ V CP+ Q+S + G+
Sbjct: 3197 YMCQPGYTMELNGSRIRTCTINGTWS--GVMPTCRAVTCPT-PPQISN----GRLEGTNF 3249
Query: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT 2639
++G + CSPGY L +L C NGTW+ E P C CG P G + G
Sbjct: 3250 DWGFSISYICSPGYELSFPAVLTCVGNGTWS--GEVPQCLPKFCGDPGIPAQGKREGKSF 3307
Query: 2640 VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL-AGHCGSPDPIVNGHISGD--- 2695
+Y + F+CN + LVGS R C A+G WSGS C+ +P V H S +
Sbjct: 3308 IYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF 3367
Query: 2696 GFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEF 2755
GF V + C G L G++ R CL D WSG P C+P +C P PAH G +
Sbjct: 3368 GFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDL 3427
Query: 2756 NLND-VVNFTCNTGYLLQ-GVSRAQCRSNGQWSSPLPTCRV------------------- 2794
+ + +TC G+ L G CRS+ W+ +P C
Sbjct: 3428 PSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPK 3487
Query: 2795 VNCSDPGFVENAIRHGQQNF 2814
++ D F +N I G NF
Sbjct: 3488 LSVPDDVFAQNYIWKGSYNF 3507
Score = 414 bits (1065), Expect = e-115
Identities = 187/279 (67%), Positives = 227/279 (81%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
CGG ++G NGTIESPGFP+GYPN ANCTW+II ERNRIQ+ F +FALEE++D LS+YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEI 151
P N + RL+GF LP + ST S+ +L T+DFAVSA GFK YE L S +CGNPG
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
Query: 152 LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGT 211
KGVL+GTRF++GDKIRYSC+ GYIL+GH LTCI + N ASWDFP P CRAE ACGGT
Sbjct: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
Query: 212 LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPS 271
+RG+S ISSP FP+EY NNADCTWTI+AEPGDTI+L+FTDFQ+EE YD+LEI G+E P+
Sbjct: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
Query: 272 IWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
IWL+GMN+P P+IS+KNWLRLHF +DSNHR +GF+A +Q
Sbjct: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 184 bits (467), Expect = 1e-45
Identities = 112/319 (35%), Positives = 159/319 (49%), Gaps = 45/319 (14%)
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI-SG 266
CGGTL+G + +I SP FP Y N A+CTW I+AE + I +VF F LEE YD+L + G
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 267 TEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVK 323
P+ + LTG +LP PV S+K+ L TSD GF ++
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE------------- 171
Query: 324 MLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQ 383
L S C +PG+P G G+ F VG +++SC Y+L
Sbjct: 172 -------------------ELQSSSCGNPGVPPKGVLYGTRFD-VGDKIRYSCVTGYILD 211
Query: 384 GSKSITCQRVTETLAAWSDHRPICRAR-TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVI 442
G +TC + A+W PICRA CG +RG SG+I+SP++P +Y +NA C W I
Sbjct: 212 GHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI 271
Query: 443 TTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMW 502
+P I L F +F++E YD L + G ++ L+G ++P I+S N +
Sbjct: 272 -VAEPGDTISLIFTDFQMEEKYDYLEI-----EGSEPPTIW-LSGMNIPPPIISNKNWLR 324
Query: 503 LHLQSDDSIGSPGFKAVYQ 521
LH +D + GF A YQ
Sbjct: 325 LHFVTDSNHRYRGFSAPYQ 343
Score = 181 bits (460), Expect = 9e-45
Identities = 97/286 (33%), Positives = 144/286 (50%), Gaps = 8/286 (2%)
Query: 1800 VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEI 1859
+ C G GTI SPG+P Y N NC W II E + IQI SFA E+ +D L +
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 1860 HDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEP 1919
+DG +G +P + ST + L SD +V+A GF + Y+ + ++C P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 1920 ALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVR--RWNYPSPLCIA--TC 1975
+P + G R+ V D + + C GY L G ++C+ +V W++P P+C A C
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 241
Query: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP 2035
GGT+ G+I SP FP Y NN DCTW I G + F +F E +D+LEI+
Sbjct: 242 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEG-- 299
Query: 2036 YHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQ 2081
+ P SG ++P ++S + +HF +D + +GF YQ
Sbjct: 300 --SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 177 bits (448), Expect = 2e-43
Identities = 100/286 (34%), Positives = 152/286 (53%), Gaps = 13/286 (4%)
Query: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVG 470
TCG L+G +G I SP +P Y + A+C WVI + ++ I++ F+ F LE YD L++
Sbjct: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLY 122
Query: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
D + LTG +P + S + L L SD ++ + GFK Y+E++ CG+
Sbjct: 123 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN----QWSGNKPSC--VFS 584
PG+P G G+ F GD + + C + L G +TC N+ W P C +
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
C SSGII SP++P EY NN +C W I++EPG I LIF DF +E ++D+L + +
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--E 298
Query: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
G T+ SG +P + S+ + +RL F +D + RGF+ Y
Sbjct: 299 GSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 169 bits (428), Expect = 5e-41
Identities = 98/287 (34%), Positives = 144/287 (50%), Gaps = 8/287 (2%)
Query: 1275 IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILK 1334
I CGG + +G I SPG+P Y N +CTW+I A+ I + F F E +D L
Sbjct: 62 IYTCGGTLKGL-NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCND 1394
++DG +G LP + ST + +L+ SDF +S GF + + +++C +
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 1395 PGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTCIA--A 1451
PG+P G YG + GD + + C GY L G ++TC+ + N W P C A A
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
CGG + G +G+I SP++P Y +C W + P I+LIF F ME YD+L I
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--- 297
Query: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
E S P I G P I S+ N L L F +D++ GF+ ++
Sbjct: 298 EGSEPPTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 167 bits (424), Expect = 1e-40
Identities = 91/287 (31%), Positives = 140/287 (48%), Gaps = 8/287 (2%)
Query: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
+++C +G I SP +P Y N NC W+II+E +RI ++F F +E ++D+L++
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
D +G +P + S+ + L SD + + GF + Y + C +P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV-WSSTVPRCEA--P 758
G+P G +G RF +G + + C G++ G +TCI N W VP C A
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
CGG + SSG+I P +P Y ++ C W I A+PG +I + F FQ E YD LE+
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE-- 298
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE 865
S P G P +IS N++ L F TD++ GF Y+
Sbjct: 299 --GSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 166 bits (421), Expect = 3e-40
Identities = 101/288 (35%), Positives = 143/288 (49%), Gaps = 18/288 (6%)
Query: 931 CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITED 990
CGG ++G +GT+ SPGFP YPN NCTW I +Q++F +F LE +DYL + +
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD- 123
Query: 991 GSFSEPV---ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCD 1047
P RLTG LP + + LR SDF++S GF + + E C
Sbjct: 124 -GHPHPTNFRTRLTGFHLPPPVTS---TKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 1048 DPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRV--WSAPLPRCVAE- 1104
+PGVP G F VGD + +SC GY L+G +LTC+ W P+P C AE
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 1105 -CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYD 1162
CG +++G+ G + SP+FP+ Y NN +C + I E G I L FQ+ E D L++
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI-- 297
Query: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
S P + + + S N L L F T+ + +GF Y
Sbjct: 298 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 159 bits (403), Expect = 4e-38
Identities = 93/273 (34%), Positives = 134/273 (49%), Gaps = 8/273 (2%)
Query: 1972 IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
I TCGGTL L G I SPGFP YPN +CTW I I F +F+ E +D+L +
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+G H + + +G LP + ST + SD + + GFK+ Y+ + +C +P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC-QHGIN-RNWNYPFPRCDA--PC 2147
G + + + VG + + C GYIL GHP LTC + +N +W++P P C A C
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 241
Query: 2148 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGP 2207
G + +G I SP FP+EY DC W I PG + + FT Q E DY+ +
Sbjct: 242 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI---- 297
Query: 2208 DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
+ + P SG S+ N + L F +D
Sbjct: 298 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTD 330
Score = 159 bits (403), Expect = 4e-38
Identities = 97/286 (33%), Positives = 143/286 (50%), Gaps = 14/286 (4%)
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
CGG L +G I PG+P Y + +C W+I A+ + I+I F F E YD L + DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
+ G P + ST + L T+D + S+ GF ++YE L+S SC +PG
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEE--LQSSSCGNPG 182
Query: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNH----QWNHALPSCDA--LCG 932
+P G +G F + + +SC GY L L C N W+ +P C A CG
Sbjct: 183 VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 242
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGS 992
G ++G SG + SP FP+ Y N+ +CTWTI G + +IF F +E +DYL I +GS
Sbjct: 243 GTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--EGS 300
Query: 993 FSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
P L+G +P I + +L F++D + Y GF+ +
Sbjct: 301 -EPPTIWLSGMNIPPPI---ISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 138 bits (348), Expect = 9e-32
Identities = 105/296 (35%), Positives = 138/296 (46%), Gaps = 20/296 (6%)
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-DTLKVYDG 1163
CG ++KG GT+ SP FP Y N C + I E I + +SF L E D L +YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 1164 KDSSSRPLGTFTKNELLGLIL----NSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
P T + L G L ST + L ++ + + GF++ Y C
Sbjct: 125 -----HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL--SGDRRVWDKPLPSCIAE 1277
+PG+P G D + YSC GY + G LTC+ S + WD P+P C AE
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKI-RYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 1278 --CGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKV 1335
CGG + +SG I SP +P Y NN CTW I A+PG TISL F F E +D L++
Sbjct: 239 DACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
Query: 1336 WDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
+G I L SG +P I S N L L F +D GFS + S T
Sbjct: 298 -EGSEPPTIWL---SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 349
Score = 137 bits (345), Expect = 2e-31
Identities = 86/289 (29%), Positives = 129/289 (44%), Gaps = 12/289 (4%)
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
I CGG L G G I SP +P YP G C W + I ++F+SF +E YD+L +
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 1509 YEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP 1568
Y+G + G P + S+ + L SD +V GF + ++E +C +P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA--PC 1626
G G GT F +G I Y C +GY + +TC+ + SWD +P C A C
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDAC 241
Query: 1627 GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTH 1686
GG GS G++ SP++P+ Y C ++I + F FQ + E +D
Sbjct: 242 GGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQ-----MEEKYDYLE 296
Query: 1687 AQARLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQ 1732
+ ++ SG +P ++ N + L F S RGF YQ
Sbjct: 297 IEGSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 132 bits (333), Expect = 5e-30
Identities = 98/316 (31%), Positives = 142/316 (44%), Gaps = 22/316 (6%)
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
CG + NGTI SPGFP YP +C W+I + + I F E DY++++DG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 2207 ---PDQNSPQLGVFSGNTALETAYSSTNQVL-LKFHSDFSNGGF-FVLNFHAFQLKKCQP 2261
P +L F L +ST V L+ SDF+ F + + Q C
Sbjct: 125 HPHPTNFRTRLTGFH----LPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS--QLQFEGSLPTCEAQ 2319
P P+ + F++GD ++Y C GY L G LTC +S ++ +P C A+
Sbjct: 181 PGVPPKGVLY--GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 2320 CPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVF 2379
GSSG+I SP +P Y N+ C+W+I EP I++ FQ E+++D LE+
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 297
Query: 2380 DGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPL 2439
G P + LSG + S N L L + TD +GF Y +LTH
Sbjct: 298 ---EGSEPPTIWLSGMNIPPP-IISNKNWLRLHFVTDSNHRYRGFSAPYQGS-STLTHTT 352
Query: 2440 KNGGILNR---TAGAV 2452
G + T GA+
Sbjct: 353 STGELEEHNRTTTGAI 368
Score = 125 bits (314), Expect = 7e-28
Identities = 85/289 (29%), Positives = 124/289 (42%), Gaps = 15/289 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEF---VVFGQFAYFQTALNDLAELF 1682
CGG G G + SP +P+ Y G C + I + +VF FA + D L+
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEY--DYLSLY 122
Query: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQC 1742
DG + L+G H + +T + LR ++ SA GF Y+ + +S C
Sbjct: 123 DGHPHPTNFRTRLTGFHLPPPVT-STKSVFSLRLTSDFAVSAHGFKVYYEELQSSS---C 178
Query: 1743 SSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVV- 1801
+ P G G+ F G +R+ C GY+L G L C + A W+ +P C
Sbjct: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 1802 -PCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
C G G I SP +P Y NN +C W I+ G I + F E+ +D LEI
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI- 297
Query: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK 1909
+ + P SG +P + S N L LHF +D + GF Y+
Sbjct: 298 ---EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 93.6 bits (231), Expect = 3e-18
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSP 2387
G +G I SPG+P Y N C+W I E I I +F E+++D L ++DG +
Sbjct: 71 GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTN 130
Query: 2388 LLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA-PYCSLTHP-LKNGGIL 2445
L+G H TS + LR ++D A S GFK+ Y S +P + G+L
Sbjct: 131 FRTRLTGFHLPPP-VTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVL 189
Query: 2446 NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCG 2497
T VG K+ Y C GY + GH TC N + WD P+C+A +CG
Sbjct: 190 YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACG 242
Score = 53.1 bits (126), Expect = 5e-06
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 2738 TCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSN----GQWSSPLPTCR 2793
+CG+PG P G G+ F++ D + ++C TGY+L G + C +N W P+P CR
Sbjct: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Score = 52.4 bits (124), Expect = 8e-06
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN----GSWSGLQPVCEA 2976
CG+PG P G G F +R+SC G+ L G P+ TC+ N SW P+C A
Sbjct: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
Query: 2977 V-SCGNPGTPTNGMIVS 2992
+CG ++G+I S
Sbjct: 238 EDACGGTMRGSSGIISS 254
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 3037 SCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSAT--IRCTKDGRWNPSKPVCK 3094
SCG+PG G+ +GT F + Y C GY+++ T W+ P+C+
Sbjct: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Query: 3095 A 3095
A
Sbjct: 237 A 237
Score = 40.4 bits (93), Expect = 0.032
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 2796 NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGL----WDRS 2851
+C +PG + +G + F+ G I Y C G+ L G LTC+AN + WD
Sbjct: 177 SCGNPGVPPKGVLYGTR-----FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 231
Query: 2852 LPKCLA-ISCG 2861
+P C A +CG
Sbjct: 232 VPICRAEDACG 242
Score = 40.0 bits (92), Expect = 0.041
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 2859 SCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDS----HWSGALPHCT 2914
SCG+PGVP VL G F G + YSC L G+ C +S W +P C
Sbjct: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Query: 2915 GNNPGFCG 2922
+ CG
Sbjct: 237 AEDA--CG 242
Score = 37.7 bits (86), Expect = 0.21
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 3156 CGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD----GTWSGIQPTC 3209
CG+PG+P +G L G F ++ + C + +IL G + C A+ +W P C
Sbjct: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Score = 37.0 bits (84), Expect = 0.35
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 3215 NTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLAN 3261
++C +PG P G+ +R ++VG + + C GY + G TC+AN
Sbjct: 176 SSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIAN 221
Score = 36.2 bits (82), Expect = 0.60
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 2622 SCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCL 2677
SCG+ PP G GT G ++C TGY L G C+AN + W C
Sbjct: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Query: 2678 A-GHCGSPDPIVNGHISGDGF 2697
A CG +G IS F
Sbjct: 237 AEDACGGTMRGSSGIISSPSF 257
Score = 35.8 bits (81), Expect = 0.78
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGV----WKGEIPQC-L 3152
C P G + G+ F G I YSC+ GY L L+C V W +P C
Sbjct: 178 CGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
Query: 3153 PVFCGDPGIPAEGRLSGKSF 3172
CG + G +S SF
Sbjct: 238 EDACGGTMRGSSGIISSPSF 257
Score = 34.3 bits (77), Expect = 2.3
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 6/79 (7%)
Query: 2975 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN----GTWTGTA 3030
++ SCGNPG P G++ + + Y+C GY G C AN +W
Sbjct: 174 QSSSCGNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 232
Query: 3031 PDCTI-ISCGDPGTLANGI 3048
P C +CG ++GI
Sbjct: 233 PICRAEDACGGTMRGSSGI 251
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 4341 bits (11259), Expect = 0.0
Identities = 2006/3239 (61%), Positives = 2475/3239 (76%), Gaps = 70/3239 (2%)
Query: 29 GQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSV 88
GQNC + GPNGT+ESPGFP+GYPNYANCTW I E++RIQL F +FALEEDFD+LSV
Sbjct: 23 GQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV 82
Query: 89 YDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
+DG PQ NL+ RL+GFQLP++IVS + L+L +D+AVSAQGF A YEVLPSHTCGNP
Sbjct: 83 FDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNP 142
Query: 149 GEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
G + G+ G+ FN+GDK+RYSC G+ LEGHA+LTC N A+WDFP P CRA+ AC
Sbjct: 143 GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
Query: 209 GGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTE 268
GGTLRG S ISSPHFPSEY NNADCTWTILAE GDTIALVF DFQLE+GYDFLE++GTE
Sbjct: 203 GGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTE 262
Query: 269 APSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSK 328
S+W TG +LP+PVISSKNWLRLHFTSD NHR++GF+AQ+QVKK IELKSRGVK++PSK
Sbjct: 263 GSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
Query: 329 DGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSI 388
D S K SVL+Q GV+ +MCPDPGIPE G+R GSDF R+G++VQF+C + Y LQGSK I
Sbjct: 323 DNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDF-RLGSSVQFTCNEGYDLQGSKRI 381
Query: 389 TCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPD 448
TC +V++ AAWSDHRP+CRAR C ++LRGPSG+ITSPN+P+QY++NAHCVW+IT +P
Sbjct: 382 TCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPS 441
Query: 449 KVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSD 508
KVIKLAFEEF+LERGYDTLTVGD G+ GD ++VLY+LTG+SVPDLIVS ++QMWL Q+D
Sbjct: 442 KVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTD 501
Query: 509 DSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITC 568
S S GFKA Y+EIE+G CGDPGIPAYG+R GS F HGDTL FEC AFELVG++ ITC
Sbjct: 502 GSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC 561
Query: 569 QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFN 628
Q+NNQWS KP CVFSCFFNFT+ SG++LSPNYPE+YGN+++CVWLI++ P SRIHL FN
Sbjct: 562 QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFN 621
Query: 629 DFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNI 688
D DVEPQFDFL +KD ++ VLGTFSGN++PS + SSGH+ RLEFQ+DHST RGFNI
Sbjct: 622 DIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNI 681
Query: 689 TYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVW 748
T+TTF NEC DPG+P+NG+RFGD LGSS+SF CD+GF+ TQGSE+ITC+L++G+VVW
Sbjct: 682 TFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVW 741
Query: 749 SSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEV 808
+S V RCEAPCGGHLT+ SG IL PGWPG+YKD+L C W+IEA+PG+ IKITFDRF+TEV
Sbjct: 742 NSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEV 801
Query: 809 NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVT 868
NYDTLEVRDG S+PLIG YHGTQ PQFLIST N++YLLF+TD S S IGF + YE++T
Sbjct: 802 NYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETIT 861
Query: 869 LESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
L+SD CLDPGIPVNG RHG DF + + VTFSCD GYTLSD EPL CE N QW+ ALPSC+
Sbjct: 862 LQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 921
Query: 929 ALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLIT 988
ALCGG+IQG SGT+LSPGFPDFYPN+LNCTW IE SHGKGV FHTFHLES HDYLLIT
Sbjct: 922 ALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLIT 981
Query: 989 EDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDD 1048
E+GSF++P+ +LTGS LP I AGL+GNFTAQ+RFISDFS+SYEGFNITFSEYDLEPC++
Sbjct: 982 ENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEE 1041
Query: 1049 PGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGAS 1108
P VPA+S R G FGVGD+LTFSCF GYRLEG ++TCLGG RR+WS+PLPRCVAECG S
Sbjct: 1042 PEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNS 1101
Query: 1109 VKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSS 1168
V G +GTLLSPNFP NY+NNHECIY I+T+ GKGI L+ R+F+L EGD LKVYDG ++S+
Sbjct: 1102 VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSA 1161
Query: 1169 RPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGY 1228
R LG F+ +E++G+ LNSTS+ LWL+F T+ +T +GF+L ++SF+L+KCEDPG P +GY
Sbjct: 1162 RLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGY 1221
Query: 1229 RIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSG 1288
++ DEGHF + V +SC+PGY++ GS L CLSG+RR WD+PLP+C+AECGG + SG
Sbjct: 1222 KVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSG 1281
Query: 1289 RILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKE 1348
++LSPGYPAPY++NL+C W IEA+ G TI LHF+VFDTE HD+L++WDGPV+S +LLKE
Sbjct: 1282 QVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKE 1341
Query: 1349 WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSR 1408
SG ALP+D+HSTFNS+ LQF +DFF SK GF+IQFS S A +CNDPG+PQNG+R GDS
Sbjct: 1342 LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSW 1401
Query: 1409 EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNY 1468
EAGD+ FQCDPGY LQG A+I+CV++ NRFFWQP PPTCIA CGG+LTGP+GVILSPNY
Sbjct: 1402 EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNY 1461
Query: 1469 PQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAP 1528
P+PYPPGKECDW+V V+PD+VIAL+F FN+EP YDFLHIY+G DS SPLIGS+ GSQ P
Sbjct: 1462 PEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP 1521
Query: 1529 ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTIT 1588
RIESS NSLFLAFRSDASV +GF I++ E PRE+CFDPG+I NGTRVG+D KLGS++T
Sbjct: 1522 GRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVT 1581
Query: 1589 YQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTA 1648
Y C GY++ S+++C++G DGKP W+ P C APCGGQY GS+GVVLSPNYP NYT+
Sbjct: 1582 YYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTS 1641
Query: 1649 GQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLAT 1708
GQICLY +TVPK++VVFGQFA+F TALND+ E+ DG +RLLSSLSGSH+GE+LPLAT
Sbjct: 1642 GQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLAT 1701
Query: 1709 SNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFEC 1768
SNQ+L++FSAK A ARGFHFVYQAVPRTS TQCSSVPEPRYG+R+GS+FS G+IVRFEC
Sbjct: 1702 SNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFEC 1761
Query: 1769 NPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLN 1828
N GY LQGS + C VP ALAQWN + P+CVVPC GN T+RRGTILSPG+PEPY N+LN
Sbjct: 1762 NSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLN 1821
Query: 1829 CIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQ 1888
C+WKI+V EG+GIQIQV+SF TEQNWDSLE+ DG D T LGSFSGTTVPALLNSTSNQ
Sbjct: 1822 CVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQ 1881
Query: 1889 LYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTL 1948
LYLHF SDISV+AAGFHLEYKTVGL++C EPA+PSN +K G+RY+VNDV+SFQCEPGY L
Sbjct: 1882 LYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYAL 1941
Query: 1949 QGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLP 2008
QG +HISCMPGTVRRWNYP PLCIA CGGT+ + GVILSPGFPG+YP+N+DC+W+I+LP
Sbjct: 1942 QGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALP 2001
Query: 2009 IGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSD 2068
+G+GAHIQFLNFSTE NHD++EI+NGPY TS M+G+FSG++LP++LLST+HET ++F+SD
Sbjct: 2002 VGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSD 2061
Query: 2069 HSQNRQGFKLAYQ------------------------------------------AYELQ 2086
HSQNR GFKL YQ AYELQ
Sbjct: 2062 HSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQ 2121
Query: 2087 NCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAP 2146
CPDP PF NG + + Y+VGQSV+FEC PGY L GHPVLTCQHG NRNW++P P+C+ P
Sbjct: 2122 ECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVP 2181
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
CG N+TS NGT+YSPGFP Y +DC+WLITVP GHGV +N +LLQTE D+I +WDG
Sbjct: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDG 2241
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVP 2266
P Q +P+LGVF+ + A +T SS+NQVLLKFH D + GG F + F A+ L KC PP +P
Sbjct: 2242 PQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILP 2301
Query: 2267 QAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
AE++TE+++F IGD V+Y+C PG+TLVG +ILTCKL + LQFEG P CE CP NE+
Sbjct: 2302 NAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELL 2361
Query: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQS 2386
T S+GVILS YPG+Y QTCSW ++VEP+YNI++ V+ F SEKQ+D E+FDG SGQS
Sbjct: 2362 TDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQS 2421
Query: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILN 2446
PLL LSGN++ TS SN +YLRWS+DHA ++KGFKIRY+APYCSL +G IL
Sbjct: 2422 PLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILG 2481
Query: 2447 RTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGS 2506
+T+ G +H+ C GYR+VGHS A C R+P G + W PLCQA+SCG+PE+P NG
Sbjct: 2482 QTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGM 2541
Query: 2507 FTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLS 2566
G E+T+ +K +Y C EG+ L++ +ATA C + GLWSN+ PP C PV CP + +
Sbjct: 2542 VFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISV 2601
Query: 2567 EHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSL 2626
EH WRL+ + ++ AQ++L C PGYY G R++RCQANG W++GD P+CR+ISCG L
Sbjct: 2602 EHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGEL 2661
Query: 2627 SFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDP 2686
PPNG++IGTL+VYGATAIF+CN+GYTLVGS VREC+ANGLWSGSE RCLAGHCG+P+P
Sbjct: 2662 PIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEP 2721
Query: 2687 IVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPA 2746
IVNGHI+G+ +SYR +VVYQCN GFRL+G SVRIC QDH WSG+TP CV ++CGHPG+P
Sbjct: 2722 IVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPP 2781
Query: 2747 HGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC---RVVNCSDPGFV 2803
H +G + + VV ++C L G S C +G W+ LP C V C DPG
Sbjct: 2782 HSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIP 2841
Query: 2804 ENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHP 2863
+ IR G +SF+ G + + C+ G L GSS TC ANG W S P+C ISCG+P
Sbjct: 2842 AHGIRLG-----DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNP 2896
Query: 2864 GVPANA-VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCG 2922
G P+NA V+ + + + + Y CR G +R C + W+G+ P C N CG
Sbjct: 2897 GTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN---CG 2953
Query: 2923 DPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGS--PERTCLLNGSWSGLQPVCEAVSCG 2980
DPG PA+G RLG+DF+ + + C G+ + +C + +W+G +PVC+A+ C
Sbjct: 2954 DPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCK 3013
Query: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGD 3040
P NG +V SD ++ SSV YAC EGY+ S C NG+WTG P C + CGD
Sbjct: 3014 PPPLIPNGKVVGSD-FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGD 3072
Query: 3041 PGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVC---KAVL 3097
PG + G + F++ +VS+ C+P V+ V S C DG W+ ++P C
Sbjct: 3073 PGVPSRGRREDRGFSYRSSVSFSCHPPLVL--VGSPRRFCQSDGTWSGTQPSCIDPTLTT 3130
Query: 3098 CPQPPPVQNGTVEGSD-FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFC 3156
C P Q G S ++ GS++ + C GY L S +C W G P C+P C
Sbjct: 3131 CADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHC 3190
Query: 3157 GDPGIPAE---GRLSGKSFTYKSEVFFQCKSPFILV-GSSRRVCQADGTWSGIQPTCID 3211
P P G L S Y + + C+ F L GS R C+ADG+W+G P C++
Sbjct: 3191 RQPETPTHANVGALDLPSMGY--TLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
Score = 1464 bits (3789), Expect = 0.0
Identities = 987/3077 (32%), Positives = 1449/3077 (47%), Gaps = 230/3077 (7%)
Query: 403 HRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER 462
H P + C L GP+G + SP +P Y + A+C W IT + + I+L F+ F LE
Sbjct: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHR-IQLVFQSFALEE 75
Query: 463 GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQE 522
+D L+V D ++ LTG +P IVS + + L L SD ++ + GF A Y+
Sbjct: 76 DFDVLSVFDGPP--QPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEV 133
Query: 523 IEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ----WSGNK 578
+ CG+PG G + GS+F GD + + C F L G V+TC ++ W
Sbjct: 134 LPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPL 193
Query: 579 PSCVF--SCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQF 636
PSC +C SGII SP++P EY NN +C W I++E G I L+F DF +E +
Sbjct: 194 PSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGY 253
Query: 637 DFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY------ 690
DFL V S + F+G +P+ + SS + +RL F SD + RGF+ Y
Sbjct: 254 DFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQI 309
Query: 691 --------------------------TTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHC 724
+ G N C DPGIP G+R G F LGSSV F C
Sbjct: 310 ELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTC 369
Query: 725 DDGFVKTQGSESITCI-LQDGNVVWSSTVPRCEA-PCGGHLTASSGVILPPGWPGYYKDS 782
++G+ QGS+ ITC+ + D WS P C A C HL SG+I P +P Y ++
Sbjct: 370 NEGY-DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNN 428
Query: 783 LHCEWIIEA-KPGHSIKITFDRFQTEVNYDTLEVRDG--PASSSPLIGEYHGTQAPQFLI 839
HC WII A P IK+ F+ F E YDTL V DG ++ GT P ++
Sbjct: 429 AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
Query: 840 STGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFS 899
ST + M+LLF TD S SS+GF YE + E SC DPGIP G R G F T+ F
Sbjct: 489 STNHQMWLLFQTDGSGSSLGFKASYEEI--EQGSCGDPGIPAYGRREGSRFHHGDTLKFE 546
Query: 900 CDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTW 959
C P + L + + C++N+QW+ P C C SG VLSP +P+ Y N L+C W
Sbjct: 547 CQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVW 606
Query: 960 TIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFT 1018
I + + F+ +E D+L+I + + PV +G+ LP +I +
Sbjct: 607 LILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITS---SGHV 663
Query: 1019 AQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGY-R 1077
A+L F +D S GFNITF+ + C DPGVP +R G +G S++F C G+
Sbjct: 664 ARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLG 723
Query: 1078 LEGATKLTC-LGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIE 1136
+G+ +TC L G VW++ + RC A CG + GT+LSP +P Y + C + IE
Sbjct: 724 TQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
Query: 1137 TEAGKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEF 1195
+ G I + F+ DTL+V DG+ S+ +G + ++ ++ STSN+L+L F
Sbjct: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLI-STSNYLYLLF 842
Query: 1196 NTNGSDTDQGFQLTYTSFDLVK--CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHG 1253
+T+ S +D GFQL Y + L C DPGIP G R + +V +SC+ GY +
Sbjct: 843 STDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR-HGNDFYVGALVTFSCDSGYTLSD 901
Query: 1254 SNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADP 1313
L C + W + LPSC A CGG I +SG ILSPG+P Y NNL+CTWIIE
Sbjct: 902 GEPLECEPNFQ--WSRALPSCEALCGGFIQ-GSSGTILSPGFPDFYPNNLNCTWIIETSH 958
Query: 1314 GKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHS-TFNSLTLQ--FD 1370
GK + F F E HD L + + + L++ +GS LP I + + + T Q F
Sbjct: 959 GKGVFFTFHTFHLESGHDYLLITENGSFTQ-PLRQLTGSRLPAPISAGLYGNFTAQVRFI 1017
Query: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKI 1430
SDF +S GF+I FS C +P +P R G GDT+TF C PGY+L+G A+I
Sbjct: 1018 SDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARI 1077
Query: 1431 TCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVI 1490
TC+ R W P C+A CG ++TG G +LSPN+P Y EC + ++ P I
Sbjct: 1078 TCLG-GRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
Query: 1491 ALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQ-APERIESSGNSLFLAFRSDASVG 1549
L ++F + D L +Y+G ++++ L+G + S+ + S+ +SL+L F +DA
Sbjct: 1137 QLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
Query: 1550 LSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKL-GSTITYQCDSGYKILDPSSITCVIG 1608
GF + F C DPG G +V + GS++++ CD GY + + C+ G
Sbjct: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
Query: 1609 ADGKPSWDQVLPSCNAPCGGQYTGS-EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQ 1667
+ +WD+ LP+C A CGG G G VLSP YP Y C+++I +
Sbjct: 1256 E--RRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLH 1313
Query: 1668 FAYFQT-ALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARG 1726
F F T ++D+ ++DG LL LSG + L +T N ++L+FS S +G
Sbjct: 1314 FLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLH-STFNSVVLQFSTDFFTSKQG 1372
Query: 1727 FHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVP 1786
F + ++ T C+ P+ G R G + AG F+C+PGY LQGS + C +
Sbjct: 1373 FAIQFSV---STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIE 1429
Query: 1787 NALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVI 1846
N W + P+C+ PC G+ T G ILSP YPEPY C WK+ V+ I +
Sbjct: 1430 NRFF-WQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFN 1488
Query: 1847 SFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHL 1906
F E +D L I+DG D +P +GSF G+ +P + S+SN L+L F+SD SV+ AGF +
Sbjct: 1489 IFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVI 1548
Query: 1907 EYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRR--W 1964
+Y +C +P N ++G + +++ C GY ++G S +SC+ G + W
Sbjct: 1549 DYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVW 1608
Query: 1965 NYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEA 2024
N P P+C A CGG GV+LSP +P +Y + C + +++P Y QF F T
Sbjct: 1609 NNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTAL 1668
Query: 2025 NHDFLEIQNGPYHTSPMIGQFSGTDLPAAL-LSTTHETLIHFYSDHSQNRQGFKLAYQAY 2083
N D +E+ +G S ++ SG+ +L L+T+++ LI F + +GF YQA
Sbjct: 1669 N-DVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAV 1727
Query: 2084 ---ELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTC--QHGINRNWNY 2138
C P + G + SD+SVG V FEC GY L G P + C G WN
Sbjct: 1728 PRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNV 1787
Query: 2139 PFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN 2198
P C PCG N+T + GTI SPGFP+ Y +C+W I VP G G+ I TE
Sbjct: 1788 SAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNW 1847
Query: 2199 DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLK 2257
D + V+DG D LG FSG T S++NQ+ L F+SD S + F L + L
Sbjct: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
C P PAVP + T + + + D V +QC PGY L G ++C + ++ P C
Sbjct: 1908 SC-PEPAVPSNGVKT-GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
Query: 2318 AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALE 2377
AQC GVILSPG+PGNY ++ CSW I + + I F +E D +E
Sbjct: 1966 AQCGGTVEE--MEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIE 2023
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTH 2437
+ +G S ++ SG+ S+ S S++ + + +DH+ ++ GFK+ Y LT+
Sbjct: 2024 IRNGPYETSRMMGRFSGSEL-PSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ----DLTY 2078
Query: 2438 PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV--- 2494
+ L G+ + Y WD L P C+A
Sbjct: 2079 SHQISSFLR----------------GFDLSELERTNSTPPVAASYVWD-LDPGCEAYELQ 2121
Query: 2495 SCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKP-PTC 2553
C PE NG G + + V +EC G++L T CQ G N P P C
Sbjct: 2122 ECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLT--CQH-GTNRNWDHPLPKC 2178
Query: 2554 KPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLE-GWRLLRCQANGTWNIG 2612
+ +I + S + L++ G+ + LL+ + +G +
Sbjct: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI 2238
Query: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGS 2672
+ P ++G T A ++ L+ H R+ G+++ +
Sbjct: 2239 WDGPQ------------QTAPRLGVFTRSMAKKTVQSSSNQVLLKFH-RDAATGGIFAIA 2285
Query: 2673 ETRCLAGHCGSPDPIVNGHI--SGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDH--KWS 2728
+ C P + N + + F+ D V Y+C PGF LVG + C ++
Sbjct: 2286 FSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFE 2345
Query: 2729 GQTPVC---------------VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLL-- 2771
G P+C V ++ +PG+ T + N + Y L
Sbjct: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
Query: 2772 ------------QGVSRAQCRSNGQWSSPLPTCRVVN------CSDPGF----------- 2802
G S +G +S+PL N SD +
Sbjct: 2406 KQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Query: 2803 ----VENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMAN----GLWDRSLPK 2854
+ A HG S + G SI + C G+ L+G S C + LW ++P
Sbjct: 2466 PYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
Query: 2855 CLAISCGHPGVPANAVLTGELFTYGAVVHYSC-RGSESLIGND-TRVCQEDSHWS--GAL 2910
C A+SCG P P N ++ G+ +T G YSC G G + T C + WS
Sbjct: 2526 CQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP 2585
Query: 2911 PHCTGNNPGFCGDPGTPA--HGS-RL--GDDFKTKSLLRFSCEMGHQLRGSPERTCLLNG 2965
P C P C D + + HG RL ++ ++ L C+ G+ G C NG
Sbjct: 2586 PQCV---PVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2642
Query: 2966 SWS--GLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN 3023
WS P C +SCG P NG + + + + ++ I++C GY G R C AN
Sbjct: 2643 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV-YGATAIFSCNSGYTLVGSRVRECMAN 2701
Query: 3024 GTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKD 3083
G W+G+ C CG P + NG G ++++ +V YQCN G+ + + C +D
Sbjct: 2702 GLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGF--RLIGMSVRICQQD 2759
Query: 3084 GRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGV 3143
W+ P C V C P + + G + G+ + YSC+ L ++ C G
Sbjct: 2760 HHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGH 2819
Query: 3144 WKGEIPQCLPV---FCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADG 3200
W G +P C CGDPGIPA G G SF + + F C++ +L GSS R CQA+G
Sbjct: 2820 WTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANG 2879
Query: 3201 TWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLA 3260
+WSG QP C +C +PGTP S G S++ + CR+GY+ G +R C
Sbjct: 2880 SWSGSQPEC---GVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSV 2936
Query: 3261 NLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHR---- 3316
N TW+G EC+ C P PA+ +R + + T+ Y C PG+ + HR
Sbjct: 2937 NGTWTGSDPECLVINCGDPGIPANG-LRLGNDFRYNKTVTYQCVPGYMM---ESHRVSVL 2992
Query: 3317 TCKADMKWTGKSPVCKS 3333
+C D W G PVCK+
Sbjct: 2993 SCTKDRTWNGTKPVCKA 3009
Score = 1395 bits (3610), Expect = 0.0
Identities = 947/3039 (31%), Positives = 1423/3039 (46%), Gaps = 273/3039 (8%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
+ + C ++GP+G I SP FP Y N A+C WII ++ I+L+F F LE +D L
Sbjct: 401 RARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTL 460
Query: 87 SVYDGQPQQGNLKV---RLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSH 143
+V DG Q G+ K L+G +P IVST + L F TD + S+ GFKA YE +
Sbjct: 461 TVGDG-GQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQG 519
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+CG+PG G G+RF+ GD +++ C P + L G +TC W P C
Sbjct: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC----QKNNQWSAKKPGC- 574
Query: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
+C S + SP++P +Y N+ C W ILA P I L F D +E +DFL
Sbjct: 575 -VFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLV 633
Query: 264 I---SGTEAPSI-WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319
I + EAP + +G LPS + SS + RL F +D + ++GFN F + E
Sbjct: 634 IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE--- 690
Query: 320 RGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDN 379
CPDPG+P NG+R G D ++G+++ F C++
Sbjct: 691 -----------------------------CPDPGVPVNGKRFG-DSLQLGSSISFLCDEG 720
Query: 380 YV-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHC 438
++ QGS++ITC + E W+ C A CG +L PSG I SP +P Y+D C
Sbjct: 721 FLGTQGSETITCV-LKEGSVVWNSAVLRCEA-PCGGHLTSPSGTILSPGWPGFYKDALSC 778
Query: 439 VWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS--VLYVLTGSSVPDLIVS 496
WVI P IK+ F+ F+ E YDTL V D G T S ++ V G+ VP ++S
Sbjct: 779 AWVI-EAQPGYPIKITFDRFKTEVNYDTLEVRD----GRTYSAPLIGVYHGTQVPQFLIS 833
Query: 497 MSNQMWLHLQSDDSIGSPGFKAVYQEI--EKGGCGDPGIPAYGKRTGSSFLHGDTLTFEC 554
SN ++L +D S GF+ Y+ I + C DPGIP G+R G+ F G +TF C
Sbjct: 834 TSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSC 893
Query: 555 PAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWL 614
+ + L + C+ N QWS PSC C SSG ILSP +P+ Y NN+NC W+
Sbjct: 894 DSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWI 953
Query: 615 IISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIV 671
I + G + F+ F +E D+L + ++G S L +G+ +P+ +++
Sbjct: 954 IETSHGKGVFFTFHTFHLESGHDYLLITENG-SFTQPLRQLTGSRLPAPISAGLYGNFTA 1012
Query: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
++ F SD S + GFNIT++ + C +P +P R G +F +G +++F C G+ +
Sbjct: 1013 QVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGY-RL 1071
Query: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
+G+ ITC L +WSS +PRC A CG +T + G +L P +P Y ++ C + I+
Sbjct: 1072 EGTARITC-LGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQT 1130
Query: 792 KPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEY-HGTQAPQFLISTGNFMYLLFT 850
+PG I++ F+ D L+V DG +S+ L+G + H L ST + ++L F
Sbjct: 1131 QPGKGIQLKARAFELSEG-DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFI 1189
Query: 851 TDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHR-HGGDFGIRSTVTFSCDPGYTLSDD 909
TD +S GF +H+ S E C DPG P G++ H S+V+FSCDPGY+L
Sbjct: 1190 TDAENTSKGFELHFSS--FELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGS 1247
Query: 910 EPLVC--ERNHQWNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHG 966
E L+C W+ LP+C A CGG ++G+ SG VLSPG+P Y ++LNC WTIE G
Sbjct: 1248 EELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1307
Query: 967 KGVQMIFHTFHLESSHDYLLITEDGSFSEPV--ARLTGSVLPHTIKAGLFGNFTAQLRFI 1024
+ + F F E HD L I DG V L+G LP + + + L+F
Sbjct: 1308 CTIGLHFLVFDTEEVHDVLRIW-DGPVESGVLLKELSGPALPKDLHSTF---NSVVLQFS 1363
Query: 1025 SDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKL 1084
+DF S +GF I FS C+DPG+P R G + GDS F C GY L+G+ ++
Sbjct: 1364 TDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEI 1423
Query: 1085 TCLG-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGI 1143
+C+ R W P C+A CG + G G +LSPN+P Y EC +K+ I
Sbjct: 1424 SCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483
Query: 1144 HLRTRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDT 1202
L F L G D L +YDG+DS S +G+F ++L G I S+SN L+L F ++ S +
Sbjct: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRI-ESSSNSLFLAFRSDASVS 1542
Query: 1203 DQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSG 1262
+ GF + YT C DPG G R+ + +V Y C+ GY + G++TL+C+ G
Sbjct: 1543 NAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYY-CHGGYEVEGTSTLSCILG 1601
Query: 1263 --DRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLH 1320
+ VW+ P P C A CGGQ + + G +LSP YP Y + C + + +
Sbjct: 1602 PDGKPVWNNPRPVCTAPCGGQ-YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQ 1660
Query: 1321 FIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSG 1379
F F T + +D+++V DG LL SGS E + +T N + ++F + G
Sbjct: 1661 FAFFHTAL-NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARG 1719
Query: 1380 FSIQFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLN 1436
F + + A C+ P+ G R G G V F+C+ GY LQG +I C+ +
Sbjct: 1720 FHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
Query: 1437 NRFF-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFK 1495
W PTC+ CGGNLT G ILSP +P+PY C W++ V I +
Sbjct: 1780 GALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVV 1839
Query: 1496 SFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAI 1555
SF E ++D L +++G D+ ++GS+ G+ P + S+ N L+L F SD SV +GF +
Sbjct: 1840 SFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHL 1899
Query: 1556 EFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSW 1615
E+K +C +P NG + G + + +++QC+ GY + + I+C+ G + W
Sbjct: 1900 EYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRR--W 1957
Query: 1616 DQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTAL 1675
+ P C A CGG EGV+LSP +P NY + C + I +P F QF F T
Sbjct: 1958 NYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEP 2017
Query: 1676 N-DLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQ-- 1732
N D E+ +G + +R++ SGS +L L+TS++ + F + + GF YQ
Sbjct: 2018 NHDYIEIRNGPYETSRMMGRFSGSELPSSL-LSTSHETTVYFHSDHSQNRPGFKLEYQDL 2076
Query: 1733 ----------------AVPRTSDT------------------QCSSVPEPR---YGRRIG 1755
+ RT+ T + P+P G G
Sbjct: 2077 TYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRG 2136
Query: 1756 SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTIL 1815
+ ++ G V FEC PGY L G L CQ N W+ +P C VPC GN T GT+
Sbjct: 2137 AGYNVGQSVTFECLPGYQLTGHPVLTCQHGTN--RNWDHPLPKCEVPCGGNITSSNGTVY 2194
Query: 1816 SPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSG 1875
SPG+P PY ++ +C+W I V G G+++ + TE + D + I DG TAPRLG F+
Sbjct: 2195 SPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTR 2254
Query: 1876 TTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNS--IKIGDRYM 1933
+ + S+SNQ+ L F D + F + + L C P + N+ + + +
Sbjct: 2255 SMAKKTVQSSSNQVLLKFHRDAATGGI-FAIAFSAYPLTKCPPPTILPNAEVVTENEEFN 2313
Query: 1934 VNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC--GGTLSTLGGVILSPGF 1991
+ D++ ++C PG+TL G ++C GT ++ P P+C C L+ GVILS +
Sbjct: 2314 IGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSY 2373
Query: 1992 PGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGT-DL 2050
PGSYP C+W + + Y + F +E +D EI +GP SP++ SG
Sbjct: 2374 PGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSA 2433
Query: 2051 PAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI-NSDYSVGQS 2109
P + S+++ + + SDH+ NR+GFK+ Y A C P +G+++ + G S
Sbjct: 2434 PLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLPRAPLHGFILGQTSTQPGGS 2490
Query: 2110 VSFECYPGYILIGHPVLTC-QHGINRN-WNYPFPRCDA-PCGYNVTSQNGTIYSPGFPDE 2166
+ F C GY L+GH + C +H + W+ P C A CG +NG ++ +
Sbjct: 2491 IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVG 2550
Query: 2167 YPILKDC---IWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTAL 2223
+ C L ++ L V PD +S +
Sbjct: 2551 TKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIF 2610
Query: 2224 ETAYSSTNQVLLKFHSDFSNGGFFVLNFHA------------FQLKKCQPPPAVPQAEML 2271
ET Y Q++L + G V+ A ++ C P P +
Sbjct: 2611 ETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRI 2670
Query: 2272 TEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSG 2331
+ G + C+ GYTLVG+ + C + G E +C A T
Sbjct: 2671 GTLSVY--GATAIFSCNSGYTLVGSRVRECMAN------GLWSGSEVRCLAGHCGTPEPI 2722
Query: 2332 VILSPGYPGNYFNSQTCSWSIKVEPNYN-----ITIFVDTFQSEKQFDALEVFDGSSGQS 2386
V + N + S+ V N I + V Q + + SG++
Sbjct: 2723 V-------NGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHW---------SGKT 2766
Query: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILN 2446
P V++S H + S Y
Sbjct: 2767 PFCVLVSCGHPGSPPHSQMSGDSY------------------------------------ 2790
Query: 2447 RTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS---CGIPESPG 2503
VG+ V Y C +VG+S C + W P C S CG P P
Sbjct: 2791 ----TVGAVVRYSCIGKRTLVGNSTRMCGLDG----HWTGSLPHCSGTSVGVCGDPGIPA 2842
Query: 2504 NGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEA 2563
+G G+ F + + + C G L S + T CQ +G WS G P C ++C +
Sbjct: 2843 HGIRLGDSFDPGTVMRFSCEAGHVLRGSSERT--CQANGSWS--GSQPECGVISCGNPGT 2898
Query: 2564 QLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISC 2623
+ V++ S L + + ++ C GYY G C NGTW D P C VI+C
Sbjct: 2899 PSNARVVF---SDGL-VFSSSIVYECREGYYATGLLSRHCSVNGTWTGSD--PECLVINC 2952
Query: 2624 GSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSH---VRECLANGLWSGSETRCLAGH 2680
G P NG ++G Y T + C GY ++ SH V C + W+G++ C A
Sbjct: 2953 GDPGIPANGLRLGNDFRYNKTVTYQCVPGY-MMESHRVSVLSCTKDRTWNGTKPVCKALM 3011
Query: 2681 CGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCG 2740
C P I NG + G F + +V Y C G++L +V C + W+G+ P C P+ CG
Sbjct: 3012 CKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
Query: 2741 HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC---RVVNC 2797
PG P+ G F+ V+F+C+ +L G R C+S+G WS P+C + C
Sbjct: 3072 DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTC 3131
Query: 2798 SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLA 2857
+DPG + G QN + ++ G ++L+ C+KG+ L GS+ TC+ N W + P C+
Sbjct: 3132 ADPGVPQ----FGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVP 3187
Query: 2858 ISCGHPGVPANA-VLTGELFTYGAVVHYSCRGSESLI-GNDTRVCQEDSHWSGALPHCTG 2915
C P P +A V +L + G + YSC+ SL G++ R C+ D W+G P C
Sbjct: 3188 HHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
Query: 2916 NNPGFCGDPGTPAHGSRL------GDDFKTKSLLRFSCE 2948
P G P A L GD F SL + + E
Sbjct: 3248 VRPS--GRPINTAREPPLTQALIPGDVFAKNSLWKGAYE 3284
Score = 1057 bits (2733), Expect = 0.0
Identities = 503/1007 (49%), Positives = 653/1007 (64%), Gaps = 30/1007 (2%)
Query: 2582 GAQVLLSCSPGYYLEGWRLLRC----QANGTWNIGDERPSCRVISCGSLSFPPNGNKIGT 2637
G + C+ GY L G + C Q W+ + P C+ +SCG P NG G
Sbjct: 2488 GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS--EAIPLCQALSCGLPEAPKNGMVFGK 2545
Query: 2638 LTVYGATAIFTCNTGYTLVGSH--VRECLANGLWSGSET--RCLAGHCGSPDPIVNGH-- 2691
G A+++C+ GY L ECL GLWS +C+ C I H
Sbjct: 2546 EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGR 2605
Query: 2692 ---ISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWS--GQTPVCVPITCGHPGNPA 2746
I + ++ ++ C+PG+ G V C + KWS TP C I+CG P
Sbjct: 2606 WRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPP 2665
Query: 2747 HGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA 2806
+G G+ F+CN+GY L G +C +NG WS C +C P + N
Sbjct: 2666 NGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNG 2725
Query: 2807 IRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVP 2866
+G E++ Y S++Y C GF L+G S C + W P C+ +SCGHPG P
Sbjct: 2726 HING-----ENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSP 2780
Query: 2867 ANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGT 2926
++ ++G+ +T GAVV YSC G +L+GN TR+C D HW+G+LPHC+G + G CGDPG
Sbjct: 2781 PHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGI 2840
Query: 2927 PAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPT 2986
PAHG RLGD F +++RFSCE GH LRGS ERTC NGSWSG QP C +SCGNPGTP+
Sbjct: 2841 PAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPS 2900
Query: 2987 NGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLAN 3046
N +V SDG++FSSS++Y C EGY +GL++RHC+ NGTWTG+ P+C +I+CGDPG AN
Sbjct: 2901 NARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPAN 2960
Query: 3047 GIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQN 3106
G++ G DF +NKTV+YQC PGY+ME+ + + CTKD WN +KPVCKA++C PP + N
Sbjct: 2961 GLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPN 3020
Query: 3107 GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGR 3166
G V GSDF WGSS++Y+C++GYQLS A+ +CEG G W GE+PQC PVFCGDPG+P+ GR
Sbjct: 3021 GKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR 3080
Query: 3167 LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFG 3226
+ F+Y+S V F C P +LVGS RR CQ+DGTWSG QP+CIDP TC DPG P FG
Sbjct: 3081 REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFG 3140
Query: 3227 IQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHAD 3286
IQN+S+GY+VGSTV FRC+KGY +QGSTTRTCL NLTWSG +C+PH CRQPETP HA+
Sbjct: 3141 IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHAN 3200
Query: 3287 VRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC-----KSKGVREVNE 3341
V A+DLP+ GYTL+Y+C GF L GGSEHRTCKAD WTGK P+C + + E
Sbjct: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTARE 3260
Query: 3342 -TVTKTPVPSDVFFVNSLWKGYYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKL 3400
+T+ +P DVF NSLWKG YEY GK+QPA L V F +SKVNAT + S VEL L
Sbjct: 3261 PPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHSGVELHL 3320
Query: 3401 TGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDF 3460
G YKKE+ HLLL+ +QI G +IF++KF++D+W LDG+VSS F +QG + G+ F
Sbjct: 3321 AGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGSVKGQGF 3380
Query: 3461 GKFKLERQD--PLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKV 3518
G+F +R D L D +S + ++S SVAAAILVPF ALI++GF YLYKHR RPKV
Sbjct: 3381 GQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKV 3440
Query: 3519 QYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFDTTLNTVCTVV 3565
+NGYAGHEN+N +A+FENPMYD N++PT+ A + T++TVCT V
Sbjct: 3441 PFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV 3487
Score = 966 bits (2496), Expect = 0.0
Identities = 740/2443 (30%), Positives = 1094/2443 (44%), Gaps = 227/2443 (9%)
Query: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
+H S C + G +GTV SPGFP YPN NCTWTI +Q++F +F LE
Sbjct: 16 SHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE 75
Query: 981 SHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
D L + + E + RLTG LP TI + T LR ISD+++S +GF+ T+
Sbjct: 76 DFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAA---TTLSLRLISDYAVSAQGFHATYE 132
Query: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRR--VWSAP 1097
C +PG + G F +GD + +SC LG+ LEG LTC G W P
Sbjct: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
Query: 1098 LPRCVAE--CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
LP C A+ CG +++G G + SP+FPS Y NN +C + I E G I L FQL +G
Sbjct: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
Query: 1156 DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDL 1215
G + SS FT L ++ S+ N L L F ++G+ +GF Y
Sbjct: 253 YDFLEVTGTEGSSL---WFTGASLPAPVI-SSKNWLRLHFTSDGNHRQRGFSAQYQVKKQ 308
Query: 1216 VK--------------------------------CEDPGIPNYGYRIRDEGHFTDTVVLY 1243
++ C DPGIP G R+ + + V +
Sbjct: 309 IELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSS-VQF 367
Query: 1244 SCNPGYAMHGSNTLTCL--SGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDN 1301
+CN GY + GS +TC+ S W P C A SG I SP +P YDN
Sbjct: 368 TCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDN 427
Query: 1302 NLHCTWIIEA-DPGKTISLHFIVFDTEMAHDILKVWDGPVDSD--ILLKEWSGSALPEDI 1358
N HC WII A +P K I L F FD E +D L V DG D D +L +G+++P+ I
Sbjct: 428 NAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLI 487
Query: 1359 HSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQC 1418
ST + + L F +D S GF + +C DPG+P G R G GDT+ F+C
Sbjct: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFEC 547
Query: 1419 DPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKEC 1478
P ++L GQ ITC Q NN+ W P C+ +C N T P+GV+LSPNYP+ Y C
Sbjct: 548 QPAFELVGQKAITC-QKNNQ--WSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHC 604
Query: 1479 DWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSL 1538
W + P+ I L F ++EP +DFL I +G + +P++G++ G+Q P I SSG+
Sbjct: 605 VWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVA 664
Query: 1539 FLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKIL 1598
L F++D S G GF I F C DPG +NG R G +LGS+I++ CD G+
Sbjct: 665 RLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGT 724
Query: 1599 DPS-SITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSIT 1657
S +ITCV+ +G W+ + C APCGG T G +LSP +P Y C + I
Sbjct: 725 QGSETITCVL-KEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIE 783
Query: 1658 VPKEFVVFGQFAYFQTALN-DLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRF 1716
+ + F F+T +N D E+ DG A L+ G+ + L ++TSN + L F
Sbjct: 784 AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFL-ISTSNYLYLLF 842
Query: 1717 SAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQG 1776
S S GF Y+ + SD C P G+R G++F G++V F C+ GY L
Sbjct: 843 STDKSHSDIGFQLRYETITLQSD-HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSD 901
Query: 1777 STALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVT 1836
L C+ PN QW+ +PSC C G GTILSPG+P+ Y NNLNC W I +
Sbjct: 902 GEPLECE--PN--FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETS 957
Query: 1837 EGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNS---TSNQLYLHF 1893
G G+ +F E D L I + G T P L +G+ +PA +++ + + F
Sbjct: 958 HGKGVFFTFHTFHLESGHDYLLITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRF 1016
Query: 1894 QSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSH 1953
SD S++ GF++ + L C+EP +P+ SI+ G ++ V D L+F C PGY L+G +
Sbjct: 1017 ISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTAR 1076
Query: 1954 ISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGA 2013
I+C+ G R W+ P P C+A CG +++ G +LSP FP +Y NN +C + I G G
Sbjct: 1077 ITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGI 1136
Query: 2014 HIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETL-IHFYSDHSQN 2072
++ F + D L++ +G +++ ++G FS +++ L++T +L + F +D
Sbjct: 1137 QLKARAFEL-SEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENT 1195
Query: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINSD-YSVGQSVSFECYPGYILIGHPVLTCQHG 2131
+GF+L + ++EL C DP + GY ++ + + G SVSF C PGY L G L C G
Sbjct: 1196 SKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSG 1255
Query: 2132 INRNWNYPFPRCDAPCGYNVTSQ-NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFT 2190
R W+ P P C A CG V + +G + SPG+P Y +CIW I G + ++F
Sbjct: 1256 ERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFL 1315
Query: 2191 LLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD-FSNGGFFVL 2249
+ TE V+D + +WDGP ++ L SG + +S+ N V+L+F +D F++ F +
Sbjct: 1316 VFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAI 1375
Query: 2250 NFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTC-KLSSQLQ 2308
F C P +PQ D +E GD +QC PGY L G+ ++C K+ ++
Sbjct: 1376 QFSVSTATSCN-DPGIPQ-NGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFF 1433
Query: 2309 FEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQ 2368
++ S PTC A C + TG SGVILSP YP Y + C W + V P+Y I + + F
Sbjct: 1434 WQPSPPTCIAPCGGD--LTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFN 1491
Query: 2369 SEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2428
E +D L ++DG SPL+ G+ S SN L+L + +D + S GF I Y
Sbjct: 1492 LEPGYDFLHIYDGRDSLSPLIGSFYGSQL-PGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
Query: 2429 AA-PYCSLTHP--LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWD 2485
P S P +KNG + +GS V Y+C GY + G S +C P G W+
Sbjct: 1551 TENPRESCFDPGSIKNGTRVGSDL-KLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWN 1609
Query: 2486 SLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWS 2545
+ P+C A P G + G++ VV + S Q +
Sbjct: 1610 NPRPVCTA--------PCGGQYVGSD-----GVVLSPNYPQNYTSGQICLYFVTVPKDYV 1656
Query: 2546 NKGKPPTCKPVACPSIEAQLSEHVIWRLVSG-SLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2604
G+ +E RL+S S + G + L+ S ++
Sbjct: 1657 VFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAP 1716
Query: 2605 ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECL 2664
A G + P C S+ P G ++G+ GA F CN+GY L GS ECL
Sbjct: 1717 ARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECL 1776
Query: 2665 ----ANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLV---GTS 2717
A W+ S C+ CG G I GF + + N +++V G
Sbjct: 1777 PVPGALAQWNVSAPTCVV-PCGGNLTERRGTILSPGFP--EPYLNSLNCVWKIVVPEGAG 1833
Query: 2718 VRI----CLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG 2773
++I + + W + + G N + S + ++N T N Y L
Sbjct: 1834 IQIQVVSFVTEQNWDS-----LEVFDG-ADNTVTMLGSFSGTTVPALLNSTSNQLY-LHF 1886
Query: 2774 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFY 2833
S + G + T + +C +P N ++ G E + + + C+ G+
Sbjct: 1887 YSDISVSAAG-FHLEYKTVGLSSCPEPAVPSNGVKTG-----ERYLVNDVVSFQCEPGYA 1940
Query: 2834 LLGSSALTCMANGL--WDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSES 2891
L G + ++CM + W+ P C+A CG V+ F + C
Sbjct: 1941 LQGHAHISCMPGTVRRWNYPPPLCIA-QCGGTVEEMEGVILSPGFPGNYPSNMDC----- 1994
Query: 2892 LIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGH 2951
W ALP G AH L FS E H
Sbjct: 1995 -------------SWKIALP------------VGFGAH----------IQFLNFSTEPNH 2019
Query: 2952 ---QLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGT---------PTNGMIVSSDGILFS 2999
++R P T + G +SG + +S + T G + + +S
Sbjct: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYS 2079
Query: 3000 SSVIYACWEGYKTSGLMTRHCT----ANGTWTGTAPDC---TIISCGDPGTLANGIQFGT 3052
I + G+ S L + T A+ W P C + C DP ANGI G
Sbjct: 2080 HQ-ISSFLRGFDLSELERTNSTPPVAASYVW-DLDPGCEAYELQECPDPEPFANGIVRGA 2137
Query: 3053 DFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGS 3112
+ ++V+++C PGY + T + + W+ P C+ V C NGTV
Sbjct: 2138 GYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNITSSNGTVYSP 2196
Query: 3113 DFRWGSSISYSCM--------DGYQLSHSAILSCEGRG----VWKGEIPQCLPVFCGDPG 3160
F S S C+ G +L+ S +L E G +W G PQ G
Sbjct: 2197 GFPSPYSSSQDCVWLITVPIGHGVRLNLS-LLQTEPSGDFITIWDG--PQQTAPRLG--- 2250
Query: 3161 IPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVC---QADGTWSGIQPTCIDPAHNT- 3216
VF + + + SS +V D GI T
Sbjct: 2251 -----------------VFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2293
Query: 3217 CPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC 3258
CP P P+ + + + +G V +RC G+ + G+ TC
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTC 2336
Score = 289 bits (739), Expect = 4e-77
Identities = 362/1508 (24%), Positives = 546/1508 (36%), Gaps = 287/1508 (19%)
Query: 1954 ISCMPGTVRRWNYPS--PLCIA-TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIG 2010
IS PG RW S P C L G + SPGFP YPN +CTW I+
Sbjct: 4 ISIAPGP--RWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
Query: 2011 YGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS 2070
+ + F +F+ E + D L + +GP + + +G LPA ++S + SD++
Sbjct: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA 121
Query: 2071 QNRQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQH 2130
+ QGF Y+ C +P NG S +++G V + C G+ L GH VLTC
Sbjct: 122 VSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHA 181
Query: 2131 GINRN--WNYPFPRC--DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVY 2186
G + W++P P C D CG + Q+G I SP FP EY DC W I G +
Sbjct: 182 GSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIA 241
Query: 2187 INFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+ F Q E D++ V G + +S F+G + SS N + L F SD G
Sbjct: 242 LVFIDFQLEDGYDFLEV-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSD---GNH 294
Query: 2247 FVLNFHA-FQLKK----------------------------------CQPPPAVPQAEML 2271
F A +Q+KK P P +P+
Sbjct: 295 RQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKR 354
Query: 2272 TEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQL--QFEGSLPTCEAQCPANEVRTGS 2329
DF +G V++ C+ GY L G+ +TC S + + P C A+ +R G
Sbjct: 355 L-GSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR-GP 412
Query: 2330 SGVILSPGYPGNYFNSQTCSWSI-KVEPNYNITIFVDTFQSEKQFDALEVFDG--SSGQS 2386
SG+I SP +P Y N+ C W I + P+ I + + F E+ +D L V DG Q
Sbjct: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQK 472
Query: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY-AAPYCSLTHP-LKNGGI 2444
+L +L+G S ++Q++L + TD + S GFK Y S P + G
Sbjct: 473 TVLYILTGTSVPDL-IVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR 531
Query: 2445 LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGN 2504
+ G + + C+P + +VG TC++N QW + P C SC + +
Sbjct: 532 REGSRFHHGDTLKFECQPAFELVGQKAITCQKN----NQWSAKKPGC-VFSCFFNFTSPS 586
Query: 2505 GSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQ 2564
G + D C +W +P + +A I+ +
Sbjct: 587 GVVLSPNYPEDYGNHLHC--------------------VWLILARPESRIHLAFNDIDVE 626
Query: 2565 LSEHVIWRLVSGSLNE-------YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPS 2617
+ + G+ E G Q+ S + ++ + G +
Sbjct: 627 -PQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
Query: 2618 CRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYT-LVGSHVRECL---ANGLWSGSE 2673
R C P NG + G G++ F C+ G+ GS C+ + +W+ +
Sbjct: 686 FRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
Query: 2674 TRCLA---GHCGSPDPIVNGHISGDGFS--YRDTV----VYQCNPGFRLVGTSVRICLQD 2724
RC A GH SP +G I G+ Y+D + V + PG+ ++I
Sbjct: 746 LRCEAPCGGHLTSP----SGTILSPGWPGFYKDALSCAWVIEAQPGY-----PIKITFDR 796
Query: 2725 HKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ 2784
K P G +G++ + + T N YLL ++ Q
Sbjct: 797 FKTEVNYDTLEVRDGRTYSAPLIGVYHGTQ--VPQFLISTSNYLYLLFSTDKSHSDIGFQ 854
Query: 2785 WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMA 2844
T + +C DPG N RHG F G + + C G+ L L C
Sbjct: 855 LRYETITLQSDHCLDPGIPVNGQRHG-----NDFYVGALVTFSCDSGYTLSDGEPLECEP 909
Query: 2845 NGLWDRSLPKCLAISCG-----------HPG----VPANAVLTGELFT-YGAVVHYSCRG 2888
N W R+LP C A+ CG PG P N T + T +G V ++
Sbjct: 910 NFQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHT 968
Query: 2889 SESLIGNDTRVCQEDSHWSGALPHCTGNN---------------------------PGF- 2920
G+D + E+ ++ L TG+ GF
Sbjct: 969 FHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFN 1028
Query: 2921 ----------CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL--LNGSWS 2968
C +P PA+ R G F L FSC G++L G+ TCL WS
Sbjct: 1029 ITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
Query: 2969 GLQPVCEAVSCGNPGTPTNGMIVSSD----------------------------GILFSS 3000
P C A CGN T T G ++S + S
Sbjct: 1089 SPLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSE 1147
Query: 3001 SVIYACWEGYKTSGLM------------TRHCTANGTWTGTAPDC--------------T 3034
+ ++G S + T + T++ W D
Sbjct: 1148 GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFE 1207
Query: 3035 IISCGDPGTLANGIQFGTDFTF-NKTVSYQCNPGYVMEAVTSATIRCTKDGR--WNPSKP 3091
+I C DPGT G + + F +VS+ C+PGY + S + C R W+ P
Sbjct: 1208 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRG--SEELLCLSGERRTWDRPLP 1265
Query: 3092 VCKA-------------VLCP-QPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILS 3137
C A VL P P P ++ + W C G H +
Sbjct: 1266 TCVAECGGTVRGEVSGQVLSPGYPAPYEHNL----NCIWTIEAEAGCTIGL---HFLVFD 1318
Query: 3138 CEG----RGVWKGEIPQ-CLPVFCGDPGIPAEGRLSGKSFTYK-SEVFFQCKSPFILVGS 3191
E +W G + L P +P + + S + S FF K F + S
Sbjct: 1319 TEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378
Query: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQ 3251
+C DPG P G S +E G + F+C GY +Q
Sbjct: 1379 VSTA-------------------TSCNDPGIPQNG-SRSGDSWEAGDSTVFQCDPGYALQ 1418
Query: 3252 GSTTRTCL 3259
GS +C+
Sbjct: 1419 GSAEISCV 1426
Score = 112 bits (281), Expect = 5e-24
Identities = 136/585 (23%), Positives = 202/585 (34%), Gaps = 102/585 (17%)
Query: 2599 RLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGS 2658
RL+ W + P +C PNG YG C T
Sbjct: 2 RLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQ 61
Query: 2659 HVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSV 2718
H + + + L+ G P P N GF T+V S+
Sbjct: 62 HRIQLVFQSFALEEDFDVLSVFDGPPQP-ENLRTRLTGFQLPATIVSAATT------LSL 114
Query: 2719 RICLQDHKWSGQT-----PVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG 2773
R+ + D+ S Q V TCG+PG +G GS FNL D V ++CN G+ L+G
Sbjct: 115 RL-ISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEG 173
Query: 2774 VSRAQCRSNGQ----WSSPLPTCRVVNC------------SDPGFVENAIRHGQQNFPES 2817
+ C + + W PLP+CR + S P F + +
Sbjct: 174 HAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTIL 233
Query: 2818 FEYGMSIL-----YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT 2872
E G +I + + G+ L + + LW + + +
Sbjct: 234 AELGDTIALVFIDFQLEDGYDFLEVTGTE--GSSLWFTGASLPAPVISSKNWLRLHFTSD 291
Query: 2873 GELFTYGAVVHYSCRGSESLIGNDTRV--CQEDSHWSGALPHC-TGNNPGFCGDPGTPAH 2929
G G Y + L ++ +++S + L C DPG P
Sbjct: 292 GNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPER 351
Query: 2930 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL----LNGSWSGLQPVCEAVSCGNPGTP 2985
G RLG DF+ S ++F+C G+ L+GS TC+ + +WS +PVC A C
Sbjct: 352 GKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRG 411
Query: 2986 TNGMIVSSD---------------GILFSSSVIYACWE------GYKT-----SGLMTRH 3019
+G+I S + L S VI +E GY T G
Sbjct: 412 PSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQ 471
Query: 3020 CTANGTWTGTA-PDCTII------------------------------SCGDPGTLANGI 3048
T TGT+ PD + SCGDPG A G
Sbjct: 472 KTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGR 531
Query: 3049 QFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVC 3093
+ G+ F T+ ++C P + E V I C K+ +W+ KP C
Sbjct: 532 REGSRFHHGDTLKFECQPAF--ELVGQKAITCQKNNQWSAKKPGC 574
Score = 96.3 bits (238), Expect = 5e-19
Identities = 217/1020 (21%), Positives = 341/1020 (33%), Gaps = 220/1020 (21%)
Query: 2495 SCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCK 2554
+CG P NG G+ F L KV Y C+ GF LE T + + P+C+
Sbjct: 138 TCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
Query: 2555 P--------------VACPSIEAQLSEHV--IWRLVSGSLNEYGAQVLLSCSPGYYLEGW 2598
++ P ++ + W +++ E G + L +G+
Sbjct: 198 ADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILA----ELGDTIALVFIDFQLEDGY 253
Query: 2599 RLLRC---QANGTWNIGDERPSCRVISCG--SLSFPPNGNKIGTLTVYGATAIFTCNTGY 2653
L + + W G P+ + S L F +GN G +A +
Sbjct: 254 DFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNH----RQRGFSAQYQVKKQI 309
Query: 2654 TLVGSHVRECLANGLWSGSETRCLA------GHCGSPDPIV--NGHISGDGFSYRDTVVY 2705
L V+ L + +T L GH PDP + G G F +V +
Sbjct: 310 ELKSRGVK--LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQF 367
Query: 2706 QCNPGFRLVGTSVRICLQDHK----WSGQTPVCVPITC-----GHPG------------N 2744
CN G+ L G+ C++ WS PVC C G G N
Sbjct: 368 TCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDN 427
Query: 2745 PAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVN-CSDPGFV 2803
AH + N + V+ L +G GQ ++ S P +
Sbjct: 428 NAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLI 487
Query: 2804 ENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHP 2863
S + M +L+ LG A S + SCG P
Sbjct: 488 V------------STNHQMWLLFQTDGSGSSLGFKA-----------SYEEIEQGSCGDP 524
Query: 2864 GVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD 2923
G+PA G F +G + + C+ + L+G CQ+++ WS P C + C
Sbjct: 525 GIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFS----CFF 580
Query: 2924 PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPG 2983
T G L ++ C + PE L + ++P + + +
Sbjct: 581 NFTSPSGVVLSPNYPEDYGNHLHCVW--LILARPESRIHLAFNDIDVEPQFDFLVIKDGA 638
Query: 2984 TPTNGMIVSSDGILFSSSVIYACWEGYKTS-GLMTRHCTANGTWTGTAPDCTIISCGDPG 3042
T ++ + G SS+ + G+ T H T + T C DPG
Sbjct: 639 TAEAPVLGTFSGNQLPSSITSS---GHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
Query: 3043 TLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCT-KDGR--WNPSKPVCKAVLCP 3099
NG +FG ++S+ C+ G+ + S TI C K+G WN + C+A C
Sbjct: 696 VPVNGKRFGDSLQLGSSISFLCDEGF-LGTQGSETITCVLKEGSVVWNSAVLRCEAP-CG 753
Query: 3100 QPPPVQNGTVEGSDFRWGSSISYSC------MDGY-----------QLSHSAILSCEGR- 3141
+GT+ + + SC GY ++++ + +GR
Sbjct: 754 GHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRT 813
Query: 3142 ------GVWKG-EIPQCL--------------------------------PVFCGDPGIP 3162
GV+ G ++PQ L C DPGIP
Sbjct: 814 YSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIP 873
Query: 3163 AEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC-------IDPAHN 3215
G+ G F + V F C S + L C+ + WS P+C I +
Sbjct: 874 VNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSG 933
Query: 3216 TCPDPGTPHFGIQNSSRGYEV----GSTVFFRCRKGYHIQ-----------GSTTRTCLA 3260
T PG P F N + + + G VFF +H++ GS T+ L
Sbjct: 934 TILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHT-FHLESGHDYLLITENGSFTQP-LR 991
Query: 3261 NLTWSGIQ--------------------------------TECIPHACRQPETPAHADVR 3288
LT S + +E C +PE PA++ +
Sbjct: 992 QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRK 1051
Query: 3289 AIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMK--WTGKSPVCKSKGVREVNETVTKT 3346
+ G TL ++C PG+ L G+ TC + W+ P C V E +VT T
Sbjct: 1052 GLQFGV-GDTLTFSCFPGYRLE-GTARITCLGGRRRLWSSPLPRC----VAECGNSVTGT 1105
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 4149 bits (10761), Expect = 0.0
Identities = 1908/3254 (58%), Positives = 2415/3254 (74%), Gaps = 45/3254 (1%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
CGG ++G NGTIESPGFP+GYPN ANCTW+II ERNRIQ+ F +FALEE++D LS+YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEI 151
P N + RL+GF LP + ST S+ +L T+DFAVSA GFK YE L S +CGNPG
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVP 184
Query: 152 LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGT 211
KGVL+GTRF++GDKIRYSC+ GYIL+GH LTCI + N ASWDFP P CRAE ACGGT
Sbjct: 185 PKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGT 244
Query: 212 LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPS 271
+RG+S ISSP FP+EY NNADCTWTI+AEPGDTI+L+FTDFQ+EE YD+LEI G+E P+
Sbjct: 245 MRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPT 304
Query: 272 IWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGS 331
IWL+GMN+P P+IS+KNWLRLHF +DSNHR +GF+A +QVKKAI+ KSRG K+ P KD S
Sbjct: 305 IWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
Query: 332 HKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQ 391
+K S+L++GG+ S++CPDPG PENG+R GSDFS +G+ VQFSC+++YVLQG+KSITCQ
Sbjct: 365 NKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFS-LGSTVQFSCDEDYVLQGAKSITCQ 423
Query: 392 RVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVI 451
R+ E AAWSDHRP+C+ +TCGSNL+GPSG TSPN+P QY+ NA CVWVIT + +KVI
Sbjct: 424 RIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVI 483
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
++ FEEF+LE GYDTLT+GD G+VGD R+VL VLTGS VPDLIVSMS+QMWLHLQ+D+S+
Sbjct: 484 QINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESV 543
Query: 512 GSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQN 571
GS GFK Y+EIEK CGDPG P YG R G F + D L FEC FEL+GE+ I CQ+N
Sbjct: 544 GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQEN 603
Query: 572 NQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFD 631
NQWS N P C+F C NFTA G +LSP+YPE YGNN+NC+W IIS+PGSRIHL FNDFD
Sbjct: 604 NQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFD 663
Query: 632 VEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYT 691
+E QFDFLAVKD + +LGTF+G EVPS L S+ HI+RLEFQ+DHS +GRGFNITY
Sbjct: 664 LESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN 723
Query: 692 TFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSST 751
TFG NEC DPGIPIN RRFGD F LGSS+S C++GF+KTQG+E+ITCIL DG V+WS
Sbjct: 724 TFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 783
Query: 752 VPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYD 811
+P+C APCGGH +A SGVIL PGWPGYYKDSL+CEW+IEA+PGHSIKITF+RFQTE+NYD
Sbjct: 784 IPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYD 843
Query: 812 TLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLES 871
LEV DGP SPL+G Y+GTQ PQFL S+ NF+YLLFTTDNSRS+ GF IHYESVT+ +
Sbjct: 844 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 903
Query: 872 DSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALC 931
SCLDPGIPV+G R+G DF I STV+FSCD GY LS +EPL+CE+NH W+H LP+CDALC
Sbjct: 904 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
Query: 932 GGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDG 991
GG ++G SGT+LSPG+P+FYPNSLNCTWT++V+HGKGVQ FHTFHLE HDYLLITE+G
Sbjct: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
Query: 992 SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGV 1051
SF++P+ARLTGS LP TI AGL+GNF AQLRFISDFSISYEGFNITFSEY+LEPC+DPG+
Sbjct: 1024 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1083
Query: 1052 PAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG 1111
P + RIGF+FG+GD+LTFSC GYRLEG +++ CLGGGRRVWSAPLPRCVAECGAS
Sbjct: 1084 PQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATN 1143
Query: 1112 NEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPL 1171
NEG LLSPN+P NY+NNHECIY I+ +AGKGI++ R+F L +GD LK+YDGKD ++ L
Sbjct: 1144 NEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLL 1203
Query: 1172 GTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIR 1231
G FT + GL L+STSN LWLEFN++ TD+GFQL YTSF+L CEDPGIP +GY+I
Sbjct: 1204 GAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKIS 1263
Query: 1232 DEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRIL 1291
D+GHF + ++Y CNPGY +HGS+ L C++G+RR WD PLPSCIAECGG+ +SGRIL
Sbjct: 1264 DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRIL 1323
Query: 1292 SPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSG 1351
SPGYP PYDNNL C W+IE DPG +SL F+ FDTE +HDIL+VWDGP ++D+LLKE SG
Sbjct: 1324 SPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISG 1383
Query: 1352 SALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAG 1411
S +PE IHST N +T+QFD+DF+ISKSGF+IQFS+S+A C DPG+P NGTR GD RE G
Sbjct: 1384 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPG 1443
Query: 1412 DTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQP 1471
DTV FQCDPGY+LQG+ +ITC+Q+ NR+FWQP PP CIA CGGNLTG +G ILSPN+P P
Sbjct: 1444 DTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHP 1503
Query: 1472 YPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERI 1531
YP ++CDW + VN D+VI+L F SF++EP+YDFL+IY+G DSNSPLIGS+Q S+ PERI
Sbjct: 1504 YPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI 1563
Query: 1532 ESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQC 1591
ESS N++ LAFRSD SV +GF +E+K K RE+CFDPGNIMNGTR+G D+KLGST+TY C
Sbjct: 1564 ESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYC 1623
Query: 1592 DSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQI 1651
D+GY + S++TC++G DG+P W++ LPSC+APCG + TGSEG VLSPNYP NY+ G
Sbjct: 1624 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHN 1683
Query: 1652 CLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQ 1711
C+YSI VPKEFVVFGQF +FQT+L+D+ E++DG Q+ LLSSLSGSHSGE+LPL++ NQ
Sbjct: 1684 CVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQ 1743
Query: 1712 ILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPG 1771
I +RF++ +A+GFHFVYQAVPRTS TQCSSVPEPR+GRRIG+EF+ GS V F+CNPG
Sbjct: 1744 ITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPG 1803
Query: 1772 YLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIW 1831
Y+L GS A+ C++VPN+LAQWND++P+C+VPC G T+R+GTILSPGYPEPY NNLNC+W
Sbjct: 1804 YILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVW 1863
Query: 1832 KIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYL 1891
KI V EG+GIQ+QV+SFATE NWDSL+ +DGGD APRLGS+SGTT+P LLNSTSN LYL
Sbjct: 1864 KITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYL 1923
Query: 1892 HFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGR 1951
+FQSDISV+AAGFHLEY +GL +C EP PS+ IKIGDRYMV DV+SFQC+ GY+LQG
Sbjct: 1924 NFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGH 1983
Query: 1952 SHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 2011
SHI+CMPG VRRWNYP P+C+A CGG +S GVILSPGFPG+YP++LDCTW I+LPIG+
Sbjct: 1984 SHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF 2043
Query: 2012 GAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQ 2071
G H+QF+NFSTE HD+LE+++G TS +IG+ SG +P++L STTHET ++F+SD+SQ
Sbjct: 2044 GVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQ 2103
Query: 2072 NRQGFKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHG 2131
N+QGF + YQAY+LQ+CPDP PF+NG++I +D++VGQ++SFEC+PGY LIG+ LTC HG
Sbjct: 2104 NKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHG 2163
Query: 2132 INRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTL 2191
++RNWN+P PRC+A CG N+T+ NGTIYSPG+PDEYP +DC WL+ VPPG+G+YINFT+
Sbjct: 2164 VSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV 2223
Query: 2192 LQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNF 2251
LQTE + D+I VWDGPDQNSPQ+G FSGNTALE+ YS++NQ+L+KFHSDF+ GFFVL++
Sbjct: 2224 LQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSY 2283
Query: 2252 HAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEG 2311
HA+QL+ CQPPP VP AE+LTEDD+FEIGD ++YQC PG+TLVG ILTC+L +LQ +G
Sbjct: 2284 HAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG 2343
Query: 2312 SLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK 2371
+ P C+ CPANE+R S+GVILSPGYP +Y N Q C+WSI VE YNIT+FV+ FQ+EK
Sbjct: 2344 APPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
Query: 2372 QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAP 2431
+FD L+V+DG + QSP+L+ LSG+++ N TS ++++L+WS DH +KKGF+IRY A
Sbjct: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF 2463
Query: 2432 YCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLC 2491
YCS +G I+++T G + S V + C G+R+VG S+A CR++ G + WD+ P C
Sbjct: 2464 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2523
Query: 2492 QAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPP 2551
QA+SCGIP++P NG ++ + ++V Y C++G++L S + TAVCQ DG WSN K P
Sbjct: 2524 QAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTP 2583
Query: 2552 TCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
C ++C + + + I G+ YG+ + +C G+ L G + C ++G W+
Sbjct: 2584 RCVVISCGELPTPPNGNKI-----GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSE 2638
Query: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSG 2671
+ R C CG NG IG Y T ++ CN G+ L+GS VR C + WSG
Sbjct: 2639 SETR--CLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSG 2696
Query: 2672 SETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
C+ CG P + G SG+GF++ D V + CN G+ + G + C + +WS
Sbjct: 2697 QLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPP 2756
Query: 2732 PVCVPITCGHPGNPAHGFTNG----SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSS 2787
P+C + C PG PA+ F VV + CN GY L G S C+ NGQW
Sbjct: 2757 PMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDK 2816
Query: 2788 PLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGL 2847
PLP C +++C PG NA+ G E + +G ++ Y C LLG S+ TC NG
Sbjct: 2817 PLPECIMIDCGHPGVPPNAVLSG-----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
Query: 2848 WDRSLPKC---LAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDS 2904
W S P C +CG PG P + F + V Y+C L G++ R C +
Sbjct: 2872 WSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 2931
Query: 2905 HWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKT-KSLLRFSCEMGHQLRGSPERTCLL 2963
W+G P C CG+PGT A+G D T S + +SC G+ L G R C
Sbjct: 2932 SWTGRQPECKAVQ---CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTA 2988
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGY--KTSGLMTRHCT 3021
NG+WSG P C +SCG+PG P NG+ D ++ +V Y C GY + +G R CT
Sbjct: 2989 NGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVV-GQNVSYMCQPGYTMELNGSRIRTCT 3047
Query: 3022 ANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCT 3081
NGTW+G P C ++C P ++NG GT+F + ++SY C+PGY E A + C
Sbjct: 3048 INGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGY--ELSFPAVLTCV 3105
Query: 3082 KDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGR 3141
+G W+ P C C P G EG F + S +S+SC + L S+ C+
Sbjct: 3106 GNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQAD 3165
Query: 3142 GVWKGEIPQCL---PVFCGDPGIPAEGRLSGK-SFTYKSEVFFQCKSPFILVGSSRRVCQ 3197
G W G P C+ C +PG+P G + F S V F CK +L GS+ R C
Sbjct: 3166 GTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL 3225
Query: 3198 ADGTWSGIQPTCIDPAHNTCPDPGTPH----FGIQNSSRGYEVGSTVFFRCRKGYHIQGS 3253
D TWSGIQP CI ++C P TP G+ S GY T+ + C+ G+ + G
Sbjct: 3226 PDLTWSGIQPECIP---HSCKQPETPAHANVVGMDLPSHGY----TLIYTCQPGFFLAGG 3278
Query: 3254 TT-RTCLANLTWSG 3266
T R C ++ TW+G
Sbjct: 3279 TEHRVCRSDNTWTG 3292
Score = 1503 bits (3892), Expect = 0.0
Identities = 978/2999 (32%), Positives = 1460/2999 (48%), Gaps = 204/2999 (6%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNR-IQLSFHTFALEEDFDIL 86
K + CG +QGP+GT SP FP Y + A C W+I N+ IQ++F F LE +D L
Sbjct: 440 KVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTL 499
Query: 87 SVYDGQPQQGNLKVR--LSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
++ DG V L+G +P IVS S + L TD +V + GFK Y+ + +
Sbjct: 500 TIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKES 559
Query: 145 CGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
CG+PG L G+ G F+ D +R+ C G+ L G + C W P C
Sbjct: 560 CGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPICIF 615
Query: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
C ++ SP +P Y NN +C WTI+++PG I L F DF LE +DFL +
Sbjct: 616 --PCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAV 673
Query: 265 SGTEAPSI----WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
++P TG +PS + S+ + LRL F +D + +GFN +
Sbjct: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN---------- 723
Query: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
+ CPDPGIP N RR G +F ++G+++ CE+ +
Sbjct: 724 ----------------------TFGHNECPDPGIPINARRFGDNF-QLGSSISVICEEGF 760
Query: 381 V-LQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+ QG+++ITC + + WS P C A CG + PSGVI SP +P Y+D+ +C
Sbjct: 761 IKTQGTETITC-ILMDGKVMWSGLIPKCGA-PCGGHFSAPSGVILSPGWPGYYKDSLNCE 818
Query: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
WVI +P IK+ FE F+ E YD L V D + +L G+ VP + S SN
Sbjct: 819 WVI-EAEPGHSIKITFERFQTELNYDVLEVHDGPNL--LSPLLGSYNGTQVPQFLFSSSN 875
Query: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKG--GCGDPGIPAYGKRTGSSFLHGDTLTFECPAA 557
++L +D+S + GFK Y+ + C DPGIP +G+R G F G T++F C +
Sbjct: 876 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 935
Query: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
+ L E + C++N+ WS P+C C + SG ILSP YPE Y N++NC W +
Sbjct: 936 YRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV 995
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---SGHIVRLE 674
G + F+ F +E D+L + ++G S L +G+++P + + +L
Sbjct: 996 THGKGVQFNFHTFHLEDHHDYLLITENG-SFTQPLARLTGSDLPPTINAGLYGNFRAQLR 1054
Query: 675 FQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGS 734
F SD S + GFNIT++ + C DPGIP G R G F +G +++F C G+ + +G+
Sbjct: 1055 FISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGY-RLEGT 1113
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
I C L G VWS+ +PRC A CG T + G++L P +P Y+++ C + I+ + G
Sbjct: 1114 SEIIC-LGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAG 1172
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF-LISTGNFMYLLFTTDN 853
I I+ F D L++ DG ++ L+G + G L ST N ++L F +D
Sbjct: 1173 KGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDT 1231
Query: 854 SRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEP 911
+ GF + Y S E C DPGIP G++ G F ST+ + C+PGYTL
Sbjct: 1232 EGTDEGFQLVYTS--FELSHCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSL 1288
Query: 912 LVCERNHQ--WNHALPSCDALCGGYIQGK-SGTVLSPGFPDFYPNSLNCTWTIEVSHGKG 968
L C + W++ LPSC A CGG +G+ SG +LSPG+P Y N+L C W IEV G
Sbjct: 1289 LKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNI 1348
Query: 969 VQMIFHTFHLESSHDYLLITEDGSFSEPVAR-LTGSVLPHTIKAGLFGNFTAQLRFISDF 1027
V + F F E+SHD L + + ++ + + ++GS++P I + L ++F +DF
Sbjct: 1349 VSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL---NIVTIQFDTDF 1405
Query: 1028 SISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCL 1087
IS GF I FS C DPGVP R G GD++ F C GY L+G ++TC+
Sbjct: 1406 YISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCI 1465
Query: 1088 G-GGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 1146
R W P C+A CG ++ G+ G +LSPNFP Y ++ +C + I A I L
Sbjct: 1466 QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLA 1525
Query: 1147 TRSFQLFEG-DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQG 1205
SF + D L +YDG DS+S +G+F ++L I S+SN + L F ++GS + G
Sbjct: 1526 FISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERI-ESSSNTMHLAFRSDGSVSYTG 1584
Query: 1206 FQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD-- 1263
F L Y + C DPG G R+ + TV Y C+ GY + G +TLTC+ GD
Sbjct: 1585 FHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYY-CDAGYVLQGYSTLTCIMGDDG 1643
Query: 1264 RRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIV 1323
R W++ LPSC A CG + + G +LSP YP Y +C + I + F+
Sbjct: 1644 RPGWNRALPSCHAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVF 1702
Query: 1324 FDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIH-STFNSLTLQFDSDFFISKSGFSI 1382
F T + HD+++V+DGP LL SGS E + S+ N +T++F S I+ GF
Sbjct: 1703 FQTSL-HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHF 1761
Query: 1383 QFST---SIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
+ + + C+ P+ G R G+ G +V F C+PGY L G I C + N
Sbjct: 1762 VYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1821
Query: 1440 F-WQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
W PTCI CGG LT G ILSP YP+PY C W++ V I + SF
Sbjct: 1822 AQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFA 1881
Query: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
E ++D L Y+G D+N+P +GSY G+ P + S+ N+L+L F+SD SV +GF +E+
Sbjct: 1882 TEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1941
Query: 1559 EKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQV 1618
++C +P +G ++G + +G +++QCD GY + S ITC+ G + W+
Sbjct: 1942 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRR--WNYP 1999
Query: 1619 LPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-ALND 1677
+P C A CGG + GV+LSP +P NY + C ++I +P F V QF F T ++D
Sbjct: 2000 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHD 2059
Query: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
E+ G+ + ++ LSG +L +T+++ L F + + +GFH VYQA
Sbjct: 2060 YLEVRSGSSETSTVIGRLSGPQIPSSL-FSTTHETSLYFHSDYSQNKQGFHIVYQAY--- 2115
Query: 1738 SDTQCSSVPEPRYGRR---IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
Q S P+PR R IG++F+ G + FEC PGY L G++AL C + WN
Sbjct: 2116 ---QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTC--LHGVSRNWNH 2170
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
+P C C GN T GTI SPGYP+ Y N +C W + V G+GI I TE +
Sbjct: 2171 PLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY 2230
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D + + DG D +P++G FSG T + STSNQ+ + F SD + + F L Y L
Sbjct: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQLR 2289
Query: 1915 ACQEPALPSNS--IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
CQ P N+ + D + + D++ +QC PG+TL G + ++C G + + P+C
Sbjct: 2290 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
Query: 1973 ATCGGTLSTLG--GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
C L GVILSPG+P SYPN C W IS+ GY + F TE D L+
Sbjct: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2409
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAA--LLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
+ +GP SP++ SG D +A + S HE + + +DH N++GF++ Y A+ +
Sbjct: 2410 VYDGPNIQSPVLISLSG-DYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYC-ST 2467
Query: 2089 PDPPPFQNGYMIN-SDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFPRCD 2144
P+ PP +GY+I+ + + V + C G+ L+G C+ +G + W+ P P C
Sbjct: 2468 PESPP--HGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHA-WDAPVPACQ 2524
Query: 2145 A-PCGYNVTSQNGTIYSPGF----------PDEYPILKDCIWLITVPPGHGVYINFTLLQ 2193
A CG NG I + + D Y + + V G + N
Sbjct: 2525 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKEL-TTAVCQSDGTWSNHNKTP 2583
Query: 2194 TEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHA 2253
V + P+ N G+TA+ T V S+G +
Sbjct: 2584 RCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
Query: 2254 FQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
C P + +++ E+ + D V YQC+PG+ L+G+ + C+ + G L
Sbjct: 2644 L-AGHCGIPELIVNGQVIGENYGYR--DTVVYQCNPGFRLIGSSVRICQ--QDHNWSGQL 2698
Query: 2314 PTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQF 2373
P+C V +S G+PG+ +T + +
Sbjct: 2699 PSC---------------VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTK 2743
Query: 2374 DALEVFDGSSGQSPLLVVLS------------GNHTEQSNFTSRS------NQLYLRWST 2415
+ S P+ V++ + E NFT + N Y + +
Sbjct: 2744 AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGS 2803
Query: 2416 DHATSKKGFKIRYAAPYCSLT---HP-LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSN 2471
+ + P C + HP + +L+ GS VHY C ++G S+
Sbjct: 2804 SVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSS 2863
Query: 2472 ATCRRNPLGMYQWDSLTPLCQ---AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKL 2528
TC+ N W P C +CG P +PG+GS + F S V Y C G+ L
Sbjct: 2864 RTCQLNG----HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYIL 2919
Query: 2529 ESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLS 2588
S++ T C +G W+ G+ P CK V C + + V + G+ + + V+ S
Sbjct: 2920 HGSEERT--CLANGSWT--GRQPECKAVQCGNPGTTANGKVF--RIDGT--TFSSSVIYS 2971
Query: 2589 CSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFT 2648
C GY L G + +C ANGTW+ P+C +ISCG P NG + G V G +
Sbjct: 2972 CMEGYILSGPSVRQCTANGTWS--GTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYM 3029
Query: 2649 CNTGYT--LVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQ 2706
C GYT L GS +R C NG WSG C A C +P I NG + G F + ++ Y
Sbjct: 3030 CQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYI 3089
Query: 2707 CNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCN 2766
C+PG+ L +V C+ + WSG+ P C+P CG PG PA G G F V+F+CN
Sbjct: 3090 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCN 3149
Query: 2767 TGYLLQGVSRAQCRSNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQNFPESFEYGMS 2823
++L G S C+++G WS P C +C +PG RHG QN F+ G
Sbjct: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPG----VPRHGSQNNTFGFQVGSV 3205
Query: 2824 ILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTG-ELFTYGAVV 2882
+ +HCKKG L GS+ TC+ + W P+C+ SC P PA+A + G +L ++G +
Sbjct: 3206 VQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTL 3265
Query: 2883 HYSCRGSESLI-GNDTRVCQEDSHWSGALPHCTGNNPGFCGDP----GTPAHGSRLGDD 2936
Y+C+ L G + RVC+ D+ W+G +P C + DP GTP+ + DD
Sbjct: 3266 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDD 3324
Score = 1382 bits (3576), Expect = 0.0
Identities = 938/2924 (32%), Positives = 1372/2924 (46%), Gaps = 280/2924 (9%)
Query: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
+++C +G I SP +P Y N NC W+II+E +RI ++F F +E ++D+L++
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
D +G +P + S+ + L SD + + GF + Y + C +P
Sbjct: 122 YDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNP 181
Query: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV-WSSTVPRCEA--P 758
G+P G +G RF +G + + C G++ G +TCI N W VP C A
Sbjct: 182 GVPPKGVLYGTRFDVGDKIRYSCVTGYI-LDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
CGG + SSG+I P +P Y ++ C W I A+PG +I + F FQ E YD LE+
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE-- 298
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE------------- 865
S P G P +IS N++ L F TD++ GF Y+
Sbjct: 299 --GSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
Query: 866 -----------------SVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSD 908
+ S+ C DPG P NG R G DF + STV FSCD Y L
Sbjct: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQG 416
Query: 909 DEPLVCERNHQ----WNHALPSCDA-LCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI-E 962
+ + C+R + W+ P C CG +QG SGT SP FP Y ++ C W I
Sbjct: 417 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 476
Query: 963 VSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEP---VARLTGSVLPHTIKAGLFGNFTA 1019
V+ K +Q+ F F LE +D L I + G +P + LTGS +P I + +
Sbjct: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLI---VSMSSQM 533
Query: 1020 QLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLE 1079
L +D S+ GF + + E + E C DPG P + R G F D L F C G+ L
Sbjct: 534 WLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELI 593
Query: 1080 GATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEA 1139
G + C + WSA +P C+ C ++ GT+LSP++P Y NN CI+ I ++
Sbjct: 594 GEKSIVCQENNQ--WSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDP 651
Query: 1140 GKGIHLRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTN 1198
G IHL F L + D L V DG S LGTFT E+ L S S+ L LEF +
Sbjct: 652 GSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPS-HLTSNSHILRLEFQAD 710
Query: 1199 GSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGY-AMHGSNTL 1257
S + +GF +TY +F +C DPGIP R D ++ + C G+ G+ T+
Sbjct: 711 HSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVI-CEEGFIKTQGTETI 769
Query: 1258 TCLSGDRRV-WDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKT 1316
TC+ D +V W +P C A CGG +A SG ILSPG+P Y ++L+C W+IEA+PG +
Sbjct: 770 TCILMDGKVMWSGLIPKCGAPCGGHF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHS 828
Query: 1317 ISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFIS 1376
I + F F TE+ +D+L+V DGP LL ++G+ +P+ + S+ N + L F +D S
Sbjct: 829 IKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
Query: 1377 KSGFSIQFSTSIAAT--CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQ 1434
+GF I + + T C DPG+P +G RYG G TV+F CD GY+L + + C
Sbjct: 889 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC-- 946
Query: 1435 LNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIF 1494
+W PTC A CGG++ GP+G ILSP YP+ YP C W V V + F
Sbjct: 947 -EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
Query: 1495 KSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLF---LAFRSDASVGLS 1551
+F++E +D+L I E PL GS P I + F L F SD S+
Sbjct: 1006 HTFHLEDHHDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
Query: 1552 GFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADG 1611
GF I F E E C DPG G+R+G +F +G T+T+ C SGY++ S I C+ G G
Sbjct: 1065 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG--G 1122
Query: 1612 KPSWDQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYF 1671
+ W LP C A CG T +EG++LSPNYP NY C+YSI V + F
Sbjct: 1123 RRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF 1182
Query: 1672 QTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVY 1731
A D+ +++DG LL + +G+ +TSNQ+ L F++ + + GF VY
Sbjct: 1183 HLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
Query: 1732 QAVPRTSDTQCSSVPEPRYGRRIGSE-FSAGSIVRFECNPGYLLQGSTALHCQSVPNALA 1790
+ + C P++G +I + AGS + + CNPGY L GS+ L C +
Sbjct: 1243 TSFEL---SHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMT--GERR 1297
Query: 1791 QWNDTIPSCVVPCSGNFT-QRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFA 1849
W+ +PSC+ C G F + G ILSPGYP PY NNL C+W I V G+ + +Q ++F
Sbjct: 1298 AWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD 1357
Query: 1850 TEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK 1909
TE + D L + DG L SG+ +P ++ST N + + F +D ++ +GF +++
Sbjct: 1358 TEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFS 1417
Query: 1910 TVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPS- 1968
+ AC++P +P N + GD D + FQC+PGY LQG I+C+ R + PS
Sbjct: 1418 SSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSP 1477
Query: 1969 PLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF 2028
P+CIA CGG L+ G ILSP FP YP++ DC W I++ Y + F++FS E N+DF
Sbjct: 1478 PVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDF 1537
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
L I +GP SP+IG F + LP + S+++ + F SD S + GF L Y+A ++C
Sbjct: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGIN--RNWNYPFPRCDAP 2146
DP NG + DY +G +V++ C GY+L G+ LTC G + WN P C AP
Sbjct: 1598 FDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
CG T GT+ SP +P Y + +C++ I VP V+ F QT +++D + V+DG
Sbjct: 1658 CGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT-SLHDVVEVYDG 1716
Query: 2207 PDQNSPQLGVFSGNTALET-AYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAV 2265
P Q S L SG+ + E+ SS NQ+ ++F S G FH + + P +
Sbjct: 1717 PTQQSSLLSSLSGSHSGESLPLSSGNQITIRF---TSVGPITAKGFHF--VYQAVPRTSS 1771
Query: 2266 PQAEMLTE-------DDDFEIGDFVKYQCHPGYTLVGTDILTCKL--SSQLQFEGSLPTC 2316
Q + E ++F +G V + C+PGY L G+ + C+ +S Q+ SLPTC
Sbjct: 1772 TQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
Query: 2317 EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDAL 2376
C + T G ILSPGYP Y N+ C W I V I + V +F +E +D+L
Sbjct: 1832 IVPC--GGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSL 1889
Query: 2377 EVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA-PYCSL 2435
+ +DG +P L SG T S SN LYL + +D + S GF + Y A S
Sbjct: 1890 DFYDGGDNNAPRLGSYSGT-TIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC 1948
Query: 2436 THP-LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV 2494
P + GI VG V + C GY + GHS+ TC P + +W+ P+C A
Sbjct: 1949 PEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGP--VRRWNYPIPICLA- 2005
Query: 2495 SCGIPESPGNG-----SFTGN-------EFTLDSKVVYECHEGFKLESSQQATAVCQEDG 2542
CG S +G F GN +T++ + + H F S++ D
Sbjct: 2006 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETI-----HDY 2060
Query: 2543 LWSNKGKPPTCKPV---ACPSIEAQL----SEHVIWRLVSGSLNEYGAQVLLSCSPGYYL 2595
L G T + + P I + L E ++ S N+ G ++
Sbjct: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIV--------Y 2112
Query: 2596 EGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTL 2655
+ ++L C D RP NG IG G T F C GYTL
Sbjct: 2113 QAYQLQSCP--------DPRPF------------RNGFVIGNDFTVGQTISFECFPGYTL 2152
Query: 2656 VGSHVRECL--ANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS--------------- 2698
+G+ CL + W+ RC A CG +NG I G+
Sbjct: 2153 IGNSALTCLHGVSRNWNHPLPRCEA-LCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRV 2211
Query: 2699 ------YRDTVVYQCNPGFRLV--------------------------GTSVRICLQDHK 2726
Y + V Q P + + TS +I ++ H
Sbjct: 2212 PPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS 2271
Query: 2727 ---WSG---------QTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
SG Q VC P P A T EF + D++ + C G+ L G
Sbjct: 2272 DFTTSGFFVLSYHAYQLRVCQP---PPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGN 2328
Query: 2775 SRAQCR--SNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGF 2832
+ CR Q P C+V+ ++ +++ +P+S+ L C
Sbjct: 2329 AILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPN----LQMCAWSI 2384
Query: 2833 YLLGSSALTCMANGLWDRSLPKCLAISCGHPGV--PANAVLTGELFTYGAVVHYSCRGSE 2890
+ +T L + G P + P L+G+ Y + + + G E
Sbjct: 2385 SVEKGYNITMFVEFFQTEKEFDVLQVYDG-PNIQSPVLISLSGD---YSSAFNITSNGHE 2440
Query: 2891 SLIGNDTRVCQEDSHWSGALPHCTGNN-PGF--------CGDPGTPAHG---SRLGDDFK 2938
+ WS GNN GF C P +P HG S+ G +
Sbjct: 2441 VFL-----------QWSAD----HGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG--Q 2483
Query: 2939 TKSLLRFSCEMGHQLRGSPERTCLLNG----SWSGLQPVCEAVSCGNPGTPTNGMIVSSD 2994
S++R++C+ G +L G C + +W P C+A+SCG P PTNG I+++D
Sbjct: 2484 LNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTD 2543
Query: 2995 GILFSSSVIYACWEGYKTSG--LMTRHCTANGTWT--GTAPDCTIISCGDPGTLANGIQF 3050
L + V Y C +GY+ S L T C ++GTW+ P C +ISCG+ T NG +
Sbjct: 2544 -YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKI 2602
Query: 3051 GTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE 3110
GT ++ T + C+ G+++ V SA C G W+ S+ C A C P + NG V
Sbjct: 2603 GTQTSYGSTAIFTCDLGFML--VGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI 2660
Query: 3111 GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK 3170
G ++ + ++ Y C G++L S++ C+ W G++P C+PV CG PG P GR SG
Sbjct: 2661 GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN 2720
Query: 3171 SFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNS 3230
F + V F C +++ G ++ CQA+ WS P C C DPG P + S
Sbjct: 2721 GFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMC---KVVNCSDPGIPANSKRES 2777
Query: 3231 S---RGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADV 3287
+ G+ VF+ C GY + GS+ C N W ECI C P P +A V
Sbjct: 2778 KIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA-V 2836
Query: 3288 RAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
+ + TFG T+ Y+C L G S RTC+ + W+G P C
Sbjct: 2837 LSGEKYTFGSTVHYSCTGKRSLLGQSS-RTCQLNGHWSGSQPHC 2879
Score = 1278 bits (3308), Expect = 0.0
Identities = 606/1090 (55%), Positives = 766/1090 (70%), Gaps = 30/1090 (2%)
Query: 2493 AVSCGIPESPGNG---SFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQED--GLWSNK 2547
A C PESP +G S TG + L+S V + C GF+L +++AVC++ G +
Sbjct: 2462 AFYCSTPESPPHGYIISQTGGQ--LNSVVRWACDRGFRLVG--KSSAVCRKSSYGYHAWD 2517
Query: 2548 GKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEY--GAQVLLSCSPGYYLEGWRLLR--C 2603
P C+ ++C +A + ++ +Y G +V C+ GY L L C
Sbjct: 2518 APVPACQAISCGIPKAPTNGGIL-------TTDYLVGTRVTYFCNDGYRLSSKELTTAVC 2570
Query: 2604 QANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVREC 2663
Q++GTW+ ++ P C VISCG L PPNGNKIGT T YG+TAIFTC+ G+ LVGS VREC
Sbjct: 2571 QSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVREC 2630
Query: 2664 LANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQ 2723
L++GLWS SETRCLAGHCG P+ IVNG + G+ + YRDTVVYQCNPGFRL+G+SVRIC Q
Sbjct: 2631 LSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQ 2690
Query: 2724 DHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNG 2783
DH WSGQ P CVP++CGHPG+P +G T+G+ FN NDVV F+CN GYL+QG ++AQC++N
Sbjct: 2691 DHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANR 2750
Query: 2784 QWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCM 2843
QWS P P C+VVNCSDPG N+ R + +F YG + Y C G++L GSS L C
Sbjct: 2751 QWSHPPPMCKVVNCSDPGIPANSKRESKIEHG-NFTYGTVVFYDCNPGYFLFGSSVLICQ 2809
Query: 2844 ANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQED 2903
NG WD+ LP+C+ I CGHPGVP NAVL+GE +T+G+ VHYSC G SL+G +R CQ +
Sbjct: 2810 PNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLN 2869
Query: 2904 SHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLL 2963
HWSG+ PHC+G+ G CGDPGTP HGSR +F+TKS +R++C+ G+ L GS ERTCL
Sbjct: 2870 GHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLA 2929
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN 3023
NGSW+G QP C+AV CGNPGT NG + DG FSSSVIY+C EGY SG R CTAN
Sbjct: 2930 NGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTAN 2989
Query: 3024 GTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKD 3083
GTW+GT P+CTIISCGDPG ANG+++G D+ + VSY C PGY ME S CT +
Sbjct: 2990 GTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTIN 3049
Query: 3084 GRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGV 3143
G W+ P C+AV CP PP + NG +EG++F WG SISY C GY+LS A+L+C G G
Sbjct: 3050 GTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT 3109
Query: 3144 WKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3203
W GE+PQCLP FCGDPGIPA+G+ GKSF Y+SEV F C PFILVGSS R+CQADGTWS
Sbjct: 3110 WSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWS 3169
Query: 3204 GIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLT 3263
G P CI+P +C +PG P G QN++ G++VGS V F C+KG+ +QGSTTRTCL +LT
Sbjct: 3170 GSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLT 3229
Query: 3264 WSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMK 3323
WSGIQ ECIPH+C+QPETPAHA+V +DLP+ GYTL+YTC PGFFLAGG+EHR C++D
Sbjct: 3230 WSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNT 3289
Query: 3324 WTGKSPVCKS------KGVREVNETVT-KTPVPSDVFFVNSLWKGYYEYLGKRQPATLTV 3376
WTGK P+C++ K R T + K VP DVF N +WKG Y + G++QP TLTV
Sbjct: 3290 WTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTV 3349
Query: 3377 DWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQADIFVSKFENDNWGL 3436
FNA++ +VNAT S S +EL L+G+YK +EA L+L+ + IK A V K + +NW +
Sbjct: 3350 TSFNASTGRVNATLSN-SNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAM 3408
Query: 3437 DGYVSSGLERGGFTFQGDIHGKDFGKFKLERQD-PLNPDQDSSSHYHGTSSGSVAAAILV 3495
DG+VS+ + + FQG I GKD+G+F L+R ++ +SS+ HGT+S SVA AILV
Sbjct: 3409 DGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILV 3468
Query: 3496 PFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYDTNLKPTEAKAVRFD 3555
PFFALI +GF FYLYK RT PK QY G + HEN+NGQA+FENPMYDTN K E KAVRFD
Sbjct: 3469 PFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFD 3528
Query: 3556 TTLNTVCTVV 3565
LNTVCT+V
Sbjct: 3529 PNLNTVCTMV 3538
Score = 1210 bits (3131), Expect = 0.0
Identities = 747/2164 (34%), Positives = 1103/2164 (50%), Gaps = 106/2164 (4%)
Query: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVG 470
TCG L+G +G I SP +P Y + A+C WVI + ++ I++ F+ F LE YD L++
Sbjct: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNR-IQIVFQSFALEEEYDYLSLY 122
Query: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
D + LTG +P + S + L L SD ++ + GFK Y+E++ CG+
Sbjct: 123 DGHP--HPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Query: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNN----QWSGNKPSC--VFS 584
PG+P G G+ F GD + + C + L G +TC N+ W P C +
Sbjct: 181 PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Query: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
C SSGII SP++P EY NN +C W I++EPG I LIF DF +E ++D+L + +
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI--E 298
Query: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT------------ 692
G T+ SG +P + S+ + +RL F +D + RGF+ Y
Sbjct: 299 GSEPPTI--WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
Query: 693 --------------------FGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQ 732
N C DPG P NG+R G F LGS+V F CD+ +V Q
Sbjct: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYV-LQ 415
Query: 733 GSESITC-ILQDGNVVWSSTVPRCEA-PCGGHLTASSGVILPPGWPGYYKDSLHCEWIIE 790
G++SITC + + WS P C+ CG +L SG P +P Y + C W+I
Sbjct: 416 GAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT 475
Query: 791 A-KPGHSIKITFDRFQTEVNYDTLEVRDGPASSSP--LIGEYHGTQAPQFLISTGNFMYL 847
A I+I F+ F E+ YDTL + DG P ++ G+ P ++S + M+L
Sbjct: 476 AVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWL 535
Query: 848 LFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLS 907
TD S S+GF ++Y+ + E +SC DPG P+ G R G F R + F C G+ L
Sbjct: 536 HLQTDESVGSVGFKVNYKEI--EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELI 593
Query: 908 DDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGK 967
++ +VC+ N+QW+ +P C C GTVLSP +P+ Y N+LNC WTI G
Sbjct: 594 GEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGS 653
Query: 968 GVQMIFHTFHLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISD 1026
+ + F+ F LES D+L + + S P+ TG+ +P + + + +L F +D
Sbjct: 654 RIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTS---NSHILRLEFQAD 710
Query: 1027 FSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGY-RLEGATKLT 1085
S+S GFNIT++ + C DPG+P +RR G +F +G S++ C G+ + +G +T
Sbjct: 711 HSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETIT 770
Query: 1086 C-LGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
C L G+ +WS +P+C A CG G +LSP +P Y ++ C + IE E G I
Sbjct: 771 CILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK 830
Query: 1145 LRTRSFQL-FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTD 1203
+ FQ D L+V+DG + S LG++ + + L S+SN ++L F T+ S ++
Sbjct: 831 ITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQ-VPQFLFSSSNFIYLLFTTDNSRSN 889
Query: 1204 QGFQLTYTS--FDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLS 1261
GF++ Y S + C DPGIP +G R + T V +SC+ GY + L C
Sbjct: 890 NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGST-VSFSCDSGYRLSHEEPLLC-- 946
Query: 1262 GDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHF 1321
W PLP+C A CGG + SG ILSPGYP Y N+L+CTW ++ GK + +F
Sbjct: 947 EKNHWWSHPLPTCDALCGGDVR-GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
Query: 1322 IVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNS---LTLQFDSDFFISKS 1378
F E HD L + + + L + +GS LP I++ L+F SDF IS
Sbjct: 1006 HTFHLEDHHDYLLITENGSFTQPLAR-LTGSDLPPTINAGLYGNFRAQLRFISDFSISYE 1064
Query: 1379 GFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNR 1438
GF+I FS C DPG+PQ G+R G + GDT+TF C GY+L+G ++I C+ R
Sbjct: 1065 GFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLG-GGR 1123
Query: 1439 FFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
W P C+A CG + T G++LSPNYP Y EC + ++V I + ++F+
Sbjct: 1124 RVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1183
Query: 1499 MEPSYDFLHIYEGEDSNSPLIGSYQG-SQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
+ D L IY+G+D + L+G++ G S + S+ N L+L F SD GF + +
Sbjct: 1184 LAQG-DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
Query: 1558 KEKPREACFDPGNIMNGTRVGTDFKL-GSTITYQCDSGYKILDPSSITCVIGADGKPSWD 1616
C DPG G ++ GSTI Y C+ GY + S + C+ G + +WD
Sbjct: 1243 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGE--RRAWD 1300
Query: 1617 QVLPSCNAPCGGQYTG-SEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQT-A 1674
LPSC A CGG++ G S G +LSP YP Y C++ I V +V QF F T A
Sbjct: 1301 YPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEA 1360
Query: 1675 LNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
+D+ ++DG LL +SGS E + +T N + ++F S GF + +
Sbjct: 1361 SHDILRVWDGPPENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS- 1418
Query: 1735 PRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
+ T C P G R G G V F+C+PGY LQG + C V N W
Sbjct: 1419 --SVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYF-WQP 1475
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
+ P C+ PC GN T G ILSP +P PY ++ +C W I V I + ISF+ E N+
Sbjct: 1476 SPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNY 1535
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D L I+DG D +P +GSF + +P + S+SN ++L F+SD SV+ GFHLEYK
Sbjct: 1536 DFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRE 1595
Query: 1915 ACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRR--WNYPSPLCI 1972
+C +P N ++G Y + +++ C+ GY LQG S ++C+ G R WN P C
Sbjct: 1596 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH 1655
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
A CG + G +LSP +P +Y +C + I++P + QF+ F T HD +E+
Sbjct: 1656 APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL-HDVVEVY 1714
Query: 2033 NGPYHTSPMIGQFSGTDLPAAL-LSTTHETLIHFYSDHSQNRQGFKLAYQAY---ELQNC 2088
+GP S ++ SG+ +L LS+ ++ I F S +GF YQA C
Sbjct: 1715 DGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQC 1774
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGIN--RNWNYPFPRCDAP 2146
P + G I ++++VG SV F+C PGYIL G + C+ N WN P C P
Sbjct: 1775 SSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1834
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDG 2206
CG +T + GTI SPG+P+ Y +C+W ITVP G G+ + TE D + +DG
Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
D N+P+LG +SG T S++N + L F SD S + F L + A L C P P
Sbjct: 1895 GDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSC-PEPQT 1953
Query: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
P + + D + +GD V +QC GY+L G +TC ++ +P C AQC
Sbjct: 1954 PSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC--GGA 2010
Query: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQ 2385
+ SGVILSPG+PGNY +S C+W+I + + + + F +E D LEV GSS
Sbjct: 2011 MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSET 2070
Query: 2386 SPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCSLTHPLKNG 2442
S ++ LSG S F S +++ L + +D++ +K+GF I Y A C P +NG
Sbjct: 2071 STVIGRLSGPQIPSSLF-STTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNG 2129
Query: 2443 GILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESP 2502
++ VG + + C PGY ++G+S TC W+ P C+A+ CG +
Sbjct: 2130 FVIGNDF-TVGQTISFECFPGYTLIGNSALTCLHGV--SRNWNHPLPRCEAL-CGGNITA 2185
Query: 2503 GNGS 2506
NG+
Sbjct: 2186 MNGT 2189
Score = 99.4 bits (246), Expect = 6e-20
Identities = 174/817 (21%), Positives = 291/817 (35%), Gaps = 187/817 (22%)
Query: 2631 NGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCLAGHCGSPDP 2686
NG ++G G+T + C+ GY L G C+ W+ + C A CGS
Sbjct: 1605 NGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRST 1663
Query: 2687 IVNGHISGDGFSYRDTVVYQCNPG------------FRLVGTSVRICLQDHKWSGQTPVC 2734
G + + +V + C F TS+ ++ + Q
Sbjct: 1664 GSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSL 1723
Query: 2735 VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG---VSRAQCRSNGQWSSPLPT 2791
+ G + ++G++ + FT +G V +A R++ S +P
Sbjct: 1724 LSSLSGSHSGESLPLSSGNQIT----IRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVP- 1778
Query: 2792 CRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTC--MANGL-- 2847
+P F + F G S+L+ C G+ L GS A+ C + N L
Sbjct: 1779 -------EPRF--------GRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
Query: 2848 WDRSLPKCLA-------------ISCGHPG-------------VPANAVLTGELFTYGAV 2881
W+ SLP C+ +S G+P VP A + ++ ++
Sbjct: 1824 WNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFAT- 1882
Query: 2882 VHYSCRGSESLIGNDTRVCQEDSHWSGALPHC---TGNN-------------PGF----- 2920
++ + G D + S+ +PH T NN GF
Sbjct: 1883 -EHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1941
Query: 2921 ------CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNG--SWSGLQP 2972
C +P TP+ G ++GD + ++ F C+ G+ L+G TC+ W+ P
Sbjct: 1942 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIP 2001
Query: 2973 VCEAVSCG-----------NPGTPTN---------------GMIVSSDGILFSSSVIYAC 3006
+C A CG +PG P N G V + FS+ I+
Sbjct: 2002 ICLA-QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDY 2060
Query: 3007 WEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNP 3066
E S + T G +G ++ S T + F +D++ NK +
Sbjct: 2061 LEVRSGS---SETSTVIGRLSGPQIPSSLFST----THETSLYFHSDYSQNKQGFHIVYQ 2113
Query: 3067 GYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMD 3126
Y +++ CP P P +NG V G+DF G +IS+ C
Sbjct: 2114 AYQLQS-------------------------CPDPRPFRNGFVIGNDFTVGQTISFECFP 2148
Query: 3127 GYQLSHSAILSCEGRGV---WKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCK 3183
GY L ++ L+C GV W +P+C CG G + + + F C
Sbjct: 2149 GYTLIGNSALTCL-HGVSRNWNHPLPRC-EALCGGNITAMNGTIYSPGYPDEYPNFQDC- 2205
Query: 3184 SPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC-----PDPGTPHFGIQNSSRGYEVGS 3238
F LV RV +G + +P ++ PD +P G + + E
Sbjct: 2206 --FWLV----RVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVY 2259
Query: 3239 TVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLP-TFGY 3297
+ + +H +T+ + L++ Q C+ P +A++ D G
Sbjct: 2260 STSNQILIKFHSDFTTSGFFV--LSYHAYQLR----VCQPPPPVPNAEILTEDDEFEIGD 2313
Query: 3298 TLVYTCHPGFFLAGGSEHRTCKAD--MKWTGKSPVCK 3332
+ Y C PGF L G + TC+ ++ G PVC+
Sbjct: 2314 IIRYQCLPGFTLVGNA-ILTCRLGERLQMDGAPPVCQ 2349
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 516 bits (1329), Expect = e-145
Identities = 399/1403 (28%), Positives = 573/1403 (40%), Gaps = 181/1403 (12%)
Query: 2087 NCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFP----- 2141
+C P +NG + ++ G V++ C GY L G +C N +W++ P
Sbjct: 1846 SCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCL--ANSSWSHSPPVCEPV 1903
Query: 2142 RCDAPCGYN--------VTSQNGTIYS--PGFPDEYPILKDC----IWLITVPPGHGVYI 2187
+C +P N +T + YS G+ + P + +C IW P H V+
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1963
Query: 2188 NFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFF 2247
+ A+ D AV G + ++ A T + L S+
Sbjct: 1964 G----EPPAIKD--AVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCL 2017
Query: 2248 VLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQ- 2306
++ C PP V A T F GD Y C GY+L L C +
Sbjct: 2018 AVS--------CDEPPIVDHASPETAHRLF--GDIAFYYCSDGYSLADNSQLLCNAQGKW 2067
Query: 2307 LQFEGS-LPTCEAQ-CPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV 2364
+ EG +P C A C E S IL + S+ N + +
Sbjct: 2068 VPPEGQDMPRCIAHFC---EKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKI 2124
Query: 2365 DTFQSEKQFDA---LEVFDGSSGQSPLLVVLSGNHTEQSNFT-------SRSNQLYLRW- 2413
+ + + + ++ G+ P ++ + SN++ S + Y++
Sbjct: 2125 ECMRGGQWNPSPMSIQCIPVRCGEPPSIM---NGYASGSNYSFGAMVAYSCNKGFYIKGE 2181
Query: 2414 --STDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAV-GSKVHYFCKPGYRMVGHS 2470
ST AT + I P P G L T G + S+V Y C PGY+ VG
Sbjct: 2182 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSP 2241
Query: 2471 NATCRRNPLGMYQWDSLTPL-CQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLE 2529
C+ N W S +PL C + CG P NG G F + SKV + C+EG++L
Sbjct: 2242 VFVCQANR----HWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELV 2297
Query: 2530 SSQQATAVCQEDGLWSNKGKPPTCKPVACPS---IEAQL-----------------SEHV 2569
T CQ+ G W NK P C P CP +E QL HV
Sbjct: 2298 GDSSWT--CQKSGKW-NKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHV 2354
Query: 2570 I-------------WR---------------LVS------GSLNEYGAQVLLSCSPGYYL 2595
+ W L+S S +G+ V SC G++L
Sbjct: 2355 LQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFL 2414
Query: 2596 EGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTL 2655
G CQ +GTW+ P C + C PNG Y +TA++TC G+ L
Sbjct: 2415 RGNSTTLCQPDGTWS--SPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFEL 2472
Query: 2656 VGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVG 2715
VG+ C NG W G + C A C P I+NG S Y TV Y CN GFRL G
Sbjct: 2473 VGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEG 2532
Query: 2716 TSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVS 2775
S CL+ W P C I C P +GF G++++ ++ ++C G+ + G +
Sbjct: 2533 PSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHA 2592
Query: 2776 RAQCRSNGQWSSPLPTCRVVNCS---------------DPGFVEN--------------- 2805
C +G WSS +PTC ++C D G+ E
Sbjct: 2593 MQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPP 2651
Query: 2806 ----AIRHGQQNFPES-------FEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPK 2854
A+ +N ES F YG + Y C G+ LLG+ L C +G W+ S P
Sbjct: 2652 YHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPS 2711
Query: 2855 CLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCT 2914
C++I C P P N L + G+ V YSC+ L G+D R+C E+ WSGA P C
Sbjct: 2712 CISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Query: 2915 GNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC 2974
+ C P +GS G ++ S L + C+ G+ L G+ RTC + +W +P+C
Sbjct: 2772 AIS---CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Query: 2975 EAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCT 3034
V C +P NG V D F + Y C EG+ G +R C ANG+W+G PDC
Sbjct: 2829 IPVDCSSPPVSANGQ-VRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCV 2887
Query: 3035 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK 3094
+ C P LANG+ G D+ F K V++ C+ GY++ T C DG W+ P+CK
Sbjct: 2888 PVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLT--CQSDGNWDAEIPLCK 2945
Query: 3095 AVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV 3154
V C P + +G G F G I Y C GY+L ++ C G W G P CLP
Sbjct: 2946 PVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPC 3005
Query: 3155 FCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAH 3214
C P I G ++G F QC F L+G S C+ADG WS P C H
Sbjct: 3006 RCSTPVI-EYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC---EH 3061
Query: 3215 NTCPD-PGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIP 3273
+C P P+ I +S E + + + CR GY IQGS+ C WS C P
Sbjct: 3062 TSCGSLPMIPNAFISETSSWKE--NVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEP 3119
Query: 3274 HACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKS 3333
+C P + A+A V + T+ + C G+ + ++ TC+ D +W + C
Sbjct: 3120 LSCGSPPSVANA-VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSP 3178
Query: 3334 KGVREVNETVTKTPVPSDVFFVN 3356
K + E +T V D F VN
Sbjct: 3179 KKC-PLPENITHILVHGDDFSVN 3200
Score = 505 bits (1300), Expect = e-142
Identities = 345/1145 (30%), Positives = 490/1145 (42%), Gaps = 124/1145 (10%)
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
KC PP + + +++ ++ E+G V + C G+ L G +L C L SQ Q+ S P C+
Sbjct: 2322 KCPEPPLL-ENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKC-LPSQ-QWNDSFPVCK 2377
Query: 2318 -------------AQCPANEVRTGSSGVILSPGYPGNYF---NSQTC-----SWSIKVEP 2356
P++ + GS+ + G +F NS T +WS +
Sbjct: 2378 IVLCTPPPLISFGVPIPSSALHFGST---VKYSCVGGFFLRGNSTTLCQPDGTWSSPLPE 2434
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
+ V+ Q E E+ +G L + + +T + F N L
Sbjct: 2435 ----CVPVECPQPE------EIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENG 2484
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNR----TAGAVGSKVHYFCKPGYRMVGHSNA 2472
H K P C LK ILN T G V Y C G+R+ G S
Sbjct: 2485 HWLGGK--------PTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSAL 2536
Query: 2473 TCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ 2532
TC L WD P C A+ C P+ NG G +++ + ++Y C GF++
Sbjct: 2537 TC----LETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHA 2592
Query: 2533 QATAVCQEDGLWSNKGKPPTCKPVAC---PSIE-----------------------AQLS 2566
T C+E G WS+ PTC P+ C P I+ ++
Sbjct: 2593 MQT--CEESG-WSSS--IPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVT 2647
Query: 2567 EHVIWRL---------------VSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
H + L S YG V +C+PGY L G +L CQ +GTWN
Sbjct: 2648 PHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWN- 2706
Query: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSG 2671
PSC I C + P NG T T G+ ++C G+ L GS +R CL N WSG
Sbjct: 2707 -GSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSG 2765
Query: 2672 SETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
+ RC A C P+P++NG I G ++Y T+ Y+C+PG+ L GT R C D W
Sbjct: 2766 ASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDE 2825
Query: 2732 PVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT 2791
P+C+P+ C P A+G G E+ + +TCN G+LL+G C +NG WS P
Sbjct: 2826 PICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPD 2885
Query: 2792 CRVVNCSDPGFVENAIRHGQQNFPESFEYGM--SILYHCKKGFYLLGSSALTCMANGLWD 2849
C V C+ P + N + G +YG + +HC +G+ L G+ LTC ++G WD
Sbjct: 2886 CVPVRCATPPQLANGVTEG-------LDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWD 2938
Query: 2850 RSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGA 2909
+P C ++CG P A+ G F +G + Y C L GN +R C + WSG+
Sbjct: 2939 AEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGS 2998
Query: 2910 LPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSG 2969
P C P C P +G+ G DF R C G +L G E TC +G WS
Sbjct: 2999 SPSCL---PCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSS 3054
Query: 2970 LQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGT 3029
P CE SCG+ N I S + + Y+C GY G CT G W+
Sbjct: 3055 GFPHCEHTSCGSLPMIPNAFI-SETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQP 3113
Query: 3030 APDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPS 3089
P C +SCG P ++AN + G T+ V +C GY M+ T T C KDGRW P
Sbjct: 3114 YPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTD-TFTCQKDGRWFPE 3172
Query: 3090 KPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEI- 3148
+ C CP P + + V G DF +S SC +GY I C+ G W+
Sbjct: 3173 RISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFS 3232
Query: 3149 -PQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQP 3207
C PV CG P P G + G +T++S + +QC+ + L G+ RVCQ + WSG
Sbjct: 3233 DESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVA 3292
Query: 3208 TCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGI 3267
C + T + I+N + G V + C +GY ++G + C N TWS
Sbjct: 3293 ICKETRCETPLEFLNGKADIENRT----TGPNVVYSCNRGYSLEGPSEAHCTENGTWSHP 3348
Query: 3268 QTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGK 3327
C P+ C P + + + C GF L G TC D WT
Sbjct: 3349 VPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHG-IITCNPDETWTQT 3407
Query: 3328 SPVCK 3332
S C+
Sbjct: 3408 SAKCE 3412
Score = 459 bits (1182), Expect = e-128
Identities = 323/1140 (28%), Positives = 471/1140 (41%), Gaps = 137/1140 (12%)
Query: 2283 VKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQC-----------PANEVRTGSS- 2330
V+YQC+PGY VG+ + C+ + E L C GS
Sbjct: 2227 VRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKV 2286
Query: 2331 GVILSPGYPGNYFNSQTCS----WSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQS 2386
+ GY +S TC W+ K P + +
Sbjct: 2287 QFFCNEGYELVGDSSWTCQKSGKWNKKSNP--------------------KCMPAKCPEP 2326
Query: 2387 PLL---VVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLT----HPL 2439
PLL +VL TE T + ++ + + P C + PL
Sbjct: 2327 PLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPL 2386
Query: 2440 KNGGI-LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGI 2498
+ G+ + +A GS V Y C G+ + G+S C+ P G W S P C V C
Sbjct: 2387 ISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQ--PDGT--WSSPLPECVPVECPQ 2442
Query: 2499 PESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC 2558
PE NG S +Y C GF+L + T +C E+G W G PTCK + C
Sbjct: 2443 PEEIPNGIIDVQGLAYLSTALYTCKPGFELVGN--TTTLCGENGHWL--GGKPTCKAIEC 2498
Query: 2559 PSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC 2618
+ L+ + + YG V SC+ G+ LEG L C G W++ + PSC
Sbjct: 2499 LKPKEILNGKFSYTDL-----HYGQTVTYSCNRGFRLEGPSALTCLETGDWDV--DAPSC 2551
Query: 2619 RVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLA 2678
I C S NG G YGA I++C G+ + G ++ C +G WS S C+
Sbjct: 2552 NAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMP 2610
Query: 2679 GHCGSPD--------------------------PIVNGH--------------------I 2692
CG P P V H
Sbjct: 2611 IDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPAT 2670
Query: 2693 SGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNG 2752
F Y V Y CNPG+ L+G V IC +D W+G P C+ I C P P +GF
Sbjct: 2671 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRF 2730
Query: 2753 SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ 2812
+E ++ V ++C G++L G C N +WS P C ++C P V N G
Sbjct: 2731 TETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKG-- 2788
Query: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT 2872
++ Y ++ Y C G+ L G+ TC + WD P C+ + C P V AN +
Sbjct: 2789 ---SNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR 2845
Query: 2873 GELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSR 2932
G+ +T+ + Y+C L G +RVC + WSGA P C P C P A+G
Sbjct: 2846 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCV---PVRCATPPQLANGVT 2902
Query: 2933 LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVS 2992
G D+ + F C G+ L G+P+ TC +G+W P+C+ V+CG P +G +
Sbjct: 2903 EGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG-FPN 2961
Query: 2993 SDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGT 3052
+ + Y C+ GYK G +R C +NG+W+G++P C C P + G GT
Sbjct: 2962 GFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNGT 3020
Query: 3053 DFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGS 3112
DF K QC G+ + ++ T C DG+W+ P C+ C P + N + +
Sbjct: 3021 DFDCGKAARIQCFKGFKLLGLSEIT--CEADGQWSSGFPHCEHTSCGSLPMIPNAFISET 3078
Query: 3113 DFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSF 3172
+ I+YSC GY + S+ L C +GVW P C P+ CG P A +G++
Sbjct: 3079 SSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAH 3138
Query: 3173 TYKSEVFFQCKSPFIL-VGSSRRVCQADGTWSGIQPTCIDPAHNTCPDP-GTPHFGIQNS 3230
TY+SEV +C + + + CQ DG W P I + CP P H +
Sbjct: 3139 TYESEVKLRCLEGYTMDTDTDTFTCQKDGRWF---PERISCSPKKCPLPENITHILVHGD 3195
Query: 3231 SRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSG--IQTECIPHACRQPETPAHADVR 3288
+ V V C +GY +G C + TW C P +C +PE+P H V
Sbjct: 3196 D--FSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVV 3253
Query: 3289 AIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPV 3348
TF T++Y C PG+ L G E R C+ + +W+G +CK ET +TP+
Sbjct: 3254 GSKY-TFESTIIYQCEPGYELEGNRE-RVCQENRQWSGGVAICK--------ETRCETPL 3303
Score = 459 bits (1181), Expect = e-128
Identities = 316/1175 (26%), Positives = 500/1175 (42%), Gaps = 133/1175 (11%)
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
C PP P DDF G V YQC+ GY L+G + C + + G P+C
Sbjct: 1690 CGVPP--PLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFC--TDNGSWNGVSPSC-- 1743
Query: 2319 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEV 2378
+E GS + +C + V+ +Y I V +
Sbjct: 1744 -LDVDECAVGS-----------DCSEHASC---LNVDGSY-ICSCVPPYTG--------- 1778
Query: 2379 FDGSSGQSPLLVVLSGN----------HTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2428
DG + P+ GN +T + T + Y T + + +
Sbjct: 1779 -DGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNH 1837
Query: 2429 AAPYCSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQW 2484
PYC + G + A GSKV Y C GY + G ++C N W
Sbjct: 1838 LIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANS----SW 1893
Query: 2485 DSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 2544
P+C+ V C PE+ NG + + T S Y C G+ L+ + C G+W
Sbjct: 1894 SHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGP--SIIECTASGIW 1951
Query: 2545 SNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2604
PP C V C A + +++G+ + V +C GY L G + C
Sbjct: 1952 DRA--PPACHLVFCGEPPA-----IKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECL 2004
Query: 2605 ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECL 2664
A+G W+ D++ C +SC + + ++G A + C+ GY+L + C
Sbjct: 2005 ADGKWSRSDQQ--CLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCN 2062
Query: 2665 ANGLWSGSE----TRCLAGHCGSPDPI---VNGHISGDGFSYRDTVVYQCNPGFRLVGTS 2717
A G W E RC+A C P + + +S F+ V ++C GF ++ TS
Sbjct: 2063 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGF-VLNTS 2121
Query: 2718 VRI-CLQDHKW--SGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
+I C++ +W S + C+P+ CG P + +G+ +GS ++ +V ++CN G+ ++G
Sbjct: 2122 AKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGE 2181
Query: 2775 SRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA-IRHGQQNFPESFEYGMSILYHCKKGFY 2833
++ C + GQWSSP+PTC V+C +P VEN + H ES + Y C G+
Sbjct: 2182 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFES-----EVRYQCNPGYK 2236
Query: 2834 LLGSSALTCMANGLWDRSLP-KCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESL 2892
+GS C AN W P C+ + CG P N + GE F G+ V + C L
Sbjct: 2237 SVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYEL 2296
Query: 2893 IGNDTRVCQEDSHWSG-ALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGH 2951
+G+ + CQ+ W+ + P C P C +P + L + ++ FSC+ GH
Sbjct: 2297 VGDSSWTCQKSGKWNKKSNPKCM---PAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGH 2353
Query: 2952 QLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYK 3011
L+G CL + W+ PVC+ V C P + G+ + S + F S+V Y+C G+
Sbjct: 2354 VLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFF 2413
Query: 3012 TSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVME 3071
G T C +GTW+ P+C + C P + NGI + T Y C PG+ E
Sbjct: 2414 LRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGF--E 2471
Query: 3072 AVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLS 3131
V + T C ++G W KP CKA+ C +P + NG +D +G +++YSC G++L
Sbjct: 2472 LVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLE 2531
Query: 3132 HSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGS 3191
+ L+C G W + P C + C P G + G ++Y + + + C F + G
Sbjct: 2532 GPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGH 2591
Query: 3192 SRRVCQADGTWSGIQPTCID-----PAHNTCPD------------------------PGT 3222
+ + C+ G WS PTC+ P H D P
Sbjct: 2592 AMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHP 2650
Query: 3223 P-HFGI------------QNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQT 3269
P H G S + G+ V + C GY + G+ C + TW+G
Sbjct: 2651 PYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAP 2710
Query: 3270 ECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSP 3329
CI C P P + +R + + G + Y+C PG LAG S+ R C + KW+G SP
Sbjct: 2711 SCISIECDLPTAPENGFLRFTET-SMGSAVQYSCKPGHILAG-SDLRLCLENRKWSGASP 2768
Query: 3330 VCKSKGVREVNETVTKTPVPSDVFFVNSLWKGYYE 3364
C++ ++ N + + S+ ++++L YYE
Sbjct: 2769 RCEAISCKKPNPVMNGSIKGSNYTYLSTL---YYE 2800
Score = 454 bits (1169), Expect = e-127
Identities = 466/1935 (24%), Positives = 710/1935 (36%), Gaps = 247/1935 (12%)
Query: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI- 1449
+C P +NG D AG TVT+QC+ GY L G +++ C + W P+C+
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGS---WNGVSPSCLD 1745
Query: 1450 ---AACGGNLTGPA------GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNME 1500
A G + + A G + P GK C +K N E
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPG---------NPE 1796
Query: 1501 PSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
+ IY +G+ E + G + S L +
Sbjct: 1797 NGHSSGEIYT--------VGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC------ 1842
Query: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
+C P NG F GS +TY+C+ GY + +C+ + SW P
Sbjct: 1843 KAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANS----SWSHSPP 1898
Query: 1621 SCN-APCGGQYTGSEGVVLSPNYPHNYTAGQICL--YSITVPK--EFVVFGQFAYFQTAL 1675
C C + G + + TA C YS+ P E G
Sbjct: 1899 VCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASG--------- 1949
Query: 1676 NDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLR----FSAKSGASARGFHFVY 1731
++D L+ G + T N R ++ K G + G +
Sbjct: 1950 -----IWDRAPPACHLV--FCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIE 2002
Query: 1732 QAVP---RTSDTQCSSVP--EPRYGRRIGSEFSA---GSIVRFECNPGYLLQGSTALHCQ 1783
SD QC +V EP E + G I + C+ GY L ++ L C
Sbjct: 2003 CLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLC- 2061
Query: 1784 SVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQI 1843
NA +W + C +F ++ P + L + K GS +
Sbjct: 2062 ---NAQGKWVPPEGQDMPRCIAHFCEKP--------PSVSYSILESVSKAKFAAGSVVSF 2110
Query: 1844 QVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTV-----PALLNSTSNQLYLHFQSDIS 1898
+ + +E GG P S V P+++N ++ F + ++
Sbjct: 2111 KCMEGFVLNTSAKIECMRGGQWN-PSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVA 2169
Query: 1899 VAA-AGFHLEYK----------------TVGLAACQEPALPSNS-IKIGDRYMVNDVLSF 1940
+ GF+++ + T +C EP N ++ + + +
Sbjct: 2170 YSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRY 2229
Query: 1941 QCEPGYTLQGRSHISCMPGTVRRWNYPSPL-CIAT-CGGTLSTLGGVILSPGFPGSYPNN 1998
QC PGY G C R W+ SPL C+ CG G + F
Sbjct: 2230 QCNPGYKSVGSPVFVCQAN--RHWHSESPLMCVPLDCGKPPPIQNGFMKGENFE------ 2281
Query: 1999 LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLS-- 2056
G+ +QF F E E+ T G+++ P + +
Sbjct: 2282 ------------VGSKVQF--FCNEG----YELVGDSSWTCQKSGKWNKKSNPKCMPAKC 2323
Query: 2057 ---------------TTHETLIHFYSDHSQNRQGFKL-----------AYQAYELQNCPD 2090
TT ++ F QG + ++ ++ C
Sbjct: 2324 PEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTP 2383
Query: 2091 PPPFQNGYMI-NSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC-DAPCG 2148
PP G I +S G +V + C G+ L G+ CQ + W+ P P C C
Sbjct: 2384 PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQP--DGTWSSPLPECVPVECP 2441
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPD 2208
NG I G L C PG + N T L E + W G
Sbjct: 2442 QPEEIPNGIIDVQGLAYLSTALYTC------KPGFELVGNTTTLCGENGH-----WLGGK 2490
Query: 2209 QNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKK---------- 2258
+ L +S T+ + + N GF + A +
Sbjct: 2491 PTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPS 2550
Query: 2259 -----CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
C P + E D+ G + Y C PG+ + G + TC+ S + S+
Sbjct: 2551 CNAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG---WSSSI 2605
Query: 2314 PTC---EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
PTC + P + + + GY + + + P Y++ T+++
Sbjct: 2606 PTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPY-VTPHPPYHLGAVAKTWENT 2664
Query: 2371 KQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
K+ A S L ++T + N + + + G +
Sbjct: 2665 KESPATH-------SSNFLYGTMVSYTCNPGYELLGNPVLI---CQEDGTWNGSAPSCIS 2714
Query: 2431 PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPL 2490
C L +NG L T ++GS V Y CKPG+ + G C N +W +P
Sbjct: 2715 IECDLPTAPENG-FLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENR----KWSGASPR 2769
Query: 2491 CQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKP 2550
C+A+SC P NGS G+ +T S + YEC G+ L +++ T CQ+D W
Sbjct: 2770 CEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRT--CQDDKNWDED--E 2825
Query: 2551 PTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWN 2610
P C PV C S + V G + ++ +C+ G+ LEG R C ANG+W+
Sbjct: 2826 PICIPVDCSSPPVSANGQV-----RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWS 2880
Query: 2611 IGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWS 2670
P C + C + NG G + F C+ GY L G+ C ++G W
Sbjct: 2881 --GATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWD 2938
Query: 2671 GSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQ 2730
C +CG P+ + +G +G F + + YQC PG++L G S R CL + WSG
Sbjct: 2939 AEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGS 2998
Query: 2731 TPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLP 2790
+P C+P C P +G NG++F+ C G+ L G+S C ++GQWSS P
Sbjct: 2999 SPSCLPCRCSTPVIE-YGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFP 3057
Query: 2791 TCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDR 2850
C +C + NA ++ E+ I Y C+ G+ + GSS L C G+W +
Sbjct: 3058 HCEHTSCGSLPMIPNAFISETSSWKENV-----ITYSCRSGYVIQGSSDLICTEKGVWSQ 3112
Query: 2851 SLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSC-RGSESLIGNDTRVCQEDSHWSGA 2909
P C +SCG P ANAV TGE TY + V C G DT CQ+D W
Sbjct: 3113 PYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRW--- 3169
Query: 2910 LPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSG 2969
P +P C P H GDDF + SC G+ G C L+G+W
Sbjct: 3170 FPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEP 3229
Query: 2970 --LQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWT 3027
C VSCG P +P +G +V S F S++IY C GY+ G R C N W+
Sbjct: 3230 PFSDESCSPVSCGKPESPEHGFVVGSK-YTFESTIIYQCEPGYELEGNRERVCQENRQWS 3288
Query: 3028 GTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWN 3087
G C C P NG + T V Y CN GY +E + A CT++G W+
Sbjct: 3289 GGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEA--HCTENGTWS 3346
Query: 3088 PSKPVCKAVLCPQPPPV-QNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKG 3146
P+CK CP P + +N + +F ++S C +G+ L I++C W
Sbjct: 3347 HPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQ 3406
Query: 3147 EIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQ 3206
+C + CG P G + Y + + C S ++L G R VC +GTW+
Sbjct: 3407 TSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTS-P 3465
Query: 3207 PTCIDPAHNTCPDPG 3221
P C C + G
Sbjct: 3466 PICRAVCRFPCQNGG 3480
Score = 451 bits (1160), Expect = e-126
Identities = 281/929 (30%), Positives = 409/929 (44%), Gaps = 74/929 (7%)
Query: 2453 GSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEF 2512
GSKV+ FC PG+++VG+ C L QW P C+ +SCG+P NG + ++F
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYC----LNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1706
Query: 2513 TLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWR 2572
S V Y+C+ G+ L + C ++G W+ G P+C V ++ + SEH
Sbjct: 1707 YAGSTVTYQCNNGYYLLGDSR--MFCTDNGSWN--GVSPSCLDVDECAVGSDCSEHASCL 1762
Query: 2573 LV------------------------------------SGSLNEYGAQVLLSCSPGYYLE 2596
V SG + GA+V SC GY L
Sbjct: 1763 NVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLM 1822
Query: 2597 GWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLV 2656
G + C +G WN P C+ +SCG + P NG +G+ + CN GYTL
Sbjct: 1823 GVTKITCLESGEWN--HLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLA 1880
Query: 2657 GSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGT 2716
G CLAN WS S C C SP+ I NG G +Y T Y C+ G+ L G
Sbjct: 1881 GDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGP 1940
Query: 2717 SVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSR 2776
S+ C W P C + CG P G+ F + V +TC GY L G+
Sbjct: 1941 SIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDT 2000
Query: 2777 AQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFE--YGMSILYHCKKGFYL 2834
+C ++G+WS C V+C +P V++A PE+ +G Y+C G+ L
Sbjct: 2001 IECLADGKWSRSDQQCLAVSCDEPPIVDHA-------SPETAHRLFGDIAFYYCSDGYSL 2053
Query: 2835 LGSSALTCMANGLW----DRSLPKCLAISCGHPGVPANAVL---TGELFTYGAVVHYSCR 2887
+S L C A G W + +P+C+A C P + ++L + F G+VV + C
Sbjct: 2054 ADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCM 2113
Query: 2888 GSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSC 2947
L + C W+ + P P CG+P + +G G ++ +++ +SC
Sbjct: 2114 EGFVLNTSAKIECMRGGQWNPS-PMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSC 2172
Query: 2948 EMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACW 3007
G ++G + TC G WS P C VSCG P NG + + G +F S V Y C
Sbjct: 2173 NKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCN 2232
Query: 3008 EGYKTSGLMTRHCTANGTWTGTAP-DCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNP 3066
GYK+ G C AN W +P C + CG P + NG G +F V + CN
Sbjct: 2233 PGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNE 2292
Query: 3067 GYVMEAVTSATIRCTKDGRWN-PSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCM 3125
GY E V ++ C K G+WN S P C CP+PP ++N V +++SC
Sbjct: 2293 GY--ELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCK 2350
Query: 3126 DGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEG-RLSGKSFTYKSEVFFQCKS 3184
+G+ L ++L C W P C V C P + + G + + + S V + C
Sbjct: 2351 EGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVG 2410
Query: 3185 PFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRC 3244
F L G+S +CQ DGTWS P C+ CP P GI + +G ST + C
Sbjct: 2411 GFFLRGNSTTLCQPDGTWSSPLPECVPV---ECPQPEEIPNGIID-VQGLAYLSTALYTC 2466
Query: 3245 RKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCH 3304
+ G+ + G+TT C N W G + C C +P+ + DL +G T+ Y+C+
Sbjct: 2467 KPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDL-HYGQTVTYSCN 2525
Query: 3305 PGFFLAGGSEHRTCKADMKWTGKSPVCKS 3333
GF L G S TC W +P C +
Sbjct: 2526 RGFRLEGPSA-LTCLETGDWDVDAPSCNA 2553
Score = 434 bits (1117), Expect = e-121
Identities = 348/1314 (26%), Positives = 512/1314 (38%), Gaps = 155/1314 (11%)
Query: 2101 NSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-APCGYNVTSQNGTIY 2159
+ D G V+ C PG+ L+G+PV C + W P P C+ CG +NG
Sbjct: 1645 SEDLKPGSKVNLFCDPGFQLVGNPVQYCLN--QGQWTQPLPHCERISCGVPPPLENGFHS 1702
Query: 2160 SPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNS---PQLGV 2216
+ F + C +G Y+ L + W+G + + V
Sbjct: 1703 ADDFYAGSTVTYQC--------NNGYYL---LGDSRMFCTDNGSWNGVSPSCLDVDECAV 1751
Query: 2217 FSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDD 2276
S + + + + ++ G + + KC+ P + +
Sbjct: 1752 GSDCSEHASCLNVDGSYICSCVPPYTGDG-----KNCAEPIKCKAPGNPENGH--SSGEI 1804
Query: 2277 FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSP 2336
+ +G V + C GY L+G +TC S ++ +P C+A V G P
Sbjct: 1805 YTVGAEVTFSCQEGYQLMGVTKITCLESG--EWNHLIPYCKA------VSCG------KP 1850
Query: 2337 GYPGN-YFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLL---VVL 2392
P N ++ KV N T +K+ L + S SP + V
Sbjct: 1851 AIPENGCIEELAFTFGSKVTYRCNKGY---TLAGDKESSCLA--NSSWSHSPPVCEPVKC 1905
Query: 2393 SGNHTEQSNFTSRSNQLYL---RWSTDHATSKKGFKI---------RYAAPYCSLTH--- 2437
S + S YL +S D S +G I A P C L
Sbjct: 1906 SSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1965
Query: 2438 -PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSC 2496
P ++ + V Y CK GY + G C L +W C AVSC
Sbjct: 1966 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIEC----LADGKWSRSDQQCLAVSC 2021
Query: 2497 GIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLW-SNKGKP-PTCK 2554
P + S Y C +G+ L + Q +C G W +G+ P C
Sbjct: 2022 DEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQ--LLCNAQGKWVPPEGQDMPRCI 2079
Query: 2555 PVAC---PSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
C PS+ + E VS + G+ V C G+ L + C G WN
Sbjct: 2080 AHFCEKPPSVSYSILES-----VSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNP 2134
Query: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSG 2671
C + CG NG G+ +GA ++CN G+ + G C A G WS
Sbjct: 2135 SPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2194
Query: 2672 SETRCLAGHCGSPDPIVNGHIS-GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQ 2730
C CG P + NG + G + V YQCNPG++ VG+ V +C + W +
Sbjct: 2195 PIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSE 2254
Query: 2731 TP-VCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPL 2789
+P +CVP+ CG P +GF G F + V F CN GY L G S C+ +G+W+
Sbjct: 2255 SPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKS 2314
Query: 2790 -PTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLW 2848
P C C +P +EN + + + E G+ + + CK+G L G S L C+ + W
Sbjct: 2315 NPKCMPAKCPEPPLLENQLVLKEL----TTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQW 2369
Query: 2849 DRSLPKCLAISCGHP-----GVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQED 2903
+ S P C + C P GVP + +G+ V YSC G L GN T +CQ D
Sbjct: 2370 NDSFPVCKIVLCTPPPLISFGVP----IPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPD 2425
Query: 2904 SHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLL 2963
WS LP C P C P +G S ++C+ G +L G+ C
Sbjct: 2426 GTWSSPLPECV---PVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGE 2482
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN 3023
NG W G +P C+A+ C P NG +D + + +V Y+C G++ G C
Sbjct: 2483 NGHWLGGKPTCKAIECLKPKEILNGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLET 2541
Query: 3024 GTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKD 3083
G W AP C I C P + NG G D+++ + Y C PG+ V ++ ++
Sbjct: 2542 GDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGF---QVAGHAMQTCEE 2598
Query: 3084 GRWNPSKPVCKAVLCPQPPPVQNG------------------------------------ 3107
W+ S P C + C PP + G
Sbjct: 2599 SGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVA 2658
Query: 3108 ----------TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCG 3157
S+F +G+ +SY+C GY+L + +L C+ G W G P C+ + C
Sbjct: 2659 KTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECD 2718
Query: 3158 DPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC 3217
P P G L + S V + CK IL GS R+C + WSG P C +C
Sbjct: 2719 LPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRC---EAISC 2775
Query: 3218 PDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR 3277
P G S Y ST+++ C GY + G+ RTC + W + CIP C
Sbjct: 2776 KKPNPVMNGSIKGS-NYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2834
Query: 3278 QPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
P A+ VR D TF + YTC+ GF L G+ R C A+ W+G +P C
Sbjct: 2835 SPPVSANGQVRG-DEYTFQKEIEYTCNEGFLLE-GARSRVCLANGSWSGATPDC 2886
Score = 338 bits (867), Expect = 6e-92
Identities = 219/743 (29%), Positives = 317/743 (42%), Gaps = 82/743 (11%)
Query: 2423 GFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMY 2482
G R A C +P+ NG I + S ++Y C PGY + G TC+ +
Sbjct: 2765 GASPRCEAISCKKPNPVMNGSIKGSNYTYL-STLYYECDPGYVLNGTERRTCQDDK---- 2819
Query: 2483 QWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG 2542
WD P+C V C P NG G+E+T ++ Y C+EGF LE ++ + VC +G
Sbjct: 2820 NWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGAR--SRVCLANG 2877
Query: 2543 LWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLR 2602
WS G P C PV C + QL+ V L G + E V C GY L G L
Sbjct: 2878 SWS--GATPDCVPVRCAT-PPQLANGVTEGLDYGFMKE----VTFHCHEGYILHGAPKLT 2930
Query: 2603 CQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRE 2662
CQ++G W+ E P C+ ++CG +G G ++G + C GY L G+ R
Sbjct: 2931 CQSDGNWDA--EIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRR 2988
Query: 2663 CLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICL 2722
CL+NG WSGS CL C +P I G ++G F QC GF+L+G S C
Sbjct: 2989 CLSNGSWSGSSPSCLPCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCE 3047
Query: 2723 QDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSN 2782
D +WS P C +CG + F + + +V+ ++C +GY++QG S C
Sbjct: 3048 ADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEK 3107
Query: 2783 GQWSSPLPTCRVVNCSDPGFVENAIRHGQQN----------------------------- 2813
G WS P P C ++C P V NA+ G+ +
Sbjct: 3108 GVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDG 3167
Query: 2814 --FPE-----------------------SFEYGMSILYHCKKGFYLLGSSALTCMANGLW 2848
FPE F + C +G+ G + C +G W
Sbjct: 3168 RWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3227
Query: 2849 DR--SLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHW 2906
+ S C +SCG P P + + G +T+ + + Y C L GN RVCQE+ W
Sbjct: 3228 EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQW 3287
Query: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGS 2966
SG + C C P +G ++ T + +SC G+ L G E C NG+
Sbjct: 3288 SGGVAICKETR---CETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGT 3344
Query: 2967 WSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTW 3026
WS P+C+ C P ++S +V C EG+ G C + TW
Sbjct: 3345 WSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETW 3404
Query: 3027 TGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRW 3086
T T+ C ISCG P + N I G + + ++Y C GY++E + C ++G W
Sbjct: 3405 TQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSV--CLENGTW 3462
Query: 3087 NPSKPVCKAVLCPQPPPVQNGTV 3109
S P+C+AV P QNG +
Sbjct: 3463 T-SPPICRAVC---RFPCQNGGI 3481
Score = 320 bits (821), Expect = 1e-86
Identities = 193/636 (30%), Positives = 281/636 (44%), Gaps = 62/636 (9%)
Query: 2743 GNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGF 2802
G+ H T + VN C+ G+ L G C + GQW+ PLP C ++C P
Sbjct: 1636 GSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPP 1695
Query: 2803 VENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCL------ 2856
+EN + F G ++ Y C G+YLLG S + C NG W+ P CL
Sbjct: 1696 LENGFHSA-----DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECA 1750
Query: 2857 -----------------------------------AISCGHPGVPANAVLTGELFTYGAV 2881
I C PG P N +GE++T GA
Sbjct: 1751 VGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAE 1810
Query: 2882 VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKS 2941
V +SC+ L+G C E W+ +P+C + CG P P +G F S
Sbjct: 1811 VTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS---CGKPAIPENGCIEELAFTFGS 1867
Query: 2942 LLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSS 3001
+ + C G+ L G E +CL N SWS PVCE V C +P NG + S G+ + S+
Sbjct: 1868 KVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILS-GLTYLST 1926
Query: 3002 VIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVS 3061
Y+C GY G CTA+G W P C ++ CG+P + + + G +FTF TV+
Sbjct: 1927 ASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVT 1986
Query: 3062 YQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSIS 3121
Y C GY + + TI C DG+W+ S C AV C +PP V + + E + +G
Sbjct: 1987 YTCKEGYTLAGLD--TIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAF 2044
Query: 3122 YSCMDGYQLSHSAILSCEGRGVW----KGEIPQCLPVFCGDPGIPAEGRLSGKS---FTY 3174
Y C DGY L+ ++ L C +G W ++P+C+ FC P + L S F
Sbjct: 2045 YYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAA 2104
Query: 3175 KSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGY 3234
S V F+C F+L S++ C G W+ P I C +P + G + S Y
Sbjct: 2105 GSVVSFKCMEGFVLNTSAKIECMRGGQWNP-SPMSIQCIPVRCGEPPSIMNGYASGS-NY 2162
Query: 3235 EVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPT 3294
G+ V + C KG++I+G TC A WS C P +C +P + +
Sbjct: 2163 SFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRI 2222
Query: 3295 FGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPV 3330
F + Y C+PG + + GS C+A+ W +SP+
Sbjct: 2223 FESEVRYQCNPG-YKSVGSPVFVCQANRHWHSESPL 2257
Score = 284 bits (726), Expect = 1e-75
Identities = 167/581 (28%), Positives = 259/581 (44%), Gaps = 55/581 (9%)
Query: 2797 CSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCL 2856
CSD + ++ H + E + G + C GF L+G+ C+ G W + LP C
Sbjct: 1628 CSDCPRLGGSVPH-LRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCE 1686
Query: 2857 AISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHC--- 2913
ISCG P N + + F G+ V Y C L+G+ C ++ W+G P C
Sbjct: 1687 RISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDV 1746
Query: 2914 ------------------------------TGN-----NPGFCGDPGTPAHGSRLGDDFK 2938
TG+ P C PG P +G G+ +
Sbjct: 1747 DECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYT 1806
Query: 2939 TKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILF 2998
+ + FSC+ G+QL G + TCL +G W+ L P C+AVSCG P P NG I F
Sbjct: 1807 VGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCI-EELAFTF 1865
Query: 2999 SSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNK 3058
S V Y C +GY +G C AN +W+ + P C + C P + NG + T+
Sbjct: 1866 GSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLS 1925
Query: 3059 TVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGS 3118
T SY C+ GY ++ + I CT G W+ + P C V C +PP +++ + G++F + +
Sbjct: 1926 TASYSCDTGYSLQG--PSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRN 1983
Query: 3119 SISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEV 3178
+++Y+C +GY L+ + C G W QCL V C +P I +
Sbjct: 1984 TVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIA 2043
Query: 3179 FFQCKSPFILVGSSRRVCQADGTW----SGIQPTCIDPAHNTCPDPGTPHFGIQN--SSR 3232
F+ C + L +S+ +C A G W P CI AH C P + + I S
Sbjct: 2044 FYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCI--AH-FCEKPPSVSYSILESVSKA 2100
Query: 3233 GYEVGSTVFFRCRKGYHIQGSTTRTCLANLTW--SGIQTECIPHACRQPETPAHADVRAI 3290
+ GS V F+C +G+ + S C+ W S + +CIP C +P + +
Sbjct: 2101 KFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGS 2160
Query: 3291 DLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
+ +FG + Y+C+ GF++ G + TC+A +W+ P C
Sbjct: 2161 NY-SFGAMVAYSCNKGFYIK-GEKKSTCEATGQWSSPIPTC 2199
Score = 203 bits (516), Expect = 3e-51
Identities = 136/451 (30%), Positives = 180/451 (39%), Gaps = 56/451 (12%)
Query: 2920 FCGD----PGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975
FC D G+ H +D K S + C+ G QL G+P + CL G W+ P CE
Sbjct: 1627 FCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCE 1686
Query: 2976 AVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC-- 3033
+SCG P NG S+D S+V Y C GY G CT NG+W G +P C
Sbjct: 1687 RISCGVPPPLENG-FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1745
Query: 3034 ---------------------------------------TIISCGDPGTLANGIQFGTDF 3054
I C PG NG G +
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIY 1805
Query: 3055 TFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDF 3114
T V++ C GY + VT T C + G WN P CKAV C +P +NG +E F
Sbjct: 1806 TVGAEVTFSCQEGYQLMGVTKIT--CLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAF 1863
Query: 3115 RWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTY 3174
+GS ++Y C GY L+ SC W P C PV C P G+ TY
Sbjct: 1864 TFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTY 1923
Query: 3175 KSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT-CPDPGTPHFGIQNSSRG 3233
S + C + + L G S C A G W P C H C +P + +
Sbjct: 1924 LSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC----HLVFCGEPPAIKDAV-ITGNN 1978
Query: 3234 YEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLP 3293
+ +TV + C++GY + G T CLA+ WS +C+ +C +P HA
Sbjct: 1979 FTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAH-R 2037
Query: 3294 TFGYTLVYTCHPGFFLAGGSEHRTCKADMKW 3324
FG Y C G+ LA S+ C A KW
Sbjct: 2038 LFGDIAFYYCSDGYSLADNSQ-LLCNAQGKW 2067
Score = 125 bits (314), Expect = 7e-28
Identities = 78/281 (27%), Positives = 121/281 (43%), Gaps = 45/281 (16%)
Query: 3094 KAVLCPQPP----PVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIP 3149
K++ C P V + D + GS ++ C G+QL + + C +G W +P
Sbjct: 1624 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1683
Query: 3150 QCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
C + CG P G S F S V +QC + + L+G SR C +G+W+G+ P+C
Sbjct: 1684 HCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1743
Query: 3210 ID----------------------------PAHN----------TCPDPGTPHFGIQNSS 3231
+D P + C PG P G +S
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENG-HSSG 1802
Query: 3232 RGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAID 3291
Y VG+ V F C++GY + G T TCL + W+ + C +C +P P + + +
Sbjct: 1803 EIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELA 1862
Query: 3292 LPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
TFG + Y C+ G+ LAG E +C A+ W+ PVC+
Sbjct: 1863 F-TFGSKVTYRCNKGYTLAGDKE-SSCLANSSWSHSPPVCE 1901
Score = 117 bits (293), Expect = 2e-25
Identities = 297/1434 (20%), Positives = 482/1434 (33%), Gaps = 375/1434 (26%)
Query: 142 SHTCGNPGEILKGVLHGT---RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
+H C P + +L +F G + + C+ G++L A + C+ G W+ P
Sbjct: 2080 AHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM----RGGQWN-P 2134
Query: 199 APFCRA--EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLE 256
+P CG P + Y + ++ ++ G +A +
Sbjct: 2135 SPMSIQCIPVRCG----------EPPSIMNGYASGSNYSF------GAMVA-----YSCN 2173
Query: 257 EGYDFL--EISGTEAPSIWLTGMNLPSPVISSK-----NWLRLHFTSDSNHRRKGFNAQF 309
+G+ + S EA W + + PV + N H T + F ++
Sbjct: 2174 KGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG------RIFESEV 2227
Query: 310 QVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVG 369
+ + KS G + + H +S + + V C P +NG G +F VG
Sbjct: 2228 RYQCNPGYKSVGSPVFVCQANRHWHS---ESPLMCVPLDCGKPPPIQNGFMKGENFE-VG 2283
Query: 370 ANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDH-RPICRARTCGSNLRGPSGVITSPNY 428
+ VQF C + Y L G S TCQ+ + W+ P C C P
Sbjct: 2284 SKVQFFCNEGYELVGDSSWTCQKSGK----WNKKSNPKCMPAKC-------------PEP 2326
Query: 429 PVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGS 488
P+ +L +E E G T + + +VL G
Sbjct: 2327 PLLEN------------------QLVLKELTTEVGVVTFSCKEG----------HVLQG- 2357
Query: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLH-G 547
P ++ + +Q W +DS P K V C P + ++G SS LH G
Sbjct: 2358 --PSVLKCLPSQQW-----NDSF--PVCKIVL-------CTPPPLISFGVPIPSSALHFG 2401
Query: 548 DTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGN 607
T+ + C F L G CQ + WS P C + + PEE N
Sbjct: 2402 STVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPEC-------------VPVECPQPEEIPN 2448
Query: 608 NMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASS 667
I + +L + +P F+ +
Sbjct: 2449 G-------IIDVQGLAYLSTALYTCKPGFELV---------------------------- 2473
Query: 668 GHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDG 727
G+ L ++ H G+ T EC P +NG+ G +V++ C+ G
Sbjct: 2474 GNTTTLCGENGHWLGGK------PTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRG 2527
Query: 728 FVKTQGSESITCILQDGNVVWSSTVPRCEA-PCGGHLTASSG-----------VILPPGW 775
F + +G ++TC L+ G+ W P C A C +G +I+ +
Sbjct: 2528 F-RLEGPSALTC-LETGD--WDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCF 2583
Query: 776 PGYY---------KDSLHCEWIIEAKP-----------GHSIKITFDRFQTEVNYDTLEV 815
PG+ ++S I P G K+ D+ E D +EV
Sbjct: 2584 PGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEV 2643
Query: 816 R----DGPASSSPLIGEYHGTQAPQFLISTGNFMY---LLFTTDNSRSSIG--FLIHYES 866
P + + T+ S+ NF+Y + +T + +G LI E
Sbjct: 2644 PYVTPHPPYHLGAVAKTWENTKESPATHSS-NFLYGTMVSYTCNPGYELLGNPVLICQED 2702
Query: 867 VTLESD--SCLD-----PGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ 919
T SC+ P P NG + + S V +SC PG+ L+ + +C N +
Sbjct: 2703 GTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRK 2762
Query: 920 WNHALPSCDALC--------GGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQM 971
W+ A P C+A+ G I+G + T LS + + P
Sbjct: 2763 WSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPG-----------------Y 2805
Query: 972 IFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISY 1031
+ + + D ED PV + V + G F ++ + +
Sbjct: 2806 VLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLL 2865
Query: 1032 EGFNITF---------SEYDLEP--CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEG 1080
EG + D P C P A G +G +TF C GY L G
Sbjct: 2866 EGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHG 2925
Query: 1081 ATKLTCLGGGRRVWSAPLPRC-VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEA 1139
A KLTC G W A +P C CG L+ FP+ + H
Sbjct: 2926 APKLTCQSDGN--WDAEIPLCKPVNCGPPED------LAHGFPNGFSFIH---------- 2967
Query: 1140 GKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNT-N 1198
G H++ +Q F G L +SS R L + + L + +E+ T N
Sbjct: 2968 --GGHIQ---YQCFPGYKLH----GNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVN 3018
Query: 1199 GSDTD----------QGFQLTYTSFDLVKCEDPGIPNYGYR-----------------IR 1231
G+D D +GF+L + CE G + G+ I
Sbjct: 3019 GTDFDCGKAARIQCFKGFKL--LGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFIS 3076
Query: 1232 DEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRIL 1291
+ + + V+ YSC GY + GS+ L C ++ VW +P P C L
Sbjct: 3077 ETSSWKENVITYSCRSGYVIQGSSDLICT--EKGVWSQPYPVC--------------EPL 3120
Query: 1292 SPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSG 1351
S G P N + T H +++E+ L+ + D+D + G
Sbjct: 3121 SCGSPPSVANAV-----------ATGEAH--TYESEVKLRCLEGYTMDTDTDTFTCQKDG 3167
Query: 1352 SALPEDIHSTFNSLTLQFD-SDFFISKSGFSIQFSTSIA--------------------- 1389
PE I + L + + + FS+ S++
Sbjct: 3168 RWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3227
Query: 1390 -----------ATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITC 1432
+C P P++G G T+ +QC+PGY+L+G + C
Sbjct: 3228 EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3281
Score = 108 bits (270), Expect = 9e-23
Identities = 294/1409 (20%), Positives = 479/1409 (33%), Gaps = 253/1409 (17%)
Query: 873 SCLDPGIPVNG---HRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP-SCD 928
SC +P NG H G F S V + C+PGY VC+ N W+ P C
Sbjct: 2203 SCGEPPKVENGFLEHTTGRIF--ESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2260
Query: 929 AL-CG-------GYIQGKS---GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFH 977
L CG G+++G++ G+ + + Y + +WT + S GK +
Sbjct: 2261 PLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKS-GKWNKKSNPKCM 2319
Query: 978 LESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNIT 1037
+ L+ E + V+ + K G + L+ + + +N +
Sbjct: 2320 PAKCPEPPLLENQLVLKELTTEV--GVVTFSCKEGHVLQGPSVLKCLPS-----QQWNDS 2372
Query: 1038 FSEYDLEPCDDPGVPAFSRRI---GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVW 1094
F + C P + +F I HFG ++ +SC G+ L G + C G W
Sbjct: 2373 FPVCKIVLCTPPPLISFGVPIPSSALHFG--STVKYSCVGGFFLRGNSTTLCQPDG--TW 2428
Query: 1095 SAPLPRCV-AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLF 1153
S+PLP CV EC + G + + C E L
Sbjct: 2429 SSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLG 2488
Query: 1154 EGDTLKVYDGKDSSSRPLGTFTKNELL--GLILNSTSNHLWLEFNTNGSDTDQG-FQLTY 1210
T K + G F+ +L + S + LE + + + G + +
Sbjct: 2489 GKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDA 2548
Query: 1211 TSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKP 1270
S + + C+ P G+ + + +++YSC PG+ + G TC + W
Sbjct: 2549 PSCNAIHCDSPQPIENGF-VEGADYSYGAIIIYSCFPGFQVAGHAMQTC---EESGWSSS 2604
Query: 1271 LPSCIA-ECGGQIHAATSGRIL---SPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDT 1326
+P+C+ +CG H GY D+ + ++ P +
Sbjct: 2605 IPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGA-------- 2656
Query: 1327 EMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLT------LQFDSDFFISKSG- 1379
+ K W+ KE + ++ T S T L + + G
Sbjct: 2657 -----VAKTWENT-------KESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGT 2704
Query: 1380 FSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRF 1439
++ + I+ C+ P P+NG G V + C PG+ L G C L NR
Sbjct: 2705 WNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLC--LENRK 2762
Query: 1440 FWQPDPPTCIA-ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFN 1498
W P C A +C G I NY ECD P +V+
Sbjct: 2763 -WSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECD------PGYVL----NGTE 2811
Query: 1499 MEPSYDFLHIYEGE------DSNSPLI---GSYQGSQAP--ERIESSGNSLFL--AFRSD 1545
D + E E D +SP + G +G + + IE + N FL RS
Sbjct: 2812 RRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSR 2871
Query: 1546 ASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITC 1605
+ ++ + C P + NG G D+ +T+ C GY + +TC
Sbjct: 2872 VCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTC 2931
Query: 1606 VIGADGKPSWDQVLPSCN-APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVV 1664
+DG +WD +P C CG + G +P+ ++ F+
Sbjct: 2932 Q--SDG--NWDAEIPLCKPVNCGPPEDLAHG------FPNGFS--------------FIH 2967
Query: 1665 FGQFAYFQTALNDLAELFDG--THAQARLLSSLSGSHSGET---LPLATSNQILLRFSAK 1719
G Y + F G H + +GS SG + LP S ++ +
Sbjct: 2968 GGHIQY---------QCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVN 3018
Query: 1720 S-----GASAR-----GFHFV-------------YQAVPRTSDTQCSSVPEPRYGRRIGS 1756
G +AR GF + P T C S+P S
Sbjct: 3019 GTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP--MIPNAFIS 3076
Query: 1757 EFSAG--SIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTI 1814
E S+ +++ + C GY++QGS+ L C W+ P C P S
Sbjct: 3077 ETSSWKENVITYSCRSGYVIQGSSDLICTEK----GVWSQPYPVCE-PLSCGSPPSVANA 3131
Query: 1815 LSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN--WDSLEIHDGGDVTAPRLGS 1872
++ G Y + + K+ EG + +F +++ W P S
Sbjct: 3132 VATGEAHTYESEV----KLRCLEGYTMDTDTDTFTCQKDGRW------------FPERIS 3175
Query: 1873 FSGTTVPALLNSTSNQLY---LHFQSDISVAAA-GFHLEYKTVGLA-------------- 1914
S P N T ++ +SV+ A G+ E + +
Sbjct: 3176 CSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDES 3235
Query: 1915 ----ACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPL 1970
+C +P P + +G +Y + +QCEPGY L+G C R+W+ +
Sbjct: 3236 CSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQEN--RQWSGGVAI 3293
Query: 1971 CIAT-CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLP-IGYGAHIQFLNFSTEANHDF 2028
C T C L L G D R + P + Y + +S E +
Sbjct: 3294 CKETRCETPLEFLNG-------------KADIENRTTGPNVVYSCN---RGYSLEGPSEA 3337
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQN---RQGFKLAYQAY-- 2083
+NG + + + + +P + + FY D + + R+GF L
Sbjct: 3338 HCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIIT 3397
Query: 2084 --------------ELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2129
E +C P +N Y G +++ CY GY+L G C
Sbjct: 3398 CNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCL 3457
Query: 2130 HGINRNWNYPFPRCDAPCGYNVTSQNGTI 2158
N W P P C A C + QNG I
Sbjct: 3458 E--NGTWTSP-PICRAVCRF--PCQNGGI 3481
Score = 103 bits (257), Expect = 3e-21
Identities = 297/1419 (20%), Positives = 477/1419 (33%), Gaps = 380/1419 (26%)
Query: 1059 GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPL-PRCVAECGASVKGNEGTLL 1117
G +F VG + F C GY L G + TC G+ W+ P+C+ K E LL
Sbjct: 2277 GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK--WNKKSNPKCMP-----AKCPEPPLL 2329
Query: 1118 SPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKN 1177
N + ++ TE G +F EG L+
Sbjct: 2330 E---------NQLVLKELTTEVG------VVTFSCKEGHVLQGPS--------------- 2359
Query: 1178 ELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFT 1237
+L + W + ++ +V C P + ++G I
Sbjct: 2360 -----VLKCLPSQQWND--------------SFPVCKIVLCTPPPLISFGVPIPSSALHF 2400
Query: 1238 DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPA 1297
+ V YSC G+ + G++T C W PLP C+ Q +G I G
Sbjct: 2401 GSTVKYSCVGGFFLRGNSTTLCQPDG--TWSSPLPECVPVECPQPEEIPNGIIDVQGLA- 2457
Query: 1298 PYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDI-----LKVWDGPVDSDILLKEWSGS 1352
T + PG + + E H + K + +IL ++S +
Sbjct: 2458 -----YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYT 2512
Query: 1353 ALPEDIHSTFN---SLTLQFDSDFFISKSG-FSIQFSTSIAATCNDPGMPQNGTRYGDSR 1408
L T++ L+ S ++G + + + A C+ P +NG G
Sbjct: 2513 DLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADY 2572
Query: 1409 EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA-CG-------GNLT--- 1457
G + + C PG+Q+ G A TC + W PTC+ CG G+ T
Sbjct: 2573 SYGAIIIYSCFPGFQVAGHAMQTCEESG----WSSSIPTCMPIDCGLPPHIDFGDCTKLK 2628
Query: 1458 ------GPAGVILSPNYPQPYPP----GKECDW-RVKVNP-----DFVIALIFKSFNMEP 1501
++ Y P+PP W K +P +F+ + S+ P
Sbjct: 2629 DDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMV-SYTCNP 2687
Query: 1502 SYDFLHIYEGEDSNSPLI----GSYQGSQAPERIE------SSGNSLFLAFRSDASVGLS 1551
Y+ L N LI G++ GS AP I ++ + FL F +
Sbjct: 2688 GYELL-------GNPVLICQEDGTWNGS-APSCISIECDLPTAPENGFLRFTETS----M 2735
Query: 1552 GFAIEFKEKPRE--------------------------ACFDPGNIMNGTRVGTDFKLGS 1585
G A+++ KP +C P +MNG+ G+++ S
Sbjct: 2736 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2795
Query: 1586 TITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC-NAPCGGQYTGSEGVVLSPNYPH 1644
T+ Y+CD GY + TC D K +WD+ P C C + G V Y
Sbjct: 2796 TLYYECDPGYVLNGTERRTC---QDDK-NWDEDEPICIPVDCSSPPVSANGQVRGDEY-- 2849
Query: 1645 NYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETL 1704
T KE + N+ L +G ++ L +GS SG
Sbjct: 2850 ------------TFQKE---------IEYTCNE-GFLLEGARSRVCL---ANGSWSG--- 2881
Query: 1705 PLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIV 1764
A P +C++ P+ G G ++ V
Sbjct: 2882 ----------------------------ATPDCVPVRCATPPQLANGVTEGLDYGFMKEV 2913
Query: 1765 RFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYG 1824
F C+ GY+L G+ L CQS N W+ IP C G L+ G+P +
Sbjct: 2914 TFHCHEGYILHGAPKLTCQSDGN----WDAEIPLCKPVNCGPPED-----LAHGFPNGFS 2964
Query: 1825 NNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGT-------- 1876
G IQ Q + ++H GS+SG+
Sbjct: 2965 ----------FIHGGHIQYQC--------FPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 3006
Query: 1877 -TVPALLNSTSN------------QLYLHFQ----SDISVAA-----AGF-HLEYKTVGL 1913
+ P + T N Q + F+ S+I+ A +GF H E+ + G
Sbjct: 3007 CSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCG- 3065
Query: 1914 AACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-I 1972
P +P+ I + N V+++ C GY +QG S + C V W+ P P+C
Sbjct: 3066 ---SLPMIPNAFISETSSWKEN-VITYSCRSGYVIQGSSDLICTEKGV--WSQPYPVCEP 3119
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
+CG S V + G +Y + + ++ GY F+ + +
Sbjct: 3120 LSCGSPPSVANAV--ATGEAHTYESEV----KLRCLEGYTMDTDTDTFTCQ--------K 3165
Query: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQ------ 2086
+G + + LP + TH L+H D S NRQ + Y +
Sbjct: 3166 DGRWFPERISCSPKKCPLPE---NITH-ILVH-GDDFSVNRQVSVSCAEGYTFEGVNISV 3220
Query: 2087 -------------------NCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLT 2127
+C P ++G+++ S Y+ ++ ++C PGY L G+
Sbjct: 3221 CQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERV 3280
Query: 2128 CQHGINRNWN-----YPFPRCDAP--------------CGYNVTSQNGTIYSPGFPDEYP 2168
CQ NR W+ RC+ P G NV YS P E
Sbjct: 3281 CQE--NRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAH 3338
Query: 2169 ILKDCIWLITVP--PGHGVYINFTLLQTEAVND---YIAVWDGPDQNSPQLGVFSGNTAL 2223
++ W VP + + F + + +++ Y+ DQN
Sbjct: 3339 CTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYV------DQN------------- 3379
Query: 2224 ETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKK--CQPPPAVPQAEMLTEDDDFEIGD 2281
+ LL+ H + + + +K C PP V A + ++ GD
Sbjct: 3380 -VSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGD 3436
Query: 2282 FVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQC 2320
+ Y C+ GY L G C + S P C A C
Sbjct: 3437 MITYSCYSGYMLEGFLRSVCLENGTWT---SPPICRAVC 3472
Score = 93.6 bits (231), Expect = 3e-18
Identities = 139/606 (22%), Positives = 222/606 (36%), Gaps = 115/606 (18%)
Query: 1245 CNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLH 1304
C+PG+ + G+ CL+ + W +PLP C +S G P P +N H
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQ--WTQPLPHC--------------ERISCGVPPPLENGFH 1701
Query: 1305 CTWIIEADPGKTISL-----HFIVFDTEMAHDILKVWDGPVDSDILLKEWS-GSALPEDI 1358
A G T++ ++++ D+ M W+G S + + E + GS E
Sbjct: 1702 SADDFYA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSE-- 1757
Query: 1359 HSTFNSLTLQFDSDFFIS----KSGFSIQFSTSIAATCNDPGMPQNGTRYGDSREAGDTV 1414
++ L D + S +G + I C PG P+NG G+ G V
Sbjct: 1758 ----HASCLNVDGSYICSCVPPYTGDGKNCAEPIK--CKAPGNPENGHSSGEIYTVGAEV 1811
Query: 1415 TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIA-ACGGNLTGPAGVILSPNYPQPYP 1473
TF C GYQL G KITC++ W P C A +CG G I +
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGE---WNHLIPYCKAVSCGKPAIPENGCI----EELAFT 1864
Query: 1474 PGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIES 1533
G + +R K + + + + S+SP + +PE I +
Sbjct: 1865 FGSKVTYRCN-----------KGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINN 1913
Query: 1534 SGNSLF-LAFRSDASVGL-SGFAIE------------FKEKPREA----CFDPGNIMNGT 1575
L L + S AS +G++++ + P C +P I +
Sbjct: 1914 GKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAV 1973
Query: 1576 RVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQ-----VLPSCNAPCGGQY 1630
G +F +T+TY C GY + +I C+ ADGK W + + SC+ P +
Sbjct: 1974 ITGNNFTFRNTVTYTCKEGYTLAGLDTIECL--ADGK--WSRSDQQCLAVSCDEPPIVDH 2029
Query: 1631 TGSEGVVLSPNYPHNYTAGQICL------YSITVPKEFVVFGQFAYFQTALNDLAELF-- 1682
SP H G I YS+ + + Q + D+
Sbjct: 2030 A-------SPETAHR-LFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAH 2081
Query: 1683 ---DGTHAQARLLSSLSGSH--SGETLPLATSNQILLRFSAK----SGASARGFHFVYQA 1733
+L S+S + +G + +L SAK G Q
Sbjct: 2082 FCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQC 2141
Query: 1734 VPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWN 1793
+P +C P G GS +S G++V + CN G+ ++G C+ A QW+
Sbjct: 2142 IP----VRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCE----ATGQWS 2193
Query: 1794 DTIPSC 1799
IP+C
Sbjct: 2194 SPIPTC 2199
Score = 92.0 bits (227), Expect = 9e-18
Identities = 55/193 (28%), Positives = 84/193 (43%), Gaps = 5/193 (2%)
Query: 2662 ECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS--YRDTVVYQCNPGFRLVGTSVR 2719
+C+ + S C HC + P NG+ + + + +C+PGF LVG+S+
Sbjct: 359 DCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2720 ICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGS--EFNLNDVVNFTCNTGYLLQGVSRA 2777
+CL + WSG C TC H P HG + S E C+ GY L+G +
Sbjct: 419 LCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKL 478
Query: 2778 QCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLG- 2836
C+ N QW P P C +CS ++ I + ++G C++GF L G
Sbjct: 479 TCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGV 538
Query: 2837 SSALTCMANGLWD 2849
L C +G W+
Sbjct: 539 KEMLRCTTSGKWN 551
Score = 84.7 bits (208), Expect = 1e-15
Identities = 53/180 (29%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 2617 SCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSET 2674
+C ++ C +L P NG I + A C+ G+ LVGS + CL NGLWSGSE+
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 2675 RCLAGHCGSPDPIVNGHISGD--GFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2732
C C +GHIS Y+ T + C+ G+RL G+ C + +W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 2733 VCVPITCGHPGNPAHGFTN-----GSEFNLNDVVNFTCNTGYLLQGVSR-AQCRSNGQWS 2786
CV C P + + +C G++L GV +C ++G+W+
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 83.2 bits (204), Expect = 4e-15
Identities = 117/518 (22%), Positives = 176/518 (33%), Gaps = 99/518 (19%)
Query: 116 SILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGY 175
S LT T D+ V A A++ C +P I G + G ++ G I YSC PG+
Sbjct: 2534 SALTCLETGDWDVDAPSCNAIH-------CDSPQPIENGFVEGADYSYGAIIIYSCFPGF 2586
Query: 176 ILEGHAILTCIVSPGNGASWDFPAPFCRAEGACG-----------------GTLRGTSSS 218
+ GHA+ TC + W P C CG G
Sbjct: 2587 QVAGHAMQTC-----EESGWSSSIPTCMPID-CGLPPHIDFGDCTKLKDDQGYFEQEDDM 2640
Query: 219 ISSPH---FPSEYENNADCTWTILAEPGDTIALVF-----TDFQLEEGYDFL-------E 263
+ P+ P + TW E T + F + GY+ L +
Sbjct: 2641 MEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQ 2700
Query: 264 ISGT---EAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
GT APS +LP+ +LR TS G Q+ K L
Sbjct: 2701 EDGTWNGSAPSCISIECDLPT--APENGFLRFTETS------MGSAVQYSCKPGHILAGS 2752
Query: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNY 380
+++ +N S + C P NG GS+++ + + + + C+ Y
Sbjct: 2753 DLRL------CLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYL-STLYYECDPGY 2805
Query: 381 VLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVW 440
VL G++ TCQ W + PIC C S +G + Y Q E C
Sbjct: 2806 VLNGTERRTCQDDKN----WDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTC-- 2859
Query: 441 VITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYV-------LTGSSVPDL 493
E F LE + + + G T + V L L
Sbjct: 2860 --------------NEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGL 2905
Query: 494 IVSMSNQMWLHLQSDDSI-GSP--------GFKAVYQEIEKGGCGDPGIPAYGKRTGSSF 544
++ H + G+P + A + CG P A+G G SF
Sbjct: 2906 DYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSF 2965
Query: 545 LHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV 582
+HG + ++C ++L G C N WSG+ PSC+
Sbjct: 2966 IHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 3003
Score = 78.6 bits (192), Expect = 1e-13
Identities = 67/233 (28%), Positives = 94/233 (40%), Gaps = 29/233 (12%)
Query: 2899 VCQEDSHWSGA---LPHCTGNNPGFCGDPGTPAHG----SRLGDDFKTKSLLRFSCEMGH 2951
VC+E SG L HC P P +G + + F +R C G
Sbjct: 361 VCREGYRASGQTCELVHCPALKP--------PENGYFIQNTCNNHFNAACGVR--CHPGF 410
Query: 2952 QLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMI-VSSDGILFSSSVIYACWEGY 3010
L GS CL NG WSG + C +C + P +G I S+ +L+ ++ + AC EGY
Sbjct: 411 DLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGY 470
Query: 3011 KTSGLMTRHCTANGTWTGTAPDCTIISCG----DPGTLANGIQFGTDFTFNKTVSY-QCN 3065
+ G C N W G P C C + + G T+ Y C
Sbjct: 471 RLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCR 530
Query: 3066 PGYVMEAVTSATIRCTKDGRWN--PSKPVCKAVLCPQ---PPPVQNGTVEGSD 3113
G+++ V +RCT G+WN VCK V PQ P ++ T+E D
Sbjct: 531 QGFILSGV-KEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQD 582
Score = 78.6 bits (192), Expect = 1e-13
Identities = 140/609 (22%), Positives = 210/609 (34%), Gaps = 104/609 (17%)
Query: 894 STVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGF---PDF 950
S V CDPG+ L + C QW LP C+ + G L GF DF
Sbjct: 1652 SKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGV-----PPPLENGFHSADDF 1706
Query: 951 YPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFS--EPVARLTGSVLPHT 1008
Y S T T + ++G + + T++GS++ P +
Sbjct: 1707 YAGS---TVTYQCNNG----------YYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGS 1753
Query: 1009 IKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSL 1068
+ +I Y G +E C PG P G + VG +
Sbjct: 1754 DCSEHASCLNVDGSYICSCVPPYTGDGKNCAE--PIKCKAPGNPENGHSSGEIYTVGAEV 1811
Query: 1069 TFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVA-ECGASVKGNEGTLLSPNFPSNYDN 1127
TFSC GY+L G TK+TCL G W+ +P C A CG P P N
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGE--WNHLIPYCKAVSCG-----------KPAIPEN--- 1855
Query: 1128 NHECIYKIETEAGKGIHLRTRSFQLFEGD--TLKVYDGKDSSSRPLGTFTKNELLGLILN 1185
CI ++ G + R GD + + + S S P+ K I N
Sbjct: 1856 --GCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINN 1913
Query: 1186 STSNHLWLEF-NTNGSDTDQGFQLTYTSFDLVKCEDPGI----------------PNYGY 1228
L + +T D G+ L S +++C GI P
Sbjct: 1914 GKYILSGLTYLSTASYSCDTGYSLQGPS--IIECTASGIWDRAPPACHLVFCGEPPAIKD 1971
Query: 1229 RIRDEGHFT-DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA----------- 1276
+ +FT V Y+C GY + G +T+ CL+ + W + C+A
Sbjct: 1972 AVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGK--WSRSDQQCLAVSCDEPPIVDH 2029
Query: 1277 ---ECGGQIHAATSGRILSPGYPAPYDNNLHCT----WI-IEADPGKTISLHFIVFDTEM 1328
E ++ + S GY ++ L C W+ E HF +
Sbjct: 2030 ASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSV 2089
Query: 1329 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTF---NSLTLQFDSDFFISKSGFSIQFS 1385
++ IL +S K +GS + F S ++ + S SIQ
Sbjct: 2090 SYSIL-------ESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQ-- 2140
Query: 1386 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
I C +P NG G + G V + C+ G+ ++G+ K TC W
Sbjct: 2141 -CIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQ---WSSPI 2196
Query: 1446 PTC-IAACG 1453
PTC +CG
Sbjct: 2197 PTCHPVSCG 2205
Score = 76.3 bits (186), Expect = 5e-13
Identities = 50/167 (29%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFG-IQNSSRGYEVGST 3239
+C F LVGSS +C +G WSG + C TCP P G I S+R +T
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYC---RVRTCPHLRQPKHGHISCSTREMLYKTT 461
Query: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDL----PTF 3295
C +GY ++GS TC N W G + C+ C + P + + F
Sbjct: 462 CLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKF 521
Query: 3296 GYTLVYTCHPGFFLAGGSEHRTCKADMKWT--GKSPVCKSKGVREVN 3340
G +C GF L+G E C KW ++ VCK ++N
Sbjct: 522 GTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQIN 568
Score = 71.6 bits (174), Expect = 1e-11
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 19/225 (8%)
Query: 2414 STDHATSKKGFKIRYAAPYCSLTH-----PLKNGGILNRTAGA-VGSKVHYFCKPGYRMV 2467
S + ++G+ R + C L H P +NG + T + C PG+ +V
Sbjct: 356 SPEDCVCREGY--RASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLV 413
Query: 2468 GHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNG--SFTGNEFTLDSKVVYECHEG 2525
G S C N L W C+ +C P +G S + E + + C EG
Sbjct: 414 GSSIILCLPNGL----WSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEG 469
Query: 2526 FKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQV 2585
++LE S + T CQ + W G P C C + + + ++G
Sbjct: 470 YRLEGSDKLT--CQGNSQWD--GPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Query: 2586 LLSCSPGYYLEGWR-LLRCQANGTWNIGDERPSCRVISCGSLSFP 2629
+SC G+ L G + +LRC +G WN+G + C+ + ++ P
Sbjct: 526 YVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCP 570
Score = 71.6 bits (174), Expect = 1e-11
Identities = 148/701 (21%), Positives = 242/701 (34%), Gaps = 167/701 (23%)
Query: 1732 QAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQ 1791
Q +P C P G +F AGS V ++CN GY L G + + C
Sbjct: 1680 QPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD----NGS 1735
Query: 1792 WNDTIPSCV--------VPCS--GNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGI 1841
WN PSC+ CS + G+ + P G+ NC + I + G
Sbjct: 1736 WNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCA-EPIKCKAPG- 1793
Query: 1842 QIQVISFATEQNWDSLEIHD-GGDVTAPRLGSF---SGTTVPALLNSTSNQLYLHFQSDI 1897
E S EI+ G +VT + T + L + N L + ++
Sbjct: 1794 -------NPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA-- 1844
Query: 1898 SVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCM 1957
+C +PA+P N + ++++C GYTL G SC+
Sbjct: 1845 ----------------VSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCL 1888
Query: 1958 PGTVRRWNYPSPLC---------------IATCGGTLSTLGGVILSPGFPGSYPNNLDCT 2002
+ W++ P+C G T + G+ P+ ++CT
Sbjct: 1889 ANS--SWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECT 1946
Query: 2003 ----WRISLPIGYGAHIQFL--------------NFS-------------TEANHDFLE- 2030
W + P H+ F NF+ T A D +E
Sbjct: 1947 ASGIWDRAPP---ACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIEC 2003
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETL------IHFY--------SDHSQ---NR 2073
+ +G + S D P + + ET I FY +D+SQ N
Sbjct: 2004 LADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNA 2063
Query: 2074 QGFKLAYQAYELQNC----PDPPPFQNGYMINS----DYSVGQSVSFECYPGYILIGHPV 2125
QG + + ++ C + PP + ++ S ++ G VSF+C G++L
Sbjct: 2064 QGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAK 2123
Query: 2126 LTCQHGINRNWNYPFP--------RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLI 2177
+ C G WN P P RC P +G+ YS G Y K
Sbjct: 2124 IECMRG--GQWN-PSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNK------ 2174
Query: 2178 TVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLG------VFSGNTALETAYSSTN 2231
G YI + ++ + W P + V +G T +
Sbjct: 2175 ------GFYIKG---EKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFES 2225
Query: 2232 QVLLKFHSDFSNGGFFVL------NFHAFQLKKCQP-----PPAVPQAEMLTEDDDFEIG 2280
+V + + + + G V ++H+ C P PP + M + ++FE+G
Sbjct: 2226 EVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFM--KGENFEVG 2283
Query: 2281 DFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCP 2321
V++ C+ GY LVG TC+ S + + + A+CP
Sbjct: 2284 SKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCP 2324
Score = 70.9 bits (172), Expect = 2e-11
Identities = 66/284 (23%), Positives = 108/284 (38%), Gaps = 32/284 (11%)
Query: 3006 CWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCN 3065
C +GY GL CTA P T G PG +++ I + ++
Sbjct: 307 CEKGYYGKGLQYE-CTA-------CPSGTYKPEGSPGGISSCIPCPDE-------NHTSP 351
Query: 3066 PGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTV--EGSDFRWGSSISYS 3123
PG +++ C + S C+ V CP P +NG + + ++
Sbjct: 352 PG------STSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 3124 CMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLS--GKSFTYKSEVFFQ 3181
C G+ L S+I+ C G+W G C C P G +S + YK+
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGYEVGSTV 3240
C + L GS + CQ + W G +P C++ +T P N + + G+
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Query: 3241 FFRCRKGYHIQG-STTRTCLANLTWS-GIQTECIPHACRQPETP 3282
+ CR+G+ + G C + W+ G+Q C+ E P
Sbjct: 526 YVSCRQGFILSGVKEMLRCTTSGKWNVGVQAA----VCKDVEAP 565
Score = 69.7 bits (169), Expect = 5e-11
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 13/196 (6%)
Query: 2720 ICLQDHKWSGQTPVCVPITCGHPGNPAHGF--TNGSEFNLNDVVNFTCNTGYLLQGVSRA 2777
+C + ++ SGQT C + C P +G+ N + N C+ G+ L G S
Sbjct: 361 VCREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 2778 QCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGS 2837
C NG WS CRV C P + H + E Y + L C +G+ L GS
Sbjct: 419 LCLPNGLWSGSESYCRVRTC--PHLRQPKHGHISCSTREML-YKTTCLVACDEGYRLEGS 475
Query: 2838 SALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT-----GELFTYGAVVHYSCRGSESL 2892
LTC N WD P+C+ C +P + +++ + +G + + SCR L
Sbjct: 476 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFIL 535
Query: 2893 IG-NDTRVCQEDSHWS 2907
G + C W+
Sbjct: 536 SGVKEMLRCTTSGKWN 551
Score = 68.9 bits (167), Expect = 8e-11
Identities = 65/252 (25%), Positives = 100/252 (39%), Gaps = 36/252 (14%)
Query: 870 ESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDA 929
E C PG P NGH G + + + VTFSC GY L + C + +WNH +P C A
Sbjct: 1785 EPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1844
Query: 930 L-CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLIT 988
+ CG ++G + F + C ++ K ESS L
Sbjct: 1845 VSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDK-----------ESS---CLAN 1890
Query: 989 EDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYE-GFNI---------TF 1038
S S PV P I G + + L ++S S S + G+++
Sbjct: 1891 SSWSHSPPVCEPVKCSSPENINNGKY--ILSGLTYLSTASYSCDTGYSLQGPSIIECTAS 1948
Query: 1039 SEYDLEP-------CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGR 1091
+D P C +P + G +F +++T++C GY L G + CL G+
Sbjct: 1949 GIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGK 2008
Query: 1092 RVWSAPLPRCVA 1103
WS +C+A
Sbjct: 2009 --WSRSDQQCLA 2018
Score = 68.2 bits (165), Expect = 1e-10
Identities = 68/280 (24%), Positives = 106/280 (37%), Gaps = 65/280 (23%)
Query: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG 932
SC P P +G G + ST+ + C+PGY L + VC+ N QW+ + C
Sbjct: 3240 SCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAIC----- 3294
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGK--------GVQMIFHT---FHLESS 981
C +E +GK G +++ + LE
Sbjct: 3295 --------------------KETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGP 3334
Query: 982 HDYLLITEDGSFSEPV--ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISY---EGFNI 1036
+ TE+G++S PV + +P I ++ F D ++S EGF +
Sbjct: 3335 SE-AHCTENGTWSHPVPLCKPNPCPVPFVIPENAL---LSEKEFYVDQNVSIKCREGFLL 3390
Query: 1037 ----------------TFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEG 1080
T ++ + C P + G H+ GD +T+SC+ GY LEG
Sbjct: 3391 QGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEG 3450
Query: 1081 ATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPN 1120
+ CL G W++P P C A C + N G PN
Sbjct: 3451 FLRSVCLENG--TWTSP-PICRAVCRFPCQ-NGGICQRPN 3486
Score = 67.8 bits (164), Expect = 2e-10
Identities = 60/221 (27%), Positives = 83/221 (37%), Gaps = 41/221 (18%)
Query: 2460 CKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFT--LDSK 2517
C+ GYR G + C+ V C + P NG F N ++
Sbjct: 362 CREGYRASGQT--------------------CELVHCPALKPPENGYFIQNTCNNHFNAA 401
Query: 2518 VVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGS 2577
CH GF L S + +C +GLWS G C+ CP + H+ S S
Sbjct: 402 CGVRCHPGFDLVGS--SIILCLPNGLWS--GSESYCRVRTCPHLRQPKHGHI-----SCS 452
Query: 2578 LNE--YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPN---- 2631
E Y L++C GY LEG L CQ N W+ G E P C C + P +
Sbjct: 453 TREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWD-GPE-PRCVERHCSTFQMPKDVIIS 510
Query: 2632 -GNKIGTLTVYGATAIFTCNTGYTLVG-SHVRECLANGLWS 2670
N +G +C G+ L G + C +G W+
Sbjct: 511 PHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 67.4 bits (163), Expect = 2e-10
Identities = 61/228 (26%), Positives = 86/228 (37%), Gaps = 37/228 (16%)
Query: 372 VQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQ 431
+ +SC YV+QGS + C TE WS P+C +CGS + V T + +
Sbjct: 3086 ITYSCRSGYVIQGSSDLIC---TEK-GVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYE 3141
Query: 432 YEDNAHCVWVITT-TDPDKV------------IKLAFEEFELERGYDTLTV-GDAGKVGD 477
E C+ T TD D I + ++ L + V GD V
Sbjct: 3142 SEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNR 3201
Query: 478 TRSVL----YVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGI 533
SV Y G ++ V + W SD+S CG P
Sbjct: 3202 QVSVSCAEGYTFEGVNIS---VCQLDGTWEPPFSDESCSPVS------------CGKPES 3246
Query: 534 PAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
P +G GS + T+ ++C +EL G R CQ+N QWSG C
Sbjct: 3247 PEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAIC 3294
Score = 65.1 bits (157), Expect = 1e-09
Identities = 59/248 (23%), Positives = 94/248 (37%), Gaps = 33/248 (13%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C PG PENG +G ++ VGA V FSC++ Y L G ITC E W+ P C+
Sbjct: 1789 CKAPGNPENGHSSGEIYT-VGAEVTFSCQEGYQLMGVTKITCLESGE----WNHLIPYCK 1843
Query: 409 ARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGY-DTL 467
A +CG +G I + + C T + LA + + +
Sbjct: 1844 AVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1903
Query: 468 TVGDAGKVGDTRSVLYVLTGSSV-------------PDLIVSMSNQMWLHLQSDDSIGSP 514
+ + + +L LT S P +I ++ +W P
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIW-------DRAPP 1956
Query: 515 GFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQW 574
V+ CG+P TG++F +T+T+ C + L G I C + +W
Sbjct: 1957 ACHLVF-------CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKW 2009
Query: 575 SGNKPSCV 582
S + C+
Sbjct: 2010 SRSDQQCL 2017
Score = 62.0 bits (149), Expect = 1e-08
Identities = 61/228 (26%), Positives = 90/228 (39%), Gaps = 34/228 (14%)
Query: 2774 VSRAQCRSNGQWSSPLPTCRVVNC------SDPGFVENAIRHGQQNFPESFEYGMSILYH 2827
V R R++GQ TC +V+C + F++N + + +
Sbjct: 361 VCREGYRASGQ------TCELVHCPALKPPENGYFIQNTCNN---------HFNAACGVR 405
Query: 2828 CKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVL---TGELFTYGAVVHY 2884
C GF L+GSS + C+ NGLW S C +C H P + + T E+ Y
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREML-YKTTCLV 464
Query: 2885 SCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPG----TPAHGSRLGDDFKTK 2940
+C L G+D CQ +S W G P C + P +P + + F T
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGT- 523
Query: 2941 SLLRFSCEMGHQLRGSPER-TCLLNGSWS-GLQ-PVCEAVSCGNPGTP 2985
+ SC G L G E C +G W+ G+Q VC+ V P
Sbjct: 524 -ICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCP 570
Score = 61.2 bits (147), Expect = 2e-08
Identities = 102/446 (22%), Positives = 152/446 (34%), Gaps = 91/446 (20%)
Query: 524 EKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-- 581
E+ CG P G + F G T+T++C + L+G+ + C N W+G PSC
Sbjct: 1686 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1745
Query: 582 VFSCFFNFTAS--------SGIILSPNYPEEYGNNMNCVWLI-ISEPGS--RIHLIFNDF 630
V C S G + P G+ NC I PG+ H +
Sbjct: 1746 VDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIY 1805
Query: 631 DVEPQFDFLAVKD---DGISDITVLGTFSGNE-VPSQLASSGHIVRLEFQSDHSTTGRGF 686
V + F + G++ IT L + N +P A S
Sbjct: 1806 TVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVS------------------- 1846
Query: 687 NITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNV 746
C P IP NG F GS V++ C+ G+ ES +C+ N
Sbjct: 1847 -----------CGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKES-SCL---ANS 1891
Query: 747 VWSSTVPRCE-APCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQ 805
WS + P CE C ++G + G S C+ G+S++
Sbjct: 1892 SWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCD------TGYSLQ---GPSI 1942
Query: 806 TEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE 865
E + R PA GE A + + TGN T + L +
Sbjct: 1943 IECTASGIWDRAPPACHLVFCGE---PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLD 1999
Query: 866 SVTLESD-------------SCLDPGI-----PVNGHRHGGDFGIRSTVTFSCDPGYTLS 907
++ +D SC +P I P HR GD + C GY+L+
Sbjct: 2000 TIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAF-----YYCSDGYSLA 2054
Query: 908 DDEPLVCERNHQW----NHALPSCDA 929
D+ L+C +W +P C A
Sbjct: 2055 DNSQLLCNAQGKWVPPEGQDMPRCIA 2080
Score = 59.3 bits (142), Expect = 7e-08
Identities = 109/507 (21%), Positives = 168/507 (33%), Gaps = 146/507 (28%)
Query: 697 ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRC- 755
+C P + NG+ GD + + + C++GF+ +G+ S C+ N WS P C
Sbjct: 2832 DCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFL-LEGARSRVCL---ANGSWSGATPDCV 2887
Query: 756 EAPCGGHLTASSGVILPPGWPGYYKD-SLHCE--WIIEAKPGHSIKITFDRFQTEVNYDT 812
C ++GV + G+ K+ + HC +I+ P K+T Q++ N+D
Sbjct: 2888 PVRCATPPQLANGVTEGLDY-GFMKEVTFHCHEGYILHGAP----KLTC---QSDGNWDA 2939
Query: 813 LEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTT-----DNSRSSI--------- 858
P + P HG I G+ Y F ++SR +
Sbjct: 2940 EIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSS 2999
Query: 859 -----------------------------------GF-LIHYESVTLESDSCLDPGIPVN 882
GF L+ +T E+D G P
Sbjct: 3000 PSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC 3059
Query: 883 GHRHGGDFGI-------------RSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDA 929
H G + + +T+SC GY + L+C W+ P C+
Sbjct: 3060 EHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEP 3119
Query: 930 L-CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFH----LESSHDY 984
L CG SP P+ N T E HT+ L Y
Sbjct: 3120 LSCG-----------SP------PSVANAVATGEA----------HTYESEVKLRCLEGY 3152
Query: 985 LLITEDGSFSEPVARLTGSVLPHTI-----KAGLFGNFTAQLRFISDFSI---------- 1029
+ T+ +F+ + G P I K L N T L DFS+
Sbjct: 3153 TMDTDTDTFT---CQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAE 3209
Query: 1030 --SYEGFNIT-----------FSEYDLEP--CDDPGVPAFSRRIGFHFGVGDSLTFSCFL 1074
++EG NI+ FS+ P C P P +G + ++ + C
Sbjct: 3210 GYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEP 3269
Query: 1075 GYRLEGATKLTCLGGGRRVWSAPLPRC 1101
GY LEG + C R WS + C
Sbjct: 3270 GYELEGNRERVC--QENRQWSGGVAIC 3294
Score = 57.4 bits (137), Expect = 3e-07
Identities = 62/266 (23%), Positives = 112/266 (42%), Gaps = 47/266 (17%)
Query: 690 YTTFGQN-----ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDG 744
YT G+N +C PG P NG G+ + +G+ V+F C +G+ + G ITC L+ G
Sbjct: 1776 YTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGY-QLMGVTKITC-LESG 1833
Query: 745 NVVWSSTVPRCEA-PCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDR 803
W+ +P C+A CG +G I + K + C G+++
Sbjct: 1834 E--WNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRC------NKGYTL------ 1879
Query: 804 FQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLL-----FTTDNSRSSI 858
+ ++ + + S SP + E +P+ + N Y+L +T +
Sbjct: 1880 ---AGDKESSCLANSSWSHSPPVCEPVKCSSPE---NINNGKYILSGLTYLSTASYSCDT 1933
Query: 859 GFLIHYESVTLESDS--------------CLDPGIPVNGHRHGGDFGIRSTVTFSCDPGY 904
G+ + S+ + S C +P + G +F R+TVT++C GY
Sbjct: 1934 GYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGY 1993
Query: 905 TLSDDEPLVCERNHQWNHALPSCDAL 930
TL+ + + C + +W+ + C A+
Sbjct: 1994 TLAGLDTIECLADGKWSRSDQQCLAV 2019
Score = 51.2 bits (121), Expect = 2e-05
Identities = 185/905 (20%), Positives = 279/905 (30%), Gaps = 215/905 (23%)
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+CG P + G F G + Y C GY L G + + C + SW+ +P C
Sbjct: 1689 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCT----DNGSWNGVSPSCL 1744
Query: 204 AEGAC---------GGTLRGTSSSISS--PHFPSEYENNAD---CTWTILAEPGDTIALV 249
C L S I S P + + +N A+ C E G + +
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 250 FT-----DFQLEEGYDFLEI-------SGTEAPSI-WLTGMNLPSPVISSKNWL-RLHFT 295
+T F +EGY + + SG I + ++ P I + L FT
Sbjct: 1805 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1864
Query: 296 SDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGS-HKNSVLSQGGVALVSDMCPDPGI 354
S K ++G + K+ S NS S C P
Sbjct: 1865 FGS--------------KVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPEN 1910
Query: 355 PENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGS 414
NG+ S + + + +SC+ Y LQG I C W P C CG
Sbjct: 1911 INNGKYILSGLTYL-STASYSCDTGYSLQGPSIIEC----TASGIWDRAPPACHLVFCGE 1965
Query: 415 NLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFE------LERGYDTLT 468
VIT N+ + C T D + LA ++ L D
Sbjct: 1966 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPP 2025
Query: 469 VGD------AGKVGDTRSVLYVLTGSSVPDLIVSMSNQM--WLHLQSDDSIGSPGFKAVY 520
+ D A ++ + Y G S+ D + N W+ + D P A +
Sbjct: 2026 IVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD---MPRCIAHF 2082
Query: 521 QEIEKGGCGDPGIPAYG---KRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGN 577
C P +Y + + F G ++F+C F L I C + QW+ +
Sbjct: 2083 -------CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 2135
Query: 578 KPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFD 637
S + C+ + EP S I N + +
Sbjct: 2136 PMS----------------------------IQCIPVRCGEPPS----IMNGYASGSNYS 2163
Query: 638 FLA-----------VKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGF 686
F A +K + S G +S S G ++E TTGR F
Sbjct: 2164 FGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIF 2223
Query: 687 --------NITYTTFGQN---------------------ECHDPGIPINGRRFGDRFLLG 717
N Y + G +C P NG G+ F +G
Sbjct: 2224 ESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVG 2283
Query: 718 SSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPG 777
S V F C++G+ + G S TC Q + P+C +P P
Sbjct: 2284 SKVQFFCNEGY-ELVGDSSWTC--QKSGKWNKKSNPKC---------------MPAKCP- 2324
Query: 778 YYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQ---- 833
P ++ TEV T ++G P + + +Q
Sbjct: 2325 -------------EPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWND 2371
Query: 834 ----------APQFLISTG---NFMYLLFTTDNSRSSI-GFLIHYESVTL-ESD------ 872
P LIS G L F + S + GF + S TL + D
Sbjct: 2372 SFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSP 2431
Query: 873 -------SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 925
C P NG ST ++C PG+ L + +C N W P
Sbjct: 2432 LPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKP 2491
Query: 926 SCDAL 930
+C A+
Sbjct: 2492 TCKAI 2496
Score = 51.2 bits (121), Expect = 2e-05
Identities = 106/486 (21%), Positives = 167/486 (34%), Gaps = 91/486 (18%)
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+CG+ I + T + I YSC GY+++G + L C W P P C
Sbjct: 3063 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEK----GVWSQPYPVCE 3118
Query: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
+CG ++ + E E C + DT FT ++G F E
Sbjct: 3119 PL-SCGSPPSVANAVATGEAHTYESEVKLRC---LEGYTMDTDTDTFTC--QKDGRWFPE 3172
Query: 264 ISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVK 323
I + P P +N + D N Q V A GV
Sbjct: 3173 -------RISCSPKKCPLP----ENITHILVHGDDF----SVNRQVSVSCAEGYTFEGVN 3217
Query: 324 MLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQ 383
+ + S + VS C P PE+G GS ++ + + + CE Y L+
Sbjct: 3218 ISVCQLDGTWEPPFSDESCSPVS--CGKPESPEHGFVVGSKYT-FESTIIYQCEPGYELE 3274
Query: 384 GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV------ITSPN--------YP 429
G++ CQ + WS IC+ C + L +G T PN Y
Sbjct: 3275 GNRERVCQENRQ----WSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYS 3330
Query: 430 VQYEDNAHCVWVITTTDPDKVIK---------------LAFEEFELERGYDTLTVGDAGK 474
++ AHC T + P + K L+ +EF +++ V +
Sbjct: 3331 LEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQ-----NVSIKCR 3385
Query: 475 VGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIP 534
G ++L G + I ++ W + + EK CG P
Sbjct: 3386 EG------FLLQGHGI---ITCNPDETWTQTSA--------------KCEKISCGPPAHV 3422
Query: 535 AYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSG 594
G + +GD +T+ C + + L G C +N W+ + P C C F + G
Sbjct: 3423 ENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPICRAVCRFP-CQNGG 3480
Query: 595 IILSPN 600
I PN
Sbjct: 3481 ICQRPN 3486
Score = 50.8 bits (120), Expect = 2e-05
Identities = 149/733 (20%), Positives = 243/733 (33%), Gaps = 174/733 (23%)
Query: 115 GSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNPG-EIL--------------------- 152
G++ W T + + LY + S+TC NPG E+L
Sbjct: 2655 GAVAKTWENTKESPATHSSNFLYGTMVSYTC-NPGYELLGNPVLICQEDGTWNGSAPSCI 2713
Query: 153 -----------KGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
G L T ++G ++YSC PG+IL G + C+ W +P
Sbjct: 2714 SIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCL----ENRKWSGASPR 2769
Query: 202 CRA------EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQL 255
C A G+++G++ + S + YE +PG V +
Sbjct: 2770 CEAISCKKPNPVMNGSIKGSNYTYLSTLY---YE----------CDPG----YVLNGTER 2812
Query: 256 EEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAI 315
D E I ++ SP +S+ +R ++ +K I
Sbjct: 2813 RTCQDDKNWDEDEPICI---PVDCSSPPVSANGQVR--------------GDEYTFQKEI 2855
Query: 316 ELKSRGVKMLPSKDGSHKNSVLSQGGVA-----LVSDMCPDPGIPENGRRAGSDFSRVGA 370
E +L +G+ L+ G + V C P NG G D+ +
Sbjct: 2856 EYTCNEGFLL---EGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFM-K 2911
Query: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCG--SNLRG--PSGVI--- 423
V F C + Y+L G+ +TCQ + W P+C+ CG +L P+G
Sbjct: 2912 EVTFHCHEGYILHGAPKLTCQ----SDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIH 2967
Query: 424 -------TSPNYPVQYEDNAHCV----WVITTTDPDKVIKLAFEEFELERGYDTLTVGDA 472
P Y + + C+ W + + +E G T D
Sbjct: 2968 GGHIQYQCFPGYKLHGNSSRRCLSNGSW---SGSSPSCLPCRCSTPVIEYGTVNGTDFDC 3024
Query: 473 GKVGDTRSVL-YVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD- 530
GK + + L G S I ++ W S GF E CG
Sbjct: 3025 GKAARIQCFKGFKLLGLSE---ITCEADGQW----------SSGF----PHCEHTSCGSL 3067
Query: 531 PGIP-AYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-VFSCFFN 588
P IP A+ T S + +T+ C + + + G + C + WS P C SC
Sbjct: 3068 PMIPNAFISETSS--WKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP 3125
Query: 589 FTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVK----DD 644
+ ++ + + E + C+ + + D P+ + K +
Sbjct: 3126 PSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPE 3185
Query: 645 GISDITVLG-TFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQN------- 696
I+ I V G FS N S + G+ T G NI+
Sbjct: 3186 NITHILVHGDDFSVNRQVSVSCAEGY------------TFEGVNISVCQLDGTWEPPFSD 3233
Query: 697 ------ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSS 750
C P P +G G ++ S++ + C+ G+ + +G+ C N WS
Sbjct: 3234 ESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGY-ELEGNRERVC---QENRQWSG 3289
Query: 751 TV-----PRCEAP 758
V RCE P
Sbjct: 3290 GVAICKETRCETP 3302
Score = 42.4 bits (98), Expect = 0.008
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 1071 SCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPN 1120
+C GYRLEG+ KLTC G + W P PRCV ++ + + ++SP+
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 41.6 bits (96), Expect = 0.014
Identities = 19/56 (33%), Positives = 27/56 (48%)
Query: 545 LHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPN 600
L+ T C + L G +TCQ N+QW G +P CV F +I+SP+
Sbjct: 457 LYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPH 512
Score = 41.2 bits (95), Expect = 0.019
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Query: 2073 RQGFKLAYQAYELQNCPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPVLTC 2128
R+G++ + Q EL +CP P +NGY I + + + C+PG+ L+G ++ C
Sbjct: 363 REGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILC 420
Score = 38.9 bits (89), Expect = 0.092
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 1391 TCNDPGMPQNGTRYGDSREA--GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
TC P++G +RE T CD GY+L+G K+TC Q N++ W P C
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC-QGNSQ--WDGPEPRC 493
Query: 1449 IAACGGNLTGPAGVILSPN 1467
+ P VI+SP+
Sbjct: 494 VERHCSTFQMPKDVIISPH 512
Score = 36.2 bits (82), Expect = 0.60
Identities = 16/53 (30%), Positives = 24/53 (45%)
Query: 893 RSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSP 945
++T +CD GY L + L C+ N QW+ P C Q ++SP
Sbjct: 459 KTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Score = 36.2 bits (82), Expect = 0.60
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 1239 TVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
T L +C+ GY + GS+ LTC + WD P P C+
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCV 494
Score = 35.8 bits (81), Expect = 0.78
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPN 427
+C++ Y L+GS +TCQ ++ W P C R C S + P VI SP+
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQ----WDGPEPRCVERHC-STFQMPKDVIISPH 512
Score = 35.4 bits (80), Expect = 1.0
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 1942 CEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDC 2001
C+ GY L+G ++C + +W+ P P C+ T VI+SP G P
Sbjct: 466 CDEGYRLEGSDKLTCQGNS--QWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGT 523
Query: 2002 TWRISLPIGY 2011
+S G+
Sbjct: 524 ICYVSCRQGF 533
Score = 35.0 bits (79), Expect = 1.3
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 1742 CSSVPEPRYGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
C + +P++G S E + C+ GY L+GS L CQ +QW+ P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQ----GNSQWDGPEPRC 493
Query: 1800 VVPCSGNFTQRRGTILSP 1817
V F + I+SP
Sbjct: 494 VERHCSTFQMPKDVIISP 511
Score = 33.1 bits (74), Expect = 5.1
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 1/66 (1%)
Query: 866 SVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 925
S E SC P N G + +T+SC GY L VC N W + P
Sbjct: 3408 SAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPP 3466
Query: 926 SCDALC 931
C A+C
Sbjct: 3467 ICRAVC 3472
Score = 32.3 bits (72), Expect = 8.6
Identities = 12/28 (42%), Positives = 16/28 (57%)
Query: 554 CPAAFELVGERVITCQQNNQWSGNKPSC 581
C F+LVG +I C N WSG++ C
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYC 433
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 358 bits (920), Expect = 4e-98
Identities = 493/2172 (22%), Positives = 774/2172 (35%), Gaps = 478/2172 (22%)
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL-SGDRRVWDKPLPSCIA 1276
C +P P G +G + + YSC GY + GS++ TC+ SGD +WD P C
Sbjct: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWII--EADPGKTISLHFIVFDTEMAH---- 1330
G T+G +S N H ++ +PG F + +
Sbjct: 164 IPCGLPPTITNGDFISTNR-----ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 1331 -DILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIA 1389
D + +W GP I+ +
Sbjct: 219 DDQVGIWSGPAPQCIIPNK----------------------------------------- 237
Query: 1390 ATCNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPP 1446
C P + +NG D+R + V F+C PG+ ++G ++ C LN W+P+ P
Sbjct: 238 --CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK---WEPELP 291
Query: 1447 TCIAACGGNLTGPAGVILSPNYPQP----YPPGKECDWRVKVNPDFVIALIFKSFNMEPS 1502
+C C P +L Q + PG+E +F ++ EP
Sbjct: 292 SCSRVCQ-----PPPDVLHAERTQRDKDNFSPGQE---------------VF--YSCEPG 329
Query: 1503 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1562
YD + + + QG +P + E K
Sbjct: 330 YDLR-------GAASMRCTPQGDWSP----------------------AAPTCEVK---- 356
Query: 1563 EACFD-PGNIMNGTRV-GTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
+C D G ++NG + + +LG+ + + CD G+++ S+ CV+ A + W+ +P
Sbjct: 357 -SCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL-AGMESLWNSSVP 414
Query: 1621 SCN---APC-----GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ 1672
C P G++TG V +P T C F + G+
Sbjct: 415 VCEQIFCPSPPVIPNGRHTGKPLEV----FPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 470
Query: 1673 TALNDLAELFDGT--------HAQAR---LLSSLSGSHSGETLPLATSNQILLRFSAKSG 1721
T+ ++ H QA L + L + P+ TS L++ +
Sbjct: 471 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTS----LKYECRPE 526
Query: 1722 ASARGFHF-----VYQAVPRT--SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYL 1773
R F + + P+ C + P+P G + ++ GS + + C G+
Sbjct: 527 YYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHR 586
Query: 1774 LQGSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWK 1832
L G ++ C NA A W+ P C +PC T G +S N N +
Sbjct: 587 LIGHSSAECILSGNA-AHWSTKPPICQRIPCGLPPTIANGDFIST-------NRENFHYG 638
Query: 1833 IIVT----EGSGIQ-----IQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLN 1883
+VT GSG + + S N D + I G AP+ + T P + N
Sbjct: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG---PAPQCIIPNKCTPPNVEN 695
Query: 1884 S--TSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ-----EPALPSNSI---------- 1926
S+ L +++ K CQ EP LPS S
Sbjct: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
Query: 1927 -----KIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLS 1980
+ D + + + CEPGY L+G + + C P W+ +P C + +C +
Sbjct: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG--DWSPAAPTCEVKSCDDFMG 813
Query: 1981 TL-GGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTS 2039
L G +L +P NL GA + F+ + F
Sbjct: 814 QLLNGRVL-------FPVNLQL----------GAKVDFV-----CDEGF----------- 840
Query: 2040 PMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYM 2099
Q G+ +L+ + + E CP PP NG
Sbjct: 841 ----QLKGSSASYCVLAGMESL--------------WNSSVPVCEQIFCPSPPVIPNGRH 882
Query: 2100 INSDYSV---GQSVSFECYP------GYILIGHPVLTCQHGINRN--WNYPFPR------ 2142
V G++V++ C P + LIG + C N W+ P PR
Sbjct: 883 TGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGH 942
Query: 2143 CDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIA 2202
C AP + + FP + +C P +G + T L
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECR-----PEYYGRPFSITCLDN-------L 990
Query: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPP 2262
VW P + K C+ P
Sbjct: 991 VWSSPKD-------------------------------------------VCKRKSCKTP 1007
Query: 2263 PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPA 2322
P P M+ D ++G + Y C G+ L+G C LS + P + P
Sbjct: 1008 PD-PVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC 1066
Query: 2323 NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGS 2382
T ++G +S ++ S V T++ GS
Sbjct: 1067 GLPPTIANGDFISTNRENFHYGS------------------VVTYRCNL---------GS 1099
Query: 2383 SGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSL----THP 2438
G+ +V E S + + ++ WS AP C + T P
Sbjct: 1100 RGRKVFELV-----GEPSIYCTSNDDQVGIWSGP-------------APQCIIPNKCTPP 1141
Query: 2439 LKNGGIL---NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
GIL NR+ ++ V + C+PG+ M G C+ + +W+ P C V
Sbjct: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCSRV- 1196
Query: 2496 CGIPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
C P +G T + F+ +V Y C G+ L + A+ C G WS + P
Sbjct: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA--ASLHCTPQGDWSPEA--PR 1252
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGT---W 2609
C +C QL R++ + GA+V C G+ L+G + C G W
Sbjct: 1253 CAVKSCDDFLGQLPHG---RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLW 1309
Query: 2610 NIGDERPSCRVISCGSLSFPPNGNKIGTLT---VYGATAIFTCNTG------YTLVGSHV 2660
N + P C I C + NG GT + YG +TC+ + L+G
Sbjct: 1310 N--NSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
Query: 2661 RECLA----NGLWSGSETRC----LAGHCGSPD--PIVNGHISGDGFSYR--DTVVYQCN 2708
C + NG+WS RC AGHC +P+ P + I + F + ++ Y+C
Sbjct: 1368 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECR 1427
Query: 2709 PGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNT 2767
PG+ S+ CL++ WS C +CG P P +G + ++ VN++CN
Sbjct: 1428 PGYFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNE 1486
Query: 2768 GYLLQGVSRAQCRSNGQ---WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSI 2824
G+ L G C +G W P C +++C P + N + N SF G +
Sbjct: 1487 GFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS--NNRTSFHNGTVV 1544
Query: 2825 LYHCKKG------FYLLGSSALTCMAN----GLWDRSLPKCLAIS-CGHPGVPANAVLTG 2873
Y C G F L+G ++ C + G+W P+C++ + C P V + G
Sbjct: 1545 TYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPG 1604
Query: 2874 E--LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS 2931
FT ++ + C+ ++G+ T CQ + W LPHC+ C P HG
Sbjct: 1605 NRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEILHGE 1660
Query: 2932 RL---GDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGN-PGTPTN 2987
D+F + +SCE + LRG+ C G WS P C SC + G +
Sbjct: 1661 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 1720
Query: 2988 GMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTL 3044
G ++ + + V + C EG++ G HC G W + P C I C +P +
Sbjct: 1721 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAI 1780
Query: 3045 ANGIQFGT---DFTFNKTVSYQCNP----GYVMEAVTSATIRCTKD----GRWNPSKPVC 3093
NG GT D + K +SY C+ G + ++IRCT D G W+ P C
Sbjct: 1781 LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 1840
Query: 3094 KAVL---CPQPPPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGE 3147
+ + CP PP +QNG G S + G +ISY C GY L + C +G+W
Sbjct: 1841 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 1900
Query: 3148 IPQCLPVFCGDP----GIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3203
C V C P GI E + K + Y V +C+ + L GS CQAD W
Sbjct: 1901 DHYCKEVNCSFPLFMNGISKELEMK-KVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWD 1959
Query: 3204 GIQPTCIDPAHN 3215
C H+
Sbjct: 1960 PPLAKCTSRTHD 1971
Score = 350 bits (898), Expect = 1e-95
Identities = 361/1377 (26%), Positives = 540/1377 (39%), Gaps = 220/1377 (15%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
++C +PP NG + + G + + C GY LIG TC G W+ P C
Sbjct: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Query: 2144 D-APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
D PCG T NG S + + + PG G F L+ ++
Sbjct: 162 DRIPCGLPPTITNGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 2198 NDYIAVWDGP-----------DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+D + +W GP N + S N +L +S V + F G
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGP 275
Query: 2247 FVLNFHAFQ---------LKKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
+ A + CQPPP V AE D D+F G V Y C PGY L G
Sbjct: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
+ C + Q + + PTCE + + + +G +L P
Sbjct: 336 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 374
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
N + VD F ++ F G S VL+G + ++ Q+
Sbjct: 375 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQI------- 419
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGA--VGSKVHYFCKP------GYRMVG 2468
+C + NG + G V+Y C P + ++G
Sbjct: 420 ---------------FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 524
Query: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
+ + + C ++ +WS+ CK +C P HVI + +
Sbjct: 525 PEY---YGRPFSITCLDNLVWSS--PKDVCKRKSCKTPPDPVNGMVHVITDI------QV 573
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGT---WNIGDERPSCRVISCGSLSFPPNGNKIGTL 2638
G+++ SC+ G+ L G C +G W+ + P C+ I CG NG+ I T
Sbjct: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWS--TKPPICQRIPCGLPPTIANGDFISTN 631
Query: 2639 TV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPD 2685
YG+ + CN G + LVG C +N G+WSG +C+ + +P
Sbjct: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
Query: 2686 PIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
+ NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 692 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 750
Query: 2743 GNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
+ H + F+ V ++C GY L+G + +C G WS PTC V +C D
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCL 2856
+ +G+ FP + + G + + C +GF L GSSA C+ G LW+ S+P C
Sbjct: 811 ---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Query: 2857 AISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RG-SESLIGNDTRVCQEDSH-- 2905
I C P V N TG E+F +G V+Y+C RG S LIG T C D
Sbjct: 868 QIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGN 927
Query: 2906 --WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRFSCEMGHQLRGS 2956
WS P C G G P H DF + L++ C + G
Sbjct: 928 GVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGR 980
Query: 2957 P-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGL 3015
P TCL N WS + VC+ SC P P NGM+ I S + Y+C G++ G
Sbjct: 981 PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 3016 MTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNKTVSYQCNPG-- 3067
+ C +G W+ P C I CG P T+ANG T +F + V+Y+CN G
Sbjct: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
Query: 3068 --YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGS 3118
V E V +I CT + G W+ P C PP V+NG + + F
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNE 1160
Query: 3119 SISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK---SFTYK 3175
+ + C G+ + + C+ W+ E+P C V C P G + +F+
Sbjct: 1161 VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPG 1219
Query: 3176 SEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD--PGTPHFGIQNSSRG 3233
EVF+ C+ + L G++ C G WS P C A +C D PH G
Sbjct: 1220 QEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC---AVKSCDDFLGQLPH-GRVLFPLN 1275
Query: 3234 YEVGSTVFFRCRKGYHIQGSTTRTCL---ANLTWSGIQTECIPHACRQPETPA-----HA 3285
++G+ V F C +G+ ++GS+ C+ W+ C C P PA H
Sbjct: 1276 LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFC--PNPPAILNGRHT 1333
Query: 3286 DVRAIDLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSPVCK 3332
+ D+P +G + YTC P F L G S R C +D W+ +P C+
Sbjct: 1334 GTPSGDIP-YGKEISYTCDPHPDRGMTFNLIGESTIR-CTSDPHGNGVWSSPAPRCE 1388
Score = 345 bits (885), Expect = 5e-94
Identities = 367/1371 (26%), Positives = 544/1371 (39%), Gaps = 205/1371 (14%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
++C PP NG + + +D VG +++ C G+ LIGH C G +W+ P C
Sbjct: 552 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 2144 DA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
PCG T NG S + + + PG G F L+ ++
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 668
Query: 2198 NDYIAVWDGPDQN----------SPQLGVF-SGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+D + +W GP + + G+ S N +L +S V + F G
Sbjct: 669 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGP 725
Query: 2247 FVLNFHAFQL---------KKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
+ A + CQPPP V AE D D+F G V Y C PGY L G
Sbjct: 726 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 785
Query: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
+ C + Q + + PTCE + + + +G +L P
Sbjct: 786 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 824
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
N + VD F ++ F G S VL+G + ++ Q++
Sbjct: 825 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQIF------ 870
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAV--GSKVHYFCKP------GYRMVG 2468
C + NG + G V+Y C P + ++G
Sbjct: 871 ----------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIG 914
Query: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 915 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 974
Query: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
+ + + C ++ +WS+ CK +C P HVI + GS Y
Sbjct: 975 PEYY---GRPFSITCLDNLVWSSP--KDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 1029
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANG-TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV 2640
SC+ G+ L G C +G T + + P C+ I CG NG+ I T
Sbjct: 1030 ------SCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 1083
Query: 2641 ---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPDPI 2687
YG+ + CN G + LVG C +N G+WSG +C+ + +P +
Sbjct: 1084 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143
Query: 2688 VNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGN 2744
NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 1144 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPE 1202
Query: 2745 PAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPG 2801
HG S F+ V ++C GY L+G + C G WS P C V +C D
Sbjct: 1203 ILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD-- 1260
Query: 2802 FVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAI 2858
+ HG+ FP + + G + + C +GF L GSS C+ G LW+ S+P C I
Sbjct: 1261 -FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1319
Query: 2859 SCGHPGVPANAVLTGEL---FTYGAVVHYSC-----RGSE-SLIGNDTRVCQEDSH---- 2905
C +P N TG YG + Y+C RG +LIG T C D H
Sbjct: 1320 FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGV 1379
Query: 2906 WSGALPHCTGN-NPGFCGDPGTPAHGSR---LGD-DFKTKSLLRFSCEMGHQLRGSPERT 2960
WS P C + G C P S + D +F + L + C G+ +
Sbjct: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-FGKMFSIS 1438
Query: 2961 CLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHC 3020
CL N WS ++ C SCG P P NGM+ + F S+V Y+C EG++ G + C
Sbjct: 1439 CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTC 1498
Query: 3021 TANG---TWTGTAPDCTIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPG----YVM 3070
+G TW AP C IISC P T++NG + T F V+YQC+ G +
Sbjct: 1499 LVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLF 1558
Query: 3071 EAVTSATIRCT-KD---GRWNPSKPVCKAVLCPQPPPVQNG-TVEG--SDFRWGSSISYS 3123
E V +I CT KD G W+ P C + P V+N V G S F I +
Sbjct: 1559 ELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFR 1618
Query: 3124 CMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGRLSGK-SFTYKSEVFFQ 3181
C G+ + S + C+ G W ++P C V P I E LS + +F+ EVF+
Sbjct: 1619 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYS 1678
Query: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD--PGTPHFGIQNSSRGYEVGST 3239
C+ + L G++ C G WS P C +C D PH G ++G+
Sbjct: 1679 CEPSYDLRGAASLHCTPQGDWSPEAPRC---TVKSCDDFLGQLPH-GRVLLPLNLQLGAK 1734
Query: 3240 VFFRCRKGYHIQGSTTRTCL---ANLTWSGIQTECIPHACRQPETPA-----HADVRAID 3291
V F C +G+ ++G + C+ W+ C C P PA H D
Sbjct: 1735 VSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFC--PNPPAILNGRHTGTPFGD 1792
Query: 3292 LPTFGYTLVYTC--HPG----FFLAGGSEHRTCKADMK----WTGKSPVCK 3332
+P +G + Y C HP F L G S R C +D + W+ +P C+
Sbjct: 1793 IP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDPQGNGVWSSPAPRCE 1841
Score = 318 bits (814), Expect = 8e-86
Identities = 301/1077 (27%), Positives = 428/1077 (39%), Gaps = 193/1077 (17%)
Query: 2441 NGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPE 2500
NG + T VGS+++Y C G+R++GHS+A C + + W + P+CQ + CG+P
Sbjct: 562 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPP 620
Query: 2501 SPGNGSFTG---NEFTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGK 2549
+ NG F F S V Y C+ G F+L E S T+ + G+WS G
Sbjct: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS--GP 678
Query: 2550 PPTC-KPVAC--PSIE-----------AQLSEHVIWRLVSG------------SLNEY-- 2581
P C P C P++E L+E V +R G +LN++
Sbjct: 679 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 2582 ------------------------------GAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
G +V SC PGY L G +RC G W+
Sbjct: 739 ELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS- 797
Query: 2612 GDERPSCRVISC---------GSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRE 2662
P+C V SC G + FP N GA F C+ G+ L GS
Sbjct: 798 -PAAPTCEVKSCDDFMGQLLNGRVLFPVN-------LQLGAKVDFVCDEGFQLKGSSASY 849
Query: 2663 CLANG---LWSGSETRCLAGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNP------G 2710
C+ G LW+ S C C SP I NG +G + F + V Y C+P
Sbjct: 850 CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 909
Query: 2711 FRLVGTSVRICLQDHK----WSGQTPVCVPITCGHPGNPAHGF-------TNGSEFNLND 2759
F L+G S C D + WS P C + GH P H TN S+F +
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIGT 967
Query: 2760 VVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFE 2819
+ + C Y + S C N WSSP C+ +C P N + H +
Sbjct: 968 SLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVH----VITDIQ 1022
Query: 2820 YGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVPANAVLTG--- 2873
G I Y C G L+G S+ C+ +G W P C I CG P AN
Sbjct: 1023 VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNR 1082
Query: 2874 ELFTYGAVVHYSC----RGSE--SLIGNDTRVCQEDSH----WSGALPHCTGNNPGFCGD 2923
E F YG+VV Y C RG + L+G + C + WSG P C P C
Sbjct: 1083 ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--IPNKCTP 1140
Query: 2924 PGTPAHGSRLGDD---FKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCG 2980
P +G + D+ F ++ F C+ G ++G C W P C V C
Sbjct: 1141 PNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQ 1198
Query: 2981 NPGTPTNGMIVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISC 3038
P +G S FS V Y+C GY G + HCT G W+ AP C + SC
Sbjct: 1199 PPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSC 1258
Query: 3039 GD-PGTLANG-IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR---WNPSKPVC 3093
D G L +G + F + VS+ C+ G+ ++ S+ C G WN S PVC
Sbjct: 1259 DDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG--SSVSHCVLVGMRSLWNNSVPVC 1316
Query: 3094 KAVLCPQPPPVQNGTVEGS---DFRWGSSISYSCMD------GYQLSHSAILSC----EG 3140
+ + CP PP + NG G+ D +G ISY+C + L + + C G
Sbjct: 1317 EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHG 1376
Query: 3141 RGVWKGEIPQC-LPVFCGDPGIPAEGRLSGKS-------FTYKSEVFFQCKSPFILVGSS 3192
GVW P+C L V G P + + + F + + ++C+ + G
Sbjct: 1377 NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF--GKM 1434
Query: 3193 RRV-CQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQ 3251
+ C + WS ++ C +C P P G+ + + + GSTV + C +G+ +
Sbjct: 1435 FSISCLENLVWSSVEDNC---RRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLI 1491
Query: 3252 GSTTRTCLA---NLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF--GYTLVYTCHPG 3306
GS + TCL N+TW C +C P T ++ D + + +F G + Y CH G
Sbjct: 1492 GSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTG 1551
Query: 3307 ------FFLAG-GSEHRTCKADM--KWTGKSPVCKSKGVREVNETVTKTPVPSDVFF 3354
F L G S + T K D W+ P C S E VP + F
Sbjct: 1552 PDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSF 1608
Score = 315 bits (806), Expect = 7e-85
Identities = 262/902 (29%), Positives = 388/902 (43%), Gaps = 107/902 (11%)
Query: 2511 EFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEH 2568
EF + + + YEC G+ S + + +C ++ +W+ G C+ +C P H
Sbjct: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWT--GAKDRCRRKSCRNPPDPVNGMVH 116
Query: 2569 VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD-ERPSCRVISCGSLS 2627
VI + ++G+Q+ SC+ GY L G C +G I D E P C I CG
Sbjct: 117 VIKGI------QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPP 170
Query: 2628 FPPNGNKIGTLTV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSET 2674
NG+ I T YG+ + CN G + LVG C +N G+WSG
Sbjct: 171 TITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 230
Query: 2675 RCLAGHCGSPDPIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
+C+ + +P + NG + D FS + V ++C PGF + G C +KW +
Sbjct: 231 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL 290
Query: 2732 PVCVPITCGHPGNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSP 2788
P C + C P + H + F+ V ++C GY L+G + +C G WS
Sbjct: 291 PSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPA 349
Query: 2789 LPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-- 2846
PTC V +C D + +G+ FP + + G + + C +GF L GSSA C+ G
Sbjct: 350 APTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 406
Query: 2847 -LWDRSLPKCLAISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGND 2896
LW+ S+P C I C P V N TG E+F +G V+Y+C RG+ LIG
Sbjct: 407 SLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 466
Query: 2897 TRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRF 2945
T C D WS P C G G P H DF + L++
Sbjct: 467 TIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 2946 SCEMGHQLRGSP-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
C + G P TCL N WS + VC+ SC P P NGM+ I S + Y
Sbjct: 522 ECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 3005 ACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNK 3058
+C G++ G + C +G W+ P C I CG P T+ANG T +F +
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGS 639
Query: 3059 TVSYQCNPG----YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVE 3110
V+Y+CNPG V E V +I CT + G W+ P C PP V+NG +
Sbjct: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILV 699
Query: 3111 GSD---FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGR 3166
+ F + + C G+ + + C+ W+ E+P C V P + AE
Sbjct: 700 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERT 759
Query: 3167 LSGK-SFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD-PGTPH 3224
K +F+ EVF+ C+ + L G++ C G WS PTC +C D G
Sbjct: 760 QRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC---EVKSCDDFMGQLL 816
Query: 3225 FGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC-LANL--TWSGIQTECIPHACRQPET 3281
G ++G+ V F C +G+ ++GS+ C LA + W+ C C P
Sbjct: 817 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPV 876
Query: 3282 PAHA--DVRAIDLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSP 3329
+ + +++ FG + YTC P F L G S R C +D + W+ +P
Sbjct: 877 IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR-CTSDPQGNGVWSSPAP 935
Query: 3330 VC 3331
C
Sbjct: 936 RC 937
Score = 301 bits (770), Expect = 1e-80
Identities = 271/971 (27%), Positives = 380/971 (39%), Gaps = 157/971 (16%)
Query: 2441 NGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPE 2500
NG + T VGS+++Y C G+R++GHS+A C + W + P+CQ + CG+P
Sbjct: 1012 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG-NTAHWSTKPPICQRIPCGLPP 1070
Query: 2501 SPGNGSFTGNE---FTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGK 2549
+ NG F F S V Y C+ G F+L E S T+ + G+WS G
Sbjct: 1071 TIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWS--GP 1128
Query: 2550 PPTCK-PVAC--PSIEA-----------QLSEHVIWRLVSG------------SLNEY-- 2581
P C P C P++E L+E V +R G +LN++
Sbjct: 1129 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 2582 ------------------------------GAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
G +V SC PGY L G L C G W+
Sbjct: 1189 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS- 1247
Query: 2612 GDERPSCRVISCGS-LSFPPNGNKIGTLTVY-GATAIFTCNTGYTLVGSHVRECLANG-- 2667
E P C V SC L P+G + L + GA F C+ G+ L GS V C+ G
Sbjct: 1248 -PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR 1306
Query: 2668 -LWSGSETRCLAGHCGSPDPIVNGHISGD---GFSYRDTVVYQCNPG------FRLVGTS 2717
LW+ S C C +P I+NG +G Y + Y C+P F L+G S
Sbjct: 1307 SLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES 1366
Query: 2718 VRICLQDHK----WSGQTPVC-VPITCGHPGNPAH-GFT------NGSEFNLNDVVNFTC 2765
C D WS P C + + GH P F N EF + +N+ C
Sbjct: 1367 TIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYEC 1426
Query: 2766 NTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSIL 2825
GY + S C N WSS CR +C P N + H ++G ++
Sbjct: 1427 RPGYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVH----INTDTQFGSTVN 1481
Query: 2826 YHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVPANAVLTGE---LFTYG 2879
Y C +GF L+GS + TC+ +G WD+ P C ISC P +N F G
Sbjct: 1482 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1541
Query: 2880 AVVHYSCRGSES------LIGNDTRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAH 2929
VV Y C L+G + C WS P C N +
Sbjct: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIR 1601
Query: 2930 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM 2989
F ++RF C+ G + GS C NG W P C V C P +G
Sbjct: 1602 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGE 1660
Query: 2990 IVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGD-PGTLAN 3046
S FS V Y+C Y G + HCT G W+ AP CT+ SC D G L +
Sbjct: 1661 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 1720
Query: 3047 G-IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR---WNPSKPVCKAVLCPQPP 3102
G + + VS+ C+ G+ ++ +++ C G WN S PVC+ + CP PP
Sbjct: 1721 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSAS--HCVLAGMKALWNSSVPVCEQIFCPNPP 1778
Query: 3103 PVQNGTVEGS---DFRWGSSISYSCMDG------YQLSHSAILSC----EGRGVWKGEIP 3149
+ NG G+ D +G ISY+C + L + + C +G GVW P
Sbjct: 1779 AILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAP 1838
Query: 3150 QC---LPVFCGDPGIPAEGRLSG---KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3203
+C +P C P G G + + + C ++LVG C G WS
Sbjct: 1839 RCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWS 1898
Query: 3204 GIQPTCIDPAHNTCPDPGTPHFGIQNS---SRGYEVGSTVFFRCRKGYHIQGSTTRTCLA 3260
+ C + C P + GI + Y G V +C GY ++GS C A
Sbjct: 1899 QLDHYCKEV---NCSFPLFMN-GISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQA 1954
Query: 3261 NLTWSGIQTEC 3271
+ W +C
Sbjct: 1955 DDRWDPPLAKC 1965
Score = 273 bits (698), Expect = 2e-72
Identities = 258/974 (26%), Positives = 391/974 (40%), Gaps = 121/974 (12%)
Query: 2452 VGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGS---FT 2508
+G+ ++Y C+PGY S C +N + W C+ SC P P NG
Sbjct: 65 IGTYLNYECRPGYSGRPFS-IICLKNSV----WTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
Query: 2509 GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG-LWSNKGKPPTCKPVACPSIEAQLSE 2567
G +F S++ Y C +G++L S AT + D +W N + P C + C +
Sbjct: 120 GIQF--GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDN--ETPICDRIPCGLPPTITNG 175
Query: 2568 HVIWRLVSGSLNEYGAQVLLSCSPG------YYLEGWRLLRCQAN----GTWNIGDERPS 2617
I + YG+ V C+PG + L G + C +N G W+ P
Sbjct: 176 DFI--STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS--GPAPQ 231
Query: 2618 CRVISCGSLSFPPNGNKIG---TLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSET 2674
C + + + NG + +L F C G+ + G +C A W
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 291
Query: 2675 RCLAGHCGSPDPIVNGHIS---GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
C + C P +++ + D FS V Y C PG+ L G + C WS
Sbjct: 292 SC-SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAA 350
Query: 2732 PVCVPITC-GHPGNPAHG-FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ---WS 2786
P C +C G +G L V+F C+ G+ L+G S + C G W+
Sbjct: 351 PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWN 410
Query: 2787 SPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCK------KGFYLLGSSAL 2840
S +P C + C P + N G+ E F +G ++ Y C F L+G S +
Sbjct: 411 SSVPVCEQIFCPSPPVIPNGRHTGKP--LEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
Query: 2841 TC----MANGLWDRSLPKCLAISCGHPGVPANAVL-------TGELFTYGAVVHYSCRGS 2889
C NG+W P+C + GH P + + F G + Y CR
Sbjct: 469 RCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR-- 524
Query: 2890 ESLIGNDTRV-CQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS-RLGDDFKTKSLLRFSC 2947
G + C ++ WS C + C P P +G + D + S + +SC
Sbjct: 525 PEYYGRPFSITCLDNLVWSSPKDVCKRKS---CKTPPDPVNGMVHVITDIQVGSRINYSC 581
Query: 2948 EMGHQLRGSPERTCLLNGS---WSGLQPVCEAVSCGNPGTPTNGMIVSS--DGILFSSSV 3002
GH+L G C+L+G+ WS P+C+ + CG P T NG +S+ + + S V
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 641
Query: 3003 IYACWEG------YKTSGLMTRHCTAN----GTWTGTAPDCTIISCGDPGTLANGIQFGT 3052
Y C G ++ G + +CT+N G W+G AP C I + P + NGI
Sbjct: 642 TYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSD 701
Query: 3053 D---FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPV---QN 3106
+ F+ N+ V ++C PG+VM+ ++C +W P P C V C PP V +
Sbjct: 702 NRSLFSLNEVVEFRCQPGFVMKG--PRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAER 758
Query: 3107 GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGD-PGIPAEG 3165
+ +F G + YSC GY L +A + C +G W P C C D G G
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
Query: 3166 R-LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADG---TWSGIQPTCIDPAHNTCPDPG 3221
R L + ++V F C F L GSS C G W+ P C CP P
Sbjct: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC---EQIFCPSPP 875
Query: 3222 TPHFGIQNSSRGYEV---GSTVFFRC------RKGYHIQGSTTRTCLA----NLTWSGIQ 3268
G +++ + EV G V + C + + G +T C + N WS
Sbjct: 876 VIPNG-RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPA 934
Query: 3269 TEC-IPHACRQPETPAHADVR----AIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMK 3323
C I C+ P+ A ++ A D P G +L Y C P ++ G TC ++
Sbjct: 935 PRCGILGHCQAPDHFLFAKLKTQTNASDFP-IGTSLKYECRPEYY--GRPFSITCLDNLV 991
Query: 3324 WTGKSPVCKSKGVR 3337
W+ VCK K +
Sbjct: 992 WSSPKDVCKRKSCK 1005
Score = 208 bits (529), Expect = 9e-53
Identities = 171/643 (26%), Positives = 261/643 (40%), Gaps = 79/643 (12%)
Query: 2750 TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRH 2809
T+ EF + +N+ C GY + S C N W+ CR +C +P N + H
Sbjct: 58 TDEFEFPIGTYLNYECRPGYSGRPFS-IICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVH 116
Query: 2810 GQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVP 2866
+ ++G I Y C KG+ L+GSS+ TC+ +G +WD P C I CG P
Sbjct: 117 ----VIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTI 172
Query: 2867 ANAVLTG---ELFTYGAVVHYSC------RGSESLIGNDTRVCQEDSH----WSGALPHC 2913
N E F YG+VV Y C R L+G + C + WSG P C
Sbjct: 173 TNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Query: 2914 TGNNPGFCGDPGTPAHGSRLGDD---FKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL 2970
P C P +G + D+ F ++ F C+ G ++G C W
Sbjct: 233 I--IPNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 289
Query: 2971 QPVCEAVSCGNPGTPTNGMIVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTG 3028
P C V C P + D FS V Y+C GY G + CT G W+
Sbjct: 290 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
Query: 3029 TAPDCTIISCGD-PGTLANG-IQFGTDFTFNKTVSYQCNPGYVME-AVTSATIRCTKDGR 3085
AP C + SC D G L NG + F + V + C+ G+ ++ + S + +
Sbjct: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
Query: 3086 WNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGSSISYSC------MDGYQLSHSAIL 3136
WN S PVC+ + CP PP + NG G F +G +++Y+C + L + +
Sbjct: 409 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
Query: 3137 SC----EGRGVWKGEIPQC-LPVFCGDPG----IPAEGRLSGKSFTYKSEVFFQCK---- 3183
C +G GVW P+C + C P + + + F + + ++C+
Sbjct: 469 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 528
Query: 3184 -SPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFF 3242
PF + C + WS + C +C P P G+ + +VGS + +
Sbjct: 529 GRPFSI------TCLDNLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 3243 RCRKGYHIQGSTTRTCLAN---LTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGY-- 3297
C G+ + G ++ C+ + WS C C P T A+ D + + F Y
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGS 639
Query: 3298 TLVYTCHPG------FFLAG-GSEHRTCKADMK--WTGKSPVC 3331
+ Y C+PG F L G S + T D W+G +P C
Sbjct: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 115 bits (288), Expect = 8e-25
Identities = 429/2035 (21%), Positives = 677/2035 (33%), Gaps = 470/2035 (23%)
Query: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
KNSV + C +P P NG + G+ +++SC Y L GS S TC
Sbjct: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII 147
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVIT-TTDPDKVI 451
+T+ W + PIC CG +G S N +N H V+T +P
Sbjct: 148 SGDTVI-WDNETPICDRIPCGLPPTITNGDFISTN-----RENFHYGSVVTYRCNPGSGG 201
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
+ FE VG+ I SN DD +
Sbjct: 202 RKVFE-----------LVGEPS--------------------IYCTSN--------DDQV 222
Query: 512 GSPGFKAVYQEIEKGGCGDP----GIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVIT 567
G A Q I C P GI R S F + + F C F + G R +
Sbjct: 223 GIWSGPAP-QCIIPNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVK 279
Query: 568 CQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIF 627
CQ N+W P SC ++ + + N PG +
Sbjct: 280 CQALNKWEPELP----SCSRVCQPPPDVLHAERTQRDKDN---------FSPGQEVF--- 323
Query: 628 NDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFN 687
+ EP +D +R Q D S
Sbjct: 324 --YSCEPGYDLRGAAS---------------------------MRCTPQGDWSPAA---- 350
Query: 688 ITYTTFGQNECHD-PGIPINGR-RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGN 745
T C D G +NGR F LG+ V F CD+GF + +GS + C+L
Sbjct: 351 ---PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGME 406
Query: 746 VVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKP-GHSIKITFDRF 804
+W+S+VP CE + S ++P G H +E P G ++ T D
Sbjct: 407 SLWNSSVPVCE-----QIFCPSPPVIPNG--------RHTGKPLEVFPFGKTVNYTCDPH 453
Query: 805 QTE------VNYDTLEVRDGP------ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTD 852
+ T+ P +S +P G QAP + F L T+
Sbjct: 454 PDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTN 509
Query: 853 NSRSSIGFLIHYE----------SVT-------------LESDSCLDPGIPVNGHRHG-G 888
S IG + YE S+T + SC P PVNG H
Sbjct: 510 ASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT 569
Query: 889 DFGIRSTVTFSCDPGYTL---SDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLS 944
D + S + +SC G+ L S E ++ W+ P C + CG +G +S
Sbjct: 570 DIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 629
Query: 945 PGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVAR--LTG 1002
+F+ S+ T + G G + +F S + + G +S P + +
Sbjct: 630 TNRENFHYGSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 686
Query: 1003 SVLPHTIKAGLFGN-------------FTAQLRFISDFSISYEGFNITFSEYDLEPCDDP 1049
P ++ G+ + F Q F+ + + E +L C
Sbjct: 687 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
Query: 1050 GVP-------AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
P ++R +F G + +SC GY L GA + C G WS P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD--WSPAAPTCE 804
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYD 1162
+ S G LL N ++ + + G + F EG LK
Sbjct: 805 VK---SCDDFMGQLL----------NGRVLFPVNLQLGAKV-----DFVCDEGFQLK--- 843
Query: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPG 1222
G +S L + LW N++ +Q F C P
Sbjct: 844 GSSASYCVL--------------AGMESLW---NSSVPVCEQIF-----------CPSPP 875
Query: 1223 -IPNYGYRIRDEGHFT-DTVVLYSCNP------GYAMHGSNTLTCLSGDR--RVWDKPLP 1272
IPN + + F V Y+C+P + + G +T+ C S + VW P P
Sbjct: 876 VIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 935
Query: 1273 SC--IAECGGQIH---AATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE 1327
C + C H A + + +P C P L +
Sbjct: 936 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL----- 990
Query: 1328 MAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLT-LQFDSDFFIS---------- 1376
VW P D + K S P+ ++ + +T +Q S S
Sbjct: 991 -------VWSSPKD---VCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 1377 ------KSGFSIQFSTS----IAATCNDPGMPQNGTRYGDSRE---AGDTVTFQCDPG-- 1421
SG + +ST C P NG +RE G VT++C+ G
Sbjct: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
Query: 1422 ----YQLQGQAKITCVQLNNRF-FWQPDPPTCIAACGGNLTGP---AGVILS-------- 1465
++L G+ I C +++ W P CI T P G+++S
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDNRSLFSL 1158
Query: 1466 ---------PNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNS 1516
P + P +C K P+ L S +P + LH GE +
Sbjct: 1159 NEVVEFRCQPGFVMKGPRRVKCQALNKWEPE----LPSCSRVCQPPPEILH---GEHT-- 1209
Query: 1517 PLIGSYQGSQAPERIESSGNSLFLA------FRSDASVGLSGFAIEFKEKPR---EACFD 1567
S+Q + +P G +F + R AS+ + E PR ++C D
Sbjct: 1210 ---PSHQDNFSP------GQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
Query: 1568 -PGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC--- 1622
G + +G + +LG+ +++ CD G+++ S CV+ + W+ +P C
Sbjct: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL-VGMRSLWNNSVPVCEHI 1319
Query: 1623 ---NAPC--GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALND 1677
N P G++TG+ S + P+ C F + G+ T+
Sbjct: 1320 FCPNPPAILNGRHTGTP----SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPH 1375
Query: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQIL----------LRFSAKSGASARGF 1727
++ + L + E P A+ + L + + G + F
Sbjct: 1376 GNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMF 1435
Query: 1728 ------HFVYQAV-PRTSDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTA 1779
+ V+ +V C PEP G I ++ GS V + CN G+ L GS +
Sbjct: 1436 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1495
Query: 1780 LHCQSVPNALAQWNDTIPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEG 1838
C N + W+ P C ++ C T G S + + +G
Sbjct: 1496 TTCLVSGNNVT-WDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDG 1554
Query: 1839 SGIQIQVISFATEQNWDSLEIHDGGDVTA---PRLGSFSGTTVPALLNS---TSNQLY-- 1890
Q+ E++ D V + PR S + T P + N+ N+ +
Sbjct: 1555 E----QLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 1891 ----LHFQSDISVAAAGFH-LEYKTVG-----LAACQEPALPSNSIKIG-------DRYM 1933
+ F+ G H ++ +T G L C P I G D +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFS 1670
Query: 1934 VNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLSTL--GGVILSPG 1990
+ + CEP Y L+G + + C P W+ +P C + +C L L G V+L
Sbjct: 1671 PGQEVFYSCEPSYDLRGAASLHCTP--QGDWSPEAPRCTVKSCDDFLGQLPHGRVLL--- 1725
Query: 1991 FPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDL 2050
P NL ++S G ++ A+H L +++S + +
Sbjct: 1726 -----PLNLQLGAKVSFVCDEGFRLK----GRSASHCVLAGMKALWNSSVPVCEQIFCPN 1776
Query: 2051 PAALLSTTH-----------ETLIHFYSDHSQNRQGFKLAYQA----------------- 2082
P A+L+ H + + + H F L ++
Sbjct: 1777 PPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSP 1836
Query: 2083 ---YELQ---NCPDPPPFQNGYMIN---SDYSVGQSVSFECYPGYILIGHPVLTC 2128
EL CP PP QNG+ I S Y G ++S+ C PGY+L+G + C
Sbjct: 1837 APRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFC 1891
Score = 61.2 bits (147), Expect = 2e-08
Identities = 109/468 (23%), Positives = 165/468 (35%), Gaps = 107/468 (22%)
Query: 144 TCGNPGEILKGVLH-GTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+CG P E G++H T G + YSC G+ L G TC+VS GN +WD AP C
Sbjct: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVS-GNNVTWDKKAPIC 1514
Query: 203 RAEGACGGTLRGTSSSISSPHFPS----EYENNADCTWTILAEP-GDTIALVFTDFQLEE 257
+IS+ F S + N T+ P G+ + F+L
Sbjct: 1515 EIISC------EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL------FELVG 1562
Query: 258 GYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
S + +W + P P S N ++ R G + F + + I
Sbjct: 1563 ERSIYCTSKDDQVGVW----SSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRF 1617
Query: 318 KSR-GVKMLPSKDGSHKNSVLSQG--GVAL--VSDMCPDPGIPENGRRAGS--DFSRVGA 370
+ + G M+ GSH + G G L S +C P +G S D G
Sbjct: 1618 RCQPGFVMV----GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQ 1673
Query: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNL-RGPSGVITSPNYP 429
V +SCE +Y L+G+ S+ C + WS P C ++C L + P G + P
Sbjct: 1674 EVFYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP--- 1726
Query: 430 VQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSS 489
L+ G V D G + L G S
Sbjct: 1727 ----------------------------LNLQLGAKVSFVCDEG---------FRLKGRS 1749
Query: 490 VPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSF---LH 546
+++ +W + P + ++ C +P G+ TG+ F +
Sbjct: 1750 ASHCVLAGMKALW-------NSSVPVCEQIF-------CPNPPAILNGRHTGTPFGDIPY 1795
Query: 547 GDTLTFECPA------AFELVGERVITC----QQNNQWSGNKPSCVFS 584
G +++ C F L+GE I C Q N WS P C S
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELS 1843
Score = 58.9 bits (141), Expect = 9e-08
Identities = 104/468 (22%), Positives = 160/468 (34%), Gaps = 113/468 (24%)
Query: 144 TCGNPGEILKGVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+C NP + + G++H + G +I+YSC GY L G + TCI+S G+ WD P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS-GDTVIWDNETPIC 161
Query: 203 RAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF-----TDFQL 255
G +I++ F S N T PG VF
Sbjct: 162 DRIPC------GLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 215
Query: 256 EEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKGFNAQFQ 310
D + I AP + T N+ + ++ S N R + GF +
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 311 VKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGA 370
+ + ++ LPS + V PD E +R +FS G
Sbjct: 276 RRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDNFS-PGQ 320
Query: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPSGVITSP 426
V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 321 EVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG------RV 370
Query: 427 NYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLT 486
+PV + A +F + G+ L
Sbjct: 371 LFPVNLQLGAKV------------------DFVCDEGFQ-------------------LK 393
Query: 487 GSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSS--- 543
GSS +++ +W + P + ++ C P + G+ TG
Sbjct: 394 GSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHTGKPLEV 439
Query: 544 FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
F G T+ + C +F+L+GE I C Q N WS P C
Sbjct: 440 FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 58.9 bits (141), Expect = 9e-08
Identities = 104/474 (21%), Positives = 161/474 (33%), Gaps = 113/474 (23%)
Query: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNAAHWS 605
Query: 197 FPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF---- 250
P C+ G +I++ F S N T PG VF
Sbjct: 606 TKPPICQRIPC------GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 659
Query: 251 -TDFQLEEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKG 304
D + I AP + T N+ + ++ S N R + G
Sbjct: 660 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 719
Query: 305 FNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSD 364
F + + + ++ LPS + V PD E +R +
Sbjct: 720 FVMKGPRRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDN 765
Query: 365 FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPS 420
FS G V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 766 FS-PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG-- 818
Query: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
+PV + A +F + G+
Sbjct: 819 ----RVLFPVNLQLGAKV------------------DFVCDEGFQ--------------- 841
Query: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
L GSS +++ +W + P + ++ C P + G+ T
Sbjct: 842 ----LKGSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHT 883
Query: 541 GSS---FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
G F G + + C +F+L+GE I C Q N WS P C
Sbjct: 884 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 57.4 bits (137), Expect = 3e-07
Identities = 173/825 (20%), Positives = 255/825 (30%), Gaps = 203/825 (24%)
Query: 1241 VLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLPSCIAECGGQIHAATSGRIL-SPGYPAP 1298
V + C+ G+ + GS+ C L G R +W+ +P C A +GR +P P
Sbjct: 1282 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIP 1341
Query: 1299 YDNNLHCTWIIEADPGKTISL--HFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPE 1356
Y + T D G T +L + T H VW P L PE
Sbjct: 1342 YGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGHCKTPE 1400
Query: 1357 DIHSTFNSLTLQF-DSDFFISKS--------GFSIQFSTSIAA--------------TCN 1393
F S T+ D +F + S F FS S +C
Sbjct: 1401 QF--PFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCG 1458
Query: 1394 DPGMPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IAA 1451
P P NG + G TV + C+ G++L G TC+ N W P C I +
Sbjct: 1459 PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIIS 1518
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
C T G S N + G ++ PD
Sbjct: 1519 CEPPPTISNGDFYSNNRTS-FHNGTVVTYQCHTGPD------------------------ 1553
Query: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR----EACFD 1567
G Q E + G D VG+ PR C
Sbjct: 1554 ------------GEQLFELV---GERSIYCTSKDDQVGVWS-----SPPPRCISTNKCTA 1593
Query: 1568 PGNIMNGTRVGTD---FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
P + N RV + F L I ++C G+ ++ ++ C W LP C+
Sbjct: 1594 P-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNG----RWGPKLPHCSR 1648
Query: 1625 PCG-------GQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALND 1677
C G++T S + N++ GQ YS + + G + T D
Sbjct: 1649 VCQPPPEILHGEHTLS--------HQDNFSPGQEVFYSCE--PSYDLRGAASLHCTPQGD 1698
Query: 1678 LAELFDGTHAQARLLSSLSGS--HSGETLPLATSNQILLRFSAKSGASARG---FHFVY- 1731
+ + + G H LPL + F G +G H V
Sbjct: 1699 WSP--EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLA 1756
Query: 1732 -------QAVPRTSDTQCSSVPEPRYGRRIGSEFSA---GSIVRFECNPG------YLLQ 1775
+VP C + P GR G+ F G + + C+ + L
Sbjct: 1757 GMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLI 1816
Query: 1776 GSTALHCQSVPNALAQWNDTIPSCV--VPCS---------GNFTQRRGTILSPGYPEPYG 1824
G +++ C S P W+ P C VP + G++ ++ PG Y
Sbjct: 1817 GESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISY- 1875
Query: 1825 NNLNCIWKIIVTEGSGIQIQVISFATEQN-WDSLEIHDGGDVTAPRLGSFSGTTVPALLN 1883
I G + + F T+Q W L+ H +V + P +N
Sbjct: 1876 ---------ICDPGYLLVGKGFIFCTDQGIWSQLD-HYCKEVNC---------SFPLFMN 1916
Query: 1884 STSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCE 1943
S +L E K V Y D ++ +CE
Sbjct: 1917 GISKEL-----------------EMKKV--------------------YHYGDYVTLKCE 1939
Query: 1944 PGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTL--STLGGVI 1986
GYTL+G C RW+ P C + L TL G I
Sbjct: 1940 DGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDALIVGTLSGTI 1982
Score = 47.8 bits (112), Expect = 2e-04
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNTAHWS 1055
Query: 197 FPAPFCR 203
P C+
Sbjct: 1056 TKPPICQ 1062
Score = 39.3 bits (90), Expect = 0.070
Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 142 SHTCGNPGEILKGV---LHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
S C P EIL G H F+ G ++ YSC PGY L G A L C W
Sbjct: 1194 SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ----GDWSPE 1249
Query: 199 APFC 202
AP C
Sbjct: 1250 APRC 1253
Score = 38.1 bits (87), Expect = 0.16
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 142 SHTCGNPGEILKG---VLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
S C P EIL G + H F+ G ++ YSC P Y L G A L C W
Sbjct: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQ----GDWSPE 1702
Query: 199 APFC 202
AP C
Sbjct: 1703 APRC 1706
Score = 35.8 bits (81), Expect = 0.78
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 389 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 439
Query: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 440 --FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 493
Score = 35.8 bits (81), Expect = 0.78
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 839 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 889
Query: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 890 --FPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 943
Score = 33.5 bits (75), Expect = 3.9
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 15/71 (21%)
Query: 142 SHTCGNPGEILKGVLHGTR-------FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGAS 194
S C P + VLH R F+ G ++ YSC PGY L G A + C
Sbjct: 294 SRVCQPPPD----VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ----GD 345
Query: 195 WDFPAPFCRAE 205
W AP C +
Sbjct: 346 WSPAAPTCEVK 356
Score = 32.7 bits (73), Expect = 6.6
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 10/57 (17%)
Query: 886 HGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC-----DALCGGYIQG 937
H GD+ VT C+ GYTL C+ + +W+ L C DAL G + G
Sbjct: 1929 HYGDY-----VTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSG 1980
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 354 bits (908), Expect = 1e-96
Identities = 361/1371 (26%), Positives = 541/1371 (39%), Gaps = 210/1371 (15%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTCQ-HGINRNWNYPFPRC 2143
++C +PP NG + + G + + C GY LIG TC G W+ P C
Sbjct: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Query: 2144 DA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
D PCG T NG S + + + PG G F L+ ++
Sbjct: 162 DRIPCGLPPTITNGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 2198 NDYIAVWDGPDQN----------SPQLGVF-SGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+D + +W GP + + G+ S N +L +S V + F G
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGP 275
Query: 2247 FVLNFHAFQL---------KKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
+ A + CQPPP V AE D D+F G V Y C PGY L G
Sbjct: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
+ C + Q + + PTCE + + + +G +L P
Sbjct: 336 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 374
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
N + VD F ++ F G S VL+G + ++ Q++
Sbjct: 375 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQIF------ 420
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAV--GSKVHYFCKP------GYRMVG 2468
C + NG + G V+Y C P + ++G
Sbjct: 421 ----------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
Query: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 465 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 524
Query: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
+ + + C ++ +WS+ CK +C P HVI + GS Y
Sbjct: 525 PEYY---GRPFSITCLDNLVWSSP--KDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGT---WNIGDERPSCRVISCGSLSFPPNGNKIGTL 2638
SC+ G+ L G C +G W+ + P C+ I CG NG+ I T
Sbjct: 580 ------SCTTGHRLIGHSSAECILSGNAAHWST--KPPICQRIPCGLPPTIANGDFISTN 631
Query: 2639 TV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPD 2685
YG+ + CN G + LVG C +N G+WSG +C+ + +P
Sbjct: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
Query: 2686 PIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
+ NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 692 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 750
Query: 2743 GNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
+ H + F+ V ++C GY L+G + +C G WS PTC V +C D
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCL 2856
+ +G+ FP + + G + + C +GF L GSSA C+ G LW+ S+P C
Sbjct: 811 ---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
Query: 2857 AISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGNDTRVCQEDSH-- 2905
I C P V N TG E+F +G V+Y+C RG+ LIG T C D
Sbjct: 868 QIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGN 927
Query: 2906 --WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRFSCEMGHQLRGS 2956
WS P C G G P H DF + L++ C + G
Sbjct: 928 GVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GR 980
Query: 2957 P-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGL 3015
P TCL N WS + VC+ SC P P NGM+ I S + Y+C G++ G
Sbjct: 981 PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 3016 MTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNKTVSYQCNPG-- 3067
+ C +G W+ P C I CG P T+ANG T +F + V+Y+CNPG
Sbjct: 1041 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 1100
Query: 3068 --YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGS 3118
V E V +I CT + G W+ P C PP V+NG + + F
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNE 1160
Query: 3119 SISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGRLSGK-SFTYKS 3176
+ + C G+ + + C+ W+ E+P C V P + AE K +F+
Sbjct: 1161 VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQ 1220
Query: 3177 EVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD-PGTPHFGIQNSSRGYE 3235
EVF+ C+ + L G++ C G WS PTC +C D G G +
Sbjct: 1221 EVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQ 1277
Query: 3236 VGSTVFFRCRKGYHIQGSTTRTC-LANL--TWSGIQTECIPHACRQPETPAHA--DVRAI 3290
+G+ V F C +G+ ++GS+ C LA + W+ C C P + + +
Sbjct: 1278 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 1337
Query: 3291 DLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSPVC 3331
++ FG + YTC P F L G S R C +D + W+ +P C
Sbjct: 1338 EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR-CTSDPQGNGVWSSPAPRC 1387
Score = 345 bits (885), Expect = 5e-94
Identities = 367/1371 (26%), Positives = 544/1371 (39%), Gaps = 205/1371 (14%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
++C PP NG + + +D VG +++ C G+ LIGH C G +W+ P C
Sbjct: 1002 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 1061
Query: 2144 DA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
PCG T NG S + + + PG G F L+ ++
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 1118
Query: 2198 NDYIAVWDGPDQN----------SPQLGVF-SGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+D + +W GP + + G+ S N +L +S V + F G
Sbjct: 1119 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGP 1175
Query: 2247 FVLNFHAFQL---------KKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
+ A + CQPPP V AE D D+F G V Y C PGY L G
Sbjct: 1176 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 1235
Query: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
+ C + Q + + PTCE + + + +G +L P
Sbjct: 1236 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 1274
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
N + VD F ++ F G S VL+G + ++ Q++
Sbjct: 1275 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQIF------ 1320
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAV--GSKVHYFCKP------GYRMVG 2468
C + NG + G V+Y C P + ++G
Sbjct: 1321 ----------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIG 1364
Query: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 1365 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 1424
Query: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
+ + + C ++ +WS+ CK +C P HVI + GS Y
Sbjct: 1425 PEYY---GRPFSITCLDNLVWSSP--KDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 1479
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANG-TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV 2640
SC+ G+ L G C +G T + + P C+ I CG NG+ I T
Sbjct: 1480 ------SCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 1533
Query: 2641 ---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPDPI 2687
YG+ + CN G + LVG C +N G+WSG +C+ + +P +
Sbjct: 1534 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1593
Query: 2688 VNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGN 2744
NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 1594 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPE 1652
Query: 2745 PAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPG 2801
HG S F+ V ++C GY L+G + C G WS P C V +C D
Sbjct: 1653 ILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD-- 1710
Query: 2802 FVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAI 2858
+ HG+ FP + + G + + C +GF L GSS C+ G LW+ S+P C I
Sbjct: 1711 -FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1769
Query: 2859 SCGHPGVPANAVLTGEL---FTYGAVVHYSC-----RGSE-SLIGNDTRVCQEDSH---- 2905
C +P N TG YG + Y+C RG +LIG T C D H
Sbjct: 1770 FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGV 1829
Query: 2906 WSGALPHCTGN-NPGFCGDPGTPAHGSR---LGD-DFKTKSLLRFSCEMGHQLRGSPERT 2960
WS P C + G C P S + D +F + L + C G+ +
Sbjct: 1830 WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-FGKMFSIS 1888
Query: 2961 CLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHC 3020
CL N WS ++ C SCG P P NGM+ + F S+V Y+C EG++ G + C
Sbjct: 1889 CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTC 1948
Query: 3021 TANG---TWTGTAPDCTIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPG----YVM 3070
+G TW AP C IISC P T++NG + T F V+YQC+ G +
Sbjct: 1949 LVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLF 2008
Query: 3071 EAVTSATIRCT-KD---GRWNPSKPVCKAVLCPQPPPVQNG-TVEG--SDFRWGSSISYS 3123
E V +I CT KD G W+ P C + P V+N V G S F I +
Sbjct: 2009 ELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFR 2068
Query: 3124 CMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGRLSGK-SFTYKSEVFFQ 3181
C G+ + S + C+ G W ++P C V P I E LS + +F+ EVF+
Sbjct: 2069 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYS 2128
Query: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD--PGTPHFGIQNSSRGYEVGST 3239
C+ + L G++ C G WS P C +C D PH G ++G+
Sbjct: 2129 CEPSYDLRGAASLHCTPQGDWSPEAPRC---TVKSCDDFLGQLPH-GRVLLPLNLQLGAK 2184
Query: 3240 VFFRCRKGYHIQGSTTRTCL---ANLTWSGIQTECIPHACRQPETPA-----HADVRAID 3291
V F C +G+ ++G + C+ W+ C C P PA H D
Sbjct: 2185 VSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFC--PNPPAILNGRHTGTPFGD 2242
Query: 3292 LPTFGYTLVYTC--HPG----FFLAGGSEHRTCKADMK----WTGKSPVCK 3332
+P +G + Y C HP F L G S R C +D + W+ +P C+
Sbjct: 2243 IP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDPQGNGVWSSPAPRCE 2291
Score = 344 bits (883), Expect = 8e-94
Identities = 458/1990 (23%), Positives = 719/1990 (36%), Gaps = 422/1990 (21%)
Query: 1392 CNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C P + +NG D+R + V F+C PG+ ++G ++ C LN W+P+ P+C
Sbjct: 688 CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK---WEPELPSC 743
Query: 1449 IAACGGNLTGPAGVILSPNYPQP----YPPGKECDWRVKVNPDFVIALIFKSFNMEPSYD 1504
C P +L Q + PG+E +F ++ EP YD
Sbjct: 744 SRVCQ-----PPPDVLHAERTQRDKDNFSPGQE---------------VF--YSCEPGYD 781
Query: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREA 1564
+ + + QG +P + E K +
Sbjct: 782 LR-------GAASMRCTPQGDWSP----------------------AAPTCEVK-----S 807
Query: 1565 CFD-PGNIMNGTRV-GTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
C D G ++NG + + +LG+ + + CD G+++ S+ CV+ A + W+ +P C
Sbjct: 808 CDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL-AGMESLWNSSVPVC 866
Query: 1623 N---APC-----GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTA 1674
P G++TG V +P T C F + G+ T+
Sbjct: 867 EQIFCPSPPVIPNGRHTGKPLEV----FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 922
Query: 1675 LNDLAELFDGT--------HAQAR---LLSSLSGSHSGETLPLATSNQILLRFSAKSGAS 1723
++ H QA L + L + P+ TS L++ +
Sbjct: 923 DPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTS----LKYECRPEYY 978
Query: 1724 ARGFHF-----VYQAVPRT--SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQ 1775
R F + + P+ C + P+P G + ++ GS + + C G+ L
Sbjct: 979 GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI 1038
Query: 1776 GSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKII 1834
G ++ C NA A W+ P C +PC T G +S N N + +
Sbjct: 1039 GHSSAECILSGNA-AHWSTKPPICQRIPCGLPPTIANGDFIST-------NRENFHYGSV 1090
Query: 1835 VT----EGSGIQ-----IQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNS- 1884
VT GSG + + S N D + I G AP+ + T P + N
Sbjct: 1091 VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG---PAPQCIIPNKCTPPNVENGI 1147
Query: 1885 -TSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ-----EPALPSNSI------------ 1926
S+ L +++ K CQ EP LPS S
Sbjct: 1148 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAE 1207
Query: 1927 ---KIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLSTL 1982
+ D + + + CEPGY L+G + + C P W+ +P C + +C + L
Sbjct: 1208 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG--DWSPAAPTCEVKSCDDFMGQL 1265
Query: 1983 -GGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPM 2041
G +L +P NL GA + F+ + F
Sbjct: 1266 LNGRVL-------FPVNLQL----------GAKVDFV-----CDEGF------------- 1290
Query: 2042 IGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMIN 2101
Q G+ +L+ + + E CP PP NG
Sbjct: 1291 --QLKGSSASYCVLAGMESL--------------WNSSVPVCEQIFCPSPPVIPNGRHTG 1334
Query: 2102 SDYSV---GQSVSFECYP------GYILIGHPVLTCQHGINRN--WNYPFPR------CD 2144
V G++V++ C P + LIG + C N W+ P PR C
Sbjct: 1335 KPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ 1394
Query: 2145 APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVW 2204
AP + + FP + +C P +G + T L VW
Sbjct: 1395 APDHFLFAKLKTQTNASDFPIGTSLKYECR-----PEYYGRPFSITCLDN-------LVW 1442
Query: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPA 2264
P + K C+ PP
Sbjct: 1443 SSPKD-------------------------------------------VCKRKSCKTPPD 1459
Query: 2265 VPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANE 2324
P M+ D ++G + Y C G+ L+G C LS + P + P
Sbjct: 1460 -PVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGL 1518
Query: 2325 VRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSG 2384
T ++G +S ++ S V T++ GS G
Sbjct: 1519 PPTIANGDFISTNRENFHYGS------------------VVTYRCNL---------GSRG 1551
Query: 2385 QSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSL----THPLK 2440
+ +V E S + + ++ WS AP C + T P
Sbjct: 1552 RKVFELV-----GEPSIYCTSNDDQVGIWSGP-------------APQCIIPNKCTPPNV 1593
Query: 2441 NGGIL---NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCG 2497
GIL NR+ ++ V + C+PG+ M G C+ + +W+ P C V C
Sbjct: 1594 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCSRV-CQ 1648
Query: 2498 IPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCK 2554
P +G T + F+ +V Y C G+ L + A+ C G WS + P C
Sbjct: 1649 PPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA--ASLHCTPQGDWSPEA--PRCA 1704
Query: 2555 PVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGT---WNI 2611
+C QL R++ + GA+V C G+ L+G + C G WN
Sbjct: 1705 VKSCDDFLGQLPHG---RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWN- 1760
Query: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLT---VYGATAIFTCNTG------YTLVGSHVRE 2662
+ P C I C + NG GT + YG +TC+ + L+G
Sbjct: 1761 -NSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1819
Query: 2663 CLA----NGLWSGSETRC----LAGHCGSPD--PIVNGHISGDGFSYR--DTVVYQCNPG 2710
C + NG+WS RC AGHC +P+ P + I + F + ++ Y+C PG
Sbjct: 1820 CTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPG 1879
Query: 2711 FRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTGY 2769
+ S+ CL++ WS C +CG P P +G + ++ VN++CN G+
Sbjct: 1880 YFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGF 1938
Query: 2770 LLQGVSRAQCRSNGQ---WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILY 2826
L G C +G W P C +++C P + N + N SF G + Y
Sbjct: 1939 RLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS--NNRTSFHNGTVVTY 1996
Query: 2827 HCKKG------FYLLGSSALTCMAN----GLWDRSLPKCLAIS-CGHPGVPANAVLTGE- 2874
C G F L+G ++ C + G+W P+C++ + C P V + G
Sbjct: 1997 QCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNR 2056
Query: 2875 -LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRL 2933
FT ++ + C+ ++G+ T CQ + W LPHC+ C P HG
Sbjct: 2057 SFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEILHGEHT 2112
Query: 2934 ---GDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGN-PGTPTNGM 2989
D+F + +SCE + LRG+ C G WS P C SC + G +G
Sbjct: 2113 LSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGR 2172
Query: 2990 IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTLAN 3046
++ + + V + C EG++ G HC G W + P C I C +P + N
Sbjct: 2173 VLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILN 2232
Query: 3047 GIQFGT---DFTFNKTVSYQCNP----GYVMEAVTSATIRCTKD----GRWNPSKPVCKA 3095
G GT D + K +SY C+ G + ++IRCT D G W+ P C+
Sbjct: 2233 GRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL 2292
Query: 3096 VL---CPQPPPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIP 3149
+ CP PP +QNG G S + G +ISY C GY L + C +G+W
Sbjct: 2293 SVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDH 2352
Query: 3150 QCLPVFCGDP----GIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGI 3205
C V C P GI E + K + Y V +C+ + L GS CQAD W
Sbjct: 2353 YCKEVNCSFPLFMNGISKELEMK-KVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPP 2411
Query: 3206 QPTCIDPAHN 3215
C H+
Sbjct: 2412 LAKCTSRTHD 2421
Score = 323 bits (828), Expect = 2e-87
Identities = 284/982 (28%), Positives = 414/982 (42%), Gaps = 121/982 (12%)
Query: 2441 NGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPE 2500
NG + T VGS+++Y C G+R++GHS+A C + + W + P+CQ + CG+P
Sbjct: 562 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPP 620
Query: 2501 SPGNGSFTG---NEFTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGK 2549
+ NG F F S V Y C+ G F+L E S T+ + G+WS G
Sbjct: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS--GP 678
Query: 2550 PPTC-KPVAC--PSIEAQLSEHVIWRLVSG--SLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2604
P C P C P++E + LVS SL V C PG+ ++G R ++CQ
Sbjct: 679 APQCIIPNKCTPPNVENGI-------LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
Query: 2605 ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY-------GATAIFTCNTGYTLVG 2657
A W E P SC + PP T G ++C GY L G
Sbjct: 732 ALNKWE--PELP-----SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 784
Query: 2658 SHVRECLANGLWSGSETRCLAGHCGS-PDPIVNGHISGD-GFSYRDTVVYQCNPGFRLVG 2715
+ C G WS + C C ++NG + V + C+ GF+L G
Sbjct: 785 AASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKG 844
Query: 2716 TSVRICL---QDHKWSGQTPVCVPITCGHPGNPAHGFTNGSE---FNLNDVVNFTCN--- 2766
+S C+ + W+ PVC I C P +G G F VN+TC+
Sbjct: 845 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHP 904
Query: 2767 ---TGYLLQGVSRAQCRS----NGQWSSPLPTCRVV-NCSDPGFVENAIRHGQQNFPESF 2818
T + L G S +C S NG WSSP P C ++ +C P A Q N F
Sbjct: 905 DRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTN-ASDF 963
Query: 2819 EYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANA---VLTGEL 2875
G S+ Y C+ +Y S +TC+ N +W C SC P P N V+T
Sbjct: 964 PIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD-- 1020
Query: 2876 FTYGAVVHYSCRGSESLIGNDTRVC---QEDSHWSGALPHCTGNNPGFCGDPGTPAHGSR 2932
G+ ++YSC LIG+ + C +HWS P C CG P T A+G
Sbjct: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIP---CGLPPTIANGDF 1077
Query: 2933 LG---DDFKTKSLLRFSCEMG------HQLRGSPERTCLLN----GSWSGLQPVCEAVSC 2979
+ ++F S++ + C G +L G P C N G WSG P C +
Sbjct: 1078 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
Query: 2980 GNPGTPTNGMIVSSDGILFSSS--VIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIIS 3037
P NG++VS + LFS + V + C G+ G C A W P C+ +
Sbjct: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
Query: 3038 CGDPGTL-ANGIQFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKA 3095
P L A Q D F+ + V Y C PGY + +A++RCT G W+P+ P C+
Sbjct: 1198 QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWSPAAPTCEV 1255
Query: 3096 VLCPQ-PPPVQNGTV-EGSDFRWGSSISYSCMDGYQLSHSAILSCEGRG---VWKGEIPQ 3150
C + NG V + + G+ + + C +G+QL S+ C G +W +P
Sbjct: 1256 KSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV 1315
Query: 3151 CLPVFCGDPGIPAEGRLSGKS---FTYKSEVFFQCK------SPFILVGSSRRVC----Q 3197
C +FC P + GR +GK F + V + C + F L+G S C Q
Sbjct: 1316 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 1375
Query: 3198 ADGTWSGIQPTCIDPAHNTCPDPGTPHF-----GIQNSSRGYEVGSTVFFRCRKGYHIQG 3252
+G WS P C H PD HF Q ++ + +G+++ + CR Y+ +
Sbjct: 1376 GNGVWSSPAPRCGILGHCQAPD----HFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP 1431
Query: 3253 STTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGG 3312
+ TCL NL WS + C +C+ P P + V I G + Y+C G L G
Sbjct: 1432 FSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1490
Query: 3313 SEHRTCKA--DMKWTGKSPVCK 3332
S + W+ K P+C+
Sbjct: 1491 SSAECILSGNTAHWSTKPPICQ 1512
Score = 320 bits (821), Expect = 1e-86
Identities = 282/970 (29%), Positives = 408/970 (42%), Gaps = 121/970 (12%)
Query: 2453 GSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTG--- 2509
GS++ Y C GYR++G S+ATC + WD+ TP+C + CG+P + NG F
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISG-DTVIWDNETPICDRIPCGLPPTITNGDFISTNR 182
Query: 2510 NEFTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGKPPTC-KPVAC-- 2558
F S V Y C+ G F+L E S T+ + G+WS G P C P C
Sbjct: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS--GPAPQCIIPNKCTP 240
Query: 2559 PSIEAQLSEHVIWRLVSG--SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERP 2616
P++E + LVS SL V C PG+ ++G R ++CQA W E P
Sbjct: 241 PNVENGI-------LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE--PELP 291
Query: 2617 SCRVISCGSLSFPPNGNKIGTLTVY-------GATAIFTCNTGYTLVGSHVRECLANGLW 2669
SC + PP T G ++C GY L G+ C G W
Sbjct: 292 -----SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW 346
Query: 2670 SGSETRCLAGHCGS-PDPIVNGHISGD-GFSYRDTVVYQCNPGFRLVGTSVRICL---QD 2724
S + C C ++NG + V + C+ GF+L G+S C+ +
Sbjct: 347 SPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 406
Query: 2725 HKWSGQTPVCVPITCGHPGNPAHGFTNGSE---FNLNDVVNFTCN------TGYLLQGVS 2775
W+ PVC I C P +G G F VN+TC+ T + L G S
Sbjct: 407 SLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 466
Query: 2776 RAQCRS----NGQWSSPLPTCRVV-NCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKK 2830
+C S NG WSSP P C ++ +C P A Q N F G S+ Y C+
Sbjct: 467 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRP 525
Query: 2831 GFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANA---VLTGELFTYGAVVHYSCR 2887
+Y S +TC+ N +W C SC P P N V+T G+ ++YSC
Sbjct: 526 EYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD--IQVGSRINYSCT 582
Query: 2888 GSESLIGNDTRVC---QEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLG---DDFKTKS 2941
LIG+ + C +HWS P C CG P T A+G + ++F S
Sbjct: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIP---CGLPPTIANGDFISTNRENFHYGS 639
Query: 2942 LLRFSCEMG------HQLRGSPERTCLLN----GSWSGLQPVCEAVSCGNPGTPTNGMIV 2991
++ + C G +L G P C N G WSG P C + P NG++V
Sbjct: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILV 699
Query: 2992 SSDGILFSSS--VIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTL-ANGI 3048
S + LFS + V + C G+ G C A W P C+ + P L A
Sbjct: 700 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERT 759
Query: 3049 QFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQ-PPPVQN 3106
Q D F+ + V Y C PGY + +A++RCT G W+P+ P C+ C + N
Sbjct: 760 QRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLN 817
Query: 3107 GTV-EGSDFRWGSSISYSCMDGYQLSHSAILSCEGRG---VWKGEIPQCLPVFCGDPGIP 3162
G V + + G+ + + C +G+QL S+ C G +W +P C +FC P +
Sbjct: 818 GRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVI 877
Query: 3163 AEGRLSGKS---FTYKSEVFFQCK------SPFILVGSSRRVC----QADGTWSGIQPTC 3209
GR +GK F + V + C + F L+G S C Q +G WS P C
Sbjct: 878 PNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Query: 3210 IDPAHNTCPDPGTPHF-----GIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTW 3264
H PD HF Q ++ + +G+++ + CR Y+ + + TCL NL W
Sbjct: 938 GILGHCQAPD----HFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVW 992
Query: 3265 SGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKAD--M 3322
S + C +C+ P P + V I G + Y+C G L G S +
Sbjct: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAA 1052
Query: 3323 KWTGKSPVCK 3332
W+ K P+C+
Sbjct: 1053 HWSTKPPICQ 1062
Score = 317 bits (811), Expect = 2e-85
Identities = 263/902 (29%), Positives = 389/902 (43%), Gaps = 107/902 (11%)
Query: 2511 EFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEH 2568
EF + + + YEC G+ S + + +C ++ +W+ G C+ +C P H
Sbjct: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWT--GAKDRCRRKSCRNPPDPVNGMVH 116
Query: 2569 VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD-ERPSCRVISCGSLS 2627
VI + ++G+Q+ SC+ GY L G C +G I D E P C I CG
Sbjct: 117 VIKGI------QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPP 170
Query: 2628 FPPNGNKIGTLTV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSET 2674
NG+ I T YG+ + CN G + LVG C +N G+WSG
Sbjct: 171 TITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 230
Query: 2675 RCLAGHCGSPDPIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
+C+ + +P + NG + D FS + V ++C PGF + G C +KW +
Sbjct: 231 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL 290
Query: 2732 PVCVPITCGHPGNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSP 2788
P C + C P + H + F+ V ++C GY L+G + +C G WS
Sbjct: 291 PSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPA 349
Query: 2789 LPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-- 2846
PTC V +C D + +G+ FP + + G + + C +GF L GSSA C+ G
Sbjct: 350 APTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 406
Query: 2847 -LWDRSLPKCLAISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGND 2896
LW+ S+P C I C P V N TG E+F +G V+Y+C RG+ LIG
Sbjct: 407 SLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 466
Query: 2897 TRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRF 2945
T C D WS P C G G P H DF + L++
Sbjct: 467 TIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 2946 SCEMGHQLRGSP-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
C + G P TCL N WS + VC+ SC P P NGM+ I S + Y
Sbjct: 522 ECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
Query: 3005 ACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNK 3058
+C G++ G + C +G W+ P C I CG P T+ANG T +F +
Sbjct: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGS 639
Query: 3059 TVSYQCNPG----YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVE 3110
V+Y+CNPG V E V +I CT + G W+ P C PP V+NG +
Sbjct: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILV 699
Query: 3111 GSD---FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGR 3166
+ F + + C G+ + + C+ W+ E+P C V P + AE
Sbjct: 700 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERT 759
Query: 3167 LSGK-SFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD-PGTPH 3224
K +F+ EVF+ C+ + L G++ C G WS PTC +C D G
Sbjct: 760 QRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC---EVKSCDDFMGQLL 816
Query: 3225 FGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC-LANL--TWSGIQTECIPHACRQPET 3281
G ++G+ V F C +G+ ++GS+ C LA + W+ C C P
Sbjct: 817 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPV 876
Query: 3282 PAHA--DVRAIDLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSP 3329
+ + +++ FG T+ YTC P F L G S R C +D + W+ +P
Sbjct: 877 IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIR-CTSDPQGNGVWSSPAP 935
Query: 3330 VC 3331
C
Sbjct: 936 RC 937
Score = 312 bits (799), Expect = 4e-84
Identities = 308/1190 (25%), Positives = 466/1190 (39%), Gaps = 154/1190 (12%)
Query: 2258 KCQPPPAVPQAEM--LTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
+C P +P A LT++ +F IG ++ Y+C PGY+ I+ K S + G+
Sbjct: 42 QCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPFSIICLKNS---VWTGAKDR 98
Query: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV--DTFQSEKQF 2373
C + N + V + G +C+ ++ + + T + DT + +
Sbjct: 99 CRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNF------TSRSN---------------QLYLR 2412
+ G P + T + NF T R N +Y
Sbjct: 159 PICDRI--PCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCT 216
Query: 2413 WSTDHATSKKGFKIRYAAPYCSL----THPLKNGGIL---NRTAGAVGSKVHYFCKPGYR 2465
+ D G AP C + T P GIL NR+ ++ V + C+PG+
Sbjct: 217 SNDDQVGIWSG-----PAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 271
Query: 2466 MVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVVYEC 2522
M G C+ + +W+ P C V C P + T + F+ +V Y C
Sbjct: 272 MKGPRRVKCQ----ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSC 326
Query: 2523 HEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYG 2582
G+ L + A+ C G WS PTC+ +C QL + V+ L G
Sbjct: 327 EPGYDLRGA--ASMRCTPQGDWSPAA--PTCEVKSCDDFMGQLLNGRVLFPVNLQL---G 379
Query: 2583 AQVLLSCSPGYYLEGWRLLRCQANG---TWNIGDERPSCRVISCGSLSFPPNGNKIG--- 2636
A+V C G+ L+G C G WN P C I C S PNG G
Sbjct: 380 AKVDFVCDEGFQLKGSSASYCVLAGMESLWN--SSVPVCEQIFCPSPPVIPNGRHTGKPL 437
Query: 2637 TLTVYGATAIFTCN------TGYTLVGSHVRECLA----NGLWSGSETRC-LAGHCGSPD 2685
+ +G T +TC+ T + L+G C + NG+WS RC + GHC +PD
Sbjct: 438 EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 497
Query: 2686 PIVNGHI----SGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGH 2741
+ + + F ++ Y+C P + S+ CL + WS VC +C
Sbjct: 498 HFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKDVCKRKSCKT 556
Query: 2742 PGNPAHGFTNG-SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNG---QWSSPLPTCRVVNC 2797
P +P +G + ++ + +N++C TG+ L G S A+C +G WS+ P C+ + C
Sbjct: 557 PPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPC 616
Query: 2798 SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKG------FYLLGSSALTCMAN----GL 2847
P + N E+F YG + Y C G F L+G ++ C +N G+
Sbjct: 617 GLPPTIANGDFISTNR--ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGI 674
Query: 2848 WDRSLPKCLAISCGHPGVPANAVLTGE---LFTYGAVVHYSCRGSESLIGNDTRVCQEDS 2904
W P+C+ + P N +L + LF+ VV + C+ + G CQ +
Sbjct: 675 WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN 734
Query: 2905 HWSGALPHCTGNNPGFCGDPGTPAHGSRL---GDDFKTKSLLRFSCEMGHQLRGSPERTC 2961
W LP C+ C P H R D+F + +SCE G+ LRG+ C
Sbjct: 735 KWEPELPSCS----RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 790
Query: 2962 LLNGSWSGLQPVCEAVSCGN-PGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHC 3020
G WS P CE SC + G NG ++ + + V + C EG++ G +C
Sbjct: 791 TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC 850
Query: 3021 TANG---TWTGTAPDCTIISCGDPGTLANGIQFGTD---FTFNKTVSYQCNP----GYVM 3070
G W + P C I C P + NG G F F KTV+Y C+P G
Sbjct: 851 VLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSF 910
Query: 3071 EAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPP-----PVQNGTVEGSDFRWGSSIS 3121
+ + +TIRCT D G W+ P C + Q P SDF G+S+
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 970
Query: 3122 YSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSG-KSFTYKSEVFF 3180
Y C Y ++C VW C C P P G + S + +
Sbjct: 971 YECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 1029
Query: 3181 QCKSPFILVGSSRRVCQADGT---WSGIQPTCIDPAHNTCPDPGTPHFG--IQNSSRGYE 3235
C + L+G S C G WS P C C P T G I + +
Sbjct: 1030 SCTTGHRLIGHSSAECILSGNAAHWSTKPPIC---QRIPCGLPPTIANGDFISTNRENFH 1086
Query: 3236 VGSTVFFRC------RKGYHIQGSTTRTCLAN----LTWSGIQTEC-IPHACRQPETP-- 3282
GS V +RC RK + + G + C +N WSG +C IP+ C P
Sbjct: 1087 YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENG 1146
Query: 3283 -AHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
+D R+ L + + + C PGF + G + C+A KW + P C
Sbjct: 1147 ILVSDNRS--LFSLNEVVEFRCQPGFVMKGPRRVK-CQALNKWEPELPSC 1193
Score = 301 bits (770), Expect = 1e-80
Identities = 271/971 (27%), Positives = 380/971 (39%), Gaps = 157/971 (16%)
Query: 2441 NGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPE 2500
NG + T VGS+++Y C G+R++GHS+A C + W + P+CQ + CG+P
Sbjct: 1462 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSG-NTAHWSTKPPICQRIPCGLPP 1520
Query: 2501 SPGNGSFTGNE---FTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGK 2549
+ NG F F S V Y C+ G F+L E S T+ + G+WS G
Sbjct: 1521 TIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWS--GP 1578
Query: 2550 PPTCK-PVAC--PSIEA-----------QLSEHVIWRLVSG------------SLNEY-- 2581
P C P C P++E L+E V +R G +LN++
Sbjct: 1579 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1638
Query: 2582 ------------------------------GAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
G +V SC PGY L G L C G W+
Sbjct: 1639 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS- 1697
Query: 2612 GDERPSCRVISCGS-LSFPPNGNKIGTLTVY-GATAIFTCNTGYTLVGSHVRECLANG-- 2667
E P C V SC L P+G + L + GA F C+ G+ L GS V C+ G
Sbjct: 1698 -PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR 1756
Query: 2668 -LWSGSETRCLAGHCGSPDPIVNGHISGD---GFSYRDTVVYQCNPG------FRLVGTS 2717
LW+ S C C +P I+NG +G Y + Y C+P F L+G S
Sbjct: 1757 SLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES 1816
Query: 2718 VRICLQDHK----WSGQTPVC-VPITCGHPGNPAH-GFT------NGSEFNLNDVVNFTC 2765
C D WS P C + + GH P F N EF + +N+ C
Sbjct: 1817 TIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYEC 1876
Query: 2766 NTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSIL 2825
GY + S C N WSS CR +C P N + H ++G ++
Sbjct: 1877 RPGYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVH----INTDTQFGSTVN 1931
Query: 2826 YHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVPANAVLTGE---LFTYG 2879
Y C +GF L+GS + TC+ +G WD+ P C ISC P +N F G
Sbjct: 1932 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1991
Query: 2880 AVVHYSCRGSES------LIGNDTRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAH 2929
VV Y C L+G + C WS P C N +
Sbjct: 1992 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIR 2051
Query: 2930 GSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM 2989
F ++RF C+ G + GS C NG W P C V C P +G
Sbjct: 2052 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGE 2110
Query: 2990 IVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGD-PGTLAN 3046
S FS V Y+C Y G + HCT G W+ AP CT+ SC D G L +
Sbjct: 2111 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 2170
Query: 3047 G-IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR---WNPSKPVCKAVLCPQPP 3102
G + + VS+ C+ G+ ++ +++ C G WN S PVC+ + CP PP
Sbjct: 2171 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSAS--HCVLAGMKALWNSSVPVCEQIFCPNPP 2228
Query: 3103 PVQNGTVEGS---DFRWGSSISYSCMDG------YQLSHSAILSC----EGRGVWKGEIP 3149
+ NG G+ D +G ISY+C + L + + C +G GVW P
Sbjct: 2229 AILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAP 2288
Query: 3150 QC---LPVFCGDPGIPAEGRLSG---KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3203
+C +P C P G G + + + C ++LVG C G WS
Sbjct: 2289 RCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWS 2348
Query: 3204 GIQPTCIDPAHNTCPDPGTPHFGIQNS---SRGYEVGSTVFFRCRKGYHIQGSTTRTCLA 3260
+ C + C P + GI + Y G V +C GY ++GS C A
Sbjct: 2349 QLDHYCKEV---NCSFPLFMN-GISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQA 2404
Query: 3261 NLTWSGIQTEC 3271
+ W +C
Sbjct: 2405 DDRWDPPLAKC 2415
Score = 282 bits (722), Expect = 4e-75
Identities = 302/1191 (25%), Positives = 461/1191 (38%), Gaps = 156/1191 (13%)
Query: 2259 CQPPPAVPQAEML-TEDDDFEIGDFVKYQCHPG------YTLVGTDILTCKLSSQLQ--F 2309
C PP + + + T ++F G V Y+C+PG + LVG + C + +
Sbjct: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
Query: 2310 EGSLPTC--EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTF 2367
G P C +C V +G+++S N + +P FV
Sbjct: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVV---EFRCQPG-----FVMKG 274
Query: 2368 QSEKQFDALEVFDG-----SSGQSPLLVVLSGNHTEQS--NFTSRSNQLY-------LRW 2413
+ AL ++ S P VL T++ NF+ Y LR
Sbjct: 275 PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 334
Query: 2414 STDHATSKKGFKIRYAAPYCSLTH------PLKNGGILNRTAGAVGSKVHYFCKPGYRMV 2467
+ + +G AAP C + L NG +L +G+KV + C G+++
Sbjct: 335 AASMRCTPQG-DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLK 393
Query: 2468 GHSNATCRRNPLGMYQ-WDSLTPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVVYECH 2523
G S + C GM W+S P+C+ + C P NG TG F V Y C
Sbjct: 394 GSSASYCVL--AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCD 451
Query: 2524 ------EGFKL--ESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVS 2575
F L ES+ + T+ Q +G+WS+ P C + Q +H ++ +
Sbjct: 452 PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPA--PRCGILG----HCQAPDHFLFAKLK 505
Query: 2576 GSLN----EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPN 2631
N G + C P YY + + C N W+ + C+ SC + P N
Sbjct: 506 TQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWS--SPKDVCKRKSCKTPPDPVN 562
Query: 2632 GN-KIGTLTVYGATAIFTCNTGYTLVGSHVRECLANG---LWSGSETRCLAGHCGSPDPI 2687
G + T G+ ++C TG+ L+G EC+ +G WS C CG P I
Sbjct: 563 GMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTI 622
Query: 2688 VNGHI---SGDGFSYRDTVVYQCNPG------FRLVGTSVRICLQDHK----WSGQTPVC 2734
NG + + F Y V Y+CNPG F LVG C + WSG P C
Sbjct: 623 ANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Query: 2735 VPITCGHPGNPAHGF---TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT 2791
+ P N +G N S F+LN+VV F C G++++G R +C++ +W LP+
Sbjct: 683 IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPS 742
Query: 2792 CRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRS 2851
C V C P V +A R Q ++F G + Y C+ G+ L G++++ C G W +
Sbjct: 743 CSRV-CQPPPDVLHAER--TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPA 799
Query: 2852 LPKCLAISC-GHPGVPANA-VLTGELFTYGAVVHYSCRGSESLIGNDTRVC---QEDSHW 2906
P C SC G N VL GA V + C L G+ C +S W
Sbjct: 800 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLW 859
Query: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLG---DDFKTKSLLRFSCE------MGHQLRGSP 2957
+ ++P C FC P +G G + F + ++C+ L G
Sbjct: 860 NSSVPVC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 916
Query: 2958 ERTCLL----NGSWSGLQPVCEAVSCGNPGTPTNGMI------VSSDGILFSSSVIYACW 3007
C NG WS P C + G+ P + + ++ +S+ Y C
Sbjct: 917 TIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 974
Query: 3008 EGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANG-IQFGTDFTFNKTVSYQCNP 3066
Y C N W+ C SC P NG + TD ++Y C
Sbjct: 975 PEYYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTT 1033
Query: 3067 GYVMEAVTSATIRCTKDG---RWNPSKPVCKAVLCPQPPPVQNG---TVEGSDFRWGSSI 3120
G+ + +SA C G W+ P+C+ + C PP + NG + +F +GS +
Sbjct: 1034 GHRLIGHSSA--ECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 1091
Query: 3121 SYSCMDG------YQLSHSAILSCEGR----GVWKGEIPQC-LPVFCGDPGIPAEGRLSG 3169
+Y C G ++L + C G+W G PQC +P C P + +S
Sbjct: 1092 TYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSD 1151
Query: 3170 KS--FTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC-PDPGTPHF- 3225
F+ V F+C+ F++ G R CQA W P+C C P P H
Sbjct: 1152 NRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAE 1207
Query: 3226 GIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR--QPETPA 3283
Q + G VF+ C GY ++G+ + C WS C +C +
Sbjct: 1208 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLN 1267
Query: 3284 HADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMK--WTGKSPVCK 3332
+ ++L G + + C GF L G S A M+ W PVC+
Sbjct: 1268 GRVLFPVNL-QLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 1317
Score = 275 bits (703), Expect = 6e-73
Identities = 259/974 (26%), Positives = 392/974 (40%), Gaps = 121/974 (12%)
Query: 2452 VGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGS---FT 2508
+G+ ++Y C+PGY S C +N + W C+ SC P P NG
Sbjct: 65 IGTYLNYECRPGYSGRPFS-IICLKNSV----WTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
Query: 2509 GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG-LWSNKGKPPTCKPVACPSIEAQLSE 2567
G +F S++ Y C +G++L S AT + D +W N + P C + C +
Sbjct: 120 GIQF--GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDN--ETPICDRIPCGLPPTITNG 175
Query: 2568 HVIWRLVSGSLNEYGAQVLLSCSPG------YYLEGWRLLRCQAN----GTWNIGDERPS 2617
I + YG+ V C+PG + L G + C +N G W+ P
Sbjct: 176 DFI--STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS--GPAPQ 231
Query: 2618 CRVISCGSLSFPPNGNKIG---TLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSET 2674
C + + + NG + +L F C G+ + G +C A W
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 291
Query: 2675 RCLAGHCGSPDPIVNGHIS---GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
C + C P +++ + D FS V Y C PG+ L G + C WS
Sbjct: 292 SC-SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAA 350
Query: 2732 PVCVPITC-GHPGNPAHG-FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ---WS 2786
P C +C G +G L V+F C+ G+ L+G S + C G W+
Sbjct: 351 PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWN 410
Query: 2787 SPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCK------KGFYLLGSSAL 2840
S +P C + C P + N G+ E F +G ++ Y C F L+G S +
Sbjct: 411 SSVPVCEQIFCPSPPVIPNGRHTGKP--LEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
Query: 2841 TC----MANGLWDRSLPKCLAISCGHPGVPANAVL-------TGELFTYGAVVHYSCRGS 2889
C NG+W P+C + GH P + + F G + Y CR
Sbjct: 469 RCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR-- 524
Query: 2890 ESLIGNDTRV-CQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS-RLGDDFKTKSLLRFSC 2947
G + C ++ WS C + C P P +G + D + S + +SC
Sbjct: 525 PEYYGRPFSITCLDNLVWSSPKDVCKRKS---CKTPPDPVNGMVHVITDIQVGSRINYSC 581
Query: 2948 EMGHQLRGSPERTCLLNGS---WSGLQPVCEAVSCGNPGTPTNGMIVSS--DGILFSSSV 3002
GH+L G C+L+G+ WS P+C+ + CG P T NG +S+ + + S V
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 641
Query: 3003 IYACWEG------YKTSGLMTRHCTAN----GTWTGTAPDCTIISCGDPGTLANGIQFGT 3052
Y C G ++ G + +CT+N G W+G AP C I + P + NGI
Sbjct: 642 TYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSD 701
Query: 3053 D---FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPV---QN 3106
+ F+ N+ V ++C PG+VM+ ++C +W P P C V C PP V +
Sbjct: 702 NRSLFSLNEVVEFRCQPGFVMKG--PRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAER 758
Query: 3107 GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGD-PGIPAEG 3165
+ +F G + YSC GY L +A + C +G W P C C D G G
Sbjct: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
Query: 3166 R-LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADG---TWSGIQPTCIDPAHNTCPDPG 3221
R L + ++V F C F L GSS C G W+ P C CP P
Sbjct: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC---EQIFCPSPP 875
Query: 3222 TPHFGIQNSSRGYEV---GSTVFFRC------RKGYHIQGSTTRTCLA----NLTWSGIQ 3268
G +++ + EV G TV + C + + G +T C + N WS
Sbjct: 876 VIPNG-RHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPA 934
Query: 3269 TEC-IPHACRQPETPAHADVR----AIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMK 3323
C I C+ P+ A ++ A D P G +L Y C P ++ G TC ++
Sbjct: 935 PRCGILGHCQAPDHFLFAKLKTQTNASDFP-IGTSLKYECRPEYY--GRPFSITCLDNLV 991
Query: 3324 WTGKSPVCKSKGVR 3337
W+ VCK K +
Sbjct: 992 WSSPKDVCKRKSCK 1005
Score = 186 bits (473), Expect = 3e-46
Identities = 578/2656 (21%), Positives = 898/2656 (33%), Gaps = 601/2656 (22%)
Query: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
KNSV + C +P P NG + G+ +++SC Y L GS S TC
Sbjct: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII 147
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVIT-TTDPDKVI 451
+T+ W + PIC CG +G S N +N H V+T +P
Sbjct: 148 SGDTVI-WDNETPICDRIPCGLPPTITNGDFISTN-----RENFHYGSVVTYRCNPGSGG 201
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
+ FE VG+ I SN DD +
Sbjct: 202 RKVFE-----------LVGEPS--------------------IYCTSN--------DDQV 222
Query: 512 GSPGFKAVYQEIEKGGCGDP----GIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVIT 567
G A Q I C P GI R S F + + F C F + G R +
Sbjct: 223 GIWSGPAP-QCIIPNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVK 279
Query: 568 CQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIF 627
CQ N+W P SC ++ + + N PG +
Sbjct: 280 CQALNKWEPELP----SCSRVCQPPPDVLHAERTQRDKDN---------FSPGQEVF--- 323
Query: 628 NDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFN 687
+ EP +D +R Q D S
Sbjct: 324 --YSCEPGYDLRGAAS---------------------------MRCTPQGDWSPAA---- 350
Query: 688 ITYTTFGQNECHD-PGIPINGR-RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGN 745
T C D G +NGR F LG+ V F CD+GF + +GS + C+L
Sbjct: 351 ---PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGME 406
Query: 746 VVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKP-GHSIKITFDRF 804
+W+S+VP CE + S ++P G H +E P G ++ T D
Sbjct: 407 SLWNSSVPVCE-----QIFCPSPPVIPNG--------RHTGKPLEVFPFGKTVNYTCDPH 453
Query: 805 QTE------VNYDTLEVRDGP------ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTD 852
+ T+ P +S +P G QAP + F L T+
Sbjct: 454 PDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTN 509
Query: 853 NSRSSIGFLIHYE----------SVT-------------LESDSCLDPGIPVNGHRHG-G 888
S IG + YE S+T + SC P PVNG H
Sbjct: 510 ASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT 569
Query: 889 DFGIRSTVTFSCDPGYTL---SDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLS 944
D + S + +SC G+ L S E ++ W+ P C + CG +G +S
Sbjct: 570 DIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 629
Query: 945 PGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVAR--LTG 1002
+F+ S+ T + G G + +F S + + G +S P + +
Sbjct: 630 TNRENFHYGSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 686
Query: 1003 SVLPHTIKAGLFGN-------------FTAQLRFISDFSISYEGFNITFSEYDLEPCDDP 1049
P ++ G+ + F Q F+ + + E +L C
Sbjct: 687 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
Query: 1050 GVP-------AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
P ++R +F G + +SC GY L GA + C G WS P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD--WSPAAPTCE 804
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYD 1162
+ S G LL N ++ + + G + F EG LK
Sbjct: 805 VK---SCDDFMGQLL----------NGRVLFPVNLQLGAKV-----DFVCDEGFQLK--- 843
Query: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPG 1222
G +S L + LW N++ +Q F C P
Sbjct: 844 GSSASYCVL--------------AGMESLW---NSSVPVCEQIF-----------CPSPP 875
Query: 1223 -IPNYGYRIRDEGHFT-DTVVLYSCNP------GYAMHGSNTLTCLSGDR--RVWDKPLP 1272
IPN + + F V Y+C+P + + G +T+ C S + VW P P
Sbjct: 876 VIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 935
Query: 1273 SC--IAECGGQIH---AATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE 1327
C + C H A + + +P C P L +
Sbjct: 936 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL----- 990
Query: 1328 MAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLT-LQFDSDFFIS---------- 1376
VW P D + K S P+ ++ + +T +Q S S
Sbjct: 991 -------VWSSPKD---VCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 1377 ------KSGFSIQFSTS----IAATCNDPGMPQNGTRYGDSRE---AGDTVTFQCDPG-- 1421
SG + +ST C P NG +RE G VT++C+PG
Sbjct: 1041 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 1100
Query: 1422 ----YQLQGQAKITCVQLNNRF-FWQPDPPTCIAACGGNLTGP---AGVILS-------- 1465
++L G+ I C +++ W P CI T P G+++S
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDNRSLFSL 1158
Query: 1466 ---------PNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH---IYEGED 1513
P + P +C K P+ L S +P D LH +D
Sbjct: 1159 NEVVEFRCQPGFVMKGPRRVKCQALNKWEPE----LPSCSRVCQPPPDVLHAERTQRDKD 1214
Query: 1514 SNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD-PGNIM 1572
+ SP + + + + S+ + D S + ++C D G ++
Sbjct: 1215 NFSPGQEVFYSCEPGYDLRGAA-SMRCTPQGDWSPAAPTCEV-------KSCDDFMGQLL 1266
Query: 1573 NG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN---APC-- 1626
NG + +LG+ + + CD G+++ S+ CV+ A + W+ +P C P
Sbjct: 1267 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL-AGMESLWNSSVPVCEQIFCPSPP 1325
Query: 1627 ---GGQYTGSEGVVLSPNYPHNYTA-------------GQICLYSITVPKEFVVFGQFAY 1670
G++TG V NYT G+ + + P+ V+ A
Sbjct: 1326 VIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 1385
Query: 1671 FQTALNDLAELFDGTHAQAR---LLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1727
L H QA L + L + P+ TS L++ + R F
Sbjct: 1386 RCGILG---------HCQAPDHFLFAKLKTQTNASDFPIGTS----LKYECRPEYYGRPF 1432
Query: 1728 HF-----VYQAVPR--TSDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTA 1779
+ + P+ C + P+P G + ++ GS + + C G+ L G ++
Sbjct: 1433 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSS 1492
Query: 1780 LHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEG 1838
C N A W+ P C +PC T G +S N N + +VT
Sbjct: 1493 AECILSGNT-AHWSTKPPICQRIPCGLPPTIANGDFIST-------NRENFHYGSVVTYR 1544
Query: 1839 SGI---------QIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNS--TSN 1887
+ + S N D + I G AP+ + T P + N S+
Sbjct: 1545 CNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSG---PAPQCIIPNKCTPPNVENGILVSD 1601
Query: 1888 QLYLHFQSDISVAAAGFHLEYKTVGLAACQ-----EPALPSNS--------IKIG----- 1929
L +++ K CQ EP LPS S I G
Sbjct: 1602 NRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPS 1661
Query: 1930 --DRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLSTLGGVI 1986
D + + + CEPGY L+G + + C P W+ +P C + +C L L
Sbjct: 1662 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTP--QGDWSPEAPRCAVKSCDDFLGQL---- 1715
Query: 1987 LSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFS 2046
P +P NL ++S G ++ + +H L ++ S + +
Sbjct: 1716 --PHGRVLFPLNLQLGAKVSFVCDEGFRLK----GSSVSHCVLVGMRSLWNNSVPVCE-- 1767
Query: 2047 GTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMI---NSD 2103
H + CP+PP NG + D
Sbjct: 1768 -----------------HIF---------------------CPNPPAILNGRHTGTPSGD 1789
Query: 2104 YSVGQSVSFECYP------GYILIGHPVLTC---QHGINRNWNYPFPRCD--APCGYNVT 2152
G+ +S+ C P + LIG + C HG N W+ P PRC+ G+ T
Sbjct: 1790 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHG-NGVWSSPAPRCELSVRAGHCKT 1848
Query: 2153 SQNGTIYSPGFP---DEYPILKDCIWLITVPPGH-GVYINFTLLQTEAVNDYIAVWDGPD 2208
+ SP P E+P+ + PG+ G + + L+ VW +
Sbjct: 1849 PEQFPFASPTIPINDFEFPVGTSLNY--ECRPGYFGKMFSISCLEN-------LVWSSVE 1899
Query: 2209 QN------SPQLGVFSGNTALETAYSSTNQVLLKFHSDF-------------SNGGFFVL 2249
N P F+G + T + V + F N +
Sbjct: 1900 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK 1959
Query: 2250 NFHAFQLKKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPG------YTLVGTDILTC- 2301
++ C+PPP + + + + F G V YQCH G + LVG + C
Sbjct: 1960 KAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCT 2019
Query: 2302 -KLSSQLQFEGSLPTCEA--QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNY 2358
K + P C + +C A EV I PG F + T + +P +
Sbjct: 2020 SKDDQVGVWSSPPPRCISTNKCTAPEV----ENAIRVPG--NRSFFTLTEIIRFRCQPGF 2073
Query: 2359 NITIFVDTFQSEKQFD-ALEVFDGSSGQSPLLVVLSGNHT--EQSNFTSRSNQLY----- 2410
+ + T Q + ++ S P +L G HT Q NF+ Y
Sbjct: 2074 -VMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPS 2132
Query: 2411 --LRWSTD-HATSKKGFKIRYAAPYCSLTH------PLKNGGILNRTAGAVGSKVHYFCK 2461
LR + H T + + AP C++ L +G +L +G+KV + C
Sbjct: 2133 YDLRGAASLHCTPQGDWSPE--APRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCD 2190
Query: 2462 PGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEF---TLDSKV 2518
G+R+ G S + C + W+S P+C+ + C P + NG TG F ++
Sbjct: 2191 EGFRLKGRSASHCVLAGMKAL-WNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEI 2249
Query: 2519 VYECHE------GFKL--ESSQQATAVCQEDGLWSNKGKPPTCK---PVACPSIEAQLSE 2567
Y C F L ESS + T+ Q +G+WS+ P C+ P ACP +
Sbjct: 2250 SYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPA--PRCELSVPAACPHPPKIQNG 2307
Query: 2568 HVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLS 2627
H I V SL G + C PGY L G + C G W+ D C+ ++C S
Sbjct: 2308 HYIGGHV--SLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDH--YCKEVNC---S 2360
Query: 2628 FPPNGNKIG------TLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHC 2681
FP N I + YG C GYTL GS +C A+ W +C +
Sbjct: 2361 FPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS--- 2417
Query: 2682 GSPDPIVNGHISGDGF 2697
+ D ++ G +SG F
Sbjct: 2418 RTHDALIVGTLSGTIF 2433
Score = 61.2 bits (147), Expect = 2e-08
Identities = 109/468 (23%), Positives = 165/468 (35%), Gaps = 107/468 (22%)
Query: 144 TCGNPGEILKGVLH-GTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+CG P E G++H T G + YSC G+ L G TC+VS GN +WD AP C
Sbjct: 1906 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVS-GNNVTWDKKAPIC 1964
Query: 203 RAEGACGGTLRGTSSSISSPHFPS----EYENNADCTWTILAEP-GDTIALVFTDFQLEE 257
+IS+ F S + N T+ P G+ + F+L
Sbjct: 1965 EIISC------EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL------FELVG 2012
Query: 258 GYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
S + +W + P P S N ++ R G + F + + I
Sbjct: 2013 ERSIYCTSKDDQVGVW----SSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRF 2067
Query: 318 KSR-GVKMLPSKDGSHKNSVLSQG--GVAL--VSDMCPDPGIPENGRRAGS--DFSRVGA 370
+ + G M+ GSH + G G L S +C P +G S D G
Sbjct: 2068 RCQPGFVMV----GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQ 2123
Query: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNL-RGPSGVITSPNYP 429
V +SCE +Y L+G+ S+ C + WS P C ++C L + P G + P
Sbjct: 2124 EVFYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP--- 2176
Query: 430 VQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSS 489
L+ G V D G + L G S
Sbjct: 2177 ----------------------------LNLQLGAKVSFVCDEG---------FRLKGRS 2199
Query: 490 VPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSF---LH 546
+++ +W + P + ++ C +P G+ TG+ F +
Sbjct: 2200 ASHCVLAGMKALW-------NSSVPVCEQIF-------CPNPPAILNGRHTGTPFGDIPY 2245
Query: 547 GDTLTFECPA------AFELVGERVITC----QQNNQWSGNKPSCVFS 584
G +++ C F L+GE I C Q N WS P C S
Sbjct: 2246 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELS 2293
Score = 60.8 bits (146), Expect = 2e-08
Identities = 105/474 (22%), Positives = 162/474 (34%), Gaps = 113/474 (23%)
Query: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNAAHWS 605
Query: 197 FPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF---- 250
P C+ G +I++ F S N T PG VF
Sbjct: 606 TKPPICQRIPC------GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 659
Query: 251 -TDFQLEEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKG 304
D + I AP + T N+ + ++ S N R + G
Sbjct: 660 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 719
Query: 305 FNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSD 364
F + + + ++ LPS + V PD E +R +
Sbjct: 720 FVMKGPRRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDN 765
Query: 365 FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPS 420
FS G V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 766 FS-PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG-- 818
Query: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
+PV + A +F + G+
Sbjct: 819 ----RVLFPVNLQLGAKV------------------DFVCDEGFQ--------------- 841
Query: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
L GSS +++ +W + P + ++ C P + G+ T
Sbjct: 842 ----LKGSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHT 883
Query: 541 GSS---FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
G F G T+ + C +F+L+GE I C Q N WS P C
Sbjct: 884 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 58.9 bits (141), Expect = 9e-08
Identities = 104/468 (22%), Positives = 160/468 (34%), Gaps = 113/468 (24%)
Query: 144 TCGNPGEILKGVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+C NP + + G++H + G +I+YSC GY L G + TCI+S G+ WD P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS-GDTVIWDNETPIC 161
Query: 203 RAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF-----TDFQL 255
G +I++ F S N T PG VF
Sbjct: 162 DRIPC------GLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 215
Query: 256 EEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKGFNAQFQ 310
D + I AP + T N+ + ++ S N R + GF +
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 311 VKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGA 370
+ + ++ LPS + V PD E +R +FS G
Sbjct: 276 RRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDNFS-PGQ 320
Query: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPSGVITSP 426
V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 321 EVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG------RV 370
Query: 427 NYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLT 486
+PV + A +F + G+ L
Sbjct: 371 LFPVNLQLGAKV------------------DFVCDEGFQ-------------------LK 393
Query: 487 GSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSS--- 543
GSS +++ +W + P + ++ C P + G+ TG
Sbjct: 394 GSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHTGKPLEV 439
Query: 544 FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
F G T+ + C +F+L+GE I C Q N WS P C
Sbjct: 440 FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 58.9 bits (141), Expect = 9e-08
Identities = 104/474 (21%), Positives = 161/474 (33%), Gaps = 113/474 (23%)
Query: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNAAHWS 1055
Query: 197 FPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF---- 250
P C+ G +I++ F S N T PG VF
Sbjct: 1056 TKPPICQRIPC------GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 1109
Query: 251 -TDFQLEEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKG 304
D + I AP + T N+ + ++ S N R + G
Sbjct: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 1169
Query: 305 FNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSD 364
F + + + ++ LPS + V PD E +R +
Sbjct: 1170 FVMKGPRRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDN 1215
Query: 365 FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPS 420
FS G V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 1216 FS-PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG-- 1268
Query: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
+PV + A +F + G+
Sbjct: 1269 ----RVLFPVNLQLGAKV------------------DFVCDEGFQ--------------- 1291
Query: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
L GSS +++ +W + P + ++ C P + G+ T
Sbjct: 1292 ----LKGSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHT 1333
Query: 541 GSS---FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
G F G + + C +F+L+GE I C Q N WS P C
Sbjct: 1334 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 1387
Score = 47.8 bits (112), Expect = 2e-04
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 1447 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNTAHWS 1505
Query: 197 FPAPFCR 203
P C+
Sbjct: 1506 TKPPICQ 1512
Score = 39.3 bits (90), Expect = 0.070
Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 142 SHTCGNPGEILKGV---LHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
S C P EIL G H F+ G ++ YSC PGY L G A L C W
Sbjct: 1644 SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ----GDWSPE 1699
Query: 199 APFC 202
AP C
Sbjct: 1700 APRC 1703
Score = 38.1 bits (87), Expect = 0.16
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 142 SHTCGNPGEILKG---VLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
S C P EIL G + H F+ G ++ YSC P Y L G A L C W
Sbjct: 2097 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQ----GDWSPE 2152
Query: 199 APFC 202
AP C
Sbjct: 2153 APRC 2156
Score = 35.8 bits (81), Expect = 0.78
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 389 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 439
Query: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 440 --FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 493
Score = 35.8 bits (81), Expect = 0.78
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 839 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 889
Query: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 890 --FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 943
Score = 35.8 bits (81), Expect = 0.78
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 1289 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 1339
Query: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 1340 --FPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 1393
Score = 33.5 bits (75), Expect = 3.9
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 15/71 (21%)
Query: 142 SHTCGNPGEILKGVLHGTR-------FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGAS 194
S C P + VLH R F+ G ++ YSC PGY L G A + C
Sbjct: 294 SRVCQPPPD----VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ----GD 345
Query: 195 WDFPAPFCRAE 205
W AP C +
Sbjct: 346 WSPAAPTCEVK 356
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 320 bits (820), Expect = 2e-86
Identities = 269/982 (27%), Positives = 404/982 (41%), Gaps = 103/982 (10%)
Query: 2433 CSLTHPLKNGGI-LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLC 2491
C P+ NG I T AVG+ + Y C +R++G + C WD P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2492 QAV----SCGIPESPGNGSFTGNE-FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSN 2546
+ SC P PG G+ + V + C F + ++ CQ + +W
Sbjct: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGP 140
Query: 2547 KGKPPTCK---PVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRC 2603
+ PTC P+ CP++ + H V GS+ G V SC GY L G +++ C
Sbjct: 141 T-RLPTCVSVFPLECPALPMIHNGHHTSENV-GSIAP-GLSVTYSCESGYLLVGEKIINC 197
Query: 2604 QANGTWNIGDERPSCRVISCGSLSFPPNGN-KIGTLTVYGATAIFTCNTGYTLVGSHVRE 2662
++G W+ P+C C SL PNG K + G TA F C+ GY L G
Sbjct: 198 LSSGKWSAVP--PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 2663 CLANG---LWSGSETRCLAGHCGSPDPIVNGHISGDGF---SYRDTVVYQCNP------G 2710
C+ G W+ C C SP PI+NG G+ SY V Y C+P
Sbjct: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2711 FRLVGTSVRICLQDHK----WSGQTPVCV----PITCGHPGNPAHGFTNGSE--FNLNDV 2760
F L+G S C D + WSG P C + C HP +G + + ND
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
Query: 2761 VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEY 2820
V F C G+ L+G + +C + G W P C C P + N + + F+
Sbjct: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMV--RFDP 431
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGA 2880
G SI Y C G+ L+G ++ C + G+W +P+C +C G +LT +
Sbjct: 432 GTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLLTKPQHQFVR 488
Query: 2881 V-VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLG---DD 2936
V+ SC L G+ + CQ W + C C P +G+ G +D
Sbjct: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTGSSLED 545
Query: 2937 FKTKSLLRFSCEMGHQ------LRGSPERTCLLN----GSWSGLQPVCE----AVSCGNP 2982
F + + ++C G + L G C N G+WSG P+C+ AV C +
Sbjct: 546 FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
Query: 2983 GTPTNGMIVSSDGILF-SSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDP 3041
I + F + +V + C+ G+ G C A+ TW P C +C
Sbjct: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHV 665
Query: 3042 GTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQP 3101
+ G+ + V+ C GY + + ++G W P+CK + C P
Sbjct: 666 RQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPP 722
Query: 3102 PPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSC----EGRGVWKGEIPQCL-- 3152
P + NG G +F +G+ +SY C G+ L L C +G G W G PQCL
Sbjct: 723 PVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRS 782
Query: 3153 -PVF-CGDPGIPAEGRLSG--KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPT 3208
PV C +P + +L+ ++++ V+ C FI+ GS C D TW PT
Sbjct: 783 PPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPT 842
Query: 3209 CIDPAHNTCPDPG-TP---HFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTW 3264
CI A CP P TP H G N +R + G ++ + C +GY + G C TW
Sbjct: 843 CIKKAFIGCPPPPKTPNGNHTG-GNIAR-FSPGMSILYSCDQGYLLVGEALLLCTHEGTW 900
Query: 3265 SGIQTECIPHACRQPETPAHADVRAID-------LPTFGYTLVYTCHPGFFLAGGSEHRT 3317
S + PH C++ + AD+ I + +G + C G+ L GS
Sbjct: 901 S----QPAPH-CKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE-GSPQSQ 954
Query: 3318 CKADMKWTGKSPVCKSKGVREV 3339
C++D +W VC+S+ + V
Sbjct: 955 CQSDHQWNPPLAVCRSRSLAPV 976
Score = 278 bits (711), Expect = 7e-74
Identities = 248/927 (26%), Positives = 356/927 (38%), Gaps = 113/927 (12%)
Query: 2416 DHATSKKGFKIRYAAPYCSLTHPLKNGG--ILNRTAGAVGSKVHYFCKPGYRMVGHSNAT 2473
D K K Y Y S P+ GG I T G V + CK + M G+ +
Sbjct: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW 131
Query: 2474 CRRNPLGMYQWD-SLTPLCQAV---SCGIPESPGNGSFTGNE---FTLDSKVVYECHEGF 2526
C+ N + W + P C +V C NG T V Y C G+
Sbjct: 132 CQANNM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 2527 KLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE-----Y 2581
L + C G WS PPTC+ C S+ R +G + E
Sbjct: 188 LLVGEKIIN--CLSSGKWS--AVPPTCEEARCKSLG---------RFPNGKVKEPPILRV 234
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV- 2640
G C GY L+G RC G + P C I C S NG IG
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 2641 --YGATAIFTCN------TGYTLVGSHVRECLAN----GLWSGSETRC----LAGHCGSP 2684
YG+ +TC+ + L+G C + G WSG RC A C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 2685 DPIVNGHISG--DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
+ +SG D ++Y DTV++ C GF L G+ C W PVC C P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP 413
Query: 2743 GNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
N +G F+ + ++CN GY+L G QC S G W+ P+P C+V C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEA 473
Query: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAIS 2859
G + Q F + C +G+ L GS C W + C I+
Sbjct: 474 TG--RQLLTKPQHQFVRP-----DVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 2860 CGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGNDTRVC----QEDSHW 2906
C P V N TG E F YG V Y+C RG E SLIG T C QE W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLGD---DFKTKSLLRFSCEMGHQLRGSPERTCLL 2963
SG P C + A+G ++ + + F C G L+GS + C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHC--T 3021
+ +W PVCE +C + + S L ++S C +GY+ +G + C
Sbjct: 647 DNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS----CQDGYQLTGHAYQMCQDA 702
Query: 3022 ANGTWTGTAPDCTIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPGYVMEAVTSATI 3078
NG W P C +I C P + NG G +F + VSY+C+ G+ + + +
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYL--LGEKKL 760
Query: 3079 RCTKD----GRWNPSKPVC----KAVLCPQPPPVQNG---TVEGSDFRWGSSISYSCMDG 3127
+C D G W+ P C CP P V++G S + + C G
Sbjct: 761 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPG 819
Query: 3128 YQLSHSAILSCEGRGVWKGEIPQCLP---VFCGDPGIPAEGRLSGKS---FTYKSEVFFQ 3181
+ ++ S ++ C W +P C+ + C P G +G + F+ + +
Sbjct: 820 FIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYS 879
Query: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNS---SRGYEVGS 3238
C ++LVG + +C +GTWS P C + C P GIQ + Y+ G+
Sbjct: 880 CDQGYLLVGEALLLCTHEGTWSQPAPHCKEV---NCSSPADMD-GIQKGLEPRKMYQYGA 935
Query: 3239 TVFFRCRKGYHIQGSTTRTCLANLTWS 3265
V C GY ++GS C ++ W+
Sbjct: 936 VVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 265 bits (676), Expect = 8e-70
Identities = 244/985 (24%), Positives = 392/985 (39%), Gaps = 114/985 (11%)
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQ--FEGSLPTC 2316
C PP + + +G ++Y C + L+G L C ++ ++ P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2317 E-----AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDT---FQ 2368
E + CP V G + P + +S T + N N +++ +
Sbjct: 83 EYFNKYSSCPEPIV---PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
Query: 2369 SEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKI-- 2426
+ + VF + P L ++ H N S + L + +S + G KI
Sbjct: 140 PTRLPTCVSVFPL---ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
Query: 2427 -----RYAA-------PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATC 2474
+++A C NG + VG ++FC GYR+ G ++ C
Sbjct: 197 CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
Query: 2475 RRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEF---TLDSKVVYEC----HEGFK 2527
G+ W + P+C+ + C P NG GN + S V Y C EG
Sbjct: 257 VIAGQGV-AWTKM-PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2528 L----ESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEY-- 2581
ES+ + T Q+ G WS G P C+ ++ +++ + + R+VSG + Y
Sbjct: 315 FILIGESTLRCTVDSQKTGTWS--GPAPRCE-LSTSAVQCPHPQILRGRMVSGQKDRYTY 371
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY 2641
V+ +C G+ L+G + +RC A GTW P C C + NG K V
Sbjct: 372 NDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEK-ECQAPPNILNGQKEDRHMVR 428
Query: 2642 ---GATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS 2698
G + ++CN GY LVG +C + G+W+ +C C + + ++
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQL---LTKPQHQ 485
Query: 2699 Y-RDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPG---NPAHGFTNGSE 2754
+ R V C G++L G+ + C W + +C ITC P N AH ++ +
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLED 545
Query: 2755 FNLNDVVNFTCNTG------YLLQGVSRAQCRSN----GQWSSPLPTCRV----VNCSDP 2800
F V +TCN G + L G S +C SN G WS P P C++ V CS
Sbjct: 546 FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
Query: 2801 GFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISC 2860
+ N + + P + Y ++ + C GF L GSS + C A+ WD +P C +C
Sbjct: 606 -HIANGYKISGKEAP--YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC 662
Query: 2861 GHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQ--EDSHWSGALPHCTGNNP 2918
H + G +V+ SC+ L G+ ++CQ E+ W +P C +
Sbjct: 663 QHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH- 718
Query: 2919 GFCGDPGTPAHGSRLG---DDFKTKSLLRFSCEMGHQLRGSPERTCLLN----GSWSGLQ 2971
C P +G G ++F + + + C+ G L G + C + GSWSG
Sbjct: 719 --CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 776
Query: 2972 PVC----EAVSCGNPGTPTNGMIVSSDGILFSSSVIYA-CWEGYKTSGLMTRHCTANGTW 3026
P C C NP + + + ++Y C G+ +G C + TW
Sbjct: 777 PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTW 836
Query: 3027 TGTAPDC---TIISCGDPGTLANGIQFGTD---FTFNKTVSYQCNPGYVMEAVTSATIRC 3080
P C I C P NG G + F+ ++ Y C+ GY++ V A + C
Sbjct: 837 VPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL--VGEALLLC 894
Query: 3081 TKDGRWNPSKPVCKAVLCPQPPP---VQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILS 3137
T +G W+ P CK V C P +Q G +++G+ ++ C DGY L S
Sbjct: 895 THEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQ 954
Query: 3138 CEGRGVWKGEIPQC-----LPVFCG 3157
C+ W + C PV CG
Sbjct: 955 CQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 219 bits (559), Expect = 3e-56
Identities = 196/705 (27%), Positives = 292/705 (41%), Gaps = 96/705 (13%)
Query: 2732 PVCVPITCGHPGNPAHGFTN--GSEFNLNDVVNFTCNTGYLLQGVSRAQC----RSNGQW 2785
P + I+CG P +G + + + V+ ++C+ + L G C + +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 2786 SSPLPTCRVVN----CSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALT 2841
P P C N C +P G + +G S+ + CK F + G+ ++
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGST----PYRHGDSVTFACKTNFSMNGNKSVW 131
Query: 2842 CMANGLWDRS-LPKCLAI---SCGHPGVPA--NAVLTGE---LFTYGAVVHYSCRGSESL 2892
C AN +W + LP C+++ C P +P N T E G V YSC L
Sbjct: 132 CQANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLL 189
Query: 2893 IGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLLR------FS 2946
+G C WS P C C G +G K +LR F
Sbjct: 190 VGEKIINCLSSGKWSAVPPTC---EEARCKSLGRFPNGK-----VKEPPILRVGVTANFF 241
Query: 2947 CEMGHQLRGSPERTCLLNG---SWSGLQPVCEAVSCGNPGTPTNGMIVSSD--GILFSSS 3001
C+ G++L+G P C++ G +W+ + PVCE + C +P NG + + + + S
Sbjct: 242 CDEGYRLQGPPSSRCVIAGQGVAWTKM-PVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
Query: 3002 VIYAC----WEG--YKTSGLMTRHCTAN----GTWTGTAPDCTI----ISCGDPGTLANG 3047
V Y C EG + G T CT + GTW+G AP C + + C P L
Sbjct: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
Query: 3048 IQFGTD--FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQ 3105
+ G +T+N TV + C G+ ++ S IRC G W PS PVC+ C PP +
Sbjct: 361 MVSGQKDRYTYNDTVIFACMFGFTLKG--SKQIRCNAQGTWEPSAPVCEKE-CQAPPNIL 417
Query: 3106 NGTVEGSD---FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIP 3162
NG E F G+SI YSC GY L + C GVW +PQC C
Sbjct: 418 NGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC-----E 472
Query: 3163 AEGR--LSGKSFTY-KSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD 3219
A GR L+ + + +V C + L GS + CQ W C + TCP
Sbjct: 473 ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI---TCPP 529
Query: 3220 PGTPHFGIQNSS--RGYEVGSTVFFRCRKG------YHIQGSTTRTCLANL----TWSGI 3267
P + G S + G+TV + C G + + G +T C +N TWSG
Sbjct: 530 PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGP 589
Query: 3268 QTEC----IPHACRQPETPAHADVRAIDLPTF-GYTLVYTCHPGFFLAGGSEHRTCKADM 3322
C + C + + P F T+ + C+ GF L G S+ R CKAD
Sbjct: 590 APLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADN 648
Query: 3323 KWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKGYYEYLG 3367
W + PVC+ + + V +++ + P S V VN+ + Y+ G
Sbjct: 649 TWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 693
Score = 141 bits (356), Expect = 1e-32
Identities = 146/591 (24%), Positives = 236/591 (39%), Gaps = 83/591 (14%)
Query: 2257 KKCQPPPAVPQAEMLTEDDD---FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
K+CQ PP + + ED F+ G +KY C+PGY LVG + + C +S+ + +
Sbjct: 408 KECQAPPNILNGQK--EDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC--TSEGVWTPPV 463
Query: 2314 PTCE-AQCPA--NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
P C+ A C A ++ T + P + S S+ E I F++ +
Sbjct: 464 PQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFME-IRLC 522
Query: 2371 KQFDALEVFDGSSGQSPLLVVLSGNHTEQS--NFTSRSNQLY--------------LRWS 2414
K+ P V+ +G HT S +F + Y + S
Sbjct: 523 KEITC----------PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
Query: 2415 TDHATS---KKG--------FKIRYAAPYCSLTHPLKNGGILNRTAG-AVGSKVHYFCKP 2462
T TS ++G K+ A CS H I + A V + C
Sbjct: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 2463 GYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYEC 2522
G+ + G S C+ + WD P+C+ +C G+ L V C
Sbjct: 633 GFTLKGSSQIRCKAD----NTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL---VNTSC 685
Query: 2523 HEGFKLESSQQATAVCQ--EDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE 2580
+G++L + A +CQ E+G+W K P CK + C ++ + L
Sbjct: 686 QDGYQL--TGHAYQMCQDAENGIWFK--KIPLCKVIHCHPPPVIVNGKHTGMMAENFL-- 739
Query: 2581 YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNG-------- 2632
YG +V C G+YL G + L+C+++ + PS + + ++ PN
Sbjct: 740 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKL 799
Query: 2633 NKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAG---HCGSPDPIVN 2689
NK + + CN G+ + GS V C + W C+ C P N
Sbjct: 800 NKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPN 859
Query: 2690 GHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPA 2746
G+ +G FS +++Y C+ G+ LVG ++ +C + WS P C + C P +
Sbjct: 860 GNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-M 918
Query: 2747 HGFTNGSE----FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCR 2793
G G E + VV C GY+L+G ++QC+S+ QW+ PL CR
Sbjct: 919 DGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 96.7 bits (239), Expect = 4e-19
Identities = 87/336 (25%), Positives = 138/336 (41%), Gaps = 40/336 (11%)
Query: 3030 APDCTIISCGDPGTLANG--IQFGTDFTFNKTVSYQCNPGY--VMEAVTSATIRCTKDGR 3085
AP ISCG P + NG + T + Y C+ + + E + DG
Sbjct: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74
Query: 3086 WNPSKPVC----KAVLCPQPPPVQNGTVEGS-DFRWGSSISYSCMDGYQLSHSAILSCEG 3140
W+ P C K CP+P + GS +R G S++++C + ++ + + C+
Sbjct: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQA 134
Query: 3141 RGVW-KGEIPQCLPVFCGD-PGIPA--EGRLSGK---SFTYKSEVFFQCKSPFILVGSSR 3193
+W +P C+ VF + P +P G + + S V + C+S ++LVG
Sbjct: 135 NNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI 194
Query: 3194 RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGS 3253
C + G WS + PTC + C G G VG T F C +GY +QG
Sbjct: 195 INCLSSGKWSAVPPTCEEA---RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3254 TTRTCLANLTWSGIQTECIPHACRQ---PETPAHADVRAIDLP----TFGYTLVYTCHP- 3305
+ C+ + G+ +P C + P P + R I ++G + YTC P
Sbjct: 252 PSSRCV--IAGQGVAWTKMP-VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
Query: 3306 -----GFFLAGGSEHRTCKADMK----WTGKSPVCK 3332
F L G S R C D + W+G +P C+
Sbjct: 309 PEEGVNFILIGESTLR-CTVDSQKTGTWSGPAPRCE 343
Score = 75.9 bits (185), Expect = 7e-13
Identities = 222/1060 (20%), Positives = 362/1060 (34%), Gaps = 226/1060 (21%)
Query: 1564 ACFDPGNIMNG--TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPS 1621
+C P I+NG + T +G+ I Y C ++++ S+ C+ +WD+ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1622 CN-----APCGGQYT-GSEGVVLSPNYPHNYTAGQICL--YSITVPKEFVVFGQFAYFQT 1673
C + C G + S Y H + C +S+ K + T
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 1674 ALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFV--- 1730
L +F ++ +G H+ E + + + + + +S +SG G +
Sbjct: 142 RLPTCVSVFPLECPALPMIH--NGHHTSENVG-SIAPGLSVTYSCESGYLLVGEKIINCL 198
Query: 1731 ----YQAVPRT-SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTALHCQS 1784
+ AVP T + +C S+ G+ + G F C+ GY LQG + C
Sbjct: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 1785 VPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNL-NCIWKIIVT------E 1837
+A W + C F IL+ + GN+L N + IVT
Sbjct: 259 AGQGVA-WTK-----MPVCEEIFCPSPPPILNGRH---IGNSLANVSYGSIVTYTCDPDP 309
Query: 1838 GSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDI 1897
G+ +I +T + V + + G++SG L++++ Q
Sbjct: 310 EEGVNFILIGESTLR----------CTVDSQKTGTWSGPAPRCELSTSAVQ--------- 350
Query: 1898 SVAAAGFHLEYKTVGLAACQEPALPSNSIKIG--DRYMVNDVLSFQCEPGYTLQGRSHIS 1955
C P + + G DRY ND + F C G+TL+G I
Sbjct: 351 ------------------CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR 392
Query: 1956 C-MPGTVRRWNYPSPLCIATCGGTLSTLGG-------VILSPGFPGSYPNN--------- 1998
C GT W +P+C C + L G V PG Y N
Sbjct: 393 CNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
Query: 1999 -LDCT----WRISLPIGYGAHIQFL--NFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLP 2051
+ CT W +P A + T+ H F+ + G+ G L
Sbjct: 450 SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD-----VNSSCGE--GYKLS 502
Query: 2052 AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMINS---DYSVGQ 2108
++ T+ F + + + CP PP NG S D+ G
Sbjct: 503 GSVYQECQGTIPWF------------MEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGT 550
Query: 2109 SVSFECYPG------YILIGHPVLTCQHGINR--NWNYPFPRCDAPC------------G 2148
+V++ C PG + LIG + C W+ P P C G
Sbjct: 551 TVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANG 610
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN-DYIAVWDGP 2207
Y ++ + +P F ++ K Y FTL + + WD P
Sbjct: 611 YKISGKE----APYFYNDTVTFK-------------CYSGFTLKGSSQIRCKADNTWD-P 652
Query: 2208 D-------------QNSPQLGVFSG----NTALETAYSSTNQVLLKFHSDFSNGGFFVLN 2250
+ Q+ +L S NT+ + Y T + D NG +F
Sbjct: 653 EIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWF-KK 710
Query: 2251 FHAFQLKKCQPPPAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQ- 2306
++ C PPP + + M+ E +F G+ V Y+C G+ L+G L C+ S+
Sbjct: 711 IPLCKVIHCHPPPVIVNGKHTGMMAE--NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKG 768
Query: 2307 -LQFEGSLPTC-----EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNI 2360
+ G P C +CP EV+ G Y N C+ + + I
Sbjct: 769 HGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVI 828
Query: 2361 TIFVD-TFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHAT 2419
D T+ + F G P +GNHT N S + + +S D
Sbjct: 829 RCHTDNTWVPGVPTCIKKAFIGC---PPPPKTPNGNHT-GGNIARFSPGMSILYSCDQGY 884
Query: 2420 SKKGFKI---------RYAAPYC---SLTHPLKNGGILN----RTAGAVGSKVHYFCKPG 2463
G + AP+C + + P GI R G+ V C+ G
Sbjct: 885 LLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG 944
Query: 2464 YRMVGHSNATCRRNPLGMYQWDSLTPLCQA-----VSCGI 2498
Y + G + C+ + +QW+ +C++ V CGI
Sbjct: 945 YMLEGSPQSQCQSD----HQWNPPLAVCRSRSLAPVLCGI 980
Score = 72.0 bits (175), Expect = 1e-11
Identities = 194/895 (21%), Positives = 295/895 (32%), Gaps = 185/895 (20%)
Query: 143 HTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
HT N G I G+ + YSC GY+L G I+ C+ S W P C
Sbjct: 165 HTSENVGSIAPGL----------SVTYSCESGYLLVGEKIINCLSS----GKWSAVPPTC 210
Query: 203 RAEGACGGTLRGTSSSISS-PHFPSEYENNADCT--WTILAEPGDTIALVFTDFQLEEGY 259
E C R + + P N C + + P + +
Sbjct: 211 E-EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
Query: 260 DFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFN----AQFQVKKAI 315
EI P I L G ++ + + + + +T D + +G N + ++ +
Sbjct: 270 VCEEIFCPSPPPI-LNGRHIGNSLANVSYGSIVTYTCDPDPE-EGVNFILIGESTLRCTV 327
Query: 316 ELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGAN--VQ 373
+ + G + G LS V CP P I GR R N V
Sbjct: 328 DSQKTG-----TWSGPAPRCELSTSAV-----QCPHPQILR-GRMVSGQKDRYTYNDTVI 376
Query: 374 FSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYE 433
F+C + L+GSK I C W P+C + P ++ Q E
Sbjct: 377 FACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE-----KECQAPPNILNG-----QKE 422
Query: 434 DNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDL 493
D H V DP IK + + G +++ G V +
Sbjct: 423 DR-HMV----RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQ 477
Query: 494 IVSMSNQMWLHLQSDDSIGSPGFK---AVYQEIE-------------KGGCGDPGIPAYG 537
+++ ++ + S G G+K +VYQE + + C P + G
Sbjct: 478 LLTKPQHQFVRPDVNSSCGE-GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
Query: 538 KRTGSS---FLHGDTLTFECPAA------FELVGERVITCQQNNQ----WSGNKPSCVFS 584
TGSS F +G T+T+ C F L+GE I C N+Q WSG P C S
Sbjct: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
Query: 585 -----CFFNFTASSGIILSPNYPEEYGNNMN--CVWLIISEPGSRIHL-IFNDFDVEPQF 636
C A+ I P Y + + C + S+I N +D E
Sbjct: 597 LLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE--- 653
Query: 637 DFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQN 696
+ + + S E+P+ S +V Q + TG + + +N
Sbjct: 654 -IPVCEKETCQHVRQ----SLQELPA--GSRVELVNTSCQDGYQLTGHAYQMCQDA--EN 704
Query: 697 -------------ECHDPGIPINGRRFG---DRFLLGSSVSFHCDDGFVKTQGSESITCI 740
CH P + +NG+ G + FL G+ VS+ CD GF G + + C
Sbjct: 705 GIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCR 763
Query: 741 LQD-GNVVWSSTVP---------RCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEW--- 787
G+ WS P RC P H GY + H +
Sbjct: 764 SDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKH--------------GYKLNKTHSAYSHN 809
Query: 788 ---IIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPAS-SSPLIGEYHGTQAPQFLISTGN 843
++ PG I + D V P IG + P + GN
Sbjct: 810 DIVYVDCNPGF---IMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGN 866
Query: 844 F------MYLLFTTDNSRSSIGFLI--------------HYESVTLESDSCLDPGIPVNG 883
M +L++ D +G + H + V S + +D GI G
Sbjct: 867 IARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMD-GIQ-KG 924
Query: 884 HRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC------DALCG 932
+ + VT C+ GY L C+ +HQWN L C LCG
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 979
Score = 65.9 bits (159), Expect = 7e-10
Identities = 165/852 (19%), Positives = 285/852 (33%), Gaps = 162/852 (19%)
Query: 144 TCGNPGEILKGVL--HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
+CG+P IL G + + T +G IRYSC + L G L CI +WD PAP
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF-TDFQLEEGYD 260
C SS P P Y+ + GD++ T+F +
Sbjct: 82 CE--------YFNKYSSCPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGN-- 127
Query: 261 FLEISGTEAPSIWLTGMNLPSPV-------ISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
S+W N+ P + L + +H + +
Sbjct: 128 ---------KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLS 178
Query: 314 AIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDP-----GIPENGRRAGSDFSRV 368
G ++ G + LS G + V C + G NG+ RV
Sbjct: 179 VTYSCESGYLLV----GEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
Query: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY 428
G F C++ Y LQG S C + AW+ P+C C S P ++ +
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGRHI 288
Query: 429 PVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGS 488
+ ++ V T DPD E G + + +G+ S
Sbjct: 289 GNSLANVSYGSIVTYTCDPDP-----------EEGVNFILIGE----------------S 321
Query: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGD 548
++ + S W + + + + +I +G G++ + + D
Sbjct: 322 TLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRM------VSGQK--DRYTYND 373
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNN 608
T+ F C F L G + I C W + P C C + IL+ + +
Sbjct: 374 TVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC-----QAPPNILNGQKEDRH--- 425
Query: 609 MNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGI--SDITVLGTFSGNEVPSQLAS 666
++ +PG+ I N V + + +G+ + + QL +
Sbjct: 426 -----MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT 480
Query: 667 --SGHIVRLEFQSDHSTTGRGFNITYTTFGQNE----------------CHDPGIPINGR 708
VR + +S+ G G+ ++ + + + + C P + NG
Sbjct: 481 KPQHQFVRPDV---NSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA 537
Query: 709 RFG---DRFLLGSSVSFHCDDG-----FVKTQGSESITCILQD-GNVVWSSTVPRCE--- 756
G + F G++V++ C+ G G +I C D WS P C+
Sbjct: 538 HTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSL 597
Query: 757 --APCGGHLTASSGVILPPGWPGYYKDSL--HCEWIIEAKPGHSIKITFDR-FQTEV--- 808
C A+ I P +Y D++ C K I+ D + E+
Sbjct: 598 LAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC 657
Query: 809 -----NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIH 863
+ +++ PA S E T TG+ + +N I
Sbjct: 658 EKETCQHVRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENG-------IW 707
Query: 864 YESVTL-ESDSCLDPGIPVNGHRHG---GDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ 919
++ + L + C P + VNG G +F + V++ CD G+ L ++ L C + +
Sbjct: 708 FKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK 767
Query: 920 ----WNHALPSC 927
W+ P C
Sbjct: 768 GHGSWSGPSPQC 779
Score = 53.1 bits (126), Expect = 5e-06
Identities = 102/440 (23%), Positives = 171/440 (38%), Gaps = 76/440 (17%)
Query: 1062 FGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAECGASVKGNEGTLLSPN 1120
F G S+ +SC GY L G + C G VW+ P+P+C VA C A+ L P
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEAT---GRQLLTKPQ 483
Query: 1121 FPSNYDNNHECIYK-IETEAGKGIHLRTRSFQLFEGDT---LKVYDGKDSSSRPL----- 1171
H+ + + + G+G L +Q +G +++ K+ + P
Sbjct: 484 --------HQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
Query: 1172 GTFTKNEL----LGLILNSTSN---HLWLEFNTNG--------SDTDQGF-----QLTYT 1211
G T + L G + T N +EF+ G +D ++G L
Sbjct: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
Query: 1212 SFDLVKCEDPGIPNYGYRI--RDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDK 1269
S V+C I N GY+I ++ +F + V + C G+ + GS+ + C + + WD
Sbjct: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN--TWDP 652
Query: 1270 PLPSC-------IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWII-EADPG---KTIS 1318
+P C + + ++ A + +++ Y H + +A+ G K I
Sbjct: 653 EIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 1319 LHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTF-----NSLTLQFDSDF 1373
L ++ H + +G + G+ + + F L + DS
Sbjct: 713 LCKVIH----CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKG 768
Query: 1374 FISKSGFSIQFSTSIAAT-CNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAK 1429
S SG S Q S T C +P + ++G + + A D V C+PG+ + G
Sbjct: 769 HGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV 827
Query: 1430 ITCVQLNNRFFWQPDPPTCI 1449
I C N W P PTCI
Sbjct: 828 IRCHTDNT---WVPGVPTCI 844
Score = 52.0 bits (123), Expect = 1e-05
Identities = 179/829 (21%), Positives = 280/829 (33%), Gaps = 214/829 (25%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
CP+P +P + GS R G +V F+C+ N+ + G+KS+ W C+
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSV-----------W------CQ 133
Query: 409 ARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLT 468
A +N+ GP+ + T CV V P + + G+ T
Sbjct: 134 A----NNMWGPTRLPT-------------CVSVFPLECPALPM--------IHNGHHT-- 166
Query: 469 VGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSD---DSIGSPGFKAVYQEIEK 525
+ +V GS P L V+ S + L + + + S + AV E+
Sbjct: 167 ---------SENV-----GSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEE 212
Query: 526 GGCGDPGIPAYGKRTGSSFLH-GDTLTFECPAAFELVG---ERVITCQQNNQWSGNKPSC 581
C G GK L G T F C + L G R + Q W+ P C
Sbjct: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVC 271
Query: 582 VFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
F S IL+ + GN++ V GS + D D E +F+ +
Sbjct: 272 EEI----FCPSPPPILNGRH---IGNSLANV-----SYGSIVTYTC-DPDPEEGVNFILI 318
Query: 642 KDDGIS---DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNEC 698
+ + D GT+SG +L++S Q H RG ++ GQ
Sbjct: 319 GESTLRCTVDSQKTGTWSGPAPRCELSTSA------VQCPHPQILRGRMVS----GQK-- 366
Query: 699 HDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAP 758
DR+ +V F C GF +GS+ I C Q W + P CE
Sbjct: 367 -------------DRYTYNDTVIFACMFGFT-LKGSKQIRCNAQG---TWEPSAPVCEKE 409
Query: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
C PP K+ H ++ PG SIK + + V ++++
Sbjct: 410 CQA----------PPNILNGQKEDRH---MVRFDPGTSIKYSCNPGYVLVGEESIQCTSE 456
Query: 819 PASSSP----------------LIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLI 862
+ P L H P S G L + + G +
Sbjct: 457 GVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSV--YQECQGTIP 514
Query: 863 HYESVTLESD-SCLDPGIPVNGHRHGG---DFGIRSTVTFSCDPG------YTLSDDEPL 912
+ + L + +C P + NG G DF +TVT++C+PG ++L + +
Sbjct: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 913 VCERNHQ----WNHALPSCDA-----------LCGGY-IQGKSGTVLSPGFPDFYPNSLN 956
C N Q W+ P C + GY I GK P FY N
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEA-------PYFY----N 623
Query: 957 CTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGN 1016
T T + G F L+ S + D ++ + H ++
Sbjct: 624 DTVTFKCYSG---------FTLKGSSQ-IRCKADNTWDPEIPVCEKETCQHVRQS--LQE 671
Query: 1017 FTAQLRFISDFSISYEGFNITFSEYDLEP------------------CDDPGVPAFSRRI 1058
A R + +G+ +T Y + C P V +
Sbjct: 672 LPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHT 731
Query: 1059 GF---HFGVGDSLTFSCFLGYRLEGATKLTCLGG--GRRVWSAPLPRCV 1102
G +F G+ +++ C G+ L G KL C G WS P P+C+
Sbjct: 732 GMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 780
Score = 49.7 bits (117), Expect = 5e-05
Identities = 138/642 (21%), Positives = 214/642 (33%), Gaps = 126/642 (19%)
Query: 1038 FSEYDLEPCDDPGVPA-FSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSA 1096
F++Y C +P VP + R + GDS+TF+C + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
Query: 1097 P-LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
LP CV+ L P P ++ +H G + S L G
Sbjct: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 1156 DTLK--VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSF 1213
+ + + GK S+ P + + LG N
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNG--------------------------- 224
Query: 1214 DLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLP 1272
K ++P I G + C+ GY + G + C ++G W K +P
Sbjct: 225 ---KVKEPPILRVGVTAN-----------FFCDEGYRLQGPPSSRCVIAGQGVAWTK-MP 269
Query: 1273 SCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDT-EMAHD 1331
C +GR + A T+ + DP + ++ I T D
Sbjct: 270 VCEEIFCPSPPPILNGRHIGNSL-ANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1332 ILKV--WDGPVDSDILLKEWSGSALPEDIHSTFNS----LTLQFDSDFFISKSGFSIQFS 1385
K W GP L P+ + S D+ F GF+++ S
Sbjct: 329 SQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS 388
Query: 1386 TSIAATCN---DPGMP---------------QNGTRYGDSREAGDTVTFQCDPGYQLQGQ 1427
I +P P Q R+ + G ++ + C+PGY L G+
Sbjct: 389 KQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGE 448
Query: 1428 AKITCVQLNNRFFWQPDPPTC-IAACGGN----LTGPAGVILSPNYPQPYPPG------- 1475
I C + W P P C +AAC LT P + P+ G
Sbjct: 449 ESIQC---TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSV 505
Query: 1476 -KECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPL-------IGSYQGSQA 1527
+EC + P F+ + K P IY G + S L +Y +
Sbjct: 506 YQECQGTI---PWFMEIRLCKEITCPPP---PVIYNGAHTGSSLEDFPYGTTVTYTCNPG 559
Query: 1528 PER-IESS--GNSLFLAFRSDASVGL-SGFAIEFKEKPREACFDPGNIMNGTRVG---TD 1580
PER +E S G S +D G SG A K +I NG ++
Sbjct: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
Query: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
+ T+T++C SG+ + S I C AD +WD +P C
Sbjct: 620 YFYNDTVTFKCYSGFTLKGSSQIRC--KADN--TWDPEIPVC 657
Score = 39.7 bits (91), Expect = 0.054
Identities = 52/230 (22%), Positives = 86/230 (37%), Gaps = 28/230 (12%)
Query: 1239 TVVLYSCNPGYAMHGSNTLTCLSGDR--RVWDKPLPSCIAECGGQIHAATSGRILSPGY- 1295
TV+ YSC+ + + G +L C++ D+ WDKP P C E + +++ I+ GY
Sbjct: 45 TVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC--EYFNK-YSSCPEPIVPGGYK 101
Query: 1296 ---PAPYDN----NLHCTWIIEADPGKTISLHF-IVFDTEMAHDILKVWDGPVDSDILLK 1347
PY + C + K++ ++ + V+ P++ L
Sbjct: 102 IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF--PLECPALPM 159
Query: 1348 EWSGSALPEDIHSTFNSLTLQFDSDF-----------FISKSGFSIQFSTSIAATCNDPG 1396
+G E++ S L++ + + +S +S T A C G
Sbjct: 160 IHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLG 219
Query: 1397 MPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
NG + G T F CD GY+LQG CV W P
Sbjct: 220 RFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
Score = 33.5 bits (75), Expect = 3.9
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 1062 FGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
F G S+ +SC GY L G L C G WS P P C
Sbjct: 870 FSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHC 907
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 317 bits (811), Expect = 2e-85
Identities = 281/1002 (28%), Positives = 396/1002 (39%), Gaps = 116/1002 (11%)
Query: 2416 DHATSKKGFKIRYAAPYCSLTHPLKNGG--ILNRTAGAVGSKVHYFCKPGYRMVGHSNAT 2473
D K K Y Y S P+ GG I T G V + CK + M G+ +
Sbjct: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW 131
Query: 2474 CRRNPLGMYQWD-SLTPLCQAV---SCGIPESPGNGSFTGNE---FTLDSKVVYECHEGF 2526
C+ N + W + P C +V C NG T V Y C G+
Sbjct: 132 CQANNM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
Query: 2527 KLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE-----Y 2581
L + C G WS PPTC+ C S+ R +G + E
Sbjct: 188 LLVGEKIIN--CLSSGKWS--AVPPTCEEARCKSLG---------RFPNGKVKEPPILRV 234
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV- 2640
G C GY L+G RC G + P C I C S NG IG
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 2641 --YGATAIFTCN------TGYTLVGSHVRECLAN----GLWSGSETRC----LAGHCGSP 2684
YG+ +TC+ + L+G C + G WSG RC A C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 2685 DPIVNGHISG--DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
+ +SG D ++Y DTV++ C GF L G+ C W PVC C P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP 413
Query: 2743 GNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
N +G F+ + ++CN GY+L G QC S G W+ P+P C+V C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEA 473
Query: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAIS 2859
G + Q F + C +G+ L GS C W + C I+
Sbjct: 474 TG--RQLLTKPQHQFVRP-----DVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 2860 CGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGNDTRVC----QEDSHW 2906
C P V N TG E F YG V Y+C RG E SLIG T C QE W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLGD---DFKTKSLLRFSCEMGHQLRGSPERTCLL 2963
SG P C + A+G ++ + + F C G L+GS + C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSS--SVIYACWEGYKTSGLMTRHCT 3021
+ +W PVCE C +P +G + + F S +V Y C GY G + HC
Sbjct: 647 DNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM 705
Query: 3022 ANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCT 3081
+G W+ +AP C +C + G+ + V+ C GY + +
Sbjct: 706 PSGNWSPSAPRCE-ETCQHVRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDA 761
Query: 3082 KDGRWNPSKPVCKAVLCPQPPPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSC 3138
++G W P+CK + C PP + NG G +F +G+ +SY C G+ L L C
Sbjct: 762 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 821
Query: 3139 ----EGRGVWKGEIPQCL---PVF-CGDPGIPAEGRL--SGKSFTYKSEVFFQCKSPFIL 3188
+G G W G PQCL PV C +P + +L + ++++ V+ C FI+
Sbjct: 822 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 881
Query: 3189 VGSSRRVCQADGTWSGIQPTCIDPAHNTC-PDPGTP---HFGIQNSSRGYEVGSTVFFRC 3244
GS C D TW PTCI A C P P TP H G N +R + G ++ + C
Sbjct: 882 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG-GNIAR-FSPGMSILYSC 939
Query: 3245 RKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAID-------LPTFGY 3297
+GY + G C TWS + PH C++ + AD+ I + +G
Sbjct: 940 DQGYLLVGEALLLCTHEGTWS----QPAPH-CKEVNCSSPADMDGIQKGLEPRKMYQYGA 994
Query: 3298 TLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREV 3339
+ C G+ L GS C++D +W VC+S+ + V
Sbjct: 995 VVTLECEDGYMLE-GSPQSQCQSDHQWNPPLAVCRSRSLAPV 1035
Score = 308 bits (790), Expect = 5e-83
Identities = 273/1036 (26%), Positives = 424/1036 (40%), Gaps = 116/1036 (11%)
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQ--FEGSLPTC 2316
C PP + + +G ++Y C + L+G L C ++ ++ P C
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
Query: 2317 E-----AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV---DTFQ 2368
E + CP V G + P + +S T + N N +++ + +
Sbjct: 83 EYFNKYSSCPEPIV---PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
Query: 2369 SEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKI-- 2426
+ + VF + P L ++ H N S + L + +S + G KI
Sbjct: 140 PTRLPTCVSVF---PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
Query: 2427 -----RYAA-------PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATC 2474
+++A C NG + VG ++FC GYR+ G ++ C
Sbjct: 197 CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
Query: 2475 RRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEF---TLDSKVVYEC----HEGFK 2527
G+ W + P+C+ + C P NG GN + S V Y C EG
Sbjct: 257 VIAGQGV-AWTKM-PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 2528 L----ESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE--Y 2581
ES+ + T Q+ G WS G P C+ ++ +++ + + R+VSG + Y
Sbjct: 315 FILIGESTLRCTVDSQKTGTWS--GPAPRCE-LSTSAVQCPHPQILRGRMVSGQKDRYTY 371
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY 2641
V+ +C G+ L+G + +RC A GTW P C C + NG K V
Sbjct: 372 NDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEK-ECQAPPNILNGQKEDRHMVR 428
Query: 2642 ---GATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS 2698
G + ++CN GY LVG +C + G+W+ +C C + + ++
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQL---LTKPQHQ 485
Query: 2699 Y-RDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPG---NPAHGFTNGSE 2754
+ R V C G++L G+ + C W + +C ITC P N AH ++ +
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLED 545
Query: 2755 FNLNDVVNFTCNTG------YLLQGVSRAQCRSN----GQWSSPLPTCRV----VNCSDP 2800
F V +TCN G + L G S +C SN G WS P P C++ V CS
Sbjct: 546 FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
Query: 2801 GFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISC 2860
+ N + + P + Y ++ + C GF L GSS + C A+ WD +P C
Sbjct: 606 -HIANGYKISGKEAP--YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
Query: 2861 GHPGVPANAVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNP 2918
PG+ G F G V Y+C L+GN + C +WS + P C
Sbjct: 663 SPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ 722
Query: 2919 GFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTC--LLNGSWSGLQPVCEA 2976
GSR+ L+ SC+ G+QL G + C NG W P+C+
Sbjct: 723 HVRQSLQELPAGSRV-------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Query: 2977 VSCGNPGTPTNGMI--VSSDGILFSSSVIYACWEGYKTSGLMTRHCTA----NGTWTGTA 3030
+ C P NG + ++ L+ + V Y C +G+ G C + +G+W+G +
Sbjct: 776 IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 835
Query: 3031 PDC----TIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPGYVMEAVTSATIRCTKD 3083
P C + C +P + +G + + ++ N V CNPG++M S IRC D
Sbjct: 836 PQCLRSPPVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG--SRVIRCHTD 892
Query: 3084 GRWNPSKPVC--KAVL-CPQPPPVQNGTVEGSD---FRWGSSISYSCMDGYQLSHSAILS 3137
W P P C KA + CP PP NG G + F G SI YSC GY L A+L
Sbjct: 893 NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL 952
Query: 3138 CEGRGVWKGEIPQCLPVFCGDP----GIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR 3193
C G W P C V C P GI +G K + Y + V +C+ ++L GS +
Sbjct: 953 CTHEGTWSQPAPHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQ 1011
Query: 3194 RVCQADGTWSGIQPTC 3209
CQ+D W+ C
Sbjct: 1012 SQCQSDHQWNPPLAVC 1027
Score = 196 bits (497), Expect = 5e-49
Identities = 147/512 (28%), Positives = 215/512 (41%), Gaps = 64/512 (12%)
Query: 2453 GSKVHYFCKPG------YRMVGHSNATCRRNPLGMYQWDSLTPLCQ----AVSCGIPESP 2502
G+ V Y C PG + ++G S C N W PLC+ AV C
Sbjct: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIA 608
Query: 2503 GNGSFTGNE--FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPS 2560
+G E + + V ++C+ GF L+ S Q C+ D W + P C+
Sbjct: 609 NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR--CKADNTWDPE--IPVCEKGCQSP 664
Query: 2561 IEAQLSEHVIWR---LVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDER-- 2615
H VSG +Y +C PGY L G + + C +G W+ R
Sbjct: 665 PGLHHGRHTGGNTVFFVSGMTVDY------TCDPGYLLVGNKSIHCMPSGNWSPSAPRCE 718
Query: 2616 PSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVREC--LANGLWSGSE 2673
+C+ + SL P G+++ + +C GY L G + C NG+W
Sbjct: 719 ETCQHVR-QSLQELPAGSRVELVNT-------SCQDGYQLTGHAYQMCQDAENGIWFKKI 770
Query: 2674 TRCLAGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHK---- 2726
C HC P IVNG +G + F Y + V Y+C+ GF L+G C D K
Sbjct: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
Query: 2727 WSGQTPVCV---PIT-CGHPGNPAHGFT---NGSEFNLNDVVNFTCNTGYLLQGVSRAQC 2779
WSG +P C+ P+T C +P HG+ S ++ ND+V CN G+++ G +C
Sbjct: 831 WSGPSPQCLRSPPVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC 889
Query: 2780 RSNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLG 2836
++ W +PTC + C P N H N F GMSILY C +G+ L+G
Sbjct: 890 HTDNTWVPGVPTCIKKAFIGCPPPPKTPNG-NHTGGNIAR-FSPGMSILYSCDQGYLLVG 947
Query: 2837 SSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTG----ELFTYGAVVHYSCRGSESL 2892
+ L C G W + P C ++C P + + G +++ YGAVV C L
Sbjct: 948 EALLLCTHEGTWSQPAPHCKEVNCSSP-ADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 1006
Query: 2893 IGNDTRVCQEDSHWSGALPHCTGNN--PGFCG 2922
G+ CQ D W+ L C + P CG
Sbjct: 1007 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 195 bits (496), Expect = 6e-49
Identities = 155/562 (27%), Positives = 229/562 (40%), Gaps = 61/562 (10%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMA----NGLWDRSLPKCLAI----SCGHPGVPANAVLT 2872
G I Y C F L+G +L C+ +G WD+ PKC SC P VP +
Sbjct: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIR 103
Query: 2873 GEL-FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGA-LPHCTGNNPGFCGDPGTPA-- 2928
G + +G V ++C+ + S+ GN + CQ ++ W LP C P C P P
Sbjct: 104 GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLEC--PALPMIH 161
Query: 2929 ---HGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTP 2985
H S + +SCE G+ L G CL +G WS + P CE C + G
Sbjct: 162 NGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRF 221
Query: 2986 TNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANG---TWTGTAPDCTIISCGDPG 3042
NG + + + + C EGY+ G + C G WT P C I C P
Sbjct: 222 PNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPP 280
Query: 3043 TLANGIQFG---TDFTFNKTVSYQCNP----GYVMEAVTSATIRCT----KDGRWNPSKP 3091
+ NG G + ++ V+Y C+P G + +T+RCT K G W+ P
Sbjct: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
Query: 3092 VCK----AVLCPQPPPVQNGTVEGSD--FRWGSSISYSCMDGYQLSHSAILSCEGRGVWK 3145
C+ AV CP P ++ V G + + ++ ++CM G+ L S + C +G W+
Sbjct: 341 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWE 400
Query: 3146 GEIPQCLPVFCGDPGIPAEGRLSGK---SFTYKSEVFFQCKSPFILVGSSRRVCQADGTW 3202
P C P I G+ + F + + + C ++LVG C ++G W
Sbjct: 401 PSAPVCEKECQAPPNI-LNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
Query: 3203 SGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANL 3262
+ P C A C G + + V V C +GY + GS + C +
Sbjct: 460 TPPVPQCKVAA---CEATGRQ---LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTI 513
Query: 3263 TWSGIQTECIPHACRQPE---TPAHADVRAIDLPTFGYTLVYTCHPG------FFLAGGS 3313
W C C P AH D P +G T+ YTC+PG F L G S
Sbjct: 514 PWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP-YGTTVTYTCNPGPERGVEFSLIGES 572
Query: 3314 EHRTCKADMK---WTGKSPVCK 3332
R D + W+G +P+CK
Sbjct: 573 TIRCTSNDQERGTWSGPAPLCK 594
Score = 172 bits (435), Expect = 7e-42
Identities = 175/658 (26%), Positives = 267/658 (40%), Gaps = 97/658 (14%)
Query: 2257 KKCQPPPAVPQAEMLTEDDD---FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
K+CQ PP + + ED F+ G +KY C+PGY LVG + + C +S+ + +
Sbjct: 408 KECQAPPNILNGQK--EDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC--TSEGVWTPPV 463
Query: 2314 PTCE-AQCPA--NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
P C+ A C A ++ T + P + S S+ E I F++ +
Sbjct: 464 PQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFME-IRLC 522
Query: 2371 KQFDALEVFDGSSGQSPLLVVLSGNHTEQS--NFTSRSNQLY--------------LRWS 2414
K+ P V+ +G HT S +F + Y + S
Sbjct: 523 KEITC----------PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
Query: 2415 TDHATS---KKG--------FKIRYAAPYCSLTHPLKNGGILNRTAG-AVGSKVHYFCKP 2462
T TS ++G K+ A CS H I + A V + C
Sbjct: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 2463 GYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVV 2519
G+ + G S C+ + WD P+C+ C P +G TG F V
Sbjct: 633 GFTLKGSSQIRCKAD----NTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVD 687
Query: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
Y C G+ L ++ + C G WS P C+ C + L E L +GS
Sbjct: 688 YTCDPGYLLVGNK--SIHCMPSGNWSPSA--PRCEE-TCQHVRQSLQE-----LPAGSRV 737
Query: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQ--ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGT 2637
E V SC GY L G CQ NG W + P C+VI C NG G
Sbjct: 738 EL---VNTSCQDGYQLTGHAYQMCQDAENGIW--FKKIPLCKVIHCHPPPVIVNGKHTGM 792
Query: 2638 LT---VYGATAIFTCNTGYTLVGSHVRECLA----NGLWSGSETRCLAG----HCGSPDP 2686
+ +YG + C+ G+ L+G +C + +G WSG +CL C +P+
Sbjct: 793 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE- 851
Query: 2687 IVNGH---ISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVP---ITCG 2740
+ +G+ + +S+ D V CNPGF + G+ V C D+ W P C+ I C
Sbjct: 852 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
Query: 2741 HPGNPAHGFTNG---SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNC 2797
P +G G + F+ + ++C+ GYLL G + C G WS P P C+ VNC
Sbjct: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
Query: 2798 SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
S P ++ I+ G + + ++YG + C+ G+ L GS C ++ W+ L C
Sbjct: 972 SSPADMD-GIQKGLEP-RKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 96.7 bits (239), Expect = 4e-19
Identities = 87/336 (25%), Positives = 138/336 (41%), Gaps = 40/336 (11%)
Query: 3030 APDCTIISCGDPGTLANG--IQFGTDFTFNKTVSYQCNPGY--VMEAVTSATIRCTKDGR 3085
AP ISCG P + NG + T + Y C+ + + E + DG
Sbjct: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74
Query: 3086 WNPSKPVC----KAVLCPQPPPVQNGTVEGS-DFRWGSSISYSCMDGYQLSHSAILSCEG 3140
W+ P C K CP+P + GS +R G S++++C + ++ + + C+
Sbjct: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQA 134
Query: 3141 RGVW-KGEIPQCLPVFCGD-PGIPA--EGRLSGK---SFTYKSEVFFQCKSPFILVGSSR 3193
+W +P C+ VF + P +P G + + S V + C+S ++LVG
Sbjct: 135 NNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI 194
Query: 3194 RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGS 3253
C + G WS + PTC + C G G VG T F C +GY +QG
Sbjct: 195 INCLSSGKWSAVPPTCEEA---RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 3254 TTRTCLANLTWSGIQTECIPHACRQ---PETPAHADVRAIDLP----TFGYTLVYTCHP- 3305
+ C+ + G+ +P C + P P + R I ++G + YTC P
Sbjct: 252 PSSRCV--IAGQGVAWTKMP-VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
Query: 3306 -----GFFLAGGSEHRTCKADMK----WTGKSPVCK 3332
F L G S R C D + W+G +P C+
Sbjct: 309 PEEGVNFILIGESTLR-CTVDSQKTGTWSGPAPRCE 343
Score = 82.4 bits (202), Expect = 7e-15
Identities = 149/671 (22%), Positives = 236/671 (35%), Gaps = 140/671 (20%)
Query: 1217 KCEDPGIPNYGYRIRDEGHFT----DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLP 1272
+C+ P PN +++ H T + YSCNPGY + G ++ C S VW P+P
Sbjct: 409 ECQAP--PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTS--EGVWTPPVP 464
Query: 1273 SC-IAEC---GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM 1328
C +A C G Q+ + + P + + + + TI M
Sbjct: 465 QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWF-------M 517
Query: 1329 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSI 1388
+ K P I +GS+L + + T + T + + FS+ ++I
Sbjct: 518 EIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVE---FSLIGESTI 574
Query: 1389 AATCNDPGMPQNGTRYGDS-------------------------REA----GDTVTFQCD 1419
T ND + GT G + +EA DTVTF+C
Sbjct: 575 RCTSNDQ---ERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY 631
Query: 1420 PGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECD 1479
G+ L+G ++I C N W P+ P C C PPG
Sbjct: 632 SGFTLKGSSQIRCKADNT---WDPEIPVCEKGCQS------------------PPGLHHG 670
Query: 1480 WRVKVNPDFVIALIFKSFNMEPSY-----DFLHIYEG----------EDSNSPLIGSYQG 1524
N F ++ + + +P Y +H E++ + S Q
Sbjct: 671 RHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQE 730
Query: 1525 SQAPERIESSGNSLFLAFR---------SDASVGLSGFAIEFKEKPREA---CFDPGNIM 1572
A R+E S ++ DA G I FK+ P C P I+
Sbjct: 731 LPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENG-----IWFKKIPLCKVIHCHPPPVIV 785
Query: 1573 NGTRVGT---DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC-NAPCGG 1628
NG G +F G+ ++Y+CD G+ +L + C + G SW P C +P
Sbjct: 786 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
Query: 1629 QYTGSE---GVVLSPN---YPHNYTAGQICLYSITVPKEFVV--FGQFAYFQTALNDLAE 1680
+ E G L+ Y HN C + V+ + + +
Sbjct: 846 RCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKK 905
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVY--------Q 1732
F G + + +G+H+G + + +L +S G G + Q
Sbjct: 906 AFIGCPPPPK---TPNGNHTGGNIARFSPGMSIL-YSCDQGYLLVGEALLLCTHEGTWSQ 961
Query: 1733 AVPRTSDTQCSSVPEPRYGRRIGSE----FSAGSIVRFECNPGYLLQGSTALHCQSVPNA 1788
P + CSS P G + G E + G++V EC GY+L+GS CQS
Sbjct: 962 PAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSD--- 1017
Query: 1789 LAQWNDTIPSC 1799
QWN + C
Sbjct: 1018 -HQWNPPLAVC 1027
Score = 74.7 bits (182), Expect = 2e-12
Identities = 140/663 (21%), Positives = 229/663 (34%), Gaps = 123/663 (18%)
Query: 1565 CFDPGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADG-----KPSWDQV 1618
C G NG + ++G T + CD GY++ P S CVI G P +++
Sbjct: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEI 274
Query: 1619 L-PSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKE----FVVFGQFAYFQT 1673
PS G++ G N N + G I Y+ E F++ G+ T
Sbjct: 275 FCPSPPPILNGRHIG--------NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326
Query: 1674 ALNDLAELFDGTHAQARLLSS--------------LSGSHS----GETLPLATSNQILLR 1715
+ + G + L +S +SG +T+ A L+
Sbjct: 327 VDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK 386
Query: 1716 FSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSE---FSAGSIVRFECNPGY 1772
S + +A+G ++ + +C + P G++ F G+ +++ CNPGY
Sbjct: 387 GSKQIRCNAQG---TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 1773 LLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGN----FTQRRGTILSPGYPEPYGNNL 1827
+L G ++ C S W +P C V C T+ + + P G
Sbjct: 444 VLVGEESIQCTSE----GVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY 499
Query: 1828 NCIWKII-VTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFS-GTTVPALLN-S 1884
+ +G+ I E + G T L F GTTV N
Sbjct: 500 KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPG 559
Query: 1885 TSNQLYLHFQSDISVAAAGFHLEYKT---------VGLAACQ-EPALPSNSIKIGDR--- 1931
+ + ++ E T + L A Q +N KI +
Sbjct: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
Query: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC-------------GGT 1978
Y ND ++F+C G+TL+G S I C W+ P+C C G T
Sbjct: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADNT--WDPEIPVCEKGCQSPPGLHHGRHTGGNT 677
Query: 1979 LSTLGGVIL----SPGFPGSYPNNLDC----TWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
+ + G+ + PG+ ++ C W S P H
Sbjct: 678 VFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAP----------RCEETCQHVRQS 727
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYS--DHSQNRQGFKLAYQAYELQNC 2088
+Q P S +L ++ H Y ++N FK ++ +C
Sbjct: 728 LQELP--------AGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK-KIPLCKVIHC 778
Query: 2089 PDPPPFQNGY---MINSDYSVGQSVSFECYPGYILIGHPVLTCQ-----HGINRNWNYPF 2140
PP NG M+ ++ G VS+EC G+ L+G L C+ HG +W+ P
Sbjct: 779 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPS 835
Query: 2141 PRC 2143
P+C
Sbjct: 836 PQC 838
Score = 66.2 bits (160), Expect = 5e-10
Identities = 173/830 (20%), Positives = 273/830 (32%), Gaps = 142/830 (17%)
Query: 1038 FSEYDLEPCDDPGVPA-FSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSA 1096
F++Y C +P VP + R + GDS+TF+C + + G + C +W
Sbjct: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
Query: 1097 P-LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
LP CV+ L P P ++ +H G + S L G
Sbjct: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
Query: 1156 DTLK--VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSF 1213
+ + + GK S+ P + + LG N
Sbjct: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNG--------------------------- 224
Query: 1214 DLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLP 1272
K ++P I G + C+ GY + G + C ++G W K +P
Sbjct: 225 ---KVKEPPILRVGVTAN-----------FFCDEGYRLQGPPSSRCVIAGQGVAWTK-MP 269
Query: 1273 SCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDT-EMAHD 1331
C +GR + A T+ + DP + ++ I T D
Sbjct: 270 VCEEIFCPSPPPILNGRHIGNSL-ANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
Query: 1332 ILKV--WDGPVDSDILLKEWSGSALPEDIHSTFNS----LTLQFDSDFFISKSGFSIQFS 1385
K W GP L P+ + S D+ F GF+++ S
Sbjct: 329 SQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS 388
Query: 1386 TSIAATCN---DPGMP---------------QNGTRYGDSREAGDTVTFQCDPGYQLQGQ 1427
I +P P Q R+ + G ++ + C+PGY L G+
Sbjct: 389 KQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGE 448
Query: 1428 AKITCVQLNNRFFWQPDPPTC-IAACGGN----LTGPAGVILSPNYPQPYPPG------- 1475
I C + W P P C +AAC LT P + P+ G
Sbjct: 449 ESIQC---TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSV 505
Query: 1476 -KECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPL-------IGSYQGSQA 1527
+EC + P F+ + K P IY G + S L +Y +
Sbjct: 506 YQECQGTI---PWFMEIRLCKEITCPPP---PVIYNGAHTGSSLEDFPYGTTVTYTCNPG 559
Query: 1528 PER-IESS--GNSLFLAFRSDASVGL-SGFAIEFKEKPREACFDPGNIMNGTRVG---TD 1580
PER +E S G S +D G SG A K +I NG ++
Sbjct: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
Query: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPC-------GGQYTGS 1633
+ T+T++C SG+ + S I C AD +WD +P C C G++TG
Sbjct: 620 YFYNDTVTFKCYSGFTLKGSSQIRC--KADN--TWDPEIPVCEKGCQSPPGLHHGRHTGG 675
Query: 1634 EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS 1693
V +YT L + G ++ + + H + L
Sbjct: 676 NTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ-----HVRQSLQE 730
Query: 1694 SLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRR 1753
+GS E + + + L A ++ +P C P G+
Sbjct: 731 LPAGSRV-ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
Query: 1754 IG---SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV 1800
G F G+ V +EC+ G+ L G L C+S W+ P C+
Sbjct: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
Score = 63.5 bits (153), Expect = 3e-09
Identities = 94/457 (20%), Positives = 151/457 (33%), Gaps = 83/457 (18%)
Query: 144 TCGNPGEILKGVL--HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
+CG+P IL G + + T +G IRYSC + L G L CI +WD PAP
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF-TDFQLEEGYD 260
C SS P P Y+ + GD++ T+F +
Sbjct: 82 CE--------YFNKYSSCPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGN-- 127
Query: 261 FLEISGTEAPSIWLTGMNLPSPV-------ISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
S+W N+ P + L + +H + +
Sbjct: 128 ---------KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLS 178
Query: 314 AIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDP-----GIPENGRRAGSDFSRV 368
G ++ G + LS G + V C + G NG+ RV
Sbjct: 179 VTYSCESGYLLV----GEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
Query: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY 428
G F C++ Y LQG S C + AW+ P+C C S P ++ +
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGRHI 288
Query: 429 PVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGS 488
+ ++ V T DPD E G + + +G+ S
Sbjct: 289 GNSLANVSYGSIVTYTCDPDP-----------EEGVNFILIGE----------------S 321
Query: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGD 548
++ + S W + + + + +I +G G++ + + D
Sbjct: 322 TLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRM------VSGQK--DRYTYND 373
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
T+ F C F L G + I C W + P C C
Sbjct: 374 TVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
Score = 63.5 bits (153), Expect = 3e-09
Identities = 111/513 (21%), Positives = 177/513 (34%), Gaps = 110/513 (21%)
Query: 145 CGNPGEILKGVL---HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
C P IL G H RF+ G I+YSC PGY+L G + C + W P P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT----SEGVWTPPVPQ 465
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDF 261
C+ AC T G H + N+ C G+ L G +
Sbjct: 466 CKV-AACEAT--GRQLLTKPQHQFVRPDVNSSC--------GEGYKL--------SGSVY 506
Query: 262 LEISGTEAPSIWLTGMNL-------PSPVISSKNWLRLHFTSDSNHRRKGFNAQFQV--- 311
E GT W + L P PVI + H S G +
Sbjct: 507 QECQGTIP---WFMEIRLCKEITCPPPPVIYNG----AHTGSSLEDFPYGTTVTYTCNPG 559
Query: 312 -KKAIELKSRGVKMLPSKDGSHKNSVLSQGG----VALVSDMCPDPGIPENGRRAGSDFS 366
++ +E G + + S ++L++ C I + +G +
Sbjct: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
Query: 367 RV-GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRA------------RTCG 413
V F C + L+GS I C+ W P+C T G
Sbjct: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCEKGCQSPPGLHHGRHTGG 675
Query: 414 SNLRGPSGVITS----PNYPVQYEDNAHCV----WVITTTDPDKVIKLAFEEF-ELERGY 464
+ + SG+ P Y + + HC+ W + ++ + + EL G
Sbjct: 676 NTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGS 735
Query: 465 DTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIE 524
V + + G Y LTG + + N +W P K ++
Sbjct: 736 RVELVNTSCQDG------YQLTGHAY-QMCQDAENGIWFKK-------IPLCKVIH---- 777
Query: 525 KGGCGDPGIPAYGKRTG---SSFLHGDTLTFECPAAFELVGERVITCQQNNQ----WSGN 577
C P + GK TG +FL+G+ +++EC F L+GE+ + C+ +++ WSG
Sbjct: 778 ---CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
Query: 578 KPSCVFSCFFNFTASSGIILSPNYPEEYGNNMN 610
P C+ S + PN ++G +N
Sbjct: 835 SPQCL--------RSPPVTRCPNPEVKHGYKLN 859
Score = 62.0 bits (149), Expect = 1e-08
Identities = 151/692 (21%), Positives = 223/692 (32%), Gaps = 171/692 (24%)
Query: 349 CPDPGIPENGRRAGSDFSRV--GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPI 406
C P NG++ R G ++++SC YVL G +SI C + W+ P
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT----SEGVWTPPVPQ 465
Query: 407 CRARTCGSNLRGPSGVITSPNYP-VQYEDNAHC------------------VWV------ 441
C+ C + R ++T P + V+ + N+ C W
Sbjct: 466 CKVAACEATGRQ---LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLC 522
Query: 442 --ITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
IT P + A LE TV G R V + L G S I SN
Sbjct: 523 KEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGEST---IRCTSN 579
Query: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSS--FLHGDTLTFECPAA 557
S + P K ++ C I K +G + + DT+TF+C +
Sbjct: 580 DQERGTWSGPA---PLCKLSLLAVQ---CSHVHIANGYKISGKEAPYFYNDTVTFKCYSG 633
Query: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
F L G I C+ +N W P C G P N V+ +
Sbjct: 634 FTLKGSSQIRCKADNTWDPEIPVC----------EKGCQSPPGLHHGRHTGGNTVFFV-- 681
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-------------- 663
G + D+ +P +L V + I + SGN PS
Sbjct: 682 -SGMTV-----DYTCDP--GYLLVGNKSIHCMP-----SGNWSPSAPRCEETCQHVRQSL 728
Query: 664 ----LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQN-------------ECHDPGIPIN 706
S +V Q + TG + + +N CH P + +N
Sbjct: 729 QELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA--ENGIWFKKIPLCKVIHCHPPPVIVN 786
Query: 707 GRRFG---DRFLLGSSVSFHCDDGFVKTQGSESITCILQD-GNVVWSSTVP--------- 753
G+ G + FL G+ VS+ CD GF G + + C G+ WS P
Sbjct: 787 GKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
Query: 754 RCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEW------IIEAKPGHSIKITFDRFQTE 807
RC P H GY + H + ++ PG I
Sbjct: 846 RCPNPEVKH--------------GYKLNKTHSAYSHNDIVYVDCNPGF---IMNGSRVIR 888
Query: 808 VNYDTLEVRDGPAS-SSPLIGEYHGTQAPQFLISTGNF------MYLLFTTDNSRSSIGF 860
+ D V P IG + P + GN M +L++ D +G
Sbjct: 889 CHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 948
Query: 861 LI--------------HYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTL 906
+ H + V S + +D GI G + + VT C+ GY L
Sbjct: 949 ALLLCTHEGTWSQPAPHCKEVNCSSPADMD-GIQ-KGLEPRKMYQYGAVVTLECEDGYML 1006
Query: 907 SDDEPLVCERNHQWNHALPSC------DALCG 932
C+ +HQWN L C LCG
Sbjct: 1007 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
Score = 59.7 bits (143), Expect = 5e-08
Identities = 135/643 (20%), Positives = 221/643 (34%), Gaps = 134/643 (20%)
Query: 1564 ACFDPGNIMNG--TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPS 1621
+C P I+NG + T +G+ I Y C ++++ S+ C+ +WD+ P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 1622 CN-----APCGGQYT-GSEGVVLSPNYPHNYTAGQICL--YSITVPKEFVVFGQFAYFQT 1673
C + C G + S Y H + C +S+ K + T
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 1674 ALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFV--- 1730
L +F ++ +G H+ E + + + + + +S +SG G +
Sbjct: 142 RLPTCVSVFPLECPALPMIH--NGHHTSENVG-SIAPGLSVTYSCESGYLLVGEKIINCL 198
Query: 1731 ----YQAVPRT-SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTALHCQS 1784
+ AVP T + +C S+ G+ + G F C+ GY LQG + C
Sbjct: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 1785 VPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNL-NCIWKIIVT------E 1837
+A W + C F IL+ + GN+L N + IVT
Sbjct: 259 AGQGVA-WTK-----MPVCEEIFCPSPPPILNGRH---IGNSLANVSYGSIVTYTCDPDP 309
Query: 1838 GSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDI 1897
G+ +I +T + V + + G++SG L++++ Q
Sbjct: 310 EEGVNFILIGESTLR----------CTVDSQKTGTWSGPAPRCELSTSAVQ--------- 350
Query: 1898 SVAAAGFHLEYKTVGLAACQEPALPSNSIKIG--DRYMVNDVLSFQCEPGYTLQGRSHIS 1955
C P + + G DRY ND + F C G+TL+G I
Sbjct: 351 ------------------CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR 392
Query: 1956 C-MPGTVRRWNYPSPLCIATCGGTLSTLGG-------VILSPGFPGSYPNN--------- 1998
C GT W +P+C C + L G V PG Y N
Sbjct: 393 CNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
Query: 1999 -LDCT----WRISLPIGYGAHIQFL--NFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLP 2051
+ CT W +P A + T+ H F+ + G+ G L
Sbjct: 450 SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD-----VNSSCGE--GYKLS 502
Query: 2052 AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMINS---DYSVGQ 2108
++ T+ F + + + CP PP NG S D+ G
Sbjct: 503 GSVYQECQGTIPWF------------MEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGT 550
Query: 2109 SVSFECYPG------YILIGHPVLTCQHGINR--NWNYPFPRC 2143
+V++ C PG + LIG + C W+ P P C
Sbjct: 551 TVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
Score = 54.3 bits (129), Expect = 2e-06
Identities = 108/480 (22%), Positives = 164/480 (34%), Gaps = 86/480 (17%)
Query: 143 HTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
HT N G I G+ + YSC GY+L G I+ C+ S W P C
Sbjct: 165 HTSENVGSIAPGL----------SVTYSCESGYLLVGEKIINCLSS----GKWSAVPPTC 210
Query: 203 RAEGACGGTLRGTSSSISS-PHFPSEYENNADCT--WTILAEPGDTIALVFTDFQLEEGY 259
E C R + + P N C + + P + +
Sbjct: 211 E-EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
Query: 260 DFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFN----AQFQVKKAI 315
EI P I L G ++ + + + + +T D + +G N + ++ +
Sbjct: 270 VCEEIFCPSPPPI-LNGRHIGNSLANVSYGSIVTYTCDPDPE-EGVNFILIGESTLRCTV 327
Query: 316 ELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGAN--VQ 373
+ + G + G LS V CP P I GR R N V
Sbjct: 328 DSQKTG-----TWSGPAPRCELSTSAV-----QCPHPQILR-GRMVSGQKDRYTYNDTVI 376
Query: 374 FSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYE 433
F+C + L+GSK I C W P+C + P ++ Q E
Sbjct: 377 FACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE-----KECQAPPNILNG-----QKE 422
Query: 434 DNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDL 493
D H V DP IK + + G +++ G V +
Sbjct: 423 DR-HMV----RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQ 477
Query: 494 IVSMSNQMWLHLQSDDSIGSPGFK---AVYQEIE-------------KGGCGDPGIPAYG 537
+++ ++ + S G G+K +VYQE + + C P + G
Sbjct: 478 LLTKPQHQFVRPDVNSSCGE-GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
Query: 538 KRTGSS---FLHGDTLTFECPAA------FELVGERVITCQQNNQ----WSGNKPSCVFS 584
TGSS F +G T+T+ C F L+GE I C N+Q WSG P C S
Sbjct: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
Score = 54.3 bits (129), Expect = 2e-06
Identities = 98/448 (21%), Positives = 156/448 (34%), Gaps = 102/448 (22%)
Query: 2086 QNCPDPPPFQNGYMINSD---YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPR 2142
+ C PP +G + + G +V + C PGY+L+G+ + C + NW+ PR
Sbjct: 659 KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP--SGNWSPSAPR 716
Query: 2143 CDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIA 2202
C+ C + S L +P G V E VN
Sbjct: 717 CEETCQHVRQS----------------------LQELPAGSRV---------ELVN---- 741
Query: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPP 2262
T+ + Y T + D NG +F ++ C PP
Sbjct: 742 ------------------TSCQDGYQLTGHA-YQMCQDAENGIWF-KKIPLCKVIHCHPP 781
Query: 2263 PAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQ--LQFEGSLPTC- 2316
P + + M+ E +F G+ V Y+C G+ L+G L C+ S+ + G P C
Sbjct: 782 PVIVNGKHTGMMAE--NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
Query: 2317 ----EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVD-TFQSEK 2371
+CP EV+ G Y N C+ + + I D T+
Sbjct: 840 RSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGV 899
Query: 2372 QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKI----- 2426
+ F G P +GNHT N S + + +S D G +
Sbjct: 900 PTCIKKAFIGC---PPPPKTPNGNHT-GGNIARFSPGMSILYSCDQGYLLVGEALLLCTH 955
Query: 2427 ----RYAAPYC---SLTHPLKNGGILN----RTAGAVGSKVHYFCKPGYRMVGHSNATCR 2475
AP+C + + P GI R G+ V C+ GY + G + C+
Sbjct: 956 EGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 1015
Query: 2476 RNPLGMYQWDSLTPLCQA-----VSCGI 2498
+ +QW+ +C++ V CGI
Sbjct: 1016 SD----HQWNPPLAVCRSRSLAPVLCGI 1039
Score = 44.7 bits (104), Expect = 0.002
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 89/445 (20%)
Query: 892 IRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSPGFPDF 950
+R V SC GY LS C+ W + C + C +G DF
Sbjct: 487 VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
Query: 951 YPNSLNCTWTIEVSHGKGVQ--MIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLP-- 1006
P T+T +GV+ +I + +S+D E G++S P S+L
Sbjct: 547 -PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQ----ERGTWSGPAPLCKLSLLAVQ 601
Query: 1007 --HTIKAGLFGNFTAQLRFISDFSIS---YEGFNITFSEYDLEPCD---DPGVPAFSRRI 1058
H A + + + + +++ Y GF + S D DP +P +
Sbjct: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC 661
Query: 1059 ----GFHFG-----------VGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVA 1103
G H G G ++ ++C GY L G + C+ G WS PRC
Sbjct: 662 QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN--WSPSAPRCEE 719
Query: 1104 ECGASVK-------GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGD 1156
C + G+ L++ + Y Y++ +A GI +
Sbjct: 720 TCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWFK---------- 768
Query: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLT------- 1209
K+ K P + G++ + +L N + DQGF L
Sbjct: 769 --KIPLCKVIHCHPPPVIVNGKHTGMMAEN-----FLYGNEVSYECDQGFYLLGEKKLQC 821
Query: 1210 -----------------YTSFDLVKCEDPGIPNYGYRIRD--EGHFTDTVVLYSCNPGYA 1250
S + +C +P + +GY++ + + +V CNPG+
Sbjct: 822 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFI 880
Query: 1251 MHGSNTLTCLSGDRRVWDKPLPSCI 1275
M+GS + C + + W +P+CI
Sbjct: 881 MNGSRVIRCHTDN--TWVPGVPTCI 903
Score = 43.5 bits (101), Expect = 0.004
Identities = 100/481 (20%), Positives = 171/481 (35%), Gaps = 79/481 (16%)
Query: 511 IGSPGFKAVYQEIEKGG-----CGDPGIPAYGKRT--GSSFLHGDTLTFECPAAFELVGE 563
+G+ G V+ + G CG P G+ + + G + + C F L+GE
Sbjct: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
Query: 564 RVITC----QQNNQWSGNKPSCVFSCFFNFTAS-------SGIILSPNYPEEYG------ 606
+ + C + + W P C + FN +S G + + P +G
Sbjct: 61 KSLLCITKDKVDGTWDKPAPKCEY---FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFA 117
Query: 607 -------NNMNCVWLIISEPG--SRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSG 657
N VW + +R+ + F +E L + +G +G+ +
Sbjct: 118 CKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLE--CPALPMIHNGHHTSENVGSIAP 175
Query: 658 NEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFL-L 716
+ SG+++ E + ++G+ ++ T + C G NG+ L +
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGK-WSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
Query: 717 GSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE---APC------GGHLTASS 767
G + +F CD+G+ + QG S C++ V W+ +P CE P G H+ S
Sbjct: 235 GVTANFFCDEGY-RLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSL 292
Query: 768 GVILPPGWPGYYKDSLHCEWIIEAKPGHS-IKITFDRFQTEVNYDTLEVRDGPASSSPLI 826
+ Y D E + G S ++ T D +T GPA L
Sbjct: 293 ANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGT-------WSGPAPRCELS 345
Query: 827 GEYHGTQAPQFL----ISTGNFMYLLFTTDNSRSSIGFLIH-YESVTLESDSCLDPGIPV 881
PQ L +S Y T GF + + + + +P PV
Sbjct: 346 TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPV 405
Query: 882 ------------NGH---RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPS 926
NG RH F +++ +SC+PGY L +E + C W +P
Sbjct: 406 CEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQ 465
Query: 927 C 927
C
Sbjct: 466 C 466
Score = 41.2 bits (95), Expect = 0.019
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 2088 CPDPPPFQNGYMIN---SDYSVGQSVSFECYP------GYILIGHPVLTCQHGINR--NW 2136
CP PPP NG I ++ S G V++ C P +ILIG L C + W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 2137 NYPFPRCD 2144
+ P PRC+
Sbjct: 336 SGPAPRCE 343
Score = 39.7 bits (91), Expect = 0.054
Identities = 52/230 (22%), Positives = 86/230 (37%), Gaps = 28/230 (12%)
Query: 1239 TVVLYSCNPGYAMHGSNTLTCLSGDR--RVWDKPLPSCIAECGGQIHAATSGRILSPGY- 1295
TV+ YSC+ + + G +L C++ D+ WDKP P C E + +++ I+ GY
Sbjct: 45 TVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC--EYFNK-YSSCPEPIVPGGYK 101
Query: 1296 ---PAPYDN----NLHCTWIIEADPGKTISLHF-IVFDTEMAHDILKVWDGPVDSDILLK 1347
PY + C + K++ ++ + V+ P++ L
Sbjct: 102 IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF--PLECPALPM 159
Query: 1348 EWSGSALPEDIHSTFNSLTLQFDSDF-----------FISKSGFSIQFSTSIAATCNDPG 1396
+G E++ S L++ + + +S +S T A C G
Sbjct: 160 IHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLG 219
Query: 1397 MPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
NG + G T F CD GY+LQG CV W P
Sbjct: 220 RFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
Score = 39.3 bits (90), Expect = 0.070
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query: 1740 TQCSSVPEPRYGRRIG---SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
T+C + PE ++G ++ S +S IV +CNPG+++ GS + C + W +
Sbjct: 845 TRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGV 899
Query: 1797 PSCV 1800
P+C+
Sbjct: 900 PTCI 903
Score = 39.3 bits (90), Expect = 0.070
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 160 RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
RF+ G I YSC GY+L G A+L C + +W PAP C+
Sbjct: 928 RFSPGMSILYSCDQGYLLVGEALLLCT----HEGTWSQPAPHCK 967
Score = 38.5 bits (88), Expect = 0.12
Identities = 56/259 (21%), Positives = 86/259 (33%), Gaps = 71/259 (27%)
Query: 2088 CPDPPPFQNGYMINSDY---SVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC- 2143
CP P NG+ + + + G SV++ C GY+L+G ++ C + W+ P C
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLS--SGKWSAVPPTCE 211
Query: 2144 DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
+A C NG + P PIL+ GV NF + +
Sbjct: 212 EARCKSLGRFPNGKVKEP------PILR-----------VGVTANFFCDEGYRL------ 248
Query: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPP 2263
GP + V +G T ++ C PP
Sbjct: 249 -QGPPSSR---CVIAGQGVAWTKMPVCEEIF------------------------CPSPP 280
Query: 2264 AVPQAEMLTED-DDFEIGDFVKYQCHP------GYTLVGTDILTCKLSSQL--QFEGSLP 2314
+ + + G V Y C P + L+G L C + SQ + G P
Sbjct: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
Query: 2315 TCE-----AQCPANEVRTG 2328
CE QCP ++ G
Sbjct: 341 RCELSTSAVQCPHPQILRG 359
Score = 38.1 bits (87), Expect = 0.16
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 7/65 (10%)
Query: 695 QNECHDPGIPINGR---RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSST 751
+ EC P +NG+ R RF G+S+ + C+ G+V G ESI C + VW+
Sbjct: 407 EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-GEESIQCTSEG---VWTPP 462
Query: 752 VPRCE 756
VP+C+
Sbjct: 463 VPQCK 467
Score = 36.2 bits (82), Expect = 0.60
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 877 PGIPV--NGHRHGGDFGIRS---TVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC-DAL 930
P +P+ NGH + G + +VT+SC+ GY L ++ + C + +W+ P+C +A
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEAR 214
Query: 931 CGGYIQGKSGTVLSP 945
C + +G V P
Sbjct: 215 CKSLGRFPNGKVKEP 229
Score = 33.5 bits (75), Expect = 3.9
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 1062 FGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
F G S+ +SC GY L G L C G WS P P C
Sbjct: 929 FSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHC 966
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 258 bits (659), Expect = 7e-68
Identities = 181/539 (33%), Positives = 269/539 (49%), Gaps = 36/539 (6%)
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNH-ECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
A C S EG + S ++P NN EC Y + G G+ L+ +S L +G+ L +
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
Query: 1162 DGKDSSSRPLGTFTKNELL---GLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKC 1218
G D P T N+ L G ++ S +N + + F T D FQL Y +F ++ C
Sbjct: 339 -GVDG---PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSC 393
Query: 1219 EDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAEC 1278
P P+ G + H + V + C+ GY + G+ LTC++ + W P C A C
Sbjct: 394 NFPRRPDSGDVTVMDLH-SGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPC 452
Query: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH--DILKVW 1336
GG +H AT GR+LSP YP + + C W IEA G+ + LH F+ + H D + V
Sbjct: 453 GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLH---FERLLLHDKDRMTVH 509
Query: 1337 DGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCND 1394
G + LL + + S E + S N++ ++F SD + S F+I+F C +
Sbjct: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
Query: 1395 PGMPQNG--TRYGDSREAGDTVTFQCDPGYQL-QGQAKITCVQLNNRFFWQPDPPTCIAA 1451
P + QNG T + G V F CDPG+ L QG A I C+ + + +W P C A
Sbjct: 570 PYI-QNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDP-YWNDTEPLCRAM 627
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
CGG L+ AGV+LSPN+P+PY G++C W++ V + I L + N+ S D L IY+G
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGL-----SGFAIEFKEKPR-EAC 1565
++ ++G Y G+ P+++ SS L + F SD + GL GF + + E R ++C
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPA-GLIFGKGQGFIMNYIEVSRNDSC 745
Query: 1566 FDPGNIMNG--TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
D I NG T T+ G+ ITYQCD GY I+ ++TC SW P C
Sbjct: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFC 800
Score = 213 bits (542), Expect = 3e-54
Identities = 156/533 (29%), Positives = 251/533 (47%), Gaps = 30/533 (5%)
Query: 1803 CSGNFTQRRGTILSPGYPE-PYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHD 1861
CS +F+ G I S YP P N L C + + V G G+++QV S N E+
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSV----NLSDGELLS 336
Query: 1862 GGDVTAPRLGSFSGTTVPA---LLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
V P L + T+ ++ S +N + ++F++ F L Y+ L+ C
Sbjct: 337 IRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNF 395
Query: 1919 PALP-SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGG 1977
P P S + + D + V F C GY LQG ++C+ + W+ P+C A CGG
Sbjct: 396 PRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGG 454
Query: 1978 TL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP 2035
+ +T+G V LSP +P + + C W I P G H+ F + D + + +G
Sbjct: 455 AVHNATIGRV-LSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQ 512
Query: 2036 YHTSPMIGQFSGTD-LP-AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPP 2093
+ S ++ T+ +P LLS + I F SD ++ F + ++A+E +C +P
Sbjct: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
Query: 2094 FQNGYMINSD--YSVGQSVSFECYPGYILIGHP-VLTCQHGINRNWNYPFPRCDAPCGYN 2150
QNG SD Y++G V F C PG+ L P ++ C + + WN P C A CG
Sbjct: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQN 2210
+++ G + SP +P+ Y +DCIW I V ++++ L + +D + ++DG +
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYDGDEVM 690
Query: 2211 SPQLGVFSGNTALETAYSSTNQVLLKFHSD-----FSNGGFFVLNF-HAFQLKKCQPPPA 2264
LG + GN+ + YSST + ++FHSD F G F++N+ + C P
Sbjct: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
Query: 2265 VPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
+ T + G + YQC PGY +VG+D LTC+ L + P CE
Sbjct: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQW--DLSWSSDPPFCE 801
Score = 211 bits (536), Expect = 1e-53
Identities = 195/737 (26%), Positives = 305/737 (41%), Gaps = 84/737 (11%)
Query: 385 SKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN-AHCVWVIT 443
S+ T + T ++ P C + P G I S +YP+ +N C + +T
Sbjct: 258 SQETTTSTIITTTVITTEQAPAL----CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVT 313
Query: 444 TTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWL 503
V +L + L G + L++ G G T +VL T +I S +N + +
Sbjct: 314 VYTGYGV-ELQVKSVNLSDG-ELLSI--RGVDGPTLTVLANQTLLVEGQVIRSPTNTISV 369
Query: 504 HLQS--DDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELV 561
+ ++ DD +G+ F+ YQ C P P G T G F C +EL
Sbjct: 370 YFRTFQDDGLGT--FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQ 426
Query: 562 GERVITCQQNNQ--WSGNKPSCVFSCFFNF-TASSGIILSPNYPEEYGNNMNCVWLIISE 618
G +++TC ++ WS +P C C A+ G +LSP+YPE + C+W I +
Sbjct: 427 GAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAP 486
Query: 619 PGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQS 677
G ++HL F + + + + VP + L S G+ +R+EF S
Sbjct: 487 EGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTS 546
Query: 678 DHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGD-RFLLGSSVSFHCDDGFVKTQGSES 736
D + FNI + F + C++P I D + +G+ V F CD G QG
Sbjct: 547 DQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAI 606
Query: 737 ITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHS 796
I CI + W+ T P C A CGG L+A +GV+L P WP Y + C W I G
Sbjct: 607 IECI-NVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV--GEE 663
Query: 797 IKITFD-RFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS- 854
+I D +F N D L + DG ++G+Y G PQ L S+ + + F +D +
Sbjct: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAG 723
Query: 855 ---RSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGI--RSTVTFSCDPGYTLSDD 909
GF+++Y V+ +DSC D NG + + + +T+ CDPGY +
Sbjct: 724 LIFGKGQGFIMNYIEVS-RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGS 782
Query: 910 EPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGV 969
+ L C+ + W+ P C+ + + CT EV H +
Sbjct: 783 DTLTCQWDLSWSSDPPFCEKI------------------------MYCTDPGEVDHSTRL 818
Query: 970 QMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFIS---D 1026
S+PV L G+ + +T G ++ L S
Sbjct: 819 -----------------------ISDPVL-LVGTTIQYTCNPGFVLEGSSLLTCYSRETG 854
Query: 1027 FSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFH--FGVGDSLTFSCFLGYRLEGATKL 1084
I SE L CD+PG+P +I + + G+SLTF C+ G+ L G +
Sbjct: 855 TPIWTSRLPHCVSEESL-ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTI 913
Query: 1085 TCLGGGRRVWSAPLPRC 1101
C+ G W+ PLP C
Sbjct: 914 RCILGQPSHWNGPLPVC 930
Score = 197 bits (502), Expect = 1e-49
Identities = 155/539 (28%), Positives = 240/539 (44%), Gaps = 34/539 (6%)
Query: 1624 APCGGQYTGSEGVVLSPNYP----HNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLA 1679
A C ++ EG + S +YP +N+ C Y++TV + V Q + +L
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLE---CTYNVTVYTGYGVELQVKSVNLSDGELL 335
Query: 1680 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
+ +L++ + G+ + T N I + F F YQA +
Sbjct: 336 SIRGVDGPTLTVLANQTLLVEGQVIRSPT-NTISVYFRTFQDDGLGTFQLHYQAFMLS-- 392
Query: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
C+ P G + +G + F C+ GY LQG+ L C + + W+ P C
Sbjct: 393 --CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC--INASKPHWSSQEPIC 448
Query: 1800 VVPCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLE 1858
PC G G +LSP YPE + CIW I EG + + D +
Sbjct: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMT 507
Query: 1859 IHDGG-DVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAAC 1916
+H G + +A S +VP L S N + + F SD + AA+ F++ ++ C
Sbjct: 508 VHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
Query: 1917 QEPALPSNSIKIGD-RYMVNDVLSFQCEPGYTL-QGRSHISCMPGTVRRWNYPSPLCIAT 1974
EP + + + D Y + ++ F C+PG++L QG + I C+ WN PLC A
Sbjct: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISL--PIGYGAHIQFLNFSTEANHDFLEIQ 2032
CGG LS + GV+LSP +P Y DC W+I + IQFLN S N D L I
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS---NSDILTIY 684
Query: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS----QNRQGFKLAY-QAYELQN 2087
+G ++GQ+ G P L S+T + I F+SD + QGF + Y + +
Sbjct: 685 DGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDS 744
Query: 2088 CPDPPPFQNGYMINSDYSV--GQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2144
C D P QNG+ S + G ++++C PGY ++G LTCQ + +W+ P C+
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL--SWSSDPPFCE 801
Score = 184 bits (467), Expect = 1e-45
Identities = 140/508 (27%), Positives = 234/508 (46%), Gaps = 21/508 (4%)
Query: 1288 GRILSPGYPA-PYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILL 1346
G I S YP P +N L CT+ + G + L V ++ L G VD L
Sbjct: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQ--VKSVNLSDGELLSIRG-VDGPTLT 346
Query: 1347 KEWSGSALPED--IHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRY 1404
+ + L E I S N++++ F + F + + + +CN P P +G
Sbjct: 347 VLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQ-AFMLSCNFPRRPDSGDVT 405
Query: 1405 GDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL-TGPAGVI 1463
+G F C GY+LQG +TC+ + W P C A CGG + G +
Sbjct: 406 VMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGRV 464
Query: 1464 LSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLI-GSY 1522
LSP+YP+ + C W ++ + L F+ + D + ++ G+ + S L+ S
Sbjct: 465 LSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDSL 523
Query: 1523 QGSQAP-ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTD- 1580
Q P E + S GN++ + F SD + S F I F+ + C++P I NG +D
Sbjct: 524 QTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSDP 582
Query: 1581 -FKLGSTITYQCDSGYKILD-PSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVL 1638
+ +G+ + + CD G+ + P+ I C+ D P W+ P C A CGG+ + GVVL
Sbjct: 583 TYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVVL 640
Query: 1639 SPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGS 1698
SPN+P Y G+ C++ I V +E +F + + +D+ ++DG +L G+
Sbjct: 641 SPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGN 700
Query: 1699 HSGETLPLATSNQILLRFSAKSG-ASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGS- 1756
+ L +T + + S +G +G F+ + + + CS +PE + G + S
Sbjct: 701 SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSH 760
Query: 1757 -EFSAGSIVRFECNPGYLLQGSTALHCQ 1783
E G+ + ++C+PGY + GS L CQ
Sbjct: 761 TELVRGARITYQCDPGYDIVGSDTLTCQ 788
Score = 183 bits (464), Expect = 3e-45
Identities = 172/671 (25%), Positives = 288/671 (42%), Gaps = 40/671 (5%)
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNN-LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
A C + S G I S +P NN L+CT+ +++ GYG +Q + + ++ + L I
Sbjct: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSI 337
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+ T ++ + + S T+ ++F + F+L YQA+ L +C P
Sbjct: 338 RGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCNFP 396
Query: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV 2151
+G + D G F C+ GY L G +LTC + +W+ P C APCG V
Sbjct: 397 RRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAV 456
Query: 2152 TSQN-GTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQN 2210
+ G + SP +P+ + CIW I P G ++++F L D + V G
Sbjct: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQTNK 515
Query: 2211 SPQL--GVFSGNTALETAYSSTNQVLLKFHSDFSNGGF-FVLNFHAFQLKKCQPPPAVPQ 2267
S L + + + E S N + ++F SD + F + F AF+ C P +
Sbjct: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQN 574
Query: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLV-GTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
T D + IG V++ C PG++L G I+ C + + P C A C
Sbjct: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE--L 632
Query: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQS 2386
+ +GV+LSP +P Y + C W I V I + + F + D L ++DG
Sbjct: 633 SAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQ-FLNLSNSDILTIYDGDEVMP 691
Query: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHA----TSKKGFKIRYAA----PYCSLTHP 2438
+L GN Q ++S + L +++ +D A +GF + Y CS
Sbjct: 692 HILGQYLGNSGPQKLYSS-TPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
Query: 2439 LKNG-GILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS-C 2496
++NG + T G+++ Y C PGY +VG TC+ + W S P C+ + C
Sbjct: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEKIMYC 806
Query: 2497 GIPESPGNGS--FTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG--LWSNKGKPPT 2552
P + + + + + + Y C+ GF LE S T +E G +W++ + P
Sbjct: 807 TDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS--RLPH 864
Query: 2553 C---KPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTW 2609
C + +AC + L E+ ++++ L G + C G+ L G +RC
Sbjct: 865 CVSEESLACDN--PGLPENG-YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS 921
Query: 2610 NIGDERPSCRV 2620
+ P C+V
Sbjct: 922 HWNGPLPVCKV 932
Score = 171 bits (433), Expect = 1e-41
Identities = 183/718 (25%), Positives = 293/718 (40%), Gaps = 96/718 (13%)
Query: 585 CFFNFTASSGIILSPNYPEEYGNN-MNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKD 643
C +F+ G I S +YP NN + C + + G + L ++ + L+++
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSIRG 339
Query: 644 DGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGI 703
+TVL + + S + + + F++ F + Y F C+ P
Sbjct: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
Query: 704 PINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHL 763
P +G G FHC G+ + QG++ +TCI WSS P C APCGG +
Sbjct: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
Query: 764 -TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASS 822
A+ G +L P +P S C W IEA G + + F+R + D + V G +
Sbjct: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
Query: 823 SPLIGEYHGTQAPQF--LISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIP 880
S L+ + T++ F L+S GN + + FT+D +R++ F I +E+ E C +P I
Sbjct: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEA--FEKGHCYEPYIQ 573
Query: 881 VNGHRHGGD--FGIRSTVTFSCDPGYTLSDDEPLVCE----RNHQWNHALPSCDALCGGY 934
NG+ D + I + V F+CDPG++L + P + E R+ WN P C A+CGG
Sbjct: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
Query: 935 IQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFS 994
+ +G VLSP +P+ Y +C W I V K + + +L +S +L DG
Sbjct: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSD--ILTIYDGD-- 687
Query: 995 EPVARLTGSVLPHTIKAGLFGNFTAQLRFIS--DFSISY------------EGFNITFSE 1040
V+PH + L GN Q + S D +I + +GF + + E
Sbjct: 688 --------EVMPHILGQYL-GNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
Query: 1041 YDL-EPCDDPGVPAFSRRIGFHFGV--GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAP 1097
+ C D + H + G +T+ C GY + G+ LTC WS+
Sbjct: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
Query: 1098 LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT 1157
P C ++ P D++ I G I + EG +
Sbjct: 797 PPFCEK------------IMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSS 844
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
L SR GT I S H S + +
Sbjct: 845 LLT-----CYSRETGT--------PIWTSRLPHC-------------------VSEESLA 872
Query: 1218 CEDPGIPNYGYRIRDEG-HFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
C++PG+P GY+I + + + + C G+ + G T+ C+ G W+ PLP C
Sbjct: 873 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 158 bits (399), Expect = 1e-37
Identities = 171/705 (24%), Positives = 279/705 (39%), Gaps = 81/705 (11%)
Query: 761 GHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPA 820
G++ +S +LP + L C + + G+ +++ + + L +R
Sbjct: 290 GYIDSSDYPLLP------LNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDG 342
Query: 821 SSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIP 880
+ ++ Q + S N + + F T F +HY++ L SC P P
Sbjct: 343 PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRP 399
Query: 881 VNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVC--ERNHQWNHALPSCDALCGGYIQGK 938
+G D F C GY L + L C W+ P C A CGG +
Sbjct: 400 DSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNA 459
Query: 939 S-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPV 997
+ G VLSP +P+ S C WTIE G+ + + F L HD +T +
Sbjct: 460 TIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKS 516
Query: 998 ARLTGSVLPHTIK-AGLF--GNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAF 1054
A L S+ ++ GL GN T ++ F SD + + FNI F ++ C +P +
Sbjct: 517 ALLYDSLQTESVPFEGLLSEGN-TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNG 575
Query: 1055 SRRIGFH-FGVGDSLTFSCFLGYRLE-GATKLTCLGGGRRVWSAPLPRCVAECGASVKGN 1112
+ + +G + F+C G+ LE G + C+ W+ P C A CG +
Sbjct: 576 NFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAV 635
Query: 1113 EGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLG 1172
G +LSPN+P Y +CI+KI K I L + L D L +YDG + LG
Sbjct: 636 AGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILG 695
Query: 1173 TFTKNELLGLILNSTSNHLWLEFNTNGSDT----DQGFQLTYTSFDLV-KCED-PGIPNY 1226
+ N + +ST + L ++F+++ + QGF + Y C D P I N
Sbjct: 696 QYLGNSGPQKLYSSTPD-LTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQN- 753
Query: 1227 GYRIRDEGHFTDTV-VLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAA 1285
G++ + Y C+PGY + GS+TLTC WD S C
Sbjct: 754 GWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQ------WDLSWSSDPPFC------- 800
Query: 1286 TSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDIL 1345
+ ++CT DPG E+ H + D +
Sbjct: 801 --------------EKIMYCT-----DPG------------EVDHSTRLISDPVLLVGTT 829
Query: 1346 LKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTR-- 1403
++ + S + + + + S+ + S+A C++PG+P+NG +
Sbjct: 830 IQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVS-EESLA--CDNPGLPENGYQIL 886
Query: 1404 YGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Y G+++TF C G++L G+ I C+ L W P C
Sbjct: 887 YKRLYLPGESLTFMCYEGFELMGEVTIRCI-LGQPSHWNGPLPVC 930
Score = 149 bits (375), Expect = 6e-35
Identities = 177/746 (23%), Positives = 292/746 (39%), Gaps = 112/746 (15%)
Query: 203 RAEGACGGTLRGTSSSISSPHFPSEYENN-ADCTWTILAEPGDTIALVFTDFQLEEGYDF 261
+A C + I S +P NN +CT+ + G + L L +G +
Sbjct: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
Query: 262 LEISGTEAPSIWLTG---MNLPSPVISSK-NWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
L I G + P++ + + + VI S N + ++F + + F +Q
Sbjct: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
Query: 318 KSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCE 377
+LS C P P++G D G F C
Sbjct: 389 -----------------FMLS----------CNFPRRPDSGDVTVMDLHSGGV-AHFHCH 420
Query: 378 DNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAH 437
Y LQG+K +TC + + WS PIC A G+ G + SP+YP +
Sbjct: 421 LGYELQGAKMLTC--INASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQF 478
Query: 438 CVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVP-DLIVS 496
C+W I + K + L FE L D +TV +G+ + + L SVP + ++S
Sbjct: 479 CIWTIEAPEGQK-LHLHFERL-LLHDKDRMTV-HSGQTNKSALLYDSLQTESVPFEGLLS 535
Query: 497 MSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGS-SFLHGDTLTFECP 555
N + + SD + + F ++ EKG C +P I T ++ G + F C
Sbjct: 536 EGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCD 595
Query: 556 AAFEL-VGERVITC--QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCV 612
L G +I C ++ W+ +P C C +A +G++LSPN+PE Y +C+
Sbjct: 596 PGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCI 655
Query: 613 WLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVR 672
W I RI L ++ D L + D +LG + GN P +L SS +
Sbjct: 656 WKIHVGEEKRIFLDIQFLNLS-NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLT 714
Query: 673 LEFQSDHS----TTGRGFNITYTTFGQNE-CHDPGIPINGRRFGD--RFLLGSSVSFHCD 725
++F SD + G+GF + Y +N+ C D NG + + G+ +++ CD
Sbjct: 715 IQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCD 774
Query: 726 DGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHC 785
G+ GS+++TC ++ WSS P CE
Sbjct: 775 PGY-DIVGSDTLTC---QWDLSWSSDPPFCE----------------------------- 801
Query: 786 EWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFM 845
KI + EV++ T + D P +Y T P F++ + +
Sbjct: 802 ------------KIMYCTDPGEVDHSTRLISD-PVLLVGTTIQY--TCNPGFVLEGSSLL 846
Query: 846 YLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPG 903
+ L H V+ ES +C +PG+P NG++ + + ++TF C G
Sbjct: 847 TCYSRETGTPIWTSRLPH--CVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEG 904
Query: 904 YTLSDDEPLVC--ERNHQWNHALPSC 927
+ L + + C + WN LP C
Sbjct: 905 FELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 145 bits (366), Expect = 7e-34
Identities = 172/696 (24%), Positives = 277/696 (39%), Gaps = 88/696 (12%)
Query: 2145 APCGYNVTSQNGTIYSPGFPDEYPILK-----DCIWLITVPPGHGVYINFTLLQTEAVND 2199
A C + ++ G I S +YP+L +C + +TV G+GV LQ ++VN
Sbjct: 279 ALCSVSFSNPEGYIDS----SDYPLLPLNNFLECTYNVTVYTGYGVE-----LQVKSVN- 328
Query: 2200 YIAVWDGP-----DQNSPQLGVFSGNTAL---ETAYSSTNQVLLKFHSDFSNG-GFFVLN 2250
+ DG + P L V + T L + S TN + + F + +G G F L+
Sbjct: 329 ---LSDGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLH 385
Query: 2251 FHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFE 2310
+ AF L C P ++ D G + CH GY L G +LTC +S+ +
Sbjct: 386 YQAFMLS-CNFPRRPDSGDVTVMD--LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWS 442
Query: 2311 GSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
P C A C V + G +LSP YP N SQ C W+I+ + + +
Sbjct: 443 SQEPICSAPC-GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH 501
Query: 2371 KQFDALEVFDGSSGQSPLLV-VLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
+ D + V G + +S LL L S N + + +++D A + F IR+
Sbjct: 502 DK-DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE 560
Query: 2430 A---PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMV-GHSNATCR--RNPLGMYQ 2483
A +C + + +G+ V + C PG+ + G + C R+P
Sbjct: 561 AFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY---- 616
Query: 2484 WDSLTPLCQAVSCGIPESPGNGSFTGN---EFTLDSKVVYECHEGF--KLESSQQATAVC 2538
W+ PLC+A+ G + + N + +++ H G ++ Q +
Sbjct: 617 WNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS 676
Query: 2539 QEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPG----YY 2594
D L G ++ H++ + + S G Q L S +P ++
Sbjct: 677 NSDILTIYDGD--------------EVMPHILGQYLGNS----GPQKLYSSTPDLTIQFH 718
Query: 2595 LEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT--VYGATAIFTCNTG 2652
+ L+ + G I + R SC L NG K + T V GA + C+ G
Sbjct: 719 SDPAGLIFGKGQGF--IMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
Query: 2653 YTLVGSHVRECLANGLWSGSETRC-LAGHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNP 2709
Y +VGS C + WS C +C P + + IS T+ Y CNP
Sbjct: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNP 836
Query: 2710 GFRLVGTSVRICLQDHK----WSGQTPVCV---PITCGHPGNPAHGF--TNGSEFNLNDV 2760
GF L G+S+ C W+ + P CV + C +PG P +G+ + +
Sbjct: 837 GFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGES 896
Query: 2761 VNFTCNTGYLLQGVSRAQC--RSNGQWSSPLPTCRV 2794
+ F C G+ L G +C W+ PLP C+V
Sbjct: 897 LTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
Score = 136 bits (343), Expect = 3e-31
Identities = 148/570 (25%), Positives = 231/570 (40%), Gaps = 70/570 (12%)
Query: 32 CGGLVQGPNGTIESPGFPH-GYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSV-- 88
C P G I+S +P N+ CT+ + ++L + L D ++LS+
Sbjct: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRG 339
Query: 89 YDGQPQQ--GNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
DG N + + G I S + ++++F T F G L+ +C
Sbjct: 340 VDGPTLTVLANQTLLVEG----QVIRSPTNTISVYFRT-FQDDGLGTFQLHYQAFMLSCN 394
Query: 147 NPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEG 206
P G + + G + C GY L+G +LTCI + + W P C A
Sbjct: 395 FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINA--SKPHWSSQEPICSAP- 451
Query: 207 ACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEIS 265
CGG + T + SP +P + C WTI A G + L F L + S
Sbjct: 452 -CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
Query: 266 G-TEAPSIWLTGMNLPSP----VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
G T ++ + S ++S N +R+ FTSD FN +F+
Sbjct: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE---------- 560
Query: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFS-RVGANVQFSCEDN 379
A C +P I +NG SD + +G V+F+C+
Sbjct: 561 ----------------------AFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
Query: 380 YVL-QGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHC 438
+ L QG I C V + W+D P+CRA CG L +GV+ SPN+P Y + C
Sbjct: 598 HSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVVLSPNWPEPYVEGEDC 654
Query: 439 VWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMS 498
+W I + +K I L + L D LT+ D +V +L G+S P + S +
Sbjct: 655 IWKIHVGE-EKRIFLDIQFLNLSNS-DILTIYDGDEV--MPHILGQYLGNSGPQKLYSST 710
Query: 499 NQMWLHLQSDDS---IG-SPGFKAVYQEIEKG-GCGD-PGIPAYGKRTG-SSFLHGDTLT 551
+ + SD + G GF Y E+ + C D P I K T + + G +T
Sbjct: 711 PDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARIT 770
Query: 552 FECPAAFELVGERVITCQQNNQWSGNKPSC 581
++C +++VG +TCQ + WS + P C
Sbjct: 771 YQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 106 bits (264), Expect = 5e-22
Identities = 112/429 (26%), Positives = 173/429 (40%), Gaps = 68/429 (15%)
Query: 32 CGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYD 90
CGG V G + SP +P C W I E ++ L F L D D ++V+
Sbjct: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHS 510
Query: 91 GQPQQGNLKV-RLSGFQLP-SSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
GQ + L L +P ++S G+ + + FT+D A +A F +E C P
Sbjct: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
Query: 149 GEILKG--VLHGTRFNIGDKIRYSCLPGYILE-GHAILTCIVSPGNGASWDFPAPFCRAE 205
I G +NIG + ++C PG+ LE G AI+ CI W+ P CRA
Sbjct: 571 -YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV--RDPYWNDTEPLCRA- 626
Query: 206 GACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEIS 265
CGG L + + SP++P Y DC W I G+ +F D Q FL +S
Sbjct: 627 -MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKI--HVGEE-KRIFLDIQ------FLNLS 676
Query: 266 GTEAPSIW------------LTGMNLPSPVISSKNWLRLHFTSDSN----HRRKGFNAQF 309
++ +I+ G + P + SS L + F SD + +GF +
Sbjct: 677 NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNY 736
Query: 310 -------------QVKKAIELKS-----RGVKML----PSKDGSHKNSVLSQGGVALVSD 347
+++ + S RG ++ P D +++ Q ++ SD
Sbjct: 737 IEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSD 796
Query: 348 --------MCPDPGIPENGRRAGSD-FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLA 398
C DPG ++ R SD VG +Q++C +VL+GS +TC
Sbjct: 797 PPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
Query: 399 AWSDHRPIC 407
W+ P C
Sbjct: 857 IWTSRLPHC 865
Score = 90.1 bits (222), Expect = 3e-17
Identities = 130/617 (21%), Positives = 210/617 (34%), Gaps = 121/617 (19%)
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQC--RSNGQWSSPLPTCR- 2793
++C P P G + + V +F C+ GY LQG C S WSS P C
Sbjct: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
Query: 2794 ----------VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCM 2843
+ P + EN +G Q + E H LL +
Sbjct: 451 PCGGAVHNATIGRVLSPSYPENT--NGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
Query: 2844 ANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQED 2903
+G ++S L S VP +L+ G + ++ + + E
Sbjct: 509 HSGQTNKSA--LLYDSLQTESVPFEGLLSE-----GNTIRIEFTSDQARAASTFNIRFE- 560
Query: 2904 SHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-FKTKSLLRFSCEMGHQLRGSPERTCL 2962
G C +P D + +++ F+C+ GH L P
Sbjct: 561 -----------AFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIEC 609
Query: 2963 LNGS---WSGLQPVCEAVSCGNPGTPTNGMIVSSDG------------------------ 2995
+N W+ +P+C A+ CG + G+++S +
Sbjct: 610 INVRDPYWNDTEPLCRAM-CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFL 668
Query: 2996 ----ILFSSSVIYACWEGYKTSGLMTRHCTANG---TWTGTAPDCTIISCGDPGTLANGI 3048
+ S+S I ++G + + N + PD TI DP G+
Sbjct: 669 DIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPA----GL 724
Query: 3049 QFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNG- 3107
FG G++M + V + C P +QNG
Sbjct: 725 IFGK------------GQGFIMNYIE-----------------VSRNDSCSDLPEIQNGW 755
Query: 3108 -TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV-FCGDPG-IPAE 3164
T ++ G+ I+Y C GY + S L+C+ W + P C + +C DPG +
Sbjct: 756 KTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHS 815
Query: 3165 GRL-SGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT----WSGIQPTCIDPAHNTCPD 3219
RL S + + + C F+L GSS C + T W+ P C+ C +
Sbjct: 816 TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN 875
Query: 3220 PGTPHFGIQ-NSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLT--WSG------IQTE 3270
PG P G Q R Y G ++ F C +G+ + G T C+ W+G + +
Sbjct: 876 PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQD 935
Query: 3271 CIPHACRQPETPAHADV 3287
HA E A +
Sbjct: 936 SFEHALEVAEAAAETSL 952
Score = 82.4 bits (202), Expect = 7e-15
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT-CGHPGNPAHG--FTNGSEFNLND 2759
+ YQC+PG+ +VG+ C D WS P C I C PG H + +
Sbjct: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
Query: 2760 VVNFTCNTGYLLQGVSRAQCRSNGQ----WSSPLPTC---RVVNCSDPGFVENAIRHGQQ 2812
+ +TCN G++L+G S C S W+S LP C + C +PG EN Q
Sbjct: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGY---QI 885
Query: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRSLPKC 2855
+ + G S+ + C +GF L+G + C+ W+ LP C
Sbjct: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 76.6 bits (187), Expect = 4e-13
Identities = 95/374 (25%), Positives = 137/374 (36%), Gaps = 88/374 (23%)
Query: 3038 CGDPGTLANGIQFGTDFTFN--KTVSYQCNPGYVMEAVTSATIRC--TKDGRWNPSKPVC 3093
C +P + NG +D T+N V + C+PG+ +E A I C +D WN ++P+C
Sbjct: 567 CYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQ-GPAIIECINVRDPYWNDTEPLC 624
Query: 3094 KA------------VLCPQPPPVQNGTVEGSDFRWGSSIS-----YSCMDGYQLSHSAIL 3136
+A VL P P VEG D W + + + LS+S IL
Sbjct: 625 RAMCGGELSAVAGVVLSPNWPEPY---VEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDIL 681
Query: 3137 SC-----------------EGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTY----- 3174
+ G P F DP G+ G Y
Sbjct: 682 TIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSR 741
Query: 3175 ------------------------KSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCI 3210
+ + +QC + +VGS CQ D +WS P C
Sbjct: 742 NDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
Query: 3211 DPAHNTCPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQT 3269
+ C DPG H S VG+T+ + C G+ ++GS+ TC + T + I T
Sbjct: 802 KIMY--CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWT 859
Query: 3270 ECIPH-------ACRQPETPAHAD---VRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCK 3319
+PH AC P P + + + LP G +L + C+ GF L G R
Sbjct: 860 SRLPHCVSEESLACDNPGLPENGYQILYKRLYLP--GESLTFMCYEGFELMGEVTIRCIL 917
Query: 3320 AD-MKWTGKSPVCK 3332
W G PVCK
Sbjct: 918 GQPSHWNGPLPVCK 931
Score = 66.2 bits (160), Expect = 5e-10
Identities = 69/303 (22%), Positives = 103/303 (33%), Gaps = 94/303 (31%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYDG 91
CGG + G + SP +P Y +C W I GE RI L L DIL++YDG
Sbjct: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
Query: 92 QPQQGNLKVRLSGFQLPSSIVSTGSILTL------------------------------- 120
++ + G P + S+ LT+
Sbjct: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
Query: 121 --------WFTTDFAVSAQGFKALYEVLPSHT---------------------------C 145
W TT +G + Y+ P + C
Sbjct: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYC 806
Query: 146 GNPGEILKGVLHGTRFN------IGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
+PGE V H TR +G I+Y+C PG++LEG ++LTC W
Sbjct: 807 TDPGE----VDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 862
Query: 200 PFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGY 259
P C +E S + +P P EN + L PG+++ F EG+
Sbjct: 863 PHCVSE---------ESLACDNPGLP---ENGYQILYKRLYLPGESLT-----FMCYEGF 905
Query: 260 DFL 262
+ +
Sbjct: 906 ELM 908
Score = 46.6 bits (109), Expect = 4e-04
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 1915 ACQEPALPSNSIKIGDR--YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
AC P LP N +I + Y+ + L+F C G+ L G I C+ G WN P P+C
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 46.2 bits (108), Expect = 6e-04
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 1565 CFDPGNIMNGTRVGTD--FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
C DPG + + TR+ +D +G+TI Y C+ G+ + S +TC G P W LP C
Sbjct: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Score = 36.2 bits (82), Expect = 0.60
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 142 SHTCGNPGEILKG--VLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
S C NPG G +L+ + G+ + + C G+ L G + CI+ G + W+ P
Sbjct: 870 SLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL--GQPSHWNGPL 927
Query: 200 PFCR 203
P C+
Sbjct: 928 PVCK 931
Score = 35.8 bits (81), Expect = 0.78
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 1392 CNDPGMPQNGTRYGDSRE--AGDTVTFQCDPGYQLQGQAKITCVQLNNRF-FWQPDPPTC 1448
C DPG + TR G T+ + C+PG+ L+G + +TC W P C
Sbjct: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
Query: 1449 IA 1450
++
Sbjct: 866 VS 867
Score = 34.3 bits (77), Expect = 2.3
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 1564 ACFDPGNIMNGTRVGTD--FKLGSTITYQCDSGYKILDPSSITCVIGADGKPS-WDQVLP 1620
AC +PG NG ++ + G ++T+ C G++++ +I C++ G+PS W+ LP
Sbjct: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL---GQPSHWNGPLP 928
Query: 1621 SC 1622
C
Sbjct: 929 VC 930
Score = 33.9 bits (76), Expect = 3.0
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 349 CPDPGIPENGRRAGSDFSRV---GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRP 405
C +PG+PENG + + R+ G ++ F C + + L G +I C + + W+ P
Sbjct: 873 CDNPGLPENGYQI--LYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLP 928
Query: 406 ICR 408
+C+
Sbjct: 929 VCK 931
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 251 bits (642), Expect = 7e-66
Identities = 169/607 (27%), Positives = 253/607 (41%), Gaps = 72/607 (11%)
Query: 2588 SCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI-SCGSLSFPPN-----GNKIGTLTVY 2641
SC PG+Y P C + CG L P + + +G + +
Sbjct: 184 SCYPGFY--------------------GPECEYVRECGELELPQHVLMNCSHPLGNFS-F 222
Query: 2642 GATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHI----SGDGF 2697
+ F C GY + G ECLA+G+W+ +CLA C G++ S F
Sbjct: 223 NSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAF 282
Query: 2698 SYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNG----S 2753
++ + + C GF LVG V C W+ PVC + C H P+ G + +
Sbjct: 283 QHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLT 342
Query: 2754 EFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQN 2813
F F C GY ++G+ +C +G WS+PLPTC ++C +E+ + HG +
Sbjct: 343 AFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEP---LESPV-HGSMD 398
Query: 2814 FPES---FEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAV 2870
S F+Y + + C +GF L G+ + C G W P C A+ C VP A
Sbjct: 399 CSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEAR 458
Query: 2871 LTGE----LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTG--NNPGFCGDP 2924
+ F Y +V ++C L+G C +W+ P C P
Sbjct: 459 VNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQN 518
Query: 2925 GTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGT 2984
GT LG KS +F C+ G+ L G C +G W+ P+CEA+ C
Sbjct: 519 GTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFA 577
Query: 2985 PTNGMIVSSD---GILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCT-IISCGD 3040
P G + SD S+ ++C G+K G CT +G W+ T P C I S
Sbjct: 578 PEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPT 637
Query: 3041 PG-------TLANGIQF-----GTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNP 3088
PG T G + GT F FN T + CN G+ + + +T+ C G+W
Sbjct: 638 PGVQCPALTTPGQGTMYCRHHPGT-FGFNTTCYFGCNAGFTL--IGDSTLSCRPSGQWTA 694
Query: 3089 SKPVCKAVLCPQ----PPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVW 3144
P C+AV C + P N + +F +GS S+ C++G L+ SA +C+ G W
Sbjct: 695 VTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHW 754
Query: 3145 KGEIPQC 3151
+P C
Sbjct: 755 STTVPTC 761
Score = 231 bits (590), Expect = 7e-60
Identities = 150/570 (26%), Positives = 236/570 (41%), Gaps = 44/570 (7%)
Query: 2562 EAQLSEHVIWRLVSGSLN-EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRV 2620
E +L +HV+ N + +Q C+ GY + G L C A+G W ++ P C
Sbjct: 202 ELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT--NKPPQCLA 259
Query: 2621 ISCGSLSFPPNGNKI----GTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC 2676
C L P GN + ++ F+C G+ LVG V +C A+G+W+ C
Sbjct: 260 AQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Query: 2677 LAGHCGSPDPIVNGHISG----DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2732
A C + G + F+Y + ++C PG+R+ G + C+ WS P
Sbjct: 320 KAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 379
Query: 2733 VCVPITCGHPGNPAHGFTNGS----EFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSP 2788
C I+C +P HG + S F + +F C G++L+G +C + GQW++P
Sbjct: 380 TCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAP 439
Query: 2789 LPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLW 2848
P C+ + C D V N R + +F Y + C +G L+G+S L C+A G W
Sbjct: 440 APVCQALQCQDLP-VPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNW 498
Query: 2849 DRSLPKCLAISCGHPGVPANAVLTG----ELFTYGAVVHYSCRGSESLIGNDTRVCQEDS 2904
+ P+C AI C P N +T +Y + + C SL G + C
Sbjct: 499 NSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSG 558
Query: 2905 HWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD----FKTKSLLRFSCEMGHQLRGSPERT 2960
W+ + P C C + P GS D F S FSC+ G +L G
Sbjct: 559 RWTDSPPMCEAIK---CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVE 615
Query: 2961 CLLNGSWSGLQPVCEAV-SCGNPGTPTNGMIVSSDGIL----------FSSSVIYACWEG 3009
C +G WS P C+ + S PG + G + F+++ + C G
Sbjct: 616 CTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAG 675
Query: 3010 YKTSGLMTRHCTANGTWTGTAPDCTIISCGD----PGTLANGIQFGTDFTFNKTVSYQCN 3065
+ G T C +G WT P C + C + N +F++ S+ C
Sbjct: 676 FTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCL 735
Query: 3066 PGYVMEAVTSATIRCTKDGRWNPSKPVCKA 3095
G ++ SA C ++G W+ + P C+A
Sbjct: 736 EGQLLNG--SAQTACQENGHWSTTVPTCQA 763
Score = 207 bits (526), Expect = 2e-52
Identities = 163/608 (26%), Positives = 242/608 (39%), Gaps = 69/608 (11%)
Query: 2436 THPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
+HPL N S+ + C GY++ G S C + + W + P C A
Sbjct: 214 SHPLGNFSF--------NSQCSFHCTDGYQVNGPSKLECLASGI----WTNKPPQCLAAQ 261
Query: 2496 CGIPESPGNGSFT----GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPP 2551
C + P G+ T F S + C EGF L + C G+W+ P
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPE--VVQCTASGVWT--APAP 317
Query: 2552 TCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNI 2611
CK V C +EA SE + + + YG+ C PGY + G +LRC +G W+
Sbjct: 318 VCKAVQCQHLEAP-SEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSA 376
Query: 2612 GDERPSCRVISCGSLSFPPNGNKIGTLTV----YGATAIFTCNTGYTLVGSHVRECLANG 2667
P+C ISC L P +G+ + ++ Y F C G+ L G+ + C G
Sbjct: 377 --PLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLG 434
Query: 2668 LWSGSETRCLAGHCGS-PDP---IVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQ 2723
W+ C A C P P VN F Y+ + CN G LVG SV CL
Sbjct: 435 QWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLA 494
Query: 2724 DHKWSGQTPVCVPITCGHPGNPAHGFTN-----GSEFNLNDVVNFTCNTGYLLQGVSRAQ 2778
W+ P C I C +P +G GS + F C+ GY L G R
Sbjct: 495 TGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLD 553
Query: 2779 CRSNGQWSSPLPTCRVVNC-----SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFY 2833
C +G+W+ P C + C + G ++ + G+ F G + + C GF
Sbjct: 554 CTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGE------FNVGSTCHFSCDNGFK 607
Query: 2834 LLGSSALTCMANGLWDRSLPKCLAI-SCGHPGVPANAVLT-GE----------LFTYGAV 2881
L G + + C +G W + P C I S PGV A+ T G+ F +
Sbjct: 608 LEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTT 667
Query: 2882 VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGD----PGTPAHGSRLGDDF 2937
++ C +LIG+ T C+ W+ P C C + + S L +F
Sbjct: 668 CYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVK---CSELHVNKPIAMNCSNLWGNF 724
Query: 2938 KTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEA--VSCGNPGTPTNGMIVSSDG 2995
S+ F C G L GS + C NG WS P C+A ++ T G + S+ G
Sbjct: 725 SYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIG 784
Query: 2996 ILFSSSVI 3003
++ +++
Sbjct: 785 LIMGGTLL 792
Score = 206 bits (525), Expect = 3e-52
Identities = 157/626 (25%), Positives = 250/626 (39%), Gaps = 65/626 (10%)
Query: 2757 LNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPE 2816
L + N+TC+ G R G+ LP ++NCS P
Sbjct: 175 LETIGNYTCSCYPGFYGPECEYVRECGELE--LPQHVLMNCSHP--------------LG 218
Query: 2817 SFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT---- 2872
+F + +HC G+ + G S L C+A+G+W P+CLA C +P +T
Sbjct: 219 NFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHS 278
Query: 2873 GELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS- 2931
+ F + + +SC +L+G + C W+ P C C P+ G+
Sbjct: 279 AKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQ---CQHLEAPSEGTM 335
Query: 2932 ---RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNG 2988
F S +F C+ G+++RG C+ +G WS P CEA+SC +P +G
Sbjct: 336 DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHG 395
Query: 2989 MIVSSDGI---LFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGD----- 3040
+ S + + ++ + C EG+ G C G WT AP C + C D
Sbjct: 396 SMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPN 455
Query: 3041 PGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQ 3100
+ FG F + S+ CN G ++ V ++ ++C G WN P C+A+ C
Sbjct: 456 EARVNCSHPFGA-FRYQSVCSFTCNEGLLL--VGASVLQCLATGNWNSVPPECQAIPCTP 512
Query: 3101 PPPVQNGTVE-----GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVF 3155
QNGT+ GS + S+ + C +GY LS L C G W P C +
Sbjct: 513 LLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIK 571
Query: 3156 CGDPGIPAEGRL----SGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCID 3211
C + P +G L + F S F C + F L G + C G WS PTC
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKG 631
Query: 3212 PAHNTCPDPGTPHFGIQNSSRG----------YEVGSTVFFRCRKGYHIQGSTTRTCLAN 3261
A + P PG + +G + +T +F C G+ + G +T +C +
Sbjct: 632 IA--SLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPS 689
Query: 3262 LTWSGIQTECIPHACRQPETPAHADVRAIDL---PTFGYTLVYTCHPGFFLAGGSEHRTC 3318
W+ + C C + + +L ++G + C G L GS C
Sbjct: 690 GQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLL-NGSAQTAC 748
Query: 3319 KADMKWTGKSPVCKSKGVREVNETVT 3344
+ + W+ P C++ G + E +T
Sbjct: 749 QENGHWSTTVPTCQA-GPLTIQEALT 773
Score = 150 bits (378), Expect = 3e-35
Identities = 106/415 (25%), Positives = 163/415 (39%), Gaps = 25/415 (6%)
Query: 2939 TKSLLRFSC-EMGHQLRGSPERTCLLNGSWSGLQPVCEAV-SCGNPGTPTNGMIVSSDGI 2996
T S SC + G L TC + G P CE V CG P + ++ S +
Sbjct: 160 TASCQDMSCSKQGECLETIGNYTCSCYPGFYG--PECEYVRECGELELPQHVLMNCSHPL 217
Query: 2997 ---LFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANG----IQ 3049
F+S + C +GY+ +G C A+G WT P C C G +
Sbjct: 218 GNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLH 277
Query: 3050 FGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTV 3109
F + S+ C G+ + V ++CT G W PVCKAV C GT+
Sbjct: 278 SAKAFQHQSSCSFSCEEGFAL--VGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTM 335
Query: 3110 EG----SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEG 3165
+ + F +GSS + C GY++ +L C G W +P C + C P G
Sbjct: 336 DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHG 395
Query: 3166 RL----SGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPG 3221
+ S ++F Y + F+C F+L G+ C G W+ P C P P
Sbjct: 396 SMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPN 455
Query: 3222 TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACR---Q 3278
+ + S F C +G + G++ CLA W+ + EC C
Sbjct: 456 EARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLS 515
Query: 3279 PETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKS 3333
P+ V+ + ++ T + C G+ L+ G E C +WT P+C++
Sbjct: 516 PQNGTMTCVQPLGSSSYKSTCQFICDEGYSLS-GPERLDCTRSGRWTDSPPMCEA 569
Score = 57.0 bits (136), Expect = 3e-07
Identities = 101/451 (22%), Positives = 151/451 (33%), Gaps = 101/451 (22%)
Query: 718 SSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWP- 776
SS SF C++GF G E + C VW++ P C+A HL A S + P
Sbjct: 286 SSCSFSCEEGFALV-GPEVVQCTASG---VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPL 341
Query: 777 GYYKDSLHCEWIIEAKPGHSIK-----ITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHG 831
+ C++ E +PG+ ++ D T E S PL HG
Sbjct: 342 TAFAYGSSCKF--ECQPGYRVRGLDMLRCIDSGHWSAPLPTCEA----ISCEPLESPVHG 395
Query: 832 TQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVT--------------LESDSCLDP 877
+ S F Y T + R + GF++ + ++ C D
Sbjct: 396 SM--DCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 451
Query: 878 GIP----VNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CG 932
+P VN G F +S +F+C+ G L L C WN P C A+ C
Sbjct: 452 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 511
Query: 933 GYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGV-QMIFHTFHLESSHDYLLITEDG 991
+ ++GT + C + S K Q I + S + L T G
Sbjct: 512 PLLSPQNGT-------------MTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSG 558
Query: 992 SFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGV 1051
+++ P LF L D S + FN+
Sbjct: 559 RWTDSPPMCEAIKCPE-----LFAPEQGSL----DCSDTRGEFNV--------------- 594
Query: 1052 PAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV--------- 1102
G + FSC G++LEG + C GR WSA P C
Sbjct: 595 -------------GSTCHFSCDNGFKLEGPNNVECTTSGR--WSATPPTCKGIASLPTPG 639
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIY 1133
+C A +GT+ + P + N C +
Sbjct: 640 VQCPALTTPGQGTMYCRHHPGTFGFNTTCYF 670
Score = 55.1 bits (131), Expect = 1e-06
Identities = 100/447 (22%), Positives = 146/447 (32%), Gaps = 81/447 (18%)
Query: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA-PCGGQYTGSEGVVLS 1639
F+ S+ ++ C+ G+ ++ P + C W P C A C SEG +
Sbjct: 282 FQHQSSCSFSCEEGFALVGPEVVQCTASG----VWTAPAPVCKAVQCQHLEAPSEGTMDC 337
Query: 1640 PNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLL------- 1692
+ + G C + Q Y L D+ D H A L
Sbjct: 338 VHPLTAFAYGSSCKFEC----------QPGYRVRGL-DMLRCIDSGHWSAPLPTCEAISC 386
Query: 1693 ----SSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVY--------QAVPRTSDT 1740
S + GS A F G RG V P
Sbjct: 387 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 446
Query: 1741 QCSSVPEPRYGRRIGSE----FSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
QC +P P R S F S+ F CN G LL G++ L C + N WN
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGN----WNSVP 502
Query: 1797 PSC-VVPCSGNFTQRRGTILSPGYPEPYG-NNLNCIWKIIVTEGSGIQ-IQVISFATEQN 1853
P C +PC+ + + GT+ +P G ++ + I EG + + +
Sbjct: 503 PECQAIPCTPLLSPQNGTMTC---VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR 559
Query: 1854 WDS----LEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAG-FHLEY 1908
W E ++ AP GS + N S HF D G ++E
Sbjct: 560 WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGST---CHFSCDNGFKLEGPNNVEC 616
Query: 1909 KTVGLAACQEP------ALPSNSIKI--------GDRYM--------VNDVLSFQCEPGY 1946
T G + P +LP+ ++ G Y N F C G+
Sbjct: 617 TTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGF 676
Query: 1947 TLQGRSHISCMPGTVRRWNYPSPLCIA 1973
TL G S +SC P +W +P C A
Sbjct: 677 TLIGDSTLSCRPS--GQWTAVTPACRA 701
Score = 54.7 bits (130), Expect = 2e-06
Identities = 107/465 (23%), Positives = 162/465 (34%), Gaps = 86/465 (18%)
Query: 528 CGDPGIPAYGKRT----GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-V 582
C IP G T +F H + +F C F LVG V+ C + W+ P C
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKA 321
Query: 583 FSCFFNFTASSGII--LSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLA 640
C S G + + P YG++ +PG R+ + D L
Sbjct: 322 VQCQHLEAPSEGTMDCVHPLTAFAYGSSCK----FECQPGYRVRGL----------DMLR 367
Query: 641 VKDDG-----------ISDITVLGTFSGN-EVPSQLASSGHIVRLEFQSDHSTTGRGFNI 688
D G IS + G+ + L + + F+ RG +I
Sbjct: 368 CIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADI 427
Query: 689 TYT-TFGQ----------NECHDPGIPINGR-----RFGDRFLLGSSVSFHCDDGFVKTQ 732
GQ +C D +P R FG F S SF C++G +
Sbjct: 428 VRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFG-AFRYQSVCSFTCNEGLLLV- 485
Query: 733 GSESITCILQDGNVVWSSTVPRCEA-PCGGHLTASSGVI--LPPGWPGYYKDSLHCEWII 789
G+ + C L GN W+S P C+A PC L+ +G + + P YK + C++I
Sbjct: 486 GASVLQC-LATGN--WNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKST--CQFIC 540
Query: 790 EAKPGHSIKITFDRFQTEVNYDTLEV------------RDGPASSSPLIGEYHGTQAPQF 837
+ S D ++ D+ + G S GE++ F
Sbjct: 541 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF 600
Query: 838 LISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLD-PGI-------PVNG----HR 885
G + L +N + T + + L PG+ P G
Sbjct: 601 SCDNG---FKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRH 657
Query: 886 HGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL 930
H G FG +T F C+ G+TL D L C + QW P+C A+
Sbjct: 658 HPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAV 702
Score = 54.3 bits (129), Expect = 2e-06
Identities = 90/434 (20%), Positives = 149/434 (34%), Gaps = 87/434 (20%)
Query: 159 TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSS 218
T F G ++ C PGY + G +L CI S W P P C A
Sbjct: 342 TAFAYGSSCKFECQPGYRVRGLDMLRCIDS----GHWSAPLPTCEA-------------- 383
Query: 219 ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMN 278
IS S + DC+ ++ A DT F+ EG+ + L
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNC----SFRCAEGFMLRGADIVRCDN--LGQWT 437
Query: 279 LPSPVISSKNWLRLHFTSDS----NHRRKGFNAQ----FQVKKAIELKSRGVKMLPSKDG 330
P+PV + L +++ +H F Q F + + L G +L
Sbjct: 438 APAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLV--GASVLQCLAT 495
Query: 331 SHKNSVLSQ-GGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSIT 389
+ NSV + + + P G + GS S + QF C++ Y L G + +
Sbjct: 496 GNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGS--SSYKSTCQFICDEGYSLSGPERLD 553
Query: 390 CQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDK 449
C R W+D P+C A C G + + ++ + C
Sbjct: 554 CTR----SGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC----------- 598
Query: 450 VIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTG--SSVPDLIVSMSNQMWLHLQS 507
F + G+ K+ +V +G S+ P ++
Sbjct: 599 -------HFSCDNGF---------KLEGPNNVECTTSGRWSATPPTCKGIA--------- 633
Query: 508 DDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVIT 567
S+ +PG + + G G Y + +F T F C A F L+G+ ++
Sbjct: 634 --SLPTPGVQC--PALTTPGQG----TMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLS 685
Query: 568 CQQNNQWSGNKPSC 581
C+ + QW+ P+C
Sbjct: 686 CRPSGQWTAVTPAC 699
Score = 53.9 bits (128), Expect = 3e-06
Identities = 119/583 (20%), Positives = 187/583 (32%), Gaps = 137/583 (23%)
Query: 1243 YSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNN 1302
+SC G+A+ G + C + VW P P C A + A + G + +
Sbjct: 290 FSCEEGFALVGPEVVQCTASG--VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYG 347
Query: 1303 LHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTF 1362
C + E PG + ++ + H W P+ + + S L +H +
Sbjct: 348 SSCKF--ECQPGYRVRGLDMLRCIDSGH-----WSAPLPT---CEAISCEPLESPVHGSM 397
Query: 1363 NSL----TLQFDSDF-FISKSGFSIQFSTSI----------------AATCNDPGMPQNG 1401
+ Q+D++ F GF ++ + + A C D +P N
Sbjct: 398 DCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVP-NE 456
Query: 1402 TRYGDSREAG-----DTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL 1456
R S G +F C+ G L G + + C+ N W PP C A
Sbjct: 457 ARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGN---WNSVPPECQAI----- 508
Query: 1457 TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNS 1516
P +LSP N S + + + F+ D
Sbjct: 509 --PCTPLLSPQ-----------------NGTMTCVQPLGSSSYKSTCQFIC-----DEGY 544
Query: 1517 PLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTR 1576
L G PER++ + + + +D+ P + D +
Sbjct: 545 SLSG-------PERLDCTRSGRW----TDSPPMCEAIKCPELFAPEQGSLDCSDTRG--- 590
Query: 1577 VGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGV 1636
+F +GST + CD+G+K+ P+++ C W P+C G +
Sbjct: 591 ---EFNVGSTCHFSCDNGFKLEGPNNVECTTSG----RWSATPPTCKGIASLPTPGVQCP 643
Query: 1637 VLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLS 1696
L+ T GQ +Y P F F YF G +A L+
Sbjct: 644 ALT-------TPGQGTMYCRHHPGTF-GFNTTCYF------------GCNAGFTLIGD-- 681
Query: 1697 GSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGS 1756
TL S Q A H V + CS+ +
Sbjct: 682 -----STLSCRPSGQWTAVTPACRAVKCSELH-----VNKPIAMNCSN---------LWG 722
Query: 1757 EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
FS GSI F C G LL GS CQ W+ T+P+C
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQE----NGHWSTTVPTC 761
Score = 45.4 bits (106), Expect = 0.001
Identities = 60/285 (21%), Positives = 101/285 (35%), Gaps = 53/285 (18%)
Query: 145 CGN---PGEILKGVLHGT-RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAP 200
CG P +L H F+ + + C GY + G + L C+ S W P
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLAS----GIWTNKPP 255
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYD 260
C A C +++ H +++ + C+ F EEG+
Sbjct: 256 QCLA-AQCPPLKIPERGNMTCLHSAKAFQHQSSCS-----------------FSCEEGFA 297
Query: 261 FL--EISGTEAPSIWLTGMNLPSPVISSKNWLRLHF----TSDSNHRRKGF----NAQFQ 310
+ E+ A +W P+PV + L T D H F + +F+
Sbjct: 298 LVGPEVVQCTASGVW----TAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFE 353
Query: 311 VKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-- 368
+ + RG+ ML D H ++ L + C P +G S R
Sbjct: 354 CQPGYRV--RGLDMLRCIDSGHWSAPLP----TCEAISCEPLESPVHGSMDCSPSLRAFQ 407
Query: 369 -GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC 412
N F C + ++L+G+ + C + L W+ P+C+A C
Sbjct: 408 YDTNCSFRCAEGFMLRGADIVRC----DNLGQWTAPAPVCQALQC 448
Score = 41.6 bits (96), Expect = 0.014
Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 12/84 (14%)
Query: 2081 QAYELQNCPDPPPFQNGYMINSDYSVG----QSV-SFECYPGYILIGHPVLTCQHGINRN 2135
QA + Q+ P P N +N + G QSV SF C G +L+G VL C N
Sbjct: 444 QALQCQDLPVP----NEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCL--ATGN 497
Query: 2136 WNYPFPRCDA-PCGYNVTSQNGTI 2158
WN P C A PC ++ QNGT+
Sbjct: 498 WNSVPPECQAIPCTPLLSPQNGTM 521
Score = 40.4 bits (93), Expect = 0.032
Identities = 49/240 (20%), Positives = 72/240 (30%), Gaps = 65/240 (27%)
Query: 349 CPDPGIPENGRRAGSDFSRV---GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRP 405
CP IPE G ++ ++ FSCE+ + L G + + C W+ P
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQC----TASGVWTAPAP 317
Query: 406 ICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYD 465
+C+A C +L PS E CV +T K + RG D
Sbjct: 318 VCKAVQC-QHLEAPS------------EGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLD 364
Query: 466 TLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEK 525
L D+G + A E
Sbjct: 365 MLRCIDSGH-----------------------------------------WSAPLPTCEA 383
Query: 526 GGCGDPGIPAYGKRTGS----SFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
C P +G S +F + +F C F L G ++ C QW+ P C
Sbjct: 384 ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVC 443
Score = 37.4 bits (85), Expect = 0.27
Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 11/123 (8%)
Query: 1021 LRFISDFSIS-YEGFNITFSEYDLEPCDDPGVPAF-----SRRIGFHFGVGDSLTFSCFL 1074
L I +++ S Y GF EY E C + +P S +G +F +F C
Sbjct: 175 LETIGNYTCSCYPGFYGPECEYVRE-CGELELPQHVLMNCSHPLG-NFSFNSQCSFHCTD 232
Query: 1075 GYRLEGATKLTCLGGGRRVWSAPLPRCV-AECGASVKGNEGTLLSPNFPSNYDNNHECIY 1133
GY++ G +KL CL G +W+ P+C+ A+C G + + + + C +
Sbjct: 233 GYQVNGPSKLECLASG--IWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSF 290
Query: 1134 KIE 1136
E
Sbjct: 291 SCE 293
Score = 37.4 bits (85), Expect = 0.27
Identities = 43/210 (20%), Positives = 73/210 (34%), Gaps = 53/210 (25%)
Query: 1415 TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPP 1474
+F C GYQ+ G +K+ C+ W PP C+AA PP
Sbjct: 227 SFHCTDGYQVNGPSKLECLASG---IWTNKPPQCLAA-------------------QCPP 264
Query: 1475 GKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESS 1534
K + + K+F + S F + L+G PE ++ +
Sbjct: 265 LK-----IPERGNMTCLHSAKAFQHQSSCSF-----SCEEGFALVG-------PEVVQCT 307
Query: 1535 GNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSG 1594
+ ++ A + + E P E D + + T F GS+ ++C G
Sbjct: 308 ASGVWTA----PAPVCKAVQCQHLEAPSEGTMDCVHPL------TAFAYGSSCKFECQPG 357
Query: 1595 YKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
Y++ + C+ W LP+C A
Sbjct: 358 YRVRGLDMLRCI----DSGHWSAPLPTCEA 383
Score = 37.4 bits (85), Expect = 0.27
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 2277 FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
F G K++C PGY + G D+L C S + LPTCEA
Sbjct: 344 FAYGSSCKFECQPGYRVRGLDMLRCIDSG--HWSAPLPTCEA 383
Score = 37.0 bits (84), Expect = 0.35
Identities = 55/274 (20%), Positives = 90/274 (32%), Gaps = 45/274 (16%)
Query: 150 EILKGVLHGTR--------FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
E L+ +HG+ F + C G++L G I+ C N W PAP
Sbjct: 387 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRC----DNLGQWTAPAPV 442
Query: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWT----ILAEPGDTIALVFTDFQLEE 257
C+A C + ++ H + + C++T +L + + T
Sbjct: 443 CQAL-QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSV 501
Query: 258 GYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
+ I T S M P+ SS F D + G
Sbjct: 502 PPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSG------------- 548
Query: 318 KSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFS---RVGANVQF 374
P + ++ + + CP+ PE G SD VG+ F
Sbjct: 549 --------PERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF 600
Query: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
SC++ + L+G ++ C T WS P C+
Sbjct: 601 SCDNGFKLEGPNNVEC----TTSGRWSATPPTCK 630
Score = 36.2 bits (82), Expect = 0.60
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 2104 YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDA 2145
++ G S FEC PGY + G +L C + +W+ P P C+A
Sbjct: 344 FAYGSSCKFECQPGYRVRGLDMLRCID--SGHWSAPLPTCEA 383
Score = 35.4 bits (80), Expect = 1.0
Identities = 96/467 (20%), Positives = 155/467 (33%), Gaps = 69/467 (14%)
Query: 1388 IAATCNDPGMPQNGT----RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQP 1443
+AA C +P+ G + + + +F C+ G+ L G + C W
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTA 314
Query: 1444 DPPTCIAACGGNLTGPAGVILSPNYP-QPYPPGKECDWRVKVNPDFVIALI-----FKSF 1497
P C A +L P+ + +P + G C + + P + + + S
Sbjct: 315 PAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSC--KFECQPGYRVRGLDMLRCIDSG 372
Query: 1498 NMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
+ E SP+ GS S + + N +FR L G I
Sbjct: 373 HWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNC---SFRCAEGFMLRGADIVR 429
Query: 1558 KEK------PREAC----FDPGNIMNGTRVGTD-----FKLGSTITYQCDSGYKILDPSS 1602
+ P C + N RV F+ S ++ C+ G ++ S
Sbjct: 430 CDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASV 489
Query: 1603 ITCVIGADGKPSWDQVLPSCNA-PCGGQYTGSEGVV--LSPNYPHNY--TAGQICL--YS 1655
+ C+ A G +W+ V P C A PC + G + + P +Y T IC YS
Sbjct: 490 LQCL--ATG--NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYS 545
Query: 1656 ITVPKEF--VVFGQFAYFQTALNDLA--ELFDGTHAQARLLSSLSGSHSGETLPLATSNQ 1711
++ P+ G++ + ELF + + G T + N
Sbjct: 546 LSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNG 605
Query: 1712 ILLRFSAKSGASARGFHFVYQAVPRTSD---------TQCSSVPEPRYG----RRIGSEF 1758
L + G + A P T QC ++ P G R F
Sbjct: 606 FKLEGPNNVECTTSGR---WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTF 662
Query: 1759 SAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC-VVPCS 1804
+ F CN G+ L G + L C+ QW P+C V CS
Sbjct: 663 GFNTTCYFGCNAGFTLIGDSTLSCR----PSGQWTAVTPACRAVKCS 705
Score = 33.9 bits (76), Expect = 3.0
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 703 IPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEA 757
I +N F GS SFHC +G + GS C N WS+TVP C+A
Sbjct: 713 IAMNCSNLWGNFSYGSICSFHCLEGQL-LNGSAQTAC---QENGHWSTTVPTCQA 763
Score = 33.5 bits (75), Expect = 3.9
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDA 929
I +N G+F S +F C G L+ C+ N W+ +P+C A
Sbjct: 713 IAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQA 763
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 249 bits (637), Expect = 3e-65
Identities = 187/614 (30%), Positives = 287/614 (46%), Gaps = 37/614 (6%)
Query: 1059 GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLS 1118
G G+ ++T S G E T T + P P C + G EG+L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1119 P-NFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKV--YDGKDSSSRPLGTFT 1175
P + S D +C + I G G+ ++ ++ L EG+T+ V G D PL
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD----PLPLAN 313
Query: 1176 KNELL-GLILNSTSNHLWLEFNTNGSDTDQG-FQLTYTSFDLVKCEDPGIPNYGYRIRDE 1233
++ LL G ++ S ++ L F + G F Y ++ L+ C P P YG
Sbjct: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
Query: 1234 GHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSP 1293
H + + C GY + G+ LTCL+ + WD P CIA CGG I AT+GRI+SP
Sbjct: 373 LHPGGSA-RFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
Query: 1294 GYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP-VDSDILLKEWSGS 1352
G+P Y NNL C W++EA G+ + LHF D L + +G V++ + +
Sbjct: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
Query: 1353 ALP-EDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQ-NGTRYGDSREA 1410
LP E + S+ ++ +D + +G ++++ C +P + N + +
Sbjct: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1411 GDTVTFQCDPGYQL-QGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYP 1469
G TV F CDPGY L QG I CV ++ W P C A C G +T AGV+LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1470 QPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPE 1529
+PY G++C W V V D I L + + P D L Y+G+D + ++G Y G ++
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1530 RIESSGNSLFLAFRSDASVGL----SGFAIEFKEKPR-EACFDPGNIMNGTRVGTDFKL- 1583
++ +S + + F+SD + GF I F E PR + C + I NG + + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1584 -GSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCG----GQYTGSEGVVL 1638
G+ +TYQC GY+++ S + C +W + LPSC G S ++
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1639 SPNYPHNYTAGQIC 1652
SP +P T IC
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 232 bits (592), Expect = 4e-60
Identities = 188/707 (26%), Positives = 291/707 (41%), Gaps = 63/707 (8%)
Query: 1802 PCSGNFTQRRGTILSP-GYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
PCS NF+ G++ SP P L+C + I V G G++I+V + + + +++ +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVE 301
Query: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAG-FHLEYKTVGLAACQEP 1919
G L + S ++ S ++Q L FQS A G FH Y+ L +C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFP 360
Query: 1920 ALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTL 1979
P+ F C GY L+G H++C+ T W+ P+CIA CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 1980 -STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP-YH 2037
+ G I+SPGFPG+Y NNL C W + P G H+ F S + D L I+NG
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2038 TSPMIGQFSGTDLP-AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP-PPFQ 2095
P+ + LP LLS+ + +D S G L Y+A++ +C +P +
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2096 NGYMINSDYSVGQSVSFECYPGYIL-IGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQ 2154
N Y VG +V F C PGY L G ++ C + WN P C A C +T
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2155 NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL 2214
G + SP +P+ Y +DCIW + V + ++ +L+ D + +DG D + L
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVL 659
Query: 2215 GVFSGNTALETAYSSTNQVLLKFHSDFSNG------GFFVLNFHAFQLKKCQPPPAVPQA 2268
G +SG + ++S V ++F SD GF + F + C P +P
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2269 EMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTG 2328
+ G V YQC+PGY +VG+ +L C+ L + LP+C+ ++
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQW--DLTWSEDLPSCQRVTSCHD---- 773
Query: 2329 SSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPL 2388
PG+ +S+ S K + D L D +G SP
Sbjct: 774 ----------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAG-SP- 821
Query: 2389 LVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRT 2448
+WS D A + P L+ P +
Sbjct: 822 -----------------------KWS-DRAPK---CLLEQLKPCHGLSAPENGARSPEKQ 854
Query: 2449 AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
G+ +H+ C PGY + G ++ C P W P+C+A S
Sbjct: 855 LHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPICRAAS 899
Score = 212 bits (539), Expect = 6e-54
Identities = 172/604 (28%), Positives = 263/604 (43%), Gaps = 83/604 (13%)
Query: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIA 1450
+C+ P P G S G + F C GYQL+G +TC+ F W P CIA
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
Query: 1451 ACGGNL-TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIY 1509
ACGG + G I+SP +P Y C W ++ + L F+ ++ D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 1510 EGEDSNSPLI-GSYQGSQAP-ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD 1567
G++ +P + SY+ P E + SSG F+ +D+S +G A+ ++ + C++
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
Query: 1568 P----GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSIT-CVIGADGKPSWDQVLPSC 1622
P GN + T + +G+T+ + CD GY + S I CV D P W++ P+C
Sbjct: 535 PFVKYGNFSSSTPT---YPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPAC 589
Query: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
A C G+ T S GVVLSPN+P Y GQ C++ + V ++ + + D+ +
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
Query: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASA----RGFHFVYQAVPRTS 1738
DG AR+L SG S L + + ++F + G S +GF + VPR +
Sbjct: 650 DGDDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPR-N 707
Query: 1739 DTQCSSVPEPRYGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
DT C +PE G + S E G++V ++C PGY + GS+ L CQ W++ +
Sbjct: 708 DT-CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDL 762
Query: 1797 PSC--VVPCS--GNFTQRRGTILSPGYPEPYGNNLNCIW-KIIVTEGSGIQIQVISFATE 1851
PSC V C G+ R I SP + P G + I + V GS I
Sbjct: 763 PSCQRVTSCHDPGDVEHSRRLISSPKF--PVGATVQYICDQGFVLMGSSI---------- 810
Query: 1852 QNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
L HD +P+ +S LL
Sbjct: 811 -----LTCHDR-QAGSPK---WSDRAPKCLLEQ--------------------------- 834
Query: 1912 GLAACQEPALPSNSIKIGDRYM--VNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSP 1969
L C + P N + ++ + + F C PGY L+G++ I C+PG W+ P P
Sbjct: 835 -LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPP 893
Query: 1970 LCIA 1973
+C A
Sbjct: 894 ICRA 897
Score = 199 bits (505), Expect = 5e-50
Identities = 153/556 (27%), Positives = 247/556 (44%), Gaps = 28/556 (5%)
Query: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGD 471
C N GP G + SP D + + P +++ + L G +T+TV
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVEG 302
Query: 472 AGKVGDT--RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCG 529
G + ++L G +I S ++Q L QS PG + + C
Sbjct: 303 LGGPDPLPLANQSFLLRGQ----VIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 530 DPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ--WSGNKPSCVFSCFF 587
P PAYG T +S G + F C ++L G R +TC Q W +P C+ +C
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
Query: 588 NF-TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKD-DG 645
A++G I+SP +P Y NN+ C WL+ + G R+HL F + D L +++ D
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 646 ISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIP 704
+ V ++ +P + L SSG +E +D S G + Y F Q C++P +
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
Query: 705 I-NGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHL 763
N + +G++V F CD G+ QGS I C+ + W+ T P C A C G +
Sbjct: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
Query: 764 TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSS 823
T S+GV+L P WP Y C W + + I + + D L DG ++
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
Query: 824 PLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSI----GFLIHYESVTLESDSCLD-PG 878
++G+Y G ++ L ++ + + F +D S + GF+IH+ V +D+C + P
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVP-RNDTCPELPE 715
Query: 879 IPVNGHRHGG--DFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG---- 932
IP NG + + + VT+ C PGY + L+C+ + W+ LPSC +
Sbjct: 716 IP-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 933 GYIQGKSGTVLSPGFP 948
G ++ + SP FP
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 188 bits (478), Expect = 7e-47
Identities = 186/716 (25%), Positives = 292/716 (40%), Gaps = 86/716 (12%)
Query: 585 CFFNFTASSGIILSP---NYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
C +NF+ G + SP + P + G ++C + I PG + + + + + + + V
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNISLR-EGETVTV 300
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRG-FNITYTTFGQNECHD 700
+ G D L S + S H L FQS G G F+ Y + + CH
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
Query: 701 PGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCG 760
P P G G S FHC G+ + +G+ +TC L W S P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACG 417
Query: 761 GHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGP 819
G + A++G I+ PG+PG Y ++L C W++EA G + + F++ + D L +R+G
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 820 -ASSSPLIGEYHGTQAP-QFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
+ P+ Y P + L+S+G ++ +TD+S ++ G + YE+ + C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEA--FQQGHCYEP 535
Query: 878 GIPV-NGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLV-CERNH--QWNHALPSCDALCGG 933
+ N + + +TV FSCDPGYTL ++ C H QWN P+C A+C G
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSG 595
Query: 934 YIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSF 993
I +G VLSP +P+ Y +C W + V K + + + +L DG
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGD--VLTFYDG-- 651
Query: 994 SEPVARLTGSVLPHTIKAGLFGNFT-AQLRFISDFSIS----YEGFNITFSEYDL-EPCD 1047
+ AR+ G LF + ++F SD S +GF I F E + C
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 1048 D-PGVP-AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC--VA 1103
+ P +P + G +T+ C+ GY++ G++ L C WS LP C V
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVT 769
Query: 1104 EC--GASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
C V+ + + SP FP + C + F L L +
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFVLMGSSILTCH 814
Query: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDP 1221
D + S + W SD L L C
Sbjct: 815 DRQAGSPK----------------------W-------SDRAPKCLLE----QLKPCHGL 841
Query: 1222 GIPNYGYRIRDEG-HFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
P G R ++ H + +SC PGY + G ++ C+ G W P P C A
Sbjct: 842 SAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 187 bits (474), Expect = 2e-46
Identities = 179/652 (27%), Positives = 271/652 (41%), Gaps = 49/652 (7%)
Query: 1999 LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTT 2058
LDC + IS+ GYG I+ N S G P+ Q S + S T
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQ-SFLLRGQVIRSPT 327
Query: 2059 HETLIHFYSDHSQNRQG-FKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPG 2117
H+ + F S G F YQAY L +C P G + + G S F C G
Sbjct: 328 HQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATG 386
Query: 2118 YILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWL 2176
Y L G LTC + W+ P C A CG + + G I SPGFP Y C WL
Sbjct: 387 YQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
Query: 2177 ITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL--GVFSGNTALETAYSSTNQVL 2234
+ P G ++++F + +D + + +G + +P + +E SS
Sbjct: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFF 506
Query: 2235 LKFHSDFSNGGF-FVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTL 2293
++ +D S L + AFQ C P V + + +G V++ C PGYTL
Sbjct: 507 VELSTDSSGAAAGMALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
Query: 2294 V-GTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSI 2352
G+ I+ C Q+ + P C A C + E+ T S+GV+LSP +P Y Q C W +
Sbjct: 566 EQGSIIIECVDPHDPQWNETEPACRAVC-SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGV 623
Query: 2353 KVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLR 2412
VE + I + + + D L +DG + +L SG + FTS ++ + ++
Sbjct: 624 HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQ 681
Query: 2413 WSTDHATSKKGFKIRYAAPY--------CSLTHPLKNGGILNRTAGAV-GSKVHYFCKPG 2463
+ +D TS G++ + + C + NG V G+ V Y C PG
Sbjct: 682 FQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPG 741
Query: 2464 YRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCGIPESPGNGS--FTGNEFTLDSKVVY 2520
Y++VG S C+ + W P CQ V SC P + + +F + + V Y
Sbjct: 742 YQVVGSSVLMCQWD----LTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQY 797
Query: 2521 ECHEGFKLESSQQATAVCQEDG--LWSNKG--------KPPTCKPVACPSIEAQLSEHVI 2570
C +GF L S T ++ G WS++ KP C ++ P A+ E
Sbjct: 798 ICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKP--CHGLSAPENGARSPEK-- 853
Query: 2571 WRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVIS 2622
L+ GA + SC+PGY L+G ++C + D P CR S
Sbjct: 854 ------QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 179 bits (454), Expect = 4e-44
Identities = 191/722 (26%), Positives = 286/722 (39%), Gaps = 80/722 (11%)
Query: 751 TVPRCEAPCGGHLTASSGVILPPGWPGYYKD-SLHCEWIIEAKPGHSIKITFDRFQT-EV 808
T + PC + + G + P D L C + I PG+ ++I E
Sbjct: 236 TTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG 295
Query: 809 NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIG-FLIHYESV 867
T+E GP PL + + Q + S + L F + + G F HY++
Sbjct: 296 ETVTVEGLGGP-DPLPLANQSFLLRG-QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY 353
Query: 868 TLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ--WNHALP 925
L SC P P G + F C GY L L C Q W+ P
Sbjct: 354 LL---SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEP 410
Query: 926 SCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDY 984
C A CGG I+ + G ++SPGFP Y N+L C W +E G+ + + F L D
Sbjct: 411 VCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR 470
Query: 985 LLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLE 1044
L+I + P + V I+ L + +D S + G + + +
Sbjct: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
Query: 1045 PCDDPGVPA--FSRRIGFHFGVGDSLTFSCFLGYRLE-GATKLTCLGGGRRVWSAPLPRC 1101
C +P V FS + VG ++ FSC GY LE G+ + C+ W+ P C
Sbjct: 531 HCYEPFVKYGNFSSSTPT-YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 1102 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
A C + + G +LSPN+P Y +CI+ + E K I L R ++ GD L Y
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
Query: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS--FDLVK-- 1217
DG D ++R LG ++ + S ++ + ++F ++ + G+Q + F++ +
Sbjct: 650 DGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 1218 -CED-PGIPNYGYRIRDEGHFTD-TVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
C + P IPN G++ + TVV Y C PGY + GS+ L C W + LPSC
Sbjct: 709 TCPELPEIPN-GWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1275 --IAECGGQIHAATSGRILS-PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHD 1331
+ C S R++S P +P C D G + M
Sbjct: 766 QRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----------MGSS 809
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
IL D S +WS A P+ +
Sbjct: 810 ILTCHDRQAGSP----KWSDRA-PKCLLEQLKP--------------------------- 837
Query: 1392 CNDPGMPQNGTRYGDSR--EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI 1449
C+ P+NG R + + AG T+ F C PGY L+GQA I CV + W PP C
Sbjct: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVP-GHPSHWSDPPPICR 896
Query: 1450 AA 1451
AA
Sbjct: 897 AA 898
Score = 164 bits (416), Expect = 1e-39
Identities = 149/567 (26%), Positives = 239/567 (42%), Gaps = 46/567 (8%)
Query: 1452 CGGNLTGPAGVILSP-NYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYE 1510
C N +GP G + SP + P G +C + + V P + + + ++ ++ E
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 1511 GEDSNSPL-IGSYQGSQAPERIESSGNSLFLAFRS-DASVGLSGFAIEFKEKPREACFDP 1568
G PL + + + I S + L F+S G F ++ +C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGG 1628
G T G + + C +GY++ +TC+ +P WD P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
Query: 1629 QY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE------L 1681
+ G ++SP +P NY+ C + + P+ GQ + LAE +
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLII 473
Query: 1682 FDGTHAQARLLSSLSGSHSGETLP----LATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
+G + +A + S+ E LP L++ + S S +A G Y+A +
Sbjct: 474 RNGDNVEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
Query: 1738 SDTQCSSVPEPRYGRRIGSE--FSAGSIVRFECNPGYLL-QGSTALHCQSVPNALAQWND 1794
+ P +YG S + G+ V F C+PGY L QGS + C + QWN+
Sbjct: 531 HCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNE 584
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
T P+C CSG T G +LSP +PEPYG +CIW + V E I + +
Sbjct: 585 TEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG- 643
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE-----YK 1909
D L +DG D+TA LG +SG L ++ + + FQSD + G+ ++
Sbjct: 644 DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 703
Query: 1910 TVGLAACQE-PALPSNSIKIGDRYMVN-DVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1967
C E P +P+ +V+ V+++QC PGY + G S + C + P
Sbjct: 704 VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLP 763
Query: 1968 SPLCIATC--GGTLSTLGGVILSPGFP 1992
S + +C G + +I SP FP
Sbjct: 764 SCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 158 bits (400), Expect = 8e-38
Identities = 170/672 (25%), Positives = 254/672 (37%), Gaps = 98/672 (14%)
Query: 887 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSP- 945
G GI+ T+T S G D+E C G G++ SP
Sbjct: 203 GAGIGIQGTITSSTASG---DDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPT 259
Query: 946 GFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVL 1005
L+C + I V G GV++ L + G P+A + +
Sbjct: 260 DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLR 319
Query: 1006 PHTIKAGLFGNFTAQLRFISDFSISYEG-FNITFSEYDLEPCDDPGVPAFSRRIGFHFGV 1064
I++ A LRF S + G F+ + Y L C P PA+
Sbjct: 320 GQVIRSP---THQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1065 GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPS 1123
G S F C GY+L+GA LTCL + W + P C+A CG ++ G ++SP FP
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 1124 NYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT-LKVYDGKDSSSRPLGTFTKNELLGL 1182
NY NN C + +E G+ +HL L E D L + +G + + P+ + E L +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 1183 I-LNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVV 1241
L S+ H ++E +T+ S G L Y +F C +P + + + T V
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTV 555
Query: 1242 LYSCNPGYAMH-GSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYD 1300
+SC+PGY + GS + C+ W++ P+C A C G+I ++G +LSP +P PY
Sbjct: 556 EFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI-TDSAGVVLSPNWPEPYG 614
Query: 1301 NNLHCTWIIEADPGKTISL----------------------------------HFIVFDT 1326
C W + + K I L HF +F T
Sbjct: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLF-T 673
Query: 1327 EMAHDILKVWDGPVDSDILLKE------------------------WSGSALPEDIHSTF 1362
MA ++ P S + ++ W + PE +H T
Sbjct: 674 SMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTV 733
Query: 1363 ------------NSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSRE- 1409
S L D S+ S Q TS C+DPG ++ R S +
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS----CHDPGDVEHSRRLISSPKF 789
Query: 1410 -AGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTC----IAACGGNLTGPAGVI 1463
G TV + CD G+ L G + +TC W P C + C G L+ P
Sbjct: 790 PVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG-LSAPENGA 848
Query: 1464 LSPNYPQPYPPG 1475
SP Q +P G
Sbjct: 849 RSPE-KQLHPAG 859
Score = 155 bits (391), Expect = 9e-37
Identities = 182/749 (24%), Positives = 289/749 (38%), Gaps = 118/749 (15%)
Query: 206 GACGGTLRGTSSSISSP-HFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
G C G S+ SP S + DC + I PG + + + L EG + + +
Sbjct: 242 GPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTV 300
Query: 265 SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKM 324
G P P P+ + LR H+ A+ +S
Sbjct: 301 EGLGGPD--------PLPLANQSFLLRGQVIRSPTHQA-----------ALRFQSLPPPA 341
Query: 325 LPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQG 384
P H + L C P P G + G + +F C Y L+G
Sbjct: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSL-HPGGSARFHCATGYQLKG 391
Query: 385 SKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS-GVITSPNYPVQYEDNAHCVWVIT 443
++ +TC T+ W P+C A CG +R + G I SP +P Y +N C W++
Sbjct: 392 ARHLTCLNATQPF--WDSKEPVCIA-ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLE 448
Query: 444 TTDPDKVIKLAFEEFELERGYDTLTV--GD---AGKVGDTRSVLYVLTGSSVPDLIVSMS 498
+ + + L FE+ L D L + GD A V D+ V Y+ ++S
Sbjct: 449 APEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEG-----LLSSG 502
Query: 499 NQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLH--GDTLTFECPA 556
++ L +D S + G Y+ ++G C +P + YG + S+ + G T+ F C
Sbjct: 503 KHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK-YGNFSSSTPTYPVGTTVEFSCDP 561
Query: 557 AFELV-GERVITC--QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVW 613
+ L G +I C + QW+ +P+C C T S+G++LSPN+PE YG +C+W
Sbjct: 562 GYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIW 621
Query: 614 LIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRL 673
+ E RI L + P D L D VLG +SG +L +S V +
Sbjct: 622 GVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTI 680
Query: 674 EFQSDHSTT----GRGFNITYTTFGQNE-CHD-PGIPINGRRFGDR--FLLGSSVSFHCD 725
+FQSD T+ +GF I + +N+ C + P IP NG + + + G+ V++ C
Sbjct: 681 QFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQCY 739
Query: 726 DGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHC 785
G+ + GS + C ++ WS +P C+ H PG D H
Sbjct: 740 PGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCH---------DPG------DVEHS 780
Query: 786 EWIIEAKP---GHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTG 842
+I + G +++ D+ + L D A S +AP+ L+
Sbjct: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK-----WSDRAPKCLLEQL 835
Query: 843 NFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDP 902
+ L +N S +H +T+ FSC P
Sbjct: 836 KPCHGLSAPENGARSPEKQLHPAG---------------------------ATIHFSCAP 868
Query: 903 GYTLSDDEPLVCERNH--QWNHALPSCDA 929
GY L + C H W+ P C A
Sbjct: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 135 bits (340), Expect = 7e-31
Identities = 130/478 (27%), Positives = 194/478 (40%), Gaps = 62/478 (12%)
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+C P G + T + G R+ C GY L+G LTC+ + WD P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNA--TQPFWDSKEPVCI 413
Query: 204 AEGACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFL 262
A ACGG +R T+ I SP FP Y NN C W + A G + L F L E D L
Sbjct: 414 A--ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
Query: 263 EI---SGTEAPSIWLTGMNLPSPV---ISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
I EAP ++ + P+ +SS + ++DS+ G +++
Sbjct: 472 IIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE------ 525
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSC 376
A C +P + + + VG V+FSC
Sbjct: 526 --------------------------AFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSC 559
Query: 377 EDNYVL-QGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
+ Y L QGS I C V W++ P CRA C + +GV+ SPN+P Y
Sbjct: 560 DPGYTLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRG 616
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
C+W + + DK I L + G D LT D + T VL +G +
Sbjct: 617 QDCIWGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLF 672
Query: 496 SMSNQMWLHLQSDDSIG----SPGFKAVYQEIEKGG-CGD-PGIP-AYGKRTGSSFLHGD 548
+ + + QSD GF + E+ + C + P IP + + +HG
Sbjct: 673 TSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGT 732
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC--VFSCF--FNFTASSGIILSPNYP 602
+T++C +++VG V+ CQ + WS + PSC V SC + S +I SP +P
Sbjct: 733 VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 116 bits (291), Expect = 3e-25
Identities = 107/422 (25%), Positives = 163/422 (38%), Gaps = 53/422 (12%)
Query: 32 CGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYD 90
CGG+++ G I SPGFP Y N C W++ E R+ L F +L ED D L + +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 91 GQ-----PQQGNLKVRLSGFQLP-SSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
G P + +V LP ++S+G + +TD + +A G YE
Sbjct: 476 GDNVEAPPVYDSYEVE----YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGH 531
Query: 145 CGNPGEILKGVLHGT-RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
C P T + +G + +SC PGY LE +I+ V P + W+ P CR
Sbjct: 532 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDP-HDPQWNETEPACR 590
Query: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
A C G + ++ + SP++P Y DC W + E I L ++ G
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF 648
Query: 264 ISGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
G + + L +G + +S + + F SD G+ F + ++
Sbjct: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 321 GVKMLPSKDGSHKNS--------------------------VLSQGGVALVSDM------ 348
LP K+ ++ Q + D+
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 349 --CPDPGIPENGRR-AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRP 405
C DPG E+ RR S VGA VQ+ C+ +VL GS +TC WSD P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 406 IC 407
C
Sbjct: 829 KC 830
Score = 105 bits (261), Expect = 1e-21
Identities = 99/371 (26%), Positives = 158/371 (42%), Gaps = 24/371 (6%)
Query: 2146 PCGYNVTSQNGTIYSP-GFPDEYPILKDCIWLITVPPGHGVYI---NFTLLQTEAVNDYI 2201
PC +N + G++ SP + DC + I+V PG+GV I N +L + E V +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
Query: 2202 AVWDGPDQN--SPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH-AFQLKK 2258
GPD + Q + G + S T+Q L+F S G +FH L
Sbjct: 301 EGLGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS 356
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
C P ++ G ++ C GY L G LTC ++Q ++ P C A
Sbjct: 357 CHFPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA 414
Query: 2319 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEV 2378
C +R ++G I+SPG+PGNY N+ TC W ++ + + + + D L +
Sbjct: 415 AC-GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
Query: 2379 FDGSSGQS-PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCS 2434
+G + ++ P+ + S ++ STD + + G +RY A +C
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
Query: 2435 LTHPLKNGGILNRT-AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQA 2493
+K G + T VG+ V + C PGY + S +P QW+ P C+A
Sbjct: 534 EPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRA 591
Query: 2494 VSCG-IPESPG 2503
V G I +S G
Sbjct: 592 VCSGEITDSAG 602
Score = 105 bits (261), Expect = 1e-21
Identities = 157/651 (24%), Positives = 236/651 (36%), Gaps = 111/651 (17%)
Query: 2348 CSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSN 2407
C + I V P Y + I V S ++ + + V +G G PL + S ++
Sbjct: 271 CFFYISVYPGYGVEIKVQNI-SLREGETVTV-EGLGGPDPLPLANQSFLLRGQVIRSPTH 328
Query: 2408 QLYLRWSTDHATSKKG-FKIRYAAPYCSLTHPLKNG-GILNRTAGAVGSKVHYFCKPGYR 2465
Q LR+ + + G F Y A S P + G + T+ G + C GY+
Sbjct: 329 QAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ 388
Query: 2466 MVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECH-- 2523
+ G + TC WDS P+C A G+ + G F + CH
Sbjct: 389 LKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
Query: 2524 ----EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
EG +L + ++ ++D + P S E + + + G
Sbjct: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE------YLPIEG--- 497
Query: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT 2639
LLS +++E L + + + + C F GN +
Sbjct: 498 ------LLSSGKHFFVE---LSTDSSGAAAGMALRYEAFQQGHCYE-PFVKYGNFSSSTP 547
Query: 2640 VY--GATAIFTCNTGYTLV-GSHVRECLA--NGLWSGSETRCLAGHCGS----------- 2683
Y G T F+C+ GYTL GS + EC+ + W+ +E C A G
Sbjct: 548 TYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSP 607
Query: 2684 --PDPIVNG-------HISGDGFSYRDTVVYQCNPG------------------------ 2710
P+P G H+ D D V + PG
Sbjct: 608 NWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
Query: 2711 -FRLVGTSVRICLQDHKWSGQTPVC-----------VPI--TCGHPGNPAHGFTNGSEFN 2756
F+L + + +Q G + + VP TC +G+ + S+
Sbjct: 668 HFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPE 727
Query: 2757 L--NDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC-RVVNCSDPGFVENAIRHGQQN 2813
L VV + C GY + G S C+ + WS LP+C RV +C DPG VE++ R
Sbjct: 728 LVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISS- 786
Query: 2814 FPESFEYGMSILYHCKKGFYLLGSSALTC----MANGLWDRSLPKCLAIS---CGHPGVP 2866
F G ++ Y C +GF L+GSS LTC + W PKCL C P
Sbjct: 787 --PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAP 844
Query: 2867 ANAVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVC--QEDSHWSGALPHC 2913
N + E L GA +H+SC L G + C SHWS P C
Sbjct: 845 ENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 87.0 bits (214), Expect = 3e-16
Identities = 127/550 (23%), Positives = 185/550 (33%), Gaps = 146/550 (26%)
Query: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL--LNGSWSGLQPVCEAVS 2978
C P PA+G RF C G+QL+G+ TCL W +PVC A +
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA-A 415
Query: 2979 CG------------NPGTP---------------------------------------TN 2987
CG +PG P N
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2988 GMIVSSDGILFSSSVIYACWEGYKTSG---LMTRHCTANGTWTGTAPDCTIIS---CGDP 3041
G V + + S V Y EG +SG + ++G G A C +P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3042 GTLANGIQFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTK--DGRWNPSKPVCKA--- 3095
T + TV + C+PGY +E S I C D +WN ++P C+A
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ-GSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 3096 ---------VLCPQPPPVQNGTVEGSDFRWGSSIS-------------------YSCMDG 3127
VL P P G D WG + + DG
Sbjct: 595 GEITDSAGVVLSPNWPEPYG---RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3128 YQLSHSAILSCEG-RGVWK--GEIPQCLPVFCGDPGIPAEGRLSG--------------- 3169
L+ + G R +K + F DPG G G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3170 --------------KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHN 3215
+ + V +QC + +VGSS +CQ D TWS P+C
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3216 TCPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC----LANLTWSGIQTE 3270
+C DPG H SS + VG+TV + C +G+ + GS+ TC + WS +
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3271 CIP------HACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKA-DMK 3323
C+ H PE A + + L G T+ ++C PG+ L G + +
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEK--QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3324 WTGKSPVCKS 3333
W+ P+C++
Sbjct: 888 WSDPPPICRA 897
Score = 80.5 bits (197), Expect = 3e-14
Identities = 56/207 (27%), Positives = 88/207 (42%), Gaps = 17/207 (8%)
Query: 3098 CPQPPPVQNGTVEGS--DFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV- 3154
CP+ P + NG S + G+ ++Y C GYQ+ S++L C+ W ++P C V
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
Query: 3155 FCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQ----ADGTWSGIQPT 3208
C DPG R +S F + V + C F+L+GSS C WS P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3209 CIDPAHNTCPDPGTPHFGIQNSSRG-YEVGSTVFFRCRKGYHIQGSTTRTCLAN--LTWS 3265
C+ C P G ++ + + G+T+ F C GY ++G + C+ WS
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
Query: 3266 GIQTECIPHACRQPETPAHADVRAIDL 3292
P CR + R++D+
Sbjct: 890 D-----PPPICRAASLDGFYNSRSLDV 911
Score = 76.3 bits (186), Expect = 5e-13
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT-CGHPGNPAHG--FTNGSEFNLND 2759
V YQC PG+++VG+SV +C D WS P C +T C PG+ H + +F +
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGA 793
Query: 2760 VVNFTCNTGYLLQGVSRAQCR----SNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQ 2812
V + C+ G++L G S C + +WS P C ++ C EN R ++
Sbjct: 794 TVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEK 853
Query: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRSLPKCLAIS 2859
+ G +I + C G+ L G +++ C+ W P C A S
Sbjct: 854 QLHPA---GATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 71.6 bits (174), Expect = 1e-11
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 2622 SCGSLSFPPNGNKIGTLT--VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC-LA 2678
+C L PNG K + V+G + C GY +VGS V C + WS C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2679 GHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC----LQDHKWSGQTP 2732
C P + + IS F TV Y C+ GF L+G+S+ C KWS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2733 VCVPITCGHPGNPAHGFT---NGS---EFNLND---VVNFTCNTGYLLQGVSRAQCRSN- 2782
C+ P HG + NG+ E L+ ++F+C GY+L+G + +C
Sbjct: 829 KCLL----EQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGH 884
Query: 2783 -GQWSSPLPTCRVVN 2796
WS P P CR +
Sbjct: 885 PSHWSDPPPICRAAS 899
Score = 47.4 bits (111), Expect = 3e-04
Identities = 49/158 (31%), Positives = 66/158 (41%), Gaps = 37/158 (23%)
Query: 698 CHDPGIPINGRRF--GDRFLLGSSVSFHCDDGFVKTQGSESITC-ILQDGNVVWSSTVPR 754
CHDPG + RR +F +G++V + CD GFV GS +TC Q G+ WS P+
Sbjct: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV-LMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 755 C----EAPCGGHLTASSGV------ILPPG-------WPGYYKDSLHCEWIIEAKPGHSI 797
C PC G +G + P G PGY L + I+ PGH
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYV---LKGQASIKCVPGHPS 886
Query: 798 ----------KITFDRFQTEVNYDTLEVRDGPASSSPL 825
+ D F N +L+V PA+SS L
Sbjct: 887 HWSDPPPICRAASLDGF---YNSRSLDVAKAPAASSTL 921
Score = 47.0 bits (110), Expect = 3e-04
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 164 GDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACG 209
G I +SC PGY+L+G A + C+ PG+ + W P P CRA G
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCV--PGHPSHWSDPPPICRAASLDG 902
Score = 41.6 bits (96), Expect = 0.014
Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 144 TCGNPGEI--LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
+C +PG++ + ++ +F +G ++Y C G++L G +ILTC W AP
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 202 CRAE 205
C E
Sbjct: 830 CLLE 833
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 249 bits (637), Expect = 3e-65
Identities = 187/614 (30%), Positives = 287/614 (46%), Gaps = 37/614 (6%)
Query: 1059 GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLS 1118
G G+ ++T S G E T T + P P C + G EG+L S
Sbjct: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
Query: 1119 P-NFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKV--YDGKDSSSRPLGTFT 1175
P + S D +C + I G G+ ++ ++ L EG+T+ V G D PL
Sbjct: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD----PLPLAN 313
Query: 1176 KNELL-GLILNSTSNHLWLEFNTNGSDTDQG-FQLTYTSFDLVKCEDPGIPNYGYRIRDE 1233
++ LL G ++ S ++ L F + G F Y ++ L+ C P P YG
Sbjct: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
Query: 1234 GHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSP 1293
H + + C GY + G+ LTCL+ + WD P CIA CGG I AT+GRI+SP
Sbjct: 373 LHPGGSA-RFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
Query: 1294 GYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP-VDSDILLKEWSGS 1352
G+P Y NNL C W++EA G+ + LHF D L + +G V++ + +
Sbjct: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
Query: 1353 ALP-EDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQ-NGTRYGDSREA 1410
LP E + S+ ++ +D + +G ++++ C +P + N + +
Sbjct: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
Query: 1411 GDTVTFQCDPGYQL-QGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYP 1469
G TV F CDPGY L QG I CV ++ W P C A C G +T AGV+LSPN+P
Sbjct: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
Query: 1470 QPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPE 1529
+PY G++C W V V D I L + + P D L Y+G+D + ++G Y G ++
Sbjct: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
Query: 1530 RIESSGNSLFLAFRSDASVGL----SGFAIEFKEKPR-EACFDPGNIMNGTRVGTDFKL- 1583
++ +S + + F+SD + GF I F E PR + C + I NG + + +L
Sbjct: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
Query: 1584 -GSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCG----GQYTGSEGVVL 1638
G+ +TYQC GY+++ S + C +W + LPSC G S ++
Sbjct: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
Query: 1639 SPNYPHNYTAGQIC 1652
SP +P T IC
Sbjct: 786 SPKFPVGATVQYIC 799
Score = 232 bits (592), Expect = 4e-60
Identities = 188/707 (26%), Positives = 291/707 (41%), Gaps = 63/707 (8%)
Query: 1802 PCSGNFTQRRGTILSP-GYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
PCS NF+ G++ SP P L+C + I V G G++I+V + + + +++ +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVE 301
Query: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAG-FHLEYKTVGLAACQEP 1919
G L + S ++ S ++Q L FQS A G FH Y+ L +C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFP 360
Query: 1920 ALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTL 1979
P+ F C GY L+G H++C+ T W+ P+CIA CGG +
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 1980 -STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP-YH 2037
+ G I+SPGFPG+Y NNL C W + P G H+ F S + D L I+NG
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 2038 TSPMIGQFSGTDLP-AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP-PPFQ 2095
P+ + LP LLS+ + +D S G L Y+A++ +C +P +
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 2096 NGYMINSDYSVGQSVSFECYPGYIL-IGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQ 2154
N Y VG +V F C PGY L G ++ C + WN P C A C +T
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 2155 NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL 2214
G + SP +P+ Y +DCIW + V + ++ +L+ D + +DG D + L
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVL 659
Query: 2215 GVFSGNTALETAYSSTNQVLLKFHSDFSNG------GFFVLNFHAFQLKKCQPPPAVPQA 2268
G +SG + ++S V ++F SD GF + F + C P +P
Sbjct: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
Query: 2269 EMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTG 2328
+ G V YQC+PGY +VG+ +L C+ L + LP+C+ ++
Sbjct: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQW--DLTWSEDLPSCQRVTSCHD---- 773
Query: 2329 SSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPL 2388
PG+ +S+ S K + D L D +G SP
Sbjct: 774 ----------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAG-SP- 821
Query: 2389 LVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRT 2448
+WS D A + P L+ P +
Sbjct: 822 -----------------------KWS-DRAPK---CLLEQLKPCHGLSAPENGARSPEKQ 854
Query: 2449 AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
G+ +H+ C PGY + G ++ C P W P+C+A S
Sbjct: 855 LHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPICRAAS 899
Score = 212 bits (539), Expect = 6e-54
Identities = 172/604 (28%), Positives = 263/604 (43%), Gaps = 83/604 (13%)
Query: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIA 1450
+C+ P P G S G + F C GYQL+G +TC+ F W P CIA
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
Query: 1451 ACGGNL-TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIY 1509
ACGG + G I+SP +P Y C W ++ + L F+ ++ D L I
Sbjct: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
Query: 1510 EGEDSNSPLI-GSYQGSQAP-ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD 1567
G++ +P + SY+ P E + SSG F+ +D+S +G A+ ++ + C++
Sbjct: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
Query: 1568 P----GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSIT-CVIGADGKPSWDQVLPSC 1622
P GN + T + +G+T+ + CD GY + S I CV D P W++ P+C
Sbjct: 535 PFVKYGNFSSSTPT---YPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPAC 589
Query: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
A C G+ T S GVVLSPN+P Y GQ C++ + V ++ + + D+ +
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
Query: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASA----RGFHFVYQAVPRTS 1738
DG AR+L SG S L + + ++F + G S +GF + VPR +
Sbjct: 650 DGDDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPR-N 707
Query: 1739 DTQCSSVPEPRYGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
DT C +PE G + S E G++V ++C PGY + GS+ L CQ W++ +
Sbjct: 708 DT-CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDL 762
Query: 1797 PSC--VVPCS--GNFTQRRGTILSPGYPEPYGNNLNCIW-KIIVTEGSGIQIQVISFATE 1851
PSC V C G+ R I SP + P G + I + V GS I
Sbjct: 763 PSCQRVTSCHDPGDVEHSRRLISSPKF--PVGATVQYICDQGFVLMGSSI---------- 810
Query: 1852 QNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
L HD +P+ +S LL
Sbjct: 811 -----LTCHDR-QAGSPK---WSDRAPKCLLEQ--------------------------- 834
Query: 1912 GLAACQEPALPSNSIKIGDRYM--VNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSP 1969
L C + P N + ++ + + F C PGY L+G++ I C+PG W+ P P
Sbjct: 835 -LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPP 893
Query: 1970 LCIA 1973
+C A
Sbjct: 894 ICRA 897
Score = 199 bits (505), Expect = 5e-50
Identities = 153/556 (27%), Positives = 247/556 (44%), Gaps = 28/556 (5%)
Query: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGD 471
C N GP G + SP D + + P +++ + L G +T+TV
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVEG 302
Query: 472 AGKVGDT--RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCG 529
G + ++L G +I S ++Q L QS PG + + C
Sbjct: 303 LGGPDPLPLANQSFLLRGQ----VIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
Query: 530 DPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ--WSGNKPSCVFSCFF 587
P PAYG T +S G + F C ++L G R +TC Q W +P C+ +C
Sbjct: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
Query: 588 NF-TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKD-DG 645
A++G I+SP +P Y NN+ C WL+ + G R+HL F + D L +++ D
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
Query: 646 ISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIP 704
+ V ++ +P + L SSG +E +D S G + Y F Q C++P +
Sbjct: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
Query: 705 I-NGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHL 763
N + +G++V F CD G+ QGS I C+ + W+ T P C A C G +
Sbjct: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
Query: 764 TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSS 823
T S+GV+L P WP Y C W + + I + + D L DG ++
Sbjct: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
Query: 824 PLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSI----GFLIHYESVTLESDSCLD-PG 878
++G+Y G ++ L ++ + + F +D S + GF+IH+ V +D+C + P
Sbjct: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVP-RNDTCPELPE 715
Query: 879 IPVNGHRHGG--DFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG---- 932
IP NG + + + VT+ C PGY + L+C+ + W+ LPSC +
Sbjct: 716 IP-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
Query: 933 GYIQGKSGTVLSPGFP 948
G ++ + SP FP
Sbjct: 775 GDVEHSRRLISSPKFP 790
Score = 188 bits (478), Expect = 7e-47
Identities = 186/716 (25%), Positives = 292/716 (40%), Gaps = 86/716 (12%)
Query: 585 CFFNFTASSGIILSP---NYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
C +NF+ G + SP + P + G ++C + I PG + + + + + + + V
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNISLR-EGETVTV 300
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRG-FNITYTTFGQNECHD 700
+ G D L S + S H L FQS G G F+ Y + + CH
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
Query: 701 PGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCG 760
P P G G S FHC G+ + +G+ +TC L W S P C A CG
Sbjct: 360 PRRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACG 417
Query: 761 GHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGP 819
G + A++G I+ PG+PG Y ++L C W++EA G + + F++ + D L +R+G
Sbjct: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
Query: 820 -ASSSPLIGEYHGTQAP-QFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
+ P+ Y P + L+S+G ++ +TD+S ++ G + YE+ + C +P
Sbjct: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEA--FQQGHCYEP 535
Query: 878 GIPV-NGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLV-CERNH--QWNHALPSCDALCGG 933
+ N + + +TV FSCDPGYTL ++ C H QWN P+C A+C G
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSG 595
Query: 934 YIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSF 993
I +G VLSP +P+ Y +C W + V K + + + +L DG
Sbjct: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGD--VLTFYDG-- 651
Query: 994 SEPVARLTGSVLPHTIKAGLFGNFT-AQLRFISDFSIS----YEGFNITFSEYDL-EPCD 1047
+ AR+ G LF + ++F SD S +GF I F E + C
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 1048 D-PGVP-AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC--VA 1103
+ P +P + G +T+ C+ GY++ G++ L C WS LP C V
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVT 769
Query: 1104 EC--GASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
C V+ + + SP FP + C + F L L +
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFVLMGSSILTCH 814
Query: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDP 1221
D + S + W SD L L C
Sbjct: 815 DRQAGSPK----------------------W-------SDRAPKCLLE----QLKPCHGL 841
Query: 1222 GIPNYGYRIRDEG-HFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
P G R ++ H + +SC PGY + G ++ C+ G W P P C A
Sbjct: 842 SAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 187 bits (474), Expect = 2e-46
Identities = 179/652 (27%), Positives = 271/652 (41%), Gaps = 49/652 (7%)
Query: 1999 LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTT 2058
LDC + IS+ GYG I+ N S G P+ Q S + S T
Sbjct: 269 LDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQ-SFLLRGQVIRSPT 327
Query: 2059 HETLIHFYSDHSQNRQG-FKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPG 2117
H+ + F S G F YQAY L +C P G + + G S F C G
Sbjct: 328 HQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATG 386
Query: 2118 YILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWL 2176
Y L G LTC + W+ P C A CG + + G I SPGFP Y C WL
Sbjct: 387 YQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
Query: 2177 ITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL--GVFSGNTALETAYSSTNQVL 2234
+ P G ++++F + +D + + +G + +P + +E SS
Sbjct: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFF 506
Query: 2235 LKFHSDFSNGGF-FVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTL 2293
++ +D S L + AFQ C P V + + +G V++ C PGYTL
Sbjct: 507 VELSTDSSGAAAGMALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
Query: 2294 V-GTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSI 2352
G+ I+ C Q+ + P C A C + E+ T S+GV+LSP +P Y Q C W +
Sbjct: 566 EQGSIIIECVDPHDPQWNETEPACRAVC-SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGV 623
Query: 2353 KVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLR 2412
VE + I + + + D L +DG + +L SG + FTS ++ + ++
Sbjct: 624 HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQ 681
Query: 2413 WSTDHATSKKGFKIRYAAPY--------CSLTHPLKNGGILNRTAGAV-GSKVHYFCKPG 2463
+ +D TS G++ + + C + NG V G+ V Y C PG
Sbjct: 682 FQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPG 741
Query: 2464 YRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCGIPESPGNGS--FTGNEFTLDSKVVY 2520
Y++VG S C+ + W P CQ V SC P + + +F + + V Y
Sbjct: 742 YQVVGSSVLMCQWD----LTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQY 797
Query: 2521 ECHEGFKLESSQQATAVCQEDG--LWSNKG--------KPPTCKPVACPSIEAQLSEHVI 2570
C +GF L S T ++ G WS++ KP C ++ P A+ E
Sbjct: 798 ICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKP--CHGLSAPENGARSPEK-- 853
Query: 2571 WRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVIS 2622
L+ GA + SC+PGY L+G ++C + D P CR S
Sbjct: 854 ------QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 179 bits (454), Expect = 4e-44
Identities = 191/722 (26%), Positives = 286/722 (39%), Gaps = 80/722 (11%)
Query: 751 TVPRCEAPCGGHLTASSGVILPPGWPGYYKD-SLHCEWIIEAKPGHSIKITFDRFQT-EV 808
T + PC + + G + P D L C + I PG+ ++I E
Sbjct: 236 TTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG 295
Query: 809 NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIG-FLIHYESV 867
T+E GP PL + + Q + S + L F + + G F HY++
Sbjct: 296 ETVTVEGLGGP-DPLPLANQSFLLRG-QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY 353
Query: 868 TLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ--WNHALP 925
L SC P P G + F C GY L L C Q W+ P
Sbjct: 354 LL---SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEP 410
Query: 926 SCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDY 984
C A CGG I+ + G ++SPGFP Y N+L C W +E G+ + + F L D
Sbjct: 411 VCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR 470
Query: 985 LLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLE 1044
L+I + P + V I+ L + +D S + G + + +
Sbjct: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
Query: 1045 PCDDPGVPA--FSRRIGFHFGVGDSLTFSCFLGYRLE-GATKLTCLGGGRRVWSAPLPRC 1101
C +P V FS + VG ++ FSC GY LE G+ + C+ W+ P C
Sbjct: 531 HCYEPFVKYGNFSSSTPT-YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 1102 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
A C + + G +LSPN+P Y +CI+ + E K I L R ++ GD L Y
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
Query: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS--FDLVK-- 1217
DG D ++R LG ++ + S ++ + ++F ++ + G+Q + F++ +
Sbjct: 650 DGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 1218 -CED-PGIPNYGYRIRDEGHFTD-TVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
C + P IPN G++ + TVV Y C PGY + GS+ L C W + LPSC
Sbjct: 709 TCPELPEIPN-GWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
Query: 1275 --IAECGGQIHAATSGRILS-PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHD 1331
+ C S R++S P +P C D G + M
Sbjct: 766 QRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----------MGSS 809
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
IL D S +WS A P+ +
Sbjct: 810 ILTCHDRQAGSP----KWSDRA-PKCLLEQLKP--------------------------- 837
Query: 1392 CNDPGMPQNGTRYGDSR--EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI 1449
C+ P+NG R + + AG T+ F C PGY L+GQA I CV + W PP C
Sbjct: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVP-GHPSHWSDPPPICR 896
Query: 1450 AA 1451
AA
Sbjct: 897 AA 898
Score = 164 bits (416), Expect = 1e-39
Identities = 149/567 (26%), Positives = 239/567 (42%), Gaps = 46/567 (8%)
Query: 1452 CGGNLTGPAGVILSP-NYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYE 1510
C N +GP G + SP + P G +C + + V P + + + ++ ++ E
Sbjct: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
Query: 1511 GEDSNSPL-IGSYQGSQAPERIESSGNSLFLAFRS-DASVGLSGFAIEFKEKPREACFDP 1568
G PL + + + I S + L F+S G F ++ +C P
Sbjct: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
Query: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGG 1628
G T G + + C +GY++ +TC+ +P WD P C A CGG
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
Query: 1629 QY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE------L 1681
+ G ++SP +P NY+ C + + P+ GQ + LAE +
Sbjct: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLII 473
Query: 1682 FDGTHAQARLLSSLSGSHSGETLP----LATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
+G + +A + S+ E LP L++ + S S +A G Y+A +
Sbjct: 474 RNGDNVEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
Query: 1738 SDTQCSSVPEPRYGRRIGSE--FSAGSIVRFECNPGYLL-QGSTALHCQSVPNALAQWND 1794
+ P +YG S + G+ V F C+PGY L QGS + C + QWN+
Sbjct: 531 HCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNE 584
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
T P+C CSG T G +LSP +PEPYG +CIW + V E I + +
Sbjct: 585 TEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG- 643
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE-----YK 1909
D L +DG D+TA LG +SG L ++ + + FQSD + G+ ++
Sbjct: 644 DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 703
Query: 1910 TVGLAACQE-PALPSNSIKIGDRYMVN-DVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1967
C E P +P+ +V+ V+++QC PGY + G S + C + P
Sbjct: 704 VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLP 763
Query: 1968 SPLCIATC--GGTLSTLGGVILSPGFP 1992
S + +C G + +I SP FP
Sbjct: 764 SCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 158 bits (400), Expect = 8e-38
Identities = 170/672 (25%), Positives = 254/672 (37%), Gaps = 98/672 (14%)
Query: 887 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSP- 945
G GI+ T+T S G D+E C G G++ SP
Sbjct: 203 GAGIGIQGTITSSTASG---DDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPT 259
Query: 946 GFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVL 1005
L+C + I V G GV++ L + G P+A + +
Sbjct: 260 DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLR 319
Query: 1006 PHTIKAGLFGNFTAQLRFISDFSISYEG-FNITFSEYDLEPCDDPGVPAFSRRIGFHFGV 1064
I++ A LRF S + G F+ + Y L C P PA+
Sbjct: 320 GQVIRSP---THQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
Query: 1065 GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPS 1123
G S F C GY+L+GA LTCL + W + P C+A CG ++ G ++SP FP
Sbjct: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
Query: 1124 NYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT-LKVYDGKDSSSRPLGTFTKNELLGL 1182
NY NN C + +E G+ +HL L E D L + +G + + P+ + E L +
Sbjct: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Query: 1183 I-LNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVV 1241
L S+ H ++E +T+ S G L Y +F C +P + + + T V
Sbjct: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTV 555
Query: 1242 LYSCNPGYAMH-GSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYD 1300
+SC+PGY + GS + C+ W++ P+C A C G+I ++G +LSP +P PY
Sbjct: 556 EFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI-TDSAGVVLSPNWPEPYG 614
Query: 1301 NNLHCTWIIEADPGKTISL----------------------------------HFIVFDT 1326
C W + + K I L HF +F T
Sbjct: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLF-T 673
Query: 1327 EMAHDILKVWDGPVDSDILLKE------------------------WSGSALPEDIHSTF 1362
MA ++ P S + ++ W + PE +H T
Sbjct: 674 SMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTV 733
Query: 1363 ------------NSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSRE- 1409
S L D S+ S Q TS C+DPG ++ R S +
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS----CHDPGDVEHSRRLISSPKF 789
Query: 1410 -AGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTC----IAACGGNLTGPAGVI 1463
G TV + CD G+ L G + +TC W P C + C G L+ P
Sbjct: 790 PVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG-LSAPENGA 848
Query: 1464 LSPNYPQPYPPG 1475
SP Q +P G
Sbjct: 849 RSPE-KQLHPAG 859
Score = 155 bits (391), Expect = 9e-37
Identities = 182/749 (24%), Positives = 289/749 (38%), Gaps = 118/749 (15%)
Query: 206 GACGGTLRGTSSSISSP-HFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
G C G S+ SP S + DC + I PG + + + L EG + + +
Sbjct: 242 GPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTV 300
Query: 265 SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKM 324
G P P P+ + LR H+ A+ +S
Sbjct: 301 EGLGGPD--------PLPLANQSFLLRGQVIRSPTHQA-----------ALRFQSLPPPA 341
Query: 325 LPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQG 384
P H + L C P P G + G + +F C Y L+G
Sbjct: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSL-HPGGSARFHCATGYQLKG 391
Query: 385 SKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS-GVITSPNYPVQYEDNAHCVWVIT 443
++ +TC T+ W P+C A CG +R + G I SP +P Y +N C W++
Sbjct: 392 ARHLTCLNATQPF--WDSKEPVCIA-ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLE 448
Query: 444 TTDPDKVIKLAFEEFELERGYDTLTV--GD---AGKVGDTRSVLYVLTGSSVPDLIVSMS 498
+ + + L FE+ L D L + GD A V D+ V Y+ ++S
Sbjct: 449 APEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEG-----LLSSG 502
Query: 499 NQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLH--GDTLTFECPA 556
++ L +D S + G Y+ ++G C +P + YG + S+ + G T+ F C
Sbjct: 503 KHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK-YGNFSSSTPTYPVGTTVEFSCDP 561
Query: 557 AFELV-GERVITC--QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVW 613
+ L G +I C + QW+ +P+C C T S+G++LSPN+PE YG +C+W
Sbjct: 562 GYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIW 621
Query: 614 LIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRL 673
+ E RI L + P D L D VLG +SG +L +S V +
Sbjct: 622 GVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTI 680
Query: 674 EFQSDHSTT----GRGFNITYTTFGQNE-CHD-PGIPINGRRFGDR--FLLGSSVSFHCD 725
+FQSD T+ +GF I + +N+ C + P IP NG + + + G+ V++ C
Sbjct: 681 QFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQCY 739
Query: 726 DGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHC 785
G+ + GS + C ++ WS +P C+ H PG D H
Sbjct: 740 PGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCH---------DPG------DVEHS 780
Query: 786 EWIIEAKP---GHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTG 842
+I + G +++ D+ + L D A S +AP+ L+
Sbjct: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK-----WSDRAPKCLLEQL 835
Query: 843 NFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDP 902
+ L +N S +H +T+ FSC P
Sbjct: 836 KPCHGLSAPENGARSPEKQLHPAG---------------------------ATIHFSCAP 868
Query: 903 GYTLSDDEPLVCERNH--QWNHALPSCDA 929
GY L + C H W+ P C A
Sbjct: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
Score = 135 bits (340), Expect = 7e-31
Identities = 130/478 (27%), Positives = 194/478 (40%), Gaps = 62/478 (12%)
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+C P G + T + G R+ C GY L+G LTC+ + WD P C
Sbjct: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNA--TQPFWDSKEPVCI 413
Query: 204 AEGACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFL 262
A ACGG +R T+ I SP FP Y NN C W + A G + L F L E D L
Sbjct: 414 A--ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
Query: 263 EI---SGTEAPSIWLTGMNLPSPV---ISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
I EAP ++ + P+ +SS + ++DS+ G +++
Sbjct: 472 IIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE------ 525
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSC 376
A C +P + + + VG V+FSC
Sbjct: 526 --------------------------AFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSC 559
Query: 377 EDNYVL-QGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
+ Y L QGS I C V W++ P CRA C + +GV+ SPN+P Y
Sbjct: 560 DPGYTLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRG 616
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
C+W + + DK I L + G D LT D + T VL +G +
Sbjct: 617 QDCIWGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLF 672
Query: 496 SMSNQMWLHLQSDDSIG----SPGFKAVYQEIEKGG-CGD-PGIP-AYGKRTGSSFLHGD 548
+ + + QSD GF + E+ + C + P IP + + +HG
Sbjct: 673 TSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGT 732
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC--VFSCF--FNFTASSGIILSPNYP 602
+T++C +++VG V+ CQ + WS + PSC V SC + S +I SP +P
Sbjct: 733 VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Score = 116 bits (291), Expect = 3e-25
Identities = 107/422 (25%), Positives = 163/422 (38%), Gaps = 53/422 (12%)
Query: 32 CGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYD 90
CGG+++ G I SPGFP Y N C W++ E R+ L F +L ED D L + +
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 91 GQ-----PQQGNLKVRLSGFQLP-SSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
G P + +V LP ++S+G + +TD + +A G YE
Sbjct: 476 GDNVEAPPVYDSYEVE----YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGH 531
Query: 145 CGNPGEILKGVLHGT-RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
C P T + +G + +SC PGY LE +I+ V P + W+ P CR
Sbjct: 532 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDP-HDPQWNETEPACR 590
Query: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
A C G + ++ + SP++P Y DC W + E I L ++ G
Sbjct: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF 648
Query: 264 ISGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
G + + L +G + +S + + F SD G+ F + ++
Sbjct: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
Query: 321 GVKMLPSKDGSHKNS--------------------------VLSQGGVALVSDM------ 348
LP K+ ++ Q + D+
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 349 --CPDPGIPENGRR-AGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRP 405
C DPG E+ RR S VGA VQ+ C+ +VL GS +TC WSD P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 406 IC 407
C
Sbjct: 829 KC 830
Score = 105 bits (261), Expect = 1e-21
Identities = 99/371 (26%), Positives = 158/371 (42%), Gaps = 24/371 (6%)
Query: 2146 PCGYNVTSQNGTIYSP-GFPDEYPILKDCIWLITVPPGHGVYI---NFTLLQTEAVNDYI 2201
PC +N + G++ SP + DC + I+V PG+GV I N +L + E V +
Sbjct: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
Query: 2202 AVWDGPDQN--SPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH-AFQLKK 2258
GPD + Q + G + S T+Q L+F S G +FH L
Sbjct: 301 EGLGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS 356
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
C P ++ G ++ C GY L G LTC ++Q ++ P C A
Sbjct: 357 CHFPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA 414
Query: 2319 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEV 2378
C +R ++G I+SPG+PGNY N+ TC W ++ + + + + D L +
Sbjct: 415 AC-GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
Query: 2379 FDGSSGQS-PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCS 2434
+G + ++ P+ + S ++ STD + + G +RY A +C
Sbjct: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
Query: 2435 LTHPLKNGGILNRT-AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQA 2493
+K G + T VG+ V + C PGY + S +P QW+ P C+A
Sbjct: 534 EPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRA 591
Query: 2494 VSCG-IPESPG 2503
V G I +S G
Sbjct: 592 VCSGEITDSAG 602
Score = 105 bits (261), Expect = 1e-21
Identities = 157/651 (24%), Positives = 236/651 (36%), Gaps = 111/651 (17%)
Query: 2348 CSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSN 2407
C + I V P Y + I V S ++ + + V +G G PL + S ++
Sbjct: 271 CFFYISVYPGYGVEIKVQNI-SLREGETVTV-EGLGGPDPLPLANQSFLLRGQVIRSPTH 328
Query: 2408 QLYLRWSTDHATSKKG-FKIRYAAPYCSLTHPLKNG-GILNRTAGAVGSKVHYFCKPGYR 2465
Q LR+ + + G F Y A S P + G + T+ G + C GY+
Sbjct: 329 QAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ 388
Query: 2466 MVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECH-- 2523
+ G + TC WDS P+C A G+ + G F + CH
Sbjct: 389 LKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
Query: 2524 ----EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
EG +L + ++ ++D + P S E + + + G
Sbjct: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE------YLPIEG--- 497
Query: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT 2639
LLS +++E L + + + + C F GN +
Sbjct: 498 ------LLSSGKHFFVE---LSTDSSGAAAGMALRYEAFQQGHCYE-PFVKYGNFSSSTP 547
Query: 2640 VY--GATAIFTCNTGYTLV-GSHVRECLA--NGLWSGSETRCLAGHCGS----------- 2683
Y G T F+C+ GYTL GS + EC+ + W+ +E C A G
Sbjct: 548 TYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSP 607
Query: 2684 --PDPIVNG-------HISGDGFSYRDTVVYQCNPG------------------------ 2710
P+P G H+ D D V + PG
Sbjct: 608 NWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
Query: 2711 -FRLVGTSVRICLQDHKWSGQTPVC-----------VPI--TCGHPGNPAHGFTNGSEFN 2756
F+L + + +Q G + + VP TC +G+ + S+
Sbjct: 668 HFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPE 727
Query: 2757 L--NDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC-RVVNCSDPGFVENAIRHGQQN 2813
L VV + C GY + G S C+ + WS LP+C RV +C DPG VE++ R
Sbjct: 728 LVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISS- 786
Query: 2814 FPESFEYGMSILYHCKKGFYLLGSSALTC----MANGLWDRSLPKCLAIS---CGHPGVP 2866
F G ++ Y C +GF L+GSS LTC + W PKCL C P
Sbjct: 787 --PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAP 844
Query: 2867 ANAVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVC--QEDSHWSGALPHC 2913
N + E L GA +H+SC L G + C SHWS P C
Sbjct: 845 ENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 87.0 bits (214), Expect = 3e-16
Identities = 127/550 (23%), Positives = 185/550 (33%), Gaps = 146/550 (26%)
Query: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL--LNGSWSGLQPVCEAVS 2978
C P PA+G RF C G+QL+G+ TCL W +PVC A +
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA-A 415
Query: 2979 CG------------NPGTP---------------------------------------TN 2987
CG +PG P N
Sbjct: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
Query: 2988 GMIVSSDGILFSSSVIYACWEGYKTSG---LMTRHCTANGTWTGTAPDCTIIS---CGDP 3041
G V + + S V Y EG +SG + ++G G A C +P
Sbjct: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
Query: 3042 GTLANGIQFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTK--DGRWNPSKPVCKA--- 3095
T + TV + C+PGY +E S I C D +WN ++P C+A
Sbjct: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ-GSIIIECVDPHDPQWNETEPACRAVCS 594
Query: 3096 ---------VLCPQPPPVQNGTVEGSDFRWGSSIS-------------------YSCMDG 3127
VL P P G D WG + + DG
Sbjct: 595 GEITDSAGVVLSPNWPEPYG---RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
Query: 3128 YQLSHSAILSCEG-RGVWK--GEIPQCLPVFCGDPGIPAEGRLSG--------------- 3169
L+ + G R +K + F DPG G G
Sbjct: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
Query: 3170 --------------KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHN 3215
+ + V +QC + +VGSS +CQ D TWS P+C
Sbjct: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
Query: 3216 TCPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC----LANLTWSGIQTE 3270
+C DPG H SS + VG+TV + C +G+ + GS+ TC + WS +
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3271 CIP------HACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKA-DMK 3323
C+ H PE A + + L G T+ ++C PG+ L G + +
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEK--QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 3324 WTGKSPVCKS 3333
W+ P+C++
Sbjct: 888 WSDPPPICRA 897
Score = 80.5 bits (197), Expect = 3e-14
Identities = 56/207 (27%), Positives = 88/207 (42%), Gaps = 17/207 (8%)
Query: 3098 CPQPPPVQNGTVEGS--DFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV- 3154
CP+ P + NG S + G+ ++Y C GYQ+ S++L C+ W ++P C V
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
Query: 3155 FCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQ----ADGTWSGIQPT 3208
C DPG R +S F + V + C F+L+GSS C WS P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 3209 CIDPAHNTCPDPGTPHFGIQNSSRG-YEVGSTVFFRCRKGYHIQGSTTRTCLAN--LTWS 3265
C+ C P G ++ + + G+T+ F C GY ++G + C+ WS
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
Query: 3266 GIQTECIPHACRQPETPAHADVRAIDL 3292
P CR + R++D+
Sbjct: 890 D-----PPPICRAASLDGFYNSRSLDV 911
Score = 76.3 bits (186), Expect = 5e-13
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT-CGHPGNPAHG--FTNGSEFNLND 2759
V YQC PG+++VG+SV +C D WS P C +T C PG+ H + +F +
Sbjct: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGA 793
Query: 2760 VVNFTCNTGYLLQGVSRAQCR----SNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQ 2812
V + C+ G++L G S C + +WS P C ++ C EN R ++
Sbjct: 794 TVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEK 853
Query: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRSLPKCLAIS 2859
+ G +I + C G+ L G +++ C+ W P C A S
Sbjct: 854 QLHPA---GATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
Score = 71.6 bits (174), Expect = 1e-11
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 2622 SCGSLSFPPNGNKIGTLT--VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC-LA 2678
+C L PNG K + V+G + C GY +VGS V C + WS C
Sbjct: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 2679 GHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC----LQDHKWSGQTP 2732
C P + + IS F TV Y C+ GF L+G+S+ C KWS + P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 2733 VCVPITCGHPGNPAHGFT---NGS---EFNLND---VVNFTCNTGYLLQGVSRAQCRSN- 2782
C+ P HG + NG+ E L+ ++F+C GY+L+G + +C
Sbjct: 829 KCLL----EQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGH 884
Query: 2783 -GQWSSPLPTCRVVN 2796
WS P P CR +
Sbjct: 885 PSHWSDPPPICRAAS 899
Score = 47.4 bits (111), Expect = 3e-04
Identities = 49/158 (31%), Positives = 66/158 (41%), Gaps = 37/158 (23%)
Query: 698 CHDPGIPINGRRF--GDRFLLGSSVSFHCDDGFVKTQGSESITC-ILQDGNVVWSSTVPR 754
CHDPG + RR +F +G++V + CD GFV GS +TC Q G+ WS P+
Sbjct: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV-LMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 755 C----EAPCGGHLTASSGV------ILPPG-------WPGYYKDSLHCEWIIEAKPGHSI 797
C PC G +G + P G PGY L + I+ PGH
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYV---LKGQASIKCVPGHPS 886
Query: 798 ----------KITFDRFQTEVNYDTLEVRDGPASSSPL 825
+ D F N +L+V PA+SS L
Sbjct: 887 HWSDPPPICRAASLDGF---YNSRSLDVAKAPAASSTL 921
Score = 47.0 bits (110), Expect = 3e-04
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 164 GDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACG 209
G I +SC PGY+L+G A + C+ PG+ + W P P CRA G
Sbjct: 859 GATIHFSCAPGYVLKGQASIKCV--PGHPSHWSDPPPICRAASLDG 902
Score = 41.6 bits (96), Expect = 0.014
Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 144 TCGNPGEI--LKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
+C +PG++ + ++ +F +G ++Y C G++L G +ILTC W AP
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 202 CRAE 205
C E
Sbjct: 830 CLLE 833
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 228 bits (581), Expect = 8e-59
Identities = 183/647 (28%), Positives = 291/647 (44%), Gaps = 125/647 (19%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G+ + G I SP YP+ Y + CIW+I V+EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY-KTVGLAACQ 1917
+ DG ++ +G + G P + STS++L+L F SD S+ AGF + + K V C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD--ECS 552
Query: 1918 EPALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC 1975
P ++ +N + S++C +PGY L P R C A C
Sbjct: 553 RPNRGGC-----EQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAAC 591
Query: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEI 2031
GG L+ L G I SPG+P YP N +C W++ P Y +QF F TE N +DF+E+
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
++G S + G+F G++ P + S + + F SD++ +++GFK A+ + C
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK-AHFFSDKDECSK- 709
Query: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV 2151
NG + S +C G++L + +H +A C + V
Sbjct: 710 ---DNGGCQQDCVNTFGSYECQCRSGFVLHDN-----KHDCK----------EAGCDHKV 751
Query: 2152 TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL----QTEAVNDYIAVWDGP 2207
TS +GTI SP +PD+YP K+C W I+ PGH V + F + Q E D++ V+DG
Sbjct: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
Query: 2208 DQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQ 2267
D +P LG F G+ E ++ +++ L+F+SD ++ Q K Q A
Sbjct: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD-----------NSVQRKGFQASHAT-- 858
Query: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRT 2327
E G V+ D+ T L S QF +
Sbjct: 859 ----------ECGGQVR-----------ADVKTKDLYSHAQFGDN--------------- 882
Query: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGSS 2383
YPG C W I E Y + + TF+ E++ +D +E+FDG
Sbjct: 883 ---------NYPGGV----DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD 929
Query: 2384 GQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
+P L G+ + + S + + +++ +D +KKGF +RY +
Sbjct: 930 STAPRLGRYCGSGPPEEVY-SAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 199 bits (506), Expect = 4e-50
Identities = 184/672 (27%), Positives = 271/672 (40%), Gaps = 126/672 (18%)
Query: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Y + G K QR + + R + + CG L+ +G +SP YP Y + HCV
Sbjct: 290 YEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCV 349
Query: 440 WVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
W I+ T +K+I L F +L R YD + V D + GS +P+ IV
Sbjct: 350 WRISVTPGEKII-LNFTSLDLYRSRLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIV 406
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
S +++W+ +S + GF AVY+ I CG YG
Sbjct: 407 STDSRLWVEFRSSSNWVGKGFFAVYEAI----CGGDVKKDYGH----------------- 445
Query: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Q N +PS V C + S G
Sbjct: 446 ------------IQSPNYPDDYRPSKV--CIWRIQVSEGF-------------------- 471
Query: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
+ L F F++E +D+L V+D T++G + G E P + S+ +
Sbjct: 472 ------HVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRL 525
Query: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
L+F SD S GF + + +EC P R G C+ + T
Sbjct: 526 WLKFVSDGSINKAGFAVNFFK-EVDECSRP------NRGG------------CEQRCLNT 566
Query: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
GS +C D + RCEA CGG LT +G I PGWP Y + +C W + A
Sbjct: 567 LGSYKCSC---DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
Query: 792 KPGHSIKITFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYL 847
+ I + FD F+TE N YD +EVR G + S L G++ G++ P+ + S N M +
Sbjct: 624 PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRV 683
Query: 848 LFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLS 907
F +DN+ S GF H+ S + D C NG + C G+ L
Sbjct: 684 EFKSDNTVSKKGFKAHFFS---DKDECSKD----NGGCQQDCVNTFGSYECQCRSGFVLH 736
Query: 908 DDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGK 967
D++ H +A C + SGT+ SP +PD YP+ CTW I + G
Sbjct: 737 DNK-------HDCK------EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGH 783
Query: 968 GVQMIFHTFHLES----SHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLR 1022
V++ F +ES ++D+L + + PV R GS P + A F LR
Sbjct: 784 RVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMF---LR 840
Query: 1023 FISDFSISYEGF 1034
F SD S+ +GF
Sbjct: 841 FYSDNSVQRKGF 852
Score = 196 bits (497), Expect = 5e-49
Identities = 145/466 (31%), Positives = 218/466 (46%), Gaps = 61/466 (13%)
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT----- 1157
A CG VK + G + SPN+P +Y + CI++I+ G + L +SF++ D+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
L+V DG SS +G + E I STS+ LWL+F ++GS GF + + ++ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDI-KSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDE 550
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLY--SCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
C P R E +T+ Y SC+PGY L+ D+R C
Sbjct: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYE---------LAPDKR-------RCE 588
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
A CGG + +G I SPG+P Y N +C W + A ISL F F+TE +D
Sbjct: 589 AACGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
++V G L ++ GS PE I S +N++ ++F SD +SK GF F +
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSD---- 703
Query: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
D NG D + QC G+ L K C + A
Sbjct: 704 -KDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDN-KHDCKE---------------AG 746
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLH 1507
C +T +G I SPN+P YP KEC W + P + L F ++E +YD L
Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
Query: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
+++G D+ +P++G + GS+ PE + ++G+ +FL F SD SV GF
Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF 852
Score = 190 bits (483), Expect = 2e-47
Identities = 139/480 (28%), Positives = 219/480 (45%), Gaps = 73/480 (15%)
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDF 1505
A CGG++ G I SPNYP Y P K C WR++V+ F + L F+SF +E +YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1506 LHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREAC 1565
L + +G +S LIG Y G + P+ I+S+ + L+L F SD S+ +GFA+ F ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1566 FDPGNIMNGTRVGTDFKLGSTI-TYQ--CDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
P R G + + +T+ +Y+ CD GY++ C
Sbjct: 552 SRP------NRGGCEQRCLNTLGSYKCSCDPGYELAPDKR------------------RC 587
Query: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDL---- 1678
A CGG T G + SP +P Y + C++ + P ++ + QF +F+T ND+
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1679 -AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF--HFVYQAVP 1735
E+ G A ++L GS E + + N + + F + + S +GF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHFF----- 701
Query: 1736 RTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDT 1795
+ +CS + G + + GS +C G++L +D
Sbjct: 702 -SDKDECS---KDNGGCQQDCVNTFGS-YECQCRSGFVL------------------HDN 738
Query: 1796 IPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN- 1853
C C T GTI SP +P+ Y + C W I T G +++ + E
Sbjct: 739 KHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP 798
Query: 1854 ---WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1910
+D LE+ DG D AP LG F G+ P + +T ++++L F SD SV GF + T
Sbjct: 799 ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
Score = 187 bits (474), Expect = 2e-46
Identities = 163/635 (25%), Positives = 255/635 (40%), Gaps = 124/635 (19%)
Query: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
A CGG G + SPNYP +Y ++C++ I V + F V F F+ + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHF-VYQAVPRT 1737
E+ DG + L+ G + + +TS+++ L+F + + GF ++ V
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1738 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
S E R +GS + C+PGY L
Sbjct: 552 SRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR------------------ 585
Query: 1798 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1853
C C G T+ G+I SPG+P+ Y N NCIW+++ I +Q F TE N
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 1854 WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGL 1913
+D +E+ G + G F G+ P ++ S N + + F+SD +V+ GF +
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF----- 700
Query: 1914 AACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIA 1973
+ ++ N D QC G+ L H C A
Sbjct: 701 FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKH-DCKE--------------A 745
Query: 1974 TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFL 2029
C +++ G I SP +P YP+ +CTW IS G+ + F+ E+ +D L
Sbjct: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 2030 EIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCP 2089
E+ +G +P++G+F G+ P +L+T + FYSD+S R+GF QA C
Sbjct: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGF----QASHATEC- 860
Query: 2090 DPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGY 2149
G + +D S Q G N NYP
Sbjct: 861 -------GGQVRADVKTKDLYSH---------------AQFGDN---NYP---------- 885
Query: 2150 NVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLL----QTEAVNDYIAVWD 2205
G + DC W+I G+GV + F +T+ DY+ ++D
Sbjct: 886 ------GGV-------------DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD 926
Query: 2206 GPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
G D +P+LG + G+ E YS+ + VL+KFHSD
Sbjct: 927 GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSD 961
Score = 186 bits (472), Expect = 4e-46
Identities = 179/681 (26%), Positives = 267/681 (39%), Gaps = 160/681 (23%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CGG V+ G I+SP +P Y C W I E + L+F +F +E +D L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG + L R G++ P I ST S L L F +D +++ GF A+ C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-AVNFFKEVDECSR 553
Query: 148 PGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGA 207
P +G N + SC PGY L +P R E A
Sbjct: 554 PN---RGGCEQRCLNTLGSYKCSCDPGYEL----------APDKR----------RCEAA 590
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263
CGG L + SI+SP +P EY N +C W ++A I+L F F+ E YDF+E
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 264 I-SGTEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319
+ SG A S G P + S N +R+ F SD+ +KGF A F
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF---------- 700
Query: 320 RGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDN 379
KD K++ GG D + + C
Sbjct: 701 -----FSDKDECSKDN----GGCQ-------------------QDCVNTFGSYECQCRSG 732
Query: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+VL D++ C+ C + SG ITSPN+P +Y C
Sbjct: 733 FVLH------------------DNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECT 774
Query: 440 WVITTTDPDKVIKLAFEEFELER----GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
W I++T P +KL F E ++E YD L V D VL GS P+ ++
Sbjct: 775 WAISST-PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA--KAPVLGRFCGSKKPEPVL 831
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
+ ++M+L SD+S+ G +Q CG G +T + H
Sbjct: 832 ATGSRMFLRFYSDNSVQRKG----FQASHATECG--GQVRADVKTKDLYSHA-------- 877
Query: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Q+ N NYP ++C W+I
Sbjct: 878 -----------------QFGDN----------------------NYP----GGVDCEWVI 894
Query: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
++E G + L+F F+VE + +D++ + D S LG + G+ P ++ S+G V
Sbjct: 895 VAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSV 954
Query: 672 RLEFQSDHSTTGRGFNITYTT 692
++F SD + T +GF++ YT+
Sbjct: 955 LVKFHSDDTITKKGFHLRYTS 975
Score = 182 bits (462), Expect = 5e-45
Identities = 165/648 (25%), Positives = 273/648 (42%), Gaps = 124/648 (19%)
Query: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SHD 983
+A+CGG ++ G + SP +PD Y S C W I+VS G V + F +F +E ++D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 984 YLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
YL + + S S + R G P IK+ + L+F+SD SI+ GF + F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKST---SSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
++ C P +R G S SC GY L + RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK--- 1159
A CG + G++ SP +P Y N CI+++ I L+ F+ D K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1160 --VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
V G + S+ G F +E ++ S N++ +EF ++ + + +GF+ + S D +
Sbjct: 649 VEVRSGLTADSKLHGKFCGSE-KPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDE 706
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAE 1277
C + G + C G+ +H N C A
Sbjct: 707 CSKDNGGCQQDCVNTFGSYE-----CQCRSGFVLH-DNKHDCKE--------------AG 746
Query: 1278 CGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD----TEMAHDIL 1333
C ++ +TSG I SP +P Y + CTW I + PG + L F+ D E A+D L
Sbjct: 747 CDHKV-TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 1334 KVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCN 1393
+V+DG +L + GS PE + +T + + L+F SD + + GF +T
Sbjct: 806 EVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT------- 858
Query: 1394 DPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACG 1453
+C G Q++ K + + +F G
Sbjct: 859 -----------------------EC--GGQVRADVKTKDLYSHAQF-------------G 880
Query: 1454 GNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLHIY 1509
N NYP G +C+W + + + L+F++F +E YD++ ++
Sbjct: 881 DN-----------NYP----GGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELF 925
Query: 1510 EGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
+G DS +P +G Y GS PE + S+G+S+ + F SD ++ GF + +
Sbjct: 926 DGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 180 bits (457), Expect = 2e-44
Identities = 146/469 (31%), Positives = 214/469 (45%), Gaps = 66/469 (14%)
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
A CGG + G I SP YP Y + C W I+ G + L F F+ E A+D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
L+V DG +S L+ + G P+DI ST + L L+F SD I+K+GF++ F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE- 550
Query: 1392 CNDPGMPQNGTRYGDSREAGDTV---TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C+ P R G + +T+ CDPGY+L PD C
Sbjct: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYELA-----------------PDKRRC 587
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YD 1504
AACGG LT G I SP +P+ YPP K C W++ + I+L F F E + YD
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREA 1564
F+ + G ++S L G + GS+ PE I S N++ + F+SD +V GF F E
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
Query: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
D G G + GS QC SG+ +L + C A
Sbjct: 708 SKDNG----GCQQDCVNTFGS-YECQCRSGF-VLHDNKHDCK----------------EA 745
Query: 1625 PCGGQYTGSEGVVLSPNYPHNYTAGQICLYSIT------VPKEFVVFGQFAYFQTALNDL 1678
C + T + G + SPN+P Y + + C ++I+ V F+ + + A + L
Sbjct: 746 GCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHL 805
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1727
E+FDG A+A +L GS E + LAT +++ LRF + + +GF
Sbjct: 806 -EVFDGRDAKAPVLGRFCGSKKPEPV-LATGSRMFLRFYSDNSVQRKGF 852
Score = 167 bits (424), Expect = 1e-40
Identities = 133/472 (28%), Positives = 210/472 (44%), Gaps = 62/472 (13%)
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
A CGG + G I SP +P Y + C WRI + G+ + F +F E + +D+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
LE+++G +S +IG++ G + P + ST+ + F SD S N+ GF + + E+ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
P G + S C PGY L RC+A CG
Sbjct: 552 SRP---NRGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEAACG 592
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVW 2204
+T NG+I SPG+P EYP K+CIW + P + + + F +TE + D++ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLK-KCQP 2261
G +S G F G+ E S N + ++F SD S GF H F K +C
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF---KAHFFSDKDECSK 709
Query: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCP 2321
Q + + +E QC G+ L + CK EA C
Sbjct: 710 DNGGCQQDCVNTFGSYEC------QCRSGFVL-HDNKHDCK--------------EAGC- 747
Query: 2322 ANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALE 2377
+ T +SG I SP +P Y + + C+W+I P + + + E Q +D LE
Sbjct: 748 -DHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
VFDG ++P+L G+ + + S +++LR+ +D++ +KGF+ +A
Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGS-RMFLRFYSDNSVQRKGFQASHA 857
Score = 160 bits (405), Expect = 2e-38
Identities = 139/525 (26%), Positives = 217/525 (41%), Gaps = 107/525 (20%)
Query: 191 NGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF 250
+ ++W F E CGG ++ I SP++P +Y + C W I G + L F
Sbjct: 418 SSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF 477
Query: 251 TDFQLEE----GYDFLEISGTEAPSIWLTGM----NLPSPVISSKNWLRLHFTSDSNHRR 302
F++E YD+LE+ + S L G P + S+ + L L F SD + +
Sbjct: 478 QSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINK 537
Query: 303 KGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAG 362
GF F K ++ SR P++ G + + + G
Sbjct: 538 AGFAVNFF--KEVDECSR-----PNRGGCEQRCLNTLG---------------------- 568
Query: 363 SDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV 422
+ + SC+ Y L K C A CG L +G
Sbjct: 569 --------SYKCSCDPGYELAPDKRR------------------CEA-ACGGFLTKLNGS 601
Query: 423 ITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDT 478
ITSP +P +Y N +C+W + + I L F+ FE E YD + V +G D+
Sbjct: 602 ITSPGWPKEYPPNKNCIWQLVAPTQYR-ISLQFDFFETEGNDVCKYDFVEVR-SGLTADS 659
Query: 479 RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVY----QEIEK--GGCGDPG 532
+ + GS P++I S N M + +SD+++ GFKA + E K GGC
Sbjct: 660 K-LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDC 718
Query: 533 IPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFS-CFFNFTA 591
+ +G ++EC C+ NK C + C T+
Sbjct: 719 VNTFG-------------SYECQ------------CRSGFVLHDNKHDCKEAGCDHKVTS 753
Query: 592 SSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGIS 647
+SG I SPN+P++Y + C W I S PG R+ L F + D+E Q +D L V D +
Sbjct: 754 TSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
Query: 648 DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
VLG F G++ P + ++G + L F SD+S +GF ++ T
Sbjct: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
Score = 124 bits (312), Expect = 1e-27
Identities = 130/512 (25%), Positives = 200/512 (39%), Gaps = 110/512 (21%)
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLE 2030
CG TL G SP +P Y ++ C WRIS+ G + F + + +D++E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPD 2090
+++G + +P+ G+F G+ LP ++ST + F S + +GF Y+A C
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----C-- 435
Query: 2091 PPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
G + DY QS NYP
Sbjct: 436 ------GGDVKKDYGHIQSP--------------------------NYP----------- 452
Query: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAVWDG 2206
D+Y K CIW I V G V + F + E DY+ V DG
Sbjct: 453 --------------DDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG 498
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
++S +G + G + S+++++ LKF SD S N F +NF ++ +C P
Sbjct: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSRPNRG 557
Query: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
+ +G + K C PGY L CEA C
Sbjct: 558 GCEQRCLN----TLGSY-KCSCDPGYELA----------------PDKRRCEAAC--GGF 594
Query: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----QFDALEVFDG 2381
T +G I SPG+P Y ++ C W + Y I++ D F++E ++D +EV G
Sbjct: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
Query: 2382 SSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA--PYCSLTHPL 2439
+ S L G+ + TS+ N + + + +D+ SKKGFK + + CS
Sbjct: 655 LTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS----K 709
Query: 2440 KNGGILNRTAGAVGSKVHYFCKPGYRMVGHSN 2471
NGG GS Y C+ V H N
Sbjct: 710 DNGGCQQDCVNTFGS---YECQCRSGFVLHDN 738
Score = 68.2 bits (165), Expect = 1e-10
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 4/112 (3%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----F 83
K C V +GTI SP +P YP+ CTW I + +R++L+F +E +
Sbjct: 743 KEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAY 802
Query: 84 DILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKA 135
D L V+DG+ + + R G + P +++TGS + L F +D +V +GF+A
Sbjct: 803 DHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA 854
Score = 66.6 bits (161), Expect = 4e-10
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
ACG L G SP YP Y C WR+ V P I L F S ++ S YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDAS-VGLSGFAI 1555
+ +G +PL G + GS+ PE I S+ + L++ FRS ++ VG FA+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 65.9 bits (159), Expect = 7e-10
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
ACG TL+ ++ + SSP +P+ Y + C W I PG+ I L FT L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
E+ +AP G LP P++S+ + L + F S SN KGF A ++
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 64.3 bits (155), Expect = 2e-09
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
Query: 1994 SYPNNLDCTWRISLPIGYGAHIQFLNFS----TEANHDFLEIQNGPYHTSPMIGQFSGTD 2049
+YP +DC W I GYG + F F T+ +D++E+ +G T+P +G++ G+
Sbjct: 883 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG 942
Query: 2050 LPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2087
P + S L+ F+SD + ++GF L Y + + Q+
Sbjct: 943 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD 980
Score = 63.5 bits (153), Expect = 3e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CG +Q G SP +P+GY + +C W I +I L+F + L +D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG ++ L+ R G +LP IVST S L + F + +GF A+YE + CG
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CG- 436
Query: 148 PGEILKGVLHGTRFNIGDKIRYS 170
G++ K H N D R S
Sbjct: 437 -GDVKKDYGHIQSPNYPDDYRPS 458
Score = 62.8 bits (151), Expect = 6e-09
Identities = 29/96 (30%), Positives = 55/96 (57%), Gaps = 4/96 (4%)
Query: 779 YKDSLHCEWIIEAKPGHSIKITFDRFQ----TEVNYDTLEVRDGPASSSPLIGEYHGTQA 834
Y + CEW+I A+ G+ +++ F F+ T+ YD +E+ DG S++P +G Y G+
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Query: 835 PQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
P+ + S G+ + + F +D++ + GF + Y S +
Sbjct: 944 PEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQ 979
Score = 62.0 bits (149), Expect = 1e-08
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G SP YP Y +++C+W+I VT G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
+ DG AP G F G+ +P + ST ++L++ F+S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 60.5 bits (145), Expect = 3e-08
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 9/119 (7%)
Query: 1277 ECGGQIHAATSGRILSPGYPAPYDNN----LHCTWIIEADPGKTISLHFIVFD----TEM 1328
ECGGQ+ A + L + DNN + C W+I A+ G + L F F+ T+
Sbjct: 859 ECGGQVRADVKTKDLY-SHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDC 917
Query: 1329 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTS 1387
+D ++++DG + L + GS PE+++S +S+ ++F SD I+K GF ++++++
Sbjct: 918 GYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTST 976
Score = 59.3 bits (142), Expect = 7e-08
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 16/169 (9%)
Query: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNT----LTCLSGDRRVWDKPLPSCIAEC 1278
I +Y G F DT+V P Y ++G T LS + L C A C
Sbjct: 269 IMHYARNTFSRGIFLDTIV-----PKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPA-C 322
Query: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
G + +T G SP YP Y ++HC W I PG+ I L+F D + +D ++
Sbjct: 323 GETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQF-DSDFFISKSGFSI 1382
V DG L + GS LPE I ST + L ++F S ++ K F++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 57.4 bits (137), Expect = 3e-07
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
+C A CG + G SP +P+ Y C+W I+V PG + +NFT L
Sbjct: 318 KCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCW 376
Query: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFFVL 2249
DY+ V DG + +P G F G+ E S+ +++ ++F S++ GFF +
Sbjct: 377 YDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 53.9 bits (128), Expect = 3e-06
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 12/118 (10%)
Query: 208 CGGTLRG---TSSSISSPHF-PSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
CGG +R T S F + Y DC W I+AE G + LVF F++EE GY
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 260 DFLEI---SGTEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
D++E+ + AP + G P V S+ + + + F SD +KGF+ ++ K
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK 977
Score = 53.1 bits (126), Expect = 5e-06
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 1085 TCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
T L G + L +C A CG +++ + G SP +P+ Y + C+++I G+ I
Sbjct: 303 TRLSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII 361
Query: 1145 LRTRSFQLFEG-----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNG 1199
L S L+ D ++V DG + G F ++L I+ ST + LW+EF ++
Sbjct: 362 LNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV-STDSRLWVEFRSSS 420
Query: 1200 SDTDQGFQLTY 1210
+ +GF Y
Sbjct: 421 NWVGKGFFAVY 431
Score = 51.2 bits (121), Expect = 2e-05
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Query: 26 AAKGQNCGGLVQGPNGTIESPGFP----HGYPNYANCTWIIITGERNRIQLSFHTFALEE 81
A+ CGG V+ T + + YP +C W+I+ E ++L F TF +EE
Sbjct: 854 ASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE 913
Query: 82 D----FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137
+ +D + ++DG R G P + S G + + F +D ++ +GF Y
Sbjct: 914 ETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
Score = 47.0 bits (110), Expect = 3e-04
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
CG S G SP YP+ Y+A C++ I+V P E ++ F +++ L D E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
+ DG +A L GS E + ++T +++ + F + S +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 45.8 bits (107), Expect = 8e-04
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 931 CGGYIQGKSGTVLSPGFPDF----YPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SH 982
CGG ++ T F YP ++C W I G GV+++F TF +E +
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGY 919
Query: 983 DYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
DY+ + + + P + R GS P + + + ++F SD +I+ +GF++ ++
Sbjct: 920 DYMELFDGYDSTAPRLGRYCGSGPPEEVYS---AGDSVLVKFHSDDTITKKGFHLRYT 974
Score = 42.7 bits (99), Expect = 0.006
Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 1104 ECGASVKGNEGTLLSPNFPSNYDNNH----ECIYKIETEAGKGIHLRTRSFQLFEG---- 1155
ECG V+ + T + DNN+ +C + I E G G+ L ++F++ E
Sbjct: 859 ECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCG 918
Query: 1156 -DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
D ++++DG DS++ LG + + + S + + ++F+++ + T +GF L YTS
Sbjct: 919 YDYMELFDGYDSTAPRLGRYCGSGPPEEVY-SAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 41.2 bits (95), Expect = 0.019
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
+CPA E S+G SP YP Y C W I V P I + +D ++S +
Sbjct: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
D +EV DG ++PL G+ + S ++L++ + + KGF Y A
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEP-IVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 [Homo
sapiens]
Length = 840
Score = 226 bits (575), Expect = 4e-58
Identities = 166/535 (31%), Positives = 247/535 (46%), Gaps = 25/535 (4%)
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNH---ECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
C ++ EG + SP+ S +C Y I G GI ++ ++ L + + L V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1162 DGKDSSSRPLGTFTKNELLG--LILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
G S + +LG +L S +N L L F + GF++ Y ++ L+ C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECG 1279
P P +G + H T + C+ GY + G TL CL+G R W+ PSC+A CG
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFH-CDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1280 GQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP 1339
G IH AT GRI+SP NL C W+IEA G+ + LHF + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1340 VDSDILLKEWSGSALPE-DIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMP 1398
++ + +PE + S SL ++ S+ + S++F C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1399 Q-NGTRYGDSREAGDTVTFQCDPGYQLQGQA---KITCVQLNNRFFWQPDPPTCIAACGG 1454
N T G TF C PGY L+ I CV W P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEP-HWNDTEPACKAMCGG 459
Query: 1455 NLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDS 1514
L+ PAGV+LSP++PQ Y PG++C W V V + I L + N+ D L +++G+
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1515 NSPLIGSYQGSQAPERIESSGNSLFLAFRS---DASVGL-SGFAIEFKEKPR-EACFDPG 1569
++ ++ +G Q R+ SSG L L F++ + GL GF + FKE PR + C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1570 NIMNGTRVGT--DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
G R + D G+ +TYQC+ GY++L +TC SW P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 629
Score = 211 bits (538), Expect = 8e-54
Identities = 199/733 (27%), Positives = 304/733 (41%), Gaps = 101/733 (13%)
Query: 1801 VPCSGNFTQRRGTILSPGYPEPYGNNL---NCIWKIIVTEGSGIQIQVISFATEQNWDSL 1857
V C+ N ++ G + SP P L +C + I V G GI+IQV + Q + L
Sbjct: 101 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 1858 EIHDGGDV-TAPRLGSFSGTTVPA-LLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAA 1915
+ GG APRL + S +L S +N+L LHFQS GF + Y+ L +
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLS 219
Query: 1916 CQEPALPSNS-IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1974
C P P++ + + D + +F C+ GY LQG + C+ GT WN +P C+A+
Sbjct: 220 CGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 278
Query: 1975 CGGTL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
CGGT+ +TLG ++ SP G+ NL C W I G H+ F S + ++D L ++
Sbjct: 279 CGGTIHNATLGRIV-SPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 2033 NGPYHTSPMIGQFSGTDLPA-ALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+G SP+I D+P L+S + S+ N L ++A+E C
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC-FA 396
Query: 2092 PPFQNGYMINSD--YSVGQSVSFECYPGYILI--GHP-VLTCQHGINRNWNYPFPRCDAP 2146
P +G + +D Y G +F C PGY L G P + C +WN P C A
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 456
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIA 2202
CG ++ G + SP +P Y +DC+W + V + LLQ E +N D +
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI-----LLQVEILNVREGDMLT 511
Query: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS-----DFSNGGFFVLNFHAFQLK 2257
++DG ++ L G SS + L+F + + G FVL+F ++
Sbjct: 512 LFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFK--EVP 569
Query: 2258 KCQPPPAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
+ P +P E D G + YQC PGY L+G+DILTC+ L + + P
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQW--DLSWSAAPP 627
Query: 2315 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFD 2374
C+ I++ PG N + S+ F
Sbjct: 628 ACQK--------------IMTCADPGEIANGHRTA-------------------SDAGFP 654
Query: 2375 ALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCS 2434
GS Q L ++ + +S D T K ++ P C+
Sbjct: 655 V-----GSHVQYRCL----------PGYSLEGAAMLTCYSRDTGTPKWSDRV----PKCA 695
Query: 2435 LTH-PLKNGGI-------LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 2486
L + P N G+ L + G + +FC G+ ++G TC P QW S
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTS 753
Query: 2487 LTPLCQAVSCGIP 2499
PLC+ P
Sbjct: 754 QPPLCKVTQTTDP 766
Score = 208 bits (529), Expect = 9e-53
Identities = 159/557 (28%), Positives = 248/557 (44%), Gaps = 38/557 (6%)
Query: 1288 GRILSPGYPAPYDNNL---HCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDG--PVDS 1342
G + SP +P L CT+ I PG I + + ++L + G P +
Sbjct: 112 GYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLA 171
Query: 1343 DILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGT 1402
LL S + + S N L L F S GF I + + + C P P +G
Sbjct: 172 PRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPAHGD 230
Query: 1403 RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL-TGPAG 1461
G T TF CD GYQLQG+ + C+ R W + P+C+A+CGG + G
Sbjct: 231 VSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNATLG 289
Query: 1462 VILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGS 1521
I+SP P C W ++ + L F+ +++ D L + G SP+I
Sbjct: 290 RIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYD 349
Query: 1522 YQGSQAPER-IESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP----GNIMNGTR 1576
PER + S SL++ S+ ++ F+ + CF P GN+ T
Sbjct: 350 SDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV---TT 406
Query: 1577 VGTDFKLGSTITYQCDSGYKILDP---SSITCVIGADGKPSWDQVLPSCNAPCGGQYTGS 1633
+++ G+ T+ C GY + P ++I CV + P W+ P+C A CGG+ +
Sbjct: 407 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE--PHWNDTEPACKAMCGGELSEP 464
Query: 1634 EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS 1693
GVVLSP++P +Y+ GQ C++ + V +E + Q D+ LFDG AR+L+
Sbjct: 465 AGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLA 524
Query: 1694 SLSGSHSGETLPLATSNQILLRFSAKSG----ASARGFHFVYQAVPRTSDTQCSSVPEPR 1749
L G L L++ + L+F A G +GF ++ VPR +DT C +P P
Sbjct: 525 QLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPR-NDT-CPELPPPE 581
Query: 1750 YGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC--VVPCS- 1804
+G R S + G+++ ++C PGY L GS L CQ W+ P+C ++ C+
Sbjct: 582 WGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQKIMTCAD 637
Query: 1805 -GNFTQRRGTILSPGYP 1820
G T G+P
Sbjct: 638 PGEIANGHRTASDAGFP 654
Score = 187 bits (474), Expect = 2e-46
Identities = 187/740 (25%), Positives = 291/740 (39%), Gaps = 89/740 (12%)
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSL---HCEWIIEA 791
E+ T I+ V + T P C +++ G + P +L C + I
Sbjct: 82 ETTTTIITTTTVTTTVTSP---VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHV 138
Query: 792 KPGHSIKITFDRFQTEVNYDTLEVRDG--PASSSPLIGEYHGTQAPQFLISTGNFMYLLF 849
PG+ I+I + L + G P + L+ Q L S N + L F
Sbjct: 139 YPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHF 198
Query: 850 TTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDD 909
+ GF IHY++ L SC P P +G D T TF CD GY L +
Sbjct: 199 QSPRVPRGGGFRIHYQAYLL---SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGE 255
Query: 910 EPLVCERNHQ--WNHALPSCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHG 966
E L+C + WN PSC A CGG I + G ++SP +L C W IE + G
Sbjct: 256 ETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEG 315
Query: 967 KGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFIS 1025
+ + + F L+ +D L++ GS PV + S + + GL + + + +S
Sbjct: 316 RRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLS 373
Query: 1026 DFSISYEGFNITFSEYDLEPCDDPGVPAFS-RRIGFHFGVGDSLTFSCFLGYRLEGA--- 1081
+ + ++ F ++ + C P + + + G TFSC GY LE
Sbjct: 374 ETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 433
Query: 1082 TKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGK 1141
+ C+ W+ P C A CG + G +LSP++P +Y +C++ + + K
Sbjct: 434 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 1142 GIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD 1201
I L+ + EGD L ++DG S+R L + +L+S + L L+F
Sbjct: 494 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPD-LTLQFQAPPGP 552
Query: 1202 TD----QGFQLTYTSFDL-VKCEDPGIPNYGYRIRDEGH-FTDTVVLYSCNPGYAMHGSN 1255
+ QGF L + C + P +G+R G TV+ Y C PGY + GS+
Sbjct: 553 PNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 612
Query: 1256 TLTC---LSGDRRVWDKPLPSC--IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIE 1310
LTC LS W P+C I C
Sbjct: 613 ILTCQWDLS-----WSAAPPACQKIMTC-------------------------------- 635
Query: 1311 ADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFD 1370
ADPG+ + H D PV S + + G +L ++ +
Sbjct: 636 ADPGEIANGHRTASDAGF----------PVGSHVQYRCLPGYSLEG------AAMLTCYS 679
Query: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQA 1428
D K + C +PG+P+NG T Y +AG+++ F C G++L G+
Sbjct: 680 RDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEV 739
Query: 1429 KITCVQLNNRFFWQPDPPTC 1448
ITCV + W PP C
Sbjct: 740 TITCVP-GHPSQWTSQPPLC 758
Score = 178 bits (452), Expect = 7e-44
Identities = 154/585 (26%), Positives = 250/585 (42%), Gaps = 29/585 (4%)
Query: 384 GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY--PVQYEDNA-HCVW 440
G + T +T T + P+ C +N+ G + SP+ PV C +
Sbjct: 79 GEEETTTTIITTTTVTTTVTSPVL----CNNNISEGEGYVESPDLGSPVSRTLGLLDCTY 134
Query: 441 VITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQ 500
I P I++ + L + + L + G G +L + ++ S +N+
Sbjct: 135 SIHVY-PGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNR 193
Query: 501 MWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFEL 560
+ LH QS GF+ YQ CG P PA+G + + G T TF C + ++L
Sbjct: 194 LLLHFQSPRVPRGGGFRIHYQAYLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQL 252
Query: 561 VGERVITCQQNNQ--WSGNKPSCVFSCFFNF-TASSGIILSPNYPEEYGNNMNCVWLIIS 617
GE + C + W+G PSC+ SC A+ G I+SP G N+ C W+I +
Sbjct: 253 QGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEA 312
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQ 676
G R+HL F ++ D L V+ G V+ ++VP + L S + +E
Sbjct: 313 AEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELL 372
Query: 677 SDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGD-RFLLGSSVSFHCDDGF-VKTQGS 734
S+ ++ + F ++ C P + D + G+ +F C G+ ++ G
Sbjct: 373 SETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGP 432
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
+ + W+ T P C+A CGG L+ +GV+L P WP Y C W + +
Sbjct: 433 PNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEE 492
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTT--- 851
I + + D L + DG S+ ++ + G Q + L+S+G + L F
Sbjct: 493 KRILLQVEILNVREG-DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 551
Query: 852 -DNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHG--GDFGIRSTV-TFSCDPGYTLS 907
N GF++H++ V +D+C + P G R GD IR TV T+ C+PGY L
Sbjct: 552 PPNPGLGQGFVLHFKEVP-RNDTCPELPPPEWGWRTASHGDL-IRGTVLTYQCEPGYELL 609
Query: 908 DDEPLVCERNHQWNHALPSCDAL--CG--GYIQGKSGTVLSPGFP 948
+ L C+ + W+ A P+C + C G I T GFP
Sbjct: 610 GSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Score = 178 bits (452), Expect = 7e-44
Identities = 177/722 (24%), Positives = 274/722 (37%), Gaps = 95/722 (13%)
Query: 1626 CGGQYTGSEGVVLSPNY--PHNYTAGQI-CLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
C + EG V SP+ P + T G + C YSI V + + Q + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1683 DGTHAQA---RLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
G + RLL++ S G+ L T N++LL F + GF YQA +
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAYLLS-- 219
Query: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
C P P +G ++ G F C+ GY LQG L C + WN PSC
Sbjct: 220 --CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 275
Query: 1800 VVPCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLE 1858
+ C G G I+SP G NL C W I EG + + + +++ D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 1859 IHDGGDVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1917
+ GG +P + VP L S + LY+ S+ L ++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 1918 EPALPSNSIKIGD-RYMVNDVLSFQCEPGYTLQGR---SHISCMPGTVRRWNYPSPLCIA 1973
P L ++ D Y + +F C PGY L+ + I C+ T WN P C A
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 455
Query: 1974 TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQ-------FLNFSTEANH 2026
CGG LS GV+LSP +P SY DC W G H+Q +
Sbjct: 456 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 507
Query: 2027 DFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNR----QGFKLAYQA 2082
D L + +G ++ ++ Q G LLS+ + + F + QGF L ++
Sbjct: 508 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 567
Query: 2083 YELQN-CPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYP 2139
+ CP+ PP + G+ S D G ++++C PGY L+G +LTCQ + +W+
Sbjct: 568 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL--SWSAA 625
Query: 2140 FPRCD--APCGYNVTSQNG--TIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE 2195
P C C NG T GFP + C+ PG+ +
Sbjct: 626 PPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCL------PGYSL---------- 669
Query: 2196 AVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQ 2255
+ + L +S +T + LK+
Sbjct: 670 -------------EGAAMLTCYSRDTGTPKWSDRVPKCALKY------------------ 698
Query: 2256 LKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
+ C P ++ G+ +++ C+ G+ L+G +TC Q+ P
Sbjct: 699 -EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2316 CE 2317
C+
Sbjct: 758 CK 759
Score = 172 bits (437), Expect = 4e-42
Identities = 175/716 (24%), Positives = 269/716 (37%), Gaps = 86/716 (12%)
Query: 585 CFFNFTASSGIILSPNYPEEYGNNM---NCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
C N + G + SP+ + +C + I PG I + ++ + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 642 KDDGISDIT--VLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECH 699
G + +L S L S + + L FQS G GF I Y + C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 700 DPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPC 759
P P +G G + +FHCD G+ + QG E++ C L W+ P C A C
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGY-QLQGEETLIC-LNGTRPSWNGETPSCMASC 279
Query: 760 GGHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
GG + A+ G I+ P G +L C W+IEA G + + F+R + + D L VR G
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 819 PASSSPLIGEYHGTQAPQ-FLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
+ SP+I + P+ LIS +Y+ ++ + + + +E+ E D C P
Sbjct: 340 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEA--FEEDRCFAP 397
Query: 878 GIPVNGHRHGG------DFGIRSTVTFSCDPGYTLSDDEP-----LVCERNHQWNHALPS 926
+ HG ++ + TFSC PGY L P V WN P+
Sbjct: 398 FL-----AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 452
Query: 927 CDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLL 986
C A+CGG + +G VLSP +P Y +C W + V K + + ++ L
Sbjct: 453 CKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 512
Query: 987 ITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISY----EGFNITFSEYD 1042
DG + +A+L G P + L L+F + +GF + F E
Sbjct: 513 FDGDGPSARVLAQLRG---PQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 569
Query: 1043 L-EPCDDPGVPAFSRRIGFHFGV--GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
+ C + P + R H + G LT+ C GY L G+ LTC WSA P
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPP 627
Query: 1100 RCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK 1159
C +++ P N H G + R EG +
Sbjct: 628 AC------------QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAML 675
Query: 1160 VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
+D T W SD L Y C
Sbjct: 676 TCYSRD---------------------TGTPKW-------SDRVPKCALKYE-----PCL 702
Query: 1220 DPGIPNYGYRIRDEGHF-TDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
+PG+P GY+ + H+ + + C G+ + G T+TC+ G W P C
Sbjct: 703 NPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 160 bits (405), Expect = 2e-38
Identities = 196/791 (24%), Positives = 294/791 (37%), Gaps = 133/791 (16%)
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGK---ECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
C N++ G + SP+ P +C + + V P + I + ++ N+ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1509 YEGED--------SNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
G +NS ++G Q ++P N L L F+S GF I ++
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT------NRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
F P V TD G T T+ CDSGY++ ++ C+ G +PSW+ P
Sbjct: 217 LLSCGFPPRPAHGDVSV-TDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1621 SCNAPCGGQ-YTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ------- 1672
SC A CGG + + G ++SP C + I + + F
Sbjct: 274 SCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 333
Query: 1673 -------TALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASAR 1725
+ L+ + D R L S + S E L +N +LL ++ R
Sbjct: 334 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 393
Query: 1726 GFH-FVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGS---TALH 1781
F F+ T+D E+ G++ F C PGY L+ A+
Sbjct: 394 CFAPFLAHGNVTTTDP----------------EYRPGALATFSCLPGYALEPPGPPNAIE 437
Query: 1782 CQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGI 1841
C V WNDT P+C C G ++ G +LSP +P+ Y +C+W + V E I
Sbjct: 438 C--VDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI 495
Query: 1842 QIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVA- 1900
+QV + D L + DG +A L G L S+ L L FQ+
Sbjct: 496 LLQV-EILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPN 554
Query: 1901 ---AAGFHLEYKTVGLA-ACQEPALPS---NSIKIGDRYMVNDVLSFQCEPGYTLQGRSH 1953
GF L +K V C E P + GD + VL++QCEPGY L G
Sbjct: 555 PGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTVLTYQCEPGYELLGSDI 613
Query: 1954 ISCMPGTVRRWNYPSPLC--IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 2011
++C W+ P C I TC PG N P+G
Sbjct: 614 LTCQWDL--SWSAAPPACQKIMTCAD--------------PGEIANGHRTASDAGFPVG- 656
Query: 2012 GAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQ 2071
+H+Q Y P G L A + T + D
Sbjct: 657 -SHVQ-------------------YRCLP------GYSLEGAAMLTCYSR------DTGT 684
Query: 2072 NRQGFKLAYQAYELQNCPDPPPFQNGY--MINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2129
+ ++ A + + C +P +NGY + Y G+S+ F CY G+ LIG +TC
Sbjct: 685 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Query: 2130 HGINRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWL---ITVPPGHGVY 2186
G W P C VT P E L I L + + G GVY
Sbjct: 745 PGHPSQWTSQPPLC------KVTQTT----DPSRQLEGGNLALAILLPLGLVIVLGSGVY 794
Query: 2187 INFTLLQTEAV 2197
I +T LQ +++
Sbjct: 795 IYYTKLQGKSL 805
Score = 139 bits (350), Expect = 5e-32
Identities = 155/573 (27%), Positives = 226/573 (39%), Gaps = 69/573 (12%)
Query: 32 CGGLVQGPNGTIESPGFPHGYP-----NYANCTWIIITGERNRIQLSFHTFALEEDFDIL 86
C + G +ESP G P +CT+ I I++ T L ++ ++L
Sbjct: 103 CNNNISEGEGYVESPDL--GSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 87 SVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILT-------LWFTTDFAVSAQGFKALYEV 139
+ G L RL SS++ G +L L F + GF+ Y+
Sbjct: 161 VLAGGGSP--GLAPRLLA---NSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 140 LPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
+CG P G + T + G + C GY L+G L C+ G SW+
Sbjct: 216 YLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL--NGTRPSWNGET 272
Query: 200 PFCRAEGACGGTL-RGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG 258
P C A +CGGT+ T I SP N C W I A G + L F L+E
Sbjct: 273 PSCMA--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED 330
Query: 259 YDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELK 318
D L + +P SPVI + D R +AQ
Sbjct: 331 NDRLMVRSGGSPL---------SPVIYDSD------MDDVPERGLISDAQ---------- 365
Query: 319 SRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCED 378
S V++L + +LS A D C P + R GA FSC
Sbjct: 366 SLYVELLSETPAN--PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLP 423
Query: 379 NYVLQ---GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
Y L+ +I C V T W+D P C+A CG L P+GV+ SP++P Y
Sbjct: 424 GYALEPPGPPNAIEC--VDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPG 480
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
CVW + + +K I L E + G D LT+ D G + VL L G ++
Sbjct: 481 QDCVWGVHVQE-EKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLL 536
Query: 496 SMSNQMWLHLQSDDSIGSP----GFKAVYQEIEKGG-CGDPGIPAYGKRTGS--SFLHGD 548
S + L Q+ +P GF ++E+ + C + P +G RT S + G
Sbjct: 537 SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGT 596
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
LT++C +EL+G ++TCQ + WS P+C
Sbjct: 597 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 136 bits (343), Expect = 3e-31
Identities = 164/689 (23%), Positives = 261/689 (37%), Gaps = 60/689 (8%)
Query: 2147 CGYNVTSQNGTIYSP--GFPDEYPI-LKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
C N++ G + SP G P + L DC + I V PG+G+ I L + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2204 WDGPDQNSPQLG--VFSGNTAL---ETAYSSTNQVLLKFHSD-FSNGGFFVLNFHAFQLK 2257
G SP L + + ++ L + S TN++LL F S GG F +++ A+ L
Sbjct: 163 AGG---GSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS 219
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
C PP ++ D G + C GY L G + L C ++ + G P+C
Sbjct: 220 -CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2318 AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALE 2377
A C + + G I+SP G + TC W I+ + + + ++ D L
Sbjct: 277 ASC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCS 2434
V G S SP++ + + S + LY+ ++ + +R+ A C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2435 LTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMV--GHSNATCRRNPLGMYQWDSLTPLCQ 2492
G+ + C PGY + G NA +P + W+ P C+
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACK 454
Query: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATA------VCQEDGLWSN 2546
A+ CG S G ++ +C G ++ ++ V + D L
Sbjct: 455 AM-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLF 513
Query: 2547 KGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQAN 2606
G P+ + + AQL R + S + Q PG G
Sbjct: 514 DGDGPSAR------VLAQLRGPQPRRRLLSSGPDLTLQ--FQAPPGPPNPGL-------- 557
Query: 2607 GTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRECL 2664
G + + R +C L P G + + + G + C GY L+GS + C
Sbjct: 558 GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQ 617
Query: 2665 ANGLWSGSETRCLA-GHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC 2721
+ WS + C C P I NGH S GF V Y+C PG+ L G ++ C
Sbjct: 618 WDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTC 677
Query: 2722 LQDH----KWSGQTPVCVPI--TCGHPGNPAHGFTN--GSEFNLNDVVNFTCNTGYLLQG 2773
KWS + P C C +PG P +G+ + + + F C G+ L G
Sbjct: 678 YSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIG 737
Query: 2774 VSRAQCRSN--GQWSSPLPTCRVVNCSDP 2800
C QW+S P C+V +DP
Sbjct: 738 EVTITCVPGHPSQWTSQPPLCKVTQTTDP 766
Score = 127 bits (318), Expect = 3e-28
Identities = 164/674 (24%), Positives = 259/674 (38%), Gaps = 103/674 (15%)
Query: 138 EVLPSHTCGNP---GEILKGVLHGTRFNIGDKIRYSCLPGYILE---GHAILTCIVSPGN 191
E+LP P E L +LHG G ++ Y LPG L G T +
Sbjct: 34 EILPEPGSETPTVASEALAELLHGALLRRGPEMGY--LPGPPLGPEGGEEETTTTIITTT 91
Query: 192 GASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNA---DCTWTILAEPGDTIAL 248
+ +P C + + SP S DCT++I PG I +
Sbjct: 92 TVTTTVTSPVL-----CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEI 146
Query: 249 VFTDFQLEEGYDFLEISGTEAP----------SIWLTGMNLPSPVISSKNWLRLHFTSDS 298
L + + L ++G +P S+ G L SP N L LHF S
Sbjct: 147 QVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPR 202
Query: 299 NHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENG 358
R GF +Q L S G P+ G V+D+ P
Sbjct: 203 VPRGGGFRIHYQAY----LLSCGFPPRPAH------------GDVSVTDLHP-------- 238
Query: 359 RRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRG 418
G F C+ Y LQG +++ C + T +W+ P C A +CG +
Sbjct: 239 ----------GGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSCMA-SCGGTIHN 285
Query: 419 PS-GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGD 477
+ G I SP N C WVI + + + L FE L+ D L V G
Sbjct: 286 ATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGS--P 342
Query: 478 TRSVLYVLTGSSVPDL-IVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAY 536
V+Y VP+ ++S + +++ L S+ ++ E+ C P + A+
Sbjct: 343 LSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AH 401
Query: 537 GK--RTGSSFLHGDTLTFECPAAFELVGE---RVITCQQNNQ--WSGNKPSCVFSCFFNF 589
G T + G TF C + L I C + W+ +P+C C
Sbjct: 402 GNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGEL 461
Query: 590 TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDI 649
+ +G++LSP++P+ Y +CVW + + RI L +V + D L + D
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSA 520
Query: 650 TVLGTFSGNEVPSQLASSGHIVRLEFQS----DHSTTGRGFNITYTTFGQNE-CHDPGIP 704
VL G + +L SSG + L+FQ+ + G+GF + + +N+ C + P
Sbjct: 521 RVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPP 580
Query: 705 INGRR---FGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE----- 756
G R GD + G+ +++ C+ G+ + GS+ +TC ++ WS+ P C+
Sbjct: 581 EWGWRTASHGD-LIRGTVLTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPACQKIMTC 635
Query: 757 ----APCGGHLTAS 766
GH TAS
Sbjct: 636 ADPGEIANGHRTAS 649
Score = 97.4 bits (241), Expect = 2e-19
Identities = 137/572 (23%), Positives = 201/572 (35%), Gaps = 112/572 (19%)
Query: 31 NCGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVY 89
+CGG + G I SP C W+I E R+ L F +L+ED D L V
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 90 DGQPQQGNLKVRLSGFQLPS-SIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
G + +P ++S L + ++ + +E C P
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 149 GEILKGVLHGT------RFNIGDKIRYSCLPGYILEGHAILTCI--VSPGNGASWDFPAP 200
+ HG + G +SCLPGY LE I V P W+ P
Sbjct: 398 F-----LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE-PHWNDTEP 451
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYD 260
C+A CGG L + + SP +P Y DC W + + I L + EG D
Sbjct: 452 ACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-D 508
Query: 261 FLEISGTEAPSIW-LTGMNLPSP---VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
L + + PS L + P P ++SS L L F + G F +
Sbjct: 509 MLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH---- 564
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-GANVQFS 375
K +P +D CP+ PE G R S + G + +
Sbjct: 565 -----FKEVPR------------------NDTCPELPPPEWGWRTASHGDLIRGTVLTYQ 601
Query: 376 CEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
CE Y L GS +TCQ +WS P C+
Sbjct: 602 CEPGYELLGSDILTCQWDL----SWSAAPPACQK-------------------------- 631
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
++T DP E+ G+ T + DAG + L G
Sbjct: 632 -----IMTCADPG----------EIANGHRTAS--DAGFPVGSHVQYRCLPG-------Y 667
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQE--IEKGGCGDPGIPAYGKRT--GSSFLHGDTLT 551
S+ L S D+ G+P + + ++ C +PG+P G +T + G++L
Sbjct: 668 SLEGAAMLTCYSRDT-GTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 726
Query: 552 FECPAAFELVGERVITCQQN--NQWSGNKPSC 581
F C FEL+GE ITC +QW+ P C
Sbjct: 727 FFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 92.0 bits (227), Expect = 9e-18
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 15/184 (8%)
Query: 2684 PDPIVNGHISGDGFSYRDTVV-YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI-TCGH 2741
P P + G R TV+ YQC PG+ L+G+ + C D WS P C I TC
Sbjct: 578 PPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCAD 637
Query: 2742 PGNPAHGFTNGSE--FNLNDVVNFTCNTGYLLQGVSRAQCRSNG----QWSSPLPTC--R 2793
PG A+G S+ F + V + C GY L+G + C S +WS +P C +
Sbjct: 638 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 697
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRS 2851
C +PG EN Q + ++ G S+ + C +GF L+G +TC+ W
Sbjct: 698 YEPCLNPGVPENGY---QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 754
Query: 2852 LPKC 2855
P C
Sbjct: 755 PPLC 758
Score = 87.8 bits (216), Expect = 2e-16
Identities = 90/359 (25%), Positives = 143/359 (39%), Gaps = 41/359 (11%)
Query: 2928 AHGSRLGDD--FKTKSLLRFSCEMGHQLR--GSPERTCLLNGS---WSGLQPVCEAVSCG 2980
AHG+ D ++ +L FSC G+ L G P ++ + W+ +P C+A+ CG
Sbjct: 400 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM-CG 458
Query: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGY---------KTSGLMTRHCTANGTWTGTAP 3031
+ G+++S D S W + + L R + G P
Sbjct: 459 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGP 518
Query: 3032 DCTIIS-CGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 3090
+++ P + G D T + +Q PG + + K+ N +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLT----LQFQAPPGPPNPGLGQGFVLHFKEVPRNDT- 573
Query: 3091 PVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEI 3148
CP+ PP + G T D G+ ++Y C GY+L S IL+C+ W
Sbjct: 574 -------CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP 626
Query: 3149 PQCLPVF-CGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT---- 3201
P C + C DPG A G S F S V ++C + L G++ C + T
Sbjct: 627 PACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPK 686
Query: 3202 WSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
WS P C + C +PG P G Q Y+ G ++ F C +G+ + G T TC+
Sbjct: 687 WSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Score = 82.8 bits (203), Expect = 6e-15
Identities = 56/180 (31%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
Query: 2879 GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-- 2936
G V+ Y C L+G+D CQ D WS A P C C DPG A+G R D
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAG 652
Query: 2937 FKTKSLLRFSCEMGHQLRGSPERTCLLNGS----WSGLQPVC--EAVSCGNPGTPTNG-M 2989
F S +++ C G+ L G+ TC + WS P C + C NPG P NG
Sbjct: 653 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 712
Query: 2990 IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN--GTWTGTAPDCTIISCGDPGTLANG 3047
+ S+ + C+EG++ G +T C WT P C + DP G
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEG 772
Score = 82.4 bits (202), Expect = 7e-15
Identities = 132/589 (22%), Positives = 202/589 (34%), Gaps = 135/589 (22%)
Query: 2858 ISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSH--WSGALPHCTG 2915
+SCG P PA+ ++ G + C L G +T +C + W+G P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 277
Query: 2916 NNPGFC-----GDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL-------- 2962
+ G G +P G +G + + ++ + G +L ER L
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAA--EGRRLHLHFERVSLDEDNDRLM 335
Query: 2963 LNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGI---LFSSSVIYACWEGYKTSGLMTRH 3019
+ S L PV + P G+I + + L S + +
Sbjct: 336 VRSGGSPLSPVIYDSDMDD--VPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 393
Query: 3020 C----TANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTS 3075
C A+G T T P+ PG LA ++ C PGY +E
Sbjct: 394 CFAPFLAHGNVTTTDPEYR------PGALA---------------TFSCLPGYALEPPGP 432
Query: 3076 AT-IRCTK--DGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSH 3132
I C + WN ++P CKA +C G V D+ S C+ G +
Sbjct: 433 PNAIECVDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQE 491
Query: 3133 SA--ILSCEGRGVWKGEI------------------------------PQCLPVFCGDPG 3160
+L E V +G++ P F PG
Sbjct: 492 EKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 551
Query: 3161 IPAEGRLSGKSFTYK-----------------------------SEVFFQCKSPFILVGS 3191
P G G +K + + +QC+ + L+GS
Sbjct: 552 PPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGS 611
Query: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS-RGYEVGSTVFFRCRKGYHI 3250
CQ D +WS P C TC DPG G + +S G+ VGS V +RC GY +
Sbjct: 612 DILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSL 669
Query: 3251 QGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF-------GYTLVYTC 3303
+G+ TC + T + ++ +P + E + V T G +L + C
Sbjct: 670 EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFC 729
Query: 3304 HPGFFLAGGSEHRTCKA--DMKWTGKSPVCKSKGVREVNETVTKTPVPS 3350
+ GF L G TC +WT + P+CK VT+T PS
Sbjct: 730 YEGFELI-GEVTITCVPGHPSQWTSQPPLCK----------VTQTTDPS 767
Score = 79.3 bits (194), Expect = 6e-14
Identities = 58/200 (29%), Positives = 87/200 (43%), Gaps = 12/200 (6%)
Query: 2978 SCGNPGTPTNGMIVSSDGILFSSSVI-YACWEGYKTSGLMTRHCTANGTWTGTAPDCT-I 3035
+C P G +S G L +V+ Y C GY+ G C + +W+ P C I
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 3036 ISCGDPGTLANGIQFGTD--FTFNKTVSYQCNPGYVMEAVTSATI--RCTKDGRWNPSKP 3091
++C DPG +ANG + +D F V Y+C PGY +E T R T +W+ P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 3092 VC--KAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSC--EGRGVWK 3145
C K C P +NG T+ ++ G S+ + C +G++L ++C W
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 3146 GEIPQCLPVFCGDPGIPAEG 3165
+ P C DP EG
Sbjct: 753 SQPPLCKVTQTTDPSRQLEG 772
Score = 70.9 bits (172), Expect = 2e-11
Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 12/179 (6%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI-SCGHPGVPANAVLTGE--LFT 2877
G + Y C+ G+ LLGS LTC + W + P C I +C PG AN T F
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Query: 2878 YGAVVHYSCRGSESLIGNDTRVCQE----DSHWSGALPHCTGNNPGFCGDPGTPAHG--S 2931
G+ V Y C SL G C WS +P C C +PG P +G +
Sbjct: 655 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEP-CLNPGVPENGYQT 713
Query: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN--GSWSGLQPVCEAVSCGNPGTPTNG 2988
++ LRF C G +L G TC+ W+ P+C+ +P G
Sbjct: 714 LYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEG 772
Score = 61.2 bits (147), Expect = 2e-08
Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 15/191 (7%)
Query: 2571 WRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC-RVISCGSLSFP 2629
WR S G + C PGY L G +L CQ + +W+ P+C ++++C
Sbjct: 584 WRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP--PACQKIMTCADPGEI 641
Query: 2630 PNGNKIGTLTVY--GATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCLAGH--C 2681
NG++ + + G+ + C GY+L G+ + C + WS +C + C
Sbjct: 642 ANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPC 701
Query: 2682 GSPDPIVNGHISGDGFSYR--DTVVYQCNPGFRLVGTSVRICLQDH--KWSGQTPVCVPI 2737
+P NG+ + Y+ +++ + C GF L+G C+ H +W+ Q P+C
Sbjct: 702 LNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVT 761
Query: 2738 TCGHPGNPAHG 2748
P G
Sbjct: 762 QTTDPSRQLEG 772
Score = 43.1 bits (100), Expect = 0.005
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ--WSSPLPTCRV 2794
++CG P PAHG + ++ + F C++GY LQG C + + W+ P+C +
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-M 276
Query: 2795 VNCSDPGFVENA 2806
+C G + NA
Sbjct: 277 ASCG--GTIHNA 286
Score = 33.9 bits (76), Expect = 3.0
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Query: 3035 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR--WNPSKPV 3092
++SCG P A+G TD T ++ C+ GY ++ T+ C R WN P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQG--EETLICLNGTRPSWNGETPS 274
Query: 3093 CKA 3095
C A
Sbjct: 275 CMA 277
Score = 33.9 bits (76), Expect = 3.0
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGL---WDRSLPKCLAISCGHPGVPANAVL 2871
G + +HC G+ L G L C+ NG W+ P C+A SCG G NA L
Sbjct: 239 GGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA-SCG--GTIHNATL 288
Score = 33.1 bits (74), Expect = 5.1
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 3157 GDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT 3216
G PG+ A L+ S + +V + +L S RV + G Q + +
Sbjct: 166 GSPGL-APRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 3217 CPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL--ANLTWSGIQTECI 3272
C P P G S G T F C GY +QG T CL +W+G C+
Sbjct: 220 CGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 33.1 bits (74), Expect = 5.1
Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 3468 QDPLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHE 3527
Q PL ++ G++A AIL+P +I+ G Y+Y + + K + H
Sbjct: 754 QPPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHS 813
Query: 3528 NS--NGQASFENPMYD 3541
S ++ F NP+Y+
Sbjct: 814 YSPITVESDFSNPLYE 829
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo
sapiens]
Length = 910
Score = 226 bits (575), Expect = 4e-58
Identities = 166/535 (31%), Positives = 247/535 (46%), Gaps = 25/535 (4%)
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNH---ECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
C ++ EG + SP+ S +C Y I G GI ++ ++ L + + L V
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1162 DGKDSSSRPLGTFTKNELLG--LILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
G S + +LG +L S +N L L F + GF++ Y ++ L+ C
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 291
Query: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECG 1279
P P +G + H T + C+ GY + G TL CL+G R W+ PSC+A CG
Sbjct: 292 FPPRPAHGDVSVTDLHPGGTATFH-CDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 350
Query: 1280 GQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP 1339
G IH AT GRI+SP NL C W+IEA G+ + LHF + +D L V G
Sbjct: 351 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 410
Query: 1340 VDSDILLKEWSGSALPE-DIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMP 1398
++ + +PE + S SL ++ S+ + S++F C P +
Sbjct: 411 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 470
Query: 1399 Q-NGTRYGDSREAGDTVTFQCDPGYQLQGQA---KITCVQLNNRFFWQPDPPTCIAACGG 1454
N T G TF C PGY L+ I CV W P C A CGG
Sbjct: 471 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEP-HWNDTEPACKAMCGG 529
Query: 1455 NLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDS 1514
L+ PAGV+LSP++PQ Y PG++C W V V + I L + N+ D L +++G+
Sbjct: 530 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 588
Query: 1515 NSPLIGSYQGSQAPERIESSGNSLFLAFRS---DASVGL-SGFAIEFKEKPR-EACFDPG 1569
++ ++ +G Q R+ SSG L L F++ + GL GF + FKE PR + C +
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 648
Query: 1570 NIMNGTRVGT--DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
G R + D G+ +TYQC+ GY++L +TC SW P+C
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 699
Score = 211 bits (538), Expect = 8e-54
Identities = 199/733 (27%), Positives = 304/733 (41%), Gaps = 101/733 (13%)
Query: 1801 VPCSGNFTQRRGTILSPGYPEPYGNNL---NCIWKIIVTEGSGIQIQVISFATEQNWDSL 1857
V C+ N ++ G + SP P L +C + I V G GI+IQV + Q + L
Sbjct: 171 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 230
Query: 1858 EIHDGGDV-TAPRLGSFSGTTVPA-LLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAA 1915
+ GG APRL + S +L S +N+L LHFQS GF + Y+ L +
Sbjct: 231 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLS 289
Query: 1916 CQEPALPSNS-IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1974
C P P++ + + D + +F C+ GY LQG + C+ GT WN +P C+A+
Sbjct: 290 CGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 348
Query: 1975 CGGTL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
CGGT+ +TLG ++ SP G+ NL C W I G H+ F S + ++D L ++
Sbjct: 349 CGGTIHNATLGRIV-SPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 2033 NGPYHTSPMIGQFSGTDLPA-ALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+G SP+I D+P L+S + S+ N L ++A+E C
Sbjct: 408 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC-FA 466
Query: 2092 PPFQNGYMINSD--YSVGQSVSFECYPGYILI--GHP-VLTCQHGINRNWNYPFPRCDAP 2146
P +G + +D Y G +F C PGY L G P + C +WN P C A
Sbjct: 467 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 526
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIA 2202
CG ++ G + SP +P Y +DC+W + V + LLQ E +N D +
Sbjct: 527 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI-----LLQVEILNVREGDMLT 581
Query: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS-----DFSNGGFFVLNFHAFQLK 2257
++DG ++ L G SS + L+F + + G FVL+F ++
Sbjct: 582 LFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFK--EVP 639
Query: 2258 KCQPPPAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
+ P +P E D G + YQC PGY L+G+DILTC+ L + + P
Sbjct: 640 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQW--DLSWSAAPP 697
Query: 2315 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFD 2374
C+ I++ PG N + S+ F
Sbjct: 698 ACQK--------------IMTCADPGEIANGHRTA-------------------SDAGFP 724
Query: 2375 ALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCS 2434
GS Q L ++ + +S D T K ++ P C+
Sbjct: 725 V-----GSHVQYRCL----------PGYSLEGAAMLTCYSRDTGTPKWSDRV----PKCA 765
Query: 2435 LTH-PLKNGGI-------LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 2486
L + P N G+ L + G + +FC G+ ++G TC P QW S
Sbjct: 766 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTS 823
Query: 2487 LTPLCQAVSCGIP 2499
PLC+ P
Sbjct: 824 QPPLCKVTQTTDP 836
Score = 208 bits (529), Expect = 9e-53
Identities = 159/557 (28%), Positives = 248/557 (44%), Gaps = 38/557 (6%)
Query: 1288 GRILSPGYPAPYDNNL---HCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDG--PVDS 1342
G + SP +P L CT+ I PG I + + ++L + G P +
Sbjct: 182 GYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLA 241
Query: 1343 DILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGT 1402
LL S + + S N L L F S GF I + + + C P P +G
Sbjct: 242 PRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPAHGD 300
Query: 1403 RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL-TGPAG 1461
G T TF CD GYQLQG+ + C+ R W + P+C+A+CGG + G
Sbjct: 301 VSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNATLG 359
Query: 1462 VILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGS 1521
I+SP P C W ++ + L F+ +++ D L + G SP+I
Sbjct: 360 RIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYD 419
Query: 1522 YQGSQAPER-IESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP----GNIMNGTR 1576
PER + S SL++ S+ ++ F+ + CF P GN+ T
Sbjct: 420 SDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV---TT 476
Query: 1577 VGTDFKLGSTITYQCDSGYKILDP---SSITCVIGADGKPSWDQVLPSCNAPCGGQYTGS 1633
+++ G+ T+ C GY + P ++I CV + P W+ P+C A CGG+ +
Sbjct: 477 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE--PHWNDTEPACKAMCGGELSEP 534
Query: 1634 EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS 1693
GVVLSP++P +Y+ GQ C++ + V +E + Q D+ LFDG AR+L+
Sbjct: 535 AGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLA 594
Query: 1694 SLSGSHSGETLPLATSNQILLRFSAKSG----ASARGFHFVYQAVPRTSDTQCSSVPEPR 1749
L G L L++ + L+F A G +GF ++ VPR +DT C +P P
Sbjct: 595 QLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPR-NDT-CPELPPPE 651
Query: 1750 YGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC--VVPCS- 1804
+G R S + G+++ ++C PGY L GS L CQ W+ P+C ++ C+
Sbjct: 652 WGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQKIMTCAD 707
Query: 1805 -GNFTQRRGTILSPGYP 1820
G T G+P
Sbjct: 708 PGEIANGHRTASDAGFP 724
Score = 187 bits (474), Expect = 2e-46
Identities = 187/740 (25%), Positives = 291/740 (39%), Gaps = 89/740 (12%)
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSL---HCEWIIEA 791
E+ T I+ V + T P C +++ G + P +L C + I
Sbjct: 152 ETTTTIITTTTVTTTVTSP---VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHV 208
Query: 792 KPGHSIKITFDRFQTEVNYDTLEVRDG--PASSSPLIGEYHGTQAPQFLISTGNFMYLLF 849
PG+ I+I + L + G P + L+ Q L S N + L F
Sbjct: 209 YPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHF 268
Query: 850 TTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDD 909
+ GF IHY++ L SC P P +G D T TF CD GY L +
Sbjct: 269 QSPRVPRGGGFRIHYQAYLL---SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGE 325
Query: 910 EPLVCERNHQ--WNHALPSCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHG 966
E L+C + WN PSC A CGG I + G ++SP +L C W IE + G
Sbjct: 326 ETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEG 385
Query: 967 KGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFIS 1025
+ + + F L+ +D L++ GS PV + S + + GL + + + +S
Sbjct: 386 RRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLS 443
Query: 1026 DFSISYEGFNITFSEYDLEPCDDPGVPAFS-RRIGFHFGVGDSLTFSCFLGYRLEGA--- 1081
+ + ++ F ++ + C P + + + G TFSC GY LE
Sbjct: 444 ETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 503
Query: 1082 TKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGK 1141
+ C+ W+ P C A CG + G +LSP++P +Y +C++ + + K
Sbjct: 504 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 563
Query: 1142 GIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD 1201
I L+ + EGD L ++DG S+R L + +L+S + L L+F
Sbjct: 564 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPD-LTLQFQAPPGP 622
Query: 1202 TD----QGFQLTYTSFDL-VKCEDPGIPNYGYRIRDEGH-FTDTVVLYSCNPGYAMHGSN 1255
+ QGF L + C + P +G+R G TV+ Y C PGY + GS+
Sbjct: 623 PNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 682
Query: 1256 TLTC---LSGDRRVWDKPLPSC--IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIE 1310
LTC LS W P+C I C
Sbjct: 683 ILTCQWDLS-----WSAAPPACQKIMTC-------------------------------- 705
Query: 1311 ADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFD 1370
ADPG+ + H D PV S + + G +L ++ +
Sbjct: 706 ADPGEIANGHRTASDAGF----------PVGSHVQYRCLPGYSLEG------AAMLTCYS 749
Query: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQA 1428
D K + C +PG+P+NG T Y +AG+++ F C G++L G+
Sbjct: 750 RDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEV 809
Query: 1429 KITCVQLNNRFFWQPDPPTC 1448
ITCV + W PP C
Sbjct: 810 TITCVP-GHPSQWTSQPPLC 828
Score = 178 bits (452), Expect = 7e-44
Identities = 154/585 (26%), Positives = 250/585 (42%), Gaps = 29/585 (4%)
Query: 384 GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY--PVQYEDNA-HCVW 440
G + T +T T + P+ C +N+ G + SP+ PV C +
Sbjct: 149 GEEETTTTIITTTTVTTTVTSPVL----CNNNISEGEGYVESPDLGSPVSRTLGLLDCTY 204
Query: 441 VITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQ 500
I P I++ + L + + L + G G +L + ++ S +N+
Sbjct: 205 SIHVY-PGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNR 263
Query: 501 MWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFEL 560
+ LH QS GF+ YQ CG P PA+G + + G T TF C + ++L
Sbjct: 264 LLLHFQSPRVPRGGGFRIHYQAYLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQL 322
Query: 561 VGERVITCQQNNQ--WSGNKPSCVFSCFFNF-TASSGIILSPNYPEEYGNNMNCVWLIIS 617
GE + C + W+G PSC+ SC A+ G I+SP G N+ C W+I +
Sbjct: 323 QGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEA 382
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQ 676
G R+HL F ++ D L V+ G V+ ++VP + L S + +E
Sbjct: 383 AEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELL 442
Query: 677 SDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGD-RFLLGSSVSFHCDDGF-VKTQGS 734
S+ ++ + F ++ C P + D + G+ +F C G+ ++ G
Sbjct: 443 SETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGP 502
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
+ + W+ T P C+A CGG L+ +GV+L P WP Y C W + +
Sbjct: 503 PNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEE 562
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTT--- 851
I + + D L + DG S+ ++ + G Q + L+S+G + L F
Sbjct: 563 KRILLQVEILNVREG-DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 621
Query: 852 -DNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHG--GDFGIRSTV-TFSCDPGYTLS 907
N GF++H++ V +D+C + P G R GD IR TV T+ C+PGY L
Sbjct: 622 PPNPGLGQGFVLHFKEVP-RNDTCPELPPPEWGWRTASHGDL-IRGTVLTYQCEPGYELL 679
Query: 908 DDEPLVCERNHQWNHALPSCDAL--CG--GYIQGKSGTVLSPGFP 948
+ L C+ + W+ A P+C + C G I T GFP
Sbjct: 680 GSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 724
Score = 178 bits (452), Expect = 7e-44
Identities = 177/722 (24%), Positives = 274/722 (37%), Gaps = 95/722 (13%)
Query: 1626 CGGQYTGSEGVVLSPNY--PHNYTAGQI-CLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
C + EG V SP+ P + T G + C YSI V + + Q + + +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1683 DGTHAQA---RLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
G + RLL++ S G+ L T N++LL F + GF YQA +
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAYLLS-- 289
Query: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
C P P +G ++ G F C+ GY LQG L C + WN PSC
Sbjct: 290 --CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 345
Query: 1800 VVPCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLE 1858
+ C G G I+SP G NL C W I EG + + + +++ D L
Sbjct: 346 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 405
Query: 1859 IHDGGDVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1917
+ GG +P + VP L S + LY+ S+ L ++ C
Sbjct: 406 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 465
Query: 1918 EPALPSNSIKIGD-RYMVNDVLSFQCEPGYTLQGR---SHISCMPGTVRRWNYPSPLCIA 1973
P L ++ D Y + +F C PGY L+ + I C+ T WN P C A
Sbjct: 466 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 525
Query: 1974 TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQ-------FLNFSTEANH 2026
CGG LS GV+LSP +P SY DC W G H+Q +
Sbjct: 526 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 577
Query: 2027 DFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNR----QGFKLAYQA 2082
D L + +G ++ ++ Q G LLS+ + + F + QGF L ++
Sbjct: 578 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 637
Query: 2083 YELQN-CPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYP 2139
+ CP+ PP + G+ S D G ++++C PGY L+G +LTCQ + +W+
Sbjct: 638 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL--SWSAA 695
Query: 2140 FPRCD--APCGYNVTSQNG--TIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE 2195
P C C NG T GFP + C+ PG+ +
Sbjct: 696 PPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCL------PGYSL---------- 739
Query: 2196 AVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQ 2255
+ + L +S +T + LK+
Sbjct: 740 -------------EGAAMLTCYSRDTGTPKWSDRVPKCALKY------------------ 768
Query: 2256 LKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
+ C P ++ G+ +++ C+ G+ L+G +TC Q+ P
Sbjct: 769 -EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 827
Query: 2316 CE 2317
C+
Sbjct: 828 CK 829
Score = 172 bits (437), Expect = 4e-42
Identities = 175/716 (24%), Positives = 269/716 (37%), Gaps = 86/716 (12%)
Query: 585 CFFNFTASSGIILSPNYPEEYGNNM---NCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
C N + G + SP+ + +C + I PG I + ++ + + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 642 KDDGISDIT--VLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECH 699
G + +L S L S + + L FQS G GF I Y + C
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 291
Query: 700 DPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPC 759
P P +G G + +FHCD G+ + QG E++ C L W+ P C A C
Sbjct: 292 FPPRPAHGDVSVTDLHPGGTATFHCDSGY-QLQGEETLIC-LNGTRPSWNGETPSCMASC 349
Query: 760 GGHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
GG + A+ G I+ P G +L C W+IEA G + + F+R + + D L VR G
Sbjct: 350 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 409
Query: 819 PASSSPLIGEYHGTQAPQ-FLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
+ SP+I + P+ LIS +Y+ ++ + + + +E+ E D C P
Sbjct: 410 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEA--FEEDRCFAP 467
Query: 878 GIPVNGHRHGG------DFGIRSTVTFSCDPGYTLSDDEP-----LVCERNHQWNHALPS 926
+ HG ++ + TFSC PGY L P V WN P+
Sbjct: 468 FL-----AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 522
Query: 927 CDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLL 986
C A+CGG + +G VLSP +P Y +C W + V K + + ++ L
Sbjct: 523 CKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 582
Query: 987 ITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISY----EGFNITFSEYD 1042
DG + +A+L G P + L L+F + +GF + F E
Sbjct: 583 FDGDGPSARVLAQLRG---PQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 639
Query: 1043 L-EPCDDPGVPAFSRRIGFHFGV--GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
+ C + P + R H + G LT+ C GY L G+ LTC WSA P
Sbjct: 640 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPP 697
Query: 1100 RCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK 1159
C +++ P N H G + R EG +
Sbjct: 698 AC------------QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAML 745
Query: 1160 VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
+D T W SD L Y C
Sbjct: 746 TCYSRD---------------------TGTPKW-------SDRVPKCALKYE-----PCL 772
Query: 1220 DPGIPNYGYRIRDEGHF-TDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
+PG+P GY+ + H+ + + C G+ + G T+TC+ G W P C
Sbjct: 773 NPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 160 bits (405), Expect = 2e-38
Identities = 196/791 (24%), Positives = 294/791 (37%), Gaps = 133/791 (16%)
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGK---ECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
C N++ G + SP+ P +C + + V P + I + ++ N+ + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 1509 YEGED--------SNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
G +NS ++G Q ++P N L L F+S GF I ++
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPT------NRLLLHFQSPRVPRGGGFRIHYQAY 286
Query: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
F P V TD G T T+ CDSGY++ ++ C+ G +PSW+ P
Sbjct: 287 LLSCGFPPRPAHGDVSV-TDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 343
Query: 1621 SCNAPCGGQ-YTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ------- 1672
SC A CGG + + G ++SP C + I + + F
Sbjct: 344 SCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 403
Query: 1673 -------TALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASAR 1725
+ L+ + D R L S + S E L +N +LL ++ R
Sbjct: 404 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 463
Query: 1726 GFH-FVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGS---TALH 1781
F F+ T+D E+ G++ F C PGY L+ A+
Sbjct: 464 CFAPFLAHGNVTTTDP----------------EYRPGALATFSCLPGYALEPPGPPNAIE 507
Query: 1782 CQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGI 1841
C V WNDT P+C C G ++ G +LSP +P+ Y +C+W + V E I
Sbjct: 508 C--VDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI 565
Query: 1842 QIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVA- 1900
+QV + D L + DG +A L G L S+ L L FQ+
Sbjct: 566 LLQV-EILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPN 624
Query: 1901 ---AAGFHLEYKTVGLA-ACQEPALPS---NSIKIGDRYMVNDVLSFQCEPGYTLQGRSH 1953
GF L +K V C E P + GD + VL++QCEPGY L G
Sbjct: 625 PGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTVLTYQCEPGYELLGSDI 683
Query: 1954 ISCMPGTVRRWNYPSPLC--IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 2011
++C W+ P C I TC PG N P+G
Sbjct: 684 LTCQWDL--SWSAAPPACQKIMTCAD--------------PGEIANGHRTASDAGFPVG- 726
Query: 2012 GAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQ 2071
+H+Q Y P G L A + T + D
Sbjct: 727 -SHVQ-------------------YRCLP------GYSLEGAAMLTCYSR------DTGT 754
Query: 2072 NRQGFKLAYQAYELQNCPDPPPFQNGY--MINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2129
+ ++ A + + C +P +NGY + Y G+S+ F CY G+ LIG +TC
Sbjct: 755 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 814
Query: 2130 HGINRNWNYPFPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWL---ITVPPGHGVY 2186
G W P C VT P E L I L + + G GVY
Sbjct: 815 PGHPSQWTSQPPLC------KVTQTT----DPSRQLEGGNLALAILLPLGLVIVLGSGVY 864
Query: 2187 INFTLLQTEAV 2197
I +T LQ +++
Sbjct: 865 IYYTKLQGKSL 875
Score = 139 bits (350), Expect = 5e-32
Identities = 155/573 (27%), Positives = 226/573 (39%), Gaps = 69/573 (12%)
Query: 32 CGGLVQGPNGTIESPGFPHGYP-----NYANCTWIIITGERNRIQLSFHTFALEEDFDIL 86
C + G +ESP G P +CT+ I I++ T L ++ ++L
Sbjct: 173 CNNNISEGEGYVESPDL--GSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 230
Query: 87 SVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILT-------LWFTTDFAVSAQGFKALYEV 139
+ G L RL SS++ G +L L F + GF+ Y+
Sbjct: 231 VLAGGGSP--GLAPRLLA---NSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 285
Query: 140 LPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
+CG P G + T + G + C GY L+G L C+ G SW+
Sbjct: 286 YLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL--NGTRPSWNGET 342
Query: 200 PFCRAEGACGGTL-RGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG 258
P C A +CGGT+ T I SP N C W I A G + L F L+E
Sbjct: 343 PSCMA--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED 400
Query: 259 YDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELK 318
D L + +P SPVI + D R +AQ
Sbjct: 401 NDRLMVRSGGSPL---------SPVIYDSD------MDDVPERGLISDAQ---------- 435
Query: 319 SRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCED 378
S V++L + +LS A D C P + R GA FSC
Sbjct: 436 SLYVELLSETPAN--PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLP 493
Query: 379 NYVLQ---GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
Y L+ +I C V T W+D P C+A CG L P+GV+ SP++P Y
Sbjct: 494 GYALEPPGPPNAIEC--VDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPG 550
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
CVW + + +K I L E + G D LT+ D G + VL L G ++
Sbjct: 551 QDCVWGVHVQE-EKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLL 606
Query: 496 SMSNQMWLHLQSDDSIGSP----GFKAVYQEIEKGG-CGDPGIPAYGKRTGS--SFLHGD 548
S + L Q+ +P GF ++E+ + C + P +G RT S + G
Sbjct: 607 SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGT 666
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
LT++C +EL+G ++TCQ + WS P+C
Sbjct: 667 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 699
Score = 136 bits (343), Expect = 3e-31
Identities = 164/689 (23%), Positives = 261/689 (37%), Gaps = 60/689 (8%)
Query: 2147 CGYNVTSQNGTIYSP--GFPDEYPI-LKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
C N++ G + SP G P + L DC + I V PG+G+ I L + + +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 2204 WDGPDQNSPQLG--VFSGNTAL---ETAYSSTNQVLLKFHSD-FSNGGFFVLNFHAFQLK 2257
G SP L + + ++ L + S TN++LL F S GG F +++ A+ L
Sbjct: 233 AGG---GSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS 289
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
C PP ++ D G + C GY L G + L C ++ + G P+C
Sbjct: 290 -CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Query: 2318 AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALE 2377
A C + + G I+SP G + TC W I+ + + + ++ D L
Sbjct: 347 ASC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 405
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCS 2434
V G S SP++ + + S + LY+ ++ + +R+ A C
Sbjct: 406 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 465
Query: 2435 LTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMV--GHSNATCRRNPLGMYQWDSLTPLCQ 2492
G+ + C PGY + G NA +P + W+ P C+
Sbjct: 466 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACK 524
Query: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATA------VCQEDGLWSN 2546
A+ CG S G ++ +C G ++ ++ V + D L
Sbjct: 525 AM-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLF 583
Query: 2547 KGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQAN 2606
G P+ + + AQL R + S + Q PG G
Sbjct: 584 DGDGPSAR------VLAQLRGPQPRRRLLSSGPDLTLQ--FQAPPGPPNPGL-------- 627
Query: 2607 GTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRECL 2664
G + + R +C L P G + + + G + C GY L+GS + C
Sbjct: 628 GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQ 687
Query: 2665 ANGLWSGSETRCLA-GHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC 2721
+ WS + C C P I NGH S GF V Y+C PG+ L G ++ C
Sbjct: 688 WDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTC 747
Query: 2722 LQDH----KWSGQTPVCVPI--TCGHPGNPAHGFTN--GSEFNLNDVVNFTCNTGYLLQG 2773
KWS + P C C +PG P +G+ + + + F C G+ L G
Sbjct: 748 YSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIG 807
Query: 2774 VSRAQCRSN--GQWSSPLPTCRVVNCSDP 2800
C QW+S P C+V +DP
Sbjct: 808 EVTITCVPGHPSQWTSQPPLCKVTQTTDP 836
Score = 124 bits (310), Expect = 2e-27
Identities = 146/598 (24%), Positives = 234/598 (39%), Gaps = 90/598 (15%)
Query: 208 CGGTLRGTSSSISSPHFPSEYENNA---DCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
C + + SP S DCT++I PG I + L + + L +
Sbjct: 173 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 232
Query: 265 SGTEAP----------SIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKA 314
+G +P S+ G L SP N L LHF S R GF +Q
Sbjct: 233 AGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPRVPRGGGFRIHYQAY-- 286
Query: 315 IELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQF 374
L S G P+ G V+D+ P G F
Sbjct: 287 --LLSCGFPPRPAH------------GDVSVTDLHP------------------GGTATF 314
Query: 375 SCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS-GVITSPNYPVQYE 433
C+ Y LQG +++ C + T +W+ P C A +CG + + G I SP
Sbjct: 315 HCDSGYQLQGEETLIC--LNGTRPSWNGETPSCMA-SCGGTIHNATLGRIVSPEPGGAVG 371
Query: 434 DNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDL 493
N C WVI + + + L FE L+ D L V G V+Y VP+
Sbjct: 372 PNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGS--PLSPVIYDSDMDDVPER 428
Query: 494 -IVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGK--RTGSSFLHGDTL 550
++S + +++ L S+ ++ E+ C P + A+G T + G
Sbjct: 429 GLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AHGNVTTTDPEYRPGALA 487
Query: 551 TFECPAAFELVGE---RVITCQQNNQ--WSGNKPSCVFSCFFNFTASSGIILSPNYPEEY 605
TF C + L I C + W+ +P+C C + +G++LSP++P+ Y
Sbjct: 488 TFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSY 547
Query: 606 GNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLA 665
+CVW + + RI L +V + D L + D VL G + +L
Sbjct: 548 SPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSARVLAQLRGPQPRRRLL 606
Query: 666 SSGHIVRLEFQS----DHSTTGRGFNITYTTFGQNE-CHDPGIPINGRR---FGDRFLLG 717
SSG + L+FQ+ + G+GF + + +N+ C + P G R GD + G
Sbjct: 607 SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRG 665
Query: 718 SSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE---------APCGGHLTAS 766
+ +++ C+ G+ + GS+ +TC ++ WS+ P C+ GH TAS
Sbjct: 666 TVLTYQCEPGY-ELLGSDILTC---QWDLSWSAAPPACQKIMTCADPGEIANGHRTAS 719
Score = 97.4 bits (241), Expect = 2e-19
Identities = 137/572 (23%), Positives = 201/572 (35%), Gaps = 112/572 (19%)
Query: 31 NCGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVY 89
+CGG + G I SP C W+I E R+ L F +L+ED D L V
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 407
Query: 90 DGQPQQGNLKVRLSGFQLPS-SIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
G + +P ++S L + ++ + +E C P
Sbjct: 408 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 467
Query: 149 GEILKGVLHGT------RFNIGDKIRYSCLPGYILEGHAILTCI--VSPGNGASWDFPAP 200
+ HG + G +SCLPGY LE I V P W+ P
Sbjct: 468 F-----LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE-PHWNDTEP 521
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYD 260
C+A CGG L + + SP +P Y DC W + + I L + EG D
Sbjct: 522 ACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-D 578
Query: 261 FLEISGTEAPSIW-LTGMNLPSP---VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
L + + PS L + P P ++SS L L F + G F +
Sbjct: 579 MLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH---- 634
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-GANVQFS 375
K +P +D CP+ PE G R S + G + +
Sbjct: 635 -----FKEVPR------------------NDTCPELPPPEWGWRTASHGDLIRGTVLTYQ 671
Query: 376 CEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
CE Y L GS +TCQ +WS P C+
Sbjct: 672 CEPGYELLGSDILTCQWDL----SWSAAPPACQK-------------------------- 701
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
++T DP E+ G+ T + DAG + L G
Sbjct: 702 -----IMTCADPG----------EIANGHRTAS--DAGFPVGSHVQYRCLPG-------Y 737
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQE--IEKGGCGDPGIPAYGKRT--GSSFLHGDTLT 551
S+ L S D+ G+P + + ++ C +PG+P G +T + G++L
Sbjct: 738 SLEGAAMLTCYSRDT-GTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 796
Query: 552 FECPAAFELVGERVITCQQN--NQWSGNKPSC 581
F C FEL+GE ITC +QW+ P C
Sbjct: 797 FFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 92.0 bits (227), Expect = 9e-18
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 15/184 (8%)
Query: 2684 PDPIVNGHISGDGFSYRDTVV-YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI-TCGH 2741
P P + G R TV+ YQC PG+ L+G+ + C D WS P C I TC
Sbjct: 648 PPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCAD 707
Query: 2742 PGNPAHGFTNGSE--FNLNDVVNFTCNTGYLLQGVSRAQCRSNG----QWSSPLPTC--R 2793
PG A+G S+ F + V + C GY L+G + C S +WS +P C +
Sbjct: 708 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 767
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRS 2851
C +PG EN Q + ++ G S+ + C +GF L+G +TC+ W
Sbjct: 768 YEPCLNPGVPENGY---QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 824
Query: 2852 LPKC 2855
P C
Sbjct: 825 PPLC 828
Score = 87.8 bits (216), Expect = 2e-16
Identities = 90/359 (25%), Positives = 143/359 (39%), Gaps = 41/359 (11%)
Query: 2928 AHGSRLGDD--FKTKSLLRFSCEMGHQLR--GSPERTCLLNGS---WSGLQPVCEAVSCG 2980
AHG+ D ++ +L FSC G+ L G P ++ + W+ +P C+A+ CG
Sbjct: 470 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM-CG 528
Query: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGY---------KTSGLMTRHCTANGTWTGTAP 3031
+ G+++S D S W + + L R + G P
Sbjct: 529 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGP 588
Query: 3032 DCTIIS-CGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 3090
+++ P + G D T + +Q PG + + K+ N +
Sbjct: 589 SARVLAQLRGPQPRRRLLSSGPDLT----LQFQAPPGPPNPGLGQGFVLHFKEVPRNDT- 643
Query: 3091 PVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEI 3148
CP+ PP + G T D G+ ++Y C GY+L S IL+C+ W
Sbjct: 644 -------CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP 696
Query: 3149 PQCLPVF-CGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT---- 3201
P C + C DPG A G S F S V ++C + L G++ C + T
Sbjct: 697 PACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPK 756
Query: 3202 WSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
WS P C + C +PG P G Q Y+ G ++ F C +G+ + G T TC+
Sbjct: 757 WSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 814
Score = 82.8 bits (203), Expect = 6e-15
Identities = 56/180 (31%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
Query: 2879 GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-- 2936
G V+ Y C L+G+D CQ D WS A P C C DPG A+G R D
Sbjct: 665 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAG 722
Query: 2937 FKTKSLLRFSCEMGHQLRGSPERTCLLNGS----WSGLQPVC--EAVSCGNPGTPTNG-M 2989
F S +++ C G+ L G+ TC + WS P C + C NPG P NG
Sbjct: 723 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 782
Query: 2990 IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN--GTWTGTAPDCTIISCGDPGTLANG 3047
+ S+ + C+EG++ G +T C WT P C + DP G
Sbjct: 783 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEG 842
Score = 82.4 bits (202), Expect = 7e-15
Identities = 132/589 (22%), Positives = 202/589 (34%), Gaps = 135/589 (22%)
Query: 2858 ISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSH--WSGALPHCTG 2915
+SCG P PA+ ++ G + C L G +T +C + W+G P C
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 347
Query: 2916 NNPGFC-----GDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL-------- 2962
+ G G +P G +G + + ++ + G +L ER L
Sbjct: 348 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAA--EGRRLHLHFERVSLDEDNDRLM 405
Query: 2963 LNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGI---LFSSSVIYACWEGYKTSGLMTRH 3019
+ S L PV + P G+I + + L S + +
Sbjct: 406 VRSGGSPLSPVIYDSDMDD--VPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 463
Query: 3020 C----TANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTS 3075
C A+G T T P+ PG LA ++ C PGY +E
Sbjct: 464 CFAPFLAHGNVTTTDPEYR------PGALA---------------TFSCLPGYALEPPGP 502
Query: 3076 AT-IRCTK--DGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSH 3132
I C + WN ++P CKA +C G V D+ S C+ G +
Sbjct: 503 PNAIECVDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQE 561
Query: 3133 SA--ILSCEGRGVWKGEI------------------------------PQCLPVFCGDPG 3160
+L E V +G++ P F PG
Sbjct: 562 EKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 621
Query: 3161 IPAEGRLSGKSFTYK-----------------------------SEVFFQCKSPFILVGS 3191
P G G +K + + +QC+ + L+GS
Sbjct: 622 PPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGS 681
Query: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS-RGYEVGSTVFFRCRKGYHI 3250
CQ D +WS P C TC DPG G + +S G+ VGS V +RC GY +
Sbjct: 682 DILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSL 739
Query: 3251 QGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF-------GYTLVYTC 3303
+G+ TC + T + ++ +P + E + V T G +L + C
Sbjct: 740 EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFC 799
Query: 3304 HPGFFLAGGSEHRTCKA--DMKWTGKSPVCKSKGVREVNETVTKTPVPS 3350
+ GF L G TC +WT + P+CK VT+T PS
Sbjct: 800 YEGFELI-GEVTITCVPGHPSQWTSQPPLCK----------VTQTTDPS 837
Score = 79.3 bits (194), Expect = 6e-14
Identities = 58/200 (29%), Positives = 87/200 (43%), Gaps = 12/200 (6%)
Query: 2978 SCGNPGTPTNGMIVSSDGILFSSSVI-YACWEGYKTSGLMTRHCTANGTWTGTAPDCT-I 3035
+C P G +S G L +V+ Y C GY+ G C + +W+ P C I
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 3036 ISCGDPGTLANGIQFGTD--FTFNKTVSYQCNPGYVMEAVTSATI--RCTKDGRWNPSKP 3091
++C DPG +ANG + +D F V Y+C PGY +E T R T +W+ P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 3092 VC--KAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSC--EGRGVWK 3145
C K C P +NG T+ ++ G S+ + C +G++L ++C W
Sbjct: 763 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 822
Query: 3146 GEIPQCLPVFCGDPGIPAEG 3165
+ P C DP EG
Sbjct: 823 SQPPLCKVTQTTDPSRQLEG 842
Score = 70.9 bits (172), Expect = 2e-11
Identities = 53/179 (29%), Positives = 72/179 (40%), Gaps = 12/179 (6%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI-SCGHPGVPANAVLTGE--LFT 2877
G + Y C+ G+ LLGS LTC + W + P C I +C PG AN T F
Sbjct: 665 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 724
Query: 2878 YGAVVHYSCRGSESLIGNDTRVCQE----DSHWSGALPHCTGNNPGFCGDPGTPAHG--S 2931
G+ V Y C SL G C WS +P C C +PG P +G +
Sbjct: 725 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEP-CLNPGVPENGYQT 783
Query: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN--GSWSGLQPVCEAVSCGNPGTPTNG 2988
++ LRF C G +L G TC+ W+ P+C+ +P G
Sbjct: 784 LYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEG 842
Score = 61.2 bits (147), Expect = 2e-08
Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 15/191 (7%)
Query: 2571 WRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC-RVISCGSLSFP 2629
WR S G + C PGY L G +L CQ + +W+ P+C ++++C
Sbjct: 654 WRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP--PACQKIMTCADPGEI 711
Query: 2630 PNGNKIGTLTVY--GATAIFTCNTGYTLVGSHVRECLANGL----WSGSETRCLAGH--C 2681
NG++ + + G+ + C GY+L G+ + C + WS +C + C
Sbjct: 712 ANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPC 771
Query: 2682 GSPDPIVNGHISGDGFSYR--DTVVYQCNPGFRLVGTSVRICLQDH--KWSGQTPVCVPI 2737
+P NG+ + Y+ +++ + C GF L+G C+ H +W+ Q P+C
Sbjct: 772 LNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVT 831
Query: 2738 TCGHPGNPAHG 2748
P G
Sbjct: 832 QTTDPSRQLEG 842
Score = 43.1 bits (100), Expect = 0.005
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ--WSSPLPTCRV 2794
++CG P PAHG + ++ + F C++GY LQG C + + W+ P+C +
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-M 346
Query: 2795 VNCSDPGFVENA 2806
+C G + NA
Sbjct: 347 ASCG--GTIHNA 356
Score = 33.9 bits (76), Expect = 3.0
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Query: 3035 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR--WNPSKPV 3092
++SCG P A+G TD T ++ C+ GY ++ T+ C R WN P
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQG--EETLICLNGTRPSWNGETPS 344
Query: 3093 CKA 3095
C A
Sbjct: 345 CMA 347
Score = 33.9 bits (76), Expect = 3.0
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGL---WDRSLPKCLAISCGHPGVPANAVL 2871
G + +HC G+ L G L C+ NG W+ P C+A SCG G NA L
Sbjct: 309 GGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA-SCG--GTIHNATL 358
Score = 33.1 bits (74), Expect = 5.1
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 3157 GDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT 3216
G PG+ A L+ S + +V + +L S RV + G Q + +
Sbjct: 236 GSPGL-APRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 289
Query: 3217 CPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL--ANLTWSGIQTECI 3272
C P P G S G T F C GY +QG T CL +W+G C+
Sbjct: 290 CGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Score = 33.1 bits (74), Expect = 5.1
Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 3468 QDPLNPDQDSSSHYHGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHE 3527
Q PL ++ G++A AIL+P +I+ G Y+Y + + K + H
Sbjct: 824 QPPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHS 883
Query: 3528 NS--NGQASFENPMYD 3541
S ++ F NP+Y+
Sbjct: 884 YSPITVESDFSNPLYE 899
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 226 bits (575), Expect = 4e-58
Identities = 166/535 (31%), Positives = 247/535 (46%), Gaps = 25/535 (4%)
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNH---ECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
C ++ EG + SP+ S +C Y I G GI ++ ++ L + + L V
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1162 DGKDSSSRPLGTFTKNELLG--LILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
G S + +LG +L S +N L L F + GF++ Y ++ L+ C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 1220 DPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECG 1279
P P +G + H T + C+ GY + G TL CL+G R W+ PSC+A CG
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFH-CDSGYQLQGEETLICLNGTRPSWNGETPSCMASCG 280
Query: 1280 GQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP 1339
G IH AT GRI+SP NL C W+IEA G+ + LHF + +D L V G
Sbjct: 281 GTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGG 340
Query: 1340 VDSDILLKEWSGSALPE-DIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMP 1398
++ + +PE + S SL ++ S+ + S++F C P +
Sbjct: 341 SPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLA 400
Query: 1399 Q-NGTRYGDSREAGDTVTFQCDPGYQLQGQA---KITCVQLNNRFFWQPDPPTCIAACGG 1454
N T G TF C PGY L+ I CV W P C A CGG
Sbjct: 401 HGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEP-HWNDTEPACKAMCGG 459
Query: 1455 NLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDS 1514
L+ PAGV+LSP++PQ Y PG++C W V V + I L + N+ D L +++G+
Sbjct: 460 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 518
Query: 1515 NSPLIGSYQGSQAPERIESSGNSLFLAFRS---DASVGL-SGFAIEFKEKPR-EACFDPG 1569
++ ++ +G Q R+ SSG L L F++ + GL GF + FKE PR + C +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELP 578
Query: 1570 NIMNGTRVGT--DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
G R + D G+ +TYQC+ GY++L +TC SW P+C
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 629
Score = 211 bits (537), Expect = 1e-53
Identities = 198/726 (27%), Positives = 303/726 (41%), Gaps = 101/726 (13%)
Query: 1801 VPCSGNFTQRRGTILSPGYPEPYGNNL---NCIWKIIVTEGSGIQIQVISFATEQNWDSL 1857
V C+ N ++ G + SP P L +C + I V G GI+IQV + Q + L
Sbjct: 101 VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 1858 EIHDGGDV-TAPRLGSFSGTTVPA-LLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAA 1915
+ GG APRL + S +L S +N+L LHFQS GF + Y+ L +
Sbjct: 161 VLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLS 219
Query: 1916 CQEPALPSNS-IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1974
C P P++ + + D + +F C+ GY LQG + C+ GT WN +P C+A+
Sbjct: 220 CGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMAS 278
Query: 1975 CGGTL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQ 2032
CGGT+ +TLG ++ SP G+ NL C W I G H+ F S + ++D L ++
Sbjct: 279 CGGTIHNATLGRIV-SPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 2033 NGPYHTSPMIGQFSGTDLPA-ALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
+G SP+I D+P L+S + S+ N L ++A+E C
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC-FA 396
Query: 2092 PPFQNGYMINSD--YSVGQSVSFECYPGYILI--GHP-VLTCQHGINRNWNYPFPRCDAP 2146
P +G + +D Y G +F C PGY L G P + C +WN P C A
Sbjct: 397 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM 456
Query: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIA 2202
CG ++ G + SP +P Y +DC+W + V + LLQ E +N D +
Sbjct: 457 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI-----LLQVEILNVREGDMLT 511
Query: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS-----DFSNGGFFVLNFHAFQLK 2257
++DG ++ L G SS + L+F + + G FVL+F ++
Sbjct: 512 LFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFK--EVP 569
Query: 2258 KCQPPPAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
+ P +P E D G + YQC PGY L+G+DILTC+ L + + P
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQW--DLSWSAAPP 627
Query: 2315 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFD 2374
C+ I++ PG N + S+ F
Sbjct: 628 ACQK--------------IMTCADPGEIANGHRTA-------------------SDAGFP 654
Query: 2375 ALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCS 2434
GS Q L ++ + +S D T K ++ P C+
Sbjct: 655 V-----GSHVQYRCL----------PGYSLEGAAMLTCYSRDTGTPKWSDRV----PKCA 695
Query: 2435 LTH-PLKNGGI-------LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 2486
L + P N G+ L + G + +FC G+ ++G TC P QW S
Sbjct: 696 LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTS 753
Query: 2487 LTPLCQ 2492
PLC+
Sbjct: 754 QPPLCK 759
Score = 208 bits (529), Expect = 9e-53
Identities = 159/557 (28%), Positives = 248/557 (44%), Gaps = 38/557 (6%)
Query: 1288 GRILSPGYPAPYDNNL---HCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDG--PVDS 1342
G + SP +P L CT+ I PG I + + ++L + G P +
Sbjct: 112 GYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLA 171
Query: 1343 DILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGT 1402
LL S + + S N L L F S GF I + + + C P P +G
Sbjct: 172 PRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS-CGFPPRPAHGD 230
Query: 1403 RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL-TGPAG 1461
G T TF CD GYQLQG+ + C+ R W + P+C+A+CGG + G
Sbjct: 231 VSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGETPSCMASCGGTIHNATLG 289
Query: 1462 VILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGS 1521
I+SP P C W ++ + L F+ +++ D L + G SP+I
Sbjct: 290 RIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYD 349
Query: 1522 YQGSQAPER-IESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDP----GNIMNGTR 1576
PER + S SL++ S+ ++ F+ + CF P GN+ T
Sbjct: 350 SDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNV---TT 406
Query: 1577 VGTDFKLGSTITYQCDSGYKILDP---SSITCVIGADGKPSWDQVLPSCNAPCGGQYTGS 1633
+++ G+ T+ C GY + P ++I CV + P W+ P+C A CGG+ +
Sbjct: 407 TDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE--PHWNDTEPACKAMCGGELSEP 464
Query: 1634 EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS 1693
GVVLSP++P +Y+ GQ C++ + V +E + Q D+ LFDG AR+L+
Sbjct: 465 AGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLA 524
Query: 1694 SLSGSHSGETLPLATSNQILLRFSAKSG----ASARGFHFVYQAVPRTSDTQCSSVPEPR 1749
L G L L++ + L+F A G +GF ++ VPR +DT C +P P
Sbjct: 525 QLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPR-NDT-CPELPPPE 581
Query: 1750 YGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC--VVPCS- 1804
+G R S + G+++ ++C PGY L GS L CQ W+ P+C ++ C+
Sbjct: 582 WGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD----LSWSAAPPACQKIMTCAD 637
Query: 1805 -GNFTQRRGTILSPGYP 1820
G T G+P
Sbjct: 638 PGEIANGHRTASDAGFP 654
Score = 187 bits (475), Expect = 2e-46
Identities = 188/743 (25%), Positives = 292/743 (39%), Gaps = 89/743 (11%)
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSL---HCEWIIEA 791
E+ T I+ V + T P C +++ G + P +L C + I
Sbjct: 82 ETTTTIITTTTVTTTVTSP---VLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHV 138
Query: 792 KPGHSIKITFDRFQTEVNYDTLEVRDG--PASSSPLIGEYHGTQAPQFLISTGNFMYLLF 849
PG+ I+I + L + G P + L+ Q L S N + L F
Sbjct: 139 YPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHF 198
Query: 850 TTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDD 909
+ GF IHY++ L SC P P +G D T TF CD GY L +
Sbjct: 199 QSPRVPRGGGFRIHYQAYLL---SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGE 255
Query: 910 EPLVCERNHQ--WNHALPSCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHG 966
E L+C + WN PSC A CGG I + G ++SP +L C W IE + G
Sbjct: 256 ETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEG 315
Query: 967 KGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFIS 1025
+ + + F L+ +D L++ GS PV + S + + GL + + + +S
Sbjct: 316 RRLHLHFERVSLDEDNDRLMVRSGGSPLSPV--IYDSDMDDVPERGLISDAQSLYVELLS 373
Query: 1026 DFSISYEGFNITFSEYDLEPCDDPGVPAFS-RRIGFHFGVGDSLTFSCFLGYRLEGA--- 1081
+ + ++ F ++ + C P + + + G TFSC GY LE
Sbjct: 374 ETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPP 433
Query: 1082 TKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGK 1141
+ C+ W+ P C A CG + G +LSP++P +Y +C++ + + K
Sbjct: 434 NAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEK 493
Query: 1142 GIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD 1201
I L+ + EGD L ++DG S+R L + +L+S + L L+F
Sbjct: 494 RILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPD-LTLQFQAPPGP 552
Query: 1202 TD----QGFQLTYTSFDL-VKCEDPGIPNYGYRIRDEGH-FTDTVVLYSCNPGYAMHGSN 1255
+ QGF L + C + P +G+R G TV+ Y C PGY + GS+
Sbjct: 553 PNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 612
Query: 1256 TLTC---LSGDRRVWDKPLPSC--IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIE 1310
LTC LS W P+C I C
Sbjct: 613 ILTCQWDLS-----WSAAPPACQKIMTC-------------------------------- 635
Query: 1311 ADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFD 1370
ADPG+ + H D PV S + + G +L ++ +
Sbjct: 636 ADPGEIANGHRTASDAGF----------PVGSHVQYRCLPGYSLEG------AAMLTCYS 679
Query: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQA 1428
D K + C +PG+P+NG T Y +AG+++ F C G++L G+
Sbjct: 680 RDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEV 739
Query: 1429 KITCVQLNNRFFWQPDPPTCIAA 1451
ITCV + W PP C A
Sbjct: 740 TITCVP-GHPSQWTSQPPLCKVA 761
Score = 178 bits (452), Expect = 7e-44
Identities = 154/585 (26%), Positives = 250/585 (42%), Gaps = 29/585 (4%)
Query: 384 GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY--PVQYEDNA-HCVW 440
G + T +T T + P+ C +N+ G + SP+ PV C +
Sbjct: 79 GEEETTTTIITTTTVTTTVTSPVL----CNNNISEGEGYVESPDLGSPVSRTLGLLDCTY 134
Query: 441 VITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQ 500
I P I++ + L + + L + G G +L + ++ S +N+
Sbjct: 135 SIHVY-PGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNR 193
Query: 501 MWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFEL 560
+ LH QS GF+ YQ CG P PA+G + + G T TF C + ++L
Sbjct: 194 LLLHFQSPRVPRGGGFRIHYQAYLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQL 252
Query: 561 VGERVITCQQNNQ--WSGNKPSCVFSCFFNF-TASSGIILSPNYPEEYGNNMNCVWLIIS 617
GE + C + W+G PSC+ SC A+ G I+SP G N+ C W+I +
Sbjct: 253 QGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEA 312
Query: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQ 676
G R+HL F ++ D L V+ G V+ ++VP + L S + +E
Sbjct: 313 AEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELL 372
Query: 677 SDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGD-RFLLGSSVSFHCDDGF-VKTQGS 734
S+ ++ + F ++ C P + D + G+ +F C G+ ++ G
Sbjct: 373 SETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGP 432
Query: 735 ESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPG 794
+ + W+ T P C+A CGG L+ +GV+L P WP Y C W + +
Sbjct: 433 PNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEE 492
Query: 795 HSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTT--- 851
I + + D L + DG S+ ++ + G Q + L+S+G + L F
Sbjct: 493 KRILLQVEILNVREG-DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 551
Query: 852 -DNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHG--GDFGIRSTV-TFSCDPGYTLS 907
N GF++H++ V +D+C + P G R GD IR TV T+ C+PGY L
Sbjct: 552 PPNPGLGQGFVLHFKEVP-RNDTCPELPPPEWGWRTASHGDL-IRGTVLTYQCEPGYELL 609
Query: 908 DDEPLVCERNHQWNHALPSCDAL--CG--GYIQGKSGTVLSPGFP 948
+ L C+ + W+ A P+C + C G I T GFP
Sbjct: 610 GSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Score = 178 bits (452), Expect = 7e-44
Identities = 177/722 (24%), Positives = 274/722 (37%), Gaps = 95/722 (13%)
Query: 1626 CGGQYTGSEGVVLSPNY--PHNYTAGQI-CLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
C + EG V SP+ P + T G + C YSI V + + Q + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1683 DGTHAQA---RLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
G + RLL++ S G+ L T N++LL F + GF YQA +
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT-NRLLLHFQSPRVPRGGGFRIHYQAYLLS-- 219
Query: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
C P P +G ++ G F C+ GY LQG L C + WN PSC
Sbjct: 220 --CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSC 275
Query: 1800 VVPCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLE 1858
+ C G G I+SP G NL C W I EG + + + +++ D L
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 1859 IHDGGDVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1917
+ GG +P + VP L S + LY+ S+ L ++ C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 1918 EPALPSNSIKIGD-RYMVNDVLSFQCEPGYTLQGR---SHISCMPGTVRRWNYPSPLCIA 1973
P L ++ D Y + +F C PGY L+ + I C+ T WN P C A
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKA 455
Query: 1974 TCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQ-------FLNFSTEANH 2026
CGG LS GV+LSP +P SY DC W G H+Q +
Sbjct: 456 MCGGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREG 507
Query: 2027 DFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNR----QGFKLAYQA 2082
D L + +G ++ ++ Q G LLS+ + + F + QGF L ++
Sbjct: 508 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 567
Query: 2083 YELQN-CPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYP 2139
+ CP+ PP + G+ S D G ++++C PGY L+G +LTCQ + +W+
Sbjct: 568 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL--SWSAA 625
Query: 2140 FPRCD--APCGYNVTSQNG--TIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE 2195
P C C NG T GFP + C+ PG+ +
Sbjct: 626 PPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCL------PGYSL---------- 669
Query: 2196 AVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQ 2255
+ + L +S +T + LK+
Sbjct: 670 -------------EGAAMLTCYSRDTGTPKWSDRVPKCALKY------------------ 698
Query: 2256 LKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
+ C P ++ G+ +++ C+ G+ L+G +TC Q+ P
Sbjct: 699 -EPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPL 757
Query: 2316 CE 2317
C+
Sbjct: 758 CK 759
Score = 172 bits (437), Expect = 4e-42
Identities = 175/716 (24%), Positives = 269/716 (37%), Gaps = 86/716 (12%)
Query: 585 CFFNFTASSGIILSPNYPEEYGNNM---NCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
C N + G + SP+ + +C + I PG I + ++ + + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 642 KDDGISDIT--VLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECH 699
G + +L S L S + + L FQS G GF I Y + C
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAY-LLSCG 221
Query: 700 DPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPC 759
P P +G G + +FHCD G+ + QG E++ C L W+ P C A C
Sbjct: 222 FPPRPAHGDVSVTDLHPGGTATFHCDSGY-QLQGEETLIC-LNGTRPSWNGETPSCMASC 279
Query: 760 GGHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDG 818
GG + A+ G I+ P G +L C W+IEA G + + F+R + + D L VR G
Sbjct: 280 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 339
Query: 819 PASSSPLIGEYHGTQAPQ-FLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
+ SP+I + P+ LIS +Y+ ++ + + + +E+ E D C P
Sbjct: 340 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEA--FEEDRCFAP 397
Query: 878 GIPVNGHRHGG------DFGIRSTVTFSCDPGYTLSDDEP-----LVCERNHQWNHALPS 926
+ HG ++ + TFSC PGY L P V WN P+
Sbjct: 398 FL-----AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 452
Query: 927 CDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLL 986
C A+CGG + +G VLSP +P Y +C W + V K + + ++ L
Sbjct: 453 CKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTL 512
Query: 987 ITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISY----EGFNITFSEYD 1042
DG + +A+L G P + L L+F + +GF + F E
Sbjct: 513 FDGDGPSARVLAQLRG---PQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 569
Query: 1043 L-EPCDDPGVPAFSRRIGFHFGV--GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
+ C + P + R H + G LT+ C GY L G+ LTC WSA P
Sbjct: 570 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD--LSWSAAPP 627
Query: 1100 RCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK 1159
C +++ P N H G + R EG +
Sbjct: 628 AC------------QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAML 675
Query: 1160 VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCE 1219
+D T W SD L Y C
Sbjct: 676 TCYSRD---------------------TGTPKW-------SDRVPKCALKYE-----PCL 702
Query: 1220 DPGIPNYGYRIRDEGHF-TDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
+PG+P GY+ + H+ + + C G+ + G T+TC+ G W P C
Sbjct: 703 NPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 160 bits (404), Expect = 3e-38
Identities = 196/796 (24%), Positives = 295/796 (37%), Gaps = 130/796 (16%)
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGK---ECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
C N++ G + SP+ P +C + + V P + I + ++ N+ + L +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 1509 YEGED--------SNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEK 1560
G +NS ++G Q ++P N L L F+S GF I ++
Sbjct: 163 AGGGSPGLAPRLLANSSMLGEGQVLRSPT------NRLLLHFQSPRVPRGGGFRIHYQAY 216
Query: 1561 PREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
F P V TD G T T+ CDSGY++ ++ C+ G +PSW+ P
Sbjct: 217 LLSCGFPPRPAHGDVSV-TDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETP 273
Query: 1621 SCNAPCGGQ-YTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ------- 1672
SC A CGG + + G ++SP C + I + + F
Sbjct: 274 SCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 333
Query: 1673 -------TALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASAR 1725
+ L+ + D R L S + S E L +N +LL ++ R
Sbjct: 334 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 393
Query: 1726 GFH-FVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGS---TALH 1781
F F+ T+D E+ G++ F C PGY L+ A+
Sbjct: 394 CFAPFLAHGNVTTTDP----------------EYRPGALATFSCLPGYALEPPGPPNAIE 437
Query: 1782 CQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGI 1841
C V WNDT P+C C G ++ G +LSP +P+ Y +C+W + V E I
Sbjct: 438 C--VDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI 495
Query: 1842 QIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVA- 1900
+QV + D L + DG +A L G L S+ L L FQ+
Sbjct: 496 LLQV-EILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPN 554
Query: 1901 ---AAGFHLEYKTVGLA-ACQEPALPS---NSIKIGDRYMVNDVLSFQCEPGYTLQGRSH 1953
GF L +K V C E P + GD + VL++QCEPGY L G
Sbjct: 555 PGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTVLTYQCEPGYELLGSDI 613
Query: 1954 ISCMPGTVRRWNYPSPLC--IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 2011
++C W+ P C I TC PG N P+G
Sbjct: 614 LTCQWDL--SWSAAPPACQKIMTCAD--------------PGEIANGHRTASDAGFPVG- 656
Query: 2012 GAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQ 2071
+H+Q Y P G L A + T + D
Sbjct: 657 -SHVQ-------------------YRCLP------GYSLEGAAMLTCYSR------DTGT 684
Query: 2072 NRQGFKLAYQAYELQNCPDPPPFQNGY--MINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2129
+ ++ A + + C +P +NGY + Y G+S+ F CY G+ LIG +TC
Sbjct: 685 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Query: 2130 HGINRNWNYPFPRCDAPCGYNVTSQNGTI-----YSPGFPDEYPILKDCIWL---ITVPP 2181
G W P C Y N + P E L I L + +
Sbjct: 745 PGHPSQWTSQPPLCKV--AYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVL 802
Query: 2182 GHGVYINFTLLQTEAV 2197
G GVYI +T LQ +++
Sbjct: 803 GSGVYIYYTKLQGKSL 818
Score = 139 bits (350), Expect = 5e-32
Identities = 155/573 (27%), Positives = 226/573 (39%), Gaps = 69/573 (12%)
Query: 32 CGGLVQGPNGTIESPGFPHGYP-----NYANCTWIIITGERNRIQLSFHTFALEEDFDIL 86
C + G +ESP G P +CT+ I I++ T L ++ ++L
Sbjct: 103 CNNNISEGEGYVESPDL--GSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELL 160
Query: 87 SVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILT-------LWFTTDFAVSAQGFKALYEV 139
+ G L RL SS++ G +L L F + GF+ Y+
Sbjct: 161 VLAGGGSP--GLAPRLLA---NSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 140 LPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
+CG P G + T + G + C GY L+G L C+ G SW+
Sbjct: 216 YLL-SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL--NGTRPSWNGET 272
Query: 200 PFCRAEGACGGTL-RGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG 258
P C A +CGGT+ T I SP N C W I A G + L F L+E
Sbjct: 273 PSCMA--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED 330
Query: 259 YDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELK 318
D L + +P SPVI + D R +AQ
Sbjct: 331 NDRLMVRSGGSPL---------SPVIYDSD------MDDVPERGLISDAQ---------- 365
Query: 319 SRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCED 378
S V++L + +LS A D C P + R GA FSC
Sbjct: 366 SLYVELLSETPAN--PLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLP 423
Query: 379 NYVLQ---GSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
Y L+ +I C V T W+D P C+A CG L P+GV+ SP++P Y
Sbjct: 424 GYALEPPGPPNAIEC--VDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPG 480
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
CVW + + +K I L E + G D LT+ D G + VL L G ++
Sbjct: 481 QDCVWGVHVQE-EKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLL 536
Query: 496 SMSNQMWLHLQSDDSIGSP----GFKAVYQEIEKGG-CGDPGIPAYGKRTGS--SFLHGD 548
S + L Q+ +P GF ++E+ + C + P +G RT S + G
Sbjct: 537 SSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGT 596
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
LT++C +EL+G ++TCQ + WS P+C
Sbjct: 597 VLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 629
Score = 131 bits (330), Expect = 1e-29
Identities = 162/683 (23%), Positives = 258/683 (37%), Gaps = 60/683 (8%)
Query: 2147 CGYNVTSQNGTIYSP--GFPDEYPI-LKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
C N++ G + SP G P + L DC + I V PG+G+ I L + + +
Sbjct: 103 CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVL 162
Query: 2204 WDGPDQNSPQLG--VFSGNTAL---ETAYSSTNQVLLKFHSD-FSNGGFFVLNFHAFQLK 2257
G SP L + + ++ L + S TN++LL F S GG F +++ A+ L
Sbjct: 163 AGG---GSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLLS 219
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
C PP ++ D G + C GY L G + L C ++ + G P+C
Sbjct: 220 -CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 2318 AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALE 2377
A C + + G I+SP G + TC W I+ + + + ++ D L
Sbjct: 277 ASC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PYCS 2434
V G S SP++ + + S + LY+ ++ + +R+ A C
Sbjct: 336 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 395
Query: 2435 LTHPLKNGGILNRTAGAVGSKVHYFCKPGYRM--VGHSNATCRRNPLGMYQWDSLTPLCQ 2492
G+ + C PGY + G NA +P + W+ P C+
Sbjct: 396 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPACK 454
Query: 2493 AVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ------QATAVCQEDGLWSN 2546
A+ CG S G ++ +C G ++ + + V + D L
Sbjct: 455 AM-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLF 513
Query: 2547 KGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQAN 2606
G P+ + + AQL R + S + Q PG G
Sbjct: 514 DGDGPSAR------VLAQLRGPQPRRRLLSSGPDLTLQ--FQAPPGPPNPGL-------- 557
Query: 2607 GTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRECL 2664
G + + R +C L P G + + + G + C GY L+GS + C
Sbjct: 558 GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQ 617
Query: 2665 ANGLWSGSETRC-LAGHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC 2721
+ WS + C C P I NGH S GF V Y+C PG+ L G ++ C
Sbjct: 618 WDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTC 677
Query: 2722 LQ----DHKWSGQTPVCV--PITCGHPGNPAHGFTN--GSEFNLNDVVNFTCNTGYLLQG 2773
KWS + P C C +PG P +G+ + + + F C G+ L G
Sbjct: 678 YSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIG 737
Query: 2774 VSRAQCRSN--GQWSSPLPTCRV 2794
C QW+S P C+V
Sbjct: 738 EVTITCVPGHPSQWTSQPPLCKV 760
Score = 127 bits (319), Expect = 2e-28
Identities = 206/918 (22%), Positives = 317/918 (34%), Gaps = 169/918 (18%)
Query: 138 EVLPSHTCGNP---GEILKGVLHGTRFNIGDKIRYSCLPGYILE---GHAILTCIVSPGN 191
E+LP P E L +LHG G ++ Y LPG L G T +
Sbjct: 34 EILPEPGSETPTVASEALAELLHGALLRRGPEMGY--LPGPPLGPEGGEEETTTTIITTT 91
Query: 192 GASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNA---DCTWTILAEPGDTIAL 248
+ +P C + + SP S DCT++I PG I +
Sbjct: 92 TVTTTVTSPVL-----CNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEI 146
Query: 249 VFTDFQLEEGYDFLEISGTEAP----------SIWLTGMNLPSPVISSKNWLRLHFTSDS 298
L + + L ++G +P S+ G L SP N L LHF S
Sbjct: 147 QVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPT----NRLLLHFQSPR 202
Query: 299 NHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENG 358
R GF +Q L S G P+ G V+D+ P
Sbjct: 203 VPRGGGFRIHYQAY----LLSCGFPPRPAH------------GDVSVTDLHP-------- 238
Query: 359 RRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRG 418
G F C+ Y LQG +++ C + T +W+ P C A +CG +
Sbjct: 239 ----------GGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSCMA-SCGGTIHN 285
Query: 419 PS-GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGD 477
+ G I SP N C WVI + + + L FE L+ D L V G
Sbjct: 286 ATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRLMVRSGGS--P 342
Query: 478 TRSVLYVLTGSSVPDL-IVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAY 536
V+Y VP+ ++S + +++ L S+ ++ E+ C P + A+
Sbjct: 343 LSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL-AH 401
Query: 537 GK--RTGSSFLHGDTLTFECPAAFELVGE---RVITCQQNNQ--WSGNKPSCVFSCFFNF 589
G T + G TF C + L I C + W+ +P+C C
Sbjct: 402 GNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGEL 461
Query: 590 TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDI 649
+ +G++LSP++P+ Y +CVW + + RI L +V + D L + D
Sbjct: 462 SEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDMLTLFDGDGPSA 520
Query: 650 TVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRR 709
VL G + +L SSG + L+FQ+ PG P G
Sbjct: 521 RVLAQLRGPQPRRRLLSSGPDLTLQFQAP----------------------PGPPNPG-- 556
Query: 710 FGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGV 769
LG H + V + T P P G TAS G
Sbjct: 557 ------LGQGFVLHFKE-------------------VPRNDTCPELPPPEWGWRTASHGD 591
Query: 770 IL---------PPGWPGYYKDSLHCEWIIE--AKPGHSIKITFDRFQTEVNYDTLEVRDG 818
++ PG+ D L C+W + A P KI D E+ +G
Sbjct: 592 LIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM-------TCADPGEIANG 644
Query: 819 PASSSPL---IGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCL 875
++S +G + + G M ++ D + L+ + CL
Sbjct: 645 HRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV--PKCALKYEPCL 702
Query: 876 DPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNH--QWNHALPSCDALC 931
+PG+P NG++ + + ++ F C G+ L + + C H QW P C
Sbjct: 703 NPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAY 762
Query: 932 GGYIQGKSGTVLSPGFPDFYPNSLNCTWTI------EVSHGKGVQMIF------HTFHLE 979
+ + V P N I + G GV + + F
Sbjct: 763 EELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFS 822
Query: 980 SSHDYLLITEDGSFSEPV 997
SH Y IT + FS P+
Sbjct: 823 GSHSYSPITVESDFSNPL 840
Score = 97.4 bits (241), Expect = 2e-19
Identities = 137/572 (23%), Positives = 201/572 (35%), Gaps = 112/572 (19%)
Query: 31 NCGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVY 89
+CGG + G I SP C W+I E R+ L F +L+ED D L V
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 337
Query: 90 DGQPQQGNLKVRLSGFQLPS-SIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
G + +P ++S L + ++ + +E C P
Sbjct: 338 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 397
Query: 149 GEILKGVLHGT------RFNIGDKIRYSCLPGYILEGHAILTCI--VSPGNGASWDFPAP 200
+ HG + G +SCLPGY LE I V P W+ P
Sbjct: 398 F-----LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE-PHWNDTEP 451
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYD 260
C+A CGG L + + SP +P Y DC W + + I L + EG D
Sbjct: 452 ACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-D 508
Query: 261 FLEISGTEAPSIW-LTGMNLPSP---VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
L + + PS L + P P ++SS L L F + G F +
Sbjct: 509 MLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH---- 564
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-GANVQFS 375
K +P +D CP+ PE G R S + G + +
Sbjct: 565 -----FKEVPR------------------NDTCPELPPPEWGWRTASHGDLIRGTVLTYQ 601
Query: 376 CEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
CE Y L GS +TCQ +WS P C+
Sbjct: 602 CEPGYELLGSDILTCQWDL----SWSAAPPACQK-------------------------- 631
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
++T DP E+ G+ T + DAG + L G
Sbjct: 632 -----IMTCADPG----------EIANGHRTAS--DAGFPVGSHVQYRCLPG-------Y 667
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQE--IEKGGCGDPGIPAYGKRT--GSSFLHGDTLT 551
S+ L S D+ G+P + + ++ C +PG+P G +T + G++L
Sbjct: 668 SLEGAAMLTCYSRDT-GTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 726
Query: 552 FECPAAFELVGERVITCQQN--NQWSGNKPSC 581
F C FEL+GE ITC +QW+ P C
Sbjct: 727 FFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 92.0 bits (227), Expect = 9e-18
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 15/184 (8%)
Query: 2684 PDPIVNGHISGDGFSYRDTVV-YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI-TCGH 2741
P P + G R TV+ YQC PG+ L+G+ + C D WS P C I TC
Sbjct: 578 PPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCAD 637
Query: 2742 PGNPAHGFTNGSE--FNLNDVVNFTCNTGYLLQGVSRAQCRSNG----QWSSPLPTC--R 2793
PG A+G S+ F + V + C GY L+G + C S +WS +P C +
Sbjct: 638 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 697
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRS 2851
C +PG EN Q + ++ G S+ + C +GF L+G +TC+ W
Sbjct: 698 YEPCLNPGVPENGY---QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 754
Query: 2852 LPKC 2855
P C
Sbjct: 755 PPLC 758
Score = 87.8 bits (216), Expect = 2e-16
Identities = 90/359 (25%), Positives = 143/359 (39%), Gaps = 41/359 (11%)
Query: 2928 AHGSRLGDD--FKTKSLLRFSCEMGHQLR--GSPERTCLLNGS---WSGLQPVCEAVSCG 2980
AHG+ D ++ +L FSC G+ L G P ++ + W+ +P C+A+ CG
Sbjct: 400 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM-CG 458
Query: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGY---------KTSGLMTRHCTANGTWTGTAP 3031
+ G+++S D S W + + L R + G P
Sbjct: 459 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGP 518
Query: 3032 DCTIIS-CGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 3090
+++ P + G D T + +Q PG + + K+ N +
Sbjct: 519 SARVLAQLRGPQPRRRLLSSGPDLT----LQFQAPPGPPNPGLGQGFVLHFKEVPRNDT- 573
Query: 3091 PVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEI 3148
CP+ PP + G T D G+ ++Y C GY+L S IL+C+ W
Sbjct: 574 -------CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP 626
Query: 3149 PQCLPVF-CGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT---- 3201
P C + C DPG A G S F S V ++C + L G++ C + T
Sbjct: 627 PACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPK 686
Query: 3202 WSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
WS P C + C +PG P G Q Y+ G ++ F C +G+ + G T TC+
Sbjct: 687 WSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Score = 82.0 bits (201), Expect = 9e-15
Identities = 127/571 (22%), Positives = 196/571 (34%), Gaps = 125/571 (21%)
Query: 2858 ISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSH--WSGALPHCTG 2915
+SCG P PA+ ++ G + C L G +T +C + W+G P C
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 277
Query: 2916 NNPGFC-----GDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL-------- 2962
+ G G +P G +G + + ++ + G +L ER L
Sbjct: 278 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAA--EGRRLHLHFERVSLDEDNDRLM 335
Query: 2963 LNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGI---LFSSSVIYACWEGYKTSGLMTRH 3019
+ S L PV + P G+I + + L S + +
Sbjct: 336 VRSGGSPLSPVIYDSDMDD--VPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 393
Query: 3020 C----TANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTS 3075
C A+G T T P+ PG LA ++ C PGY +E
Sbjct: 394 CFAPFLAHGNVTTTDPEYR------PGALA---------------TFSCLPGYALEPPGP 432
Query: 3076 AT-IRCTK--DGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSH 3132
I C + WN ++P CKA +C G V D+ S C+ G +
Sbjct: 433 PNAIECVDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQE 491
Query: 3133 SA--ILSCEGRGVWKGEI------------------------------PQCLPVFCGDPG 3160
+L E V +G++ P F PG
Sbjct: 492 EKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 551
Query: 3161 IPAEGRLSGKSFTYK-----------------------------SEVFFQCKSPFILVGS 3191
P G G +K + + +QC+ + L+GS
Sbjct: 552 PPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGS 611
Query: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS-RGYEVGSTVFFRCRKGYHI 3250
CQ D +WS P C TC DPG G + +S G+ VGS V +RC GY +
Sbjct: 612 DILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSL 669
Query: 3251 QGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF-------GYTLVYTC 3303
+G+ TC + T + ++ +P + E + V T G +L + C
Sbjct: 670 EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFC 729
Query: 3304 HPGFFLAGGSEHRTCKA--DMKWTGKSPVCK 3332
+ GF L G TC +WT + P+CK
Sbjct: 730 YEGFELI-GEVTITCVPGHPSQWTSQPPLCK 759
Score = 78.6 bits (192), Expect = 1e-13
Identities = 53/168 (31%), Positives = 72/168 (42%), Gaps = 13/168 (7%)
Query: 2879 GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-- 2936
G V+ Y C L+G+D CQ D WS A P C C DPG A+G R D
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAG 652
Query: 2937 FKTKSLLRFSCEMGHQLRGSPERTCLLNGS----WSGLQPVC--EAVSCGNPGTPTNG-M 2989
F S +++ C G+ L G+ TC + WS P C + C NPG P NG
Sbjct: 653 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 712
Query: 2990 IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN--GTWTGTAPDCTI 3035
+ S+ + C+EG++ G +T C WT P C +
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 760
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/166 (30%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI-SCGHPGVPANAVLTGE--LFT 2877
G + Y C+ G+ LLGS LTC + W + P C I +C PG AN T F
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Query: 2878 YGAVVHYSCRGSESLIGNDTRVCQE----DSHWSGALPHCTGNNPGFCGDPGTPAHG--S 2931
G+ V Y C SL G C WS +P C C +PG P +G +
Sbjct: 655 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEP-CLNPGVPENGYQT 713
Query: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN--GSWSGLQPVCE 2975
++ LRF C G +L G TC+ W+ P+C+
Sbjct: 714 LYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 759
Score = 48.1 bits (113), Expect = 2e-04
Identities = 43/143 (30%), Positives = 58/143 (40%), Gaps = 19/143 (13%)
Query: 1046 CDDPGVPAFSRRIGFHFG--VGDSLTFSCFLGYRLEGATKLTCLG--GGRRVWSAPLPRC 1101
C DPG A R G VG + + C GY LEGA LTC G WS +P+C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 1102 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRT-RSFQLFEGDTLKV 1160
+ L+P P +N ++ +YK +AG+ + F+L T+
Sbjct: 695 ALK--------YEPCLNPGVP---ENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC 743
Query: 1161 YDGKDS---SSRPLGTFTKNELL 1180
G S S PL ELL
Sbjct: 744 VPGHPSQWTSQPPLCKVAYEELL 766
Score = 43.1 bits (100), Expect = 0.005
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ--WSSPLPTCRV 2794
++CG P PAHG + ++ + F C++GY LQG C + + W+ P+C +
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-M 276
Query: 2795 VNCSDPGFVENA 2806
+C G + NA
Sbjct: 277 ASCG--GTIHNA 286
Score = 33.9 bits (76), Expect = 3.0
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Query: 3035 IISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR--WNPSKPV 3092
++SCG P A+G TD T ++ C+ GY ++ T+ C R WN P
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQG--EETLICLNGTRPSWNGETPS 274
Query: 3093 CKA 3095
C A
Sbjct: 275 CMA 277
Score = 33.9 bits (76), Expect = 3.0
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGL---WDRSLPKCLAISCGHPGVPANAVL 2871
G + +HC G+ L G L C+ NG W+ P C+A SCG G NA L
Sbjct: 239 GGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA-SCG--GTIHNATL 288
Score = 33.1 bits (74), Expect = 5.1
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 9/118 (7%)
Query: 3157 GDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT 3216
G PG+ A L+ S + +V + +L S RV + G Q + +
Sbjct: 166 GSPGL-APRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQAYLL-----S 219
Query: 3217 CPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL--ANLTWSGIQTECI 3272
C P P G S G T F C GY +QG T CL +W+G C+
Sbjct: 220 CGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 32.3 bits (72), Expect = 8.6
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 3487 GSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENS--NGQASFENPMYD 3541
G++A AIL+P +I+ G Y+Y + + K + H S ++ F NP+Y+
Sbjct: 786 GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYE 842
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 214 bits (545), Expect = 1e-54
Identities = 169/648 (26%), Positives = 282/648 (43%), Gaps = 127/648 (19%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G+ + G I SP YP+ Y + C+W+I V+EG + + +F E++ +D LE
Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
+ DG + +G F G P + S+SN+L++ F SD S+ AGF + E
Sbjct: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF----FKEVDE 579
Query: 1919 PALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCG 1976
+ P + + VN + S++C +PGY L +C CG
Sbjct: 580 CSWPDHGGC--EHRCVNTLGSYKCACDPGYELAA----------------DKKMCEVACG 621
Query: 1977 GTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEIQ 2032
G ++ L G I SPG+P YP N +C W++ P Y +QF F E N +DF+E++
Sbjct: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
Query: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPP 2092
+G + + G+F G++ P + S ++ + F SD++ +++GF+ + + + + D
Sbjct: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD-- 739
Query: 2093 PFQNGYMINSDYSVGQSVSFECYPGYIL--IGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
NG + + S C GY L GH C+ +A C +
Sbjct: 740 ---NGGCQHECVNTFGSYLCRCRNGYWLHENGH---DCK--------------EAGCAHK 779
Query: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDYIAVWDG 2206
++S GT+ SP +PD+YP ++C W I+ GH V + F + E D++ ++DG
Sbjct: 780 ISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDG 839
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVP 2266
PD +P LG F G+ + +S + + L+F+SD S Q K Q +
Sbjct: 840 PDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDAS-----------VQRKGFQAVHST- 887
Query: 2267 QAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
E G +K ++ T +L S QF + EA+C
Sbjct: 888 -----------ECGGRLK-----------AEVQTKELYSHAQFGDNNYPSEARC------ 919
Query: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGS 2382
W I E Y + + TF+ E++ +D +E +DG
Sbjct: 920 ----------------------DWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGY 957
Query: 2383 SGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
+P L G+ + + S + L +R+ TD +KKGF RY +
Sbjct: 958 DSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 204 bits (520), Expect = 1e-51
Identities = 172/650 (26%), Positives = 275/650 (42%), Gaps = 126/650 (19%)
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
A CGG ++ +G+I SP YP Y + C W I G + L F F+ E A+D
Sbjct: 462 ATCGGDMNK-DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
L+V DGP + L+ + G PED+ S+ N L ++F SD I+K+GF+ F +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV--- 577
Query: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
++ P +G + CDPGY+L K+ C A
Sbjct: 578 -DECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-----------------CEVA 619
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFLH 1507
CGG +T G I SP +P+ YP K C W+V + I+L F+ F +E + YDF+
Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
Query: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD 1567
+ G ++ L G + GS+ PE I S N++ + F+SD +V GF F E D
Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
Query: 1568 PGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCG 1627
G + V T GS + +C +GY + + G D K A C
Sbjct: 740 NGGCQHEC-VNT---FGSYLC-RCRNGYWLHEN-------GHDCK----------EAGCA 777
Query: 1628 GQYTGSEGVVLSPNYPHNYTAGQICLYSITVP---KEFVVFGQF--AYFQTALNDLAELF 1682
+ + EG + SPN+P Y + + C ++I+ + + F +F Q D E++
Sbjct: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
Query: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQC 1742
DG + A +L GS + +A+ + + LRF + + +GF V+ T+C
Sbjct: 838 DGPDSLAPILGRFCGSKKPDP-TVASGSSMFLRFYSDASVQRKGFQAVH-------STEC 889
Query: 1743 SSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVP 1802
G R+ +E + + AQ+ D
Sbjct: 890 --------GGRLKAEVQTKELY-----------------------SHAQFGDN------- 911
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQ----NWDSLE 1858
YP + C W I+ +G G+++ +F E+ +D +E
Sbjct: 912 ---------------NYP----SEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYME 952
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY 1908
+DG D +APRLG F G+ + S + L + F++D ++ GFH Y
Sbjct: 953 AYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
Score = 197 bits (502), Expect = 1e-49
Identities = 176/661 (26%), Positives = 274/661 (41%), Gaps = 123/661 (18%)
Query: 745 NVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRF 804
N++ EA CGG + +G I P +P Y+ S C W I G + +TF F
Sbjct: 450 NILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAF 509
Query: 805 QTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGF 860
+ E + YD LEVRDGP S LIG + G + P+ + S+ N +++ F +D S + GF
Sbjct: 510 EIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF 569
Query: 861 LIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQW 920
++ E D C P HR G + +CDPGY L+ D+ +
Sbjct: 570 AANFFK---EVDECSWPDHGGCEHRCVNTLG---SYKCACDPGYELAADKKM-------- 615
Query: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
C+ CGG+I +GT+ SPG+P YP + NC W + + + F F LE
Sbjct: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
Query: 981 S----HDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFN 1035
+ +D++ + S + R GS P I + + ++ F SD ++S GF
Sbjct: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS---QSNNMRVEFKSDNTVSKRGFR 726
Query: 1036 ITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWS 1095
F E D G FG S C GY L C G
Sbjct: 727 AHFFSDKDECAKDNG--GCQHECVNTFG---SYLCRCRNGYWLH-ENGHDCKEAG----- 775
Query: 1096 APLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
C + EGTL SPN+P Y + EC + I + AG + L F++ +
Sbjct: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
Query: 1156 -----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
D L++YDG DS + LG F ++ + S S+ ++L F ++ S +GFQ +
Sbjct: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
Query: 1211 TSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKP 1270
++ +C G R++ E T LYS +A G N
Sbjct: 886 ST----EC--------GGRLKAE---VQTKELYS----HAQFGDNN-------------- 912
Query: 1271 LPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE--- 1327
Y + C W+I A+ G + L F F+ E
Sbjct: 913 ----------------------------YPSEARCDWVIVAEDGYGVELTFRTFEVEEEA 944
Query: 1328 -MAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFST 1386
+D ++ +DG S L + GS E+I+S +SL ++F +D I+K GF ++++
Sbjct: 945 DCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Query: 1387 S 1387
+
Sbjct: 1005 T 1005
Score = 197 bits (501), Expect = 2e-49
Identities = 138/463 (29%), Positives = 218/463 (47%), Gaps = 57/463 (12%)
Query: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDT 466
TCG ++ +G I SPNYP Y + CVW IT ++ V L F+ FE+ER YD
Sbjct: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHV-GLTFQAFEIERHDSCAYDY 521
Query: 467 LTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKA-VYQEIEK 525
L V D + +++ G P+ + S SN++W+ SD SI GF A ++E+++
Sbjct: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
Query: 526 GGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
D G G +TL G C + + +K C +C
Sbjct: 580 CSWPDHG--------GCEHRCVNTL-----------GSYKCACDPGYELAADKKMCEVAC 620
Query: 586 FFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLAV 641
T +G I SP +P+EY N NCVW +++ RI L F F++E ++DF+ V
Sbjct: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
Query: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDP 701
+ D + G F G+E P + S + +R+EF+SD++ + RGF + + ++EC
Sbjct: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAKD 739
Query: 702 GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGG 761
NG C V T G S C ++G + + EA C
Sbjct: 740 ----NG---------------GCQHECVNTFG--SYLCRCRNGYWLHENGHDCKEAGCAH 778
Query: 762 HLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YDTLEVRD 817
+++ G + P WP Y C W I + GH +K+TF+ F+ E + YD LE+ D
Sbjct: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
Query: 818 GPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGF 860
GP S +P++G + G++ P +++G+ M+L F +D S GF
Sbjct: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 190 bits (483), Expect = 2e-47
Identities = 164/637 (25%), Positives = 258/637 (40%), Gaps = 128/637 (20%)
Query: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
A CGG G + SPNYP +Y + C++ ITV + F V F F+ + D
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTS 1738
E+ DG ++ L+ G E + ++SN++ ++F + + GF +
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 1739 DTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPS 1798
E R +GS A C+PGY L +
Sbjct: 581 SWPDHGGCEHRCVNTLGSYKCA-------CDPGYELAADKKM------------------ 615
Query: 1799 CVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----W 1854
C V C G T+ GTI SPG+P+ Y N NC+W+++ I +Q F E N +
Sbjct: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
Query: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
D +E+ G A G F G+ P ++ S SN + + F+SD +V+ GF + +
Sbjct: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF----FS 731
Query: 1915 ACQEPALPSNSIKIGDRYMVNDVLSF--QCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
E A + + VN S+ +C GY L H C
Sbjct: 732 DKDECAKDNGGCQ---HECVNTFGSYLCRCRNGYWLHENGH-DCKE-------------- 773
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
A C +S++ G + SP +P YP+ +CTW IS G+ + F F E + +D
Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
LE+ +GP +P++G+F G+ P +++ + FYSD S R+GF QA C
Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF----QAVHSTEC 889
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPF-PRCDAPC 2147
G + ++ + S Q G N NYP RCD
Sbjct: 890 --------GGRLKAEVQTKELYSH---------------AQFGDN---NYPSEARCD--- 920
Query: 2148 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAV 2203
W+I G+GV + F + E DY+
Sbjct: 921 ---------------------------WVIVAEDGYGVELTFRTFEVEEEADCGYDYMEA 953
Query: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
+DG D ++P+LG F G+ LE YS+ + ++++F +D
Sbjct: 954 YDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTD 990
Score = 183 bits (464), Expect = 3e-45
Identities = 174/669 (26%), Positives = 265/669 (39%), Gaps = 132/669 (19%)
Query: 391 QRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKV 450
QRV + + R + + CG L+ +G ++P +P Y +HCVW I+ T +K+
Sbjct: 330 QRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKI 389
Query: 451 IKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQ 506
+ L F +L + YD + V D +L G +P+ +VS +++W+ +
Sbjct: 390 V-LNFTSMDLFKSRLCWYDYVEVRDG--YWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
Query: 507 SDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVI 566
S +I GF A Y+ CG GD + +
Sbjct: 447 SSSNILGKGFFAAYE----ATCG-----------------GD------------MNKDAG 473
Query: 567 TCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLI 626
Q N +PS C + T S G + L
Sbjct: 474 QIQSPNYPDDYRPS--KECVWRITVSEGF--------------------------HVGLT 505
Query: 627 FNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTT 682
F F++E +D+L V+D + ++G F G E P + SS + + ++F SD S
Sbjct: 506 FQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSIN 565
Query: 683 GRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQ 742
GF + E + P +G C+ V T GS C
Sbjct: 566 KAGFAANFF----KEVDECSWPDHG---------------GCEHRCVNTLGSYKCAC--- 603
Query: 743 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFD 802
D ++ CE CGG +T +G I PGWP Y + +C W + A + I + F+
Sbjct: 604 DPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFE 663
Query: 803 RFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSI 858
F+ E N YD +EVR G + + L G + G++ P+ + S N M + F +DN+ S
Sbjct: 664 VFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKR 723
Query: 859 GFLIHYESVTLESDSCLDPGIPVNG---HRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCE 915
GF H+ S + D C NG H FG + C GY L E
Sbjct: 724 GFRAHFFS---DKDECAKD----NGGCQHECVNTFG---SYLCRCRNGYWLH-------E 766
Query: 916 RNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHT 975
H +A C I GT+ SP +PD YP+ CTW I + G V++ F+
Sbjct: 767 NGHDCK------EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE 820
Query: 976 F----HLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSIS 1030
F H E ++D+L + + P+ R GS P A F LRF SD S+
Sbjct: 821 FEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMF---LRFYSDASVQ 877
Query: 1031 YEGFNITFS 1039
+GF S
Sbjct: 878 RKGFQAVHS 886
Score = 182 bits (463), Expect = 4e-45
Identities = 136/466 (29%), Positives = 212/466 (45%), Gaps = 61/466 (13%)
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT----- 1157
A CG + + G + SPN+P +Y + EC+++I G + L ++F++ D+
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
L+V DG S +G F E + S+SN LW++F ++GS GF + +
Sbjct: 522 LEVRDGPTEESALIGHFCGYEKPEDV-KSSSNRLWMKFVSDGSINKAGFAANFFK----E 576
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLY--SCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
++ P++G E +T+ Y +C+PGY L+ D+++ C
Sbjct: 577 VDECSWPDHG---GCEHRCVNTLGSYKCACDPGYE---------LAADKKM-------CE 617
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
CGG I +G I SPG+P Y N +C W + A ISL F VF+ E +D
Sbjct: 618 VACGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYD 676
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
++V G L + GS PE I S N++ ++F SD +SK GF F +
Sbjct: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSD---- 732
Query: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
D NG + + +C GY L C + A
Sbjct: 733 -KDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGH-DCKE---------------AG 775
Query: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLH 1507
C ++ G + SPN+P YP +EC W + + L F F +E +YD L
Sbjct: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835
Query: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
+Y+G DS +P++G + GS+ P+ +SG+S+FL F SDASV GF
Sbjct: 836 MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
Score = 179 bits (454), Expect = 4e-44
Identities = 162/642 (25%), Positives = 265/642 (41%), Gaps = 129/642 (20%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVIS---FATEQNW-DSLE 1858
C G +PG+P Y + +C+W+I VT G I + S F + W D +E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
+ DG AP LG F G +P L ST ++L++ F+S ++ GF Y+ A C
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG- 465
Query: 1919 PALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGT 1978
GD M D G ++ NYP
Sbjct: 466 ----------GD--MNKDA---------------------GQIQSPNYPD---------- 482
Query: 1979 LSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEIQNG 2034
Y + +C WRI++ G+ + F F E + +D+LE+++G
Sbjct: 483 ---------------DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDG 527
Query: 2035 PYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPF 2094
P S +IG F G + P + S+++ + F SD S N+ GF + E+ C P
Sbjct: 528 PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF-FKEVDECSWP--- 583
Query: 2095 QNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQ 2154
+G + + S C PGY L + C+ CG +T
Sbjct: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKM----------------CEVACGGFITKL 627
Query: 2155 NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVWDGPDQN 2210
NGTI SPG+P EYP K+C+W + P + + + F + + E + D++ V G +
Sbjct: 628 NGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPD 687
Query: 2211 SPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLK-KCQPPPAVPQ 2267
+ G F G+ E S +N + ++F SD S GF H F K +C Q
Sbjct: 688 AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF---RAHFFSDKDECAKDNGGCQ 744
Query: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRT 2327
E + G ++ +C GY L E EA C A+++ +
Sbjct: 745 HECVN-----TFGSYL-CRCRNGYWL---------------HENGHDCKEAGC-AHKI-S 781
Query: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGSS 2383
G + SP +P Y + + C+W+I + + + + F+ E+ +D LE++DG
Sbjct: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
Query: 2384 GQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFK 2425
+P+L G+ S S+ ++LR+ +D + +KGF+
Sbjct: 842 SLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQ 882
Score = 154 bits (390), Expect = 1e-36
Identities = 133/509 (26%), Positives = 200/509 (39%), Gaps = 95/509 (18%)
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE--- 257
F E CGG + + I SP++P +Y + +C W I G + L F F++E
Sbjct: 457 FAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
Query: 258 -GYDFLEISG--TEAPSI--WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVK 312
YD+LE+ TE ++ G P V SS N L + F SD + + GF A F
Sbjct: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF--- 573
Query: 313 KAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANV 372
K P G V + G +
Sbjct: 574 ----FKEVDECSWPDHGGCEHRCVNTLG------------------------------SY 599
Query: 373 QFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQY 432
+ +C+ Y L K + C CG + +G ITSP +P +Y
Sbjct: 600 KCACDPGYELAADKKM------------------CEV-ACGGFITKLNGTITSPGWPKEY 640
Query: 433 EDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGS 488
N +CVW + + I L FE FELE YD + V + + GS
Sbjct: 641 PTNKNCVWQVVAPAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGS 697
Query: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGD 548
P++I S SN M + +SD+++ GF+A + +K C K G
Sbjct: 698 ETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECA--------KDNGGC----- 743
Query: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFS-CFFNFTASSGIILSPNYPEEYGN 607
EC F G + C+ N C + C ++ G + SPN+P++Y +
Sbjct: 744 --QHECVNTF---GSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798
Query: 608 NMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQ 663
C W I S G R+ L FN+F++E +D L + D S +LG F G++ P
Sbjct: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDP 858
Query: 664 LASSGHIVRLEFQSDHSTTGRGFNITYTT 692
+SG + L F SD S +GF ++T
Sbjct: 859 TVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 143 bits (361), Expect = 3e-33
Identities = 173/706 (24%), Positives = 262/706 (37%), Gaps = 160/706 (22%)
Query: 4 WRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIII 63
W F+S +LG + AA CGG + G I+SP +P Y C W I
Sbjct: 442 WVEFRSSSNILG------KGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT 495
Query: 64 TGERNRIQLSFHTFALEED----FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILT 119
E + L+F F +E +D L V DG ++ L G++ P + S+ + L
Sbjct: 496 VSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLW 555
Query: 120 LWFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEG 179
+ F +D +++ GF A + C P G H +G + +C PGY L
Sbjct: 556 MKFVSDGSINKAGFAANF-FKEVDECSWPDH--GGCEHRCVNTLGS-YKCACDPGYELAA 611
Query: 180 HAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTIL 239
+ E ACGG + + +I+SP +P EY N +C W ++
Sbjct: 612 DKKM--------------------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVV 651
Query: 240 AEPGDTIALVFTDFQLEEG----YDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFT 295
A I+L F F+LE YDF+E+ +P L G S T
Sbjct: 652 APAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEV-------IT 704
Query: 296 SDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIP 355
S SN+ R F + V K RG + D D C
Sbjct: 705 SQSNNMRVEFKSDNTVSK------RGFRAHFFSD----------------KDECAK---- 738
Query: 356 ENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAW-SDHRPICRARTCGS 414
+NG Q C + + GS C+ W ++ C+ C
Sbjct: 739 DNG------------GCQHECVNTF---GSYLCRCRN-----GYWLHENGHDCKEAGCAH 778
Query: 415 NLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDTLTVG 470
+ G + SPN+P +Y C W I++T +V KL F EFE+E+ YD L +
Sbjct: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV-KLTFNEFEIEQHQECAYDHLEMY 837
Query: 471 DAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGD 530
D +L GS PD V+ GS F Y +
Sbjct: 838 DGPD--SLAPILGRFCGSKKPDPTVAS--------------GSSMFLRFYSD-------- 873
Query: 531 PGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFT 590
A +R G +H EC G R+ Q + +
Sbjct: 874 ----ASVQRKGFQAVHST----EC-------GGRLKAEVQTKELYSH------------- 905
Query: 591 ASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGI 646
A G NYP E C W+I++E G + L F F+VE + +D++ D
Sbjct: 906 AQFG---DNNYPSE----ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYD 958
Query: 647 SDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
S LG F G+ ++ S+G + + F++D + +GF+ YT+
Sbjct: 959 SSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 119 bits (298), Expect = 5e-26
Identities = 94/331 (28%), Positives = 143/331 (43%), Gaps = 39/331 (11%)
Query: 2140 FPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE---- 2195
F +A CG ++ G I SP +PD+Y K+C+W ITV G V + F + E
Sbjct: 457 FAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
Query: 2196 AVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAF 2254
DY+ V DGP + S +G F G E SS+N++ +KF SD S N F NF
Sbjct: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK- 575
Query: 2255 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
++ +C P +G + K C PGY L +
Sbjct: 576 EVDECSWPDHGGCEHRCVN----TLGSY-KCACDPGYELAADKKM--------------- 615
Query: 2315 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK--- 2371
CE C T +G I SPG+P Y ++ C W + Y I++ + F+ E
Sbjct: 616 -CEVAC--GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDV 672
Query: 2372 -QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
++D +EV G S + L G+ T + TS+SN + + + +D+ SK+GF+ + +
Sbjct: 673 CKYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
Query: 2431 PYCSLTHPLKNGGILNRTAGAVGSKVHYFCK 2461
NGG + GS Y C+
Sbjct: 732 DKDECAK--DNGGCQHECVNTFGS---YLCR 757
Score = 71.6 bits (174), Expect = 1e-11
Identities = 41/119 (34%), Positives = 62/119 (52%), Gaps = 8/119 (6%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CG +Q G +PGFP+GYP+Y++C W I +I L+F + L + +D +
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
V DG ++ L R G ++P +VST S L + F + + +GF A YE TCG
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TCG 465
Score = 67.8 bits (164), Expect = 2e-10
Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
Query: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
ACG L G +P +P YP C WR+ V P I L F S ++ S YD++
Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
+ +G +PL+G + G + PE + S+ + L++ FRS +++ GF
Sbjct: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGF 456
Score = 67.4 bits (163), Expect = 2e-10
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 8/112 (7%)
Query: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
ACG TL+ T+ + S+P FP+ Y + + C W I PG+ I L FT L + YD++
Sbjct: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
E+ +AP + G +P P++S+ + L + F S SN KGF A ++
Sbjct: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
Score = 64.7 bits (156), Expect = 2e-09
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 7/112 (6%)
Query: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
+C A CG + G +PGFP+ YP C+W I+V PG + +NFT +
Sbjct: 347 KCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCW 405
Query: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFF 2247
DY+ V DG + +P LG F G+ E S+ +++ ++F S+ GFF
Sbjct: 406 YDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
Score = 60.1 bits (144), Expect = 4e-08
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 6/147 (4%)
Query: 561 VGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPG 620
+G+RV Q + + C +C ++G +P +P Y + +CVW I PG
Sbjct: 328 IGQRVRLSQGDIAQARKLYKCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPG 386
Query: 621 SRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQ 676
+I L F D+ +D++ V+D +LG F G+++P L S+ + +EF+
Sbjct: 387 EKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
Query: 677 SDHSTTGRGFNITY-TTFGQNECHDPG 702
S + G+GF Y T G + D G
Sbjct: 447 SSSNILGKGFFAAYEATCGGDMNKDAG 473
Score = 59.7 bits (143), Expect = 5e-08
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 779 YKDSLHCEWIIEAKPGHSIKITFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQA 834
Y C+W+I A+ G+ +++TF F+ E YD +E DG SS+P +G + G+
Sbjct: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972
Query: 835 PQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
+ + S G+ + + F TD++ + GF Y S +
Sbjct: 973 LEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
Score = 59.3 bits (142), Expect = 7e-08
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 16/201 (7%)
Query: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD----RRVWDKPLPSCIAEC 1278
I +Y G F DT++ + G + GD R+++ P+C
Sbjct: 298 IMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYK--CPAC---- 351
Query: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
G+ T+G +PG+P Y + HC W I PG+ I L+F D + +D ++
Sbjct: 352 -GETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCN- 1393
V DG LL + G +PE + ST + L ++F S I GF + + N
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
Query: 1394 DPGMPQNGTRYGDSREAGDTV 1414
D G Q+ D R + + V
Sbjct: 471 DAGQIQSPNYPDDYRPSKECV 491
Score = 54.7 bits (130), Expect = 2e-06
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 7/118 (5%)
Query: 1098 LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-- 1155
L +C A CG +++ G +P FP+ Y + C+++I G+ I L S LF+
Sbjct: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
Query: 1156 ---DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
D ++V DG + LG F +++ ++ ST + LW+EF ++ + +GF Y
Sbjct: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLV-STDSRLWVEFRSSSNILGKGFFAAY 460
Score = 53.5 bits (127), Expect = 4e-06
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 1994 SYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHDFLEIQNGPYHTSPMIGQFSGTD 2049
+YP+ C W I GYG + F F E +D++E +G ++P +G+F G+
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 2050 LPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2087
+ S +I F +D + N++GF Y + + Q+
Sbjct: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQD 1009
Score = 50.4 bits (119), Expect = 3e-05
Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 208 CGGTLRG---TSSSISSPHF-PSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
CGG L+ T S F + Y + A C W I+AE G + L F F++EE GY
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
Query: 260 DFLEI---SGTEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
D++E + AP + G + S+ + L + F +D +KGF+A++ K
Sbjct: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 48.9 bits (115), Expect = 9e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 15/141 (10%)
Query: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
+CPA E ++G +PG+P Y + C W I V P I + +D F+S +
Sbjct: 347 KCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWY 406
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYC 2433
D +EV DG ++PLL G+ + S ++L++ + + KGF Y A
Sbjct: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEP-LVSTDSRLWVEFRSSSNILGKGFFAAYEATC- 464
Query: 2434 SLTHPLKNGGILNRTAGAVGS 2454
GG +N+ AG + S
Sbjct: 465 --------GGDMNKDAGQIQS 477
Score = 42.0 bits (97), Expect = 0.011
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
CG + G +P +P+ Y + C++ I+V P E +V F F++ L D E
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQA 1733
+ DG +A LL G E L ++T +++ + F + S +GF Y+A
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAYEA 462
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 207 bits (528), Expect = 1e-52
Identities = 179/656 (27%), Positives = 283/656 (43%), Gaps = 132/656 (20%)
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
A CGG+I G+I SP YP Y C W I + L F F+ E A+D
Sbjct: 460 AICGGEIRK-NEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
L+V DG ++ L+ + G PEDI ST N+L ++F SD ++K+GF+ F
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKE-EDE 577
Query: 1392 CNDPGMPQNGTRYGDSREAGDTV-TFQC--DPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C P R G + +T+ ++QC +PGY+L PD +C
Sbjct: 578 CAKPD------RGGCEQRCLNTLGSYQCACEPGYELG-----------------PDRRSC 614
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YD 1504
AACGG LT G I +P +P+ YPP K C W+V + I++ F+ F +E + YD
Sbjct: 615 EAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREA 1564
++ I+ G S S L G + G++ PE I S N++ + F+SD +V GF F E
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
D G + V T +GS + QC +G+ +L + C A
Sbjct: 735 SKDNGGCQHEC-VNT---MGSYMC-QCRNGF-VLHDNKHDCK----------------EA 772
Query: 1625 PCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYF-----QTALNDLA 1679
C + G++ SPN+P Y + + C + I+ + F+ F Q D
Sbjct: 773 ECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832
Query: 1680 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
E+FDG ++ +L L G+ + L +AT N++ +RF + + +GF T
Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPL-VATGNKMFVRFVSDASVQRKGFQ-------ATHS 884
Query: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
T+C G ++ E P L + AQ+ D
Sbjct: 885 TEC------------------GGRLKAESKPRDLY-------------SHAQFGDN---- 909
Query: 1800 VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQ----NWD 1855
YP ++C W ++ GS +++ +F E+ +D
Sbjct: 910 ------------------NYP----GQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYD 947
Query: 1856 SLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
+E+ DG D TA LG F G+ P + S + + +HF +D ++ GFH+ YK++
Sbjct: 948 YVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 206 bits (524), Expect = 3e-52
Identities = 188/681 (27%), Positives = 278/681 (40%), Gaps = 164/681 (24%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CGG ++ G I+SP +P Y C W I E + L+F +F +E +D L
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG + L R G+ P I ST + L + F +D V+ GF A + C
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF-FKEEDECAK 580
Query: 148 PGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGA 207
P +G N + +C PGY L G +C E A
Sbjct: 581 PD---RGGCEQRCLNTLGSYQCACEPGYEL-GPDRRSC-------------------EAA 617
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263
CGG L + +I++P +P EY N +C W ++A I++ F F+LE YD++E
Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677
Query: 264 I-SGTEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319
I SG + S G +P + S N +R+ F SD+ +KGF A F K K
Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKD 737
Query: 320 RGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDN 379
G G V + G S MC C +
Sbjct: 738 NG--------GCQHECVNTMG-----SYMC-------------------------QCRNG 759
Query: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+VL D++ C+ C + PSG+ITSPN+P +Y C
Sbjct: 760 FVLH------------------DNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECT 801
Query: 440 WVITTTDPDKVIKLAFEEFELER----GYDTLTVGDAGKVGDTRS--VLYVLTGSSVPDL 493
W I+ T P IKLAF EFE+E+ YD L V D G+T +L L G+ +PD
Sbjct: 802 WEISAT-PGHRIKLAFSEFEIEQHQECAYDHLEVFD----GETEKSPILGRLCGNKIPDP 856
Query: 494 IVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFE 553
+V+ N+M++ SD S+ GF+A T + E
Sbjct: 857 LVATGNKMFVRFVSDASVQRKGFQA------------------------------THSTE 886
Query: 554 CPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVW 613
C + + +KP ++S A G NYP + ++C W
Sbjct: 887 CGGRLK---------------AESKPRDLYS-----HAQFG---DNNYPGQ----VDCEW 919
Query: 614 LIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGH 669
L++SE GSR+ L F F+VE + +D++ + D S LG F G+ P ++ S G
Sbjct: 920 LLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGD 979
Query: 670 IVRLEFQSDHSTTGRGFNITY 690
V + F +D + +GF+I Y
Sbjct: 980 SVLIHFHTDDTINKKGFHIRY 1000
Score = 199 bits (507), Expect = 3e-50
Identities = 139/454 (30%), Positives = 215/454 (47%), Gaps = 56/454 (12%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G + G I SP YP+ Y C+WKI V+E + + SF E++ +D LE
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
+ DG +P +G F G P + STSN L++ F SD +V AGF + E
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF----FKEEDE 577
Query: 1919 PALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCG 1976
A P ++ +N + S+QC EPGY L G RR C A CG
Sbjct: 578 CAKPDRGGC--EQRCLNTLGSYQCACEPGYEL----------GPDRR------SCEAACG 619
Query: 1977 GTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEIQ 2032
G L+ L G I +PG+P YP N +C W++ P Y ++F F E N +D++EI
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPP 2092
+G S + G+F G ++P + S + I F SD++ +++GFK A+ + C
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFK-AHFFSDKDECSK-- 736
Query: 2093 PFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVT 2152
NG + + S +C G++L + +H +A C +
Sbjct: 737 --DNGGCQHECVNTMGSYMCQCRNGFVLHDN-----KHDCK----------EAECEQKIH 779
Query: 2153 SQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDYIAVWDGPD 2208
S +G I SP +PD+YP K+C W I+ PGH + + F+ + E D++ V+DG
Sbjct: 780 SPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGET 839
Query: 2209 QNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2242
+ SP LG GN + ++ N++ ++F SD S
Sbjct: 840 EKSPILGRLCGNKIPDPLVATGNKMFVRFVSDAS 873
Score = 198 bits (503), Expect = 9e-50
Identities = 143/468 (30%), Positives = 216/468 (46%), Gaps = 65/468 (13%)
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT----- 1157
A CG ++ NEG + SPN+P +Y EC++KI + L +SF++ D
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
L+V DG +S +G F + I STSN LW++F ++G+ GF + + +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDI-RSTSNTLWMKFVSDGTVNKAGFAANFFK-EEDE 577
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLY--SCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
C P R E +T+ Y +C PGY L DRR SC
Sbjct: 578 CAKPD------RGGCEQRCLNTLGSYQCACEPGYE---------LGPDRR-------SCE 615
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
A CGG + +G I +PG+P Y N +C W + A IS+ F F+ E +D
Sbjct: 616 AACGGLL-TKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
+++W G L ++ G+ +PE I S FN++ ++F SD +SK GF F +
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 1392 CNDPGMPQNGTRYGDSREAGDTV-TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-I 1449
D G G E +T+ ++ C Q N F + C
Sbjct: 735 SKDNG--------GCQHECVNTMGSYMC---------------QCRNGFVLHDNKHDCKE 771
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDF 1505
A C + P+G+I SPN+P YP KEC W + P I L F F +E +YD
Sbjct: 772 AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831
Query: 1506 LHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
L +++GE SP++G G++ P+ + ++GN +F+ F SDASV GF
Sbjct: 832 LEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGF 879
Score = 197 bits (501), Expect = 2e-49
Identities = 137/461 (29%), Positives = 209/461 (45%), Gaps = 55/461 (11%)
Query: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDTL 467
CG +R G I SPNYP Y CVW IT ++ V L F+ FE+ER YD L
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHV-GLTFQSFEIERHDNCAYDYL 520
Query: 468 TVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGG 527
V D + ++ G P+ I S SN +W+ SD ++ GF A + + E+
Sbjct: 521 EVRDG--TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFK-EEDE 577
Query: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFF 587
C P +R +G C+ + ++ SC +C
Sbjct: 578 CAKPDRGGCEQR-----------------CLNTLGSYQCACEPGYELGPDRRSCEAACGG 620
Query: 588 NFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLAVKD 643
T +G I +P +P+EY N NCVW +++ RI + F F++E ++D++ +
Sbjct: 621 LLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWS 680
Query: 644 DGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGI 703
S+ + G F G EVP + S + +R+EF+SD++ + +GF + + ++EC
Sbjct: 681 GLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKDEC----- 734
Query: 704 PINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHL 763
S + C V T GS C ++G V+ + EA C +
Sbjct: 735 --------------SKDNGGCQHECVNTMGSYMCQC--RNGFVLHDNKHDCKEAECEQKI 778
Query: 764 TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YDTLEVRDGP 819
+ SG+I P WP Y C W I A PGH IK+ F F+ E + YD LEV DG
Sbjct: 779 HSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGE 838
Query: 820 ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGF 860
SP++G G + P L++TGN M++ F +D S GF
Sbjct: 839 TEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGF 879
Score = 180 bits (457), Expect = 2e-44
Identities = 137/489 (28%), Positives = 215/489 (43%), Gaps = 60/489 (12%)
Query: 566 ITCQQNNQWSGNKPSCVFS--CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRI 623
I + ++ W G + V+ C + G I SPNYP++Y CVW I +
Sbjct: 441 IEFRSSSNWVGKGFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHV 500
Query: 624 HLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDH 679
L F F++E +D+L V+D + ++G F G + P + S+ + + ++F SD
Sbjct: 501 GLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDG 560
Query: 680 STTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITC 739
+ GF + ++EC P R G C+ + T GS C
Sbjct: 561 TVNKAGFAANFFK-EEDECAKPD------RGG------------CEQRCLNTLGSYQCAC 601
Query: 740 ILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKI 799
+ CEA CGG LT +G I PGWP Y + +C W + A + I +
Sbjct: 602 ---EPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISV 658
Query: 800 TFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSR 855
F+ F+ E N YD +E+ G +S S L G++ G + P+ + S N M + F +DN+
Sbjct: 659 KFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTV 718
Query: 856 SSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCE 915
S GF H+ S + D C NG + C G+ L D++
Sbjct: 719 SKKGFKAHFFS---DKDECSKD----NGGCQHECVNTMGSYMCQCRNGFVLHDNK----- 766
Query: 916 RNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHT 975
H +A C I SG + SP +PD YP+ CTW I + G +++ F
Sbjct: 767 --HDCK------EAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSE 818
Query: 976 F----HLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSIS 1030
F H E ++D+L + + + P+ RL G+ +P + A GN +RF+SD S+
Sbjct: 819 FEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVA--TGN-KMFVRFVSDASVQ 875
Query: 1031 YEGFNITFS 1039
+GF T S
Sbjct: 876 RKGFQATHS 884
Score = 180 bits (456), Expect = 3e-44
Identities = 137/472 (29%), Positives = 213/472 (45%), Gaps = 62/472 (13%)
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
A CGG + G I SP +P Y +C W+I++ Y + F +F E + +D+
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
LE+++G SP+IG+F G D P + ST++ + F SD + N+ GF + E C
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEE-DEC 578
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
P + G ++G S C PGY L G +R C+A CG
Sbjct: 579 AKPD--RGGCEQRCLNTLG-SYQCACEPGYEL----------GPDRR------SCEAACG 619
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVW 2204
+T NGTI +PG+P EYP K+C+W + P + + + F + E DY+ +W
Sbjct: 620 GLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIW 679
Query: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLK-KCQP 2261
G S G F G E S N + ++F SD S GF H F K +C
Sbjct: 680 SGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGF---KAHFFSDKDECSK 736
Query: 2262 PPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCP 2321
Q E + +G ++ QC G+ L CK EA+C
Sbjct: 737 DNGGCQHECVNT-----MGSYM-CQCRNGFVLHDNKH-DCK--------------EAEC- 774
Query: 2322 ANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALE 2377
+ SG+I SP +P Y + + C+W I P + I + F+ E+ +D LE
Sbjct: 775 -EQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833
Query: 2378 VFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
VFDG + +SP+L L GN + N++++R+ +D + +KGF+ ++
Sbjct: 834 VFDGETEKSPILGRLCGNKIPDP-LVATGNKMFVRFVSDASVQRKGFQATHS 884
Score = 172 bits (437), Expect = 4e-42
Identities = 167/691 (24%), Positives = 264/691 (38%), Gaps = 174/691 (25%)
Query: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GYD 260
E CGG +R I SP++P +Y +C W I + L F F++E YD
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 261 FLEI-SGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
+LE+ GT S + G + P + S+ N L + F SD + GF A F
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF------- 571
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSC 376
K P + G + + + G + Q +C
Sbjct: 572 FKEEDECAKPDRGGCEQRCLNTLG------------------------------SYQCAC 601
Query: 377 EDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNA 436
E Y L R C A CG L +G IT+P +P +Y N
Sbjct: 602 EPGYEL------------------GPDRRSCEA-ACGGLLTKLNGTITTPGWPKEYPPNK 642
Query: 437 HCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPD 492
+CVW + + I + FE FELE YD + + + + G+ VP+
Sbjct: 643 NCVWQVVAPTQYR-ISVKFEFFELEGNEVCKYDYVEIWSG--LSSESKLHGKFCGAEVPE 699
Query: 493 LIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTF 552
+I S N M + +SD+++ GFKA + +K C K G
Sbjct: 700 VITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKDECS--------KDNGGC-------QH 743
Query: 553 ECPAAFELVGERVITCQQNNQWSGNKPSCVFS-CFFNFTASSGIILSPNYPEEYGNNMNC 611
EC +G + C+ NK C + C + SG+I SPN+P++Y + C
Sbjct: 744 EC---VNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKEC 800
Query: 612 VWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASS 667
W I + PG RI L F++F++E +D L V D +LG GN++P L ++
Sbjct: 801 TWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVAT 860
Query: 668 GHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDG 727
G + RF+ +SV G
Sbjct: 861 ---------------------------------------GNKMFVRFVSDASVQ---RKG 878
Query: 728 FVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGY-------YK 780
F T +E CGG L A S P + Y
Sbjct: 879 FQATHSTE-----------------------CGGRLKAESK---PRDLYSHAQFGDNNYP 912
Query: 781 DSLHCEWIIEAKPGHSIKITFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQAPQ 836
+ CEW++ ++ G ++++F F+ E YD +E+ DG S++ +G + G+ P+
Sbjct: 913 GQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPE 972
Query: 837 FLISTGNFMYLLFTTDNSRSSIGFLIHYESV 867
+ S G+ + + F TD++ + GF I Y+S+
Sbjct: 973 EIYSIGDSVLIHFHTDDTINKKGFHIRYKSI 1003
Score = 169 bits (428), Expect = 5e-41
Identities = 165/637 (25%), Positives = 255/637 (40%), Gaps = 128/637 (20%)
Query: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALND-----L 1678
A CGG+ +EG + SPNYP +Y + C++ ITV + + V F F+ +D
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDY 519
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTS 1738
E+ DGT + L+ G E + +TSN + ++F + + GF +
Sbjct: 520 LEVRDGTSENSPLIGRFCGYDKPEDIR-STSNTLWMKFVSDGTVNKAGFAANFFK----E 574
Query: 1739 DTQCSSVP----EPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWND 1794
+ +C+ E R +GS A C PGY L
Sbjct: 575 EDECAKPDRGGCEQRCLNTLGSYQCA-------CEPGYELGPDRR--------------- 612
Query: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN- 1853
SC C G T+ GTI +PG+P+ Y N NC+W+++ I ++ F E N
Sbjct: 613 ---SCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNE 669
Query: 1854 ---WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1910
+D +EI G + G F G VP ++ S N + + F+SD +V+ GF +
Sbjct: 670 VCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHF-- 727
Query: 1911 VGLAACQEPALPSNSIKIGDRYMVNDVLSF--QCEPGYTLQGRSHISCMPGTVRRWNYPS 1968
+ E + + + VN + S+ QC G+ L H C
Sbjct: 728 --FSDKDECSKDNGGCQ---HECVNTMGSYMCQCRNGFVLHDNKH-DCKE---------- 771
Query: 1969 PLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN--- 2025
A C + + G+I SP +P YP+ +CTW IS G+ + F F E +
Sbjct: 772 ----AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQEC 827
Query: 2026 -HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYE 2084
+D LE+ +G SP++G+ G +P L++T ++ + F SD S R+GF QA
Sbjct: 828 AYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGF----QATH 883
Query: 2085 LQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2144
C G + E P L H Q G N NYP
Sbjct: 884 STEC------------------GGRLKAESKP-RDLYSH----AQFGDN---NYP---GQ 914
Query: 2145 APCGYNVTSQNGTIYSPGFPD-EYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
C + + S+ G+ F E DC + DY+ +
Sbjct: 915 VDCEWLLVSERGSRLELSFQTFEVEEEADCGY-----------------------DYVEL 951
Query: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
+DG D + LG F G+ E YS + VL+ FH+D
Sbjct: 952 FDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTD 988
Score = 156 bits (395), Expect = 3e-37
Identities = 134/502 (26%), Positives = 220/502 (43%), Gaps = 65/502 (12%)
Query: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SHD 983
+A+CGG I+ G + SP +PD Y C W I VS V + F +F +E ++D
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 984 YLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
YL + + S + P + R G P I++ + T ++F+SD +++ GF F + +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRST---SNTLWMKFVSDGTVNKAGFAANFFKEE 575
Query: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
E C P +R G S +C GY L G RR C
Sbjct: 576 DE-CAKPDRGGCEQRCLNTLG---SYQCACEPGYEL---------GPDRR-------SCE 615
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG------D 1156
A CG + GT+ +P +P Y N C++++ I ++ F+L EG D
Sbjct: 616 AACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFEL-EGNEVCKYD 674
Query: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLV 1216
++++ G S S+ G F E+ +I S N++ +EF ++ + + +GF+ + S D
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVI-TSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKD 732
Query: 1217 KCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
+C + G + + C G+ +H N C A
Sbjct: 733 ECSKDNGGCQHECVNTMGSY-----MCQCRNGFVLH-DNKHDCKE--------------A 772
Query: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHDI 1332
EC +IH+ SG I SP +P Y + CTW I A PG I L F F+ E A+D
Sbjct: 773 ECEQKIHSP-SGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831
Query: 1333 LKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATC 1392
L+V+DG + +L G+ +P+ + +T N + ++F SD + + GF ST
Sbjct: 832 LEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRL 891
Query: 1393 NDPGMPQ---NGTRYGDSREAG 1411
P+ + ++GD+ G
Sbjct: 892 KAESKPRDLYSHAQFGDNNYPG 913
Score = 125 bits (313), Expect = 1e-27
Identities = 111/415 (26%), Positives = 178/415 (42%), Gaps = 58/415 (13%)
Query: 2144 DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVND 2199
+A CG + G I SP +PD+Y +K+C+W ITV + V + F + E D
Sbjct: 459 EAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYD 518
Query: 2200 YIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKK 2258
Y+ V DG +NSP +G F G E S++N + +KF SD + N F NF + +
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDEC 578
Query: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
+P + L ++ C PGY L G D +CEA
Sbjct: 579 AKPDRGGCEQRCLNTLGSYQCA------CEPGYEL-GPD---------------RRSCEA 616
Query: 2319 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----QFD 2374
C + T +G I +PG+P Y ++ C W + Y I++ + F+ E ++D
Sbjct: 617 AC--GGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYD 674
Query: 2375 ALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA--PY 2432
+E++ G S +S L G + TS+ N + + + +D+ SKKGFK + +
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEV-ITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDE 733
Query: 2433 CSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSN------ATCRR---NPLGMY- 2482
CS NGG + +GS Y C+ V H N A C + +P G+
Sbjct: 734 CS----KDNGGCQHECVNTMGS---YMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLIT 786
Query: 2483 --QWDSLTPLCQAVSCGIPESPGNG---SFTGNEFTLDSKVVYECHEGFKLESSQ 2532
W P + + I +PG+ +F+ E + Y+ E F E+ +
Sbjct: 787 SPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEK 841
Score = 79.0 bits (193), Expect = 8e-14
Identities = 74/292 (25%), Positives = 121/292 (41%), Gaps = 69/292 (23%)
Query: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----F 83
K C + P+G I SP +P YP+ CTW I +RI+L+F F +E+ +
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 84 DILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSH 143
D L V+DG+ ++ + RL G ++P +V+TG+ + + F +D +V +GF+A + S
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH----ST 885
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGN-GASWDFPAPFC 202
CG R K R L HA PG W +
Sbjct: 886 ECGG------------RLKAESKPR-------DLYSHAQFGDNNYPGQVDCEWLLVSE-- 924
Query: 203 RAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFL 262
RG+ +S F E E ADC GYD++
Sbjct: 925 ----------RGSRLELSFQTF--EVEEEADC-----------------------GYDYV 949
Query: 263 EI-SGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
E+ G ++ ++ L G P + S + + +HF +D +KGF+ +++
Sbjct: 950 ELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
Score = 77.0 bits (188), Expect = 3e-13
Identities = 44/131 (33%), Positives = 70/131 (53%), Gaps = 5/131 (3%)
Query: 741 LQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKIT 800
L G++ + + RC A CG L S+G + PG+P Y HC W + PG I +
Sbjct: 332 LSKGDIAQARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLN 390
Query: 801 F---DRFQTEVN-YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRS 856
F D +++ + YD +EVRDG SPL+G + G + P+ L ST + M++ F + ++
Sbjct: 391 FTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWV 450
Query: 857 SIGFLIHYESV 867
GF YE++
Sbjct: 451 GKGFAAVYEAI 461
Score = 75.1 bits (183), Expect = 1e-12
Identities = 45/126 (35%), Positives = 66/126 (52%), Gaps = 10/126 (7%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CG +Q NG + SPGFP+GYP+Y +C W + +I L+F T L + +D +
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG ++ L R G +LP + ST S + + F + +GF A+YE + CG
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI----CG- 463
Query: 148 PGEILK 153
GEI K
Sbjct: 464 -GEIRK 468
Score = 75.1 bits (183), Expect = 1e-12
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNF----STEANHDFLE 2030
CG TL G + SPGFP YP+ C WR+S+ G + F S+ +D++E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQA 2082
+++G + SP++G+F G LP L ST I F S + +GF Y+A
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 72.4 bits (176), Expect = 8e-12
Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 5/102 (4%)
Query: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
RC A CG + NG + SPGFP+ YP CIW ++V PG + +NFT + +
Sbjct: 345 RCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCW 403
Query: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS 2239
DYI V DG + SP LG F G+ E S+ +++ ++F S
Sbjct: 404 YDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRS 445
Score = 68.9 bits (167), Expect = 8e-11
Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 4/112 (3%)
Query: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
ACG L G + SP +P YP C WRV V P I L F + ++ S YD++
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
+ +G SPL+G + G + PE + S+ + +++ FRS ++ GFA ++
Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYE 459
Score = 66.2 bits (160), Expect = 5e-10
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C + G + SPG+P Y + +CIW++ VT G I + + ++ +D +E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
+ DG +P LG F G +P +L ST +++++ F+S + GF Y+ +
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 63.2 bits (152), Expect = 5e-09
Identities = 35/124 (28%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 404 RPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG 463
R + R CG L+ +G ++SP +P Y HC+W ++ T +K++ L F +L +
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIV-LNFTTMDLYKS 399
Query: 464 ----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAV 519
YD + V D +L G +P+++ S ++MW+ +S + GF AV
Sbjct: 400 SLCWYDYIEVRDG--YWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAV 457
Query: 520 YQEI 523
Y+ I
Sbjct: 458 YEAI 461
Score = 62.4 bits (150), Expect = 8e-09
Identities = 40/131 (30%), Positives = 65/131 (49%), Gaps = 7/131 (5%)
Query: 1085 TCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
T L G + L RC A CG +++ + G L SP FP+ Y + CI+++ G+ I
Sbjct: 330 TRLSKGDIAQARKLYRCPA-CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIV 388
Query: 1145 LRTRSFQLFEG-----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNG 1199
L + L++ D ++V DG S LG F + L +L ST + +W+EF ++
Sbjct: 389 LNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFC-GDKLPEVLTSTDSRMWIEFRSSS 447
Query: 1200 SDTDQGFQLTY 1210
+ +GF Y
Sbjct: 448 NWVGKGFAAVY 458
Score = 61.2 bits (147), Expect = 2e-08
Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 4/111 (3%)
Query: 584 SCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFL 639
+C S+G + SP +P Y + +C+W + PG +I L F D+ +D++
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407
Query: 640 AVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
V+D +LG F G+++P L S+ + +EF+S + G+GF Y
Sbjct: 408 EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Score = 56.2 bits (134), Expect = 6e-07
Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 1994 SYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHDFLEIQNGPYHTSPMIGQFSGTD 2049
+YP +DC W + G + F F E +D++E+ +G T+ +G+F G+
Sbjct: 910 NYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG 969
Query: 2050 LPAALLSTTHETLIHFYSDHSQNRQGFKLAYQA 2082
P + S LIHF++D + N++GF + Y++
Sbjct: 970 PPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKS 1002
Score = 55.8 bits (133), Expect = 7e-07
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 26 AAKGQNCGGLVQG---PNGTIESPGF-PHGYPNYANCTWIIITGERNRIQLSFHTFALEE 81
A CGG ++ P F + YP +C W++++ +R++LSF TF +EE
Sbjct: 881 ATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEE 940
Query: 82 D----FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137
+ +D + ++DG R G P I S G + + F TD ++ +GF Y
Sbjct: 941 EADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000
Query: 138 E 138
+
Sbjct: 1001 K 1001
Score = 55.5 bits (132), Expect = 1e-06
Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 9/114 (7%)
Query: 1272 PSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA-- 1329
P+C G+ ++G + SPG+P Y + HC W + PG+ I L+F D +
Sbjct: 347 PAC-----GETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL 401
Query: 1330 --HDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFS 1381
+D ++V DG LL + G LPE + ST + + ++F S GF+
Sbjct: 402 CWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFA 455
Score = 50.1 bits (118), Expect = 4e-05
Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%)
Query: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----F 2373
+CPA E S+G + SPG+P Y + C W + V P I + T K +
Sbjct: 345 RCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWY 404
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
D +EV DG +SPLL G+ + TS +++++ + + KGF Y A
Sbjct: 405 DYIEVRDGYWRKSPLLGRFCGDKLPEV-LTSTDSRMWIEFRSSSNWVGKGFAAVYEA 460
Score = 49.3 bits (116), Expect = 7e-05
Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 7/85 (8%)
Query: 931 CGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESS----HDYLL 986
CG +Q +G + SPGFP+ YP+ +C W + V+ G+ + + F T L S +DY+
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 987 ITEDGSF--SEPVARLTGSVLPHTI 1009
+ DG + S + R G LP +
Sbjct: 409 V-RDGYWRKSPLLGRFCGDKLPEVL 432
Score = 43.5 bits (101), Expect = 0.004
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
CG S G + SP +P+ Y + C++ ++V P E +V F ++++L D E
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
+ DG ++ LL G E L +T +++ + F + S +GF VY+A+
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVL-TSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 41.6 bits (96), Expect = 0.014
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 6/105 (5%)
Query: 2341 NYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGSSGQSPLLVVLSGNH 2396
NY C W + E + + TF+ E++ +D +E+FDG + L G+
Sbjct: 910 NYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSG 969
Query: 2397 TEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY-AAPYCSLTHPLK 2440
+ + S + + + + TD +KKGF IRY + Y TH K
Sbjct: 970 PPEEIY-SIGDSVLIHFHTDDTINKKGFHIRYKSIRYPDTTHTKK 1013
Score = 35.4 bits (80), Expect = 1.0
Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 12/117 (10%)
Query: 931 CGGYIQGKSGTVLSPGFPDF----YPNSLNCTWTIEVSHGKGVQMIFHTFHLES----SH 982
CGG ++ +S F YP ++C W + G +++ F TF +E +
Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946
Query: 983 DYLLITED-GSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
DY+ + + S + + R GS P I + G+ + + F +D +I+ +GF+I +
Sbjct: 947 DYVELFDGLDSTAVGLGRFCGSGPPEEIYS--IGD-SVLIHFHTDDTINKKGFHIRY 1000
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo
sapiens]
Length = 809
Score = 196 bits (497), Expect = 5e-49
Identities = 138/420 (32%), Positives = 199/420 (47%), Gaps = 19/420 (4%)
Query: 1215 LVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
L+ C P P +G + H T + C+ GY + G TL CL+G R W+ PSC
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFH-CDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 1275 IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILK 1334
+A CGG IH AT GRI+SP NL C W+IEA G+ + LHF + +D L
Sbjct: 232 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 291
Query: 1335 VWDGPVDSDILLKEWSGSALPE-DIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCN 1393
V G ++ + +PE + S SL ++ S+ + S++F C
Sbjct: 292 VRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCF 351
Query: 1394 DPGMPQ-NGTRYGDSREAGDTVTFQCDPGYQLQGQA---KITCVQLNNRFFWQPDPPTCI 1449
P + N T G TF C PGY L+ I CV W P C
Sbjct: 352 APFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEP-HWNDTEPACK 410
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIY 1509
A CGG L+ PAGV+LSP++PQ Y PG++C W V V + I L + N+ D L ++
Sbjct: 411 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLF 469
Query: 1510 EGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRS---DASVGL-SGFAIEFKEKPR-EA 1564
+G+ ++ ++ +G Q R+ SSG L L F++ + GL GF + FKE PR +
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 1565 CFDPGNIMNGTRVGT--DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
C + G R + D G+ +TYQC+ GY++L +TC SW P+C
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC----QWDLSWSAAPPAC 585
Score = 192 bits (489), Expect = 4e-48
Identities = 134/455 (29%), Positives = 211/455 (46%), Gaps = 32/455 (7%)
Query: 1385 STSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPD 1444
S + +C P P +G G T TF CD GYQLQG+ + C+ R W +
Sbjct: 169 SPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN-GTRPSWNGE 227
Query: 1445 PPTCIAACGGNL-TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSY 1503
P+C+A+CGG + G I+SP P C W ++ + L F+ +++
Sbjct: 228 TPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN 287
Query: 1504 DFLHIYEGEDSNSPLIGSYQGSQAPER-IESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1562
D L + G SP+I PER + S SL++ S+ ++ F+
Sbjct: 288 DRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEE 347
Query: 1563 EACFDP----GNIMNGTRVGTDFKLGSTITYQCDSGYKILDP---SSITCVIGADGKPSW 1615
+ CF P GN+ T +++ G+ T+ C GY + P ++I CV + P W
Sbjct: 348 DRCFAPFLAHGNV---TTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE--PHW 402
Query: 1616 DQVLPSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTAL 1675
+ P+C A CGG+ + GVVLSP++P +Y+ GQ C++ + V +E + Q
Sbjct: 403 NDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE 462
Query: 1676 NDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSG----ASARGFHFVY 1731
D+ LFDG AR+L+ L G L L++ + L+F A G +GF +
Sbjct: 463 GDMLTLFDGDGPSARVLAQLRGPQPRRRL-LSSGPDLTLQFQAPPGPPNPGLGQGFVLHF 521
Query: 1732 QAVPRTSDTQCSSVPEPRYGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNAL 1789
+ VPR +DT C +P P +G R S + G+++ ++C PGY L GS L CQ
Sbjct: 522 KEVPR-NDT-CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWD---- 575
Query: 1790 AQWNDTIPSC--VVPCS--GNFTQRRGTILSPGYP 1820
W+ P+C ++ C+ G T G+P
Sbjct: 576 LSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 610
Score = 169 bits (429), Expect = 3e-41
Identities = 160/609 (26%), Positives = 249/609 (40%), Gaps = 95/609 (15%)
Query: 1913 LAACQEPALPSNS-IKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
L +C P P++ + + D + +F C+ GY LQG + C+ GT WN +P C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHP-GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 1972 IATCGGTL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFL 2029
+A+CGGT+ +TLG ++ SP G+ NL C W I G H+ F S + ++D L
Sbjct: 232 MASCGGTIHNATLGRIV-SPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 2030 EIQNGPYHTSPMIGQFSGTDLPA-ALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
+++G SP+I D+P L+S + S+ N L ++A+E C
Sbjct: 291 MVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC 350
Query: 2089 PDPPPFQNGYMINSD--YSVGQSVSFECYPGYILI--GHP-VLTCQHGINRNWNYPFPRC 2143
P +G + +D Y G +F C PGY L G P + C +WN P C
Sbjct: 351 -FAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPAC 409
Query: 2144 DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----D 2199
A CG ++ G + SP +P Y +DC+W + V + LLQ E +N D
Sbjct: 410 KAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRI-----LLQVEILNVREGD 464
Query: 2200 YIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS-----DFSNGGFFVLNFHAF 2254
+ ++DG ++ L G SS + L+F + + G FVL+F
Sbjct: 465 MLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFK-- 522
Query: 2255 QLKKCQPPPAVPQAEM---LTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEG 2311
++ + P +P E D G + YQC PGY L+G+DILTC+ L +
Sbjct: 523 EVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQW--DLSWSA 580
Query: 2312 SLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK 2371
+ P C+ I++ PG N + S+
Sbjct: 581 APPACQK--------------IMTCADPGEIANGHRTA-------------------SDA 607
Query: 2372 QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAP 2431
F GS Q L ++ + +S D T K ++ P
Sbjct: 608 GFPV-----GSHVQYRCL----------PGYSLEGAAMLTCYSRDTGTPKWSDRV----P 648
Query: 2432 YCSLTH-PLKNGGI-------LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQ 2483
C+L + P N G+ L + G + +FC G+ ++G TC P Q
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQ 706
Query: 2484 WDSLTPLCQ 2492
W S PLC+
Sbjct: 707 WTSQPPLCK 715
Score = 168 bits (425), Expect = 1e-40
Identities = 167/654 (25%), Positives = 258/654 (39%), Gaps = 94/654 (14%)
Query: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
PAS P +G G + I T T + +S +L+ SC P
Sbjct: 137 PASPGPPLGPEGGEEETTTTIITTT------TVTTTVTSPAYLL----------SCGFPP 180
Query: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ--WNHALPSCDALCGGYIQ 936
P +G D T TF CD GY L +E L+C + WN PSC A CGG I
Sbjct: 181 RPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIH 240
Query: 937 GKS-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSE 995
+ G ++SP +L C W IE + G+ + + F L+ +D L++ GS
Sbjct: 241 NATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLS 300
Query: 996 PVARLTGSVLPHTIKAGLFGNFTA-QLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAF 1054
PV + S + + GL + + + +S+ + ++ F ++ + C P +
Sbjct: 301 PV--IYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHG 358
Query: 1055 S-RRIGFHFGVGDSLTFSCFLGYRLEGA---TKLTCLGGGRRVWSAPLPRCVAECGASVK 1110
+ + G TFSC GY LE + C+ W+ P C A CG +
Sbjct: 359 NVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELS 418
Query: 1111 GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRP 1170
G +LSP++P +Y +C++ + + K I L+ + EGD L ++DG S+R
Sbjct: 419 EPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARV 478
Query: 1171 LGTFTKNELLGLILNSTSNHLWLEFNTNGSDTD----QGFQLTYTSFDL-VKCEDPGIPN 1225
L + +L+S + L L+F + QGF L + C + P
Sbjct: 479 LAQLRGPQPRRRLLSSGPD-LTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPE 537
Query: 1226 YGYRIRDEGH-FTDTVVLYSCNPGYAMHGSNTLTC---LSGDRRVWDKPLPSC--IAECG 1279
+G+R G TV+ Y C PGY + GS+ LTC LS W P+C I C
Sbjct: 538 WGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLS-----WSAAPPACQKIMTC- 591
Query: 1280 GQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP 1339
ADPG+ + H D P
Sbjct: 592 -------------------------------ADPGEIANGHRTASDAGF----------P 610
Query: 1340 VDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQ 1399
V S + + G +L ++ + D K + C +PG+P+
Sbjct: 611 VGSHVQYRCLPGYSLEG------AAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 1400 NG--TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
NG T Y +AG+++ F C G++L G+ ITCV + W PP C A
Sbjct: 665 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVP-GHPSQWTSQPPLCKVA 717
Score = 164 bits (415), Expect = 1e-39
Identities = 123/438 (28%), Positives = 196/438 (44%), Gaps = 20/438 (4%)
Query: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ--WSGNKPSCVFSC 585
CG P PA+G + + G T TF C + ++L GE + C + W+G PSC+ SC
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASC 235
Query: 586 FFNF-TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDD 644
A+ G I+SP G N+ C W+I + G R+HL F ++ D L V+
Sbjct: 236 GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSG 295
Query: 645 GISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGI 703
G V+ ++VP + L S + +E S+ ++ + F ++ C P +
Sbjct: 296 GSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFL 355
Query: 704 PINGRRFGD-RFLLGSSVSFHCDDGF-VKTQGSESITCILQDGNVVWSSTVPRCEAPCGG 761
D + G+ +F C G+ ++ G + + W+ T P C+A CGG
Sbjct: 356 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGG 415
Query: 762 HLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPAS 821
L+ +GV+L P WP Y C W + + I + + D L + DG
Sbjct: 416 ELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-DMLTLFDGDGP 474
Query: 822 SSPLIGEYHGTQAPQFLISTGNFMYLLFTT----DNSRSSIGFLIHYESVTLESDSCLDP 877
S+ ++ + G Q + L+S+G + L F N GF++H++ V +D+C +
Sbjct: 475 SARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP-RNDTCPEL 533
Query: 878 GIPVNGHRHG--GDFGIRSTV-TFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL--CG 932
P G R GD IR TV T+ C+PGY L + L C+ + W+ A P+C + C
Sbjct: 534 PPPEWGWRTASHGDL-IRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCA 592
Query: 933 --GYIQGKSGTVLSPGFP 948
G I T GFP
Sbjct: 593 DPGEIANGHRTASDAGFP 610
Score = 162 bits (409), Expect = 7e-39
Identities = 145/600 (24%), Positives = 225/600 (37%), Gaps = 84/600 (14%)
Query: 1742 CSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVV 1801
C P P +G ++ G F C+ GY LQG L C + WN PSC+
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLN--GTRPSWNGETPSCMA 233
Query: 1802 PCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
C G G I+SP G NL C W I EG + + + +++ D L +
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 1861 DGGDVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEP 1919
GG +P + VP L S + LY+ S+ L ++ C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 1920 ALPSNSIKIGD-RYMVNDVLSFQCEPGYTLQGR---SHISCMPGTVRRWNYPSPLCIATC 1975
L ++ D Y + +F C PGY L+ + I C+ T WN P C A C
Sbjct: 354 FLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMC 413
Query: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQ-------FLNFSTEANHDF 2028
GG LS GV+LSP +P SY DC W G H+Q + D
Sbjct: 414 GGELSEPAGVVLSPDWPQSYSPGQDCVW--------GVHVQEEKRILLQVEILNVREGDM 465
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNR----QGFKLAYQAYE 2084
L + +G ++ ++ Q G LLS+ + + F + QGF L ++
Sbjct: 466 LTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVP 525
Query: 2085 LQN-CPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFP 2141
+ CP+ PP + G+ S D G ++++C PGY L+G +LTCQ + +W+ P
Sbjct: 526 RNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDL--SWSAAPP 583
Query: 2142 RCD--APCGYNVTSQNG--TIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV 2197
C C NG T GFP + C+ PG+ +
Sbjct: 584 ACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCL------PGYSL------------ 625
Query: 2198 NDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLK 2257
+ + L +S +T + LK+ +
Sbjct: 626 -----------EGAAMLTCYSRDTGTPKWSDRVPKCALKY-------------------E 655
Query: 2258 KCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
C P ++ G+ +++ C+ G+ L+G +TC Q+ P C+
Sbjct: 656 PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 715
Score = 142 bits (359), Expect = 5e-33
Identities = 170/673 (25%), Positives = 249/673 (36%), Gaps = 112/673 (16%)
Query: 1564 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
+C P +G TD G T T+ CDSGY++ ++ C+ G +PSW+ PSC
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGT--RPSWNGETPSCM 232
Query: 1624 APCGGQ-YTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ---------- 1672
A CGG + + G ++SP C + I + + F
Sbjct: 233 ASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMV 292
Query: 1673 ----TALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFH 1728
+ L+ + D R L S + S E L +N +LL ++ R F
Sbjct: 293 RSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFA 352
Query: 1729 -FVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGS---TALHCQS 1784
F+ T+D E+ G++ F C PGY L+ A+ C
Sbjct: 353 PFLAHGNVTTTDP----------------EYRPGALATFSCLPGYALEPPGPPNAIEC-- 394
Query: 1785 VPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQ 1844
V WNDT P+C C G ++ G +LSP +P+ Y +C+W + V E I +Q
Sbjct: 395 VDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQ 454
Query: 1845 VISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVA---- 1900
V + D L + DG +A L G L S+ L L FQ+
Sbjct: 455 V-EILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGL 513
Query: 1901 AAGFHLEYKTVGLA-ACQEPALPS---NSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISC 1956
GF L +K V C E P + GD + VL++QCEPGY L G ++C
Sbjct: 514 GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGD-LIRGTVLTYQCEPGYELLGSDILTC 572
Query: 1957 MPGTVRRWNYPSPLC--IATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAH 2014
W+ P C I TC PG N P+G +H
Sbjct: 573 QWDL--SWSAAPPACQKIMTCAD--------------PGEIANGHRTASDAGFPVG--SH 614
Query: 2015 IQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQ 2074
+Q Y P G L A + T + D +
Sbjct: 615 VQ-------------------YRCLP------GYSLEGAAMLTCYSR------DTGTPKW 643
Query: 2075 GFKLAYQAYELQNCPDPPPFQNGY--MINSDYSVGQSVSFECYPGYILIGHPVLTCQHGI 2132
++ A + + C +P +NGY + Y G+S+ F CY G+ LIG +TC G
Sbjct: 644 SDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGH 703
Query: 2133 NRNWNYPFPRCDAPCGYNVTSQNGTI-----YSPGFPDEYPILKDCIWL---ITVPPGHG 2184
W P C Y N + P E L I L + + G G
Sbjct: 704 PSQWTSQPPLCKV--AYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSG 761
Query: 2185 VYINFTLLQTEAV 2197
VYI +T LQ +++
Sbjct: 762 VYIYYTKLQGKSL 774
Score = 133 bits (334), Expect = 4e-30
Identities = 128/449 (28%), Positives = 182/449 (40%), Gaps = 49/449 (10%)
Query: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
+CG P G + T + G + C GY L+G L C+ G SW+ P C
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICL--NGTRPSWNGETPSCM 232
Query: 204 AEGACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFL 262
A +CGGT+ T I SP N C W I A G + L F L+E D L
Sbjct: 233 A--SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 263 EISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGV 322
+ +P SPVI + D R +AQ S V
Sbjct: 291 MVRSGGSPL---------SPVIYDSDM------DDVPERGLISDAQ----------SLYV 325
Query: 323 KMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVL 382
++L + +LS A D C P + R GA FSC Y L
Sbjct: 326 ELLSETPANPL--LLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYAL 383
Query: 383 QGS---KSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
+ +I C TE W+D P C+A CG L P+GV+ SP++P Y CV
Sbjct: 384 EPPGPPNAIECVDPTEP--HWNDTEPACKAM-CGGELSEPAGVVLSPDWPQSYSPGQDCV 440
Query: 440 WVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
W + + +K I L E + G D LT+ D G + VL L G ++S
Sbjct: 441 WGVHVQE-EKRILLQVEILNVREG-DMLTLFDGD--GPSARVLAQLRGPQPRRRLLSSGP 496
Query: 500 QMWLHLQSDDSIGSP----GFKAVYQEIEKGG-CGDPGIPAYGKRTGS--SFLHGDTLTF 552
+ L Q+ +P GF ++E+ + C + P +G RT S + G LT+
Sbjct: 497 DLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTY 556
Query: 553 ECPAAFELVGERVITCQQNNQWSGNKPSC 581
+C +EL+G ++TCQ + WS P+C
Sbjct: 557 QCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Score = 115 bits (289), Expect = 6e-25
Identities = 155/688 (22%), Positives = 247/688 (35%), Gaps = 106/688 (15%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C P P +G + +D G F C+ Y LQG +++ C + T +W+ P C
Sbjct: 176 CGFPPRPAHGDVSVTDL-HPGGTATFHCDSGYQLQGEETLIC--LNGTRPSWNGETPSCM 232
Query: 409 ARTCGSNLRGPS-GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTL 467
A +CG + + G I SP N C WVI + + + L FE L+ D L
Sbjct: 233 A-SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRR-LHLHFERVSLDEDNDRL 290
Query: 468 TVGDAGKVGDTRSVLYVLTGSSVPDL-IVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKG 526
V G V+Y VP+ ++S + +++ L S+ ++ E+
Sbjct: 291 MVRSGGS--PLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEED 348
Query: 527 GCGDPGIPAYGK--RTGSSFLHGDTLTFECPAAFELVGE---RVITCQQNNQ--WSGNKP 579
C P + A+G T + G TF C + L I C + W+ +P
Sbjct: 349 RCFAPFL-AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEP 407
Query: 580 SCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFL 639
+C C + +G++LSP++P+ Y +CVW + + RI L +V + D L
Sbjct: 408 ACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR-EGDML 466
Query: 640 AVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECH 699
+ D VL G + +L SSG + L+FQ+
Sbjct: 467 TLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAP--------------------- 505
Query: 700 DPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPC 759
PG P G LG H + V + T P P
Sbjct: 506 -PGPPNPG--------LGQGFVLHFKE-------------------VPRNDTCPELPPPE 537
Query: 760 GGHLTASSGVIL---------PPGWPGYYKDSLHCEWIIE--AKPGHSIKITFDRFQTEV 808
G TAS G ++ PG+ D L C+W + A P KI
Sbjct: 538 WGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM-------T 590
Query: 809 NYDTLEVRDGPASSSPL---IGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYE 865
D E+ +G ++S +G + + G M ++ D +
Sbjct: 591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRV--P 648
Query: 866 SVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNH--QWN 921
L+ + CL+PG+P NG++ + + ++ F C G+ L + + C H QW
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 922 HALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI------EVSHGKGVQMIF-- 973
P C + + V P N I + G GV + +
Sbjct: 709 SQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTK 768
Query: 974 ----HTFHLESSHDYLLITEDGSFSEPV 997
F SH Y IT + FS P+
Sbjct: 769 LQGKSLFGFSGSHSYSPITVESDFSNPL 796
Score = 104 bits (260), Expect = 1e-21
Identities = 129/565 (22%), Positives = 204/565 (36%), Gaps = 47/565 (8%)
Query: 2256 LKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
L C PP ++ D G + C GY L G + L C ++ + G P+
Sbjct: 173 LLSCGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPS 230
Query: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDA 2375
C A C + + G I+SP G + TC W I+ + + + ++ D
Sbjct: 231 CMASC-GGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDR 289
Query: 2376 LEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA---PY 2432
L V G S SP++ + + S + LY+ ++ + +R+ A
Sbjct: 290 LMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 2433 CSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRM--VGHSNATCRRNPLGMYQWDSLTPL 2490
C G+ + C PGY + G NA +P + W+ P
Sbjct: 350 CFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH-WNDTEPA 408
Query: 2491 CQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQ------QATAVCQEDGLW 2544
C+A+ CG S G ++ +C G ++ + + V + D L
Sbjct: 409 CKAM-CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLT 467
Query: 2545 SNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2604
G P+ + + AQL R + S + Q PG G
Sbjct: 468 LFDGDGPSAR------VLAQLRGPQPRRRLLSSGPDLTLQ--FQAPPGPPNPGL------ 513
Query: 2605 ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTL--TVYGATAIFTCNTGYTLVGSHVRE 2662
G + + R +C L P G + + + G + C GY L+GS +
Sbjct: 514 --GQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILT 571
Query: 2663 CLANGLWSGSETRC-LAGHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVR 2719
C + WS + C C P I NGH S GF V Y+C PG+ L G ++
Sbjct: 572 CQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAML 631
Query: 2720 ICLQ----DHKWSGQTPVCV--PITCGHPGNPAHGFTN--GSEFNLNDVVNFTCNTGYLL 2771
C KWS + P C C +PG P +G+ + + + F C G+ L
Sbjct: 632 TCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFEL 691
Query: 2772 QGVSRAQCRSN--GQWSSPLPTCRV 2794
G C QW+S P C+V
Sbjct: 692 IGEVTITCVPGHPSQWTSQPPLCKV 716
Score = 97.4 bits (241), Expect = 2e-19
Identities = 137/572 (23%), Positives = 201/572 (35%), Gaps = 112/572 (19%)
Query: 31 NCGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVY 89
+CGG + G I SP C W+I E R+ L F +L+ED D L V
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVR 293
Query: 90 DGQPQQGNLKVRLSGFQLPS-SIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
G + +P ++S L + ++ + +E C P
Sbjct: 294 SGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAP 353
Query: 149 GEILKGVLHGT------RFNIGDKIRYSCLPGYILEGHAILTCI--VSPGNGASWDFPAP 200
+ HG + G +SCLPGY LE I V P W+ P
Sbjct: 354 F-----LAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTE-PHWNDTEP 407
Query: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYD 260
C+A CGG L + + SP +P Y DC W + + I L + EG D
Sbjct: 408 ACKA--MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-D 464
Query: 261 FLEISGTEAPSIW-LTGMNLPSP---VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
L + + PS L + P P ++SS L L F + G F +
Sbjct: 465 MLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLH---- 520
Query: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-GANVQFS 375
K +P +D CP+ PE G R S + G + +
Sbjct: 521 -----FKEVPR------------------NDTCPELPPPEWGWRTASHGDLIRGTVLTYQ 557
Query: 376 CEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
CE Y L GS +TCQ +WS P C+
Sbjct: 558 CEPGYELLGSDILTCQWDL----SWSAAPPACQK-------------------------- 587
Query: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
++T DP E+ G+ T + DAG + L G
Sbjct: 588 -----IMTCADPG----------EIANGHRTAS--DAGFPVGSHVQYRCLPG-------Y 623
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQE--IEKGGCGDPGIPAYGKRT--GSSFLHGDTLT 551
S+ L S D+ G+P + + ++ C +PG+P G +T + G++L
Sbjct: 624 SLEGAAMLTCYSRDT-GTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLR 682
Query: 552 FECPAAFELVGERVITCQQN--NQWSGNKPSC 581
F C FEL+GE ITC +QW+ P C
Sbjct: 683 FFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 92.0 bits (227), Expect = 9e-18
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 15/184 (8%)
Query: 2684 PDPIVNGHISGDGFSYRDTVV-YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI-TCGH 2741
P P + G R TV+ YQC PG+ L+G+ + C D WS P C I TC
Sbjct: 534 PPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCAD 593
Query: 2742 PGNPAHGFTNGSE--FNLNDVVNFTCNTGYLLQGVSRAQCRSNG----QWSSPLPTC--R 2793
PG A+G S+ F + V + C GY L+G + C S +WS +P C +
Sbjct: 594 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 653
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRS 2851
C +PG EN Q + ++ G S+ + C +GF L+G +TC+ W
Sbjct: 654 YEPCLNPGVPENGY---QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQ 710
Query: 2852 LPKC 2855
P C
Sbjct: 711 PPLC 714
Score = 87.8 bits (216), Expect = 2e-16
Identities = 90/359 (25%), Positives = 143/359 (39%), Gaps = 41/359 (11%)
Query: 2928 AHGSRLGDD--FKTKSLLRFSCEMGHQLR--GSPERTCLLNGS---WSGLQPVCEAVSCG 2980
AHG+ D ++ +L FSC G+ L G P ++ + W+ +P C+A+ CG
Sbjct: 356 AHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAM-CG 414
Query: 2981 NPGTPTNGMIVSSDGILFSSSVIYACWEGY---------KTSGLMTRHCTANGTWTGTAP 3031
+ G+++S D S W + + L R + G P
Sbjct: 415 GELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGP 474
Query: 3032 DCTIIS-CGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 3090
+++ P + G D T + +Q PG + + K+ N +
Sbjct: 475 SARVLAQLRGPQPRRRLLSSGPDLT----LQFQAPPGPPNPGLGQGFVLHFKEVPRNDT- 529
Query: 3091 PVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEI 3148
CP+ PP + G T D G+ ++Y C GY+L S IL+C+ W
Sbjct: 530 -------CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAP 582
Query: 3149 PQCLPVF-CGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT---- 3201
P C + C DPG A G S F S V ++C + L G++ C + T
Sbjct: 583 PACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPK 642
Query: 3202 WSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
WS P C + C +PG P G Q Y+ G ++ F C +G+ + G T TC+
Sbjct: 643 WSDRVPKCA-LKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 700
Score = 82.0 bits (201), Expect = 9e-15
Identities = 127/571 (22%), Positives = 196/571 (34%), Gaps = 125/571 (21%)
Query: 2858 ISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSH--WSGALPHCTG 2915
+SCG P PA+ ++ G + C L G +T +C + W+G P C
Sbjct: 174 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMA 233
Query: 2916 NNPGFC-----GDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL-------- 2962
+ G G +P G +G + + ++ + G +L ER L
Sbjct: 234 SCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAA--EGRRLHLHFERVSLDEDNDRLM 291
Query: 2963 LNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGI---LFSSSVIYACWEGYKTSGLMTRH 3019
+ S L PV + P G+I + + L S + +
Sbjct: 292 VRSGGSPLSPVIYDSDMDD--VPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 3020 C----TANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTS 3075
C A+G T T P+ PG LA ++ C PGY +E
Sbjct: 350 CFAPFLAHGNVTTTDPEYR------PGALA---------------TFSCLPGYALEPPGP 388
Query: 3076 AT-IRCTK--DGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSH 3132
I C + WN ++P CKA +C G V D+ S C+ G +
Sbjct: 389 PNAIECVDPTEPHWNDTEPACKA-MCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQE 447
Query: 3133 SA--ILSCEGRGVWKGEI------------------------------PQCLPVFCGDPG 3160
+L E V +G++ P F PG
Sbjct: 448 EKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPG 507
Query: 3161 IPAEGRLSGKSFTYK-----------------------------SEVFFQCKSPFILVGS 3191
P G G +K + + +QC+ + L+GS
Sbjct: 508 PPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGS 567
Query: 3192 SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS-RGYEVGSTVFFRCRKGYHI 3250
CQ D +WS P C TC DPG G + +S G+ VGS V +RC GY +
Sbjct: 568 DILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSL 625
Query: 3251 QGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF-------GYTLVYTC 3303
+G+ TC + T + ++ +P + E + V T G +L + C
Sbjct: 626 EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFC 685
Query: 3304 HPGFFLAGGSEHRTCKA--DMKWTGKSPVCK 3332
+ GF L G TC +WT + P+CK
Sbjct: 686 YEGFELI-GEVTITCVPGHPSQWTSQPPLCK 715
Score = 78.6 bits (192), Expect = 1e-13
Identities = 53/168 (31%), Positives = 72/168 (42%), Gaps = 13/168 (7%)
Query: 2879 GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-- 2936
G V+ Y C L+G+D CQ D WS A P C C DPG A+G R D
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC--QKIMTCADPGEIANGHRTASDAG 608
Query: 2937 FKTKSLLRFSCEMGHQLRGSPERTCLLNGS----WSGLQPVC--EAVSCGNPGTPTNG-M 2989
F S +++ C G+ L G+ TC + WS P C + C NPG P NG
Sbjct: 609 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 668
Query: 2990 IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTAN--GTWTGTAPDCTI 3035
+ S+ + C+EG++ G +T C WT P C +
Sbjct: 669 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 716
Score = 67.8 bits (164), Expect = 2e-10
Identities = 51/166 (30%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI-SCGHPGVPANAVLTGE--LFT 2877
G + Y C+ G+ LLGS LTC + W + P C I +C PG AN T F
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 610
Query: 2878 YGAVVHYSCRGSESLIGNDTRVCQE----DSHWSGALPHCTGNNPGFCGDPGTPAHG--S 2931
G+ V Y C SL G C WS +P C C +PG P +G +
Sbjct: 611 VGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEP-CLNPGVPENGYQT 669
Query: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN--GSWSGLQPVCE 2975
++ LRF C G +L G TC+ W+ P+C+
Sbjct: 670 LYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCK 715
Score = 48.1 bits (113), Expect = 2e-04
Identities = 43/143 (30%), Positives = 58/143 (40%), Gaps = 19/143 (13%)
Query: 1046 CDDPGVPAFSRRIGFHFG--VGDSLTFSCFLGYRLEGATKLTCLG--GGRRVWSAPLPRC 1101
C DPG A R G VG + + C GY LEGA LTC G WS +P+C
Sbjct: 591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 650
Query: 1102 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRT-RSFQLFEGDTLKV 1160
+ L+P P +N ++ +YK +AG+ + F+L T+
Sbjct: 651 ALK--------YEPCLNPGVP---ENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC 699
Query: 1161 YDGKDS---SSRPLGTFTKNELL 1180
G S S PL ELL
Sbjct: 700 VPGHPSQWTSQPPLCKVAYEELL 722
Score = 43.5 bits (101), Expect = 0.004
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 240 AEPGDTIALVFTDFQLEEGYDFL---------EISGTEAPSIWLTGMNLPSPVISSKNWL 290
A GD I +Q E GY+ L ++S + AP M P +
Sbjct: 543 ASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANG-- 600
Query: 291 RLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCP 350
H T+ G + Q++ L+ + S+D AL + C
Sbjct: 601 --HRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCL 658
Query: 351 DPGIPENG-RRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
+PG+PENG + + G +++F C + + L G +ITC V + W+ P+C+
Sbjct: 659 NPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC--VPGHPSQWTSQPPLCK 715
Score = 43.1 bits (100), Expect = 0.005
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQ--WSSPLPTCRV 2794
++CG P PAHG + ++ + F C++GY LQG C + + W+ P+C +
Sbjct: 174 LSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-M 232
Query: 2795 VNCSDPGFVENA 2806
+C G + NA
Sbjct: 233 ASCG--GTIHNA 242
Score = 37.0 bits (84), Expect = 0.35
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 5/90 (5%)
Query: 3008 EGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPG 3067
EG + T T T T T+P ++SCG P A+G TD T ++ C+ G
Sbjct: 147 EGGEEETTTTIITTTTVTTTVTSP-AYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSG 205
Query: 3068 YVMEAVTSATIRCTKDGR--WNPSKPVCKA 3095
Y ++ T+ C R WN P C A
Sbjct: 206 YQLQG--EETLICLNGTRPSWNGETPSCMA 233
Score = 33.9 bits (76), Expect = 3.0
Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 2486 SLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWS 2545
++T +SCG P P +G + + + C G++L+ + T +C S
Sbjct: 166 TVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEE--TLICLNGTRPS 223
Query: 2546 NKGKPPTC 2553
G+ P+C
Sbjct: 224 WNGETPSC 231
Score = 33.9 bits (76), Expect = 3.0
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 2821 GMSILYHCKKGFYLLGSSALTCMANGL---WDRSLPKCLAISCGHPGVPANAVL 2871
G + +HC G+ L G L C+ NG W+ P C+A SCG G NA L
Sbjct: 195 GGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPSCMA-SCG--GTIHNATL 244
Score = 33.5 bits (75), Expect = 3.9
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 4/75 (5%)
Query: 3201 TWSGIQPTCIDPAHN-TCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
T + + T PA+ +C P P G S G T F C GY +QG T CL
Sbjct: 159 TTTTVTTTVTSPAYLLSCGFPPRPAHG-DVSVTDLHPGGTATFHCDSGYQLQGEETLICL 217
Query: 3260 --ANLTWSGIQTECI 3272
+W+G C+
Sbjct: 218 NGTRPSWNGETPSCM 232
Score = 32.3 bits (72), Expect = 8.6
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 3487 GSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENS--NGQASFENPMYD 3541
G++A AIL+P +I+ G Y+Y + + K + H S ++ F NP+Y+
Sbjct: 742 GNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYE 798
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 193 bits (490), Expect = 3e-48
Identities = 150/501 (29%), Positives = 211/501 (42%), Gaps = 50/501 (9%)
Query: 2750 TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRH 2809
T+ EF + +N+ C GY + S C N W+S C+ +C +P N + H
Sbjct: 50 TDDFEFPIGTYLNYECRPGYSGRPFSII-CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAH 108
Query: 2810 GQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVP 2866
+ ++ I Y C KG+ L+GSS+ TC+ +G +WD P C I CG P
Sbjct: 109 ----VIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTI 164
Query: 2867 ANAVLTG---ELFTYGAVVHYSC----RGSE--SLIGNDTRVCQEDSH----WSGALPHC 2913
AN T E F YG+VV Y C RG + L+G + C WSG P C
Sbjct: 165 ANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 224
Query: 2914 TGNNPGFCGDPGTPAHGSRLGDD---FKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL 2970
P C P +G + D+ F ++ F C+ G ++G C W
Sbjct: 225 I--IPNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPE 281
Query: 2971 QPVCEAVSCGNPGTPTNGMIVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTG 3028
P C V C P + D FS V Y+C GY G HCT G W+
Sbjct: 282 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSP 340
Query: 3029 TAPDCTIISCGD-PGTLANG-IQFGTDFTFNKTVSYQCNPGYVMEAVTSA-TIRCTKDGR 3085
AP C + SC D G L NG + F + V + C+ G+ ++ +++ + +
Sbjct: 341 AAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 400
Query: 3086 WNPSKPVCKAVLCPQPPPVQNGTVEG-SDFRWGSSISYSCMDGYQLSHSAILSCEGRGV- 3143
WN S PVC+ C PP NG V +D GS I+YSC G++L + C G
Sbjct: 401 WNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNT 460
Query: 3144 --WKGEIPQCLPVFCGDPGIPAEGRLSGK---SFTYKSEVFFQCK------SPFILVGSS 3192
W + P C +FC +P GR +G Y EV + C F L+G S
Sbjct: 461 AHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGES 520
Query: 3193 --RRVCQ--ADGTWSGIQPTC 3209
RR + +G WS P C
Sbjct: 521 TIRRTSEPHGNGVWSSPAPRC 541
Score = 192 bits (489), Expect = 4e-48
Identities = 138/493 (27%), Positives = 205/493 (41%), Gaps = 47/493 (9%)
Query: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNG-SEFNLNDVVNF 2763
Y+C PG+ S+ ICL++ W+ C +C +P +P +G + + + +
Sbjct: 63 YECRPGYSGRPFSI-ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKY 121
Query: 2764 TCNTGYLLQGVSRAQCRSNGQ---WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEY 2820
+C GY L G S A C +G W + P C + C P + N E F Y
Sbjct: 122 SCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISR--EYFHY 179
Query: 2821 GMSILYHC------KKGFYLLGSSALTCMAN----GLWDRSLPKCLAISCGHPGVPANAV 2870
G + YHC KK F L+G ++ C + G+W P+C+ + P N +
Sbjct: 180 GSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGI 239
Query: 2871 LTGE---LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTP 2927
L + LF+ VV + C+ + G CQ + W LP C+ C P
Sbjct: 240 LVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR----VCQPPPDV 295
Query: 2928 AHGSRLG---DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGN-PG 2983
H R D+F + +SCE G+ LRGS C G WS P CE SC + G
Sbjct: 296 LHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLG 355
Query: 2984 TPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGD 3040
NG ++ + + V + C EG++ G +C G W + P C SC
Sbjct: 356 QLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCET 415
Query: 3041 PGTLANG-IQFGTDFTFNKTVSYQCNPGYVMEAVTSAT-IRCTKDGRWNPSKPVCKAVLC 3098
P NG + TD ++Y C G+ + +SA I W+ P+C+ + C
Sbjct: 416 PPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFC 475
Query: 3099 PQPPPVQNGTVEGS---DFRWGSSISYSC-------MDGYQLSHSAILSC---EGRGVWK 3145
P PP + NG G+ D +G +SY+C M + S I G GVW
Sbjct: 476 PNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWS 535
Query: 3146 GEIPQC-LPVFCG 3157
P+C LPV G
Sbjct: 536 SPAPRCELPVGAG 548
Score = 183 bits (464), Expect = 3e-45
Identities = 145/503 (28%), Positives = 208/503 (41%), Gaps = 66/503 (13%)
Query: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY 2641
G + C PGY + ++ C N W ++ C+ SC + P NG +
Sbjct: 58 GTYLNYECRPGYSGRPFSII-CLKNSVWTSAKDK--CKRKSCRNPPDPVNGMAHVIKDIQ 114
Query: 2642 GATAI-FTCNTGYTLVGSHVRECLANG---LWSGSETRCLAGHCGSPDPIVNGH---ISG 2694
+ I ++C GY L+GS C+ +G +W C CG P I NG IS
Sbjct: 115 FRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISR 174
Query: 2695 DGFSYRDTVVYQCNPG------FRLVGTSVRICLQDHK----WSGQTPVCVPITCGHPGN 2744
+ F Y V Y CN G F LVG C WSG P C+ P N
Sbjct: 175 EYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPN 234
Query: 2745 PAHGFT---NGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPG 2801
+G N S F+LN+VV F C G+ ++G S +C++ +W LP+C V C P
Sbjct: 235 VENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV-CQPPP 293
Query: 2802 FVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISC- 2860
V +A R Q ++F G + Y C+ G+ L GS+ L C G W + P+C SC
Sbjct: 294 DVLHAER--TQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCD 351
Query: 2861 --------GHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVC---QEDSHWSGA 2909
GH P N L GA V + C L G+ C +S W+ +
Sbjct: 352 DFLGQLPNGHVLFPLNLQL-------GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSS 404
Query: 2910 LPHCTGNNPGFCGDPGTPAHGS-RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGS-- 2966
+P C + C P P +G + D S + +SC GH+L G C+L+G+
Sbjct: 405 VPVCERKS---CETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTA 461
Query: 2967 -WSGLQPVCEAVSCGNPGTPTNGMIVSS--DGILFSSSVIYACWEGYKTSGL-------- 3015
WS P+C+ + C NP NG + I + V Y C + + G+
Sbjct: 462 HWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTC-DPHPDRGMTFNLIGES 520
Query: 3016 ---MTRHCTANGTWTGTAPDCTI 3035
T NG W+ AP C +
Sbjct: 521 TIRRTSEPHGNGVWSSPAPRCEL 543
Score = 165 bits (418), Expect = 7e-40
Identities = 144/510 (28%), Positives = 214/510 (41%), Gaps = 66/510 (12%)
Query: 2511 EFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEH 2568
EF + + + YEC G+ S + + +C ++ +W++ CK +C P H
Sbjct: 54 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWTSA--KDKCKRKSCRNPPDPVNGMAH 108
Query: 2569 VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDER-PSCRVISCGSLS 2627
VI + ++ +Q+ SC GY L G C +G I D + P C I CG
Sbjct: 109 VIKDI------QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPP 162
Query: 2628 FPPNGNKIGTLTV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSET 2674
NG+ YG+ + CN G + LVG C + G+WSG
Sbjct: 163 TIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAP 222
Query: 2675 RCLAGHCGSPDPIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
+C+ + +P + NG + D FS + V ++C PGF + G S C +KW +
Sbjct: 223 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPEL 282
Query: 2732 PVCVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSP 2788
P C + C P + H + F+ V ++C GY L+G + C G WS
Sbjct: 283 PSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPA 341
Query: 2789 LPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-- 2846
P C V +C D + +G FP + + G + + C +GF L GSSA C+ G
Sbjct: 342 APRCEVKSCDD---FLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 398
Query: 2847 -LWDRSLPKCLAISCGHPGVPANA---VLTGELFTYGAVVHYSCRGSESLIGNDTRVC-- 2900
LW+ S+P C SC P VP N V+T G+ ++YSC LIG+ + C
Sbjct: 399 SLWNSSVPVCERKSCETPPVPVNGMVHVITD--IHVGSRINYSCTTGHRLIGHSSAECIL 456
Query: 2901 -QEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLG---DDFKTKSLLRFSCEMGHQLRGS 2956
+HWS P C FC +P +G G D + ++C+ H RG
Sbjct: 457 SGNTAHWSMKPPIC---QQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCD-PHPDRGM 512
Query: 2957 P-----ERTCLL------NGSWSGLQPVCE 2975
E T NG WS P CE
Sbjct: 513 TFNLIGESTIRRTSEPHGNGVWSSPAPRCE 542
Score = 155 bits (392), Expect = 7e-37
Identities = 128/438 (29%), Positives = 185/438 (42%), Gaps = 43/438 (9%)
Query: 2928 AHGSRLGDDFKTK--SLLRFSCEMGHQLRGSP-ERTCLLNGSWSGLQPVCEAVSCGNPGT 2984
A + L DDF+ + L + C G+ G P CL N W+ + C+ SC NP
Sbjct: 44 ARPTNLTDDFEFPIGTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPD 101
Query: 2985 PTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDP 3041
P NGM I F S + Y+C +GY+ G + C +G W P C I CG P
Sbjct: 102 PVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLP 161
Query: 3042 GTLANGIQFGTDFT--------FNKTVSYQCNPG----YVMEAVTSATIRCT-KD---GR 3085
T+ANG DFT + V+Y CN G V E V +I CT KD G
Sbjct: 162 PTIANG-----DFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGI 216
Query: 3086 WNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGSSISYSCMDGYQLSHSAILSCEGRG 3142
W+ P C PP V+NG + + F + + C G+ + + + C+
Sbjct: 217 WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALN 276
Query: 3143 VWKGEIPQCLPVFCGDPGI-PAEGRLSGK-SFTYKSEVFFQCKSPFILVGSSRRVCQADG 3200
W+ E+P C V P + AE K +F+ EVF+ C+ + L GS+ C G
Sbjct: 277 KWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQG 336
Query: 3201 TWSGIQPTCIDPAHNTCPD-PGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC- 3258
WS P C +C D G G ++G+ V F C +G+ ++GS+ C
Sbjct: 337 DWSPAAPRC---EVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCV 393
Query: 3259 LANL--TWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHR 3316
LA + W+ C +C P P + V I G + Y+C G L G S
Sbjct: 394 LAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAE 453
Query: 3317 TCKA--DMKWTGKSPVCK 3332
+ W+ K P+C+
Sbjct: 454 CILSGNTAHWSMKPPICQ 471
Score = 154 bits (388), Expect = 2e-36
Identities = 130/444 (29%), Positives = 192/444 (43%), Gaps = 61/444 (13%)
Query: 2454 SKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTG---N 2510
S++ Y C GYR++G S+ATC + + WD+ TP+C + CG+P + NG FT
Sbjct: 117 SQIKYSCPKGYRLIGSSSATCIISGNTVI-WDNKTPVCDRIICGLPPTIANGDFTSISRE 175
Query: 2511 EFTLDSKVVYECHEG------FKL--ESSQQATAVCQEDGLWSNKGKPPTC-KPVAC--P 2559
F S V Y C+ G F+L E S T+ + G+WS G P C P C P
Sbjct: 176 YFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWS--GPAPQCIIPNKCTPP 233
Query: 2560 SIEAQLSEHVIWRLVSG--SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPS 2617
++E + LVS SL V C PG+ ++G ++CQA W E P
Sbjct: 234 NVENGI-------LVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWE--PELP- 283
Query: 2618 CRVISCGSLSFPPNGNKIGTLTVY-------GATAIFTCNTGYTLVGSHVRECLANGLWS 2670
SC + PP T G ++C GY L GS C G WS
Sbjct: 284 ----SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWS 339
Query: 2671 GSETRCLAGHCGS-PDPIVNGHISGD-GFSYRDTVVYQCNPGFRLVGTSVRICL---QDH 2725
+ RC C + NGH+ V + C+ GF+L G+S C+ +
Sbjct: 340 PAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES 399
Query: 2726 KWSGQTPVCVPITCGHPGNPAHGFTNG-SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNG- 2783
W+ PVC +C P P +G + ++ ++ +N++C TG+ L G S A+C +G
Sbjct: 400 LWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGN 459
Query: 2784 --QWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCK------KGFYLL 2835
WS P C+ + C +P + N RH + YG + Y C F L+
Sbjct: 460 TAHWSMKPPICQQIFCPNPPAILNG-RHTGTPLGD-IPYGKEVSYTCDPHPDRGMTFNLI 517
Query: 2836 GSSALTCMA----NGLWDRSLPKC 2855
G S + + NG+W P+C
Sbjct: 518 GESTIRRTSEPHGNGVWSSPAPRC 541
Score = 124 bits (311), Expect = 2e-27
Identities = 145/574 (25%), Positives = 210/574 (36%), Gaps = 101/574 (17%)
Query: 2258 KCQPPPAVPQAEM--LTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
+C P +P A LT+D +F IG ++ Y+C PGY+ I+ K S +
Sbjct: 34 QCNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTSAKDKCKR 93
Query: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDA 2375
+ P + V G + VI F SQ + K +
Sbjct: 94 KSCRNPPDPV-NGMAHVI-----KDIQFRSQI------------------KYSCPKGYRL 129
Query: 2376 LEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSL 2435
+ G S ++SGN N T +++ C L
Sbjct: 130 I-------GSSSATCIISGNTVIWDNKTPVCDRI----------------------ICGL 160
Query: 2436 THPLKNGGI--LNRTAGAVGSKVHYFCKPG------YRMVGHSNATCRRNPLGMYQWDSL 2487
+ NG ++R GS V Y C G + +VG + C + W
Sbjct: 161 PPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGP 220
Query: 2488 TPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 2544
P C + P + NG + F+L+ V + C GF ++ CQ W
Sbjct: 221 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVK--CQALNKW 278
Query: 2545 SNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN-EYGAQVLLSCSPGYYLEGWRLLRC 2603
+ + P+C V P + +E R N G +V SC PGY L G L C
Sbjct: 279 --EPELPSCSRVCQPPPDVLHAE----RTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHC 332
Query: 2604 QANGTWNIGDERPSCRVISCGS-LSFPPNGNKIGTLTV-YGATAIFTCNTGYTLVGSHVR 2661
G W+ P C V SC L PNG+ + L + GA F C+ G+ L GS
Sbjct: 333 TPQGDWS--PAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSAS 390
Query: 2662 ECLANG---LWSGSETRCLAGHCGSPDPIVNG--HISGDGFSYRDTVVYQCNPGFRLVGT 2716
C+ G LW+ S C C +P VNG H+ D + Y C G RL+G
Sbjct: 391 YCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITD-IHVGSRINYSCTTGHRLIGH 449
Query: 2717 SVRICL---QDHKWSGQTPVCVPITCGHPG---NPAHGFTNGSEFNLNDVVNFTC----N 2766
S C+ WS + P+C I C +P N H T + V++TC +
Sbjct: 450 SSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPD 509
Query: 2767 TGYLLQGVSRAQCR------SNGQWSSPLPTCRV 2794
G + + R NG WSSP P C +
Sbjct: 510 RGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCEL 543
Score = 103 bits (258), Expect = 2e-21
Identities = 135/518 (26%), Positives = 199/518 (38%), Gaps = 97/518 (18%)
Query: 2257 KKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQ-LQFEGSLPT 2315
K C+ PP P M D + +KY C GY L+G+ TC +S + ++ P
Sbjct: 94 KSCRNPPD-PVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPV 152
Query: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDA 2375
C+ + G P N S + Y V T+
Sbjct: 153 CDR---------------IICGLPPTIANGDFTS----ISREYFHYGSVVTYHCNL---- 189
Query: 2376 LEVFDGSSGQSPLLVVLSGNHTEQSNF-TSRSNQLYLRWSTDHATSKKGFKIRYAAPYCS 2434
GS G+ +V E S + TS+ +Q+ + WS AP C
Sbjct: 190 -----GSRGKKVFELV-----GEPSIYCTSKDDQVGI-WSGP-------------APQCI 225
Query: 2435 L----THPLKNGGIL---NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSL 2487
+ T P GIL NR+ ++ V + C+PG+ M G S+ C+ + +W+
Sbjct: 226 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQ----ALNKWEPE 281
Query: 2488 TPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 2544
P C V C P + T + F+ +V Y C G+ L S C G W
Sbjct: 282 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLH--CTPQGDW 338
Query: 2545 SNKGKPPTCKPVACPSIEAQL-SEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRC 2603
S P C+ +C QL + HV++ L + GA+V C G+ L+G C
Sbjct: 339 SPAA--PRCEVKSCDDFLGQLPNGHVLFPLNL----QLGAKVDFVCDEGFQLKGSSASYC 392
Query: 2604 QANG---TWNIGDERPSCRVISCGSLSFPPNGN-KIGTLTVYGATAIFTCNTGYTLVGSH 2659
G WN P C SC + P NG + T G+ ++C TG+ L+G
Sbjct: 393 VLAGMESLWN--SSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHS 450
Query: 2660 VRECLANG---LWSGSETRCLAGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNP---- 2709
EC+ +G WS C C +P I+NG +G Y V Y C+P
Sbjct: 451 SAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDR 510
Query: 2710 --GFRLVGTS-VRICLQDH---KWSGQTPVC-VPITCG 2740
F L+G S +R + H WS P C +P+ G
Sbjct: 511 GMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVGAG 548
Score = 81.6 bits (200), Expect = 1e-14
Identities = 125/519 (24%), Positives = 190/519 (36%), Gaps = 101/519 (19%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTCQ-HGINRNWNYPFPRC 2143
++C +PP NG + D + + C GY LIG TC G W+ P C
Sbjct: 94 KSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Query: 2144 DAP-CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
D CG T NG S EY + G + F L+ ++
Sbjct: 154 DRIICGLPPTIANGDFTS--ISREYFHYGSVVTYHCNLGSRGKKV-FELVGEPSIYCTSK 210
Query: 2198 NDYIAVWDGPDQN----------SPQLGVF-SGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
+D + +W GP + + G+ S N +L +S V + F G
Sbjct: 211 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFGMKGP 267
Query: 2247 FVLNFHAFQL---------KKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
+ A + CQPPP V AE D D+F G V Y C PGY L G+
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
L C + Q + + P CE + + + +G +L P
Sbjct: 328 TYLHC--TPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP-------------------L 366
Query: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
N + VD F ++ F G S VL+G + W++
Sbjct: 367 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMES--------------LWNSS 404
Query: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRR 2476
++ P + H + T VGS+++Y C G+R++GHS+A C
Sbjct: 405 VPVCERKSCETPPVPVNGMVHVI--------TDIHVGSRINYSCTTGHRLIGHSSAECIL 456
Query: 2477 NPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTG---NEFTLDSKVVYECHE------GFK 2527
+ W P+CQ + C P + NG TG + +V Y C F
Sbjct: 457 SG-NTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFN 515
Query: 2528 L--ESSQQATAVCQEDGLWSNKGKPPTCK-PVACPSIEA 2563
L ES+ + T+ +G+WS+ P C+ PV S +A
Sbjct: 516 LIGESTIRRTSEPHGNGVWSSPA--PRCELPVGAGSHDA 552
Score = 78.2 bits (191), Expect = 1e-13
Identities = 103/438 (23%), Positives = 165/438 (37%), Gaps = 88/438 (20%)
Query: 1562 REACFDPGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
R++C +P + +NG V D + S I Y C GY+++ SS TC+I + WD P
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGN-TVIWDNKTP 151
Query: 1621 SCNAP-CGGQYTGSEG--VVLSPNYPHNYTAGQICLYSITV----PKEFVVFGQFAYFQT 1673
C+ CG T + G +S Y H G + Y + K F + G+ + + T
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREYFHY---GSVVTYHCNLGSRGKKVFELVGEPSIYCT 208
Query: 1674 ALNDLAELFDGTHAQARLLSSLS------GSHSGETLPLATSNQILLRFSAKSGASARG- 1726
+ +D ++ G Q + + + G + L + N+++ F + G +G
Sbjct: 209 SKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVV-EFRCQPGFGMKGP 267
Query: 1727 FHFVYQAVPRTSDT--QCSSVPEP-------RYGRRIGSEFSAGSIVRFECNPGYLLQGS 1777
H QA+ + CS V +P +R FS G V + C PGY L+GS
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 1778 TALHCQSVPNALAQWNDTIPSCVVPCSGNFTQR--RGTILSPGYPEPYGNNLNCIWKIIV 1835
T LHC W+ P C V +F + G +L P NL K+
Sbjct: 328 TYLHC----TPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFP-------LNLQLGAKVDF 376
Query: 1836 TEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQS 1895
G Q++ GS + V A + S N S
Sbjct: 377 VCDEGFQLK--------------------------GSSASYCVLAGMESLWN-------S 403
Query: 1896 DISVAAAGFHLEYKTVGLAACQEPALPSNS-IKIGDRYMVNDVLSFQCEPGYTLQGRSHI 1954
+ V +C+ P +P N + + V +++ C G+ L G S
Sbjct: 404 SVPVCER-----------KSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSA 452
Query: 1955 SC-MPGTVRRWNYPSPLC 1971
C + G W+ P+C
Sbjct: 453 ECILSGNTAHWSMKPPIC 470
Score = 60.5 bits (145), Expect = 3e-08
Identities = 97/443 (21%), Positives = 154/443 (34%), Gaps = 71/443 (16%)
Query: 1241 VLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPY 1299
+ YSC GY + GS++ TC +SG+ +WD P C G +G S +
Sbjct: 119 IKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFH 178
Query: 1300 DNNL---HCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPE 1356
++ HC + ++ T D + +W GP I+ + + +
Sbjct: 179 YGSVVTYHCNLGSRGKKVFELVGEPSIYCTS-KDDQVGIWSGPAPQCIIPNKCTPPNVEN 237
Query: 1357 DIHSTFN-SLTLQFDSDFFISKSGFSIQFSTSI---AATCNDPGMP-------------- 1398
I + N SL + F + GF ++ + + A +P +P
Sbjct: 238 GILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLH 297
Query: 1399 -QNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLT 1457
+ R D+ G V + C+PGY L+G + C + W P P C +
Sbjct: 298 AERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD---WSPAAPRCEVKSCDDFL 354
Query: 1458 G--PAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSN 1515
G P G +L P + ++ DFV F+ SY L E ++
Sbjct: 355 GQLPNGHVLFP-----------LNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 403
Query: 1516 SPLIGSYQGSQAP-----------------ERIE-SSGNSLFLAFRSDASVGLSGFAIEF 1557
S + + + P RI S L S A LSG +
Sbjct: 404 SVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHW 463
Query: 1558 KEKP----REACFDPGNIMNGTRVGT---DFKLGSTITYQCD------SGYKILDPSSIT 1604
KP + C +P I+NG GT D G ++Y CD + ++ S+I
Sbjct: 464 SMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIR 523
Query: 1605 CVIGADGKPSWDQVLPSCNAPCG 1627
G W P C P G
Sbjct: 524 RTSEPHGNGVWSSPAPRCELPVG 546
Score = 56.6 bits (135), Expect = 4e-07
Identities = 98/444 (22%), Positives = 151/444 (34%), Gaps = 103/444 (23%)
Query: 695 QNECHDPGIPINGRRFGDRFL-LGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVP 753
+ C +P P+NG + + S + + C G+ + GS S TCI+ V+W + P
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGY-RLIGSSSATCIISGNTVIWDNKTP 151
Query: 754 RCE-APCGGHLTASSGVILPPGWPGYYKDSL---HCEWIIEAKPGHSIKITFDRFQTEVN 809
C+ CG T ++G ++ S+ HC G K F+
Sbjct: 152 VCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNL------GSRGKKVFELVGEPSI 205
Query: 810 YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTL 869
Y T S +G + G APQ +I
Sbjct: 206 YCT--------SKDDQVGIWSG-PAPQCII------------------------------ 226
Query: 870 ESDSCLDP----GIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 925
+ C P GI V+ +R F + V F C PG+ + + C+ ++W LP
Sbjct: 227 -PNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELP 283
Query: 926 SCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHT----FHLESS 981
SC +C +F P Q +F++ + L S
Sbjct: 284 SCSRVCQPPPDVLHAERTQRDKDNFSPG----------------QEVFYSCEPGYDLRGS 327
Query: 982 HDYLLITEDGSFSEPVARL-------------TGSVL-PHTIKAGLFGNFTAQLRF-ISD 1026
YL T G +S R G VL P ++ G +F F +
Sbjct: 328 -TYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKG 386
Query: 1027 FSISY-------EGFNITFSEYDLEPCDDPGVPAFSR-RIGFHFGVGDSLTFSCFLGYRL 1078
S SY +N + + + C+ P VP + VG + +SC G+RL
Sbjct: 387 SSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRL 446
Query: 1079 EGATKLTC-LGGGRRVWSAPLPRC 1101
G + C L G WS P C
Sbjct: 447 IGHSSAECILSGNTAHWSMKPPIC 470
Score = 55.8 bits (133), Expect = 7e-07
Identities = 69/288 (23%), Positives = 112/288 (38%), Gaps = 74/288 (25%)
Query: 1392 CNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C P + +NG D+R + V F+C PG+ ++G + + C LN W+P+ P+C
Sbjct: 230 CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNK---WEPELPSC 285
Query: 1449 IAACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYD 1504
C P +L Q + PG+E +F ++ EP YD
Sbjct: 286 SRVC-----QPPPDVLHAERTQRDKDNFSPGQE---------------VF--YSCEPGYD 323
Query: 1505 -----FLHIYEGEDSNSPLIGSYQGSQAPERIES--SGNSLF---------LAFRSDASV 1548
+LH D SP + + + +G+ LF + F D
Sbjct: 324 LRGSTYLHCTPQGDW-SPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGF 382
Query: 1549 GLSGFAIEF-----------KEKP---REACFDPGNIMNG-TRVGTDFKLGSTITYQCDS 1593
L G + + P R++C P +NG V TD +GS I Y C +
Sbjct: 383 QLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTT 442
Query: 1594 GYKILDPSSITCVIGADGKPSWDQVLPSC------NAPC--GGQYTGS 1633
G++++ SS C++ + W P C N P G++TG+
Sbjct: 443 GHRLIGHSSAECILSGN-TAHWSMKPPICQQIFCPNPPAILNGRHTGT 489
Score = 52.8 bits (125), Expect = 6e-06
Identities = 70/307 (22%), Positives = 108/307 (35%), Gaps = 62/307 (20%)
Query: 1217 KCEDPGIPNYGYRIRDEGHF--TDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
KC P + N G + D + VV + C PG+ M G + + C + ++ W+ LPSC
Sbjct: 229 KCTPPNVEN-GILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNK--WEPELPSC 285
Query: 1275 IAEC---GGQIHAATSGR-------------ILSPGYPAPYDNNLHCT----WIIEADPG 1314
C +HA + R PGY LHCT W A
Sbjct: 286 SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Query: 1315 KTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFF 1374
+ S + H + P++ + G+ + F L+ S +
Sbjct: 346 EVKSCDDFLGQLPNGHVLF-----PLNLQL------GAKVDFVCDEGFQ---LKGSSASY 391
Query: 1375 ISKSGFSIQFSTSIAA----TCNDPGMPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAK 1429
+G +++S+ +C P +P NG G + + C G++L G +
Sbjct: 392 CVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSS 451
Query: 1430 ITCVQLNNRFFWQPDPPTC--------IAACGGNLTG-PAGVILSPNYPQPYPPGKECDW 1480
C+ N W PP C A G TG P G I P GKE +
Sbjct: 452 AECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDI---------PYGKEVSY 502
Query: 1481 RVKVNPD 1487
+PD
Sbjct: 503 TCDPHPD 509
Score = 51.6 bits (122), Expect = 1e-05
Identities = 106/458 (23%), Positives = 157/458 (34%), Gaps = 102/458 (22%)
Query: 144 TCGNPGEILKGVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+C NP + + G+ H + +I+YSC GY L G + TCI+S GN WD P C
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIIS-GNTVIWDNKTPVC 153
Query: 203 RAEGACG---GTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGY 259
CG G +SIS +F C L G + F+L
Sbjct: 154 -DRIICGLPPTIANGDFTSISREYFHYGSVVTYHCN---LGSRGKKV------FELVGEP 203
Query: 260 DFLEISGTEAPSIWLTGMNLPSPVISSK----NWLRLHFTSDSNHRRKGFNAQFQVKKAI 315
S + IW P +I +K N SD+ + F + + +
Sbjct: 204 SIYCTSKDDQVGIW--SGPAPQCIIPNKCTPPNVENGILVSDN-------RSLFSLNEVV 254
Query: 316 ELKSR-GVKMLPSKDGSH-KNSVLSQGGVAL--VSDMC---PDPGIPENGRRAGSDFSRV 368
E + + G M K SH K L++ L S +C PD E +R +FS
Sbjct: 255 EFRCQPGFGM---KGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFS-P 310
Query: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNL-RGPSGVITSPN 427
G V +SCE Y L+GS + C + WS P C ++C L + P+G + P
Sbjct: 311 GQEVFYSCEPGYDLRGSTYLHCTPQGD----WSPAAPRCEVKSCDDFLGQLPNGHVLFP- 365
Query: 428 YPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTG 487
L+ G V D G + L G
Sbjct: 366 ------------------------------LNLQLGAKVDFVCDEG---------FQLKG 386
Query: 488 SSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLH- 546
SS +++ +W + E+ C P +P G + +H
Sbjct: 387 SSASYCVLAGMESLW--------------NSSVPVCERKSCETPPVPVNGMVHVITDIHV 432
Query: 547 GDTLTFECPAAFELVGERVITC---QQNNQWSGNKPSC 581
G + + C L+G C WS P C
Sbjct: 433 GSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 49.7 bits (117), Expect = 5e-05
Identities = 91/441 (20%), Positives = 140/441 (31%), Gaps = 97/441 (21%)
Query: 1391 TCNDPGMPQNGTRYG-DSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC- 1448
+C +P P NG + + + + C GY+L G + TC+ N W P C
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHI 1508
CG PP N DF S ++ H
Sbjct: 155 RIICG------------------LPP-------TIANGDFT----------SISREYFHY 179
Query: 1509 YEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGL-SGFAIEFKEKPREACF- 1566
+ L GS+ + E G D VG+ SG P C
Sbjct: 180 GSVVTYHCNL-----GSRGKKVFELVGEPSIYCTSKDDQVGIWSG--------PAPQCII 226
Query: 1567 ----DPGNIMNGTRVGTD---FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVL 1619
P N+ NG V + F L + ++C G+ + PS + C W+ L
Sbjct: 227 PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC----QALNKWEPEL 282
Query: 1620 PSCNAPCGGQYTGSEGVVLSPNYPH---------NYTAGQICLYSITVPKEFVVFGQFAY 1670
PSC+ C P+ H N++ GQ YS + + G
Sbjct: 283 PSCSRVCQP----------PPDVLHAERTQRDKDNFSPGQEVFYS--CEPGYDLRGSTYL 330
Query: 1671 FQTALNDLAELFDGTHAQA--RLLSSLSGSH--------SGETLPLATSNQILLRFSAKS 1720
T D + ++ L L H G + L+ S+ S
Sbjct: 331 HCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSAS 390
Query: 1721 GASARGFHFVY-QAVPRTSDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGST 1778
G ++ +VP C + P P G + ++ GS + + C G+ L G +
Sbjct: 391 YCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHS 450
Query: 1779 ALHCQSVPNALAQWNDTIPSC 1799
+ C N A W+ P C
Sbjct: 451 SAECILSGNT-AHWSMKPPIC 470
Score = 47.4 bits (111), Expect = 3e-04
Identities = 100/472 (21%), Positives = 162/472 (34%), Gaps = 104/472 (22%)
Query: 1714 LRFSAKSGASARGFHFVY-------QAVPRTSDTQCSSVPEPRYGR-RIGSEFSAGSIVR 1765
L + + G S R F + A + C + P+P G + + S ++
Sbjct: 61 LNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 1766 FECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV-VPC-------SGNFTQRRGTILSP 1817
+ C GY L GS++ C N + W++ P C + C +G+FT
Sbjct: 121 YSCPKGYRLIGSSSATCIISGNTVI-WDNKTPVCDRIICGLPPTIANGDFTSISREYFHY 179
Query: 1818 GYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTT 1877
G Y NL K + I + T ++ D + I G AP+ + T
Sbjct: 180 GSVVTYHCNLGSRGKKVFELVGEPSI----YCTSKD-DQVGIWSG---PAPQCIIPNKCT 231
Query: 1878 VPALLNS--TSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ-----EPALPSNSI---- 1926
P + N S+ L +++ K CQ EP LPS S
Sbjct: 232 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQP 291
Query: 1927 -----------KIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IAT 1974
+ D + + + CEPGY L+G +++ C P W+ +P C + +
Sbjct: 292 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQG--DWSPAAPRCEVKS 349
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQF-LNFSTEANHDFLEIQN 2033
C F G PN H+ F LN A DF+ +
Sbjct: 350 CDD-------------FLGQLPNG---------------HVLFPLNLQLGAKVDFVCDEG 381
Query: 2034 GPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPP 2093
Q G+ +L+ + + E ++C PP
Sbjct: 382 F---------QLKGSSASYCVLAGMESL--------------WNSSVPVCERKSCETPPV 418
Query: 2094 FQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
NG + + +D VG +++ C G+ LIGH C G +W+ P C
Sbjct: 419 PVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 46.6 bits (109), Expect = 4e-04
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 144 TCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
+C P + G++H T ++G +I YSC G+ L GH+ CI+S GN A W P C
Sbjct: 412 SCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILS-GNTAHWSMKPPIC 470
Query: 203 R 203
+
Sbjct: 471 Q 471
Score = 43.9 bits (102), Expect = 0.003
Identities = 93/461 (20%), Positives = 150/461 (32%), Gaps = 106/461 (22%)
Query: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
KNSV + C +P P NG + + +++SC Y L GS S TC
Sbjct: 80 KNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCI- 138
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIK 452
++ W + P+ C + G I + ++ + H V+T
Sbjct: 139 ISGNTVIWDNKTPV-----CDRIICGLPPTIANGDFTSISREYFHYGSVVTYH------- 186
Query: 453 LAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIG 512
+G GK ++ L G P + + DD +G
Sbjct: 187 --------------CNLGSRGKK------VFELVGE--PSIYCT---------SKDDQVG 215
Query: 513 SPGFKAVYQEIEKGGCGDP----GIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITC 568
A Q I C P GI R S F + + F C F + G + C
Sbjct: 216 IWSGPAP-QCIIPNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 569 QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFN 628
Q N+W PSC C +L + +N + PG +
Sbjct: 273 QALNKWEPELPSCSRVC-----QPPPDVLHAERTQRDKDNFS--------PGQEVF---- 315
Query: 629 DFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLAS---------SGHIV-------- 671
+ EP +D ++ T G +S ++ S +GH++
Sbjct: 316 -YSCEPGYD---LRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLG 371
Query: 672 -RLEFQSDHSTTGRGFNITYTTFGQNE--------------CHDPGIPINGR-RFGDRFL 715
+++F D +G + +Y E C P +P+NG
Sbjct: 372 AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIH 431
Query: 716 LGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE 756
+GS +++ C G + G S CIL WS P C+
Sbjct: 432 VGSRINYSCTTGH-RLIGHSSAECILSGNTAHWSMKPPICQ 471
Score = 38.1 bits (87), Expect = 0.16
Identities = 49/261 (18%), Positives = 91/261 (34%), Gaps = 28/261 (10%)
Query: 1565 CFDPGNIMNGTRVGTD---FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPS 1621
C P ++++ R D F G + Y C+ GY + + + C D W P
Sbjct: 289 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD----WSPAAPR 344
Query: 1622 CNAPCGGQYTGS--EGVVLSP-NYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDL 1678
C + G G VL P N +C + + A ++ N
Sbjct: 345 CEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSS 404
Query: 1679 AELFDGTHAQAR------LLSSLSGSHSGETLPLA--TSNQILLRFSAKSGASARGFHFV 1730
+ + + ++ ++ H G + + T ++++ SA+ S H+
Sbjct: 405 VPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWS 464
Query: 1731 YQAVPRTSDTQCSSVPEPRYGRRIGS---EFSAGSIVRFECNPG------YLLQGSTALH 1781
+ P C + P GR G+ + G V + C+P + L G + +
Sbjct: 465 MKP-PICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIR 523
Query: 1782 CQSVPNALAQWNDTIPSCVVP 1802
S P+ W+ P C +P
Sbjct: 524 RTSEPHGNGVWSSPAPRCELP 544
Score = 35.0 bits (79), Expect = 1.3
Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 9/72 (12%)
Query: 698 CHDPGIPINGRRFGDRF---LLGSSVSFHCDD----GFVKTQGSESITCILQD--GNVVW 748
C +P +NGR G G VS+ CD G ES + GN VW
Sbjct: 475 CPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVW 534
Query: 749 SSTVPRCEAPCG 760
SS PRCE P G
Sbjct: 535 SSPAPRCELPVG 546
Score = 34.7 bits (78), Expect = 1.7
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C P +P NG VG+ + +SC + L G S C ++ A WS PIC+
Sbjct: 413 CETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSMKPPICQ 471
Query: 409 ARTC 412
C
Sbjct: 472 QIFC 475
Score = 33.9 bits (76), Expect = 3.0
Identities = 59/261 (22%), Positives = 90/261 (34%), Gaps = 41/261 (15%)
Query: 696 NECHDPGIPINGRRFGDR---FLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTV 752
N+C P + NG D F L V F C GF +G + C + W +
Sbjct: 228 NKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGF-GMKGPSHVKCQALNK---WEPEL 282
Query: 753 PRCEAPCG-------GHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIK-ITFDRF 804
P C C T PG +Y CE PG+ ++ T+
Sbjct: 283 PSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYS----CE------PGYDLRGSTYLHC 332
Query: 805 QTEVNYDTLEVRDGPASSSPLIGEY-HGTQAPQFLISTGNFMYLL----FTTDNSRSSIG 859
+ ++ R S +G+ +G + G + + F S +S
Sbjct: 333 TPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYC 392
Query: 860 FLIHYESV------TLESDSCLDPGIPVNGHRHG-GDFGIRSTVTFSCDPGYTL---SDD 909
L ES+ E SC P +PVNG H D + S + +SC G+ L S
Sbjct: 393 VLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSA 452
Query: 910 EPLVCERNHQWNHALPSCDAL 930
E ++ W+ P C +
Sbjct: 453 ECILSGNTAHWSMKPPICQQI 473
Score = 33.5 bits (75), Expect = 3.9
Identities = 66/307 (21%), Positives = 101/307 (32%), Gaps = 92/307 (29%)
Query: 142 SHTCGNPGEILKGVLHGTR-------FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGAS 194
S C P + VLH R F+ G ++ YSC PGY L G L C
Sbjct: 286 SRVCQPPPD----VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQ----GD 337
Query: 195 WDFPAPFCRAEGACGGTLRGTSSSISSPH--FPSEYENNADCTWTILAEPGDTIALVFTD 252
W AP C + +C L + + H FP + A D
Sbjct: 338 WSPAAPRCEVK-SCDDFL----GQLPNGHVLFPLNLQLGAK-----------------VD 375
Query: 253 FQLEEGYDFLEISGTEAPSIWLTGM----NLPSPVISSKN-------------------- 288
F +EG+ ++ G+ A L GM N PV K+
Sbjct: 376 FVCDEGF---QLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHV 432
Query: 289 WLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDM 348
R++++ + HR G ++ + + S + +H S
Sbjct: 433 GSRINYSCTTGHRLIGHSS--------------AECILSGNTAH----WSMKPPICQQIF 474
Query: 349 CPDPGIPENGRRAGSDFSRV--GANVQFSCEDN------YVLQGSKSITCQRVTETLAAW 400
CP+P NGR G+ + G V ++C+ + + L G +I W
Sbjct: 475 CPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVW 534
Query: 401 SDHRPIC 407
S P C
Sbjct: 535 SSPAPRC 541
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 190 bits (483), Expect = 2e-47
Identities = 248/939 (26%), Positives = 376/939 (40%), Gaps = 115/939 (12%)
Query: 2453 GSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPL--CQAVSCGIPESPGNGSFT-- 2508
G++ Y C+PGYR +G+ CR+ +W +L PL CQ CG P G+FT
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-----EWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 2509 -GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSE 2567
GN F K VY C+EG++L + C DG W+N P C+ V C + A +
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQL-LGEINYRECDTDG-WTN--DIPICEVVKCLPVTAPENG 155
Query: 2568 HVIWRLVSGSLN-EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSL 2626
++ + +G V C+ GY +EG + C +G W+ E+P C ISC S
Sbjct: 156 KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISCKSP 213
Query: 2627 SFPPNGNKIGTLTVYGATAIF--TCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSP 2684
NG+ I +Y F CN GY C +G W + C C +P
Sbjct: 214 DV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLPS-CEEKSCDNP 270
Query: 2685 DPIVNGHISGDGFSYR--DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
I NG S +R D + YQC GF W P C C +P
Sbjct: 271 -YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDYP 328
Query: 2743 GNPAHGFTNGS------EFNLNDVVNFTCNTGYLLQGVS---RAQCRSNGQWSSPLPTCR 2793
G + + + ++ C+ + S C +G WS +P R
Sbjct: 329 DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPCLR 387
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL-LGSSALTCMANGLWDRSL 2852
C P ++EN QN F G SI C G+ L + +TCM NG W +
Sbjct: 388 --KCYFP-YLENGY---NQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2853 PKCLAI-SCGHPGVP-ANAVLTGELFTYG--AVVHYSCRGSESLIGNDTR---VCQEDSH 2905
P+C+ + +C + N ++ +TY Y C+ +T C +D
Sbjct: 440 PRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG- 498
Query: 2906 WSGALPHCTGNNPGFCGDPGTPAHGSRLGDD---FKTKSLLRFSCEMGHQLR-GSPERT- 2960
WS A P C + C P +R +D FK L + C G++ GS +
Sbjct: 499 WS-AQPTCIKS----CDIP--VFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSI 551
Query: 2961 -CLLNGSWSGLQPVCEAVSCGNPGTPTNGM-IVSSDGILFSSSVIYACWEGYKTSGLMTR 3018
C NG WS L P+C C P + + D + ++C G+ G +
Sbjct: 552 VCGYNG-WSDL-PICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSV 609
Query: 3019 HCTANGTWTGTAPDCTII-----SCGDPGTLANG---IQFGTDFTFNKTVSYQCNPGYVM 3070
C G +PD I SCG P L NG + ++ ++ V Y CNP ++M
Sbjct: 610 QC----YHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLM 665
Query: 3071 EAVTSATIRCTKDGRWNPSKPVC--KAVLCPQPPPVQNGTVEGSD--FRWGSSISYSCMD 3126
+ I+C DG W + PVC + C P +++G + S + +G S+ ++C +
Sbjct: 666 KGPNK--IQCV-DGEWT-TLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSE 721
Query: 3127 GYQLSHSAILSCEGRGVWKGEIPQCLPV----FCGDPG--IPAEGRLSGKSFTYKSEVFF 3180
+ + ++C GVW ++PQC+ + C I E + K F + S + +
Sbjct: 722 SFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRY 779
Query: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC-PDPGTPHFGIQNSSRGYEVGST 3239
+C+ G VC +G W + C C P P P+ ++ Y G
Sbjct: 780 RCRGK---EGWIHTVC-INGRWDP-EVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEK 834
Query: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQ--TECIPHACRQPETPAHADVRAI----DLP 3293
V C++ Y IQ TC + W I E IP C QP H + + +
Sbjct: 835 VSVLCQENYLIQEGEEITC-KDGRWQSIPLCVEKIP--CSQPPQIEHGTINSSRSSQESY 891
Query: 3294 TFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
G L YTC GF ++ +E TC KW+ P C+
Sbjct: 892 AHGTKLSYTCEGGFRISEENE-TTCYMG-KWS-SPPQCE 927
Score = 169 bits (428), Expect = 5e-41
Identities = 191/763 (25%), Positives = 298/763 (39%), Gaps = 100/763 (13%)
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
C C + + + ++ S G Q + C PGY G ++ C+ G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTV-------YGATAIFTCNTGYTLVGS-HVRECL 2664
+ C+ CG P GT T+ YG A++TCN GY L+G + REC
Sbjct: 75 NPLRKCQKRPCGH----PGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECD 130
Query: 2665 ANGLWSGSETRCLAGHCGSPDPIVNGHISGDG------FSYRDTVVYQCNPGFRLVGTSV 2718
+G W+ C C NG I + + V + CN G+++ G
Sbjct: 131 TDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEE 189
Query: 2719 RICLQDHKWSGQTPVCVPITCGHP----GNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
C D WS + P CV I+C P G+P + + N+ + CN GY
Sbjct: 190 MHCSDDGFWSKEKPKCVEISCKSPDVINGSP---ISQKIIYKENERFQYKCNMGYEYSER 246
Query: 2775 SRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA------IRHGQQNFPESFEYGMSILYHC 2828
A C +G W PLP+C +C +P ++ N I+H G I Y C
Sbjct: 247 GDAVCTESG-W-RPLPSCEEKSCDNP-YIPNGDYSPLRIKH---------RTGDEITYQC 294
Query: 2829 KKGFY-LLGSSALTCMANGLWDRSLPKCLAISCGHPGV------------PANAVLTGEL 2875
+ GFY + C + G W + P+C C +P + P V G+
Sbjct: 295 RNGFYPATRGNTAKCTSTG-WIPA-PRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 2876 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGD 2935
++Y H+ D C +D WS A+P + + HG +
Sbjct: 353 YSYYCDEHFETPSGSYW---DHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRK--- 405
Query: 2936 DFKTKSLLRFSCEMGHQL-RGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSD 2994
F + +C G+ L + TC+ NG WS +C +S
Sbjct: 406 -FVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISES 463
Query: 2995 GILFS--SSVIYACWEGY-----KTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTL-AN 3046
++ Y C GY +TSG +T C +G W+ P C I SC P + A
Sbjct: 464 QYTYALKEKAKYQCKLGYVTADGETSGSIT--CGKDG-WS-AQPTC-IKSCDIPVFMNAR 518
Query: 3047 GIQFGTDFTFNKTVSYQCNPGYVME-AVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQ 3105
T F N T+ Y+C+ GY T+ +I C +G W+ P+C C + P +
Sbjct: 519 TKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYEREC-ELPKID 575
Query: 3106 NGTV---EGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVF--CGDPG 3160
V + ++ G + +SC G+ + + C G+ ++P C CG P
Sbjct: 576 VHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPP 634
Query: 3161 IPAEGRLSGKS---FTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC 3217
G + K+ + + V + C F++ G ++ C DG W+ + P CI +TC
Sbjct: 635 ELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWTTL-PVCI-VEESTC 691
Query: 3218 PD-PGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL 3259
D P H Q SS Y G +V F C + + + G + TC+
Sbjct: 692 GDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI 734
Score = 169 bits (428), Expect = 5e-41
Identities = 279/1143 (24%), Positives = 430/1143 (37%), Gaps = 182/1143 (15%)
Query: 2256 LKKCQPPPAVPQAEM------LTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQF 2309
L+KCQ P + LT + FE G Y C+ GY L+G + + +
Sbjct: 77 LRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGE--INYRECDTDGW 134
Query: 2310 EGSLPTCE-AQC-PANEVRTG---SSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV 2364
+P CE +C P G SS + Y C+ K+E + +
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 2365 DTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGF 2424
D F S+++ +E+ S +SP V++G+ Q
Sbjct: 195 DGFWSKEKPKCVEI----SCKSP--DVINGSPISQ------------------------- 223
Query: 2425 KIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQW 2484
KI Y + Y C GY +A C + W
Sbjct: 224 KIIYKE----------------------NERFQYKCNMGYEYSERGDAVCTES-----GW 256
Query: 2485 DSLTPLCQAVSCGIPESPGNGSF--------TGNEFTLDSKVVYECHEGFKLESSQQATA 2536
L P C+ SC P P NG + TG+E T Y+C GF +++ TA
Sbjct: 257 RPL-PSCEEKSCDNPYIP-NGDYSPLRIKHRTGDEIT------YQCRNGF-YPATRGNTA 307
Query: 2537 VCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWR-----LVSGSLNEYGAQVLLSCSP 2591
C G W + T KP P I+ H R + G Y
Sbjct: 308 KCTSTG-WIPAPR-CTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPS 365
Query: 2592 GYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNG--NKIGTLTVYGATAIFTC 2649
G Y W + C +G W+ P+ + + NG G V G + C
Sbjct: 366 GSY---WDHIHCTQDG-WS-----PAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVAC 416
Query: 2650 NTGYTLVGSHVR-ECLANGLWSGSETRCLAGHCG-SPDPIVNGHISGDGFSY--RDTVVY 2705
+ GY L + C+ NG WS + C S I NG IS ++Y ++ Y
Sbjct: 417 HPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKY 475
Query: 2706 QCNPGFRLVG--TSVRICLQDHKWSGQTPVCVPITCGHP----GNPAHGFTNGSEFNLND 2759
QC G+ TS I WS Q P C+ +C P + FT F LND
Sbjct: 476 QCKLGYVTADGETSGSITCGKDGWSAQ-PTCIK-SCDIPVFMNARTKNDFT---WFKLND 530
Query: 2760 VVNFTCNTGYLLQGVSRA---QCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPE 2816
+++ C+ GY S C NG WS LP C C P + + ++ +
Sbjct: 531 TLDYECHDGYESNTGSTTGSIVCGYNG-WSD-LPICYERECELPKIDVHLVPDRKK---D 585
Query: 2817 SFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC--LAISCGHPGVPANAVL--- 2871
++ G + + CK GF ++G +++ C GL LP C SCG P N +
Sbjct: 586 QYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEK 644
Query: 2872 TGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHG- 2930
T E + + VV Y C + G + C D W+ LP C CGD HG
Sbjct: 645 TKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWT-TLPVCIVEE-STCGDIPELEHGW 701
Query: 2931 -SRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGM 2989
+ + F+C + G TC ++G W+ L P C A+ +N +
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWTQL-PQCVAIDKLKKCKSSNLI 759
Query: 2990 IV-----SSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIIS---CGDP 3041
I+ + +S++ Y C G + C NG W +C++ C P
Sbjct: 760 ILEEHLKNKKEFDHNSNIRYRC---RGKEGWIHTVC-INGRWDPEV-NCSMAQIQLCPPP 814
Query: 3042 GTLANGIQFGTDFTF--NKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVC-KAVLC 3098
+ N T + + VS C Y+++ T KDGRW S P+C + + C
Sbjct: 815 PQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEIT---CKDGRWQ-SIPLCVEKIPC 870
Query: 3099 PQPPPVQNGTVEGS-----DFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLP 3153
QPP +++GT+ S + G+ +SY+C G+++S +C G W PQC
Sbjct: 871 SQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWSSP-PQCEG 928
Query: 3154 VFCGDPGIPAEGRLS--GKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCID 3211
+ C P + G ++ S+ Y EV ++C F + G + C + WS P+CI
Sbjct: 929 LPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWSH-PPSCIK 986
Query: 3212 PAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3271
+ P + Y+ G V + C Y + G++ TC+ N W+G T C
Sbjct: 987 TDCLSLPSFENA-IPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCI-NSRWTGRPT-C 1043
Query: 3272 IPHACRQPETPAHADVRAIDLPTF--GYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSP 3329
+C P T +A + + + + G + Y C + + G E + WT + P
Sbjct: 1044 RDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGN--WT-EPP 1100
Query: 3330 VCK 3332
CK
Sbjct: 1101 QCK 1103
Score = 157 bits (397), Expect = 2e-37
Identities = 169/695 (24%), Positives = 261/695 (37%), Gaps = 120/695 (17%)
Query: 2676 CLAGHCGSPDP-----IVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQ 2730
C+A C P I+ G S + +Y+C PG+R +G + +C + +W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2731 TPV--CVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQG-VSRAQCRSNGQ 2784
P+ C CGHPG+ G T G+ F +TCN GY L G ++ +C ++G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 2785 WSSPLPTCRVVNCSDPGFVENA-IRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCM 2843
W++ +P C VV C EN I + +G ++ + C G+ + G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2844 ANGLWDRSLPKCLAISCGHPGVPANAVLTGE-LFTYGAVVHYSCRGSESLIGNDTRVCQE 2902
+G W + PKC+ ISC P V + ++ + ++ Y C VC E
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 2903 DSHWSGALPHCTGNNPGFCGDPGTP-AHGSRLGDDFKTKSLLRFSCEMGH--QLRGSPER 2959
S W LP C + C +P P S L +T + + C G RG+ +
Sbjct: 254 -SGWR-PLPSCEEKS---CDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK 308
Query: 2960 TCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSS-----DGILFSSSVIYACWEGYKT-S 3013
C G W P C C P G+ + + Y C E ++T S
Sbjct: 309 -CTSTG-WIP-APRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPS 365
Query: 3014 GLMTR--HCTANGTWTGTAPDCTIISCGDPGTLANGI--QFGTDFTFNKTVSYQCNPGYV 3069
G HCT +G W+ P + C P L NG G F K++ C+PGY
Sbjct: 366 GSYWDHIHCTQDG-WSPAVP--CLRKCYFP-YLENGYNQNHGRKFVQGKSIDVACHPGYA 421
Query: 3070 MEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPP-PVQNGTVEGSDFRWG--SSISYSCMD 3126
+ T+ C ++G W+P+ + C + ++NG + S + + Y C
Sbjct: 422 LPK-AQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKL 479
Query: 3127 GYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPF 3186
GY + A+G SG
Sbjct: 480 GY--------------------------------VTADGETSGSI--------------- 492
Query: 3187 ILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRK 3246
C DG WS QPTCI +C P + +N +++ T+ + C
Sbjct: 493 --------TCGKDG-WSA-QPTCI----KSCDIPVFMNARTKNDFTWFKLNDTLDYECHD 538
Query: 3247 GYHIQ-GSTTRTCLANLT-WSGIQTECIPHACRQPETPAH-ADVRAIDLPTFGYTLVYTC 3303
GY GSTT + + WS + C C P+ H R D G L ++C
Sbjct: 539 GYESNTGSTTGSIVCGYNGWSDLPI-CYERECELPKIDVHLVPDRKKDQYKVGEVLKFSC 597
Query: 3304 HPGFFLAGGSE----HRTCKADMKWTGKSPVCKSK 3334
PGF + G + H D+ P+CK +
Sbjct: 598 KPGFTIVGPNSVQCYHFGLSPDL------PICKEQ 626
Score = 140 bits (354), Expect = 2e-32
Identities = 159/612 (25%), Positives = 240/612 (39%), Gaps = 67/612 (10%)
Query: 2452 VGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLC--QAVSCGIPESPGNGSF-- 2507
VG + + CKPG+ +VG ++ C + P+C Q SCG P NG+
Sbjct: 589 VGEVLKFSCKPGFTIVGPNSVQCYH-----FGLSPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 2508 -TGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLS 2566
T E+ V Y C+ F ++ + V DG W+ P C +
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV---DGEWTTL---PVCIVEESTCGDIPEL 697
Query: 2567 EHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSL 2626
EH W +S YG V +CS + + G R + C +G W + P C ++ L
Sbjct: 698 EHG-WAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT---QLPQC--VAIDKL 750
Query: 2627 SFPPNGNKIGTLTVYGATAIFTCNTG--YTLVGSH--VRECLANGLWSGSETRCLAGH-- 2680
+ N I F N+ Y G + NG W E C
Sbjct: 751 KKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD-PEVNCSMAQIQ 809
Query: 2681 -CGSPDPIVNGHISGDGFSYRD--TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCV-P 2736
C P I N H +YRD V C + L+ I +D +W P+CV
Sbjct: 810 LCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQ-SIPLCVEK 867
Query: 2737 ITCGHPGNPAHGFTNGSEFNLNDV-----VNFTCNTGYLLQGVSRAQCRSNGQWSSPLPT 2791
I C P HG N S + +++TC G+ + + C G+WSSP P
Sbjct: 868 IPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYM-GKWSSP-PQ 925
Query: 2792 CRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRS 2851
C + C P + + + + +S++YG + Y C +GF + G + C+ W
Sbjct: 926 CEGLPCKSPPEISHGV---VAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWSHP 981
Query: 2852 LPKCLAISCGHPGVPANAVLTGE---LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSG 2908
P C+ C NA+ GE ++ G V Y+C + G C +S W+G
Sbjct: 982 -PSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWTG 1039
Query: 2909 ALPHCTGNNPGFCGDPGTPAHG---SRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNG 2965
P C + C +P T + SR + + +R+ C +++ G E C LNG
Sbjct: 1040 R-PTCRDTS---CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNG 1094
Query: 2966 SWSGLQPVCE--AVSCGNPGTPTNGMIVSSDGILF--SSSVIYACWEGYKTSGLMTRHCT 3021
+W+ P C+ CG P NG I S ++ +SSV Y C Y+ G C
Sbjct: 1095 NWTE-PPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC- 1152
Query: 3022 ANGTWTGTAPDC 3033
NG W+ P C
Sbjct: 1153 RNGQWS-EPPKC 1163
Score = 139 bits (351), Expect = 4e-32
Identities = 184/752 (24%), Positives = 300/752 (39%), Gaps = 115/752 (15%)
Query: 2458 YFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGN--GSFTGNEFTLD 2515
Y C GY ++ +T G W L P+C C +P+ + +++ +
Sbjct: 534 YECHDGYE--SNTGSTTGSIVCGYNGWSDL-PICYERECELPKIDVHLVPDRKKDQYKVG 590
Query: 2516 SKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPV--ACPSIEAQLSEHVIWRL 2573
+ + C GF + C GL + P CK +C L+ +V +
Sbjct: 591 EVLKFSCKPGFTIVGPNSVQ--CYHFGLSPDL---PICKEQVQSCGPPPELLNGNVKEK- 644
Query: 2574 VSGSLNEYGAQVLLS--CSPGYYLEGWRLLRCQANGTWNIGDERPSCRV--ISCGSLSFP 2629
+ EYG ++ C+P + ++G ++C +G W P C V +CG +
Sbjct: 645 ---TKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWTT---LPVCIVEESTCGDIPEL 697
Query: 2630 PNG--NKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLA----GHCGS 2683
+G YG + F C+ +T++G C+ +G+W+ +C+A C S
Sbjct: 698 EHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKS 755
Query: 2684 PDPIV-NGHISGDG-FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWS-------GQTPVC 2734
+ I+ H+ F + + Y+C + T +C+ +W Q +C
Sbjct: 756 SNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHT---VCING-RWDPEVNCSMAQIQLC 811
Query: 2735 VPITCGHPGNP-AHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC- 2792
P P P +H T + + V+ C YL+Q C+ +G+W S +P C
Sbjct: 812 PP----PPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQS-IPLCV 865
Query: 2793 RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSL 2852
+ CS P +E+ + ++ ES+ +G + Y C+ GF + + TC G W S
Sbjct: 866 EKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYM-GKWS-SP 923
Query: 2853 PKCLAISCGHPGVPANAVLT--GELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGAL 2910
P+C + C P ++ V+ + + YG V Y C + G C + WS
Sbjct: 924 PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK-WSHP- 981
Query: 2911 PHCTGNN----PGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGS 2966
P C + P F + P + D +K + ++C +++ G+ TC +N
Sbjct: 982 PSCIKTDCLSLPSF--ENAIPMGEKK--DVYKAGEQVTYTCATYYKMDGASNVTC-INSR 1036
Query: 2967 WSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSS--VIYACWEGYKTSGLMTRHCTANG 3024
W+G +P C SC NP T N IVS + S V Y C Y+ G C NG
Sbjct: 1037 WTG-RPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNG 1094
Query: 3025 TWTGTAPDC--TIISCGDPGTLANGIQFGTDFTFN-----KTVSYQCNPGYVMEAVTSAT 3077
WT P C + CG P + NG T F + +V YQC Y +E T
Sbjct: 1095 NWT-EPPQCKDSTGKCGPPPPIDNGDI--TSFPLSVYAPASSVEYQCQNLYQLEGNKRIT 1151
Query: 3078 IRCTKDGRWN-PSKPVCKAVLCPQPPPVQNGTVEGSD--FRW----------GSSISYSC 3124
R +G+W+ P K C P + +E + RW G S+ + C
Sbjct: 1152 CR---NGQWSEPPK-------CLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVC 1201
Query: 3125 MDGYQL---SHSAILSCEGRGVWKG--EIPQC 3151
GY+L SH+ +C W G E P C
Sbjct: 1202 KRGYRLSSRSHTLRTTC-----WDGKLEYPTC 1228
Score = 118 bits (296), Expect = 9e-26
Identities = 253/1242 (20%), Positives = 427/1242 (34%), Gaps = 273/1242 (21%)
Query: 1755 GSEFSAGSIVRFECNPGYLLQGS-TALHCQSVPNALAQWNDTIPSC-VVPCSGNFTQRRG 1812
G+ F G + CN GY L G C + W + IP C VV C G
Sbjct: 101 GNVFEYGVKAVYTCNEGYQLLGEINYRECDT-----DGWTNDIPICEVVKCLPVTAPENG 155
Query: 1813 TILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGS 1872
I+S + + + G I+ ++ + S E P+
Sbjct: 156 KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKE--------KPKCVE 207
Query: 1873 FSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPA---LPSNSIKIG 1929
S + + S +Q ++ +++ EY G A C E LPS K
Sbjct: 208 ISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEKSC 267
Query: 1930 D--------------RYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IAT 1974
D ++ D +++QC G+ R + + T W P+P C +
Sbjct: 268 DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST--GW-IPAPRCTLKP 324
Query: 1975 CGGTLSTLGGV----ILSPGFP-------------------GSYPNNLDCT---WRISLP 2008
C GG+ + P FP GSY +++ CT W ++P
Sbjct: 325 CDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVP 384
Query: 2009 IGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSD 2068
+ +L NH +Q S + G LP A + T
Sbjct: 385 CLRKCYFPYLENGYNQNHGRKFVQG----KSIDVACHPGYALPKAQTTVT---------- 430
Query: 2069 HSQNRQGFKLAYQAYELQNCPDPP-PFQNGYMINSD--YSVGQSVSFECYPGYILIGHPV 2125
G+ + ++ C +NG++ S Y++ + ++C GY+
Sbjct: 431 --CMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGET 488
Query: 2126 ---LTCQHGINRNWNYP---FPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITV 2179
+TC W+ CD P N ++N
Sbjct: 489 SGSITCG---KDGWSAQPTCIKSCDIPVFMNARTKN------------------------ 521
Query: 2180 PPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHS 2239
+FT + DY DG + N+ S ++ Y+ + + + +
Sbjct: 522 --------DFTWFKLNDTLDY-ECHDGYESNTG-----STTGSIVCGYNGWSDLPICYE- 566
Query: 2240 DFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDIL 2299
++C+ P + D +++G+ +K+ C PG+T+VG + +
Sbjct: 567 -----------------RECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSV 609
Query: 2300 TCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYN 2359
C LP C+ Q + S G P N K + Y
Sbjct: 610 QC---YHFGLSPDLPICKEQ-------------VQSCGPPPELLNGNV---KEKTKEEYG 650
Query: 2360 ITIFVDTFQSE----KQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWST 2415
+ V+ + + K + ++ DG P+ +V E+S
Sbjct: 651 HSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIV------EEST------------CG 692
Query: 2416 DHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCR 2475
D + G+ + PY G V + C + M+GH + TC
Sbjct: 693 DIPELEHGWAQLSSPPY------------------YYGDSVEFNCSESFTMIGHRSITCI 734
Query: 2476 RNPLGMYQWDSLTPLCQAVSCGIPESPGNGSF-------TGNEFTLDSKVVYECH--EGF 2526
W L P C A+ + + + EF +S + Y C EG+
Sbjct: 735 HG-----VWTQL-PQCVAID-KLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGW 787
Query: 2527 KLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN-EYGAQV 2585
VC +G W + + CP + H ++ +LN G +V
Sbjct: 788 -------IHTVC-INGRWDPEVNCSMAQIQLCPPPPQIPNSH----NMTTTLNYRDGEKV 835
Query: 2586 LLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC-RVISCGSLSFPPNGNKIGTLT----- 2639
+ C Y ++ + C+ +G W P C I C S PP + GT+
Sbjct: 836 SVLCQENYLIQEGEEITCK-DGRW---QSIPLCVEKIPC---SQPPQ-IEHGTINSSRSS 887
Query: 2640 ----VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHIS-- 2693
+G +TC G+ + + C G WS S +C C SP I +G ++
Sbjct: 888 QESYAHGTKLSYTCEGGFRISEENETTCYM-GKWS-SPPQCEGLPCKSPPEISHGVVAHM 945
Query: 2694 GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGS 2753
D + Y + V Y+C GF + G ++ CL + KWS P C+ C + + G
Sbjct: 946 SDSYQYGEEVTYKCFEGFGIDGPAIAKCLGE-KWS-HPPSCIKTDCLSLPSFENAIPMGE 1003
Query: 2754 E---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHG 2810
+ + + V +TC T Y + G S C N +W+ PTCR +C +P V+NA
Sbjct: 1004 KKDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWTG-RPTCRDTSCVNPPTVQNAYIVS 1061
Query: 2811 QQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAIS--CGHPGVPAN 2868
+Q + G + Y C+ + + G + C+ NG W P+C + CG P N
Sbjct: 1062 RQ--MSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWTEP-PQCKDSTGKCGPPPPIDN 1117
Query: 2869 AVLTG---ELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWS 2907
+T ++ + V Y C+ L GN C+ + WS
Sbjct: 1118 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS 1158
Score = 97.1 bits (240), Expect = 3e-19
Identities = 100/381 (26%), Positives = 160/381 (41%), Gaps = 51/381 (13%)
Query: 2435 LTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV 2494
+ H N ++ + A G+K+ Y C+ G+R+ + TC M +W S P C+ +
Sbjct: 876 IEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY-----MGKWSS-PPQCEGL 929
Query: 2495 SCGIPESPGNG--SFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
C P +G + + + +V Y+C EGF ++ A + ++ WS+ PP+
Sbjct: 930 PCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK---WSH---PPS 983
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
C C S+ + E+ I + + G QV +C+ Y ++G + C N W
Sbjct: 984 CIKTDCLSLPS--FENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWT-- 1038
Query: 2613 DERPSCRVISCGSLSFPPNGNKIG-TLTVY--GATAIFTCNTGYTLVGSHVRECLANGLW 2669
RP+CR SC + N + ++ Y G + C + Y + G CL NG W
Sbjct: 1039 -GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNW 1096
Query: 2670 S-GSETRCLAGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNPGFRLVGTSVRICLQDH 2725
+ + + G CG P PI NG I+ ++ +V YQC ++L G RI ++
Sbjct: 1097 TEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNK-RITCRNG 1155
Query: 2726 KWSGQTPVCVPITCGHP----------GNPAHGFTNGSEF--NLNDVVNFTCNTGYLLQG 2773
+WS P C HP N A +T + + V F C GY L
Sbjct: 1156 QWS------EPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLS- 1208
Query: 2774 VSRAQCRSNGQWSSPL--PTC 2792
SR+ W L PTC
Sbjct: 1209 -SRSHTLRTTCWDGKLEYPTC 1228
Score = 75.9 bits (185), Expect = 7e-13
Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 15/229 (6%)
Query: 3092 VCKAVLCPQPPPVQN-----GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKG 3146
+C A C + PP +N G+ + G+ Y C GY+ + I+ C +G W
Sbjct: 15 ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVA 73
Query: 3147 EIP--QCLPVFCGDPGIPAEGRLS---GKSFTYKSEVFFQCKSPFILVGS-SRRVCQADG 3200
P +C CG PG G + G F Y + + C + L+G + R C DG
Sbjct: 74 LNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG 133
Query: 3201 TWSGIQPTC--IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC 3258
W+ P C + T P+ G R Y G V F C GY I+G C
Sbjct: 134 -WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC 192
Query: 3259 LANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGF 3307
+ WS + +C+ +C+ P+ + + + Y C+ G+
Sbjct: 193 SDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGY 241
Score = 75.9 bits (185), Expect = 7e-13
Identities = 133/645 (20%), Positives = 225/645 (34%), Gaps = 106/645 (16%)
Query: 2084 ELQNCPDPPPFQNGYM---INSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPF 2140
++Q+C PP NG + +Y + V + C P +++ G + C G W
Sbjct: 626 QVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDG---EWT-TL 681
Query: 2141 PRC---DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYIN----FTLLQ 2193
P C ++ CG ++G P Y G V N FT++
Sbjct: 682 PVCIVEESTCGDIPELEHGWAQLSSPPYYY--------------GDSVEFNCSESFTMIG 727
Query: 2194 TEAVNDYIAVWDGPDQ----------NSPQLGVFSGNTALETAYSSTNQVLLK------- 2236
++ VW Q S L + + + + + + +
Sbjct: 728 HRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGW 787
Query: 2237 FHSDFSNGGFFV-LNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVG 2295
H+ NG + +N Q++ C PPP +P + +T ++ G+ V C Y +
Sbjct: 788 IHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQE 847
Query: 2296 TDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILS-----PGYPGNYFNSQTCSW 2350
+ +TCK + Q S+P C + P ++ G I S Y S TC
Sbjct: 848 GEEITCK-DGRWQ---SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEG 903
Query: 2351 SIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLY 2410
++ T ++ + S Q + L ++ +S ++ T + +
Sbjct: 904 GFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYK---CF 960
Query: 2411 LRWSTDHATSKKGFKIRYA-APYCSLTHPLKNGGILN-------RTAGAVGSKVHYFCKP 2462
+ D K +++ P C T L N + G +V Y C
Sbjct: 961 EGFGIDGPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCAT 1020
Query: 2463 GYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTG---NEFTLDSKVV 2519
Y+M G SN TC + +W P C+ SC P + N +++ +V
Sbjct: 1021 YYKMDGASNVTCINS-----RWTG-RPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVR 1074
Query: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVA--C----PSIEAQLSEHVIWRL 2573
Y+C +++ ++ + +G W+ +PP CK C P ++ +
Sbjct: 1075 YQCRSPYEMFGDEEVMCL---NGNWT---EPPQCKDSTGKCGPPPPIDNGDITSFPLSVY 1128
Query: 2574 VSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGN 2633
S EY Q L Y LEG + + C+ NG W+ E P C S N N
Sbjct: 1129 APASSVEYQCQNL------YQLEGNKRITCR-NGQWS---EPPKCLHPCVISREIMENYN 1178
Query: 2634 -------KIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSG 2671
K + G + F C GY L S L W G
Sbjct: 1179 IALRWTAKQKLYSRTGESVEFVCKRGYRL--SSRSHTLRTTCWDG 1221
Score = 62.8 bits (151), Expect = 6e-09
Identities = 175/935 (18%), Positives = 298/935 (31%), Gaps = 229/935 (24%)
Query: 1747 EPRYGRRIGSEFSAGSIVRFECNPGYLL-QGSTALHCQSVPNALAQWNDTIPSC--VVPC 1803
E Y + G +F G + C+PGY L + T + C W+ T P C V C
Sbjct: 395 ENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCME-----NGWSPT-PRCIRVKTC 448
Query: 1804 SGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHDGG 1863
S + +S + + E + Q + + + T S I G
Sbjct: 449 SKSSIDIENGFISESQ-----------YTYALKEKAKYQCK-LGYVTADGETSGSITCGK 496
Query: 1864 DVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYK-----TVGLAAC-- 1916
D + + +P +N+ + + F+ + ++ H Y+ T G C
Sbjct: 497 DGWSAQPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYE-CHDGYESNTGSTTGSIVCGY 555
Query: 1917 -----------QEPALPSNSIKI-----GDRYMVNDVLSFQCEPGYTLQGRSHISCMPGT 1960
+E LP + + D+Y V +VL F C+PG+T+ G + + C
Sbjct: 556 NGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG 615
Query: 1961 VRRWNYPSPLC---IATCGGTLSTLGGVI-----------------LSPGFPGSYPNNLD 2000
+ + P+C + +CG L G + +P F PN +
Sbjct: 616 L---SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQ 672
Query: 2001 CT---WRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYH-----------TSPMIGQFS 2046
C W +LP+ E H + ++ + PY+ + MIG S
Sbjct: 673 CVDGEW-TTLPVCI-VEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRS 730
Query: 2047 -------GTDLPAAL----LSTTHETLIHFYSDHSQNRQGF----KLAYQA--------- 2082
T LP + L + + +H +N++ F + Y+
Sbjct: 731 ITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHT 790
Query: 2083 ---------------YELQNCPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIGHPV 2125
++Q CP PP N + + + +Y G+ VS C Y++
Sbjct: 791 VCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE 850
Query: 2126 LTCQHGINRNWNYPFPRC--DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGH 2183
+TC+ G W P C PC ++GTI S E H
Sbjct: 851 ITCKDG---RWQ-SIPLCVEKIPCSQPPQIEHGTINSSRSSQE-------------SYAH 893
Query: 2184 GVYINFT------LLQTEAVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKF 2237
G +++T + + Y+ W P Q
Sbjct: 894 GTKLSYTCEGGFRISEENETTCYMGKWSSPPQ---------------------------- 925
Query: 2238 HSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTD 2297
+ C+ PP + + D ++ G+ V Y+C G+ + G
Sbjct: 926 ----------------CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPA 969
Query: 2298 ILTCKLSSQLQFEGSLPTCEAQCPA--NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVE 2355
I C + T P+ N + G + G Y TC+ K++
Sbjct: 970 IAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTY----TCATYYKMD 1025
Query: 2356 PNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLS-GNHTEQSNFTSRSNQLYLRWS 2414
N+T + + + Q+ +V + + Y +
Sbjct: 1026 GASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFG 1085
Query: 2415 TDHATSKKGF-----KIRYAAPYCSLTHPLKNGGILN--RTAGAVGSKVHYFCKPGYRMV 2467
+ G + + + C P+ NG I + + A S V Y C+ Y++
Sbjct: 1086 DEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLE 1145
Query: 2468 GHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSK--------VV 2519
G+ TCR QW S P C C I +T K V
Sbjct: 1146 GNKRITCRNG-----QW-SEPPKC-LHPCVISREIMENYNIALRWTAKQKLYSRTGESVE 1198
Query: 2520 YECHEGFKLES-SQQATAVCQEDGLWSNKGKPPTC 2553
+ C G++L S S C W K + PTC
Sbjct: 1199 FVCKRGYRLSSRSHTLRTTC-----WDGKLEYPTC 1228
Score = 45.1 bits (105), Expect = 0.001
Identities = 61/270 (22%), Positives = 113/270 (41%), Gaps = 35/270 (12%)
Query: 523 IEKGGCGDPGIP----AYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNK 578
+E+ CGD IP + + + + +GD++ F C +F ++G R ITC + W+
Sbjct: 686 VEESTCGD--IPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT-QL 741
Query: 579 PSCVFSCFFNFTASSGIILSPNY---PEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ 635
P CV SS +I+ + +E+ +N N + + G IH + + +P+
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEG-WIHTVCINGRWDPE 800
Query: 636 FDFLAVKDD---------GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGF 686
+ + ++T + E S L ++++ E + GR
Sbjct: 801 VNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQ-EGEEITCKDGRWQ 859
Query: 687 NITYTTFGQNECHDP-----GIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCIL 741
+I + C P G + R + + G+ +S+ C+ GF ++ +E+ TC +
Sbjct: 860 SIPLCV-EKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENET-TCYM 917
Query: 742 QDGNVVWSSTVPRCEA-PCGGHLTASSGVI 770
WSS P+CE PC S GV+
Sbjct: 918 GK----WSSP-PQCEGLPCKSPPEISHGVV 942
Score = 42.7 bits (99), Expect = 0.006
Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 44/249 (17%)
Query: 1054 FSRRIGFHFGVGDSLTFSCFLGYRLEGA-TKLTCLGGGRRVWSAPLPRC--VAECGASVK 1110
+++ G F G S+ +C GY L A T +TC+ G WS P PRC V C S
Sbjct: 398 YNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG---WS-PTPRCIRVKTCSKS-- 451
Query: 1111 GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTL-KVYDGKDS-SS 1168
S + + + + + Y ++ +A L + +G+T + GKD S+
Sbjct: 452 -------SIDIENGFISESQYTYALKEKAKYQCKL---GYVTADGETSGSITCGKDGWSA 501
Query: 1169 RP-----------LGTFTKNELLGLILNSTSNHLWLE-FNTNGSDTDQGFQLTYTSFDLV 1216
+P + TKN+ LN T ++ + + +N T Y + +
Sbjct: 502 QPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDL 561
Query: 1217 ------KCEDPGIPNYGYRIRDEGHF-TDTVVLYSCNPGYAMHGSNTLTC----LSGDRR 1265
+CE P I + R + + V+ +SC PG+ + G N++ C LS D
Sbjct: 562 PICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLP 621
Query: 1266 VWDKPLPSC 1274
+ + + SC
Sbjct: 622 ICKEQVQSC 630
Score = 41.6 bits (96), Expect = 0.014
Identities = 61/253 (24%), Positives = 93/253 (36%), Gaps = 34/253 (13%)
Query: 1392 CNDPGMPQNGT--RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI 1449
C P +G DS + G+ VT++C G+ + G A C+ W PP+CI
Sbjct: 931 CKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK----WS-HPPSCI 985
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKE----CDWRVKVNPDFVIALIFKSFNMEPSYDF 1505
+L I Y G++ C K++ + I + P+
Sbjct: 986 KTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRD 1045
Query: 1506 LHIYEGEDSNSPLIGSYQGSQAP--ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR- 1562
+ I S Q S+ P ER+ S + F + + L+G + E P+
Sbjct: 1046 TSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNG---NWTEPPQC 1102
Query: 1563 ----EACFDPGNIMNGTRVGTDFKLG-----STITYQCDSGYKILDPSSITCVIGADGKP 1613
C P I NG T F L S++ YQC + Y++ ITC G +P
Sbjct: 1103 KDSTGKCGPPPPIDNGDI--TSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEP 1160
Query: 1614 SWDQVLPSCNAPC 1626
P C PC
Sbjct: 1161 ------PKCLHPC 1167
Score = 40.4 bits (93), Expect = 0.032
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 10/73 (13%)
Query: 1734 VPRTSDTQCSSVPEPRYGRRIGS------EFSAGSIVRFECNPGYLLQGSTALHCQSVPN 1787
+P +C V P G+ + S E+ G VRF CN GY ++G +HC
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDD-- 195
Query: 1788 ALAQWNDTIPSCV 1800
W+ P CV
Sbjct: 196 --GFWSKEKPKCV 206
Score = 36.2 bits (82), Expect = 0.60
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 2086 QNCPDPPPFQN-----GYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPF 2140
++C + PP +N G + Y G ++C PGY +G+ ++ C+ G N P
Sbjct: 19 EDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PL 77
Query: 2141 PRCD-APCGYNVTSQNGTIYSPG 2162
+C PCG+ + GT G
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTG 100
Score = 35.8 bits (81), Expect = 0.78
Identities = 41/178 (23%), Positives = 69/178 (38%), Gaps = 29/178 (16%)
Query: 948 PDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEP--VARLTGSVL 1005
P PNS N T T+ G+ V ++ +L + + + S P V ++ S
Sbjct: 814 PPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 1006 PHTIKAGLFGNFTAQLRFISDFSISYE---GFNITFS--------------EYDLEPCDD 1048
P + + ++Q + +SY GF I+ + + PC
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKS 933
Query: 1049 PGVPAFSRRIGFH----FGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
P P S + H + G+ +T+ CF G+ ++G CLG WS P P C+
Sbjct: 934 P--PEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLG---EKWSHP-PSCI 985
Score = 35.0 bits (79), Expect = 1.3
Identities = 137/679 (20%), Positives = 219/679 (32%), Gaps = 172/679 (25%)
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVV--LYSCNPGYAMHGS-NTLTCLSGDRRVWDKPLPSC 1274
C PG +G G+ + V +Y+CN GY + G N C D W +P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYREC---DTDGWTNDIPIC 141
Query: 1275 IAECGGQIHAATSGRILSP--------------------GYPAPYDNNLHCT----WIIE 1310
+ A +G+I+S GY D +HC+ W E
Sbjct: 142 EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKE 201
Query: 1311 ADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFD 1370
IS + D++ P+ I+ KE ++ ++
Sbjct: 202 KPKCVEISCK--------SPDVIN--GSPISQKIIYKENERFQYKCNMGYEYSER----- 246
Query: 1371 SDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSR---EAGDTVTFQCDPGYQLQGQ 1427
D ++SG+ + +C++P +P NG Y R GD +T+QC G+ +
Sbjct: 247 GDAVCTESGWR-PLPSCEEKSCDNPYIP-NGD-YSPLRIKHRTGDEITYQCRNGFYPATR 303
Query: 1428 AKIT-CVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNP 1486
C W P P + C G + N +PY P V V
Sbjct: 304 GNTAKCTSTG----WIPAPRCTLKPCDYPDIKHGG-LYHENMRRPYFP-------VAVGK 351
Query: 1487 DFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDA 1546
+ + F + HI+ +D SP + + P + F
Sbjct: 352 -YYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGK 410
Query: 1547 SVGLS---GFAIEFKEKPREACFDPG------------------NIMNG--TRVGTDFKL 1583
S+ ++ G+A+ K + C + G +I NG + + L
Sbjct: 411 SIDVACHPGYALP-KAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYAL 469
Query: 1584 GSTITYQCDSGYKILD---PSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVLSP 1640
YQC GY D SITC GK W P+C C
Sbjct: 470 KEKAKYQCKLGYVTADGETSGSITC-----GKDGWS-AQPTCIKSC-------------- 509
Query: 1641 NYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLA--ELFDG--THAQARLLSSLS 1696
I V F +F+ LND E DG ++ + S +
Sbjct: 510 --------------DIPVFMNARTKNDFTWFK--LNDTLDYECHDGYESNTGSTTGSIVC 553
Query: 1697 GSHSGETLPLATSNQI----------------------LLRFSAKSGASARG------FH 1728
G + LP+ + +L+FS K G + G +H
Sbjct: 554 GYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYH 613
Query: 1729 FVYQA---VPRTSDTQCSSVPEPRYGR---RIGSEFSAGSIVRFECNPGYLLQGSTALHC 1782
F + + C PE G + E+ +V + CNP +L++G + C
Sbjct: 614 FGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC 673
Query: 1783 QSVPNALAQWNDTIPSCVV 1801
+W T+P C+V
Sbjct: 674 VD-----GEWT-TLPVCIV 686
Score = 34.7 bits (78), Expect = 1.7
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 12/88 (13%)
Query: 1565 CFDPGNIMNGTRVGT-----DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVL 1619
C P I +GT + + G+ ++Y C+ G++I + + TC +G P
Sbjct: 870 CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSP------ 923
Query: 1620 PSCNA-PCGGQYTGSEGVVLSPNYPHNY 1646
P C PC S GVV + + Y
Sbjct: 924 PQCEGLPCKSPPEISHGVVAHMSDSYQY 951
Score = 33.9 bits (76), Expect = 3.0
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 1194 EFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRD------EGHFTDTVVLYSCNP 1247
E N DTD G+ ++VKC P G + E HF V + CN
Sbjct: 123 EINYRECDTD-GWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAV-RFVCNS 180
Query: 1248 GYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
GY + G + C D W K P C+
Sbjct: 181 GYKIEGDEEMHC--SDDGFWSKEKPKCV 206
Score = 33.9 bits (76), Expect = 3.0
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 7/43 (16%)
Query: 1240 VVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAE---CG 1279
VV Y CNP + M G N + C+ G+ W LP CI E CG
Sbjct: 654 VVEYYCNPRFLMKGPNKIQCVDGE---W-TTLPVCIVEESTCG 692
Score = 33.5 bits (75), Expect = 3.9
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 1060 FHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
+HFG ++ F C GY++EG ++ C G WS P+CV
Sbjct: 168 YHFG--QAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 33.5 bits (75), Expect = 3.9
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 526 GGCGDPGIPAYGKRTG---SSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV 582
G CG P G T S + ++ ++C ++L G + ITC +N QWS P C+
Sbjct: 1107 GKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCL 1164
Query: 583 FSC 585
C
Sbjct: 1165 HPC 1167
Score = 32.7 bits (73), Expect = 6.6
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 521 QEIEKGGCGDPGIPAYGKRT---GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGN 577
++ +K CG PG +G T G+ F +G + C ++L+GE + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 578 KPSC-VFSCFFNFTASSGIILS 598
P C V C +G I+S
Sbjct: 138 IPICEVVKCLPVTAPENGKIVS 159
Score = 32.7 bits (73), Expect = 6.6
Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 547 GDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV-FSC 585
G + F C + +++ G+ + C + WS KP CV SC
Sbjct: 171 GQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISC 210
Score = 32.7 bits (73), Expect = 6.6
Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 1045 PCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAE 1104
P D+ + +F + + S+ + C Y+LEG ++TC G WS P P+C+
Sbjct: 1114 PIDNGDITSFPLSV---YAPASSVEYQCQNLYQLEGNKRITCRNG---QWSEP-PKCLHP 1166
Query: 1105 CGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQL 1152
C S + E ++ + + +E +G L +RS L
Sbjct: 1167 CVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTL 1214
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 179 bits (453), Expect = 6e-44
Identities = 116/393 (29%), Positives = 175/393 (44%), Gaps = 24/393 (6%)
Query: 2960 TCLLNGSWSGLQPVCEA-VSCGNPGTPTNGMIVSSDGI---LFSSSVIYACWEGYKTSGL 3015
TC + +SGL+ CE V+C +P +G +V S + ++SS +C GY S +
Sbjct: 162 TCKCDPGFSGLK--CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSM 219
Query: 3016 MTRHCTANGTWTGTAPDCTIISCGDPGTLANGI----QFGTDFTFNKTVSYQCNPGYVME 3071
T C ++G W+ P C ++ C ANG Q F +N T ++ C G+ E
Sbjct: 220 ETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGF--E 277
Query: 3072 AVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGS-----DFRWGSSISYSCMD 3126
+ + +++CT G W+ KP CKAV C QNG+V S +F + SS +++C +
Sbjct: 278 LMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEE 337
Query: 3127 GYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLS-----GKSFTYKSEVFFQ 3181
G+ L A + C +G W +IP C C P G ++ SF Y S F
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRG-YEVGSTV 3240
C+ F+L GS R C G W +PTC + P +S G + S+
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSC 457
Query: 3241 FFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLV 3300
F C +G+ + GST C + W+ C C P ++ P FG
Sbjct: 458 AFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCK 517
Query: 3301 YTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKS 3333
+ C G+ L GS RTC A W+G P C++
Sbjct: 518 FACPEGWTL-NGSAARTCGATGHWSGLLPTCEA 549
Score = 172 bits (437), Expect = 4e-42
Identities = 122/448 (27%), Positives = 171/448 (38%), Gaps = 44/448 (9%)
Query: 2607 GTWNIGDERPS------CRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHV 2660
G WN DER S C +C + S +G + T+ Y C+ G++
Sbjct: 123 GMWN--DERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCK----CDPGFS------ 170
Query: 2661 RECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRI 2720
GL C A +V H G+ FSY + C+ G+
Sbjct: 171 ------GLKCEQIVNCTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGYLPSSMETMQ 223
Query: 2721 CLQDHKWSGQTPVCVPITCGHPGNPAHGFT----NGSEFNLNDVVNFTCNTGYLLQGVSR 2776
C+ +WS P C + C NPA+GF N F N F C G+ L G
Sbjct: 224 CMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQS 283
Query: 2777 AQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLG 2836
QC S+G W + PTC+ V C +N + F + S + C++GF L G
Sbjct: 284 LQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQG 343
Query: 2837 SSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT-----GELFTYGAVVHYSCRGSES 2891
+ + C G W + +P C A C P + F YG+ +SC
Sbjct: 344 PAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFV 403
Query: 2892 LIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHG------SRLGDDFKTKSLLRF 2945
L G+ C W P C C P G S +G+ F KS F
Sbjct: 404 LKGSKRLQCGPTGEWDNEKPTCEAVR---CDAVHQPPKGLVRCAHSPIGE-FTYKSSCAF 459
Query: 2946 SCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYA 3005
SCE G +L GS + C G W+ P C+ V C + P + S +F + +A
Sbjct: 460 SCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFA 519
Query: 3006 CWEGYKTSGLMTRHCTANGTWTGTAPDC 3033
C EG+ +G R C A G W+G P C
Sbjct: 520 CPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 166 bits (419), Expect = 5e-40
Identities = 105/362 (29%), Positives = 154/362 (42%), Gaps = 24/362 (6%)
Query: 2876 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS---- 2931
F+Y + SC +T C WS +P C N C PA+G
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC---NVVECDAVTNPANGFVECF 256
Query: 2932 RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIV 2991
+ F + F CE G +L G+ C +G+W +P C+AV+C P NG +
Sbjct: 257 QNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVR 316
Query: 2992 SSDG----ILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAP-----DCTIISCGDPG 3042
S F SS + C EG+ G CT G WT P CT +S + G
Sbjct: 317 CSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERG 376
Query: 3043 TLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCP--- 3099
+ F + + + C G+V++ S ++C G W+ KP C+AV C
Sbjct: 377 YMNCLPSASGSFRYGSSCEFSCEQGFVLKG--SKRLQCGPTGEWDNEKPTCEAVRCDAVH 434
Query: 3100 QPPP--VQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCG 3157
QPP V+ +F + SS ++SC +G++L S L C +G W E+P C V C
Sbjct: 435 QPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCS 494
Query: 3158 DPGIPAEGRLS-GKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNT 3216
+P + +S + + F C + L GS+ R C A G WSG+ PTC P +
Sbjct: 495 SLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 3217 CP 3218
P
Sbjct: 555 IP 556
Score = 154 bits (389), Expect = 2e-36
Identities = 113/390 (28%), Positives = 169/390 (43%), Gaps = 40/390 (10%)
Query: 2492 QAVSCGIPESPGNGSFT-----GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSN 2546
Q V+C ESP +GS GN F+ +S C G+ L SS + T C G WS
Sbjct: 176 QIVNCTALESPEHGSLVCSHPLGN-FSYNSSCSISCDRGY-LPSSME-TMQCMSSGEWS- 231
Query: 2547 KGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQAN 2606
P C V C ++ + V GS + C G+ L G + L+C ++
Sbjct: 232 -APIPACNVVECDAVTNPANGFVECFQNPGSF-PWNTTCTFDCEEGFELMGAQSLQCTSS 289
Query: 2607 GTWNIGDERPSCRVISCGSLSFPPNGN------KIGTLTVYGATAIFTCNTGYTLVGSHV 2660
G W+ +E+P+C+ ++C ++ P NG+ G T + ++ FTC G+ L G
Sbjct: 290 GNWD--NEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFT-FKSSCNFTCEEGFMLQGPAQ 346
Query: 2661 RECLANGLWSGSETRCLAGHCGSPDPIVNGHIS-----GDGFSYRDTVVYQCNPGFRLVG 2715
EC G W+ C A C + G+++ F Y + + C GF L G
Sbjct: 347 VECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKG 406
Query: 2716 TSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGS-----EFNLNDVVNFTCNTGYL 2770
+ C +W + P C + C P G + EF F+C G+
Sbjct: 407 SKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFE 466
Query: 2771 LQGVSRAQCRSNGQWSSPLPTCRVVNCSD---PGFVENAIRHGQQNFPESFEYGMSILYH 2827
L G ++ +C S GQW+ +P+C+VV CS PG + N G+ F G +
Sbjct: 467 LHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKI-NMSCSGEPVF------GTVCKFA 519
Query: 2828 CKKGFYLLGSSALTCMANGLWDRSLPKCLA 2857
C +G+ L GS+A TC A G W LP C A
Sbjct: 520 CPEGWTLNGSAARTCGATGHWSGLLPTCEA 549
Score = 108 bits (271), Expect = 7e-23
Identities = 111/436 (25%), Positives = 161/436 (36%), Gaps = 80/436 (18%)
Query: 2276 DFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA-QCPANEVRTGSSGVIL 2334
+F C GY + + C S + + +P C +C A V ++G +
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGE--WSAPIPACNVVECDA--VTNPANGFVE 254
Query: 2335 SPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSG 2394
PG++ + TC TF E+ F+ + G L SG
Sbjct: 255 CFQNPGSFPWNTTC-----------------TFDCEEGFELM-------GAQSLQCTSSG 290
Query: 2395 NHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGIL--NRTAG-- 2450
N W + T K A C +NG + + AG
Sbjct: 291 N-----------------WDNEKPTCK--------AVTCRAVRQPQNGSVRCSHSPAGEF 325
Query: 2451 AVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFT-- 2508
S ++ C+ G+ + G + C QW P+C+A C +P G
Sbjct: 326 TFKSSCNFTCEEGFMLQGPAQVECTTQG----QWTQQIPVCEAFQCTALSNPERGYMNCL 381
Query: 2509 ---GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQL 2565
F S + C +GF L+ S++ C G W N+ PTC+ V C ++
Sbjct: 382 PSASGSFRYGSSCEFSCEQGFVLKGSKRLQ--CGPTGEWDNE--KPTCEAVRCDAVHQPP 437
Query: 2566 SEHVIWRLVSGSLNE--YGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISC 2623
V R + E Y + SC G+ L G L C + G W +E PSC+V+ C
Sbjct: 438 KGLV--RCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWT--EEVPSCQVVKC 493
Query: 2624 GSLSFPPNGN-KIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCG 2682
SL+ P N V+G F C G+TL GS R C A G WSG C A
Sbjct: 494 SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEA-PTE 552
Query: 2683 SPDPIVNGHISGDGFS 2698
S P+V G +S G S
Sbjct: 553 SNIPLVAG-LSAAGLS 567
Score = 54.3 bits (129), Expect = 2e-06
Identities = 84/430 (19%), Positives = 133/430 (30%), Gaps = 91/430 (21%)
Query: 161 FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSIS 220
F+ SC GY+ + C+ S W P P C C + +
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSS----GEWSAPIPACNVV-ECDAVTNPANGFVE 254
Query: 221 SPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLP 280
P + N CT F EEG++ + + S P
Sbjct: 255 CFQNPGSFPWNTTCT-----------------FDCEEGFELMGAQSLQCTSSGNWDNEKP 297
Query: 281 SPVISSKNWLRLHFTSD--SNHRRKGFNAQFQVKKAIELKSRGVKML--PSKDGSHKNSV 336
+ + +R +H G +F K + ML P++
Sbjct: 298 TCKAVTCRAVRQPQNGSVRCSHSPAG---EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQ 354
Query: 337 LSQGGVALVSDMCPDPGIPENGRR----AGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
+Q + C PE G + S R G++ +FSCE +VL+GSK + C
Sbjct: 355 WTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGP 414
Query: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPV-QYEDNAHCVWVITTTDPDKVI 451
E W + +P C A C + + P G++ + P+ ++ + C
Sbjct: 415 TGE----WDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCA------------ 458
Query: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
F E G++ L GS+ + S W +
Sbjct: 459 ------FSCEEGFE-------------------LHGST---QLECTSQGQWTEEVPSCQV 490
Query: 512 GSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQN 571
AV +I G+P + G F CP + L G TC
Sbjct: 491 VKCSSLAVPGKINMSCSGEP-------------VFGTVCKFACPEGWTLNGSAARTCGAT 537
Query: 572 NQWSGNKPSC 581
WSG P+C
Sbjct: 538 GHWSGLLPTC 547
Score = 53.5 bits (127), Expect = 4e-06
Identities = 63/248 (25%), Positives = 91/248 (36%), Gaps = 39/248 (15%)
Query: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA-PCGGQYTGSEGVVLS 1639
F +T T+ C+ G++++ S+ C + WD P+C A C G V
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVRQPQNGSVRC 317
Query: 1640 PNYPH---------NYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGT----- 1685
+ P N+T + + E GQ+ T + E F T
Sbjct: 318 SHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQW----TQQIPVCEAFQCTALSNP 373
Query: 1686 -HAQARLLSSLSGSHS-GETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCS 1743
L S SGS G + + +L+ S + G P +C
Sbjct: 374 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWD--NEKPTCEAVRCD 431
Query: 1744 SVPEPRYG------RRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
+V +P G IG EF+ S F C G+ L GST L C S QW + +P
Sbjct: 432 AVHQPPKGLVRCAHSPIG-EFTYKSSCAFSCEEGFELHGSTQLECTS----QGQWTEEVP 486
Query: 1798 SC-VVPCS 1804
SC VV CS
Sbjct: 487 SCQVVKCS 494
Score = 50.8 bits (120), Expect = 2e-05
Identities = 90/419 (21%), Positives = 137/419 (32%), Gaps = 97/419 (23%)
Query: 888 GDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSPG 946
G+F S+ + SCD GY S E + C + +W+ +P+C+ + C +G V
Sbjct: 198 GNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQ 257
Query: 947 FPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSF--SEPVARL---- 1000
P +P + CT+ E +G +++ L T G++ +P +
Sbjct: 258 NPGSFPWNTTCTFDCE----EGFELM--------GAQSLQCTSSGNWDNEKPTCKAVTCR 305
Query: 1001 ------TGSVLPHTIKAGLFG-----NFTAQLRFISDFSISYEGFNITFSEYDLEPCDDP 1049
GSV AG F NFT + F+ E + C+
Sbjct: 306 AVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAF 365
Query: 1050 GVPAFSR----------RIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
A S F G S FSC G+ L+G+ +L C G W P
Sbjct: 366 QCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQC--GPTGEWDNEKP 423
Query: 1100 RCVA-ECGASVKGNEGTLLSPNFP-SNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT 1157
C A C A + +G + + P + C + E G +H T+
Sbjct: 424 TCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAF--SCEEGFELHGSTQ--------- 472
Query: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
L TS W E S +VK
Sbjct: 473 --------------------------LECTSQGQWTE--------------EVPSCQVVK 492
Query: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
C +P TV ++C G+ ++GS TC G W LP+C A
Sbjct: 493 CSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTC--GATGHWSGLLPTCEA 549
Score = 48.1 bits (113), Expect = 2e-04
Identities = 74/318 (23%), Positives = 117/318 (36%), Gaps = 72/318 (22%)
Query: 842 GNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGI------------------PVNG 883
GNF Y NS SI Y ++E+ C+ G P NG
Sbjct: 198 GNFSY------NSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANG 251
Query: 884 H----RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGK 938
++ G F +T TF C+ G+ L + L C + W++ P+C A+ C Q +
Sbjct: 252 FVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQ 311
Query: 939 SGTVLSPGFP-DFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPV 997
+G+V P + +C +T E F L+ + T G +++ +
Sbjct: 312 NGSVRCSHSPAGEFTFKSSCNFTCE-----------EGFMLQGPAQ-VECTTQGQWTQQI 359
Query: 998 A-----RLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYE-GFNITFS---------EYD 1042
+ T P + + R+ S S E GF + S E+D
Sbjct: 360 PVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWD 419
Query: 1043 LEP-------CDDPGVPAFSRRIGFHFGVGD-----SLTFSCFLGYRLEGATKLTCLGGG 1090
E CD P H +G+ S FSC G+ L G+T+L C G
Sbjct: 420 NEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQG 479
Query: 1091 RRVWSAPLPRC-VAECGA 1107
+ W+ +P C V +C +
Sbjct: 480 Q--WTEEVPSCQVVKCSS 495
Score = 46.6 bits (109), Expect = 4e-04
Identities = 48/228 (21%), Positives = 77/228 (33%), Gaps = 63/228 (27%)
Query: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAP-CGGQYTGSEGVVLS 1639
F+ GS+ + C+ G+ + + C G G+ WD P+C A C + +G+V
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQC--GPTGE--WDNEKPTCEAVRCDAVHQPPKGLVRC 443
Query: 1640 PNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGSH 1699
+ P G+F Y + E F+ H +L + G
Sbjct: 444 AHSP---------------------IGEFTYKSSCAFSCEEGFE-LHGSTQLECTSQGQW 481
Query: 1700 SGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEP-RYGRRIGSEF 1758
+ E VP +CSS+ P + E
Sbjct: 482 TEE-------------------------------VPSCQVVKCSSLAVPGKINMSCSGEP 510
Query: 1759 SAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGN 1806
G++ +F C G+ L GS A C A W+ +P+C P N
Sbjct: 511 VFGTVCKFACPEGWTLNGSAARTC----GATGHWSGLLPTCEAPTESN 554
Score = 43.1 bits (100), Expect = 0.005
Identities = 88/444 (19%), Positives = 150/444 (33%), Gaps = 103/444 (23%)
Query: 1215 LVKCEDPGIPNYGYRIRDE--GHFT-DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPL 1271
+V C P +G + G+F+ ++ SC+ GY T+ C+S W P+
Sbjct: 177 IVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE--WSAPI 234
Query: 1272 PSC-IAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH 1330
P+C + EC + A +G + P + N CT FD E
Sbjct: 235 PACNVVECDAVTNPA-NGFVECFQNPGSFPWNTTCT-----------------FDCEEGF 276
Query: 1331 DILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAA 1390
+++ + + T S + + T A
Sbjct: 277 ELMGA--------------------QSLQCT--------------SSGNWDNEKPTCKAV 302
Query: 1391 TCNDPGMPQNGTRYGDSREAGD-----TVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
TC PQNG+ AG+ + F C+ G+ LQG A++ C W
Sbjct: 303 TCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQ---WTQQI 359
Query: 1446 PTCIAACGGNLTGPAGVILS--PNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSY 1503
P C A L+ P ++ P+ + G C++ FV+ K P+
Sbjct: 360 PVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEF--SCEQGFVLK-GSKRLQCGPTG 416
Query: 1504 DFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLS---GFAIEFKEK 1560
+ ++ E + Q P+ + +S F +S S GF E
Sbjct: 417 E----WDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGF--ELHGS 470
Query: 1561 PREACFDPG---------NIMNGTRVGTDFKL----------GSTITYQCDSGYKILDPS 1601
+ C G ++ + + K+ G+ + C G+ + +
Sbjct: 471 TQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSA 530
Query: 1602 SITCVIGADGKPSWDQVLPSCNAP 1625
+ TC GA G W +LP+C AP
Sbjct: 531 ARTC--GATG--HWSGLLPTCEAP 550
Score = 43.1 bits (100), Expect = 0.005
Identities = 56/236 (23%), Positives = 80/236 (33%), Gaps = 30/236 (12%)
Query: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLSTLGGVILSPG 1990
+ N S C+ GY + CM W+ P P C + C + G +
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSG--EWSAPIPACNVVECDAVTNPANGFVECFQ 257
Query: 1991 FPGSYPNNLDCTWRISLPIG-YGAHIQFLNFSTEANHD----FLEIQNGPYHTSPMIGQF 2045
PGS+P N CT+ GA Q L ++ N D + P G
Sbjct: 258 NPGSFPWNTTCTFDCEEGFELMGA--QSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 2046 SGTDLPAALLSTTHETLIHFYSDHSQNRQG---FKLAYQAYELQNCPDPPPFQ------- 2095
+ PA T ++ +F + QG + Q Q P FQ
Sbjct: 316 RCSHSPAG--EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNP 373
Query: 2096 -NGYM-----INSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDA 2145
GYM + + G S F C G++L G L C G W+ P C+A
Sbjct: 374 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQC--GPTGEWDNEKPTCEA 427
Score = 41.6 bits (96), Expect = 0.014
Identities = 59/258 (22%), Positives = 93/258 (36%), Gaps = 36/258 (13%)
Query: 1742 CSSVPEPRYGRRIGSE----FSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
C+++ P +G + S FS S C+ GYL + C S +W+ IP
Sbjct: 180 CTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMS----SGEWSAPIP 235
Query: 1798 SC-VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQ-IQVISFATEQNWD 1855
+C VV C G + P + N C + EG + Q + + NWD
Sbjct: 236 ACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFD--CEEGFELMGAQSLQCTSSGNWD 293
Query: 1856 ----SLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAG-FHLEYKT 1910
+ + V P+ GS + PA + + +F + G +E T
Sbjct: 294 NEKPTCKAVTCRAVRQPQNGSVRCSHSPA--GEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 1911 VGLAACQEP---ALPSNSIKIGDRYMVNDVLS------------FQCEPGYTLQGRSHIS 1955
G Q P A ++ +R +N + S F CE G+ L+G +
Sbjct: 352 QGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQ 411
Query: 1956 CMPGTVRRWNYPSPLCIA 1973
C G W+ P C A
Sbjct: 412 C--GPTGEWDNEKPTCEA 427
Score = 40.4 bits (93), Expect = 0.032
Identities = 54/262 (20%), Positives = 95/262 (36%), Gaps = 46/262 (17%)
Query: 1580 DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA-PCGGQYTGSEGVVL 1638
+F S+ + CD GY ++ C+ + W +P+CN C + G V
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGE----WSAPIPACNVVECDAVTNPANGFVE 254
Query: 1639 SPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS----- 1693
P ++ C + + F + G + T+ + +D + ++
Sbjct: 255 CFQNPGSFPWNTTCTFDCE--EGFELMGAQSLQCTSSGN----WDNEKPTCKAVTCRAVR 308
Query: 1694 -----SLSGSHS--GETLPLATSNQILLRFSAKSGASARGFHFVY--------QAVPRTS 1738
S+ SHS GE ++ N F+ + G +G V Q +P
Sbjct: 309 QPQNGSVRCSHSPAGEFTFKSSCN-----FTCEEGFMLQGPAQVECTTQGQWTQQIPVCE 363
Query: 1739 DTQCSSVPEPRYGRR-----IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWN 1793
QC+++ P G F GS F C G++L+GS L C +W+
Sbjct: 364 AFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQC----GPTGEWD 419
Query: 1794 DTIPSC-VVPCSGNFTQRRGTI 1814
+ P+C V C +G +
Sbjct: 420 NEKPTCEAVRCDAVHQPPKGLV 441
Score = 34.3 bits (77), Expect = 2.3
Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 7/133 (5%)
Query: 1168 SRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYG 1227
S PLG F+ N + + +L T + + + ++V+C+ P G
Sbjct: 194 SHPLGNFSYNSSCSI--SCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANG 251
Query: 1228 YR--IRDEGHFT-DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHA 1284
+ ++ G F +T + C G+ + G+ +L C S WD P+C A +
Sbjct: 252 FVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN--WDNEKPTCKAVTCRAVRQ 309
Query: 1285 ATSGRILSPGYPA 1297
+G + PA
Sbjct: 310 PQNGSVRCSHSPA 322
Score = 34.3 bits (77), Expect = 2.3
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 2255 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
Q+ KC AVP ++ + G K+ C G+TL G+ TC + + G LP
Sbjct: 489 QVVKCSSL-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATG--HWSGLLP 545
Query: 2315 TCEAQCPAN 2323
TCEA +N
Sbjct: 546 TCEAPTESN 554
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 157 bits (396), Expect = 2e-37
Identities = 138/500 (27%), Positives = 203/500 (40%), Gaps = 98/500 (19%)
Query: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Y + G K QR + + R + + CG L+ +G +SP YP Y + HCV
Sbjct: 290 YEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCV 349
Query: 440 WVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
W I+ T +K+I L F +L R YD + V D + GS +P+ IV
Sbjct: 350 WRISVTPGEKII-LNFTSLDLYRSRLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIV 406
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
S +++W+ +S + GF AVY+ I CG YG
Sbjct: 407 STDSRLWVEFRSSSNWVGKGFFAVYEAI----CGGDVKKDYGH----------------- 445
Query: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Q N +PS V C + S G
Sbjct: 446 ------------IQSPNYPDDYRPSKV--CIWRIQVSEGF-------------------- 471
Query: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
+ L F F++E +D+L V+D T++G + G E P + S+ +
Sbjct: 472 ------HVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRL 525
Query: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
L+F SD S GF + + +EC P R G C+ + T
Sbjct: 526 WLKFVSDGSINKAGFAVNFFK-EVDECSRP------NRGG------------CEQRCLNT 566
Query: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
GS +C D + RCEA CGG LT +G I PGWP Y + +C W + A
Sbjct: 567 LGSYKCSC---DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
Query: 792 KPGHSIKITFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYL 847
+ I + FD F+TE N YD +EVR G + S L G++ G++ P+ + S N M +
Sbjct: 624 PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRV 683
Query: 848 LFTTDNSRSSIGFLIHYESV 867
F +DN+ S GF H+ SV
Sbjct: 684 EFKSDNTVSKKGFKAHFFSV 703
Score = 147 bits (370), Expect = 2e-34
Identities = 101/293 (34%), Positives = 142/293 (48%), Gaps = 36/293 (12%)
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
A CGG + G I SP YP Y + C W I+ G + L F F+ E A+D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
L+V DG +S L+ + G P+DI ST + L L+F SD I+K+GF++ F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE- 550
Query: 1392 CNDPGMPQNGTRYGDSREAGDTV---TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C+ P R G + +T+ CDPGY+L PD C
Sbjct: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYELA-----------------PDKRRC 587
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YD 1504
AACGG LT G I SP +P+ YPP K C W++ + I+L F F E + YD
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557
F+ + G ++S L G + GS+ PE I S N++ + F+SD +V GF F
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 141 bits (356), Expect = 1e-32
Identities = 94/286 (32%), Positives = 147/286 (51%), Gaps = 34/286 (11%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G+ + G I SP YP+ Y + CIW+I V+EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY-KTVGLAACQ 1917
+ DG ++ +G + G P + STS++L+L F SD S+ AGF + + K V C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD--ECS 552
Query: 1918 EPALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC 1975
P ++ +N + S++C +PGY L P R C A C
Sbjct: 553 RPNRGGC-----EQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAAC 591
Query: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEI 2031
GG L+ L G I SPG+P YP N +C W++ P Y +QF F TE N +DF+E+
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFK 2077
++G S + G+F G++ P + S + + F SD++ +++GFK
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Score = 139 bits (350), Expect = 5e-32
Identities = 91/294 (30%), Positives = 145/294 (49%), Gaps = 40/294 (13%)
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDF 1505
A CGG++ G I SPNYP Y P K C WR++V+ F + L F+SF +E +YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1506 LHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREAC 1565
L + +G +S LIG Y G + P+ I+S+ + L+L F SD S+ +GFA+ F ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1566 FDPGNIMNGTRVGTDFKLGSTI-TYQ--CDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
P R G + + +T+ +Y+ CD GY++ C
Sbjct: 552 SRP------NRGGCEQRCLNTLGSYKCSCDPGYELAPDKR------------------RC 587
Query: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDL---- 1678
A CGG T G + SP +P Y + C++ + P ++ + QF +F+T ND+
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1679 -AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF--HF 1729
E+ G A ++L GS E + + N + + F + + S +GF HF
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 125 bits (314), Expect = 7e-28
Identities = 88/292 (30%), Positives = 135/292 (46%), Gaps = 32/292 (10%)
Query: 756 EAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YD 811
EA CGG + G I P +P Y+ S C W I+ G + +TF F+ E + YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 812 TLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLES 871
LEVRDG + SS LIG Y G + P + ST + ++L F +D S + GF +++ E
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EV 548
Query: 872 DSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALC 931
D C P G + SCDPGY L+ D+ C+A C
Sbjct: 549 DECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAAC 591
Query: 932 GGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESS----HDYLLI 987
GG++ +G++ SPG+P YP + NC W + + + F F E + +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 988 TED-GSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
+ S+ + GS P I + N ++ F SD ++S +GF F
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVI-TSQYNNM--RVEFKSDNTVSKKGFKAHF 700
Score = 123 bits (308), Expect = 4e-27
Identities = 118/467 (25%), Positives = 186/467 (39%), Gaps = 101/467 (21%)
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLE 2030
CG TL G SP +P Y ++ C WRIS+ G + F + + +D++E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPD 2090
+++G + +P+ G+F G+ LP ++ST + F S + +GF Y+A C
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----C-- 435
Query: 2091 PPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
G + DY QS NYP
Sbjct: 436 ------GGDVKKDYGHIQSP--------------------------NYP----------- 452
Query: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAVWDG 2206
D+Y K CIW I V G V + F + E DY+ V DG
Sbjct: 453 --------------DDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG 498
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
++S +G + G + S+++++ LKF SD S N F +NF ++ +C P
Sbjct: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSRPNRG 557
Query: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
+ +G + K C PGY L CEA C
Sbjct: 558 GCEQRCLN----TLGSY-KCSCDPGYELA----------------PDKRRCEAAC--GGF 594
Query: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----QFDALEVFDG 2381
T +G I SPG+P Y ++ C W + Y I++ D F++E ++D +EV G
Sbjct: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
Query: 2382 SSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2428
+ S L G+ + TS+ N + + + +D+ SKKGFK +
Sbjct: 655 LTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 122 bits (307), Expect = 5e-27
Identities = 83/276 (30%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
A CGG + G I SP +P Y + C WRI + G+ + F +F E + +D+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
LE+++G +S +IG++ G + P + ST+ + F SD S N+ GF + + E+ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
P G + S C PGY L RC+A CG
Sbjct: 552 SRP---NRGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEAACG 592
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVW 2204
+T NG+I SPG+P EYP K+CIW + P + + + F +TE + D++ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
G +S G F G+ E S N + ++F SD
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSD 688
Score = 118 bits (295), Expect = 1e-25
Identities = 93/290 (32%), Positives = 127/290 (43%), Gaps = 36/290 (12%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CGG V+ G I+SP +P Y C W I E + L+F +F +E +D L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG + L R G++ P I ST S L L F +D +++ GF A+ C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-AVNFFKEVDECSR 553
Query: 148 PGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGA 207
P +G N + SC PGY L +P R E A
Sbjct: 554 PN---RGGCEQRCLNTLGSYKCSCDPGYEL----------APDKR----------RCEAA 590
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263
CGG L + SI+SP +P EY N +C W ++A I+L F F+ E YDF+E
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 264 I-SGTEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQF 309
+ SG A S G P + S N +R+ F SD+ +KGF A F
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 103 bits (256), Expect = 4e-21
Identities = 99/381 (25%), Positives = 156/381 (40%), Gaps = 48/381 (12%)
Query: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
A CGG G + SPNYP +Y ++C++ I V + F V F F+ + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHF-VYQAVPRT 1737
E+ DG + L+ G + + +TS+++ L+F + + GF ++ V
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1738 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
S E R +GS + C+PGY L
Sbjct: 552 SRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR------------------ 585
Query: 1798 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1853
C C G T+ G+I SPG+P+ Y N NCIW+++ I +Q F TE N
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 1854 WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV-G 1912
+D +E+ G + G F G+ P ++ S N + + F+SD +V+ GF + +V
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLE 705
Query: 1913 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
A + L + + +V+ V + P L G +H T + P+
Sbjct: 706 GAGDRHSHLSGLELLLCPHALVDTVPA----PPSALHGDTHAH----THTHVHTHCPIAQ 757
Query: 1973 ATCGGTLSTLGGVILSPGFPG 1993
TC G LG LSP PG
Sbjct: 758 ETCRG--PPLGASRLSPQGPG 776
Score = 96.7 bits (239), Expect = 4e-19
Identities = 81/295 (27%), Positives = 132/295 (44%), Gaps = 34/295 (11%)
Query: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLE----SSHD 983
+A+CGG ++ G + SP +PD Y S C W I+VS G V + F +F +E ++D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 984 YLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
YL + + S S + R G P IK+ + L+F+SD SI+ GF + F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
++ C P +R G S SC GY L + RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK--- 1159
A CG + G++ SP +P Y N CI+++ I L+ F+ D K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1160 --VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
V G + S+ G F +E ++ S N++ +EF ++ + + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCGSE-KPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 94.7 bits (234), Expect = 1e-18
Identities = 87/348 (25%), Positives = 140/348 (40%), Gaps = 71/348 (20%)
Query: 191 NGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF 250
+ ++W F E CGG ++ I SP++P +Y + C W I G + L F
Sbjct: 418 SSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF 477
Query: 251 TDFQLEE----GYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHRR 302
F++E YD+LE+ + S L G P + S+ + L L F SD + +
Sbjct: 478 QSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINK 537
Query: 303 KGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAG 362
GF F K ++ SR P++ G + + + G
Sbjct: 538 AGFAVNF--FKEVDECSR-----PNRGGCEQRCLNTLG---------------------- 568
Query: 363 SDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV 422
+ + SC+ Y L K C A CG L +G
Sbjct: 569 --------SYKCSCDPGYELAPDKR------------------RCEA-ACGGFLTKLNGS 601
Query: 423 ITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDT 478
ITSP +P +Y N +C+W + + I L F+ FE E YD + V +G D+
Sbjct: 602 ITSPGWPKEYPPNKNCIWQLVAPTQYR-ISLQFDFFETEGNDVCKYDFVEV-RSGLTADS 659
Query: 479 RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKG 526
+ + GS P++I S N M + +SD+++ GFKA + + +G
Sbjct: 660 K-LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLEG 706
Score = 66.6 bits (161), Expect = 4e-10
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
ACG L G SP YP Y C WR+ V P I L F S ++ S YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDAS-VGLSGFAI 1555
+ +G +PL G + GS+ PE I S+ + L++ FRS ++ VG FA+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 65.9 bits (159), Expect = 7e-10
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
ACG TL+ ++ + SSP +P+ Y + C W I PG+ I L FT L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
E+ +AP G LP P++S+ + L + F S SN KGF A ++
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 63.5 bits (153), Expect = 3e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CG +Q G SP +P+GY + +C W I +I L+F + L +D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG ++ L+ R G +LP IVST S L + F + +GF A+YE + CG
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CG- 436
Query: 148 PGEILKGVLHGTRFNIGDKIRYS 170
G++ K H N D R S
Sbjct: 437 -GDVKKDYGHIQSPNYPDDYRPS 458
Score = 62.0 bits (149), Expect = 1e-08
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G SP YP Y +++C+W+I VT G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
+ DG AP G F G+ +P + ST ++L++ F+S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 59.3 bits (142), Expect = 7e-08
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 16/169 (9%)
Query: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNT----LTCLSGDRRVWDKPLPSCIAEC 1278
I +Y G F DT+V P Y ++G T LS + L C A C
Sbjct: 269 IMHYARNTFSRGIFLDTIV-----PKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPA-C 322
Query: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
G + +T G SP YP Y ++HC W I PG+ I L+F D + +D ++
Sbjct: 323 GETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQF-DSDFFISKSGFSI 1382
V DG L + GS LPE I ST + L ++F S ++ K F++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 57.4 bits (137), Expect = 3e-07
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
+C A CG + G SP +P+ Y C+W I+V PG + +NFT L
Sbjct: 318 KCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCW 376
Query: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFFVL 2249
DY+ V DG + +P G F G+ E S+ +++ ++F S++ GFF +
Sbjct: 377 YDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 53.1 bits (126), Expect = 5e-06
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 1085 TCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
T L G + L +C A CG +++ + G SP +P+ Y + C+++I G+ I
Sbjct: 303 TRLSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII 361
Query: 1145 LRTRSFQLFEG-----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNG 1199
L S L+ D ++V DG + G F ++L I+ ST + LW+EF ++
Sbjct: 362 LNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV-STDSRLWVEFRSSS 420
Query: 1200 SDTDQGFQLTY 1210
+ +GF Y
Sbjct: 421 NWVGKGFFAVY 431
Score = 47.0 bits (110), Expect = 3e-04
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
CG S G SP YP+ Y+A C++ I+V P E ++ F +++ L D E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
+ DG +A L GS E + ++T +++ + F + S +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 42.0 bits (97), Expect = 0.011
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 924 LPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESS-- 981
L C A CG +Q +G SP +P+ Y ++C W I V+ G+ + + F + L S
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 982 --HDYLLITEDGSFSEPV-ARLTGSVLPHTI 1009
+DY+ + + P+ R GS LP I
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI 405
Score = 41.2 bits (95), Expect = 0.019
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
+CPA E S+G SP YP Y C W I V P I + +D ++S +
Sbjct: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
D +EV DG ++PL G+ + S ++L++ + + KGF Y A
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEP-IVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 155 bits (392), Expect = 7e-37
Identities = 137/499 (27%), Positives = 202/499 (40%), Gaps = 98/499 (19%)
Query: 380 YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCV 439
Y + G K QR + + R + + CG L+ +G +SP YP Y + HCV
Sbjct: 290 YEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCV 349
Query: 440 WVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
W I+ T +K+I L F +L R YD + V D + GS +P+ IV
Sbjct: 350 WRISVTPGEKII-LNFTSLDLYRSRLCWYDYVEVRDG--FWRKAPLRGRFCGSKLPEPIV 406
Query: 496 SMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECP 555
S +++W+ +S + GF AVY+ I CG YG
Sbjct: 407 STDSRLWVEFRSSSNWVGKGFFAVYEAI----CGGDVKKDYGH----------------- 445
Query: 556 AAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLI 615
Q N +PS V C + S G
Sbjct: 446 ------------IQSPNYPDDYRPSKV--CIWRIQVSEGF-------------------- 471
Query: 616 ISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
+ L F F++E +D+L V+D T++G + G E P + S+ +
Sbjct: 472 ------HVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRL 525
Query: 672 RLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKT 731
L+F SD S GF + + +EC P R G C+ + T
Sbjct: 526 WLKFVSDGSINKAGFAVNFFK-EVDECSRP------NRGG------------CEQRCLNT 566
Query: 732 QGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEA 791
GS +C D + RCEA CGG LT +G I PGWP Y + +C W + A
Sbjct: 567 LGSYKCSC---DPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA 623
Query: 792 KPGHSIKITFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYL 847
+ I + FD F+TE N YD +EVR G + S L G++ G++ P+ + S N M +
Sbjct: 624 PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRV 683
Query: 848 LFTTDNSRSSIGFLIHYES 866
F +DN+ S GF H+ S
Sbjct: 684 EFKSDNTVSKKGFKAHFFS 702
Score = 149 bits (377), Expect = 4e-35
Identities = 104/304 (34%), Positives = 146/304 (48%), Gaps = 36/304 (11%)
Query: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
A CGG + G I SP YP Y + C W I+ G + L F F+ E A+D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
L+V DG +S L+ + G P+DI ST + L L+F SD I+K+GF++ F +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE- 550
Query: 1392 CNDPGMPQNGTRYGDSREAGDTV---TFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C+ P R G + +T+ CDPGY+L PD C
Sbjct: 551 CSRPN------RGGCEQRCLNTLGSYKCSCDPGYELA-----------------PDKRRC 587
Query: 1449 IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YD 1504
AACGG LT G I SP +P+ YPP K C W++ + I+L F F E + YD
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREA 1564
F+ + G ++S L G + GS+ PE I S N++ + F+SD +V GF F + R A
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPA 707
Query: 1565 CFDP 1568
P
Sbjct: 708 LQPP 711
Score = 141 bits (356), Expect = 1e-32
Identities = 94/286 (32%), Positives = 147/286 (51%), Gaps = 34/286 (11%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G+ + G I SP YP+ Y + CIW+I V+EG + + SF E++ +D LE
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY-KTVGLAACQ 1917
+ DG ++ +G + G P + STS++L+L F SD S+ AGF + + K V C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVD--ECS 552
Query: 1918 EPALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC 1975
P ++ +N + S++C +PGY L P R C A C
Sbjct: 553 RPNRGGC-----EQRCLNTLGSYKCSCDPGYELA--------PDKRR--------CEAAC 591
Query: 1976 GGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEI 2031
GG L+ L G I SPG+P YP N +C W++ P Y +QF F TE N +DF+E+
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFK 2077
++G S + G+F G++ P + S + + F SD++ +++GFK
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Score = 140 bits (352), Expect = 3e-32
Identities = 92/300 (30%), Positives = 147/300 (49%), Gaps = 40/300 (13%)
Query: 1450 AACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDF 1505
A CGG++ G I SPNYP Y P K C WR++V+ F + L F+SF +E +YD+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1506 LHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREAC 1565
L + +G +S LIG Y G + P+ I+S+ + L+L F SD S+ +GFA+ F ++ E C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDE-C 551
Query: 1566 FDPGNIMNGTRVGTDFKLGSTI-TYQ--CDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
P R G + + +T+ +Y+ CD GY++ C
Sbjct: 552 SRP------NRGGCEQRCLNTLGSYKCSCDPGYELAPDKR------------------RC 587
Query: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDL---- 1678
A CGG T G + SP +P Y + C++ + P ++ + QF +F+T ND+
Sbjct: 588 EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 1679 -AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF--HFVYQAVP 1735
E+ G A ++L GS E + + N + + F + + S +GF HF + P
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVI-TSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRP 706
Score = 125 bits (314), Expect = 7e-28
Identities = 88/292 (30%), Positives = 135/292 (46%), Gaps = 32/292 (10%)
Query: 756 EAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YD 811
EA CGG + G I P +P Y+ S C W I+ G + +TF F+ E + YD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 812 TLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLES 871
LEVRDG + SS LIG Y G + P + ST + ++L F +D S + GF +++ E
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK---EV 548
Query: 872 DSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALC 931
D C P G + SCDPGY L+ D+ C+A C
Sbjct: 549 DECSRPN---RGGCEQRCLNTLGSYKCSCDPGYELAPDKR--------------RCEAAC 591
Query: 932 GGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESS----HDYLLI 987
GG++ +G++ SPG+P YP + NC W + + + F F E + +D++ +
Sbjct: 592 GGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 988 TED-GSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF 1038
+ S+ + GS P I + N ++ F SD ++S +GF F
Sbjct: 652 RSGLTADSKLHGKFCGSEKPEVI-TSQYNNM--RVEFKSDNTVSKKGFKAHF 700
Score = 125 bits (314), Expect = 7e-28
Identities = 93/306 (30%), Positives = 138/306 (45%), Gaps = 35/306 (11%)
Query: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
A CGG + G I SP +P Y + C WRI + G+ + F +F E + +D+
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
LE+++G +S +IG++ G + P + ST+ + F SD S N+ GF + + E+ C
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDEC 551
Query: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
P G + S C PGY L RC+A CG
Sbjct: 552 SRP---NRGGCEQRCLNTLGSYKCSCDPGYELAPDK----------------RRCEAACG 592
Query: 2149 YNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVW 2204
+T NG+I SPG+P EYP K+CIW + P + + + F +TE + D++ V
Sbjct: 593 GFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVR 652
Query: 2205 DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLKK--CQ 2260
G +S G F G+ E S N + ++F SD S GF H F K+ Q
Sbjct: 653 SGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF---KAHFFSEKRPALQ 709
Query: 2261 PPPAVP 2266
PP P
Sbjct: 710 PPRGRP 715
Score = 123 bits (308), Expect = 4e-27
Identities = 118/467 (25%), Positives = 186/467 (39%), Gaps = 101/467 (21%)
Query: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLE 2030
CG TL G SP +P Y ++ C WRIS+ G + F + + +D++E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPD 2090
+++G + +P+ G+F G+ LP ++ST + F S + +GF Y+A C
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----C-- 435
Query: 2091 PPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
G + DY QS NYP
Sbjct: 436 ------GGDVKKDYGHIQSP--------------------------NYP----------- 452
Query: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAVWDG 2206
D+Y K CIW I V G V + F + E DY+ V DG
Sbjct: 453 --------------DDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDG 498
Query: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAFQLKKCQPPPAV 2265
++S +G + G + S+++++ LKF SD S N F +NF ++ +C P
Sbjct: 499 HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK-EVDECSRPNRG 557
Query: 2266 PQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEV 2325
+ +G + K C PGY L CEA C
Sbjct: 558 GCEQRCLN----TLGSY-KCSCDPGYELA----------------PDKRRCEAAC--GGF 594
Query: 2326 RTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----QFDALEVFDG 2381
T +G I SPG+P Y ++ C W + Y I++ D F++E ++D +EV G
Sbjct: 595 LTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSG 654
Query: 2382 SSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2428
+ S L G+ + TS+ N + + + +D+ SKKGFK +
Sbjct: 655 LTADSKLHGKFCGSEKPEV-ITSQYNNMRVEFKSDNTVSKKGFKAHF 700
Score = 118 bits (296), Expect = 9e-26
Identities = 94/294 (31%), Positives = 129/294 (43%), Gaps = 36/294 (12%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CGG V+ G I+SP +P Y C W I E + L+F +F +E +D L
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG + L R G++ P I ST S L L F +D +++ GF A+ C
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF-AVNFFKEVDECSR 553
Query: 148 PGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGA 207
P +G N + SC PGY L +P R E A
Sbjct: 554 PN---RGGCEQRCLNTLGSYKCSCDPGYEL----------APDKR----------RCEAA 590
Query: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263
CGG L + SI+SP +P EY N +C W ++A I+L F F+ E YDF+E
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 264 I-SGTEAPSIW---LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
+ SG A S G P + S N +R+ F SD+ +KGF A F +K
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEK 704
Score = 103 bits (256), Expect = 4e-21
Identities = 81/306 (26%), Positives = 129/306 (42%), Gaps = 37/306 (12%)
Query: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
A CGG G + SPNYP +Y ++C++ I V + F V F F+ + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHF-VYQAVPRT 1737
E+ DG + L+ G + + +TS+++ L+F + + GF ++ V
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIK-STSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 1738 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
S E R +GS + C+PGY L
Sbjct: 552 SRPNRGGC-EQRCLNTLGS-------YKCSCDPGYELAPDKR------------------ 585
Query: 1798 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1853
C C G T+ G+I SPG+P+ Y N NCIW+++ I +Q F TE N
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 1854 WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGL 1913
+D +E+ G + G F G+ P ++ S N + + F+SD +V+ GF + +
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKR 705
Query: 1914 AACQEP 1919
A Q P
Sbjct: 706 PALQPP 711
Score = 96.7 bits (239), Expect = 4e-19
Identities = 81/295 (27%), Positives = 132/295 (44%), Gaps = 34/295 (11%)
Query: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLE----SSHD 983
+A+CGG ++ G + SP +PD Y S C W I+VS G V + F +F +E ++D
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 984 YLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042
YL + + S S + R G P IK+ + L+F+SD SI+ GF + F + +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKS---TSSRLWLKFVSDGSINKAGFAVNFFK-E 547
Query: 1043 LEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
++ C P +R G S SC GY L + RC
Sbjct: 548 VDECSRPNRGGCEQRCLNTLG---SYKCSCDPGYELAPDKR----------------RCE 588
Query: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLK--- 1159
A CG + G++ SP +P Y N CI+++ I L+ F+ D K
Sbjct: 589 AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDF 648
Query: 1160 --VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
V G + S+ G F +E ++ S N++ +EF ++ + + +GF+ + S
Sbjct: 649 VEVRSGLTADSKLHGKFCGSE-KPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702
Score = 93.2 bits (230), Expect = 4e-18
Identities = 86/340 (25%), Positives = 136/340 (40%), Gaps = 71/340 (20%)
Query: 191 NGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF 250
+ ++W F E CGG ++ I SP++P +Y + C W I G + L F
Sbjct: 418 SSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTF 477
Query: 251 TDFQLEE----GYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHRR 302
F++E YD+LE+ + S L G P + S+ + L L F SD + +
Sbjct: 478 QSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINK 537
Query: 303 KGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAG 362
GF F K ++ SR P++ G + + + G
Sbjct: 538 AGFAVNF--FKEVDECSR-----PNRGGCEQRCLNTLG---------------------- 568
Query: 363 SDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV 422
+ + SC+ Y L K C A CG L +G
Sbjct: 569 --------SYKCSCDPGYELAPDKR------------------RCEA-ACGGFLTKLNGS 601
Query: 423 ITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDT 478
ITSP +P +Y N +C+W + + I L F+ FE E YD + V +G D+
Sbjct: 602 ITSPGWPKEYPPNKNCIWQLVAPTQYR-ISLQFDFFETEGNDVCKYDFVEV-RSGLTADS 659
Query: 479 RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKA 518
+ + GS P++I S N M + +SD+++ GFKA
Sbjct: 660 K-LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 698
Score = 66.6 bits (161), Expect = 4e-10
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
ACG L G SP YP Y C WR+ V P I L F S ++ S YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDAS-VGLSGFAI 1555
+ +G +PL G + GS+ PE I S+ + L++ FRS ++ VG FA+
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 65.9 bits (159), Expect = 7e-10
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
ACG TL+ ++ + SSP +P+ Y + C W I PG+ I L FT L YD++
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
E+ +AP G LP P++S+ + L + F S SN KGF A ++
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYE 432
Score = 63.5 bits (153), Expect = 3e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
CG +Q G SP +P+GY + +C W I +I L+F + L +D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGN 147
V DG ++ L+ R G +LP IVST S L + F + +GF A+YE + CG
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI----CG- 436
Query: 148 PGEILKGVLHGTRFNIGDKIRYS 170
G++ K H N D R S
Sbjct: 437 -GDVKKDYGHIQSPNYPDDYRPS 458
Score = 62.0 bits (149), Expect = 1e-08
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
C G SP YP Y +++C+W+I VT G I + S ++ +D +E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
+ DG AP G F G+ +P + ST ++L++ F+S + GF Y+ +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 59.3 bits (142), Expect = 7e-08
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 16/169 (9%)
Query: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNT----LTCLSGDRRVWDKPLPSCIAEC 1278
I +Y G F DT+V P Y ++G T LS + L C A C
Sbjct: 269 IMHYARNTFSRGIFLDTIV-----PKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPA-C 322
Query: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
G + +T G SP YP Y ++HC W I PG+ I L+F D + +D ++
Sbjct: 323 GETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQF-DSDFFISKSGFSI 1382
V DG L + GS LPE I ST + L ++F S ++ K F++
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 57.4 bits (137), Expect = 3e-07
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
+C A CG + G SP +P+ Y C+W I+V PG + +NFT L
Sbjct: 318 KCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCW 376
Query: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFFVL 2249
DY+ V DG + +P G F G+ E S+ +++ ++F S++ GFF +
Sbjct: 377 YDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAV 430
Score = 53.1 bits (126), Expect = 5e-06
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 1085 TCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIH 1144
T L G + L +C A CG +++ + G SP +P+ Y + C+++I G+ I
Sbjct: 303 TRLSKGDIAQARKLYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKII 361
Query: 1145 LRTRSFQLFEG-----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNG 1199
L S L+ D ++V DG + G F ++L I+ ST + LW+EF ++
Sbjct: 362 LNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV-STDSRLWVEFRSSS 420
Query: 1200 SDTDQGFQLTY 1210
+ +GF Y
Sbjct: 421 NWVGKGFFAVY 431
Score = 47.0 bits (110), Expect = 3e-04
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
CG S G SP YP+ Y+A C++ I+V P E ++ F +++ L D E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAV 1734
+ DG +A L GS E + ++T +++ + F + S +GF VY+A+
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPI-VSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 42.0 bits (97), Expect = 0.011
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 924 LPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESS-- 981
L C A CG +Q +G SP +P+ Y ++C W I V+ G+ + + F + L S
Sbjct: 316 LYKCPA-CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL 374
Query: 982 --HDYLLITEDGSFSEPV-ARLTGSVLPHTI 1009
+DY+ + + P+ R GS LP I
Sbjct: 375 CWYDYVEVRDGFWRKAPLRGRFCGSKLPEPI 405
Score = 41.2 bits (95), Expect = 0.019
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
+CPA E S+G SP YP Y C W I V P I + +D ++S +
Sbjct: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
D +EV DG ++PL G+ + S ++L++ + + KGF Y A
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEP-IVSTDSRLWVEFRSSSNWVGKGFFAVYEA 433
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 150 bits (378), Expect = 3e-35
Identities = 138/491 (28%), Positives = 191/491 (38%), Gaps = 55/491 (11%)
Query: 2753 SEFNLNDVVNFTCNTGYLLQGVSRA-QCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQ 2811
+ F + +TC GY+ ++ C S+G+W C C PG +R+GQ
Sbjct: 69 TRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPG----ELRNGQ 123
Query: 2812 QNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGL---WDRSLPKCLAISCGHPGVPAN 2868
+G I + C +GF+L+GS+ C W LP+C + C P N
Sbjct: 124 VEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRN 183
Query: 2869 AVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVCQEDSH----WSGALPHCTGNNPGFCG 2922
+GE + YG V YSC SL+G+ + C ++ W + P C C
Sbjct: 184 GRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKIT---CR 240
Query: 2923 DPGTPAHG---SRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSC 2979
P +HG S G + K + F C+ G LRGS C + W+ P CE SC
Sbjct: 241 KPDV-SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSC 299
Query: 2980 GN-PGTP-----TNGMIVSSDGILFSSSVIYACWEGYK--TSGLMTRHCTANGTWTGTAP 3031
N P P T D + + + Y C GYK T T C N WT
Sbjct: 300 INLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQ 358
Query: 3032 DCTIISCGDPGTLANG--IQFGTD-------FTFNKTVSYQCNPGYVMEAVTSATIRCTK 3082
C + C +P L NG Q + + +S+ C+ A+ C
Sbjct: 359 GCEALCCPEP-KLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAI------CQG 411
Query: 3083 DGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFR--WGSSISYSCMDGYQLSHSAILSCEG 3140
DG W+P P C +C PP + +G + S + I Y C GY L A LSC
Sbjct: 412 DGTWSPRTPSC-GDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSC-S 469
Query: 3141 RGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTY--KSEVFFQCKSPFILVGSSRRVCQA 3198
W PQC C P + GRLS Y V QC S + +VG C
Sbjct: 470 YSHWSAPAPQC-KALCRKPEL-VNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSG 527
Query: 3199 DGTWSGIQPTC 3209
+ TW P C
Sbjct: 528 NRTWYPEVPKC 538
Score = 148 bits (373), Expect = 1e-34
Identities = 118/453 (26%), Positives = 187/453 (41%), Gaps = 53/453 (11%)
Query: 2432 YCSLTHP--LKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTP 2489
Y HP L+NG + +T + GS++ + C G+ ++G + + C G+ W P
Sbjct: 110 YKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV-GWSHPLP 168
Query: 2490 LCQAVSCGIPESPGNGSFTGNE--FTLDSKVVYECHEGFKL--ESSQQATAVCQEDGLWS 2545
C+ V C P NG +G E + V Y C F L +S T + G+W
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW- 227
Query: 2546 NKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQA 2605
+ PPTC+ + C + E V G + Y ++ C G+ L G ++ C A
Sbjct: 228 -RPSPPTCEKITCRKPDVSHGEMVSG---FGPIYNYKDTIVFKCQKGFVLRGSSVIHCDA 283
Query: 2606 NGTWNIGDERPSCRVISCGSLSFPPNGN-------KIGTLTVYGATAIFTCNTGY--TLV 2656
+ WN P+C SC +L P+ + + V G + C+ GY T
Sbjct: 284 DSKWN--PSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTD 341
Query: 2657 GSHVRECLANGLWS---GSETRCLAGHCGSPDPIVNGHISGDG---------FSYRDTVV 2704
C N W+ G E C C P + NG I+ + Y D +
Sbjct: 342 EPTTVICQKNLRWTPYQGCEALC----CPEP-KLNNGEITQHRKSRPANHCVYFYGDEIS 396
Query: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHG-FTNGSEFN-LNDVVN 2762
+ C+ R IC D WS +TP C I C P AHG + S ++ + +
Sbjct: 397 FSCHETSRFSA----ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEII 451
Query: 2763 FTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGM 2822
+ C+ GY+L G ++ C S WS+P P C+ + C P V + + + E
Sbjct: 452 YECDKGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKPELVNGRLSVDKDQYVEP----E 505
Query: 2823 SILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
++ C G+ ++G ++TC N W +PKC
Sbjct: 506 NVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 144 bits (362), Expect = 2e-33
Identities = 104/356 (29%), Positives = 158/356 (44%), Gaps = 40/356 (11%)
Query: 3004 YACWEGY-KTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANG-IQFGTDFTFNKTVS 3061
Y C GY ++ T C ++G W C C PG L NG ++ TD +F +
Sbjct: 79 YTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRNGQVEIKTDLSFGSQIE 137
Query: 3062 YQCNPGYVMEAVTSATIRCTKDGR---WNPSKPVCKAVLCPQPPPVQNGTVEGSD--FRW 3116
+ C+ G+ + + S T RC R W+ P C+ V C PP ++NG G + + +
Sbjct: 138 FSCSEGFFL--IGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAY 195
Query: 3117 GSSISYSCMDGYQLSHSAILSC----EGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKS- 3171
G S++YSC + L A +SC E GVW+ P C + C P + +SG
Sbjct: 196 GFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGP 255
Query: 3172 -FTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD-PGTPHFGIQN 3229
+ YK + F+C+ F+L GSS C AD W+ P C +P N+C + P PH +
Sbjct: 256 IYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPAC-EP--NSCINLPDIPHASWET 312
Query: 3230 SSRG-----YEVGSTVFFRCRKGYH--IQGSTTRTCLANLTWSGIQTECIPHACRQP--- 3279
R Y VG+ + +RC GY TT C NL W+ Q C C +P
Sbjct: 313 YPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQ-GCEALCCPEPKLN 371
Query: 3280 --ETPAHADVRAID--LPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
E H R + + +G + ++CH + C+ D W+ ++P C
Sbjct: 372 NGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSA-----ICQGDGTWSPRTPSC 422
Score = 134 bits (337), Expect = 2e-30
Identities = 138/552 (25%), Positives = 201/552 (36%), Gaps = 64/552 (11%)
Query: 2852 LPKCLAISCGHP-----GVPANAVLTGELFTYGAVVHYSCR-GSESLIGNDTRVCQEDSH 2905
LP L +CG P P + LT F G + Y+C G T C D
Sbjct: 43 LPAVLG-NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGE 101
Query: 2906 WSGALPHCTGNNPGFCGDPGTPAHGS-RLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLN 2964
W C C PG +G + D S + FSC G L GS C +
Sbjct: 102 WVYNT-FCIYKR---CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQ 157
Query: 2965 G---SWSGLQPVCEAVSCGNPGTPTNGMIVSSDGIL-FSSSVIYACWEGYKTSGLMTRHC 3020
WS P CE V C P NG + + SV Y+C + G + C
Sbjct: 158 DRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISC 217
Query: 3021 TAN----GTWTGTAPDCTIISCGDP----GTLANGIQFGTDFTFNKTVSYQCNPGYVMEA 3072
T G W + P C I+C P G + +G FG + + T+ ++C G+V+
Sbjct: 218 TVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSG--FGPIYNYKDTIVFKCQKGFVLRG 275
Query: 3073 VTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSD-------FRWGSSISYSCM 3125
S+ I C D +WNPS P C+ C P + + + E + G+ + Y C
Sbjct: 276 --SSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCH 333
Query: 3126 DGYQ--LSHSAILSCEGRGVWKGEIPQCLPVFCGDP----GIPAEGRLSGKS----FTYK 3175
GY+ + C+ W C + C +P G + R S + + Y
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYG 392
Query: 3176 SEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYE 3235
E+ F C +CQ DGTWS P+C D C P G S Y
Sbjct: 393 DEISFSCHE----TSRFSAICQGDGTWSPRTPSCGD----ICNFPPKIAHGHYKQSSSYS 444
Query: 3236 -VGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPT 3294
+ + C KGY + G +C + WS +C CR+PE D
Sbjct: 445 FFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQC-KALCRKPELVNGRLSVDKDQYV 502
Query: 3295 FGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTK------TPV 3348
+ C G+ + G + TC + W + P C+ + + +T P
Sbjct: 503 EPENVTIQCDSGYGVV-GPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPN 561
Query: 3349 PSDVFFVNSLWK 3360
P DV ++K
Sbjct: 562 PEDVKMALEVYK 573
Score = 134 bits (336), Expect = 2e-30
Identities = 130/537 (24%), Positives = 203/537 (37%), Gaps = 72/537 (13%)
Query: 2481 MYQWDSLTPLCQAV--SCGIPES-----PGNGSFTGNEFTLDSKVVYECHEGFKLESSQQ 2533
++Q + L AV +CG P + P + + T F + + Y C G+ S Q
Sbjct: 33 LFQMTLIAALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQ 92
Query: 2534 ATAVCQEDGLWS-------NKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL 2586
T C DG W + + P I+ LS +G+Q+
Sbjct: 93 -TLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLS--------------FGSQIE 137
Query: 2587 LSCSPGYYLEGWRLLRCQANGT---WNIGDERPSCRVISCGSLSFPPNGNKIG--TLTVY 2641
SCS G++L G RC+ W+ P C ++ C NG G Y
Sbjct: 138 FSCSEGFFLIGSTTSRCEVQDRGVGWS--HPLPQCEIVKCKPPPDIRNGRHSGEENFYAY 195
Query: 2642 GATAIFTCNTGYTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPDPIVNGHISGDG- 2696
G + ++C+ ++L+G C G+W S C C PD +SG G
Sbjct: 196 GFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGP 255
Query: 2697 -FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGF------ 2749
++Y+DT+V++C GF L G+SV C D KW+ P C P +C + + H
Sbjct: 256 IYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPR 315
Query: 2750 -TNGSEFNLNDVVNFTCNTGY--LLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA 2806
T + + V+ + C+ GY + C+ N +W +P C + C +P
Sbjct: 316 PTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRW-TPYQGCEALCCPEPKLNNGE 374
Query: 2807 IRHGQQNFPES---FEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHP 2863
I +++ P + + YG I + C + + C +G W P C I C P
Sbjct: 375 ITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQGDGTWSPRTPSCGDI-CNFP 429
Query: 2864 GVPANA--VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFC 2921
A+ + + + Y C L+G C SHWS P C C
Sbjct: 430 PKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY-SHWSAPAPQC----KALC 484
Query: 2922 GDPGTPAHGSRLG---DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCE 2975
P RL D + + C+ G+ + G TC N +W P CE
Sbjct: 485 RKP--ELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCE 539
Score = 126 bits (317), Expect = 3e-28
Identities = 125/508 (24%), Positives = 202/508 (39%), Gaps = 58/508 (11%)
Query: 2445 LNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGN 2504
L T G+ + Y C PGY + HS T N G + +++ C C P N
Sbjct: 66 LTETRFKTGTTLKYTCLPGY-VRSHSTQTLTCNSDGEWVYNT---FCIYKRCRHPGELRN 121
Query: 2505 GSF-TGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGL-WSNKGKPPTCKPVAC-PSI 2561
G + + S++ + C EGF L S + Q+ G+ WS+ P C+ V C P
Sbjct: 122 GQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSH--PLPQCEIVKCKPPP 179
Query: 2562 EAQLSEHVIWRLVSGSLN--EYGAQVLLSCSPGYYLEGWRLLRC----QANGTWNIGDER 2615
+ + H SG N YG V SC P + L G + C + G W
Sbjct: 180 DIRNGRH------SGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWR--PSP 231
Query: 2616 PSCRVISC--GSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSE 2673
P+C I+C +S + G + Y T +F C G+ L GS V C A+ W+ S
Sbjct: 232 PTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSP 291
Query: 2674 TRCLAGHCGSPDPIVNGH-------ISGDGFSYRDTVVYQCNPGFRLV--GTSVRICLQD 2724
C C + I + D + + Y+C+PG++ + IC ++
Sbjct: 292 PACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKN 351
Query: 2725 HKWS---GQTPVCVP--------ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQG 2773
+W+ G +C P IT PA N + D ++F+C+
Sbjct: 352 LRWTPYQGCEALCCPEPKLNNGEITQHRKSRPA----NHCVYFYGDEISFSCHETSRFSA 407
Query: 2774 VSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFY 2833
+ C+ +G WS P+C + C+ P + + H +Q+ SF + I+Y C KG+
Sbjct: 408 I----CQGDGTWSPRTPSCGDI-CNFPPKIAHG--HYKQSSSYSF-FKEEIIYECDKGYI 459
Query: 2834 LLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLI 2893
L+G + L+C + W P+C A+ V + + + V C ++
Sbjct: 460 LVGQAKLSC-SYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVV 518
Query: 2894 GNDTRVCQEDSHWSGALPHCTGNNPGFC 2921
G + C + W +P C P C
Sbjct: 519 GPQSITCSGNRTWYPEVPKCEWETPEGC 546
Score = 104 bits (259), Expect = 2e-21
Identities = 139/576 (24%), Positives = 201/576 (34%), Gaps = 123/576 (21%)
Query: 2256 LKKCQPPP----AVPQAEMLTEDDDFEIGDFVKYQCHPGYTLV-GTDILTCKLSSQLQFE 2310
L C PPP A P LTE F+ G +KY C PGY T LTC + +
Sbjct: 47 LGNCGPPPTLSFAAPMDITLTETR-FKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVY- 104
Query: 2311 GSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
C R +PG N Q IK + +F S+
Sbjct: 105 ------NTFCIYKRCR-----------HPGELRNGQV---EIKTDL---------SFGSQ 135
Query: 2371 KQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
+F E F L G+ T + R + WS +
Sbjct: 136 IEFSCSEGF-----------FLIGSTTSRCEVQDRG----VGWS-------------HPL 167
Query: 2431 PYCSLTHPLKNGGILN-RTAG-----AVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQW 2484
P C + I N R +G A G V Y C P + ++GH++ +C + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 2485 DSLTPLCQAVSCGIPE-SPGN-GSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG 2542
P C+ ++C P+ S G S G + +V++C +GF L S + C D
Sbjct: 228 RPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGS--SVIHCDADS 285
Query: 2543 LWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE----YGAQVLLSCSPGY--YLE 2596
W+ PP C+P +C I H W E G + C PGY +
Sbjct: 286 KWN--PSPPACEPNSC--INLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTD 341
Query: 2597 GWRLLRCQANGTWNIGDERPSCRVISC-------GSL-----SFPPNGNKIGTLTVYGAT 2644
+ CQ N W C + C G + S P N + YG
Sbjct: 342 EPTTVICQKNLRWT---PYQGCEALCCPEPKLNNGEITQHRKSRPAN----HCVYFYGDE 394
Query: 2645 AIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHI--SGDGFSYRDT 2702
F+C+ C +G WS C C P I +GH S +++
Sbjct: 395 ISFSCHE----TSRFSAICQGDGTWSPRTPSC-GDICNFPPKIAHGHYKQSSSYSFFKEE 449
Query: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNG------SEFN 2756
++Y+C+ G+ LVG + C H WS P C + C P NG ++
Sbjct: 450 IIYECDKGYILVGQAKLSCSYSH-WSAPAPQCKAL-CRKP-----ELVNGRLSVDKDQYV 502
Query: 2757 LNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2792
+ V C++GY + G C N W +P C
Sbjct: 503 EPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 54.3 bits (129), Expect = 2e-06
Identities = 59/268 (22%), Positives = 98/268 (36%), Gaps = 47/268 (17%)
Query: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTCQ---HGINRNWNYPFP 2141
+ C P +NG + I +D S G + F C G+ LIG C+ G+ W++P P
Sbjct: 111 KRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV--GWSHPLP 168
Query: 2142 RCD-APCGYNVTSQNG------TIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQT 2194
+C+ C +NG Y+ GF Y + P + + +
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTY----------SCDPRFSL-LGHASISC 217
Query: 2195 EAVNDYIAVW-------DGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFF 2247
N+ I VW + P + + Y+ + ++ K F G
Sbjct: 218 TVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSS 277
Query: 2248 VLNFHAFQLKKCQPP----------PAVPQAE-----MLTEDDDFEIGDFVKYQCHPGYT 2292
V++ A PP P +P A T++D + +G ++Y+CHPGY
Sbjct: 278 VIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYK 337
Query: 2293 LVGTDILTCKLSSQLQFEGSLPTCEAQC 2320
+ T L++ CEA C
Sbjct: 338 PTTDEPTTVICQKNLRWT-PYQGCEALC 364
Score = 50.8 bits (120), Expect = 2e-05
Identities = 61/285 (21%), Positives = 83/285 (29%), Gaps = 77/285 (27%)
Query: 349 CPDPGIPENGRRAGSD-FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPIC 407
C P NGR +G + F G +V +SC+ + L G SI+C ET+ W P C
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Query: 408 RARTC------------------------------GSNLRG-------------PSGVIT 424
TC G LRG PS
Sbjct: 235 EKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPAC 294
Query: 425 SPNYPVQYEDNAHCVWVI--TTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVL 482
PN + D H W T D + + GY T
Sbjct: 295 EPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTT-------------- 340
Query: 483 YVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGS 542
P ++ N W Q +++ P K EI + P
Sbjct: 341 ------DEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPA-------NHC 387
Query: 543 SFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFF 587
+ +GD ++F C CQ + WS PSC C F
Sbjct: 388 VYFYGDEISFSCHETSRFSA----ICQGDGTWSPRTPSCGDICNF 428
Score = 47.0 bits (110), Expect = 3e-04
Identities = 59/262 (22%), Positives = 101/262 (38%), Gaps = 46/262 (17%)
Query: 1916 CQEPALPSNSIK--IGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIA 1973
C++P + + G Y D + F+C+ G+ L+G S I C + +WN P C
Sbjct: 239 CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADS--KWNPSPPAC-- 294
Query: 1974 TCGGTLSTLGGVILSPGFP----GSYPN-NLDCTWRISLPIGYGAHIQFLNFSTEANHDF 2028
I P P +YP + + + + Y H + + E
Sbjct: 295 -------EPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVI 347
Query: 2029 LE--IQNGPYHTSPMI----GQFSGTDLPAALLSTTHETLIHFYSD------HSQNRQGF 2076
+ ++ PY + + + ++ S ++FY D H +R F
Sbjct: 348 CQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSR--F 405
Query: 2077 KLAYQ-----AYELQNCPD----PPPFQNG-YMINSDYS-VGQSVSFECYPGYILIGHPV 2125
Q + +C D PP +G Y +S YS + + +EC GYIL+G
Sbjct: 406 SAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAK 465
Query: 2126 LTCQHGINRNWNYPFPRCDAPC 2147
L+C + +W+ P P+C A C
Sbjct: 466 LSCSYS---HWSAPAPQCKALC 484
Score = 46.2 bits (108), Expect = 6e-04
Identities = 48/247 (19%), Positives = 89/247 (36%), Gaps = 77/247 (31%)
Query: 1565 CFDPGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
C PG + NG + TD GS I + C G+ ++ ++ C + D W LP C
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEV-QDRGVGWSHPLPQCE 171
Query: 1624 -APC-------GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTAL 1675
C G+++G E Y + ++ C F + G
Sbjct: 172 IVKCKPPPDIRNGRHSGEENF-----YAYGFSVTYSC------DPRFSLLGH-------- 212
Query: 1676 NDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVP 1735
+S+S + ET+ + ++ P
Sbjct: 213 -----------------ASISCTVENETIGV------------------------WRPSP 231
Query: 1736 RTSDTQCSSVPEPRYGRRI---GSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQW 1792
T + P+ +G + G ++ + F+C G++L+GS+ +HC +A ++W
Sbjct: 232 PTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHC----DADSKW 287
Query: 1793 NDTIPSC 1799
N + P+C
Sbjct: 288 NPSPPAC 294
Score = 46.2 bits (108), Expect = 6e-04
Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 1392 CNDPGMPQNGTRYGDSR--EAGDTVTFQCDPGYQLQGQAKITCVQLNNRF-FWQPDPPTC 1448
C P +NG G+ G +VT+ CDP + L G A I+C N W+P PPTC
Sbjct: 175 CKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTC 234
Score = 40.4 bits (93), Expect = 0.032
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Query: 690 YTTFG-QNECHDPGIPINGR-RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVV 747
Y TF C PG NG+ GS + F C +GF GS + C +QD V
Sbjct: 104 YNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLI-GSTTSRCEVQDRGVG 162
Query: 748 WSSTVPRCE 756
WS +P+CE
Sbjct: 163 WSHPLPQCE 171
Score = 38.9 bits (89), Expect = 0.092
Identities = 56/253 (22%), Positives = 91/253 (35%), Gaps = 28/253 (11%)
Query: 1064 VGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLS--PNF 1121
VG L + C GY+ T + W+ P C A C K N G + +
Sbjct: 324 VGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNGEITQHRKSR 382
Query: 1122 PSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLG 1181
P+N+ C+Y E H +R + +GD + + S + F G
Sbjct: 383 PANH-----CVYFYGDEISFSCHETSRFSAICQGDG--TWSPRTPSCGDICNFPPKIAHG 435
Query: 1182 LILNSTSNHLWLEFNTNGSDTDQGFQL--------TYTSFDL------VKCEDPGIPNYG 1227
S+S + E + D+G+ L +Y+ + C P + N
Sbjct: 436 HYKQSSSYSFFKEEIIY--ECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGR 493
Query: 1228 YRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATS 1287
+ + + V C+ GY + G ++TC SG+ R W +P C E +
Sbjct: 494 LSVDKDQYVEPENVTIQCDSGYGVVGPQSITC-SGN-RTWYPEVPKCEWETPEGCEQVLT 551
Query: 1288 GRILSPGYPAPYD 1300
G+ L P P D
Sbjct: 552 GKRLMQCLPNPED 564
Score = 37.7 bits (86), Expect = 0.21
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 1741 QCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
+C E R G+ I ++ S GS + F C+ G+ L GST C+ V + W+ +P C
Sbjct: 112 RCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCE-VQDRGVGWSHPLPQC 170
Query: 1800 -VVPC 1803
+V C
Sbjct: 171 EIVKC 175
Score = 37.7 bits (86), Expect = 0.21
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 4/36 (11%)
Query: 1587 ITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
+T QCDSGY ++ P SITC G +W +P C
Sbjct: 507 VTIQCDSGYGVVGPQSITC----SGNRTWYPEVPKC 538
Score = 37.4 bits (85), Expect = 0.27
Identities = 57/279 (20%), Positives = 89/279 (31%), Gaps = 62/279 (22%)
Query: 2092 PPFQNGYMINSD---YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCG 2148
P +G M++ Y+ ++ F+C G++L G V+ C + WN P C+
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCD--ADSKWNPSPPACEP--- 296
Query: 2149 YNVTSQNGTIYSPGFP----DEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVW 2204
N I P P + YP P VY+ T+L+ Y
Sbjct: 297 ------NSCINLPDIPHASWETYPR----------PTKEDVYVVGTVLRYRCHPGYKPTT 340
Query: 2205 DGPD----QNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFV------LNFHAF 2254
D P Q + + + G AL N + H V ++F
Sbjct: 341 DEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCH 400
Query: 2255 QLKK---------------------CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTL 2293
+ + C PP + + + Y+C GY L
Sbjct: 401 ETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYIL 460
Query: 2294 VGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGV 2332
VG L+C S + P C+A C E+ G V
Sbjct: 461 VGQAKLSCSYS---HWSAPAPQCKALCRKPELVNGRLSV 496
Score = 37.0 bits (84), Expect = 0.35
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 2084 ELQNCPDPPPFQNGYMINSD--YSVGQSVSFECYPGYILIGHPVLTC 2128
E+ C PP +NG + Y+ G SV++ C P + L+GH ++C
Sbjct: 171 EIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISC 217
Score = 36.6 bits (83), Expect = 0.46
Identities = 47/219 (21%), Positives = 75/219 (34%), Gaps = 63/219 (28%)
Query: 892 IRSTVTFSCDPGYTLSDDEP--LVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPD 949
+ + + + C PGY + DEP ++C++N +W C+ALC + +G
Sbjct: 324 VGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEPKLNNG--------- 373
Query: 950 FYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTI 1009
E++ + + H + E FS + + G+ P T
Sbjct: 374 ------------EITQHRKSRPANHCVYFYGDEISFSCHETSRFS-AICQGDGTWSPRTP 420
Query: 1010 KAGLFGNFTAQL---RFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGD 1066
G NF ++ + S S+ F E + CD
Sbjct: 421 SCGDICNFPPKIAHGHYKQSSSYSF------FKEEIIYECDK------------------ 456
Query: 1067 SLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAEC 1105
GY L G KL+C WSAP P+C A C
Sbjct: 457 --------GYILVGQAKLSC---SYSHWSAPAPQCKALC 484
Score = 36.2 bits (82), Expect = 0.60
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 698 CHDPGIPINGRRFGDR--FLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRC 755
C P + +NGR D+ ++ +V+ CD G+ G +SITC GN W VP+C
Sbjct: 484 CRKPEL-VNGRLSVDKDQYVEPENVTIQCDSGY-GVVGPQSITC---SGNRTWYPEVPKC 538
Query: 756 E 756
E
Sbjct: 539 E 539
Score = 35.8 bits (81), Expect = 0.78
Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 6/65 (9%)
Query: 868 TLESDSCLDPGIP----VNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHA 923
T E +C P + V+G G + + T+ F C G+ L + C+ + +WN +
Sbjct: 233 TCEKITCRKPDVSHGEMVSGF--GPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPS 290
Query: 924 LPSCD 928
P+C+
Sbjct: 291 PPACE 295
Score = 35.8 bits (81), Expect = 0.78
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 22/113 (19%)
Query: 872 DSCLDPGIPVNGH-RHGGDFGI-RSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDA 929
D C P +GH + + + + + CD GY L L C +H W+ P C A
Sbjct: 424 DICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH-WSAPAPQCKA 482
Query: 930 LC--------------GGYIQGKSGTV-LSPGFPDFYPNSLNC----TWTIEV 963
LC Y++ ++ T+ G+ P S+ C TW EV
Sbjct: 483 LCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEV 535
Score = 35.4 bits (80), Expect = 1.0
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 1391 TCNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
TC P + + +G DT+ F+C G+ L+G + I C + W P PP C
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSK---WNPSPPAC 294
Score = 35.0 bits (79), Expect = 1.3
Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C PG NG+ G+ ++FSC + + L GS + C+ V + WS P C
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCE-VQDRGVGWSHPLPQCE 171
Query: 409 ARTC 412
C
Sbjct: 172 IVKC 175
Score = 35.0 bits (79), Expect = 1.3
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
Query: 1412 DTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAAC 1452
+ + ++CD GY L GQAK++C + W P C A C
Sbjct: 448 EEIIYECDKGYILVGQAKLSC----SYSHWSAPAPQCKALC 484
Score = 34.7 bits (78), Expect = 1.7
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 165 DKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
++I Y C GYIL G A L+C S W PAP C+A
Sbjct: 448 EEIIYECDKGYILVGQAKLSCSYS-----HWSAPAPQCKA 482
Score = 34.3 bits (77), Expect = 2.3
Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 1001 TGSVLPHTIKAGLFGNFTAQ-LRFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSR-RI 1058
TG+ L +T G + + Q L SD Y F I + C PG + I
Sbjct: 73 TGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCI------YKRCRHPGELRNGQVEI 126
Query: 1059 GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRV-WSAPLPRC-VAEC 1105
G + FSC G+ L G+T C R V WS PLP+C + +C
Sbjct: 127 KTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKC 175
Score = 33.9 bits (76), Expect = 3.0
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Query: 1412 DTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
+ VT QCD GY + G ITC + W P+ P C
Sbjct: 505 ENVTIQCDSGYGVVGPQSITC---SGNRTWYPEVPKC 538
Score = 32.7 bits (73), Expect = 6.6
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 544 FLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
++ + +T +C + + +VG + ITC N W P C
Sbjct: 501 YVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 32.3 bits (72), Expect = 8.6
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 874 CLDPGIPVNGHRH-GGDFGIRSTVTFSCDPGYTLSDDEPLVCE---RNHQWNHALPSCD 928
C PG NG D S + FSC G+ L CE R W+H LP C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCE 171
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 129 bits (323), Expect = 7e-29
Identities = 118/444 (26%), Positives = 182/444 (40%), Gaps = 43/444 (9%)
Query: 2676 CLAGHCGSPDP-----IVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQ 2730
C+A C P I+ G S + +Y+C PG+R +G + +C + +W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVAL 74
Query: 2731 TPV--CVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQG-VSRAQCRSNGQ 2784
P+ C CGHPG+ G T G+ F +TCN GY L G ++ +C ++G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 2785 WSSPLPTCRVVNCSDPGFVENA-IRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCM 2843
W++ +P C VV C EN I + +G ++ + C G+ + G + C
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 2844 ANGLWDRSLPKCLAISCGHPGVPANAVLTGE-LFTYGAVVHYSCRGSESLIGNDTRVCQE 2902
+G W + PKC+ ISC P V + ++ + ++ Y C VC E
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 2903 DSHWSGALPHCTGNNPGFCGDPGTP-AHGSRLGDDFKTKSLLRFSCEMGH--QLRGSPER 2959
S W LP C + C +P P S L +T + + C G RG+ +
Sbjct: 254 -SGWR-PLPSCEEKS---CDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK 308
Query: 2960 TCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSS-----DGILFSSSVIYACWEGYKT-S 3013
C G W P C C P G+ + + Y C E ++T S
Sbjct: 309 -CTSTG-WIP-APRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPS 365
Query: 3014 GLMTR--HCTANGTWTGTAPDCTIISCGDPGTLANGI--QFGTDFTFNKTVSYQCNPGYV 3069
G HCT +G W+ P + C P L NG G F K++ C+PGY
Sbjct: 366 GSYWDHIHCTQDG-WSPAVP--CLRKCYFP-YLENGYNQNHGRKFVQGKSIDVACHPGYA 421
Query: 3070 MEAVTSATIRCTKDGRWNPSKPVC 3093
+ T+ C ++G W+P+ P C
Sbjct: 422 LPK-AQTTVTCMENG-WSPT-PRC 442
Score = 118 bits (295), Expect = 1e-25
Identities = 121/427 (28%), Positives = 174/427 (40%), Gaps = 45/427 (10%)
Query: 2453 GSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPL--CQAVSCGIPESPGNGSFT-- 2508
G++ Y C+PGYR +G+ CR+ +W +L PL CQ CG P G+FT
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVCRKG-----EWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 2509 -GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSE 2567
GN F K VY C+EG++L + C DG W+N P C+ V C + A +
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQL-LGEINYRECDTDG-WTN--DIPICEVVKCLPVTAPENG 155
Query: 2568 HVIWRLVSGSLN-EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSL 2626
++ + +G V C+ GY +EG + C +G W+ E+P C ISC S
Sbjct: 156 KIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWS--KEKPKCVEISCKSP 213
Query: 2627 SFPPNGNKIGTLTVYGATAIF--TCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSP 2684
NG+ I +Y F CN GY C +G W + C C +P
Sbjct: 214 DV-INGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLPS-CEEKSCDNP 270
Query: 2685 DPIVNGHISGDGFSYR--DTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
I NG S +R D + YQC GF W P C C +P
Sbjct: 271 -YIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI-PAPRCTLKPCDYP 328
Query: 2743 GNPAHGFTNGS------EFNLNDVVNFTCNTGYLLQGVS---RAQCRSNGQWSSPLPTCR 2793
G + + + ++ C+ + S C +G WS +P R
Sbjct: 329 DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPCLR 387
Query: 2794 VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYL-LGSSALTCMANGLWDRSL 2852
C P ++EN QN F G SI C G+ L + +TCM NG W +
Sbjct: 388 --KCYFP-YLENGY---NQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPT- 439
Query: 2853 PKCLAIS 2859
P+C+ +S
Sbjct: 440 PRCIRVS 446
Score = 116 bits (290), Expect = 5e-25
Identities = 129/447 (28%), Positives = 173/447 (38%), Gaps = 61/447 (13%)
Query: 2855 CLAISCGH-PGVPANAVLTG----ELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGA 2909
C+A C P +LTG + + G Y CR +GN VC++ W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVAL 74
Query: 2910 LP--HCTGNNPGFCGDPGTPAHGSRL---GDDFKTKSLLRFSCEMGHQLRGSPE-RTCLL 2963
P C CG PG G+ G+ F+ ++C G+QL G R C
Sbjct: 75 NPLRKCQKRP---CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT 131
Query: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSD-----GILFSSSVIYACWEGYKTSGLMTR 3018
+G W+ P+CE V C P NG IVSS F +V + C GYK G
Sbjct: 132 DG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEM 190
Query: 3019 HCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTF--NKTVSYQCNPGYVMEAVTSA 3076
HC+ +G W+ P C ISC P + NG + N+ Y+CN GY A
Sbjct: 191 HCSDDGFWSKEKPKCVEISCKSPDVI-NGSPISQKIIYKENERFQYKCNMGYEYSERGDA 249
Query: 3077 TIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE--GSDFRWGSSISYSCMDG-YQLSHS 3133
CT+ G W P P C+ C P + NG R G I+Y C +G Y +
Sbjct: 250 V--CTESG-WRP-LPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRG 304
Query: 3134 AILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLS------------GKSFTYKSEVFFQ 3181
C G W P+C C P I G GK ++Y + F+
Sbjct: 305 NTAKCTSTG-WI-PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFE 362
Query: 3182 CKSPFILVGS--SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGST 3239
S GS C DG WS P C+ C P + QN R + G +
Sbjct: 363 TPS-----GSYWDHIHCTQDG-WSPAVP-CL----RKCYFPYLENGYNQNHGRKFVQGKS 411
Query: 3240 VFFRCRKGYHI-QGSTTRTCLANLTWS 3265
+ C GY + + TT TC+ N WS
Sbjct: 412 IDVACHPGYALPKAQTTVTCMEN-GWS 437
Score = 111 bits (278), Expect = 1e-23
Identities = 117/464 (25%), Positives = 176/464 (37%), Gaps = 71/464 (15%)
Query: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIG 2612
C C + + + ++ S G Q + C PGY G ++ C+ G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 2613 DERPSCRVISCGSLSFPPNGNKIGTLTV-------YGATAIFTCNTGYTLVGS-HVRECL 2664
+ C+ CG P GT T+ YG A++TCN GY L+G + REC
Sbjct: 75 NPLRKCQKRPCGH----PGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECD 130
Query: 2665 ANGLWSGSETRCLAGHCGSPDPIVNGHISGDG------FSYRDTVVYQCNPGFRLVGTSV 2718
+G W+ C C NG I + + V + CN G+++ G
Sbjct: 131 TDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEE 189
Query: 2719 RICLQDHKWSGQTPVCVPITCGHP----GNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV 2774
C D WS + P CV I+C P G+P + + N+ + CN GY
Sbjct: 190 MHCSDDGFWSKEKPKCVEISCKSPDVINGSP---ISQKIIYKENERFQYKCNMGYEYSER 246
Query: 2775 SRAQCRSNGQWSSPLPTCRVVNCSDPGFVENA------IRHGQQNFPESFEYGMSILYHC 2828
A C +G W PLP+C +C +P ++ N I+H G I Y C
Sbjct: 247 GDAVCTESG-W-RPLPSCEEKSCDNP-YIPNGDYSPLRIKH---------RTGDEITYQC 294
Query: 2829 KKGFY-LLGSSALTCMANGLWDRSLPKCLAISCGHPGV------------PANAVLTGEL 2875
+ GFY + C + G W + P+C C +P + P V G+
Sbjct: 295 RNGFYPATRGNTAKCTSTG-WIPA-PRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKY 352
Query: 2876 FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGD 2935
++Y H+ D C +D WS A+P + + HG +
Sbjct: 353 YSYYCDEHFETPSGSYW---DHIHCTQDG-WSPAVPCLRKCYFPYLENGYNQNHGRK--- 405
Query: 2936 DFKTKSLLRFSCEMGHQL-RGSPERTCLLNGSWSGLQPVCEAVS 2978
F + +C G+ L + TC+ NG WS P C VS
Sbjct: 406 -FVQGKSIDVACHPGYALPKAQTTVTCMENG-WSP-TPRCIRVS 446
Score = 106 bits (265), Expect = 4e-22
Identities = 105/428 (24%), Positives = 169/428 (39%), Gaps = 39/428 (9%)
Query: 2505 GSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQ 2564
GS++ + ++ +Y+C G++ S VC++ G W C+ C
Sbjct: 35 GSWSDQTYPEGTQAIYKCRPGYR--SLGNVIMVCRK-GEWVALNPLRKCQKRPCG--HPG 89
Query: 2565 LSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLR-CQANGTWNIGDERPSCRVISC 2623
+ + L G++ EYG + + +C+ GY L G R C +G N + P C V+ C
Sbjct: 90 DTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTN---DIPICEVVKC 146
Query: 2624 GSLSFPPNGNKIGTLTV------YGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCL 2677
++ P NG + + +G F CN+GY + G C +G WS + +C+
Sbjct: 147 LPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCV 206
Query: 2678 AGHCGSPDPIVNGHISGDGFSYRDT--VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCV 2735
C SPD ++NG Y++ Y+CN G+ +C + W P C
Sbjct: 207 EISCKSPD-VINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES-GWR-PLPSCE 263
Query: 2736 PITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNTG-YLLQGVSRAQCRSNGQWSSPLPTCR 2793
+C +P P ++ + D + + C G Y + A+C S G W P P C
Sbjct: 264 EKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W-IPAPRCT 321
Query: 2794 VVNCSDPGFVENAIRHGQQNFPE-SFEYGMSILYHCKKGFYLLGSS---ALTCMANGLWD 2849
+ C P + H P G Y+C + F S + C +G W
Sbjct: 322 LKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WS 380
Query: 2850 RSLPKCLAISCGHP----GVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSH 2905
++P CL C P G N G F G + +C +L T V ++
Sbjct: 381 PAVP-CLR-KCYFPYLENGYNQN---HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG 435
Query: 2906 WSGALPHC 2913
WS P C
Sbjct: 436 WS-PTPRC 442
Score = 104 bits (259), Expect = 2e-21
Identities = 98/408 (24%), Positives = 154/408 (37%), Gaps = 60/408 (14%)
Query: 2945 FSCEMGHQLRGSPERTCLLNGSWSGLQPV--CEAVSCGNPGTPTNGMIVSSDGILFSSSV 3002
+ C G++ G+ C G W L P+ C+ CG+PG G + G +F V
Sbjct: 50 YKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGV 108
Query: 3003 --IYACWEGYKTSGLMT-RHCTANGTWTGTAPDCTIISCGDPGTLANG------IQFGTD 3053
+Y C EGY+ G + R C +G WT P C ++ C NG ++ +
Sbjct: 109 KAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDRE 167
Query: 3054 FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSD 3113
+ F + V + CN GY +E + C+ DG W+ KP C + C P + +
Sbjct: 168 YHFGQAVRFVCNSGYKIEG--DEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKI 225
Query: 3114 -FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSF 3172
++ Y C GY+ S C G W+ +P C C +P IP G S
Sbjct: 226 IYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNPYIP-NGDYSPLRI 282
Query: 3173 TYKS--EVFFQCKSPFI-LVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGI-- 3227
+++ E+ +QC++ F + C + G W + P C P H G+
Sbjct: 283 KHRTGDEITYQCRNGFYPATRGNTAKCTSTG-WIPAPRCTLKP----CDYPDIKHGGLYH 337
Query: 3228 QNSSRGY---EVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAH 3284
+N R Y VG + C + + + W I H + +PA
Sbjct: 338 ENMRRPYFPVAVGKYYSYYCDEHFETPSGSY--------WDHI------HCTQDGWSPAV 383
Query: 3285 ADVRAIDLPTF--------------GYTLVYTCHPGFFLAGGSEHRTC 3318
+R P G ++ CHPG+ L TC
Sbjct: 384 PCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTC 431
Score = 75.9 bits (185), Expect = 7e-13
Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 15/229 (6%)
Query: 3092 VCKAVLCPQPPPVQN-----GTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKG 3146
+C A C + PP +N G+ + G+ Y C GY+ + I+ C +G W
Sbjct: 15 ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVA 73
Query: 3147 EIP--QCLPVFCGDPGIPAEGRLS---GKSFTYKSEVFFQCKSPFILVGS-SRRVCQADG 3200
P +C CG PG G + G F Y + + C + L+G + R C DG
Sbjct: 74 LNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG 133
Query: 3201 TWSGIQPTC--IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC 3258
W+ P C + T P+ G R Y G V F C GY I+G C
Sbjct: 134 -WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC 192
Query: 3259 LANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGF 3307
+ WS + +C+ +C+ P+ + + + Y C+ G+
Sbjct: 193 SDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGY 241
Score = 48.1 bits (113), Expect = 2e-04
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 6/107 (5%)
Query: 3230 SSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQT--ECIPHACRQP-ETPAHA- 3285
S + Y G+ ++CR GY G+ C W + +C C P +TP
Sbjct: 38 SDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWVALNPLRKCQKRPCGHPGDTPFGTF 96
Query: 3286 DVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
+ ++ +G VYTC+ G+ L G +R C D WT P+C+
Sbjct: 97 TLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-GWTNDIPICE 142
Score = 41.2 bits (95), Expect = 0.019
Identities = 82/381 (21%), Positives = 139/381 (36%), Gaps = 51/381 (13%)
Query: 2256 LKKCQPPPAVPQAEM------LTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQF 2309
L+KCQ P + LT + FE G Y C+ GY L+G + + +
Sbjct: 77 LRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGE--INYRECDTDGW 134
Query: 2310 EGSLPTCE-AQC-PANEVRTG---SSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV 2364
+P CE +C P G SS + Y C+ K+E + +
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 2365 DTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGF 2424
D F S+++ +E+ S +SP V++G+ Q + + + + + S++G
Sbjct: 195 DGFWSKEKPKCVEI----SCKSP--DVINGSPISQKIIYKENERFQYKCNMGYEYSERGD 248
Query: 2425 KIRYAA-----PYC---SLTHPLKNGGILN--RTAGAVGSKVHYFCKPGYRMVGHSNATC 2474
+ + P C S +P G + R G ++ Y C+ G+ N T
Sbjct: 249 AVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGN-TA 307
Query: 2475 RRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGN------EFTLDSKVVYECHEGFKL 2528
+ G P C C P+ G + N + Y C E F+
Sbjct: 308 KCTSTGWIP----APRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFET 363
Query: 2529 ESSQQATAV-CQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLL 2587
S + C +DG WS P + P +E +++ + V G + +
Sbjct: 364 PSGSYWDHIHCTQDG-WS--PAVPCLRKCYFPYLENGYNQNHGRKFVQGK------SIDV 414
Query: 2588 SCSPGYYL-EGWRLLRCQANG 2607
+C PGY L + + C NG
Sbjct: 415 ACHPGYALPKAQTTVTCMENG 435
Score = 40.4 bits (93), Expect = 0.032
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 10/73 (13%)
Query: 1734 VPRTSDTQCSSVPEPRYGRRIGS------EFSAGSIVRFECNPGYLLQGSTALHCQSVPN 1787
+P +C V P G+ + S E+ G VRF CN GY ++G +HC
Sbjct: 138 IPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDD-- 195
Query: 1788 ALAQWNDTIPSCV 1800
W+ P CV
Sbjct: 196 --GFWSKEKPKCV 206
Score = 36.2 bits (82), Expect = 0.60
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 2086 QNCPDPPPFQN-----GYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPF 2140
++C + PP +N G + Y G ++C PGY +G+ ++ C+ G N P
Sbjct: 19 EDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALN-PL 77
Query: 2141 PRCD-APCGYNVTSQNGTIYSPG 2162
+C PCG+ + GT G
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTG 100
Score = 33.9 bits (76), Expect = 3.0
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 1194 EFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRD------EGHFTDTVVLYSCNP 1247
E N DTD G+ ++VKC P G + E HF V + CN
Sbjct: 123 EINYRECDTD-GWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAV-RFVCNS 180
Query: 1248 GYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
GY + G + C D W K P C+
Sbjct: 181 GYKIEGDEEMHC--SDDGFWSKEKPKCV 206
Score = 33.5 bits (75), Expect = 3.9
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Query: 1398 PQNGTRYGDSREA------GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI 1449
P+NG + E G V F C+ GY+++G ++ C ++ FW + P C+
Sbjct: 152 PENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHC---SDDGFWSKEKPKCV 206
Score = 33.5 bits (75), Expect = 3.9
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 1060 FHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
+HFG ++ F C GY++EG ++ C G WS P+CV
Sbjct: 168 YHFG--QAVRFVCNSGYKIEGDEEMHCSDDG--FWSKEKPKCV 206
Score = 32.7 bits (73), Expect = 6.6
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 521 QEIEKGGCGDPGIPAYGKRT---GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGN 577
++ +K CG PG +G T G+ F +G + C ++L+GE + W+ +
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTND 137
Query: 578 KPSC-VFSCFFNFTASSGIILS 598
P C V C +G I+S
Sbjct: 138 IPICEVVKCLPVTAPENGKIVS 159
Score = 32.7 bits (73), Expect = 6.6
Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 547 GDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV-FSC 585
G + F C + +++ G+ + C + WS KP CV SC
Sbjct: 171 GQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISC 210
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 123 bits (308), Expect = 4e-27
Identities = 66/183 (36%), Positives = 93/183 (50%), Gaps = 7/183 (3%)
Query: 2647 FTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVV 2704
+ C GY LVG C A+ W + T C GHC PDP+ VNG S G + D +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 104
Query: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFT 2764
+ CN + L G++ CL+DH W+ P+C C PGNP HG+ G+ F L +++
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 2765 CNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGM 2822
C Y L GV QC +G+WSS LP C+++ + E A+ Q+ N E+ E M
Sbjct: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFM 223
Query: 2823 SIL 2825
L
Sbjct: 224 QQL 226
Score = 83.6 bits (205), Expect = 3e-15
Identities = 48/157 (30%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 2826 YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAV---- 2881
Y C KG++L+G L C A+ WD + +C C P ++ GE + G V
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-----VLVNGEFSSSGPVNVSD 101
Query: 2882 -VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
+ + C L G++ C ED W+ P C + C PG P HG G++F
Sbjct: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD---CDPPGNPVHGYFEGNNFTLG 158
Query: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2977
S + + CE + L G E+ C ++G WS PVC+ +
Sbjct: 159 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 79.3 bits (194), Expect = 6e-14
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 2763 FTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGM 2822
+ C GY L G C ++ +W + CR+ +C DP V +G+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-----NGEFSSSGPVNVSD 101
Query: 2823 SILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVV 2882
I + C + L GS+ C+ + W P C + C PG P + G FT G+ +
Sbjct: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
Query: 2883 HYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913
Y C L+G + C D WS ALP C
Sbjct: 162 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Score = 75.1 bits (183), Expect = 1e-12
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 5/158 (3%)
Query: 2945 FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
+ C G+ L G C + W C C +P NG SS + S + +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
Query: 3005 ACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQC 3064
C + Y G C + TW P C C PG +G G +FT T+SY C
Sbjct: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
Query: 3065 NPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQP 3101
Y + V +C DG W+ + PVCK + P+P
Sbjct: 166 EDRYYLVGVQEQ--QCV-DGEWSSALPVCKLIQEAPKP 200
Score = 74.7 bits (182), Expect = 2e-12
Identities = 50/190 (26%), Positives = 68/190 (35%), Gaps = 5/190 (2%)
Query: 3020 CTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIR 3079
C W +A D C + + N I + +Y C GY + V T+
Sbjct: 7 CCLMVAWRVSASDAE--HCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL--VGKKTLF 62
Query: 3080 CTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCE 3139
C W+ + C+ CP P V I++ C D Y L S C
Sbjct: 63 CNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 122
Query: 3140 GRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD 3199
W P C C PG P G G +FT S + + C+ + LVG + C D
Sbjct: 123 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VD 181
Query: 3200 GTWSGIQPTC 3209
G WS P C
Sbjct: 182 GEWSSALPVC 191
Score = 67.4 bits (163), Expect = 2e-10
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 5/153 (3%)
Query: 2884 YSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLL 2943
Y C L+G T C W C G C DP +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 2944 RFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVI 3003
F C + L+GS CL + +W+ P+C++ C PG P +G + S++
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYF-EGNNFTLGSTIS 162
Query: 3004 YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 3036
Y C + Y G+ + C +G W+ P C +I
Sbjct: 163 YYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 66.2 bits (160), Expect = 5e-10
Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 3180 FQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGST 3239
+ C + LVG C A W C CPDP + G +SS V
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSDK 102
Query: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTL 3299
+ F C Y ++GS CL + TW+ C C P P H + T G T+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGSTI 161
Query: 3300 VYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Y C ++L G E + D +W+ PVCK
Sbjct: 162 SYYCEDRYYLVGVQEQQC--VDGEWSSALPVCK 192
Score = 58.5 bits (140), Expect = 1e-07
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 2433 CSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
C L H L NG + V K+ + C Y + G + + C + + W
Sbjct: 76 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 131
Query: 2489 PLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKG 2548
P+C++ C P +P +G F GN FTL S + Y C + + L Q+ V DG WS+
Sbjct: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGEWSS-- 186
Query: 2549 KPPTCK 2554
P CK
Sbjct: 187 ALPVCK 192
Score = 51.2 bits (121), Expect = 2e-05
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 2458 YFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGN-EFTLDS 2516
Y C GY +VG C + +WD+ T C+ C P NG F+ + +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASK----EWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSD 101
Query: 2517 KVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSG 2576
K+ + C++ + L+ S ++ C ED W+ PP P+ C S + + + G
Sbjct: 102 KITFMCNDHYILKGSNRSQ--CLEDHTWA----PPF--PI-CKSRDCDPPGNPVHGYFEG 152
Query: 2577 SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI 2621
+ G+ + C YYL G + +C +G W+ P C++I
Sbjct: 153 NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS--SALPVCKLI 194
Score = 48.1 bits (113), Expect = 2e-04
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 3244 CRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQP-----ETPAHADVRAIDLPTFGYT 3298
C KGYH+ G T C A+ W TEC C P E + V D TF
Sbjct: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF--- 105
Query: 3299 LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSK 3334
C+ + L GS C D W P+CKS+
Sbjct: 106 ---MCNDHYILK-GSNRSQCLEDHTWAPPFPICKSR 137
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 20/183 (10%)
Query: 2499 PESP--GNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPV 2556
PE P N F E Y C +G+ L + T C W N C+
Sbjct: 24 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKK--TLFCNASKEWDNT--TTECRLG 79
Query: 2557 ACPS---IEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD 2613
CP + + S SG +N ++ C+ Y L+G +C + TW
Sbjct: 80 HCPDPVLVNGEFSS-------SGPVN-VSDKITFMCNDHYILKGSNRSQCLEDHTW--AP 129
Query: 2614 ERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSE 2673
P C+ C P +G G G+T + C Y LVG ++C+ +G WS +
Sbjct: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSAL 188
Query: 2674 TRC 2676
C
Sbjct: 189 PVC 191
Score = 44.7 bits (104), Expect = 0.002
Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 5/60 (8%)
Query: 697 ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE 756
+C PG P++G G+ F LGS++S++C+D + G + C+ DG WSS +P C+
Sbjct: 138 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVCK 192
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
C PGN ++G G +F LGSTI+Y C+ Y ++ CV G W LP C
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-----EWSSALPVC 191
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
CPDP + NG + S V + F C D+Y+L+GS C W+ PIC+
Sbjct: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPFPICK 135
Query: 409 ARTC 412
+R C
Sbjct: 136 SRDC 139
Score = 41.6 bits (96), Expect = 0.014
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 870 ESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
+S C PG PV+G+ G +F + ST+++ C+ Y L + C + +W+ ALP C
Sbjct: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
Score = 38.1 bits (87), Expect = 0.16
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C PG P +G G++F+ +G+ + + CED Y L G + C WS P+C+
Sbjct: 139 CDPPGNPVHGYFEGNNFT-LGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCK 192
Score = 38.1 bits (87), Expect = 0.16
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
C PG P +G G++F G T+++ C + LVG + C + +WS P C
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Score = 36.6 bits (83), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 1046 CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
CD PG P G +F +G ++++ C Y L G + C+ G WS+ LP C
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
Score = 35.4 bits (80), Expect = 1.0
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
T T L C DP + N + + +D + + CN Y + GSN CL + W
Sbjct: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKIT-FMCNDHYILKGSNRSQCL--EDHTWA 128
Query: 1269 KPLPSCIA-EC---GGQIHAATSGRILSPGYPAPY 1299
P P C + +C G +H G + G Y
Sbjct: 129 PPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
Score = 35.4 bits (80), Expect = 1.0
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 5/67 (7%)
Query: 137 YEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+ + S C PG + G G F +G I Y C Y L G C+ W
Sbjct: 131 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWS 185
Query: 197 FPAPFCR 203
P C+
Sbjct: 186 SALPVCK 192
Score = 34.3 bits (77), Expect = 2.3
Identities = 16/59 (27%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 1913 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
L C +P L + V+D ++F C Y L+G + C+ W P P+C
Sbjct: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 134
Score = 33.9 bits (76), Expect = 3.0
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 2085 LQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
L +CPDP + + +V ++F C YIL G C + W PFP C
Sbjct: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 134
Score = 33.9 bits (76), Expect = 3.0
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C+ PG P +G G++ G T+++ C+ Y L G + CV W P C
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 191
Score = 32.7 bits (73), Expect = 6.6
Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 2082 AYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFP 2141
A + ++CP+ PP N + + ++ C GY L+G L C ++ W+
Sbjct: 17 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTT 74
Query: 2142 RC 2143
C
Sbjct: 75 EC 76
Score = 32.7 bits (73), Expect = 6.6
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2086 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
++C P +GY +++++G ++S+ C Y L+G C G W+ P C
Sbjct: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
Score = 32.3 bits (72), Expect = 8.6
Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 874 CLDPGIPVNGH-RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-- 930
C DP + VNG G + +TF C+ Y L C +H W P C +
Sbjct: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDC 139
Query: 931 ------CGGYIQGKSGTV 942
GY +G + T+
Sbjct: 140 DPPGNPVHGYFEGNNFTL 157
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 123 bits (308), Expect = 4e-27
Identities = 66/183 (36%), Positives = 93/183 (50%), Gaps = 7/183 (3%)
Query: 2647 FTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVV 2704
+ C GY LVG C A+ W + T C GHC PDP+ VNG S G + D +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 103
Query: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFT 2764
+ CN + L G++ CL+DH W+ P+C C PGNP HG+ G+ F L +++
Sbjct: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
Query: 2765 CNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGM 2822
C Y L GV QC +G+WSS LP C+++ + E A+ Q+ N E+ E M
Sbjct: 164 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFM 222
Query: 2823 SIL 2825
L
Sbjct: 223 QQL 225
Score = 83.6 bits (205), Expect = 3e-15
Identities = 48/157 (30%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 2826 YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAV---- 2881
Y C KG++L+G L C A+ WD + +C C P ++ GE + G V
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-----VLVNGEFSSSGPVNVSD 100
Query: 2882 -VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
+ + C L G++ C ED W+ P C + C PG P HG G++F
Sbjct: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD---CDPPGNPVHGYFEGNNFTLG 157
Query: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2977
S + + CE + L G E+ C ++G WS PVC+ +
Sbjct: 158 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 79.3 bits (194), Expect = 6e-14
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 2763 FTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGM 2822
+ C GY L G C ++ +W + CR+ +C DP V +G+ +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-----NGEFSSSGPVNVSD 100
Query: 2823 SILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVV 2882
I + C + L GS+ C+ + W P C + C PG P + G FT G+ +
Sbjct: 101 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 160
Query: 2883 HYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913
Y C L+G + C D WS ALP C
Sbjct: 161 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Score = 77.0 bits (188), Expect = 3e-13
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 5/174 (2%)
Query: 3098 CPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCG 3157
CP+ PPV N + +Y C+ GY L L C W +C C
Sbjct: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
Query: 3158 DPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTC 3217
DP + S ++ F C +IL GS+R C D TW+ P C C
Sbjct: 82 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRDC 138
Query: 3218 PDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3271
PG P G + + +GST+ + C Y++ G + C+ WS C
Sbjct: 139 DPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 190
Score = 75.1 bits (183), Expect = 1e-12
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 5/158 (3%)
Query: 2945 FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
+ C G+ L G C + W C C +P NG SS + S + +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 104
Query: 3005 ACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQC 3064
C + Y G C + TW P C C PG +G G +FT T+SY C
Sbjct: 105 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 164
Query: 3065 NPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQP 3101
Y + V +C DG W+ + PVCK + P+P
Sbjct: 165 EDRYYLVGVQEQ--QCV-DGEWSSALPVCKLIQEAPKP 199
Score = 74.3 bits (181), Expect = 2e-12
Identities = 43/149 (28%), Positives = 57/149 (38%), Gaps = 3/149 (2%)
Query: 3061 SYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSI 3120
+Y C GY + V T+ C W+ + C+ CP P V I
Sbjct: 45 TYVCIKGYHL--VGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
Query: 3121 SYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFF 3180
++ C D Y L S C W P C C PG P G G +FT S + +
Sbjct: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
Query: 3181 QCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
C+ + LVG + C DG WS P C
Sbjct: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Score = 67.4 bits (163), Expect = 2e-10
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 5/153 (3%)
Query: 2884 YSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLL 2943
Y C L+G T C W C G C DP +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVNGEFSSSGPVNVSDKI 102
Query: 2944 RFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVI 3003
F C + L+GS CL + +W+ P+C++ C PG P +G + S++
Sbjct: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYF-EGNNFTLGSTIS 161
Query: 3004 YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 3036
Y C + Y G+ + C +G W+ P C +I
Sbjct: 162 YYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 66.2 bits (160), Expect = 5e-10
Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 3180 FQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGST 3239
+ C + LVG C A W C CPDP + G +SS V
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSDK 101
Query: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTL 3299
+ F C Y ++GS CL + TW+ C C P P H + T G T+
Sbjct: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGSTI 160
Query: 3300 VYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Y C ++L G E + D +W+ PVCK
Sbjct: 161 SYYCEDRYYLVGVQEQQC--VDGEWSSALPVCK 191
Score = 58.5 bits (140), Expect = 1e-07
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 2433 CSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
C L H L NG + V K+ + C Y + G + + C + + W
Sbjct: 75 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 130
Query: 2489 PLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKG 2548
P+C++ C P +P +G F GN FTL S + Y C + + L Q+ V DG WS+
Sbjct: 131 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGEWSS-- 185
Query: 2549 KPPTCK 2554
P CK
Sbjct: 186 ALPVCK 191
Score = 51.2 bits (121), Expect = 2e-05
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 2458 YFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGN-EFTLDS 2516
Y C GY +VG C + +WD+ T C+ C P NG F+ + +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASK----EWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSD 100
Query: 2517 KVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSG 2576
K+ + C++ + L+ S ++ C ED W+ PP P+ C S + + + G
Sbjct: 101 KITFMCNDHYILKGSNRSQ--CLEDHTWA----PPF--PI-CKSRDCDPPGNPVHGYFEG 151
Query: 2577 SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI 2621
+ G+ + C YYL G + +C +G W+ P C++I
Sbjct: 152 NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS--SALPVCKLI 193
Score = 48.1 bits (113), Expect = 2e-04
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 3244 CRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQP-----ETPAHADVRAIDLPTFGYT 3298
C KGYH+ G T C A+ W TEC C P E + V D TF
Sbjct: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF--- 104
Query: 3299 LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSK 3334
C+ + L GS C D W P+CKS+
Sbjct: 105 ---MCNDHYILK-GSNRSQCLEDHTWAPPFPICKSR 136
Score = 47.4 bits (111), Expect = 3e-04
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 20/183 (10%)
Query: 2499 PESP--GNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPV 2556
PE P N F E Y C +G+ L + T C W N C+
Sbjct: 23 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKK--TLFCNASKEWDNT--TTECRLG 78
Query: 2557 ACPS---IEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD 2613
CP + + S SG +N ++ C+ Y L+G +C + TW
Sbjct: 79 HCPDPVLVNGEFSS-------SGPVN-VSDKITFMCNDHYILKGSNRSQCLEDHTW--AP 128
Query: 2614 ERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSE 2673
P C+ C P +G G G+T + C Y LVG ++C+ +G WS +
Sbjct: 129 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSAL 187
Query: 2674 TRC 2676
C
Sbjct: 188 PVC 190
Score = 44.7 bits (104), Expect = 0.002
Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 5/60 (8%)
Query: 697 ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE 756
+C PG P++G G+ F LGS++S++C+D + G + C+ DG WSS +P C+
Sbjct: 137 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVCK 191
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
C PGN ++G G +F LGSTI+Y C+ Y ++ CV G W LP C
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-----EWSSALPVC 190
Score = 42.0 bits (97), Expect = 0.011
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
CPDP + NG + S V + F C D+Y+L+GS C W+ PIC+
Sbjct: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPFPICK 134
Query: 409 ARTC 412
+R C
Sbjct: 135 SRDC 138
Score = 41.6 bits (96), Expect = 0.014
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 870 ESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
+S C PG PV+G+ G +F + ST+++ C+ Y L + C + +W+ ALP C
Sbjct: 134 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 190
Score = 38.1 bits (87), Expect = 0.16
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
C PG P +G G++F+ +G+ + + CED Y L G + C WS P+C+
Sbjct: 138 CDPPGNPVHGYFEGNNFT-LGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCK 191
Score = 38.1 bits (87), Expect = 0.16
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
C PG P +G G++F G T+++ C + LVG + C + +WS P C
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
Score = 36.6 bits (83), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 1046 CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
CD PG P G +F +G ++++ C Y L G + C+ G WS+ LP C
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
Score = 35.4 bits (80), Expect = 1.0
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
T T L C DP + N + + +D + + CN Y + GSN CL + W
Sbjct: 71 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKIT-FMCNDHYILKGSNRSQCL--EDHTWA 127
Query: 1269 KPLPSCIA-EC---GGQIHAATSGRILSPGYPAPY 1299
P P C + +C G +H G + G Y
Sbjct: 128 PPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 162
Score = 35.4 bits (80), Expect = 1.0
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 5/67 (7%)
Query: 137 YEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
+ + S C PG + G G F +G I Y C Y L G C+ W
Sbjct: 130 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWS 184
Query: 197 FPAPFCR 203
P C+
Sbjct: 185 SALPVCK 191
Score = 34.3 bits (77), Expect = 2.3
Identities = 16/59 (27%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 1913 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
L C +P L + V+D ++F C Y L+G + C+ W P P+C
Sbjct: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 133
Score = 33.9 bits (76), Expect = 3.0
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 2085 LQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
L +CPDP + + +V ++F C YIL G C + W PFP C
Sbjct: 77 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 133
Score = 33.9 bits (76), Expect = 3.0
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
C+ PG P +G G++ G T+++ C+ Y L G + CV W P C
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 190
Score = 32.7 bits (73), Expect = 6.6
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2086 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
++C P +GY +++++G ++S+ C Y L+G C G W+ P C
Sbjct: 136 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 190
Score = 32.3 bits (72), Expect = 8.6
Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 874 CLDPGIPVNGH-RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-- 930
C DP + VNG G + +TF C+ Y L C +H W P C +
Sbjct: 80 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDC 138
Query: 931 ------CGGYIQGKSGTV 942
GY +G + T+
Sbjct: 139 DPPGNPVHGYFEGNNFTL 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 163,363,645
Number of Sequences: 37866
Number of extensions: 8509475
Number of successful extensions: 33115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 16380
Number of HSP's gapped (non-prelim): 6485
length of query: 3565
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3443
effective length of database: 13,627,866
effective search space: 46920742638
effective search space used: 46920742638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.