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Search of human proteins with 157502184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502184 kinesin family member 6 [Homo sapiens]
(814 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502184 kinesin family member 6 [Homo sapiens] 1602 0.0
gi|11641245 kinesin family member 9 isoform 1 [Homo sapiens] 340 2e-93
gi|199560800 kinesin family member 9 isoform 2 [Homo sapiens] 306 5e-83
gi|199560791 kinesin family member 9 isoform 2 [Homo sapiens] 306 5e-83
gi|46852174 kinesin family member 3A [Homo sapiens] 260 3e-69
gi|4758646 kinesin family member 3B [Homo sapiens] 243 4e-64
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 234 2e-61
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 234 2e-61
gi|9910266 kinesin family member 15 [Homo sapiens] 232 9e-61
gi|71061468 centromere protein E [Homo sapiens] 231 2e-60
gi|41352705 kinesin family member 3C [Homo sapiens] 226 7e-59
gi|45446749 kinesin family member 5A [Homo sapiens] 224 3e-58
gi|4758648 kinesin family member 5B [Homo sapiens] 221 2e-57
gi|4758650 kinesin family member 5C [Homo sapiens] 217 3e-56
gi|116686122 kinesin family member 4 [Homo sapiens] 216 9e-56
gi|13699824 kinesin family member 11 [Homo sapiens] 214 2e-55
gi|150010604 kinesin family member 4B [Homo sapiens] 213 4e-55
gi|46852172 kinesin family member 13B [Homo sapiens] 211 2e-54
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 210 4e-54
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 210 4e-54
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 210 4e-54
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 210 4e-54
gi|148612831 kinesin family member 18A [Homo sapiens] 204 3e-52
gi|38569484 kinesin family member 21A [Homo sapiens] 200 5e-51
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 198 1e-50
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 198 1e-50
gi|30794488 kinesin family member 27 [Homo sapiens] 198 2e-50
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 197 3e-50
gi|122937289 kinesin family member 18B [Homo sapiens] 197 3e-50
gi|7661878 kinesin family member 14 [Homo sapiens] 191 3e-48
>gi|157502184 kinesin family member 6 [Homo sapiens]
Length = 814
Score = 1602 bits (4149), Expect = 0.0
Identities = 814/814 (100%), Positives = 814/814 (100%)
Query: 1 MVKQTIQIFARVKPPVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKF 60
MVKQTIQIFARVKPPVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKF
Sbjct: 1 MVKQTIQIFARVKPPVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKF 60
Query: 61 QRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGII 120
QRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGII
Sbjct: 61 QRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGII 120
Query: 121 PRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQ 180
PRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQ
Sbjct: 121 PRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQ 180
Query: 181 NIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSAT 240
NIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSAT
Sbjct: 181 NIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSAT 240
Query: 241 VRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRNS 300
VRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRNS
Sbjct: 241 VRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRNS 300
Query: 301 MMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRLV 360
MMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRLV
Sbjct: 301 MMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRLV 360
Query: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK 420
IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK
Sbjct: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK 420
Query: 421 VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILVN 480
VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILVN
Sbjct: 421 VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILVN 480
Query: 481 MLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKR 540
MLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKR
Sbjct: 481 MLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKR 540
Query: 541 SSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEAR 600
SSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEAR
Sbjct: 541 SSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEAR 600
Query: 601 SKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKAL 660
SKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKAL
Sbjct: 601 SKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKAL 660
Query: 661 KVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHEWS 720
KVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHEWS
Sbjct: 661 KVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHEWS 720
Query: 721 QLLSNKSSGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQSSTSTPLEDSIPKRPV 780
QLLSNKSSGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQSSTSTPLEDSIPKRPV
Sbjct: 721 QLLSNKSSGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQSSTSTPLEDSIPKRPV 780
Query: 781 SSIPLTGDSQTDSDIIAFIKARQSILQKQCLGSN 814
SSIPLTGDSQTDSDIIAFIKARQSILQKQCLGSN
Sbjct: 781 SSIPLTGDSQTDSDIIAFIKARQSILQKQCLGSN 814
>gi|11641245 kinesin family member 9 isoform 1 [Homo sapiens]
Length = 725
Score = 340 bits (873), Expect = 2e-93
Identities = 225/695 (32%), Positives = 368/695 (52%), Gaps = 64/695 (9%)
Query: 3 KQTIQIFARVKPPVR-KHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQ 61
++ + F RVKP H+ Y D+ S++I L +D+ G VNN++ + FK
Sbjct: 4 RKKVHAFVRVKPTDDFAHEMIRYGDDKR-----SIDIHLKKDIRRGVVNNQQTDWSFKLD 58
Query: 62 RIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIP 121
+ DA+Q+ V+E +AK V L GYNGTI YGQTG+GKT+T+ G E Y RGI+P
Sbjct: 59 GVL-HDASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILP 117
Query: 122 RTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQN 181
R L +F +++ + T +SYLEIYNE +DLL + +TI+E+P Q
Sbjct: 118 RALQQVFRMIEERPTHAITVRVSYLEIYNESLFDLLSTLPYVGP--SVTPMTIVENP-QG 174
Query: 182 IHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSATV 241
+ +K L++H + EE+A +LLF G+TNR+IA MN+ S+RSHCIFTI+L + +
Sbjct: 175 VFIKGLSVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEE 234
Query: 242 RH--AKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRN 299
++ +K++LVDLAGSER+ K+G G +L EA YIN SL +LEQ IIAL ++ R HIP+R
Sbjct: 235 KYITSKINLVDLAGSERLGKSGSEGQVLKEATYINKSLSFLEQAIIALGDQKRDHIPFRQ 294
Query: 300 SMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRL 359
+T L+DSLGGNC ++ + E L+E++S+ RFA R+ L+ E +NE+ +
Sbjct: 295 CKLTHALKDSLGGNCNMVLVTNIYGEAAQLEETLSSLRFASRMKLVTTEPAINEKYDAER 354
Query: 360 VIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMR 419
++K L+KE+ LK ELA+ ++LT + + + D E+ + +R
Sbjct: 355 MVKNLEKELALLKQELAI------HDSLTNRTFVTYDPM--------DEIQIAEINSQVR 400
Query: 420 KVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILV 479
+ +L+ L++ I+ + +E + + R +L Q++ E+ +
Sbjct: 401 R------YLEGTLDEIDIISLRQI--------------KEVFNQFRVVLSQQEQEVESTL 440
Query: 480 N----MLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFS 535
++ + A A+ AG+ +G PE GQ L AP +
Sbjct: 441 RRKYTLIDRNDFAAISAIQKAGL-------VDVDGHLVGEPE-GQNFGLGVAPFSTKPGK 492
Query: 536 ILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVT--IDDNKQILKQRFSEAKALG 593
K S K +R + AFE FK + + +NK IL +R A
Sbjct: 493 ---KAKSKKTFKEPLRPDTPPSKPVAFEEFKNEQGSEINRIFKENKSILNERRKRASETT 549
Query: 594 ESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTM 653
+ IN + +I KE + + + G EN + ++ D++E L +L++ K++Y++
Sbjct: 550 QHINAIKREIDVTKEALNFQKSLREKQGKYENKGLMII-DEEEFLLILKLKDLKKQYRSE 608
Query: 654 FTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAE 688
+ L+ L+ EI++ Q L+D+ + +L EF++W+ E
Sbjct: 609 YQDLRDLRAEIQYCQHLVDQCRHRLLMEFDIWYNE 643
>gi|199560800 kinesin family member 9 isoform 2 [Homo sapiens]
Length = 790
Score = 306 bits (784), Expect = 5e-83
Identities = 222/749 (29%), Positives = 367/749 (48%), Gaps = 107/749 (14%)
Query: 3 KQTIQIFARVKPPVR-KHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQ 61
++ + F RVKP H+ Y D+ S++I L +D+ G VNN++ + FK
Sbjct: 4 RKKVHAFVRVKPTDDFAHEMIRYGDDKR-----SIDIHLKKDIRRGVVNNQQTDWSFKLD 58
Query: 62 RIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIP 121
+ DA+Q+ V+E +AK V L GYNGTI YGQTG+GKT+T+ G E Y RGI+P
Sbjct: 59 GVL-HDASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILP 117
Query: 122 RTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQN 181
R L +F +++ + T +SYLEIYNE +DLL + +TI+E+P Q
Sbjct: 118 RALQQVFRMIEERPTHAITVRVSYLEIYNESLFDLLSTLPYVGP--SVTPMTIVENP-QG 174
Query: 182 IHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSATV 241
+ +K L++H + EE+A +LLF G+TNR+IA MN+ S+RSHCIFTI+L + +
Sbjct: 175 VFIKGLSVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEE 234
Query: 242 RH--AKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRN 299
++ +K++LVDLAGSER+ K+G G +L EA YIN SL +LEQ IIAL ++ R HIP+R
Sbjct: 235 KYITSKINLVDLAGSERLGKSGSEGQVLKEATYINKSLSFLEQAIIALGDQKRDHIPFRQ 294
Query: 300 SMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRL 359
+T L+DSLGGNC ++ + E L+E++S+ RFA R+ L+ E
Sbjct: 295 CKLTHALKDSLGGNCNMVLVTNIYGEAAQLEETLSSLRFASRMKLVTTEPA--------- 345
Query: 360 VIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMR 419
I E D MV ++ AL + EL + L D +++
Sbjct: 346 --------INEKYDAERMVKNLEKELALLKQELAIHDSLTNRTFVTYDPMDEIQIAEINS 397
Query: 420 KVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILV 479
+V +L+ L++ I+ + +E + + R +L Q++ E+ +
Sbjct: 398 QVRR---YLEGTLDEIDIISLRQI--------------KEVFNQFRVVLSQQEQEVESTL 440
Query: 480 N----MLKKEKKKAQEALHLAGM---DRREFRQSQSPPFRLG----NPEEGQRMRL---- 524
++ + A A+ AG+ D + + F LG + + G++ +
Sbjct: 441 RRKYTLIDRNDFAAISAIQKAGLVDVDGHLVGEPEGQNFGLGVAPFSTKPGKKAKSKKTF 500
Query: 525 ------------SSAPSQAQDFSILGKRSSLL--HKKIGMREEMSLGCQE---------- 560
+S+P +D + + L K G ++M +E
Sbjct: 501 KEPLSSLARKEGASSPVNGKDLDYVSTSKTQLVPSSKDGDVKDMLSRDRETSSIEPLPSD 560
Query: 561 -------------------AFEIFKRDHADSVT--IDDNKQILKQRFSEAKALGESINEA 599
AFE FK + + +NK IL +R A + IN
Sbjct: 561 SPKEELRPIRPDTPPSKPVAFEEFKNEQGSEINRIFKENKSILNERRKRASETTQHINAI 620
Query: 600 RSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKA 659
+ +I KE + + + G EN + ++ D++E L +L++ K++Y++ + L+
Sbjct: 621 KREIDVTKEALNFQKSLREKQGKYENKGLMII-DEEEFLLILKLKDLKKQYRSEYQDLRD 679
Query: 660 LKVEIEHLQLLMDKAKVKLQKEFEVWWAE 688
L+ EI++ Q L+D+ + +L EF++W+ E
Sbjct: 680 LRAEIQYCQHLVDQCRHRLLMEFDIWYNE 708
>gi|199560791 kinesin family member 9 isoform 2 [Homo sapiens]
Length = 790
Score = 306 bits (784), Expect = 5e-83
Identities = 222/749 (29%), Positives = 367/749 (48%), Gaps = 107/749 (14%)
Query: 3 KQTIQIFARVKPPVR-KHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQ 61
++ + F RVKP H+ Y D+ S++I L +D+ G VNN++ + FK
Sbjct: 4 RKKVHAFVRVKPTDDFAHEMIRYGDDKR-----SIDIHLKKDIRRGVVNNQQTDWSFKLD 58
Query: 62 RIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIP 121
+ DA+Q+ V+E +AK V L GYNGTI YGQTG+GKT+T+ G E Y RGI+P
Sbjct: 59 GVL-HDASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILP 117
Query: 122 RTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQN 181
R L +F +++ + T +SYLEIYNE +DLL + +TI+E+P Q
Sbjct: 118 RALQQVFRMIEERPTHAITVRVSYLEIYNESLFDLLSTLPYVGP--SVTPMTIVENP-QG 174
Query: 182 IHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSATV 241
+ +K L++H + EE+A +LLF G+TNR+IA MN+ S+RSHCIFTI+L + +
Sbjct: 175 VFIKGLSVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEE 234
Query: 242 RH--AKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRN 299
++ +K++LVDLAGSER+ K+G G +L EA YIN SL +LEQ IIAL ++ R HIP+R
Sbjct: 235 KYITSKINLVDLAGSERLGKSGSEGQVLKEATYINKSLSFLEQAIIALGDQKRDHIPFRQ 294
Query: 300 SMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRL 359
+T L+DSLGGNC ++ + E L+E++S+ RFA R+ L+ E
Sbjct: 295 CKLTHALKDSLGGNCNMVLVTNIYGEAAQLEETLSSLRFASRMKLVTTEPA--------- 345
Query: 360 VIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMR 419
I E D MV ++ AL + EL + L D +++
Sbjct: 346 --------INEKYDAERMVKNLEKELALLKQELAIHDSLTNRTFVTYDPMDEIQIAEINS 397
Query: 420 KVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILV 479
+V +L+ L++ I+ + +E + + R +L Q++ E+ +
Sbjct: 398 QVRR---YLEGTLDEIDIISLRQI--------------KEVFNQFRVVLSQQEQEVESTL 440
Query: 480 N----MLKKEKKKAQEALHLAGM---DRREFRQSQSPPFRLG----NPEEGQRMRL---- 524
++ + A A+ AG+ D + + F LG + + G++ +
Sbjct: 441 RRKYTLIDRNDFAAISAIQKAGLVDVDGHLVGEPEGQNFGLGVAPFSTKPGKKAKSKKTF 500
Query: 525 ------------SSAPSQAQDFSILGKRSSLL--HKKIGMREEMSLGCQE---------- 560
+S+P +D + + L K G ++M +E
Sbjct: 501 KEPLSSLARKEGASSPVNGKDLDYVSTSKTQLVPSSKDGDVKDMLSRDRETSSIEPLPSD 560
Query: 561 -------------------AFEIFKRDHADSVT--IDDNKQILKQRFSEAKALGESINEA 599
AFE FK + + +NK IL +R A + IN
Sbjct: 561 SPKEELRPIRPDTPPSKPVAFEEFKNEQGSEINRIFKENKSILNERRKRASETTQHINAI 620
Query: 600 RSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKA 659
+ +I KE + + + G EN + ++ D++E L +L++ K++Y++ + L+
Sbjct: 621 KREIDVTKEALNFQKSLREKQGKYENKGLMII-DEEEFLLILKLKDLKKQYRSEYQDLRD 679
Query: 660 LKVEIEHLQLLMDKAKVKLQKEFEVWWAE 688
L+ EI++ Q L+D+ + +L EF++W+ E
Sbjct: 680 LRAEIQYCQHLVDQCRHRLLMEFDIWYNE 708
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 260 bits (665), Expect = 3e-69
Identities = 194/581 (33%), Positives = 291/581 (50%), Gaps = 75/581 (12%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
F F +F ++ Q V+ A+P+ SVL GYNGTIFAYGQTG+GKTFT+ G R
Sbjct: 61 FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
Query: 118 GIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
GIIP + ++IF + K + + +SYLEIYNE DLL + ++ + E
Sbjct: 121 GIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGK-------DQTQRLEVKE 173
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
PD +++K+L+ + ++ ++ LG NR + T MN+ S+RSH IFTI + E
Sbjct: 174 RPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEK 233
Query: 237 G---SATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRS 293
G + VR KLHLVDLAGSER AKTG G L EA INLSL L VI AL + +
Sbjct: 234 GIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST 293
Query: 294 HIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNE 353
H+PYRNS +T +L+DSLGGN T M A + N DE+IST R+A R IKN+A +NE
Sbjct: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353
Query: 354 EINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLE 413
+ L +++ QKEI+ELK +L + E ++ +++ E +D D E
Sbjct: 354 DPKDAL-LRQFQKEIEELKKKL------EEGEEISGSDISGSE---------EDDDEEGE 397
Query: 414 VGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLR-------- 465
VG D K KK+ DK I + E K + + ++EEE K R
Sbjct: 398 VGEDGEK-RKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREK 456
Query: 466 DILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLS 525
D+LK + ++L + EKK + + G+D + Q N E +R
Sbjct: 457 DLLKAQQEHQSLLEKLSALEKK-----VIVGGVDLLAKAEEQEKLLEESNMELEERR--- 508
Query: 526 SAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQR 585
KR+ L +++ +E+ L +E + + + + +
Sbjct: 509 -------------KRAEQLRRELEEKEQERLDIEEKYTSLQEE-------------AQGK 542
Query: 586 FSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENM 626
+ K + + A+S++ L++E QR I+ G+ EN+
Sbjct: 543 TKKLKKVWTMLMAAKSEMADLQQE-HQREIE----GLLENI 578
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 243 bits (621), Expect = 4e-64
Identities = 207/727 (28%), Positives = 361/727 (49%), Gaps = 78/727 (10%)
Query: 4 QTIQIFARVKPPVRKHQQGIYS--IDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQ 61
+++++ R +P K + Y +D D KL + + P+ A F F
Sbjct: 8 ESVRVVVRCRPMNGKEKAASYDKVVDVDVKL-GQVSVKNPKGTAHEMPKT------FTFD 60
Query: 62 RIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIP 121
++D +A Q +++ +P+ SVL G+NGTIFAYGQTG+GKT+T+ G RG+IP
Sbjct: 61 AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP 120
Query: 122 RTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQN 181
+ +IF + + ++ Y SYLEIY E DLL S + ++ + E PD
Sbjct: 121 NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL-------SKDQTKRLELKERPDTG 173
Query: 182 IHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKE---PGS 238
+++K+L+ + +E +++ +G+ NR + T MN+ S+RSH IF I + E G
Sbjct: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233
Query: 239 ATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYR 298
+R KL+LVDLAGSER AKTG G L EA INLSL L VI AL + +HIPYR
Sbjct: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYR 293
Query: 299 NSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPR 358
+S +T +L+DSLGGN T M+A + N++E+++T R+A R IKN+ +NE+
Sbjct: 294 DSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDA 353
Query: 359 LVIKRLQKEIQELKDEL--AMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGA 416
L ++ Q+EI LK +L + +R E E E+++ + E G
Sbjct: 354 L-LREFQEEIARLKAQLEKRSIGRRKRREKRREGG----GSGGGGEEEEEEGEEGEEEGD 408
Query: 417 DMRKVHHCFHHLKKLLNDKK-ILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEI 475
D K + +KL +K+ I+E++++ +E K LKE+E +K+ D+ +++D
Sbjct: 409 D--KDDYWREQQEKLEIEKRAIVEDHSLVAEEK----MRLLKEKE-KKMEDLRREKD--- 458
Query: 476 NILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFS 535
ML + K + L + G + + Q E ++ R
Sbjct: 459 --AAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKR------------ 504
Query: 536 ILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGES 595
R + +++ R+E +L +E + +++ +D + LK+ FS+ +A+
Sbjct: 505 ----REREIQQQMESRDEETLELKETYSSLQQE------VDIKTKKLKKLFSKLQAVKAE 554
Query: 596 INEARSKIGHLKE----EITQRHIQQVALGISENMAVPLMPDQQEEKL--RSQLEEEKRR 649
I++ + + H+KE E TQ + + L + + +P +++ K+ R+ +EE+
Sbjct: 555 IHDLQEE--HIKERQELEQTQNELTR-ELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDH 611
Query: 650 YKT-MFTRLKALKV------EIEHLQLLMDKAKVKLQKEFEV-WWAEEATNLQVNSPAVN 701
+K TRL+ ++ + + + L A++ + E + AE L+++ P+
Sbjct: 612 WKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRT 671
Query: 702 SLDHTKP 708
+ D+ P
Sbjct: 672 TRDYEGP 678
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 234 bits (597), Expect = 2e-61
Identities = 173/523 (33%), Positives = 265/523 (50%), Gaps = 50/523 (9%)
Query: 57 KFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSD 116
+F F + D E ++ IA P+ V GYNGTIFAYGQTGSGK+FT+ G + S
Sbjct: 51 QFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQ 110
Query: 117 RGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
RGIIPR ++FE +Q + + SYLEIYNE DLL + K+ + E
Sbjct: 111 RGIIPRAFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLL-------GADTKQKLELKE 163
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK-- 234
P++ +++K L++H + + +++ G NR + T MN+ S+RSH IFTI +
Sbjct: 164 HPEKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAV 223
Query: 235 -EPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRS 293
E G +R KL+LVDLAGSER +KTG G L EA INLSL L VI AL +
Sbjct: 224 DERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK 283
Query: 294 HIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNE 353
H+PYR+S +T +L+DSLGGN T M+A LS N DE++ST R+A R I+N+ +NE
Sbjct: 284 HVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINE 343
Query: 354 EINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAEL----LQL-EKLITSFLEDQDS 408
+ L ++ Q+EI++LK L AL ++ +Q+ EKL+ + D
Sbjct: 344 DPKDAL-LREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDV 402
Query: 409 DSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDIL 468
++ ++ +R+ + L +L D K ++E +L + +
Sbjct: 403 EAEKQL---IREEYE--ERLARLKADYK-------------------AEQESRARLEEDI 438
Query: 469 KQRDNEINILVNMLKKEKKKAQEALHLAG-------MDRREFRQSQS--PPFRLGNPEEG 519
N ++ ++ L++ +K EA+ G M R EF S P F+ +
Sbjct: 439 TAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKAEVMSRAEFASSAEYPPAFQYETVVKP 498
Query: 520 QRMRLS-SAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEA 561
+ + + PS + + R + L K + E+SLG E+
Sbjct: 499 KVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSES 541
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 234 bits (597), Expect = 2e-61
Identities = 173/523 (33%), Positives = 265/523 (50%), Gaps = 50/523 (9%)
Query: 57 KFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSD 116
+F F + D E ++ IA P+ V GYNGTIFAYGQTGSGK+FT+ G + S
Sbjct: 51 QFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQ 110
Query: 117 RGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
RGIIPR ++FE +Q + + SYLEIYNE DLL + K+ + E
Sbjct: 111 RGIIPRAFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLL-------GADTKQKLELKE 163
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK-- 234
P++ +++K L++H + + +++ G NR + T MN+ S+RSH IFTI +
Sbjct: 164 HPEKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAV 223
Query: 235 -EPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRS 293
E G +R KL+LVDLAGSER +KTG G L EA INLSL L VI AL +
Sbjct: 224 DERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK 283
Query: 294 HIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNE 353
H+PYR+S +T +L+DSLGGN T M+A LS N DE++ST R+A R I+N+ +NE
Sbjct: 284 HVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINE 343
Query: 354 EINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAEL----LQL-EKLITSFLEDQDS 408
+ L ++ Q+EI++LK L AL ++ +Q+ EKL+ + D
Sbjct: 344 DPKDAL-LREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDV 402
Query: 409 DSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDIL 468
++ ++ +R+ + L +L D K ++E +L + +
Sbjct: 403 EAEKQL---IREEYE--ERLARLKADYK-------------------AEQESRARLEEDI 438
Query: 469 KQRDNEINILVNMLKKEKKKAQEALHLAG-------MDRREFRQSQS--PPFRLGNPEEG 519
N ++ ++ L++ +K EA+ G M R EF S P F+ +
Sbjct: 439 TAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKAEVMSRAEFASSAEYPPAFQYETVVKP 498
Query: 520 QRMRLS-SAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEA 561
+ + + PS + + R + L K + E+SLG E+
Sbjct: 499 KVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSES 541
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 232 bits (592), Expect = 9e-61
Identities = 183/558 (32%), Positives = 278/558 (49%), Gaps = 76/558 (13%)
Query: 6 IQIFARVKPPVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQRIFD 65
I++F R++PP + S D ++ L L ++ L +++ E F F + D
Sbjct: 27 IKVFVRIRPPAERSG----SADGEQNLC--LSVLSSTSLR---LHSNPEPKTFTFDHVAD 77
Query: 66 QDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAE----RYSDRGIIP 121
D QE+VF +AK + S ++GYNGTIFAYGQTGSGKTFT+ G +E ++ RG+IP
Sbjct: 78 VDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIP 137
Query: 122 RTLSYIFEQLQKD-----SSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
R+ Y+F + ++ + K + S++EIYNE YDLLD L + K
Sbjct: 138 RSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLREHIK----- 192
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
+ + + T+ EA +L G NR +A T MN+ S+RSH +FTI + S E
Sbjct: 193 ---KGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEK 249
Query: 237 GS--ATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIAL---SEKH 291
+ +R + L+LVDLAGSER T G L EA IN SL L QVI AL
Sbjct: 250 SNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGK 309
Query: 292 RSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVL 351
+ H+ YR+S +T +LRDSLGGN T +IA + R E++ST FAQR LIKN+AV+
Sbjct: 310 QRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVV 369
Query: 352 NEEINPRLVIKRLQKEIQELKDELA-MVTGEQRTEALTEAELLQLEKLITSFLE------ 404
NE+ + +LQ E++ LK++LA + +G+ E+ L +K T+++E
Sbjct: 370 NEDTQGN--VSQLQAEVKRLKEQLAELASGQTPPES-----FLTRDKKKTNYMEYFQEAM 422
Query: 405 ------DQDSDSRLEVGA---DMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEP 455
+Q+ S +E D+ F K++ K E+ + E ++ +
Sbjct: 423 LFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMI--VKFREDQIIRLEKLHKESRGG 480
Query: 456 LKEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGN 515
EE +L L + NEI L ++ + A+ A M+ R
Sbjct: 481 FLPEEQDRL---LSELRNEIQTLREQIEHHPRVAKYA-----MENHSLR----------- 521
Query: 516 PEEGQRMRLSSAPSQAQD 533
EE +R+RL +AQ+
Sbjct: 522 -EENRRLRLLEPVKRAQE 538
Score = 34.7 bits (78), Expect = 0.37
Identities = 103/566 (18%), Positives = 232/566 (40%), Gaps = 87/566 (15%)
Query: 165 SLEDLPKVTILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSH 224
S ++L ++ E + +L+N T + + NL+ L + + R++
Sbjct: 866 SYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEK-----------ERNN 914
Query: 225 CIFTIHLSSKEPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVI 284
+ KE S + L +++ E+ +T + + + + SL E+VI
Sbjct: 915 KLSLQFEEDKENSSKEI----LKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVI 970
Query: 285 IALSEKHRSHIPYRNSMMTSV--LRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRV 342
+L + S +M + LR S+ T I TL E ++++ C++
Sbjct: 971 SSLEKSRDSDKKVVADLMNQIQELRTSVCEK--TETIDTLKQELKDIN-----CKY---- 1019
Query: 343 ALIKNEAVLNEEINPRLVIKRLQKEIQELKDELAM-VTGEQRTEALTEAELLQLEKLITS 401
N A+++ E R++IK+ + +I +LK+ L + + E + +L + +
Sbjct: 1020 ----NSALVDRE-ESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNM 1074
Query: 402 FLEDQDSDSRLEVGAD---------MRKVHHCFHHLKKLLNDKKILENNTVSS-----ES 447
E S L A ++++ H + K+ + KK N + +S
Sbjct: 1075 LTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDS 1134
Query: 448 KDQDCQEPLKEEEYRK-LRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQS 506
+D Q P ++ L +L+ ++ EI + K + E L + RE + +
Sbjct: 1135 AAEDPQSPKTPPHFQTHLAKLLETQEQEIED-----GRASKTSLEHLVTKLNEDREVKNA 1189
Query: 507 QSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFK 566
+ + E + +RL S +++ + G+ + +K E
Sbjct: 1190 EILRMK-EQLREMENLRLESQQLIEKNWLLQGQLDDIKRQK---------------ENSD 1233
Query: 567 RDHADSVTI-DDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALG--IS 623
++H D+ + ++ ++ +K+R +++K + E + + ++ + ++ + + ++ + + +
Sbjct: 1234 QNHPDNQQLKNEQEESIKERLAKSKIVEEML-KMKADLEEVQSALYNKEMECLRMTDEVE 1292
Query: 624 ENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHL----------QLLMDK 673
+ Q++E+LRS+LEE + ++ L+ ++E L Q L K
Sbjct: 1293 RTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQK 1352
Query: 674 AK--VKLQKEFEVWWAEEATNLQVNS 697
+ V+L+KE V AEE L+ +
Sbjct: 1353 IQYVVRLKKE-NVRLAEETEKLRAEN 1377
Score = 33.9 bits (76), Expect = 0.62
Identities = 64/349 (18%), Positives = 139/349 (39%), Gaps = 42/349 (12%)
Query: 345 IKNEA-VLNEEINPRLVIKRLQKEIQELKDE---LAMVTGEQRTEALTEAELLQLEKLIT 400
++NE L E+I + + E L++E L ++ +R + + + +LEK +
Sbjct: 493 LRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEKAFS 552
Query: 401 SFLEDQDSDSRLEVGADMRKVHHC-FHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEE 459
+ SD + + + C F + +KL ++L+ T + SK +
Sbjct: 553 EISGMEKSDKNQQGFSPKAQKEPCLFANTEKL--KAQLLQIQTELNNSK----------Q 600
Query: 460 EYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFR------L 513
EY + +++ ++R E+ + L+K + L +R+ SQ +
Sbjct: 601 EYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQ-EVSQLNKIHAETLKII 659
Query: 514 GNPEEGQRMRLSSAPSQAQDFSILG----KRSSLLHKKIGMREEMSLGCQEAFEIFKRDH 569
P + ++ P + + G + SS+L I ++AFE +
Sbjct: 660 TTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEEL 719
Query: 570 ADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAVP 629
T+ + L+ + E + + + K+ H ++ + L SE +
Sbjct: 720 R---TVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQE-------LFSSERIDWT 769
Query: 630 LMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKL 678
+Q+E+L SQL +++ + T+ LK E+ L++++ A +L
Sbjct: 770 ----KQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKEL 814
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 231 bits (590), Expect = 2e-60
Identities = 207/693 (29%), Positives = 328/693 (47%), Gaps = 113/693 (16%)
Query: 55 SYKFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERY 114
S F F R+F + + V+E IA P+ S + GYNGTIFAYGQT SGKT+T+ G +
Sbjct: 44 SKSFNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHL 103
Query: 115 SDRGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTI 174
G+IPR + IF++++K + + +SY+EIYNE DLL + + + I
Sbjct: 104 ---GVIPRAIHDIFQKIKKFPDREFLLRVSYMEIYNETITDLL------CGTQKMKPLII 154
Query: 175 LEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK 234
ED ++N+++ +LT T E AL + G+ +R ET MNQ S+RSH IF + L S+
Sbjct: 155 REDVNRNVYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESR 214
Query: 235 EPG-----SATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE 289
E G +V+ + L+LVDLAGSER A+TG G L E IN SL L QVI LS+
Sbjct: 215 EKGEPSNCEGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSD 274
Query: 290 -KHRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNE 348
+ I YR+S +T +L++SLGGN T +I T++ + DE+++ +FA +KN
Sbjct: 275 GQVGGFINYRDSKLTRILQNSLGGNAKTRIICTIT--PVSFDETLTALQFASTAKYMKNT 332
Query: 349 AVLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDS 408
+NE ++KR +KEI +LK +L V+ E R +A+ + +L QL LE++D
Sbjct: 333 PYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQL-------LEEKDL 385
Query: 409 DSRLEVGADMRKVHHCFHHLKKLLNDKKILENNT-VSSESKDQDCQEPLKEEEYRK---- 463
L+K+ N+K +EN T + S Q+ LK + R+
Sbjct: 386 -------------------LQKVQNEK--IENLTRMLVTSSSLTLQQELKAKRKRRVTWC 424
Query: 464 LRDILKQRD----NEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQ------------ 507
L I K ++ ++ NI N+ K K + L +D +S
Sbjct: 425 LGKINKMKNSNYADQFNIPTNITTKTHKLSINLLR--EIDESVCSESDVFSNTLDTLSEI 482
Query: 508 --SPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIF 565
+P +L N E + S S D+ L L + +EEM L +E ++
Sbjct: 483 EWNPATKLLNQENIE----SELNSLRADYDNLVLDYEQLRTE---KEEMELKLKEKNDLD 535
Query: 566 KRDHADSVTIDDNKQILKQRFSEAKAL------------------GESINEARSKIGHLK 607
+ + + T D + L S K L E + E +I L+
Sbjct: 536 EFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQ 595
Query: 608 EEITQRHIQQVALGISENM-----------------AVPLMPDQQEEKLRSQLEEEKRRY 650
E I + ++ + + +S ++ V L ++ LRS+ E K +
Sbjct: 596 EYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKM 655
Query: 651 KTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFE 683
K + T K ++ +I+ Q ++ AK K+Q + E
Sbjct: 656 KELATTYKQMENDIQLYQSQLE-AKKKMQVDLE 687
Score = 48.1 bits (113), Expect = 3e-05
Identities = 80/370 (21%), Positives = 159/370 (42%), Gaps = 48/370 (12%)
Query: 367 EIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRKVHHCFH 426
EI+ LK++ T + E + E E ++L +++ LE+ S ++ D+R V
Sbjct: 1645 EIEHLKEQFE--TQKLNLENI-ETENIRLTQILHENLEEMRSVTKER--DDLRSVE---- 1695
Query: 427 HLKKLLNDKKILENNTVSSESKDQDCQEPLK---------EEEYRKLRDILKQRDNEINI 477
+ L ++ L+ N + ++D + QE LK +E KLR I+ ++ NEI+
Sbjct: 1696 --ETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Query: 478 LV-------NMLKKEKKKAQEALHLAGMDRREFRQS--------QSPPFRLGNPEEGQRM 522
+ + LK + K QE L +A M +E +++ +L N ++ +
Sbjct: 1754 MQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKD--L 1811
Query: 523 RLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQIL 582
S+A Q + + L+ K + E E ++ K+ S+T+ ++
Sbjct: 1812 ENSNAKLQEKIQELKANEHQLITLKKDVNETQKK-VSEMEQLKKQIKDQSLTLS---KLE 1867
Query: 583 KQRFSEAKALGESINEARSKIGHLK-----EEITQRHIQQVALGISENMAVPLMPDQQEE 637
+ + A+ L E++ E +S + EE + Q+ + E A L Q+ +
Sbjct: 1868 IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927
Query: 638 KLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNS 697
R +E K + ++ ++I +Q +DK+K +LQK+ + +E L+V
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKE 1987
Query: 698 PAVNSLDHTK 707
++ H K
Sbjct: 1988 DV--NMSHKK 1995
Score = 46.6 bits (109), Expect = 9e-05
Identities = 77/399 (19%), Positives = 159/399 (39%), Gaps = 39/399 (9%)
Query: 306 LRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPR-LVIKRL 364
L + G ++ L LE + D + + ++ E +L E+ ++RL
Sbjct: 700 LTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERL 759
Query: 365 QKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLED--QDSDSRLEVGADMRKVH 422
+KEIQ+ +EL ++T E+ +E++ E + LE+ + D ++ +
Sbjct: 760 RKEIQDKSEELHIITSEKDK---LFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTD 816
Query: 423 HCFHHLKKLLND-----KKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINI 477
F + K L D K +LE N E +Q+ KE + K L E++
Sbjct: 817 QEFQNFKTLHMDFEQKYKMVLEEN----ERMNQEIVNLSKEAQ--KFDSSLGALKTELSY 870
Query: 478 LVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSIL 537
L+++ ++ QE L+ + + S L E + + ++ L
Sbjct: 871 KTQELQEKTREVQERLNEMEQLKEQLENRDS---TLQTVEREKTLITEKLQQTLEEVKTL 927
Query: 538 GKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTID-DNKQILKQRFSEAKALGESI 596
+ L +++ Q + K D D+V ++ D ++ L+ K E+I
Sbjct: 928 TQEKDDL-------KQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI 980
Query: 597 NEARSKIG-------HLKEEI--TQRHIQQVALGISENMAVPLMPDQ--QEEKLRSQLEE 645
N +SKI H++E T+ QQ +GI + + Q + +++ E
Sbjct: 981 NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIE 1040
Query: 646 EKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFEV 684
++R+ ++ L+ +E + ++ K L++ E+
Sbjct: 1041 QQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEM 1079
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/304 (20%), Positives = 135/304 (44%), Gaps = 32/304 (10%)
Query: 346 KNEAVLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLED 405
K+ A+L EI + KRLQ+ E+K QR + + ++E QL++ I +
Sbjct: 1412 KDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVA- 1470
Query: 406 QDSDSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLR 465
LE +++ H C ++ +N+ ++ + + S Q E + ++ K++
Sbjct: 1471 ----KHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQ 1526
Query: 466 DILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLS 525
+I +++ + NI K+ + QE ++ + ++F++ + E + + L+
Sbjct: 1527 EIY-EKEEQFNI------KQISEVQEKVN----ELKQFKEHRKAKDSALQSIESKMLELT 1575
Query: 526 SAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEI----FKRDHADSVTIDDNKQI 581
+ ++Q+ + I +EEM QEA +I K + + V Q
Sbjct: 1576 NRLQESQE---------EIQIMIKEKEEMK-RVQEALQIERDQLKENTKEIVAKMKESQE 1625
Query: 582 LKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRS 641
+ +F + A+ E+ E +I HLKE+ + + + +EN+ + + + E++RS
Sbjct: 1626 KEYQFLKMTAVNET-QEKMCEIEHLKEQFETQKLNLENIE-TENIRLTQILHENLEEMRS 1683
Query: 642 QLEE 645
+E
Sbjct: 1684 VTKE 1687
Score = 42.7 bits (99), Expect = 0.001
Identities = 80/430 (18%), Positives = 161/430 (37%), Gaps = 41/430 (9%)
Query: 319 IATLSLEKRNLD---ESISTCRFAQRVALIKNEAVLNEEINPRLVIKRLQKEIQELKDEL 375
I L E +N + E + T R L +N + R V+K LQK + +D L
Sbjct: 1160 IENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHL 1219
Query: 376 AMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRKVHHCFHHLKKLLNDK 435
E L E L++ + +++ L++ +++K
Sbjct: 1220 RGYIREIEATGLQTKEELKIAHI------------------HLKEHQETIDELRRSVSEK 1261
Query: 436 KILENNTVSSESKDQDCQE--PLKEEEYRKLRDI--LKQRDNEINILVNMLKKEKKKAQE 491
NT E QE P+ EE L ++ + + +N L + ++ K
Sbjct: 1262 TAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDST 1321
Query: 492 ALHLAGMDR----REFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKK 547
L M+R +F++SQ L + + + + + + ++
Sbjct: 1322 TLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1381
Query: 548 IGMREEMSLGCQE----------AFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESIN 597
++E SL +E E FK + + I+ L +R E+ +S+
Sbjct: 1382 SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1441
Query: 598 EARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRL 657
+ + + L +E+ Q Q+ I E +A L +++ + L+E++ + L
Sbjct: 1442 KEKDDLQRL-QEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL 1500
Query: 658 KALKVEIEHLQLLMDKAKVKLQKEF-EVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQ 716
+ EI +Q ++ KLQ + E++ EE N++ S ++ K F + ++
Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK 1560
Query: 717 HEWSQLLSNK 726
Q + +K
Sbjct: 1561 DSALQSIESK 1570
Score = 38.5 bits (88), Expect = 0.025
Identities = 69/334 (20%), Positives = 154/334 (46%), Gaps = 54/334 (16%)
Query: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK 420
+ QK++ E++ + + T + E E L L + + LE+ S ++ ++R+
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM--KSVMKERDNLRR 1896
Query: 421 VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLK-----EEEYRKLRDILKQRDNEI 475
V KL D+ L+ + ++++D + Q+ LK +E+++ D L+++ +E
Sbjct: 1897 VEETL----KLERDQ--LKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEK 1950
Query: 476 NILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFS 535
I ++ ++K+ K+++ L +++ ++ Q +E Q +R+ +D +
Sbjct: 1951 TIQISDIQKDLDKSKDEL------QKKIQELQK--------KELQLLRVK------EDVN 1990
Query: 536 ILGKRSSLLHKKIGMREEMSLGCQ----EAFEIFKRDHADSVTIDDNKQILKQRFSEAKA 591
+ K+ + + + E +L Q + F++ K+ H ++++ + + K+R E +
Sbjct: 1991 MSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHE---SLEEIRIVAKER-DELRR 2046
Query: 592 LGESINEARSK-IGHLKEEITQ-RHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRR 649
+ ES+ R + I L+E I + R QV L+ D Q+ L L E+ R
Sbjct: 2047 IKESLKMERDQFIATLREMIARDRQNHQV------KPEKRLLSDGQQH-LTESLREKCSR 2099
Query: 650 YKTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFE 683
K + R + +H + L ++ + L+KE E
Sbjct: 2100 IKELLKRYSEMD---DHYECL-NRLSLDLEKEIE 2129
Score = 37.4 bits (85), Expect = 0.056
Identities = 63/320 (19%), Positives = 130/320 (40%), Gaps = 33/320 (10%)
Query: 361 IKRLQKEIQELKDELAMVTGE--QRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADM 418
+K +++QE + +L V E + + + E E L+ E + RLE+
Sbjct: 1129 LKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA--- 1185
Query: 419 RKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINIL 478
+K++ + +K + ++K+L+ S E++ + ++E E L Q E+ I
Sbjct: 1186 QKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL-----QTKEELKIA 1240
Query: 479 VNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILG 538
LK+ ++ E RR + + + E+ P ++ +L
Sbjct: 1241 HIHLKEHQETIDEL-------RRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLP 1293
Query: 539 KRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINE 598
+ + M E L Q +D I+ + L ++F E++ +S+ +
Sbjct: 1294 NVKEVSETQETMNELELLTEQST----TKDSTTLARIEMERLRLNEKFQESQEEIKSLTK 1349
Query: 599 ARSKIGHLKEEITQRHIQQVALGISENMA-VPLMPDQQEEKLR--------SQLEEEKRR 649
R + +KE + +H Q+ I E +A + +QE+ L +++ E +
Sbjct: 1350 ERDNLKTIKEALEVKH-DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQ 1408
Query: 650 YKTMFTRLKALKVEIEHLQL 669
+K + L L++EIE L L
Sbjct: 1409 FKPKDSAL--LRIEIEMLGL 1426
Score = 36.6 bits (83), Expect = 0.096
Identities = 74/384 (19%), Positives = 156/384 (40%), Gaps = 60/384 (15%)
Query: 350 VLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKL----------- 398
VL+EE +K + E QE +EL ++T + T+ T +++E+L
Sbjct: 1284 VLHEEQELLPNVKEVS-ETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQE 1342
Query: 399 -ITSFLEDQDS----DSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQ 453
I S +++D+ LEV D K H + + + + +++ + KD +
Sbjct: 1343 EIKSLTKERDNLKTIKEALEVKHDQLKEH--IRETLAKIQESQSKQEQSLNMKEKDNETT 1400
Query: 454 EPLKEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDR------REFRQSQ 507
+ + E E K +D R I I + L K +++ + + ++ +E QS+
Sbjct: 1401 KIVSEMEQFKPKDSALLR---IEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSE 1457
Query: 508 SPPFRLG-------NPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKI----------GM 550
S + + E + ++++ + Q+ +I R +L K+ +
Sbjct: 1458 SDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAI 1517
Query: 551 REEMSLGCQEAFEIFKRDHADSVT-IDDNKQILKQRFSEAKALGESINEARSKIGHLKEE 609
+++ QE +E ++ + ++ + + LKQ KA ++ SK+ L
Sbjct: 1518 NDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNR 1577
Query: 610 ITQRHIQ-QVALGISENM-----AVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKV- 662
+ + + Q+ + E M A+ + DQ +E + + + K + + LK V
Sbjct: 1578 LQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVN 1637
Query: 663 -------EIEHLQLLMDKAKVKLQ 679
EIEHL+ + K+ L+
Sbjct: 1638 ETQEKMCEIEHLKEQFETQKLNLE 1661
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 226 bits (576), Expect = 7e-59
Identities = 175/647 (27%), Positives = 307/647 (47%), Gaps = 91/647 (14%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
F F ++D + Q +++ +P+ SVL G+NGT+FAYGQTG+GKT+T+ G R
Sbjct: 58 FTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
Query: 118 GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILED 177
G+IP +IF + + ++ Y SYLEIY E DLL S E ++ + E+
Sbjct: 118 GVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL-------SKEPGKRLELKEN 170
Query: 178 PDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPG 237
P+ +++K+L+ +E +++ LG+ R + T MN+ S+RSH IF I + E G
Sbjct: 171 PETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERG 230
Query: 238 SAT---VRHAKLHLVDLAGSERVAKTG------------------------VGGHLLTEA 270
S +R KL+LVDLAGSER K G GG EA
Sbjct: 231 SDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEA 290
Query: 271 KYINLSLHYLEQVIIALSEKHRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLD 330
INLSL L VI AL+ +HIPYR+S +T +L+DSLGGN T M+ATL + D
Sbjct: 291 SKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYD 350
Query: 331 ESISTCRFAQRVALIKNEAVLNEEINPRLVIKRLQKEIQELKDEL---------AMVTGE 381
ES+ST RFA R IKN+ +NE+ L ++ Q+EI LK +L
Sbjct: 351 ESLSTLRFANRAKNIKNKPRVNEDPKDTL-LREFQEEIARLKAQLEKRGMLGKRPRRKSS 409
Query: 382 QRTEALTEAELLQLEKLITSFLEDQDSDSR---------LEVGADMRKVHHCFHHLKKLL 432
+R +A++ +I +++ +++ D+ LE + ++ ++L
Sbjct: 410 RRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLE 469
Query: 433 NDK-KILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQE 491
+K I ++ ++ SE K + L EE+ + L D+ +++ +L + K +
Sbjct: 470 EEKAAIQDDRSLVSEEK-----QKLLEEKEKMLEDLRREQQ-----ATELLAAKYKAMES 519
Query: 492 ALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGMR 551
L + G + + Q L E ++ R ++ M+
Sbjct: 520 KLLIGGRNIMDHTNEQQKMLELKRQEIAEQKR----------------------REREMQ 557
Query: 552 EEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEIT 611
+EM L +E E+ + ++ + LK+ +++ +A+ I + + +++++
Sbjct: 558 QEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLE 617
Query: 612 QRHIQQV-ALGISENMAVPLMPDQQEEKLRSQL----EEEKRRYKTM 653
+ +Q L + + +P +++ K+ ++L EEE+ +++ +
Sbjct: 618 EAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPL 664
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 224 bits (570), Expect = 3e-58
Identities = 198/690 (28%), Positives = 329/690 (47%), Gaps = 86/690 (12%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
+ F R+F + QE V+ A + VLAGYNGTIFAYGQT SGKT T+ G
Sbjct: 47 YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
Query: 118 GIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
GIIPR IF + D + + +SY EIY + DLLD +++ E
Sbjct: 107 GIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKT--------NLSVHE 158
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
D ++ +K T ++ EE L+++ G +NR +A T MN+ S+RSH IF I++ +
Sbjct: 159 DKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENM 218
Query: 237 GSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIP 296
+ KL+LVDLAGSE+V+KTG G +L EAK IN SL L VI AL+E +S++P
Sbjct: 219 ETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVP 278
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S MT +L+DSLGGNC TTM S N E+ ST F QR IKN A +N E+
Sbjct: 279 YRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELT 338
Query: 357 PRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGA 416
K+ +KE ++ K ++ T A EAEL + ++ + +GA
Sbjct: 339 AEQWKKKYEKEKEKTK-------AQKETIAKLEAELSRWRNGENVPETERLAGEEAALGA 391
Query: 417 DMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEIN 476
+ L + + +N+++ ++ Q+ EEE R+L L +D+EIN
Sbjct: 392 E-------------LCEETPVNDNSSIVVRIAPEERQK--YEEEIRRLYKQLDDKDDEIN 436
Query: 477 ILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQR--MRLSSAPSQAQDF 534
+++K K++ +D+ E S G+ E+ QR L S A+D
Sbjct: 437 QQSQLIEKLKQQM--------LDQEELLVSTR-----GDNEKVQRELSHLQSENDAAKD- 482
Query: 535 SILGKRSSLLHKKIGMREEMSLGC-QEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALG 593
+ + + EE+++ Q++ E+ ++ + + +D+ L Q+ + +L
Sbjct: 483 --------EVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDE----LSQKVATMLSLE 530
Query: 594 ESINEARSKIGHLKEEITQ------RHIQQ--VALGISE-NMAVPLMPDQQEE------- 637
+ + GH ++ I + + + + V +G E + V + +EE
Sbjct: 531 SELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLY 590
Query: 638 --KLRSQLEEEKRRYKTM-------FTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAE 688
K++S+++ +R + + +++ E+ QLL+ + + K++ E +
Sbjct: 591 ISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSV 650
Query: 689 EATNLQVNSPAVNSLDHTKPFLQTSDSQHE 718
E + + +SL LQ ++ HE
Sbjct: 651 ELKKRHLEE-SYDSLSDELAKLQAQETVHE 679
Score = 40.4 bits (93), Expect = 0.007
Identities = 74/356 (20%), Positives = 147/356 (41%), Gaps = 64/356 (17%)
Query: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK 420
I+RL K++ + DE+ + Q E L + ++L E+L+ S D + R E+ +
Sbjct: 421 IRRLYKQLDDKDDEINQQS--QLIEKLKQ-QMLDQEELLVSTRGDNEKVQR-ELSHLQSE 476
Query: 421 VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQR-------DN 473
+K++L + LE V+ + K Q+ +E K ++ + L D L Q+ ++
Sbjct: 477 NDAAKDEVKEVL---QALEELAVNYDQKSQEVEE--KSQQNQLLVDELSQKVATMLSLES 531
Query: 474 EINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQD 533
E+ L + ++K+ E L+ D EF +GN E + +S A + +
Sbjct: 532 ELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVI------VGNGEIKLPVEISGAIEE--E 583
Query: 534 FSILGKRSSLLH-------KKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRF 586
F++ S + K+ E + + C E+ R+ + + ++ Q
Sbjct: 584 FTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRE------LSSCQLLISQHE 637
Query: 587 SEAKALGESINEARSKIGHLKEEI-----------TQRHIQQVALGISE---------NM 626
++ ++L E + K HL+E Q + +VAL E
Sbjct: 638 AKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKK 697
Query: 627 AVPLMPDQQEE-------KLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAK 675
A+ L + E +LR ++ E+++ + + L++E+E LQ +K K
Sbjct: 698 ALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLK 753
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 221 bits (564), Expect = 2e-57
Identities = 200/690 (28%), Positives = 327/690 (47%), Gaps = 61/690 (8%)
Query: 55 SYKFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERY 114
S + F R+F +QE V+ + AK + VL GYNGTIFAYGQT SGKT T+ G
Sbjct: 43 SKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP 102
Query: 115 SDRGIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVT 173
GIIPR + IF + D + + +SY EIY + DLLD ++
Sbjct: 103 EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT--------NLS 154
Query: 174 ILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSS 233
+ ED ++ ++K T + +E ++ + G +NR +A T MN+ S+RSH IF I++
Sbjct: 155 VHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQ 214
Query: 234 KEPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRS 293
+ + KL+LVDLAGSE+V+KTG G +L EAK IN SL L VI AL+E +
Sbjct: 215 ENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-GST 273
Query: 294 HIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNE 353
++PYR+S MT +L+DSLGGNC TT++ S N E+ ST F QR IKN +N
Sbjct: 274 YVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNV 333
Query: 354 EINPRLVIKRLQKE----------IQELKDEL-------AMVTGEQRTEALTEAELLQLE 396
E+ K+ +KE IQ L++EL + EQ + E ++
Sbjct: 334 ELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVD 393
Query: 397 KLITSFLEDQDSDSRLEVG----ADMRKVHHCFHHLKKLLNDK--KILENNTVSSESKDQ 450
K IT D+ + + +G A+ RK L K L+DK +I + + + + K Q
Sbjct: 394 KDIT-LTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQ 452
Query: 451 DCQEPLKEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMD---RREFRQSQ 507
+ R+ +D ++ N + + K+E K+ +AL ++ + + + +
Sbjct: 453 MLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDK 512
Query: 508 SPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKR 567
+ + L + E Q+ SA + D + + H+K E M+ ++ EI
Sbjct: 513 TKEYELLSDELNQK----SATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIA 568
Query: 568 DHADSVTIDDNKQILKQRFSEAKA-LGESINEARSKIGHLKE-EITQRHI-QQVALGISE 624
+ V + ++ + F+ A+ + + +E ++ + K+ E TQ +++ E
Sbjct: 569 VGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKE 628
Query: 625 NMAVPLMPDQQEEKLRS------QLEEEKRRYKTMFTRL-----------KALKVEIEHL 667
A L Q E K++S +E++KR+ + L K ++E EHL
Sbjct: 629 LAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHL 688
Query: 668 QLLMDKAKVKLQKEFEVWWAEEATNLQVNS 697
+ +VK E ++ E Q++S
Sbjct: 689 NKVQTANEVKQAVEQQIQSHRETHQKQISS 718
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 217 bits (553), Expect = 3e-56
Identities = 191/686 (27%), Positives = 315/686 (45%), Gaps = 74/686 (10%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
+ F R+ + QE V+ AK + VL GYNGTIFAYGQT SGKT T+ G
Sbjct: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
Query: 118 GIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
GIIPR IF+ + D + + +SY EIY + DLLD + + E
Sbjct: 107 GIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT--------NLAVHE 158
Query: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
D ++ ++K T ++ EE ++++ G NR +A T MN+ S+RSH IF I++ +
Sbjct: 159 DKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV 218
Query: 237 GSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIP 296
+ KL+LVDLAGSE+V+KTG G +L EAK IN SL L VI AL+E ++H+P
Sbjct: 219 ETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVP 278
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S MT +L+DSLGGNC TT++ S N E+ ST F QR IKN +N E+
Sbjct: 279 YRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELT 338
Query: 357 PRLVIKRLQKEIQELK------DELAMVTGEQRT-EALTEAELLQLEKLITSFLEDQDSD 409
K+ +KE ++ K L M R EA+ E E + +
Sbjct: 339 AEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAK------------- 385
Query: 410 SRLEVGADMRKVHHCFHHLKKLLNDKKILENNT-----VSSESKDQDCQEPLKEEEYRKL 464
D + + C ++ I++N +S+E K++ +EE L
Sbjct: 386 -------DQKNLEPC--------DNTPIIDNIAPVVAGISTEEKEK------YDEEISSL 424
Query: 465 RDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRL 524
L +D+EIN + +K K++ + L RR++ + Q RL E + +
Sbjct: 425 YRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEV 484
Query: 525 SSAPSQAQDFSI-LGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILK 583
++ ++ ++S + K E+++ E+ ++ + T + Q+ +
Sbjct: 485 KEVLQALEELAVNYDQKSQEVEDKTRANEQLT------DELAQKTTTLTTTQRELSQLQE 538
Query: 584 QRFSEAKALGESINEARSKIGHLKEEITQRHIQQVA--LGISENMAVPLMPDQQEEKLRS 641
+ K E +N +G + I ++ +A G+ E M K++S
Sbjct: 539 LSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFT--MARLYISKMKS 596
Query: 642 QLEEEKRRYKTMFT-------RLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQ 694
+++ R K + + ++ A + E+ QLL+ + + K++ + E Q
Sbjct: 597 EVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQ 656
Query: 695 VNSPAVNSLDHTKPFLQTSDSQHEWS 720
+ + +SL L+ + HE S
Sbjct: 657 LEE-SQDSLSEELAKLRAQEKMHEVS 681
Score = 35.0 bits (79), Expect = 0.28
Identities = 70/355 (19%), Positives = 158/355 (44%), Gaps = 48/355 (13%)
Query: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLED----QDSDSRLEVGA 416
I L +++ + DE+ + Q E L + ++L ++L+ S D Q+ +RL++
Sbjct: 421 ISSLYRQLDDKDDEINQQS--QLAEKLKQ-QMLDQDELLASTRRDYEKIQEELTRLQIEN 477
Query: 417 DMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQR----- 471
+ K +K++L + LE V+ + K Q+ ++ + E +L D L Q+
Sbjct: 478 EAAK-----DEVKEVL---QALEELAVNYDQKSQEVEDKTRANE--QLTDELAQKTTTLT 527
Query: 472 --DNEINILVNMLKKEKKKAQEALHLAGMDRREFRQ--SQSPPFRLGN-----PEEGQRM 522
E++ L + +KK+A E L+L D E + L + EE
Sbjct: 528 TTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMA 587
Query: 523 RLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQE--AFEIFKRDHADSV-TIDDNK 579
RL + +++ S++ + L ++ +M+ +E A ++ H + ++ D
Sbjct: 588 RLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYM 647
Query: 580 QILKQRFSEAKALGESINEARSKI------------GHLKEEITQ-RHIQQVALGISENM 626
Q ++Q+ + + +S++E +K+ KE +T+ + +++ + + M
Sbjct: 648 QNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQM 707
Query: 627 AVPLMPDQQE-EKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQK 680
Q++ +LR ++EE+++ + + L++E E L +K K++ Q+
Sbjct: 708 ESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQE 762
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 216 bits (549), Expect = 9e-56
Identities = 193/675 (28%), Positives = 326/675 (48%), Gaps = 78/675 (11%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGG--AERYS 115
F + +FD QE VF P+ V GYN T+ AYGQTGSGKT+++ G AE+ +
Sbjct: 49 FTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEN 108
Query: 116 DR--GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVT 173
+ G+IPR + +F+++ K S +T +SYLEIYNE DLL P E + ++
Sbjct: 109 EPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKA------QIN 162
Query: 174 ILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSS 233
I EDP + I + LT + ++ L G+ +R +A T MN S+RSH IFTI L
Sbjct: 163 IREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQ 222
Query: 234 KEPGSATVR-HAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE-KH 291
++ +KLHLVDLAGSER KT G L E IN L L VI AL + K
Sbjct: 223 RKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKK 282
Query: 292 RSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVL 351
+PYR+S +T +L+DSLGGN T MIA +S NL+E+++T R+A R IKN+ ++
Sbjct: 283 GGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIV 342
Query: 352 NEEINPRLV-IKRLQKEIQEL-----------------------------KDELAMVTGE 381
N I+P+ + L++++Q+L K++ + E
Sbjct: 343 N--IDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENE 400
Query: 382 QRTEALTEA---ELLQLEKLITSFLEDQDSDSRLEVGADMRKVHHCFHHLKKL---LNDK 435
+ + L+EA LE++I + ++ +++LE ++R+ C L+KL L D+
Sbjct: 401 KLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLE---ELRQHAACKLDLQKLVETLEDQ 457
Query: 436 KILENNTVSSESKDQDCQEPLKEEEYRKLR---DILKQRDNEINILVNMLK-KEKKKAQE 491
++ EN + + Q L +E + D +++ ++ + + Q
Sbjct: 458 ELKENVEIICNLQQLITQ--LSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQH 515
Query: 492 ALHLAGMDRR--EFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQD-FSILGKRSSLLHKKI 548
AL A M + E ++ + L +L Q QD L L K+
Sbjct: 516 ALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKE- 574
Query: 549 GMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKE 608
+EE+ L Q A K+D + + ++ L++ + L + +NE +SK+ LKE
Sbjct: 575 --KEELVLELQTA----KKDANQAKLSERRRKRLQELEGQIADLKKKLNE-QSKLLKLKE 627
Query: 609 EITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQ 668
T+R + ++ N + +M +Q+ + +R Q++E+ +++ + ++++
Sbjct: 628 S-TERTVSKL------NQEIRMMKNQRVQLMR-QMKEDAEKFRQWKQKKDKEVIQLKERD 679
Query: 669 LLMDKAKVKLQKEFE 683
+KL++ F+
Sbjct: 680 RKRQYELLKLERNFQ 694
Score = 38.9 bits (89), Expect = 0.019
Identities = 70/340 (20%), Positives = 157/340 (46%), Gaps = 40/340 (11%)
Query: 359 LVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSD--SRLEVGA 416
L + LQKE +EL EL + L+E +L++ LE Q +D +L +
Sbjct: 566 LEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQE-----LEGQIADLKKKLNEQS 620
Query: 417 DMRKVHHCFHH-LKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEI 475
+ K+ + KL + ++++N V + ++ E ++ + +K +++++ ++ +
Sbjct: 621 KLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDR 680
Query: 476 NILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFS 535
+LK E+ +++ L RR+ ++ + RL + + QR ++ + Q
Sbjct: 681 KRQYELLKLERNFQKQSNVL----RRKTEEAAAANKRLKDALQKQR-EVADKRKETQSRG 735
Query: 536 ILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQ---RFSEAKAL 592
+ G ++ + +G E+ + +EA KR D + ++++IL Q + E K
Sbjct: 736 MEG-TAARVKNWLGNEIEVMVSTEEA----KRHLNDLL---EDRKILAQDVAQLKEKKES 787
Query: 593 GE-----------SINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRS 641
GE S+ E R ++ ++ IT+ Q +L + D Q++ L +
Sbjct: 788 GENPPPKLRRRTFSLTEVRGQVSESEDSITK---QIESLETEMEFRSAQIADLQQKLLDA 844
Query: 642 QLEEE-KRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQK 680
+ E+ K+R++ + T L+A K +++L + +K+++ K
Sbjct: 845 ESEDRPKQRWENIATILEA-KCALKYLIGELVSSKIQVSK 883
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 214 bits (546), Expect = 2e-55
Identities = 168/523 (32%), Positives = 271/523 (51%), Gaps = 42/523 (8%)
Query: 4 QTIQIFARVKP-PVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQR 62
+ IQ+ R +P + + + +SI E + + + + G + +K + F
Sbjct: 17 KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSV------RTGGLADKSSRKTYTFDM 70
Query: 63 IFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGA---ERYSDR-- 117
+F Q V+ ++ P+ V+ GYN TIFAYGQTG+GKTFT+ G E Y+
Sbjct: 71 VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
Query: 118 ---GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTI 174
GIIPRTL IFE+L D+ ++ +S LEIYNE +DLL+P + S ++ +
Sbjct: 131 PLAGIIPRTLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE-----RLQM 184
Query: 175 LEDP--DQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLS 232
+DP + + +K L ++E +L G R A T MN S+RSH +F++ +
Sbjct: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIH 244
Query: 233 SKEP---GSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE 289
KE G V+ KL+LVDLAGSE + ++G EA IN SL L +VI AL E
Sbjct: 245 MKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE 304
Query: 290 KHRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEA 349
+ H+PYR S +T +L+DSLGG T++IAT+S NL+E++ST +A R I N+
Sbjct: 305 R-TPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 363
Query: 350 VLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSD 409
+N+++ + +IK +EI+ LK +LA E+ ++E + +T E+Q +
Sbjct: 364 EVNQKLTKKALIKEYTEEIERLKRDLA-AAREKNGVYISEENFRVMSGKLT-VQEEQIVE 421
Query: 410 SRLEVGA---DMRKVHHCFHHLKKLLND-KKILENNTVSSESKDQDCQE---PLKEEEYR 462
++GA ++ +V F K L+ K L+N T E+ + QE L +EEY
Sbjct: 422 LIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY- 480
Query: 463 KLRDILKQRDNEINILVNML---KKEKKKAQEALHLAGMDRRE 502
+ L+ + +++ + L +E K LH + +DR++
Sbjct: 481 -ITSALESTEEKLHDAASKLLNTVEETTKDVSGLH-SKLDRKK 521
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 213 bits (543), Expect = 4e-55
Identities = 186/669 (27%), Positives = 322/669 (48%), Gaps = 66/669 (9%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGG--AERYS 115
F + +FD QE VF P+ + GYN T+ AYGQTGSGKT+++ G AE+ +
Sbjct: 49 FTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEN 108
Query: 116 DR--GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVT 173
+ GIIPR + +F+++ K S +T +SYLEIYNE DLL P E + ++
Sbjct: 109 EPTVGIIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKA------QIN 162
Query: 174 ILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSS 233
I EDP + I + LT + ++ L G+ +R +A T MN S+RSH IFTI +
Sbjct: 163 IREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQ 222
Query: 234 KEPGSATVR-HAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE-KH 291
++ +KLHLVDLAGSER KT G L E IN L L VI AL + K
Sbjct: 223 RKKSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKK 282
Query: 292 RSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVL 351
S +PYR+S +T +L+DSLGGN T MIA +S NL+E++ST R+A R IKN+ ++
Sbjct: 283 GSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
Query: 352 NEEINPRLV-IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLI---TSFLEDQD 407
N I+P + L++++Q+L+ L G ++ L+ L+ S +E+ +
Sbjct: 343 N--IDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENE 400
Query: 408 SDSRL---EVGADMRKVHHCF--HHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYR 462
SR G + + + + LN K V+ + Q E L+++E +
Sbjct: 401 KLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELK 460
Query: 463 K-------LRDILKQRDNE----INILVNMLKKEKKK---------------AQEALHLA 496
+ L+ ++ Q +E ++ +E+ + Q ALH A
Sbjct: 461 ENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQA 520
Query: 497 GMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQ--DFSILGKRSSLLHKKIGMREEM 554
M + + + + E +++ +Q Q F +L + I +++E
Sbjct: 521 QMSKEVVELNNALALK-----EALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEK 575
Query: 555 SLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRH 614
+E + K++ + + ++L++ + L + +NE +SK+ LKE T+R
Sbjct: 576 EELVRE-LQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNE-QSKLLKLKES-TERT 632
Query: 615 IQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKA 674
+ ++ N + +M +Q+ + +R Q++E+ +++ + ++++
Sbjct: 633 VSKL------NQEIWMMKNQRVQLMR-QMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYE 685
Query: 675 KVKLQKEFE 683
+KL++ F+
Sbjct: 686 LLKLERNFQ 694
Score = 31.2 bits (69), Expect = 4.0
Identities = 54/329 (16%), Positives = 127/329 (38%), Gaps = 41/329 (12%)
Query: 363 RLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK-- 420
+L++ Q+ L T E + LQ ++ +T ++ S + + A +R
Sbjct: 688 KLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWL 747
Query: 421 ---------VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQR 471
HL LL D+KIL + V + K + + P + RK L +
Sbjct: 748 GNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENP--PPKLRKCTFSLSEV 805
Query: 472 DNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQA 531
++ + + K+ + + + L + +Q +L A S+
Sbjct: 806 HGQVLESEDCITKQIESLETEMELRSAQIADLQQ-----------------KLLDAESED 848
Query: 532 QDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKA 591
+ +++L K ++ + + K +++ + + K F E
Sbjct: 849 RPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNH 908
Query: 592 LGESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYK 651
E E ++++ ++ Q+H ++V +S+ + M ++Q EK S+ E++
Sbjct: 909 FSEIETELQAELVRME----QQHQEKVLYLVSQ-LQESQMAEKQLEKSASEKEQQ----- 958
Query: 652 TMFTRLKALKVEIEHLQLLMDKAKVKLQK 680
+ + L+ E+E ++ + ++ + LQ+
Sbjct: 959 -LVSTLQCQDEELEKMREVCEQNQQLLQE 986
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 211 bits (537), Expect = 2e-54
Identities = 145/418 (34%), Positives = 239/418 (57%), Gaps = 36/418 (8%)
Query: 6 IQIFARVKPPVRK----HQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKF- 60
+++ R++P R+ H + + +D ++ ++ + L + A G K +Y F
Sbjct: 6 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARG--QPKVFAYDHCFW 63
Query: 61 ---QRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
+ + ++ A Q+ VF+ + + + + GYN IFAYGQTGSGK++T+ G A++
Sbjct: 64 SMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQ---P 120
Query: 118 GIIPRTLSYIFEQLQKDSSK--IYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTIL 175
G+IPR S +FE+ QK+ ++ + +SY+EIYNE DLLDP+ +L+ +
Sbjct: 121 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLK------VR 174
Query: 176 EDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK- 234
E ++ L+ T+ ++ +L+ G+ +R +A T MN+ S+RSH +F I L+
Sbjct: 175 EHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTL 234
Query: 235 ---EPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKH 291
+ G++ + KL LVDLAGSER KTG G L E IN SL L VI AL+++
Sbjct: 235 YDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQS 294
Query: 292 -----RSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIK 346
+PYR+S++T +L+DSLGGN T M+AT+S N DE++ST R+A R I
Sbjct: 295 AGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIV 354
Query: 347 NEAVLNEEINPRLVIKRLQKEIQELKDEL----AMVTGEQRTEALTEAELLQLEKLIT 400
N AV+NE+ N R +I+ L++E+++L+++L AM + E + + L E+E L E +T
Sbjct: 355 NHAVVNEDPNAR-IIRDLREEVEKLREQLTKAEAMKSPELK-DRLEESEKLIQEMTVT 410
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 210 bits (535), Expect = 4e-54
Identities = 131/347 (37%), Positives = 209/347 (60%), Gaps = 24/347 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A QE VF+ + + + GYN IFAYGQTGSGK+F++ G AE+ G+IPR +
Sbjct: 73 AGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL---GLIPRLCCAL 129
Query: 128 FEQ--LQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
F++ L+++ S+ + +SY+EIYNE DLLDP+ SL+ + E ++
Sbjct: 130 FKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK------VREHKVLGPYVD 183
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
L+ T+ E+ +L+ G+ +R +A T MN+ S+RSH +F I ++ + G++
Sbjct: 184 GLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGE 243
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEK-----HRSHIP 296
+ +K+ LVDLAGSERV+KTG G L E IN SL L VI +L+++ +P
Sbjct: 244 KVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVP 303
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +L+D+LGGN T+MIAT+S N +E++ST R+A R I N AV+NE+ N
Sbjct: 304 YRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPN 363
Query: 357 PRLVIKRLQKEIQELKDELAM---VTGEQRTEALTEAELLQLEKLIT 400
+ VI+ L++E+++L+++L+ + + E L E+E L E +T
Sbjct: 364 AK-VIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVT 409
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 210 bits (535), Expect = 4e-54
Identities = 131/347 (37%), Positives = 209/347 (60%), Gaps = 24/347 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A QE VF+ + + + GYN IFAYGQTGSGK+F++ G AE+ G+IPR +
Sbjct: 73 AGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL---GLIPRLCCAL 129
Query: 128 FEQ--LQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
F++ L+++ S+ + +SY+EIYNE DLLDP+ SL+ + E ++
Sbjct: 130 FKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK------VREHKVLGPYVD 183
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
L+ T+ E+ +L+ G+ +R +A T MN+ S+RSH +F I ++ + G++
Sbjct: 184 GLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGE 243
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEK-----HRSHIP 296
+ +K+ LVDLAGSERV+KTG G L E IN SL L VI +L+++ +P
Sbjct: 244 KVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVP 303
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +L+D+LGGN T+MIAT+S N +E++ST R+A R I N AV+NE+ N
Sbjct: 304 YRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPN 363
Query: 357 PRLVIKRLQKEIQELKDELAM---VTGEQRTEALTEAELLQLEKLIT 400
+ VI+ L++E+++L+++L+ + + E L E+E L E +T
Sbjct: 364 AK-VIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVT 409
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 210 bits (535), Expect = 4e-54
Identities = 131/347 (37%), Positives = 209/347 (60%), Gaps = 24/347 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A QE VF+ + + + GYN IFAYGQTGSGK+F++ G AE+ G+IPR +
Sbjct: 73 AGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL---GLIPRLCCAL 129
Query: 128 FEQ--LQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
F++ L+++ S+ + +SY+EIYNE DLLDP+ SL+ + E ++
Sbjct: 130 FKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK------VREHKVLGPYVD 183
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
L+ T+ E+ +L+ G+ +R +A T MN+ S+RSH +F I ++ + G++
Sbjct: 184 GLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGE 243
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEK-----HRSHIP 296
+ +K+ LVDLAGSERV+KTG G L E IN SL L VI +L+++ +P
Sbjct: 244 KVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVP 303
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +L+D+LGGN T+MIAT+S N +E++ST R+A R I N AV+NE+ N
Sbjct: 304 YRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPN 363
Query: 357 PRLVIKRLQKEIQELKDELAM---VTGEQRTEALTEAELLQLEKLIT 400
+ VI+ L++E+++L+++L+ + + E L E+E L E +T
Sbjct: 364 AK-VIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVT 409
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 210 bits (535), Expect = 4e-54
Identities = 131/347 (37%), Positives = 209/347 (60%), Gaps = 24/347 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A QE VF+ + + + GYN IFAYGQTGSGK+F++ G AE+ G+IPR +
Sbjct: 73 AGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL---GLIPRLCCAL 129
Query: 128 FEQ--LQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
F++ L+++ S+ + +SY+EIYNE DLLDP+ SL+ + E ++
Sbjct: 130 FKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK------VREHKVLGPYVD 183
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
L+ T+ E+ +L+ G+ +R +A T MN+ S+RSH +F I ++ + G++
Sbjct: 184 GLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGNSGE 243
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEK-----HRSHIP 296
+ +K+ LVDLAGSERV+KTG G L E IN SL L VI +L+++ +P
Sbjct: 244 KVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVP 303
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +L+D+LGGN T+MIAT+S N +E++ST R+A R I N AV+NE+ N
Sbjct: 304 YRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPN 363
Query: 357 PRLVIKRLQKEIQELKDELAM---VTGEQRTEALTEAELLQLEKLIT 400
+ VI+ L++E+++L+++L+ + + E L E+E L E +T
Sbjct: 364 AK-VIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVT 409
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 204 bits (518), Expect = 3e-52
Identities = 146/456 (32%), Positives = 239/456 (52%), Gaps = 29/456 (6%)
Query: 49 VNNKRESYKFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTIT 108
+ + + KF F +FD+ + Q VFE+ KP+ S L GYN T+ AYG TG+GKT T+
Sbjct: 65 IKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
Query: 109 GGAERYSDRGIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLE 167
G A+ + G++ T+ ++++ + + KI +T +SYLE+YNE DL L
Sbjct: 125 GSAD---EPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDL---------LV 172
Query: 168 DLPKVTILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIF 227
+ + + ED + + + LTLHQ + EE L+LL G+ NR T MN S+RSH +F
Sbjct: 173 NSGPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVF 232
Query: 228 TIHLSSKEPGSA---TVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVI 284
I+L ++ ++ VR AK+ L+DLAGSER + +G G E IN SL L VI
Sbjct: 233 QIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVI 292
Query: 285 IALSEKHR--SHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRV 342
AL++ R HIPYRNS +T +L+DSLGGNC T MIA +S D++ +T ++A R
Sbjct: 293 NALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRA 352
Query: 343 ALIKNEAVLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSF 402
IK+ ++ + +N I + K E K E+ ++ +++ +A E + E
Sbjct: 353 KDIKS-SLKSNVLNVNNHITQYVKICNEQKAEILLL--KEKLKAYEEQKAFTNENDQAKL 409
Query: 403 LEDQDSDSRLEVGADMRKVHHC-FHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEY 461
+ + +E +++ +C F + +++ + LE +E K Q+ K+ E
Sbjct: 410 MISNPQEKEIE---RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEM 466
Query: 462 R----KLRDILKQRDNEINILVNMLKKEKKKAQEAL 493
K+ +RD+ + +L +K+ +E L
Sbjct: 467 MCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEEL 502
Score = 36.6 bits (83), Expect = 0.096
Identities = 75/351 (21%), Positives = 130/351 (37%), Gaps = 72/351 (20%)
Query: 457 KEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNP 516
K + Y + + + D ++ N +KE ++ QE L+ +R E RQ
Sbjct: 390 KLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQ----------- 438
Query: 517 EEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGM-----REEMSLGCQEAFEIFKRDHAD 571
E ++ + ++ + F HK+I M + E + G KRDH
Sbjct: 439 -EYLKLEMLLKENELKSFY-----QQQCHKQIEMMCSEDKVEKATG--------KRDHRL 484
Query: 572 SVTIDDNKQILKQRFSEAKALGESINEAR---------SKIGHLKEEITQR------HIQ 616
++ + K+R E K E+ N S+ GH+ +E+ + H+Q
Sbjct: 485 AMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQ 544
Query: 617 QVALG--ISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLK-------ALKVEIEHL 667
L I M + + +QQ + + L + + LK A + + + +
Sbjct: 545 NKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEI 604
Query: 668 QLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHEWSQLLSNKS 727
+ L+++ KV V WA++ P N L L T + S
Sbjct: 605 EHLVERKKV-------VVWADQTAE----QPKQNDLPGIS-VLMTFPQLGPVQPIPCCSS 652
Query: 728 SGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQ-SSTSTPLEDSIPK 777
SGG + T + RK++PSP H+ K S S L DS+ K
Sbjct: 653 SGGTNLVKIPTEKR-----TRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSK 698
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 200 bits (508), Expect = 5e-51
Identities = 182/709 (25%), Positives = 317/709 (44%), Gaps = 102/709 (14%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERY--- 114
F F +FD D+ QE ++ + + GYN T+FAYGQTG+GKT+T+ G +
Sbjct: 49 FTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVE 108
Query: 115 SDRGIIPRTLSYIFEQLQKDS---------SKIYTTHISYLEIYNECGYDLLDPRHEASS 165
+ GII R + ++F+ +++ + + + +LE+YNE DL D + +
Sbjct: 109 EELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDA 168
Query: 166 LEDLPKVTILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHC 225
+ I ED I+ +T TE E + L LG +R A T MN S+RSH
Sbjct: 169 KSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
Query: 226 IFTIHL---------------------SSKEPGSATVRHAKLHLVDLAGSERVAKTGVGG 264
IFTIH+ S + AK H VDLAGSER+ +TG G
Sbjct: 229 IFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATG 288
Query: 265 HLLTEAKYINLSLHYLEQVIIALSEKHR--SHIPYRNSMMTSVLRDSLGGNCMTTMIATL 322
E IN L L VI AL +K + +H+PYR+S +T +L+DSLGGN T MIA +
Sbjct: 289 ERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACV 348
Query: 323 SLEKRNLDESISTCRFAQRVALIKNEAVLN-----EEINP-RLVIKRLQKEIQELK---- 372
S R+ E+++T ++A R IKN+ ++N ++IN R I RLQ E+ E K
Sbjct: 349 SPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKR 408
Query: 373 --------------DELAMVTGEQ-----RTEALTEAELLQLEKLITSFLEDQDSDSRLE 413
E AM+ E R +A+ E + L IT + DQ +
Sbjct: 409 IIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQET-VDALRSRITQLVSDQANHVLAR 467
Query: 414 VGADMRKVHHCFHHLKKLLND--KKILENNTVSSESKDQDCQEPLKEEEY---RKLRDIL 468
G ++ + H K + D K+LE+ V+ + + + + +
Sbjct: 468 AGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTI 527
Query: 469 KQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAP 528
D E ++++ KK+ +K + R+E R+ +S + N + Q +
Sbjct: 528 LSSDKETIEIIDLAKKDLEK---------LKRKEKRKKKSVAGKEDNTDTDQEKKEEKGV 578
Query: 529 SQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQ---- 584
S+ ++ + + S + EE +E +I + +D + +++ Q
Sbjct: 579 SERENNELEVEESQEVSDHEDEEEEEE---EEEDDIDGGESSDESDSESDEKANYQADLA 635
Query: 585 ----RFSEAKALGESINEARSKIGHLKEE------ITQRHIQQVAL---GISENM-AVPL 630
+ + L + + ++ ++ LK++ + Q I+ L + +N+ +V
Sbjct: 636 NITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVES 695
Query: 631 MPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQ 679
+++ +K+RS+ E++ + RL+A + EH +LL ++++ + Q
Sbjct: 696 YSEEKAKKVRSEYEKKLQAMNKELQRLQA--AQKEHARLLKNQSQYEKQ 742
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 198 bits (504), Expect = 1e-50
Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 20/319 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A+Q V+ +I K + GYN IFAYGQTG+GK++T+ G E S GIIP+ +
Sbjct: 68 ASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEE-SQAGIIPQLCEEL 126
Query: 128 FEQLQKDSSK--IYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
FE++ + ++ Y+ +SY+EIY E DLL+P+++ + + + E P +++
Sbjct: 127 FEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGN-------LRVREHPLLGPYVE 179
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
+L+ T+ + +L+ G+ R +A T MN+ S+RSH +FTI + K E +T
Sbjct: 180 DLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTE 239
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE-----KHRSHIP 296
+ +K+ LVDLAGSER TG G L E IN SL L +VI AL+E K IP
Sbjct: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIP 299
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +LR++LGGN T M+A LS N DE++ST R+A R IK AV+NE+ N
Sbjct: 300 YRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPN 359
Query: 357 PRLVIKRLQKEIQELKDEL 375
+LV + L++E+ LKD L
Sbjct: 360 AKLV-RELKEEVTRLKDLL 377
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 198 bits (504), Expect = 1e-50
Identities = 126/319 (39%), Positives = 189/319 (59%), Gaps = 20/319 (6%)
Query: 68 ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYI 127
A+Q V+ +I K + GYN IFAYGQTG+GK++T+ G E S GIIP+ +
Sbjct: 68 ASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEE-SQAGIIPQLCEEL 126
Query: 128 FEQLQKDSSK--IYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLK 185
FE++ + ++ Y+ +SY+EIY E DLL+P+++ + + + E P +++
Sbjct: 127 FEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGN-------LRVREHPLLGPYVE 179
Query: 186 NLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSK----EPGSATV 241
+L+ T+ + +L+ G+ R +A T MN+ S+RSH +FTI + K E +T
Sbjct: 180 DLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTE 239
Query: 242 RHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE-----KHRSHIP 296
+ +K+ LVDLAGSER TG G L E IN SL L +VI AL+E K IP
Sbjct: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIP 299
Query: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
YR+S++T +LR++LGGN T M+A LS N DE++ST R+A R IK AV+NE+ N
Sbjct: 300 YRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPN 359
Query: 357 PRLVIKRLQKEIQELKDEL 375
+LV + L++E+ LKD L
Sbjct: 360 AKLV-RELKEEVTRLKDLL 377
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 198 bits (503), Expect = 2e-50
Identities = 159/505 (31%), Positives = 253/505 (50%), Gaps = 44/505 (8%)
Query: 6 IQIFARVKPPVRKHQQGIYSIDEDEKLIP-SLEIILPRDLADGFVNNKRESYKFKFQRIF 64
+++ R++P + K + +++ ++IP S ++I+ RD F F +F
Sbjct: 6 VKVAVRIRPLLCK--EALHNHQVCVRVIPNSQQVIIGRDRV------------FTFDFVF 51
Query: 65 DQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGG---AERYSDRGIIP 121
+++ Q+ V+ KP+ S++ GYN T+FAYGQTGSGKT+TI GG + +GIIP
Sbjct: 52 GKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIP 111
Query: 122 RTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQN 181
R + IF+ + + S + +SY+E+Y E DL D +S++DL I ED N
Sbjct: 112 RAIQEIFQSISEHPSIDFNVKVSYIEVYKE---DLRDLLELETSMKDL---HIREDEKGN 165
Query: 182 IHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTI-------HLSSK 234
+ + E ++LL +G+ R T MN+ S+RSH IFTI ++ +
Sbjct: 166 TVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAA 225
Query: 235 EPGS-ATVRH--AKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKH 291
E GS + RH +K H VDLAGSERV KTG G E+ IN L L VI AL +
Sbjct: 226 EDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPR 285
Query: 292 R--SHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEA 349
R SHIPYR++ +T +L+DSLGG+ T MI +S N DES+++ ++A R I+N+
Sbjct: 286 RKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKP 345
Query: 350 VLNEEINPRL-VIKRLQKEIQELKDEL-AMVTGEQRTEALTEAELLQLEKLITSFLEDQD 407
+N +P I ++ EI+ L++ L + G +T + ++ + LE+Q
Sbjct: 346 TVN--FSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHS--LEEQV 401
Query: 408 SDSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKE--EEYRKLR 465
+ + E V F L L + ++ E + QE K +R +
Sbjct: 402 AQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIG 461
Query: 466 DILKQRDNEINILVNMLKKEKKKAQ 490
+ ++ V LK+E KK Q
Sbjct: 462 GTASLEEGPQHVTVLQLKRELKKCQ 486
Score = 34.7 bits (78), Expect = 0.37
Identities = 59/341 (17%), Positives = 141/341 (41%), Gaps = 45/341 (13%)
Query: 359 LVIKRLQKEIQELKDELAMVTGE-QRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGAD 417
L + +L+ + ++ K EL + Q E +++ KL F + D+ ++L V
Sbjct: 759 LKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDA-AKLRVQV- 816
Query: 418 MRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRK--LRDILKQRDNEI 475
L+K D K L + ++ +E + + ++ + +Y+K L+ L++ + +
Sbjct: 817 ----------LQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKR 866
Query: 476 NILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFS 535
L ++K++++K +E G + G + + + + + F
Sbjct: 867 KQLDAVIKRDQQKIKEIQLKTGQEE-------------GLKPKAEDLDACNLKRRKGSFG 913
Query: 536 ILGKRSSLLHKKIGMREEMS--LGCQEAFEIFKRDHADSVTIDDNKQILKQ--------R 585
+ L +K + EE+ L ++ E + D I K+ L Q +
Sbjct: 914 SIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKK 973
Query: 586 FSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEE 645
++AL + +++ L++E++++++Q E + +Q E L+ + ++
Sbjct: 974 LRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKI----SEQVEVLQKEKDQ 1029
Query: 646 EKRRYKTMFTRLK---ALKVEIEHLQLLMDKAKVKLQKEFE 683
++R + +LK L E EH+ +++ L+ E
Sbjct: 1030 LQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIE 1070
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 197 bits (501), Expect = 3e-50
Identities = 143/397 (36%), Positives = 211/397 (53%), Gaps = 36/397 (9%)
Query: 5 TIQIFARVKPPVRKHQ----QGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKF 60
++++ RV+P R+ + + I +++ + I +L+I G K +Y F F
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 61 QRIFDQD---ANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
+ +QE VF+ + V S GYN +FAYGQTGSGK++T+ G + D
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNS---GDS 119
Query: 118 GIIPRTLSYIFEQLQKDS---SKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTI 174
G+IPR +F ++ + + + T +SYLEIYNE DLL R ++S +L +
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLL--RRKSSKTFNL---RV 174
Query: 175 LEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSS- 233
E P + ++++L+ H + L+ G+ NR A T MN S+RSH IFTI +
Sbjct: 175 REHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQA 234
Query: 234 ---KEPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE- 289
E TV +K+HLVDLAGSER TG G L E IN SL L VI AL++
Sbjct: 235 KFDSEMPCETV--SKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADL 292
Query: 290 ----------KHRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFA 339
K + +PYR+S++T +L+DSLGGN T MIAT+S N E++ST R+A
Sbjct: 293 SQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYA 352
Query: 340 QRVALIKNEAVLNEEINPRLVIKRLQKEIQELKDELA 376
R I N+ +NE+ N +L I+ L+ EI LK LA
Sbjct: 353 NRAKNIINKPTINEDANVKL-IRELRAEIARLKTLLA 388
Score = 38.5 bits (88), Expect = 0.025
Identities = 79/432 (18%), Positives = 177/432 (40%), Gaps = 50/432 (11%)
Query: 348 EAVLNEEINPRLVIKRLQKEIQELKDELAMVTGE-QRTEALTEAELLQLEKLITSFLEDQ 406
E + ++ + + ++R+Q+E++ + E +V + ++ E + +E + L ++
Sbjct: 617 EEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEK 676
Query: 407 DS--DSRLEVGADM-----RKVHHCFHHLKKLLNDKKILENNTVSSESK---DQDCQEPL 456
+ + RL ++ R+ F +++ L K L NN + + + + D +
Sbjct: 677 EKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKE 736
Query: 457 KEEEYRKL---RDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPF-- 511
K+E+Y KL + L++++ E +LV L+++ ++ QE + L ++ + +
Sbjct: 737 KDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEG 796
Query: 512 -----------RLGNPEEGQRMRLSSAP----SQAQDFSILGKRSSLLHKKIGMREEMSL 556
R G E+G+ + + + Q ++ L+ +K +++E+
Sbjct: 797 IRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQE 856
Query: 557 GCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEIT---QR 613
QE E K +H + + +E E I ++ + + ++ Q
Sbjct: 857 E-QEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQN 915
Query: 614 HI------QQVALGISENMAVPLMPDQ---QEEKLRSQLEEEKRRYKTMFTRLKALKVEI 664
H+ +Q A I + PL D Q EK + EE+ +Y+ +L+ L+
Sbjct: 916 HLPTLLEEKQRAFEILDRG--PLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATF 973
Query: 665 EHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQ----HEWS 720
E + + + +KE E+ + E + A+ L+ LQ + E
Sbjct: 974 EFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQR 1033
Query: 721 QLLSNKSSGGWE 732
Q L++ +SG E
Sbjct: 1034 QKLASLNSGSRE 1045
Score = 35.8 bits (81), Expect = 0.16
Identities = 71/328 (21%), Positives = 141/328 (42%), Gaps = 41/328 (12%)
Query: 364 LQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRKVHH 423
L+KE+QE ++ L + E E+ + + +T +D + +E ++
Sbjct: 850 LKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQL 909
Query: 424 CF---HHLKKLLNDKK----ILENNTVS------------SESKDQDCQEPLKEEEYRKL 464
+ +HL LL +K+ IL+ +S E ++Q Q + +KL
Sbjct: 910 QYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKL 969
Query: 465 R-------DILKQRDNEINILVNMLKKEKKKAQEALH--LAGMDRREFRQSQSPPFRLGN 515
+ +I +Q + +L+ +K+ +EAL LA ++RR + LG
Sbjct: 970 QATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHST--LGM 1027
Query: 516 PEEGQRMRLSSAPSQAQDFSIL-----GKRSSLLHKKIGMREEMSLGCQEAFEI--FKRD 568
E QR +L+S S +++ S L ++ +L + + E+ Q+ +E+ ++D
Sbjct: 1028 EIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKD 1087
Query: 569 HADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAV 628
H T++ S K+ + +AR +++EE+ QR +Q + ISE +
Sbjct: 1088 HHG--TLEGKVASSSLPVSAEKSHLVPLMDARIN-AYIEEEV-QRRLQDLHRVISEGCST 1143
Query: 629 PLMPDQQEEKLRSQLEEEKRRYKTMFTR 656
+ EKL + + K +Y+ M +R
Sbjct: 1144 SADTMKDNEKLHNGTIQRKLKYERMVSR 1171
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 197 bits (501), Expect = 3e-50
Identities = 135/403 (33%), Positives = 215/403 (53%), Gaps = 44/403 (10%)
Query: 5 TIQIFARVKPPVRKH----QQGIYSIDEDEKLIPSLEIILPRDLADGFVN---------- 50
T+Q+ RV+PP + ++ + + ++ L+ + P + GF
Sbjct: 7 TLQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFN-----PEEPDGGFPGLKWGGTHDGP 61
Query: 51 -NKRESYKFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITG 109
K + F F R+F + A Q+ VF++ V S L GYN ++FAYG TG+GKT T+ G
Sbjct: 62 KKKGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLG 121
Query: 110 GAERYSDRGIIPRTLSYIFEQLQ-KDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLED 168
R D GI+ T ++ +L+ + K + ISY E+YNE +DLL+P+
Sbjct: 122 ---REGDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGP------ 172
Query: 169 LPKVTILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFT 228
+ I EDPD+ + ++ L+ HQ + E+ L +L G+ NR T N S+RSH IF
Sbjct: 173 ---LAIREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQ 229
Query: 229 IHLSSKE--PG-SATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVII 285
I + ++ PG + V+ AK+ L+DLAGSER + T G L E IN SL L V+
Sbjct: 230 IFVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLN 289
Query: 286 ALSEK--HRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQ--- 340
AL++ ++H+PYR+S +T +L+DSLGGNC T MIA +S +++ +T ++A
Sbjct: 290 ALADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAK 349
Query: 341 --RVALIKNEAVLNEEINPRLVI-KRLQKEIQELKDELAMVTG 380
R++L N L+ I+ I ++LQ E+ L+ +L + G
Sbjct: 350 EIRLSLKSNVTSLDCHISQYATICQQLQAEVAALRKKLQVYEG 392
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 191 bits (484), Expect = 3e-48
Identities = 139/435 (31%), Positives = 224/435 (51%), Gaps = 47/435 (10%)
Query: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
+ F A+Q TV+E +A P+ G+N +FAYGQTGSGK++T+ G +E +
Sbjct: 408 WSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSE---EP 464
Query: 118 GIIPRTLSYIFEQLQKDSSKIYTTHI--SYLEIYNECGYDLLDPRHEASSLEDLPKVTIL 175
GIIPR +F Q+ + ++ + HI S+ E+YNE +DLL + E + + +
Sbjct: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQ--PLRVR 522
Query: 176 EDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKE 235
E P +++ L+++ ++ + + L LG+ R A T MN S+RSH +FT+ ++ +
Sbjct: 523 EHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTK 582
Query: 236 PGSATVRH------AKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSE 289
++++L+DLAGSER + G L E IN SL L +VI ALSE
Sbjct: 583 TEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSE 642
Query: 290 KHRSH---IPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIK 346
+ IPYR S++T +L++SLGGN T MIAT+S N++E++ST R+A + LI
Sbjct: 643 QANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIV 702
Query: 347 NEAVLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQ 406
N A +NE++N +L I+ELK E+A + QR + E +L
Sbjct: 703 NIAKVNEDMNAKL--------IRELKAEIAKLKAAQRNSRNIDPERYRL----------- 743
Query: 407 DSDSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRD 466
R E+ + K+H ++ + E V E +Q + L+E + +
Sbjct: 744 ---CRQEITSLRMKLHQ---------QERDMAEMQRVWKEKFEQAEKRKLQETKELQKAG 791
Query: 467 ILKQRDNEINILVNM 481
I+ Q DN + LVN+
Sbjct: 792 IMFQMDNHLPNLVNL 806
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,253,972
Number of Sequences: 37866
Number of extensions: 1350038
Number of successful extensions: 7799
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 6349
Number of HSP's gapped (non-prelim): 1358
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.