Guide to the Human Genome
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Search of human proteins with 157427667

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157427667 hypothetical protein LOC205147 [Homo sapiens]
         (861 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157427665 hypothetical protein LOC205147 [Homo sapiens]           1763   0.0  
gi|157427663 hypothetical protein LOC205147 [Homo sapiens]           1763   0.0  
gi|157427661 hypothetical protein LOC205147 [Homo sapiens]           1763   0.0  
gi|157427667 hypothetical protein LOC205147 [Homo sapiens]           1763   0.0  
gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]   112   1e-24
gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]    84   4e-16
gi|124244056 family with sequence similarity 123B [Homo sapiens]       79   1e-14
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      44   5e-04
gi|91208420 bassoon protein [Homo sapiens]                             44   8e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          42   0.002
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      41   0.005
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         41   0.005
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        41   0.005
gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]            40   0.007
gi|38373682 pleckstrin homology domain containing family G membe...    40   0.007
gi|111154084 pleckstrin homology domain containing family G memb...    40   0.007
gi|111154088 pleckstrin homology domain containing family G memb...    40   0.007
gi|111154080 pleckstrin homology domain containing family G memb...    40   0.007
gi|111154078 pleckstrin homology domain containing family G memb...    40   0.007
gi|6912492 mitogen-activated protein kinase 8 interacting protei...    40   0.007
gi|7706537 mitogen-activated protein kinase 8 interacting protei...    40   0.007
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      39   0.016
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    39   0.021
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    39   0.021
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    39   0.021
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    39   0.021
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    39   0.021

>gi|157427665 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 1763 bits (4567), Expect = 0.0
 Identities = 861/861 (100%), Positives = 861/861 (100%)

Query: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60
           MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ
Sbjct: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60

Query: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120
           EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS
Sbjct: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120

Query: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180
           PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE
Sbjct: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180

Query: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240
           GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS
Sbjct: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240

Query: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300
           LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ
Sbjct: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300

Query: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360
           NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS
Sbjct: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360

Query: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420
           GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD
Sbjct: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420

Query: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480
           ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS
Sbjct: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480

Query: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540
           QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP
Sbjct: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540

Query: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600
           TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS
Sbjct: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600

Query: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
           REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP
Sbjct: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660

Query: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720
           GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK
Sbjct: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720

Query: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780
           QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE
Sbjct: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780

Query: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840
           AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE
Sbjct: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840

Query: 841 GLLCGQPEVGASGPAMAEPHL 861
           GLLCGQPEVGASGPAMAEPHL
Sbjct: 841 GLLCGQPEVGASGPAMAEPHL 861


>gi|157427663 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 1763 bits (4567), Expect = 0.0
 Identities = 861/861 (100%), Positives = 861/861 (100%)

Query: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60
           MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ
Sbjct: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60

Query: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120
           EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS
Sbjct: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120

Query: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180
           PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE
Sbjct: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180

Query: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240
           GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS
Sbjct: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240

Query: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300
           LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ
Sbjct: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300

Query: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360
           NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS
Sbjct: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360

Query: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420
           GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD
Sbjct: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420

Query: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480
           ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS
Sbjct: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480

Query: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540
           QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP
Sbjct: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540

Query: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600
           TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS
Sbjct: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600

Query: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
           REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP
Sbjct: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660

Query: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720
           GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK
Sbjct: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720

Query: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780
           QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE
Sbjct: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780

Query: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840
           AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE
Sbjct: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840

Query: 841 GLLCGQPEVGASGPAMAEPHL 861
           GLLCGQPEVGASGPAMAEPHL
Sbjct: 841 GLLCGQPEVGASGPAMAEPHL 861


>gi|157427661 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 1763 bits (4567), Expect = 0.0
 Identities = 861/861 (100%), Positives = 861/861 (100%)

Query: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60
           MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ
Sbjct: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60

Query: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120
           EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS
Sbjct: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120

Query: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180
           PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE
Sbjct: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180

Query: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240
           GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS
Sbjct: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240

Query: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300
           LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ
Sbjct: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300

Query: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360
           NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS
Sbjct: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360

Query: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420
           GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD
Sbjct: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420

Query: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480
           ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS
Sbjct: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480

Query: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540
           QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP
Sbjct: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540

Query: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600
           TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS
Sbjct: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600

Query: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
           REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP
Sbjct: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660

Query: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720
           GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK
Sbjct: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720

Query: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780
           QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE
Sbjct: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780

Query: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840
           AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE
Sbjct: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840

Query: 841 GLLCGQPEVGASGPAMAEPHL 861
           GLLCGQPEVGASGPAMAEPHL
Sbjct: 841 GLLCGQPEVGASGPAMAEPHL 861


>gi|157427667 hypothetical protein LOC205147 [Homo sapiens]
          Length = 861

 Score = 1763 bits (4567), Expect = 0.0
 Identities = 861/861 (100%), Positives = 861/861 (100%)

Query: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60
           MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ
Sbjct: 1   MELKRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWSVLPGGQQRPHSEKGPQASPSAQ 60

Query: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120
           EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS
Sbjct: 61  EYDRCPNKGAQLDPKGGPAALCGATFKPVRKCKTHDSMSGAGRATAATGQLVGSASFPGS 120

Query: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180
           PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE
Sbjct: 121 PGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDLASLAAE 180

Query: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240
           GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS
Sbjct: 181 GKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVAS 240

Query: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300
           LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ
Sbjct: 241 LQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLASPAQ 300

Query: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360
           NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS
Sbjct: 301 NEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRS 360

Query: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420
           GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD
Sbjct: 361 GSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGD 420

Query: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480
           ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS
Sbjct: 421 ALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLS 480

Query: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540
           QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP
Sbjct: 481 QGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAP 540

Query: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600
           TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS
Sbjct: 541 TEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDAS 600

Query: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
           REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP
Sbjct: 601 REEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660

Query: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720
           GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK
Sbjct: 661 GHGGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQK 720

Query: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780
           QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE
Sbjct: 721 QSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEPTGLGVQAWASVEDQPLQLSTE 780

Query: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840
           AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE
Sbjct: 781 AVEQVAHGSQLDSEPRSAPAARWSSQGHHPESLGLTLNSQQEGGVSASAPECRCSLLARE 840

Query: 841 GLLCGQPEVGASGPAMAEPHL 861
           GLLCGQPEVGASGPAMAEPHL
Sbjct: 841 GLLCGQPEVGASGPAMAEPHL 861


>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
          Length = 671

 Score =  112 bits (281), Expect = 1e-24
 Identities = 131/459 (28%), Positives = 183/459 (39%), Gaps = 112/459 (24%)

Query: 4   KRGKTFIKSSLQVSHEKPPDPAAVAAAREGTGPWS--VLPGGQQRPHS---EKGPQASPS 58
           KRG   + S ++  H K  D  A A A EG  P    +LPG          E+ P+A+  
Sbjct: 191 KRGLRGLFSGMRW-HRK--DKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAARE 247

Query: 59  AQEYDRCPNKGAQLDPKGGPAA----LCGATFKPVRKCKTHDSMSGAGRATAATGQLVGS 114
            +E    P++ A  DP G PA        A   P R C+  + ++  G   A      G 
Sbjct: 248 PEE----PSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGH 303

Query: 115 ASFPGSPGSRRMIDYRHFVPQMPFVPAVAKSIPRKRISLKRPKKCFRNLFHIRRNKTEDL 174
                 PG  R  +       +P      K++P                           
Sbjct: 304 RRAEPGPGEVRTAEDASRTGAVP-----VKTVPL-------------------------- 332

Query: 175 ASLAAEGKSLPSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRAL 234
             + +EG S  +P  P DP      A + P   P  D +C                   +
Sbjct: 333 --VDSEGGSGRAPAAP-DP------ASVDPPSDPSADRIC------------------LM 365

Query: 235 CEDVASLQSFDSLTGCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQG 290
             DV SL+SFDSLTGCG++ AD  E + PS + +  GP  P      L  K P     QG
Sbjct: 366 FSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQG 420

Query: 291 SVEQLASPAQNEASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAEL 350
             E++ASP + + +    FWD ++++  Q      GP     +G  +  + L+T  + E 
Sbjct: 421 GGEEMASPDEVDDTYLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPET 472

Query: 351 PLCPCRDPRSGSKASSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPG 394
           P    R   +   ASS+                +   P+ EQ E V  SDEGY+DS +PG
Sbjct: 473 PK-DTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPG 531

Query: 395 LEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGP 433
            EED     S     A  PRDSYSGDALY+L+ DP   P
Sbjct: 532 PEED----SSSSGKKAGIPRDSYSGDALYDLYADPDGSP 566


>gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]
          Length = 552

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 69/205 (33%), Positives = 96/205 (46%), Gaps = 38/205 (18%)

Query: 249 GCGEVFAD--ESSVPSLELN-EGPESPTQAAQGLESKVPRG-PLQGSVEQLASPAQNEAS 304
           GCG++ AD  E + PS + +  GP  P      L  K P     QG  E++ASP + + +
Sbjct: 261 GCGDIIADQEEEAGPSCDKHVPGPGKPA-----LSKKNPGVVAYQGGGEEMASPDEVDDT 315

Query: 305 DFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKA 364
               FWD ++++  Q      GP     +G  +  + L+T  + E P    R   +   A
Sbjct: 316 YLQEFWDMLSQTEEQ------GP--EPQEGAAKVAAALETKVVPETPK-DTRCVEAAKDA 366

Query: 365 SSI----------------DTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTP 408
           SS+                +   P+ EQ E V  SDEGY+DS +PG EED     S    
Sbjct: 367 SSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEED----SSSSGK 422

Query: 409 AATFPRDSYSGDALYELFHDPSEGP 433
            A  PRDSYSGDALY+L+ DP   P
Sbjct: 423 KAGIPRDSYSGDALYDLYADPDGSP 447


>gi|124244056 family with sequence similarity 123B [Homo sapiens]
          Length = 1135

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 71/229 (31%), Positives = 90/229 (39%), Gaps = 44/229 (19%)

Query: 237 DVASLQSFDSLTGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLA 296
           DV SL+SFDSLTGCG++ A E  + S+  +           G +        QG  E++A
Sbjct: 315 DVTSLKSFDSLTGCGDIIA-EQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMA 373

Query: 297 SP-----------------------AQNEASDFTRFWDSVNRSVRQQQRALLGPWLS-GP 332
            P                        + E  D    W++     R        P  S G 
Sbjct: 374 LPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGH 433

Query: 333 QGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFS 392
            G           GLA   L                  TP+S+Q ES   SDEGYYDS +
Sbjct: 434 HGYMLLDPVRSYPGLAPGELL-----------------TPQSDQQESAPNSDEGYYDSTT 476

Query: 393 PGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDD 441
           PG E+D  EA          PRDSYSGDALYE F++P +      P DD
Sbjct: 477 PGFEDDSGEALGL-VRRDCLPRDSYSGDALYE-FYEPDDSLENSPPGDD 523


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 64/258 (24%), Positives = 78/258 (30%), Gaps = 41/258 (15%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
            PR  P       PPG  G P AP        G   + GG     AP  +     PG  G 
Sbjct: 793  PRGSPGERGETGPPGPAGFPGAP--------GQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 578  LAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPST 637
              G   A     QG           +  RG   G  ++    A       G N  P P  
Sbjct: 845  PGGSGPAGPPGPQGV----------KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894

Query: 638  WPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDA-EPMLAGCVARVAALKISSNEQPPAAWP 696
               S  + GPPG  G    P  PG  G   DA +P   G               P A  P
Sbjct: 895  PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG--------------SPGAQGP 940

Query: 697  PRQDMGSGLFGQRWARGPDMLEQKQSSSSPSMTTIHGLPYSASTQDQRCRDRVQDLSWLR 756
            P      G+ G   ARG         +  P M    G P     + +  +     LS  R
Sbjct: 941  PGAPGPLGIAGITGARG--------LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992

Query: 757  VEPTGLGVQAWASVEDQP 774
              P   G+   A    +P
Sbjct: 993  GPPGPQGLPGLAGTAGEP 1010



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 96/385 (24%), Positives = 122/385 (31%), Gaps = 79/385 (20%)

Query: 327  PWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEG 386
            P ++GP+G+  ++      G A  P  P ++   G K      G      P  V+    G
Sbjct: 788  PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGG 847

Query: 387  YYDSFSPGLEEDKKEAESPGTP-AATFP-RDSYSGDALYELFHDP--------SEGPLGP 436
               +  PG +  K E  SPG P AA FP      G         P         +GP GP
Sbjct: 848  SGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGP 907

Query: 437  SPDDDLCVSESLSGP--------------ALGT-----PLSICSFRVGAEENLAP----- 472
            + +     S  +SGP              A G      PL I     GA     P     
Sbjct: 908  AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI-TGARGLAGPPGMPG 966

Query: 473  ---APGPDLLSQGFLQSSWK-GKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPA 528
               +PGP    QG    S K G   L               S  R  P P+  P     A
Sbjct: 967  PRGSPGP----QGVKGESGKPGANGL---------------SGERGPPGPQGLPGLAGTA 1007

Query: 529  APPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLA--------G 580
              PG  G P   ++ L GR+G     G      +P       HPG  G +         G
Sbjct: 1008 GEPGRDGNP--GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 581  ESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG-KNKAPVPSTWP 639
            ES   G A       SR A   +  RG         +   T     +G K     P   P
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRG---------DKGETGERGAAGIKGHRGFPGN-P 1115

Query: 640  CSQKEPGPPGVLGCFRGPWRPGHGG 664
             +   PGP G  G    P   G  G
Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRG 1140



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 9/153 (5%)

Query: 512 LRRGPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAH 571
           LR G  P  P      A PPG  GA   P     G +G+  + GG         +     
Sbjct: 694 LRGGAGPPGPEGGKGAAGPPGPPGAAGTP-----GLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 572 PGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNK 631
           PG  G+   +     G T   G         ++  G + GL     +    +    G+  
Sbjct: 749 PGADGVPGKDGPR--GPTGPIGPPGPAGQPGDKGEGGAPGLPGI--AGPRGSPGERGETG 804

Query: 632 APVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGG 664
            P P+ +P +  + G PG  G    P   G GG
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837



 Score = 33.5 bits (75), Expect = 0.87
 Identities = 41/162 (25%), Positives = 55/162 (33%), Gaps = 15/162 (9%)

Query: 515 GPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGT 574
           G  P     PG+P  P G  GAP AP  K  G  G   + G   +  AP  +     PG 
Sbjct: 647 GGPPGENGKPGEPG-PKGDAGAPGAPGGK--GDAGAPGERGPPGLAGAPGLRGGAGPPGP 703

Query: 575 TGLL----------AGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTT 624
            G            A  +  L G     G L     + +  +G   G  +          
Sbjct: 704 EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD--KGEPGGPGADGVPGKDGPR 761

Query: 625 DTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDT 666
             +G    P P+  P  + E G PG+ G       PG  G+T
Sbjct: 762 GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGET 803



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 39/149 (26%), Positives = 48/149 (32%), Gaps = 13/149 (8%)

Query: 517 TPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTG 576
           +P  P + G+P  PPGSQG    P     G  G +   G   V   P  +     PG  G
Sbjct: 541 SPGGPGSDGKPG-PPGSQGESGRP-----GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594

Query: 577 LLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS 636
              G     G   QG        + E   +G         +   T      G    P   
Sbjct: 595 ERGGPG---GPGPQGPP----GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647

Query: 637 TWPCSQKEPGPPGVLGCFRGPWRPGHGGD 665
             P    +PG PG  G    P  PG  GD
Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGD 676



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 41/158 (25%), Positives = 52/158 (32%), Gaps = 12/158 (7%)

Query: 519 RAPPTPGQPAAPPGSQGAPRAPTEK-LGGREGLASDAGGATVCSAPS------RQELWAH 571
           R PP P      PG +G    P +    G  G   + G A +   P       +      
Sbjct: 413 RGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472

Query: 572 PGTTGL--LAGESKALG--GATQGTGTLS-RDASREEETRGHSEGLFSSMESAATSTTDT 626
           PG  GL   AGE  A G  G     G    +  + E    G +    ++ E         
Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532

Query: 627 SGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGG 664
            G    P     P S  +PGPPG  G    P  PG  G
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG 570



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 44/166 (26%), Positives = 54/166 (32%), Gaps = 28/166 (16%)

Query: 515 GPT-PRAPPT---PGQPAAPPGSQGAPRAPTEK-LGGREGLASDAGGATVCSAPSRQELW 569
           GP+ P  PP    P  PA   G  G P  P E+ L G  G+   AG       P    + 
Sbjct: 210 GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG------IPGFPGMK 263

Query: 570 AHPGTTGL-----------LAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMES 618
            H G  G            L GE+  L G     G +    +  E  R    G      +
Sbjct: 264 GHRGFDGRNGEKGETGAPGLKGEN-GLPGENGAPGPMGPRGAPGERGRPGLPG-----AA 317

Query: 619 AATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGG 664
            A       G +  P P   P +   PG PG  G       PG  G
Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNG 363



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 42/161 (26%), Positives = 50/161 (31%), Gaps = 26/161 (16%)

Query: 518 PRAPPTPGQ--PAAPPGSQGAPRAPTEK----------------LGGREGLASDAGGATV 559
           P +P   G+  PA  PGS GAP    E                 + G  G   + G A +
Sbjct: 344 PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGI 403

Query: 560 CSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESA 619
             AP        PG  G  A  +  L G     G     A  E   RG            
Sbjct: 404 PGAPGLMGARGPPGPAG--ANGAPGLRGGAGEPG--KNGAKGEPGPRGERGEAGIPGVPG 459

Query: 620 ATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
           A       G    P  +  P +  E G PG    FRGP  P
Sbjct: 460 AKGEDGKDGSPGEPGANGLPGAAGERGAPG----FRGPAGP 496


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 77/300 (25%), Positives = 108/300 (36%), Gaps = 63/300 (21%)

Query: 185  PSPGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELL---ADASFGLCRALCEDVASL 241
            P    P++PG    +AF P G   G   +      S L    AD+   L +     +A L
Sbjct: 3096 PGASYPAEPGLPNQQAFRPTGHYAGQTPM--PTTQSTLFPVPADSRAPLQKPRQTSLADL 3153

Query: 242  QSFDSLTGCGEVFADE----SSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLAS 297
            +    +    EV A      SS PS     GP   +   QG   +VPR   +GSV Q  +
Sbjct: 3154 EQ--KVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPA 3211

Query: 298  PAQNEASDFTRF------------------WDSVNRSVRQQQRALLGPWLSGPQGTDRDQ 339
            P     S +T                     DS + +   Q+   LGP  SG  G +  +
Sbjct: 3212 PTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGE 3271

Query: 340  SRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSP-GLEED 398
                  G+ + P  PC   R          G  +SE+            DS+ P G    
Sbjct: 3272 -----PGVLDGPTLPCCYAR----------GEEESEE------------DSYDPRGKGGH 3304

Query: 399  KKEAESPGTPAATFPRDSYSGDALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGTPLS 458
             +  ES G PA+T     Y GD+ Y   H       GP P      S+SL+  A+ +  S
Sbjct: 3305 LRSMESNGRPAST----HYYGDSDYR--HGARVEKYGPGPMGPKHPSKSLAPAAISSKRS 3358



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 95/383 (24%), Positives = 140/383 (36%), Gaps = 74/383 (19%)

Query: 283 VPRGPLQGSVEQL--------ASPAQNEASDFTRFWDSVNRS-------VRQQQRALLGP 327
           VP  P  G  E L        AS +    SD     D ++ S       V+Q+   L   
Sbjct: 652 VPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSA 711

Query: 328 WLSGPQGTDRDQSRLDTAGLAELPLCPCRD--PRSGSKASSIDTGTPKSEQPESVSTSDE 385
            ++GP       S +   G +  PL   +   P   SK  S  TG  + ++P S+S + E
Sbjct: 712 GVTGPHPPS--PSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPE 769

Query: 386 GYY--DSFSPGLEEDKKEAE------SPGTPAATFPRDSYSGDALYELFHDPSEGPLGPS 437
            +   +     LEED+  AE         T  ++   D +     ++   D SEG L P 
Sbjct: 770 AFDSDEELEDILEEDEDSAEWRRRREQQDTAESS---DDFGSQLRHDYVEDSSEGGLSPL 826

Query: 438 PDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKL 497
           P            PA    L+   F     + L  +   D L +    +S +G    L  
Sbjct: 827 PPQP---------PARAAELTDEDFM--RRQILEMSAEEDNLEEDDTATSGRG----LAK 871

Query: 498 CDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAPT--EKLGGREGLASDAG 555
             T+           + GP PR  P+  +PAA P  +    A T  E+L    G A    
Sbjct: 872 HGTQ-----------KGGPRPRPEPSQ-EPAALPKRRLPHNATTGYEELLPEGGSAEATD 919

Query: 556 GATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTG-TLSRD---------ASREEET 605
           G+       R+       +TG   G    LG   QG   +L R+          S E+ +
Sbjct: 920 GSGTLQGGLRRFKTIELNSTGSY-GHELDLG---QGPDPSLDREPELEMESLTGSPEDRS 975

Query: 606 RG-HSEGLFSSMESAATSTTDTS 627
           RG HS  L +S  S  + T+ TS
Sbjct: 976 RGEHSSTLPASTPSYTSGTSPTS 998



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 32/120 (26%), Positives = 46/120 (38%), Gaps = 7/120 (5%)

Query: 521 PPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAG 580
           PP PG P   PG    P + + +L  +E L    G     S   +Q     PG       
Sbjct: 58  PPVPG-PGPGPGPGPGPGSTSRRLDPKEPL----GNQRAASPTPKQASATTPGHES--PR 110

Query: 581 ESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPC 640
           E++A G A Q      R    +  T+        S +  +T T+  S    AP+PS+  C
Sbjct: 111 ETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLC 170



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 38/159 (23%), Positives = 52/159 (32%), Gaps = 21/159 (13%)

Query: 516  PTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTT 575
            P  + P TP   A  P   G PR       G    AS AG     S  S    + H  TT
Sbjct: 1373 PFSQGPGTPATTAVAPCPAGLPR-------GYMTPASPAGSERSPSPSSTAHSYGHSPTT 1425

Query: 576  GLLAGESKALGGATQGTGTLSRDASREEETRGHSEG----------LFSS----MESAAT 621
                 +++ L  A  G     R A  +  +    EG           F+S    +  ++ 
Sbjct: 1426 ANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSP 1485

Query: 622  STTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRP 660
            S + T    K    +T   S + P P       R P  P
Sbjct: 1486 SESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAP 1524



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 12/148 (8%)

Query: 510  SWLRRGPTPRAPPTPGQ-PAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQEL 568
            S+      P +P +P + P   PG  G PRA  E        A  +       AP+   +
Sbjct: 1471 SYFASSSPPLSPSSPSESPTFSPGKMG-PRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529

Query: 569  WAH-------PGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAAT 621
             A        P T  L+  ES     A     TL+ DAS +     H+    S + S   
Sbjct: 1530 VAQGTQTPHRPSTPRLVWQESSQ--EAPFMVITLASDASSQTRMV-HASASTSPLCSPTE 1586

Query: 622  STTDTSGKNKAPVPSTWPCSQKEPGPPG 649
            +   T G ++   PS      + PGPPG
Sbjct: 1587 TQPTTHGYSQTTPPSVSQLPPEPPGPPG 1614



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 33/97 (34%), Positives = 41/97 (42%), Gaps = 21/97 (21%)

Query: 515  GPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHP-G 573
            GP P  PP   Q     GS+G  +AP +   GR   A  A G      P+  +  A P G
Sbjct: 3830 GPQPAGPPRAEQ---TNGSKGTAKAPQQ---GRAPQAQPAPG----PGPAGVKAGARPGG 3879

Query: 574  TTGLLAGE---------SKAL-GGATQGTGTLSRDAS 600
            T G  AG+         SK L GGA +  G L+   S
Sbjct: 3880 TPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVS 3916


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 47/186 (25%), Positives = 63/186 (33%), Gaps = 23/186 (12%)

Query: 513  RRG-PTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAG------GATVCSAPSR 565
            R+G P P  PP P  P   PG +G P  P   + G +G   + G      G      P  
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425

Query: 566  QELWAHPGTTGLLA--GESKALGGATQGT-GTLSRDASREEE-------------TRGHS 609
              L   PG  G +   G+    G +  G  G   +  S  E+              RG  
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 610  EGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDA 669
              L  + E         +G    P  +  P ++   GPPG  G       PG  GD    
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 670  EPMLAG 675
             P +AG
Sbjct: 1546 GPAVAG 1551



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 56/208 (26%), Positives = 66/208 (31%), Gaps = 48/208 (23%)

Query: 516  PTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGR-EGLASDAGGATVCSAPSRQELWAHPGT 574
            P PR  P    P  P G    P AP + +GG   GL    G       P  +     PG 
Sbjct: 1331 PGPRGDPGERGPRGPKGE---PGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGP 1387

Query: 575  TGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPV 634
             G       A+ G     G        E    G  EG                    AP 
Sbjct: 1388 RGPPGLPGTAMKGDKGDRG--------ERGPPGPGEG------------------GIAPG 1421

Query: 635  PSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLAGCVARVAALKISSNEQ---- 690
                P     PGP G +G    P + G  GD+ D  P L G          S  EQ    
Sbjct: 1422 EPGLPGLPGSPGPQGPVG---PPGKKGEKGDSEDGAPGLPGQPG-------SPGEQGPRG 1471

Query: 691  PPAAWPPRQDMG----SGLFGQRWARGP 714
            PP A  P+ D G     G  G++  RGP
Sbjct: 1472 PPGAIGPKGDRGFPGPLGEAGEKGERGP 1499



 Score = 33.5 bits (75), Expect = 0.87
 Identities = 43/156 (27%), Positives = 50/156 (32%), Gaps = 40/156 (25%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
            P +P  PG P  P G  G   AP + + G  G   + G              A  G  G 
Sbjct: 2277 PGSPGLPG-PVGPKGEPGPTGAPGQAVVGLPGAKGEKG--------------APGGLAGD 2321

Query: 578  LAGESKALGG-ATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS 636
            L GE  A G     G      +A R  E     E                 G+  AP P 
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGE----------------DGQKGAPGPK 2365

Query: 637  TW--------PCSQKEPGPPGVLGCFRGPWRPGHGG 664
             +        P S   PGPPGV G    P  PG  G
Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 43/158 (27%), Positives = 54/158 (34%), Gaps = 29/158 (18%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEK----------------LGGREGLASDAGGATVCS 561
            P A   PG P +P G  G P    EK                + G  GL  + G      
Sbjct: 2589 PGAAGIPGDPGSP-GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAG 2647

Query: 562  APSRQELWAHPGTTGL--LAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESA 619
             P R  L  H G  G   + G+S    GA    G +     R  + +   +G     +  
Sbjct: 2648 PPGRPGLAGHKGEMGEPGVPGQS----GAPGKEGLIGPKGDRGFDGQPGPKG-----DQG 2698

Query: 620  ATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGP 657
                  T G    P PS    S   PGPPG +G  RGP
Sbjct: 2699 EKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP-RGP 2735



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 27/155 (17%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
            P+ PP    P  PPG QG P  P     G +G   + G       P  + L   PG+   
Sbjct: 1885 PQGPPGLPGPVGPPG-QGFPGVPGGT--GPKGDRGETGSKGEQGLPGERGLRGEPGSVPN 1941

Query: 578  LAGESKALGGATQGTGTLSRDASRE-EETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS 636
            +    +  G        +   A RE  ET   S G F  +          SG        
Sbjct: 1942 VDRLLETAG--------IKASALREIVETWDESSGSFLPVPERRRGPKGDSG-------- 1985

Query: 637  TWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEP 671
                   E GPPG  G    P   G  GD  D  P
Sbjct: 1986 -------EQGPPGKEGPIGFPGERGLKGDRGDPGP 2013



 Score = 30.0 bits (66), Expect = 9.6
 Identities = 53/213 (24%), Positives = 66/213 (30%), Gaps = 27/213 (12%)

Query: 519  RAPPTPGQPAAPPGSQGAPRAPTEKLG----GREGLASDAGGATVCSAPSRQELWAHPGT 574
            R PP P   A  PG  G P  P    G    GR G   + G         R      PGT
Sbjct: 2024 RGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGT 2083

Query: 575  TGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPV 634
             G        +     G G      S E+   G         +    S  D   K    V
Sbjct: 2084 PGPPGPPGPKVSVDEPGPG-----LSGEQGPPG-----LKGAKGEPGSNGDQGPKGDRGV 2133

Query: 635  PSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDT-LDAEPMLAGCVARVAALKISSNEQPPA 693
            P      + EPGP G  G    P  PG  G    + +P L G       +    +  PP 
Sbjct: 2134 PGI-KGDRGEPGPRGQDG---NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPG 2189

Query: 694  AWPPRQDMGSGLFGQRWARGPDMLEQKQSSSSP 726
            A         GL G    +GP  L+ +   + P
Sbjct: 2190 A--------PGLAGPAGPQGPSGLKGEPGETGP 2214


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 62/210 (29%), Positives = 78/210 (37%), Gaps = 32/210 (15%)

Query: 516 PTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTT 575
           P  R    P  PA P G+ GAP        G +G   DAG      AP  Q     PG  
Sbjct: 682 PGERGVQGPPGPAGPRGANGAP--------GNDGAKGDAGAP---GAPGSQ---GAPGLQ 727

Query: 576 GLLAGESKALG-----GATQGTGTLSRDASREEE-TRGHSEGLFSSMESAATSTTDTSGK 629
           G+  GE  A G     G     G    D S  ++  RG +  +     + A      SG 
Sbjct: 728 GM-PGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786

Query: 630 NKAPVPSTW---PCSQKEPGPPGVLGCFRGPWRPGHGGDT-LDAEPMLAGCVARVAALKI 685
           +    P+     P  + EPGPPG  G F GP  PG  G      EP  AG          
Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAG-FAGP--PGADGQPGAKGEPGDAGAKGDAGPPGP 843

Query: 686 SSNEQPPAAWPPRQDMGS-GLFGQRWARGP 714
           +    PP    P  ++G+ G  G R + GP
Sbjct: 844 AGPAGPPG---PIGNVGAPGAKGARGSAGP 870



 Score = 37.7 bits (86), Expect = 0.046
 Identities = 56/232 (24%), Positives = 74/232 (31%), Gaps = 47/232 (20%)

Query: 518 PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAP------SRQELWAH 571
           P  P  PG P  P G+ G P AP  K  G  G   + G   V   P       ++     
Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSK--GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGE 474

Query: 572 PGTTGLLAGESKALGGATQG-------------------TGTLSRDASREEETRGHSEGL 612
           PG TGL     +  G  ++G                    G      S  E  R    GL
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534

Query: 613 FSSME-SAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLG-----CFRGP----WRPGH 662
             +   + +  +    GK   P P+        PGPPG  G      F GP      PG 
Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594

Query: 663 GGDTLDAEPMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGP 714
            G+     P   G V        +  + PP          +G  G+R  +GP
Sbjct: 595 AGER--GVPGPPGAVGPAGKDGEAGAQGPPGP--------AGPAGERGEQGP 636



 Score = 37.0 bits (84), Expect = 0.079
 Identities = 42/186 (22%), Positives = 60/186 (32%), Gaps = 7/186 (3%)

Query: 488 WKGKECLLKLCDTELAITMGIV-SWLRRGPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGG 546
           WK + C + +CD    +   ++    +  P    P     P  P GS+      T  + G
Sbjct: 53  WKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEG 112

Query: 547 REGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETR 606
            +G     G       P R  +   PG  G              G          +E++ 
Sbjct: 113 PKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKST 172

Query: 607 GHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCF--RG-PWRPGHG 663
           G   G+        +      G   AP P  +     EPG PG  G    RG P  PG  
Sbjct: 173 G---GISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229

Query: 664 GDTLDA 669
           GD  +A
Sbjct: 230 GDDGEA 235



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 50/201 (24%), Positives = 59/201 (29%), Gaps = 15/201 (7%)

Query: 521 PPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLA- 579
           PP P   A PPG+ G P        G +G   DAG       P        PG  G +  
Sbjct: 807 PPGPAGFAGPPGADGQP--------GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858

Query: 580 -GESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTW 638
            G   A G A     T    A+      G S                  G      P+  
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918

Query: 639 PCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLAGCVARVAALKISSNEQ-----PPA 693
           P     PGPPG  G    P   G  G      P        V  L     E+     P  
Sbjct: 919 PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 694 AWPPRQDMGSGLFGQRWARGP 714
           +  P +   SG  G+R   GP
Sbjct: 979 SGEPGKQGPSGASGERGPPGP 999



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 57/237 (24%), Positives = 73/237 (30%), Gaps = 16/237 (6%)

Query: 516 PTPRAPPTPGQPAAPPGSQGAPRAPTEK-LGGREGLASDAGGATVCSAPSRQELWAHPGT 574
           P  R PP P      PG+ G P     +   G +G   DAG A     P        PG 
Sbjct: 241 PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ 300

Query: 575 TGL--LAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKA 632
            G   L GE +   GA    G    D +          G                   + 
Sbjct: 301 MGPRGLPGE-RGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQG 359

Query: 633 PVPSTWPCSQK-EPGPPGVLGCFRGPWRPGHGGDT----LDAEPMLAGCVARVAALKISS 687
           P  S  P   + EPGPPG  G       PG  G       +  P +AG      A   S 
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419

Query: 688 NEQPPAAWPPRQDMGSGLFGQRWARGPDMLEQKQSSSSPSMTTIHGLPYSASTQDQR 744
            + P    PP     SG  G   ++G        +   P    + G P  A  + +R
Sbjct: 420 PQGP--GGPPGPKGNSGEPGAPGSKG-----DTGAKGEPGPVGVQGPPGPAGEEGKR 469



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 56/200 (28%), Positives = 66/200 (33%), Gaps = 26/200 (13%)

Query: 519 RAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLL 578
           + PP P  PA   G QG   +P     G +GL   AG       P  Q +   PG  G  
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSP-----GFQGLPGPAGPPGEAGKPGEQGV---PGDLG-A 669

Query: 579 AGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTW 638
            G S A G          R    E   +G          + A       G   AP     
Sbjct: 670 PGPSGARG---------ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA--- 717

Query: 639 PCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLA-GCVARVAALKISSNEQPPAAWPP 697
           P SQ  PG  G+ G       PG  GD  DA P  A G   +     ++    PP     
Sbjct: 718 PGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777

Query: 698 RQDMG----SGLFGQRWARG 713
             D G    SG  G   ARG
Sbjct: 778 PGDKGESGPSGPAGPTGARG 797



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 23/157 (14%)

Query: 521 PPTPGQPAAPPGSQGA--------PRAPTEKLG-----GREGLASDAGGATVCSAPSRQE 567
           PP P  PA PPG  GA        P+ P    G     G  G    AG A     P    
Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD- 391

Query: 568 LWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTS 627
               PG  G  A  +  + GA    G  +R  S  +   G      +S E  A  +   +
Sbjct: 392 --GQPGAKG--ANGAPGIAGAPGFPG--ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT 445

Query: 628 GKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGG 664
           G    P P      Q  PGP G  G       PG  G
Sbjct: 446 GAKGEPGPVG---VQGPPGPAGEEGKRGARGEPGPTG 479



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 55/207 (26%), Positives = 66/207 (31%), Gaps = 32/207 (15%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
            P  PP P      PG+ G   AP     G  G    AG   V   P ++     PG  G 
Sbjct: 924  PPGPPGPAGEKGSPGADGPAGAP-----GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 578  LA-----GESKALG-----GATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTS 627
                   G S A G     G     G          E    +EG  S     +       
Sbjct: 979  SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEG--SPGRDGSPGAKGDR 1036

Query: 628  GKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLAGCVARVAALKISS 687
            G+     P   P +   PGP G  G      + G  G+T  A P  AG V  V A     
Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAG------KSGDRGETGPAGP--AGPVGPVGA----- 1083

Query: 688  NEQPPAAWPPRQDMG-SGLFGQRWARG 713
               P     PR D G +G  G R  +G
Sbjct: 1084 -RGPAGPQGPRGDKGETGEQGDRGIKG 1109



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 43/160 (26%), Positives = 50/160 (31%), Gaps = 13/160 (8%)

Query: 513  RRGPTPRAPPTPGQPAAPPGSQGAPRAP-TEKLGGREGLASDAGGATVCSAPSRQELWAH 571
            R  P P  PP    P    G +GAP A  +    G  G   D G       P        
Sbjct: 994  RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053

Query: 572  PGTTGLLA-----GESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDT 626
            PG  G        GE+   G A       +R  +  +  RG         +         
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF 1113

Query: 627  SGKNKAPVPSTWPCSQKEPGPPGVLGCF--RGPWRPGHGG 664
            SG    P P   P S  E GP G  G    RGP  PG  G
Sbjct: 1114 SGLQGPPGP---PGSPGEQGPSGASGPAGPRGP--PGSAG 1148



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 49/203 (24%), Positives = 64/203 (31%), Gaps = 23/203 (11%)

Query: 521  PPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGLLAG 580
            PP P  PA PPG  G   AP     G +G    AG       P        PG +G  AG
Sbjct: 840  PPGPAGPAGPPGPIGNVGAP-----GAKGARGSAGPPGATGFPGAAGRVGPPGPSG-NAG 893

Query: 581  ESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPC 640
                 G A +  G         +  RG +       E         +G+  +P       
Sbjct: 894  PPGPPGPAGKEGG---------KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 641  SQKEPGPPGVLGCFRGPWRPGHGGDT-LDAEPMLAGCVARVAALKISSNEQPPA------ 693
            +   PGP G+ G       PG  G+      P  +G   +      S    PP       
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 694  -AWPPRQDMGSGLFGQRWARGPD 715
             A PP +    G  G   + G D
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRD 1027


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 89/359 (24%), Positives = 134/359 (37%), Gaps = 43/359 (11%)

Query: 257 ESSVPSLELNEGPESPTQAAQGLESKVPRGPLQG---SVEQLASPAQNEA---SDFTRFW 310
           E+ V  +     P SP +  +     VP G L+    S+ Q +SP Q      +D     
Sbjct: 271 EAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEILNDTLEGV 330

Query: 311 DSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGSKASSIDTG 370
            SV+        +  G +L      +        AGLAE+P+    +    ++ASS+ TG
Sbjct: 331 HSVDGDPITDSGSGAGAFLDI---AEEKNLAATAAGLAEVPISTAGE----AEASSVPTG 383

Query: 371 TPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPA---ATFPRD-SYSGDALYELF 426
            P      ++S S E   +  +PG + +++ A +    A   A+ P +   SG A  EL 
Sbjct: 384 GP------TLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELD 437

Query: 427 HDPSEGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPG-----PDLLSQ 481
              S   LG          +SL+  A  T +S+ +F    E +  P  G       +  +
Sbjct: 438 LSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFE-DEEASGVPTDGLAPLTATMAPE 496

Query: 482 GFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAPT 541
             + S    +E L      E  IT G        P P  PP P    AP   +    A  
Sbjct: 497 RAVTSGPGDEEDLAAATTEEPLITAG--GEESGSPPPDGPPLPLPTVAP--ERWITPAQR 552

Query: 542 EKLG-----GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALG-GATQGTGT 594
           E +G     G +G   DAG       P   E     G T     E   LG G+  G+G+
Sbjct: 553 EHVGMKGQAGPKGEKGDAGE----ELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGS 607



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 133/580 (22%), Positives = 189/580 (32%), Gaps = 125/580 (21%)

Query: 188 GDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGLCRALCEDVASLQSFDSL 247
           GDP    G  + AFL             D+ + + LA  + GL           ++    
Sbjct: 335 GDPITDSGSGAGAFL-------------DIAEEKNLAATAAGLAEVPISTAGEAEASSVP 381

Query: 248 TGCGEVFADESSVPSLELNEGPESPTQAAQGLESKVPRGPLQGSVEQLAS-PAQNEASDF 306
           TG G   +  +  P   +  GP++  + A             G  E LAS P + EAS  
Sbjct: 382 TG-GPTLSMSTENPEEGVTPGPDNEERLA---------ATAAGEAEALASMPGEVEASGV 431

Query: 307 TRFWDSVNRSVRQQ-QRALLGPWLSGPQGT-------------DRDQSRLDTAGLAELP- 351
                 ++ S +   + A +GP       T             D + S + T GLA L  
Sbjct: 432 APGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTA 491

Query: 352 -LCPCRDPRSGSKASSIDTGTPKSEQP-------ESVSTSDEGY---YDSFSPGLEEDKK 400
            + P R   SG      D     +E+P       ES S   +G      + +P       
Sbjct: 492 TMAPERAVTSGP-GDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPA 550

Query: 401 EAESPGTPAATFPRDSYSGDALYELFHDPS-EGPLGPSPDDDLCVSESLSGPALGTPLSI 459
           + E  G      P+    GDA  EL   P   GP+GP+            G  LG    +
Sbjct: 551 QREHVGMKGQAGPKGE-KGDAGEELPGPPEPSGPVGPT------AGAEAEGSGLGWGSDV 603

Query: 460 CSFR---VGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGP 516
            S     VG+E+ L   PGP             G   +     T++ +          GP
Sbjct: 604 GSGSGDLVGSEQLLRGPPGPP---------GPPGLPGIPGKPGTDVFM----------GP 644

Query: 517 T-------PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELW 569
                   P   P P  P   PG  GA   P  K  G +G     G       P  + L 
Sbjct: 645 PGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMK--GEKGARGPNGSVGEKGDPGNRGLP 702

Query: 570 AHPGTTGLLAGESKALG-------------GATQGTGTLSRDASREEETRGHSEGLFSSM 616
             PG  G  AG    +G             G T G G        + E  G ++ L    
Sbjct: 703 GPPGKKG-QAGPPGVMGPPGPPGPPGPPGPGCTMGLG------FEDTEGSGSTQLLNEPK 755

Query: 617 ESAATSTTDTSGK--NKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLA 674
            S  T+     G+  ++ P            GPPG     RGP  PGH         +L+
Sbjct: 756 LSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGP----RGP--PGH-------IKVLS 802

Query: 675 GCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGP 714
             +  +    ++ ++ P    PP  D   GL G    RGP
Sbjct: 803 NSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 55/224 (24%), Positives = 73/224 (32%), Gaps = 43/224 (19%)

Query: 515  GPTPRAPPTPGQPAA--------PPGSQGAPRAPTEK----LGGREGLASDAGGATVCSA 562
            GP P  P  PG+P          PPG QG    P  K      G++G A + G A +   
Sbjct: 1332 GP-PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGG 1390

Query: 563  PSRQELWA------------HPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSE 610
            P +                 HPG  G     S  L G     G +      +   R    
Sbjct: 1391 PGKSGSMGPVGPPGPAGERGHPGAPG--PSGSPGLPGVPGSMGDMVNYDEIKRFIRQEII 1448

Query: 611  GLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAE 670
             +F    +  TS        +   P     +   PGPPG  G    P RPG  G      
Sbjct: 1449 KMFDERMAYYTS--------RMQFPMEMAAAPGRPGPPGKDG---APGRPGAPG-----S 1492

Query: 671  PMLAGCVARVAALKISSNEQPPAAWPPRQDMGSGLFGQRWARGP 714
            P L G + R     +      P     + D+G G+ G+    GP
Sbjct: 1493 PGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGP 1536



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 53/169 (31%), Positives = 62/169 (36%), Gaps = 46/169 (27%)

Query: 516  PTPRAPP-TPGQPAAP--PGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELW--- 569
            P P+ PP  PG P  P  PG QG P      L G+ GL ++ G     S P  Q L    
Sbjct: 903  PGPQGPPGIPGPPGPPGVPGLQGVP--GNNGLPGQPGLTAELG-----SLPIEQHLLKSI 955

Query: 570  ---------AHPGTTGLLAGESKALGGATQGTGT-------LSRDASREEETRG-HSEGL 612
                     AHPG   L+    K   G     G        LS +  R EE RG +SEG 
Sbjct: 956  CGDCVQGQRAHPGY--LVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEG- 1012

Query: 613  FSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPG 661
                           G    P P   P  + E GPPG+ G    P  PG
Sbjct: 1013 ----------DPGCVGSPGLPGPPGLPGQRGEEGPPGMRG---SPGPPG 1048



 Score = 33.9 bits (76), Expect = 0.66
 Identities = 51/187 (27%), Positives = 62/187 (33%), Gaps = 32/187 (17%)

Query: 515 GPTPRAPPTP-GQPAAP--PGSQG--APRAPTEKLGGREGLASDA-GGATVCSAPSRQEL 568
           GP  R    P G+P AP  PG QG   PR P    G +    S    GAT    P    +
Sbjct: 783 GPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASV 842

Query: 569 WAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG 628
              PG  G          G T   GT      R E+            E +  S  D   
Sbjct: 843 SGPPGRDGQQ--------GQTGLRGTPGEKGPRGEKGEPG--------ECSCPSQGDLIF 886

Query: 629 KNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPG-------HGGDTLDAEPMLAGCVARVA 681
                 P  W  S  +PGP G  G    P  PG        G + L  +P   G  A + 
Sbjct: 887 SGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQP---GLTAELG 943

Query: 682 ALKISSN 688
           +L I  +
Sbjct: 944 SLPIEQH 950



 Score = 33.9 bits (76), Expect = 0.66
 Identities = 42/151 (27%), Positives = 47/151 (31%), Gaps = 13/151 (8%)

Query: 516  PTPRAPPTPGQPAAPPGSQGAPRAP-TEKLGGREGLASDAGGATVCSAPSRQELWAHPGT 574
            P  R  P P  P  PPG  GA  +P    L G  GL    G       P +     +PG 
Sbjct: 1038 PGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQP---GYPGA 1094

Query: 575  TGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAA----TSTTDTSGKN 630
            TG        L G     G       + E     SEGL      A           SG+ 
Sbjct: 1095 TG-----PPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEK 1149

Query: 631  KAPVPSTWPCSQKEPGPPGVLGCFRGPWRPG 661
                    P     PGPPG  G    P  PG
Sbjct: 1150 GDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 36/154 (23%), Positives = 48/154 (31%), Gaps = 4/154 (2%)

Query: 518  PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
            P+  P P     PPG  G P        G +G     G   +   P +     HPG  G 
Sbjct: 1283 PQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPG- 1341

Query: 578  LAGESKALG--GATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVP 635
              G   A G  G     G       + +      +G       A          +  PV 
Sbjct: 1342 EPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVG 1401

Query: 636  STWPCSQK-EPGPPGVLGCFRGPWRPGHGGDTLD 668
               P  ++  PG PG  G    P  PG  GD ++
Sbjct: 1402 PPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVN 1435



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 67/273 (24%), Positives = 83/273 (30%), Gaps = 51/273 (18%)

Query: 518 PRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGLASDAGGATVCSAPSRQELWAHPGTTGL 577
           P   P P  P  P G +GA   P E       L    G   V + P        PG  G 
Sbjct: 609 PAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD--GDVRVVALPGPSGEKGEPGPPGF 666

Query: 578 -------LAGESKALG--------GATQGTGTLSRDASREEE-------TRGHSEGLFSS 615
                   AGE    G        G     GT  R     E         +G      ++
Sbjct: 667 GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTA 726

Query: 616 MESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLAG 675
             S   + TD +G+   P P      + E GP GV        RPG  G     +P L G
Sbjct: 727 CPSLQGTVTDMAGRPGQPGP------KGEQGPEGV-------GRPGKPG-----QPGLPG 768

Query: 676 CVARVAALKISSNEQPP--AAWPPRQDMGS-------GLFGQRWARGPDMLEQKQSSSSP 726
                    +     PP      P+ + G+       GL G R   GP   +  Q S   
Sbjct: 769 VQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGV 828

Query: 727 SMTTIHGLPYSASTQDQRCRDRVQDLSWLRVEP 759
              T    P  AS      RD  Q  + LR  P
Sbjct: 829 KGATGPVGPPGASVSGPPGRDGQQGQTGLRGTP 861


>gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 35/210 (16%)

Query: 455 TPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRR 514
           TP ++CS R GA   +AP PG     +  ++ +     C   LC     + MG+      
Sbjct: 757 TPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPC--ALCGKGSQVGMGVA----- 809

Query: 515 GPTPRAPPTPGQPAAPPGSQGAPRAPTE----KLGGR--EGLASDAGGATVCSAPSRQEL 568
                  PTPG         G   APT     ++G R   G+A  AG      +P R+ +
Sbjct: 810 -------PTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAV 862

Query: 569 WAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG 628
              PGT            G+T   G L  D S   +    + G   S  S A        
Sbjct: 863 APTPGTLHCDGSRKCTATGST--PGALPGDRSGVSKATAPAPGALCSERSRAR------- 913

Query: 629 KNKAPVP------STWPCSQKEPGPPGVLG 652
           ++ AP P       +W      P P  +LG
Sbjct: 914 RSIAPTPCLLCGDRSWVGMGIAPTPGALLG 943



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 40/324 (12%)

Query: 338  DQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQ--------PESVSTSDEGYYD 389
            D+SR  TA +   P   C D    S+A +   GT  SE+        P   +   +G   
Sbjct: 746  DRSRELTA-IDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQV 804

Query: 390  SF----SPG-LEEDKKEAESP--GTPAATFPRDSYSGDALY----ELFHD--PSEGPLGP 436
                  +PG L  D+ +A      TP+A F   S  G  +      L  D  P    + P
Sbjct: 805  GMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAVAP 864

Query: 437  SPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLK 496
            +P    C           TP ++   R G  +  APAPG     +   + S     CL  
Sbjct: 865  TPGTLHCDGSRKCTATGSTPGALPGDRSGVSKATAPAPGALCSERSRARRSIAPTPCL-- 922

Query: 497  LCDTELAITMGIV---SWLRRGPTPRAPPTPGQPAAPPGSQGAPR---APTEKLGGREG- 549
            LC     + MGI      L  G + +       P A  G +   R   APT +    +G 
Sbjct: 923  LCGDRSWVGMGIAPTPGALLGGKSRKCRAIAITPGALRGGRSQKRRVVAPTPEALHGDGS 982

Query: 550  -----LASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGT-GTLSRDASREE 603
                 +A   G     S+P+   +   PG    L G+      A   T GTL  DAS   
Sbjct: 983  WTYMAIAPTPGALHGDSSPAHTSIIPSPGA---LHGDGPPAHMAFPSTPGTLHGDASHAH 1039

Query: 604  ETRGHSEGLFSSMESAATSTTDTS 627
                 + G      S A + T  S
Sbjct: 1040 MAIAPTPGTMRGDSSTARTATAPS 1063


>gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 35/210 (16%)

Query: 455 TPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRR 514
           TP ++CS R GA   +AP PG     +  ++ +     C   LC     + MG+      
Sbjct: 757 TPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPC--ALCGKGSQVGMGVA----- 809

Query: 515 GPTPRAPPTPGQPAAPPGSQGAPRAPTE----KLGGR--EGLASDAGGATVCSAPSRQEL 568
                  PTPG         G   APT     ++G R   G+A  AG      +P R+ +
Sbjct: 810 -------PTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAV 862

Query: 569 WAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG 628
              PGT            G+T   G L  D S   +    + G   S  S A        
Sbjct: 863 APTPGTLHCDGSRKCTATGST--PGALPGDRSGVSKATAPAPGALCSERSRAR------- 913

Query: 629 KNKAPVP------STWPCSQKEPGPPGVLG 652
           ++ AP P       +W      P P  +LG
Sbjct: 914 RSIAPTPCLLCGDRSWVGMGIAPTPGALLG 943



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 40/324 (12%)

Query: 338  DQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQ--------PESVSTSDEGYYD 389
            D+SR  TA +   P   C D    S+A +   GT  SE+        P   +   +G   
Sbjct: 746  DRSRELTA-IDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQV 804

Query: 390  SF----SPG-LEEDKKEAESP--GTPAATFPRDSYSGDALY----ELFHD--PSEGPLGP 436
                  +PG L  D+ +A      TP+A F   S  G  +      L  D  P    + P
Sbjct: 805  GMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAVAP 864

Query: 437  SPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLK 496
            +P    C           TP ++   R G  +  APAPG     +   + S     CL  
Sbjct: 865  TPGTLHCDGSRKCTATGSTPGALPGDRSGVSKATAPAPGALCSERSRARRSIAPTPCL-- 922

Query: 497  LCDTELAITMGIV---SWLRRGPTPRAPPTPGQPAAPPGSQGAPR---APTEKLGGREG- 549
            LC     + MGI      L  G + +       P A  G +   R   APT +    +G 
Sbjct: 923  LCGDRSWVGMGIAPTPGALLGGKSRKCRAIAITPGALRGGRSQKRRVVAPTPEALHGDGS 982

Query: 550  -----LASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGT-GTLSRDASREE 603
                 +A   G     S+P+   +   PG    L G+      A   T GTL  DAS   
Sbjct: 983  WTYMAIAPTPGALHGDSSPAHTSIIPSPGA---LHGDGPPAHMAFPSTPGTLHGDASHAH 1039

Query: 604  ETRGHSEGLFSSMESAATSTTDTS 627
                 + G      S A + T  S
Sbjct: 1040 MAIAPTPGTMRGDSSTARTATAPS 1063


>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2028

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 35/210 (16%)

Query: 455 TPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRR 514
           TP ++CS R GA   +AP PG     +  ++ +     C   LC     + MG+      
Sbjct: 725 TPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPC--ALCGKGSQVGMGVA----- 777

Query: 515 GPTPRAPPTPGQPAAPPGSQGAPRAPTE----KLGGR--EGLASDAGGATVCSAPSRQEL 568
                  PTPG         G   APT     ++G R   G+A  AG      +P R+ +
Sbjct: 778 -------PTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAV 830

Query: 569 WAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG 628
              PGT            G+T   G L  D S   +    + G   S  S A        
Sbjct: 831 APTPGTLHCDGSRKCTATGST--PGALPGDRSGVSKATAPAPGALCSERSRAR------- 881

Query: 629 KNKAPVP------STWPCSQKEPGPPGVLG 652
           ++ AP P       +W      P P  +LG
Sbjct: 882 RSIAPTPCLLCGDRSWVGMGIAPTPGALLG 911



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 40/324 (12%)

Query: 338  DQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQ--------PESVSTSDEGYYD 389
            D+SR  TA +   P   C D    S+A +   GT  SE+        P   +   +G   
Sbjct: 714  DRSRELTA-IDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQV 772

Query: 390  SF----SPG-LEEDKKEAESP--GTPAATFPRDSYSGDALY----ELFHD--PSEGPLGP 436
                  +PG L  D+ +A      TP+A F   S  G  +      L  D  P    + P
Sbjct: 773  GMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAVAP 832

Query: 437  SPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLK 496
            +P    C           TP ++   R G  +  APAPG     +   + S     CL  
Sbjct: 833  TPGTLHCDGSRKCTATGSTPGALPGDRSGVSKATAPAPGALCSERSRARRSIAPTPCL-- 890

Query: 497  LCDTELAITMGIV---SWLRRGPTPRAPPTPGQPAAPPGSQGAPR---APTEKLGGREG- 549
            LC     + MGI      L  G + +       P A  G +   R   APT +    +G 
Sbjct: 891  LCGDRSWVGMGIAPTPGALLGGKSRKCRAIAITPGALRGGRSQKRRVVAPTPEALHGDGS 950

Query: 550  -----LASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGT-GTLSRDASREE 603
                 +A   G     S+P+   +   PG    L G+      A   T GTL  DAS   
Sbjct: 951  WTYMAIAPTPGALHGDSSPAHTSIIPSPGA---LHGDGPPAHMAFPSTPGTLHGDASHAH 1007

Query: 604  ETRGHSEGLFSSMESAATSTTDTS 627
                 + G      S A + T  S
Sbjct: 1008 MAIAPTPGTMRGDSSTARTATAPS 1031


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 35/210 (16%)

Query: 455 TPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRR 514
           TP ++CS R GA   +AP PG     +  ++ +     C   LC     + MG+      
Sbjct: 631 TPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPC--ALCGKGSQVGMGVA----- 683

Query: 515 GPTPRAPPTPGQPAAPPGSQGAPRAPTE----KLGGR--EGLASDAGGATVCSAPSRQEL 568
                  PTPG         G   APT     ++G R   G+A  AG      +P R+ +
Sbjct: 684 -------PTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAV 736

Query: 569 WAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSG 628
              PGT            G+T   G L  D S   +    + G   S  S A        
Sbjct: 737 APTPGTLHCDGSRKCTATGST--PGALPGDRSGVSKATAPAPGALCSERSRAR------- 787

Query: 629 KNKAPVP------STWPCSQKEPGPPGVLG 652
           ++ AP P       +W      P P  +LG
Sbjct: 788 RSIAPTPCLLCGDRSWVGMGIAPTPGALLG 817



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 81/324 (25%), Positives = 113/324 (34%), Gaps = 40/324 (12%)

Query: 338 DQSRLDTAGLAELPLCPCRDPRSGSKASSIDTGTPKSEQ--------PESVSTSDEGYYD 389
           D+SR  TA +   P   C D    S+A +   GT  SE+        P   +   +G   
Sbjct: 620 DRSRELTA-IDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQV 678

Query: 390 SF----SPG-LEEDKKEAESP--GTPAATFPRDSYSGDALY----ELFHD--PSEGPLGP 436
                 +PG L  D+ +A      TP+A F   S  G  +      L  D  P    + P
Sbjct: 679 GMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAVAP 738

Query: 437 SPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLK 496
           +P    C           TP ++   R G  +  APAPG     +   + S     CL  
Sbjct: 739 TPGTLHCDGSRKCTATGSTPGALPGDRSGVSKATAPAPGALCSERSRARRSIAPTPCL-- 796

Query: 497 LCDTELAITMGIV---SWLRRGPTPRAPPTPGQPAAPPGSQGAPR---APTEKLGGREG- 549
           LC     + MGI      L  G + +       P A  G +   R   APT +    +G 
Sbjct: 797 LCGDRSWVGMGIAPTPGALLGGKSRKCRAIAITPGALRGGRSQKRRVVAPTPEALHGDGS 856

Query: 550 -----LASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGT-GTLSRDASREE 603
                +A   G     S+P+   +   PG    L G+      A   T GTL  DAS   
Sbjct: 857 WTYMAIAPTPGALHGDSSPAHTSIIPSPGA---LHGDGPPAHMAFPSTPGTLHGDASHAH 913

Query: 604 ETRGHSEGLFSSMESAATSTTDTS 627
                + G      S A + T  S
Sbjct: 914 MAIAPTPGTMRGDSSTARTATAPS 937


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 35/298 (11%)

Query: 372 PKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSE 431
           P S+QP      +E   +      EE+++E E  GT AA+ P          +  H  S+
Sbjct: 695 PGSQQPLQSLEEEEDEQEEEEEE-EEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASD 753

Query: 432 GPLGPSPDDDLCVSESLSGPALGT-PLSICSFRVGAEENLAPA-PGPDLLSQGFLQSSWK 489
           G         +   ++LS P   + P S  S         + A P  +LL  G +     
Sbjct: 754 GSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD---- 809

Query: 490 GKECLLKLCDTELAITMGIVSWLRRGP----TPRAPPTPGQPAAPPGSQGAPRAPTEKLG 545
           G+ C +      L+ T  +  ++  GP     PRAP +P  P+ PP  +   R P + L 
Sbjct: 810 GRSCSMDSAYGTLSPT-SLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLS 868

Query: 546 GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKAL----------GGATQGTGTL 595
               L      A++       +L A  GT G  +  S++L          G  TQG+   
Sbjct: 869 CPPHLLKSKSEASLL------QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQE 922

Query: 596 SRDA--SREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS-TWPCSQKEPGPPGV 650
           +  +   R   + G   GL   +   A     +  K    +PS   P  Q EP PPGV
Sbjct: 923 AGPSWDCRGAPSPGSGPGLVGCL---AGEPAGSHRKRCGDLPSGASPRVQPEP-PPGV 976


>gi|111154084 pleckstrin homology domain containing family G member 5
            isoform b [Homo sapiens]
          Length = 1083

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 35/298 (11%)

Query: 372  PKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSE 431
            P S+QP      +E   +      EE+++E E  GT AA+ P          +  H  S+
Sbjct: 772  PGSQQPLQSLEEEEDEQEEEEEE-EEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASD 830

Query: 432  GPLGPSPDDDLCVSESLSGPALGT-PLSICSFRVGAEENLAPA-PGPDLLSQGFLQSSWK 489
            G         +   ++LS P   + P S  S         + A P  +LL  G +     
Sbjct: 831  GSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD---- 886

Query: 490  GKECLLKLCDTELAITMGIVSWLRRGP----TPRAPPTPGQPAAPPGSQGAPRAPTEKLG 545
            G+ C +      L+ T  +  ++  GP     PRAP +P  P+ PP  +   R P + L 
Sbjct: 887  GRSCSMDSAYGTLSPT-SLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLS 945

Query: 546  GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKAL----------GGATQGTGTL 595
                L      A++       +L A  GT G  +  S++L          G  TQG+   
Sbjct: 946  CPPHLLKSKSEASLL------QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQE 999

Query: 596  SRDA--SREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS-TWPCSQKEPGPPGV 650
            +  +   R   + G   GL   +   A     +  K    +PS   P  Q EP PPGV
Sbjct: 1000 AGPSWDCRGAPSPGSGPGLVGCL---AGEPAGSHRKRCGDLPSGASPRVQPEP-PPGV 1053


>gi|111154088 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 35/298 (11%)

Query: 372 PKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSE 431
           P S+QP      +E   +      EE+++E E  GT AA+ P          +  H  S+
Sbjct: 695 PGSQQPLQSLEEEEDEQEEEEEE-EEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASD 753

Query: 432 GPLGPSPDDDLCVSESLSGPALGT-PLSICSFRVGAEENLAPA-PGPDLLSQGFLQSSWK 489
           G         +   ++LS P   + P S  S         + A P  +LL  G +     
Sbjct: 754 GSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD---- 809

Query: 490 GKECLLKLCDTELAITMGIVSWLRRGP----TPRAPPTPGQPAAPPGSQGAPRAPTEKLG 545
           G+ C +      L+ T  +  ++  GP     PRAP +P  P+ PP  +   R P + L 
Sbjct: 810 GRSCSMDSAYGTLSPT-SLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLS 868

Query: 546 GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKAL----------GGATQGTGTL 595
               L      A++       +L A  GT G  +  S++L          G  TQG+   
Sbjct: 869 CPPHLLKSKSEASLL------QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQE 922

Query: 596 SRDA--SREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS-TWPCSQKEPGPPGV 650
           +  +   R   + G   GL   +   A     +  K    +PS   P  Q EP PPGV
Sbjct: 923 AGPSWDCRGAPSPGSGPGLVGCL---AGEPAGSHRKRCGDLPSGASPRVQPEP-PPGV 976


>gi|111154080 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 35/298 (11%)

Query: 372 PKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSE 431
           P S+QP      +E   +      EE+++E E  GT AA+ P          +  H  S+
Sbjct: 695 PGSQQPLQSLEEEEDEQEEEEEE-EEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASD 753

Query: 432 GPLGPSPDDDLCVSESLSGPALGT-PLSICSFRVGAEENLAPA-PGPDLLSQGFLQSSWK 489
           G         +   ++LS P   + P S  S         + A P  +LL  G +     
Sbjct: 754 GSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD---- 809

Query: 490 GKECLLKLCDTELAITMGIVSWLRRGP----TPRAPPTPGQPAAPPGSQGAPRAPTEKLG 545
           G+ C +      L+ T  +  ++  GP     PRAP +P  P+ PP  +   R P + L 
Sbjct: 810 GRSCSMDSAYGTLSPT-SLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLS 868

Query: 546 GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKAL----------GGATQGTGTL 595
               L      A++       +L A  GT G  +  S++L          G  TQG+   
Sbjct: 869 CPPHLLKSKSEASLL------QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQE 922

Query: 596 SRDA--SREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS-TWPCSQKEPGPPGV 650
           +  +   R   + G   GL   +   A     +  K    +PS   P  Q EP PPGV
Sbjct: 923 AGPSWDCRGAPSPGSGPGLVGCL---AGEPAGSHRKRCGDLPSGASPRVQPEP-PPGV 976


>gi|111154078 pleckstrin homology domain containing family G member 5
            isoform c [Homo sapiens]
          Length = 1062

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 74/298 (24%), Positives = 113/298 (37%), Gaps = 35/298 (11%)

Query: 372  PKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPSE 431
            P S+QP      +E   +      EE+++E E  GT AA+ P          +  H  S+
Sbjct: 751  PGSQQPLQSLEEEEDEQEEEEEE-EEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASD 809

Query: 432  GPLGPSPDDDLCVSESLSGPALGT-PLSICSFRVGAEENLAPA-PGPDLLSQGFLQSSWK 489
            G         +   ++LS P   + P S  S         + A P  +LL  G +     
Sbjct: 810  GSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVD---- 865

Query: 490  GKECLLKLCDTELAITMGIVSWLRRGP----TPRAPPTPGQPAAPPGSQGAPRAPTEKLG 545
            G+ C +      L+ T  +  ++  GP     PRAP +P  P+ PP  +   R P + L 
Sbjct: 866  GRSCSMDSAYGTLSPT-SLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLS 924

Query: 546  GREGLASDAGGATVCSAPSRQELWAHPGTTGLLAGESKAL----------GGATQGTGTL 595
                L      A++       +L A  GT G  +  S++L          G  TQG+   
Sbjct: 925  CPPHLLKSKSEASLL------QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQE 978

Query: 596  SRDA--SREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS-TWPCSQKEPGPPGV 650
            +  +   R   + G   GL   +   A     +  K    +PS   P  Q EP PPGV
Sbjct: 979  AGPSWDCRGAPSPGSGPGLVGCL---AGEPAGSHRKRCGDLPSGASPRVQPEP-PPGV 1032


>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 824

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 67/286 (23%), Positives = 103/286 (36%), Gaps = 49/286 (17%)

Query: 373 KSEQPESVSTSDEGY--YDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPS 430
           +SEQP  + +  + +  ++      EED ++ E               GD   E    P+
Sbjct: 64  RSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEA---PA 120

Query: 431 EGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKG 490
            GPL PSP        S+  P    P ++    +GA+++L    G DL+      +SW+ 
Sbjct: 121 PGPLIPSP--------SVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRP----ASWQ- 167

Query: 491 KECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGL 550
                     E A+       LR  P P     P     P G+Q   R   +  G R   
Sbjct: 168 ----------ETALCSPAPEALRELPGP----LPATDTGPGGAQSPVRPGCDCEGNRPAE 213

Query: 551 ASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSE 610
               GG    ++PS     + PG    L   S    G  + +  LS   S  E+  G   
Sbjct: 214 PPAPGG----TSPS-----SDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARL 264

Query: 611 GLFSS------MESAATSTTDTSGKNKAPVPSTWPCSQ--KEPGPP 648
           G   S      +E ++   + +SG++     S    S    EP PP
Sbjct: 265 GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 310


>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
           isoform 2 [Homo sapiens]
          Length = 797

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 67/286 (23%), Positives = 103/286 (36%), Gaps = 49/286 (17%)

Query: 373 KSEQPESVSTSDEGY--YDSFSPGLEEDKKEAESPGTPAATFPRDSYSGDALYELFHDPS 430
           +SEQP  + +  + +  ++      EED ++ E               GD   E    P+
Sbjct: 37  RSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEA---PA 93

Query: 431 EGPLGPSPDDDLCVSESLSGPALGTPLSICSFRVGAEENLAPAPGPDLLSQGFLQSSWKG 490
            GPL PSP        S+  P    P ++    +GA+++L    G DL+      +SW+ 
Sbjct: 94  PGPLIPSP--------SVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRP----ASWQ- 140

Query: 491 KECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPGSQGAPRAPTEKLGGREGL 550
                     E A+       LR  P P     P     P G+Q   R   +  G R   
Sbjct: 141 ----------ETALCSPAPEALRELPGP----LPATDTGPGGAQSPVRPGCDCEGNRPAE 186

Query: 551 ASDAGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSE 610
               GG    ++PS     + PG    L   S    G  + +  LS   S  E+  G   
Sbjct: 187 PPAPGG----TSPS-----SDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARL 237

Query: 611 GLFSS------MESAATSTTDTSGKNKAPVPSTWPCSQ--KEPGPP 648
           G   S      +E ++   + +SG++     S    S    EP PP
Sbjct: 238 GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 283


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 124/515 (24%), Positives = 156/515 (30%), Gaps = 95/515 (18%)

Query: 187 PGDPSDPGGRRSKAFLPPGEGPGLDGLCQDLLDSELLADASFGL-CRALCEDVA-SLQSF 244
           PGD   PG R    F  P    G DGL      S LL+     L  + +C D        
Sbjct: 518 PGDKGSPGSRGLPGFPGPQGPAGRDGL------SSLLSPGDINLLAKDVCNDCPPGPPGL 571

Query: 245 DSLTGCGEVFADESSVPSLELNEGPESPTQAA--QGLESKVPRGPLQGSVEQLASPAQNE 302
             L G    F  +  VP     EG E     A   GL         QGS  +  +  +  
Sbjct: 572 PGLPG----FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE-- 625

Query: 303 ASDFTRFWDSVNRSVRQQQRALLGPWLSGPQGTDRDQSRLDTAGLAELPLCPCRDPRSGS 362
                     V +   Q    +  P   GP G          AG A  P       + G 
Sbjct: 626 ----------VGQKGDQGHPGV--PGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 673

Query: 363 KASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESPGTPAATFPRD-----SY 417
                 +G P     E     D        PG   +  +A  PG P     R       +
Sbjct: 674 PGPQGPSGLPGIPGEEGKEGRDG------KPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 727

Query: 418 SGDALYELFHDPSEGPLGPSPDDDLCVSESLSGPALGT----PLSICSFRVGAEENLAP- 472
           +GD+        + GP G S    L   E L G    T    P      R    +N +P 
Sbjct: 728 TGDS-------GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 780

Query: 473 APGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRAPPTPGQPAAPPG 532
           +PG    S    Q   KG+             + G+  +L     PR PP        PG
Sbjct: 781 SPGEPGPSGTPGQKGSKGENG-----------SPGLPGFLG----PRGPPGEPGEKGVPG 825

Query: 533 SQGAPRAPTEK----LGGREGLASDAGGATVCSAPSRQELWAHPGTTGL-----LAGESK 583
            +G P  P E       G  G+  D G       P    +  H G TGL     L GE+ 
Sbjct: 826 KEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENG 885

Query: 584 ALG-----GATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTW 638
            +G     G     G      S E   R   E L   +E+                P+  
Sbjct: 886 PVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP------PAYM 939

Query: 639 PCSQKEPGPPGV---------LGCFRGPWRPGHGG 664
             SQ  PGPPG           G    P RPG GG
Sbjct: 940 KSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG 974



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 57/222 (25%), Positives = 66/222 (29%), Gaps = 53/222 (23%)

Query: 521 PPTPGQPAAP--PGSQGAPRAPTEKLG--GREGLASDAGGATVCSAPSRQELWAHPGTTG 576
           P  PG+P     PG  G P+ PT   G  G+EG     G A    AP       H G  G
Sbjct: 358 PGLPGEPGLQGRPGELG-PQGPTGPPGAKGQEGAHGAPGAAGNPGAPG------HVGAPG 410

Query: 577 LLAGESKALGGATQGTGTLSRDASREEETRGHSEGLFSSMESAATSTTDTSGKNKAPVPS 636
                     GA    GT  +D  R E+     EG                         
Sbjct: 411 PSGPPGSV--GAPGLRGTPGKDGERGEKGAAGEEG------------------------- 443

Query: 637 TWPCSQKEPGPPGVLGCFRGPWRPGHGGDTLDAEPMLAGCVARVAALKISSNEQP---PA 693
                   PGP G  G    P  PG  G   D EP L G       L    +      P 
Sbjct: 444 -------SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPG 496

Query: 694 AWPPRQDMGSGLFGQRWARGPDMLEQKQSSSSPSMTTIHGLP 735
           +   R D G G+ G     GP          SP    + G P
Sbjct: 497 SPGSRGDPGIGVAGPPGPSGP-----PGDKGSPGSRGLPGFP 533



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 43/170 (25%), Positives = 54/170 (31%), Gaps = 28/170 (16%)

Query: 521 PPTPGQPAAP--PGSQGAPRAPTEKLGGREGLASDAGGATVCSAP-------SRQELWA- 570
           P  PG P  P   G +G P  P  +  G EG   +AG   +   P       S+ E  A 
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGRE--GTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 623

Query: 571 ----------HPGTTGLLAGESK----ALGGATQGTGTLSRDASREEETRGHSEGLFSSM 616
                     HPG  G +            G     G      S  +E     +G   S 
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQG--PSG 681

Query: 617 ESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLGCFRGPWRPGHGGDT 666
                      G++  P P   P    EPG PG  G    P   GH GD+
Sbjct: 682 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 731


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 70/327 (21%), Positives = 113/327 (34%), Gaps = 61/327 (18%)

Query: 359 RSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESP-GTPAATFPRDSY 417
           R   + +++     +   P S S S E          EE++ EAE+   TP       S 
Sbjct: 63  RKAEEDAALQAKKTRVSDPISTSESSE----------EEEEAEAETAKATPRLASTNSSV 112

Query: 418 SGDALYELFHDPSE---------GPLGPSPDDDLCVSESLSG--------PALGTPLSIC 460
            G  L     + ++         G   P P     V+  LSG        P+  T L   
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172

Query: 461 SFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRA 520
           +   G+      A  P ++S G   SS +         D E+  +  I+         + 
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232

Query: 521 PPTPGQPAAPPGSQGAPRAPT---------------------EKLGGREGLASDAGGAT- 558
            P  G   APPG  GA  + T                     E    +  L + A G T 
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292

Query: 559 ---VCSAPSRQE-----LWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSE 610
                SAP+++        A PG TG    +++A G   + + + S ++  EEE    ++
Sbjct: 293 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA-GKREEDSQSSSEESDSEEEAPAQAK 351

Query: 611 --GLFSSMESAATSTTDTSGKNKAPVP 635
             G    + +A+    ++  K  AP P
Sbjct: 352 PSGKAPQVRAASAPAKESPRKGAAPAP 378


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 76/349 (21%), Positives = 118/349 (33%), Gaps = 71/349 (20%)

Query: 359 RSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESP-GTPAATFPRDSY 417
           R   + +++     +   P S S S E          EE++ EAE+   TP       S 
Sbjct: 63  RKAEEDAALQAKKTRVSDPISTSESSE----------EEEEAEAETAKATPRLASTNSSV 112

Query: 418 SGDALYELFHDPSE---------GPLGPSPDDDLCVSESLSG--------PALGTPLSIC 460
            G  L     + ++         G   P P     V+  LSG        P+  T L   
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172

Query: 461 SFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTE-------LAITMGIVSWLR 513
           +   G+      A  P ++S G   SS +         D E         +    VS  +
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVS-TK 231

Query: 514 RGPTPRAPPTPGQPA---------APPGSQGAPRAPTEKLGGREGLASD----------- 553
             P  +A P PG+           A P ++ A +   E     EG  S+           
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291

Query: 554 ----------AGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREE 603
                     A  A     P +    A PG  G +A ++KA G   + + + S ++S  E
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA-GKPEEDSESSSEESSDSE 350

Query: 604 ETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLG 652
           E    ++ L   +++ A+  T   G   AP   + P     P PPG  G
Sbjct: 351 EETPAAKAL---LQAKASGKTSQVGAASAPAKES-PRKGAAPAPPGKTG 395


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 76/349 (21%), Positives = 118/349 (33%), Gaps = 71/349 (20%)

Query: 359 RSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESP-GTPAATFPRDSY 417
           R   + +++     +   P S S S E          EE++ EAE+   TP       S 
Sbjct: 63  RKAEEDAALQAKKTRVSDPISTSESSE----------EEEEAEAETAKATPRLASTNSSV 112

Query: 418 SGDALYELFHDPSE---------GPLGPSPDDDLCVSESLSG--------PALGTPLSIC 460
            G  L     + ++         G   P P     V+  LSG        P+  T L   
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172

Query: 461 SFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTE-------LAITMGIVSWLR 513
           +   G+      A  P ++S G   SS +         D E         +    VS  +
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVS-TK 231

Query: 514 RGPTPRAPPTPGQPA---------APPGSQGAPRAPTEKLGGREGLASD----------- 553
             P  +A P PG+           A P ++ A +   E     EG  S+           
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291

Query: 554 ----------AGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREE 603
                     A  A     P +    A PG  G +A ++KA G   + + + S ++S  E
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA-GKPEEDSESSSEESSDSE 350

Query: 604 ETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLG 652
           E    ++ L   +++ A+  T   G   AP   + P     P PPG  G
Sbjct: 351 EETPAAKAL---LQAKASGKTSQVGAASAPAKES-PRKGAAPAPPGKTG 395


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 70/327 (21%), Positives = 113/327 (34%), Gaps = 61/327 (18%)

Query: 359 RSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESP-GTPAATFPRDSY 417
           R   + +++     +   P S S S E          EE++ EAE+   TP       S 
Sbjct: 63  RKAEEDAALQAKKTRVSDPISTSESSE----------EEEEAEAETAKATPRLASTNSSV 112

Query: 418 SGDALYELFHDPSE---------GPLGPSPDDDLCVSESLSG--------PALGTPLSIC 460
            G  L     + ++         G   P P     V+  LSG        P+  T L   
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172

Query: 461 SFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTELAITMGIVSWLRRGPTPRA 520
           +   G+      A  P ++S G   SS +         D E+  +  I+         + 
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232

Query: 521 PPTPGQPAAPPGSQGAPRAPT---------------------EKLGGREGLASDAGGAT- 558
            P  G   APPG  GA  + T                     E    +  L + A G T 
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292

Query: 559 ---VCSAPSRQE-----LWAHPGTTGLLAGESKALGGATQGTGTLSRDASREEETRGHSE 610
                SAP+++        A PG TG    +++A G   + + + S ++  EEE    ++
Sbjct: 293 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA-GKREEDSQSSSEESDSEEEAPAQAK 351

Query: 611 --GLFSSMESAATSTTDTSGKNKAPVP 635
             G    + +A+    ++  K  AP P
Sbjct: 352 PSGKAPQVRAASAPAKESPRKGAAPAP 378


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 76/349 (21%), Positives = 118/349 (33%), Gaps = 71/349 (20%)

Query: 359 RSGSKASSIDTGTPKSEQPESVSTSDEGYYDSFSPGLEEDKKEAESP-GTPAATFPRDSY 417
           R   + +++     +   P S S S E          EE++ EAE+   TP       S 
Sbjct: 63  RKAEEDAALQAKKTRVSDPISTSESSE----------EEEEAEAETAKATPRLASTNSSV 112

Query: 418 SGDALYELFHDPSE---------GPLGPSPDDDLCVSESLSG--------PALGTPLSIC 460
            G  L     + ++         G   P P     V+  LSG        P+  T L   
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172

Query: 461 SFRVGAEENLAPAPGPDLLSQGFLQSSWKGKECLLKLCDTE-------LAITMGIVSWLR 513
           +   G+      A  P ++S G   SS +         D E         +    VS  +
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVS-TK 231

Query: 514 RGPTPRAPPTPGQPA---------APPGSQGAPRAPTEKLGGREGLASD----------- 553
             P  +A P PG+           A P ++ A +   E     EG  S+           
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291

Query: 554 ----------AGGATVCSAPSRQELWAHPGTTGLLAGESKALGGATQGTGTLSRDASREE 603
                     A  A     P +    A PG  G +A ++KA G   + + + S ++S  E
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA-GKPEEDSESSSEESSDSE 350

Query: 604 ETRGHSEGLFSSMESAATSTTDTSGKNKAPVPSTWPCSQKEPGPPGVLG 652
           E    ++ L   +++ A+  T   G   AP   + P     P PPG  G
Sbjct: 351 EETPAAKAL---LQAKASGKTSQVGAASAPAKES-PRKGAAPAPPGKTG 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,685,166
Number of Sequences: 37866
Number of extensions: 2567708
Number of successful extensions: 14897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 442
Number of HSP's that attempted gapping in prelim test: 12156
Number of HSP's gapped (non-prelim): 2959
length of query: 861
length of database: 18,247,518
effective HSP length: 111
effective length of query: 750
effective length of database: 14,044,392
effective search space: 10533294000
effective search space used: 10533294000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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