Guide to the Human Genome
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Search of human proteins with 157426839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426839 PRAME family member 17 [Homo sapiens]
         (474 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426839 PRAME family member 17 [Homo sapiens]                    976   0.0  
gi|113865933 PRAME family member 16 [Homo sapiens]                    974   0.0  
gi|194018546 PRAME family member 10 [Homo sapiens]                    844   0.0  
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ...   739   0.0  
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ...   739   0.0  
gi|154800493 PRAME family member 22 [Homo sapiens]                    571   e-163
gi|153791443 PRAME family member 18 [Homo sapiens]                    565   e-161
gi|194306638 PRAME family member 3 [Homo sapiens]                     565   e-161
gi|194306635 PRAME family member 19 [Homo sapiens]                    562   e-160
gi|12738831 PRAME family member 1 [Homo sapiens]                      553   e-157
gi|66954681 PRAME family member 13 [Homo sapiens]                     544   e-155
gi|12738834 PRAME family member 2 [Homo sapiens]                      531   e-151
gi|153792140 PRAME family member 14 [Homo sapiens]                    516   e-146
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    493   e-139
gi|124249372 PRAME family member 12 [Homo sapiens]                    447   e-125
gi|153792112 PRAME family member 20 [Homo sapiens]                    444   e-125
gi|153945800 PRAME family member 21 [Homo sapiens]                    444   e-125
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   440   e-123
gi|59676587 PRAME family member 8 [Homo sapiens]                      440   e-123
gi|59676593 PRAME family member 7 [Homo sapiens]                      437   e-123
gi|148356236 PRAME family member 15 [Homo sapiens]                    412   e-115
gi|61102721 PRAME family member 9 [Homo sapiens]                      412   e-115
gi|61696142 PRAME family member 5 [Homo sapiens]                      408   e-114
gi|58219004 PRAME family member 6 [Homo sapiens]                      408   e-114
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         404   e-113
gi|59958373 PRAME family member 4 [Homo sapiens]                      404   e-113
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         403   e-112
gi|226437621 PRAME family member 11 [Homo sapiens]                    360   1e-99
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   353   2e-97
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   353   2e-97

>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  976 bits (2522), Expect = 0.0
 Identities = 474/474 (100%), Positives = 474/474 (100%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
           FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
           CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
           NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  974 bits (2517), Expect = 0.0
 Identities = 473/474 (99%), Positives = 473/474 (99%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSCSPEAM KRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
           FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
           CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
           NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  844 bits (2180), Expect = 0.0
 Identities = 416/474 (87%), Positives = 436/474 (91%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FL LPLGSLMKT HLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61  FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PR GEHQPLKVFIDLC KESTLDECLSYL  WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LFLA
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
           FGY+ ELYVS Q   +PDLD PFLCLYYPQMLYI+KISNIKEHLEHLLR LKNPLG FIF
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
             AYL D+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HTGGLSKLGLELYPAPLE LD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
            +GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS 474


>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  739 bits (1908), Expect = 0.0
 Identities = 376/474 (79%), Positives = 392/474 (82%), Gaps = 48/474 (10%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PR GE QPLKVFIDLC KESTLDECLSYL  WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
                                                           R LKNPLG FIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
             AYL D+DMECLSQYPSLSQLKEL LIHILMWTTNLEPLG LLEKVAATL+ L LKDC+
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
            +GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426


>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  739 bits (1907), Expect = 0.0
 Identities = 376/474 (79%), Positives = 393/474 (82%), Gaps = 48/474 (10%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+PSRLLELAGQSLLRNQFLTIF LDELPREVFPLMFMEA SMR FEALKLMVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMKTPHLETLQAVL+GLDTL+AQK+RPRRWKLQVLDLRDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PR GE QPLKVFIDLC KESTLDECLSYL  WIHYRRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+KVQNYSMPTSSFRNLL+R+YPDSIQELE+ +KCSLNKTGKFAPYLSQMSNLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
                                                           R LKNPLG FIF
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
             AYLAD+DMECLSQYPSLSQLKEL LIHILMWTT+LEPLG LLEKVAATL+ L LKDC+
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           IQD QLRVLLPALS CSQLTTF F GNETS NALKDLL HT GLSKLGLELYPAPLE LD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLCS 474
            +GHVNWEIL PIRAELM TLREVRQPKRIFFGP+PCP+CGSWPSEKVDFHLCS
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS 426


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  571 bits (1472), Expect = e-163
 Identities = 294/473 (62%), Positives = 354/473 (74%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE  +DE LS+   W+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      +F+ YLSQM NLRKLF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
            G    L    Q+Q V +     L L Y QMLY+R++   + HL+ L+RCL++PL T   
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            + +L   D++CL +YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           +RG V  E+L P++AELM  LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  565 bits (1457), Expect = e-161
 Identities = 292/473 (61%), Positives = 350/473 (73%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE ++DE LS+   W+ +RR  VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      + + YLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
            G         Q Q V +    FL L Y QMLY+R+I   + +L+ L+RCLK+PL T   
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            +  L ++D++CL  YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I DS+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           NRG V  E+L P++AELM  LREVR+P RIFFGP+ CP CG  P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  565 bits (1456), Expect = e-161
 Identities = 293/473 (61%), Positives = 352/473 (74%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE  +DE LS+   W+ +RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      +F  YLSQM NLRKLF++
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
            G    L    Q+Q V +     L L Y QMLY+R++   + HL+ L+RCL++PL T   
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            + +L   D++CL +YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           +RG V  E+L P++AELM  LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  562 bits (1448), Expect = e-160
 Identities = 291/473 (61%), Positives = 349/473 (73%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE ++DE LS+   W+ +RR  VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      + + YLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
            G         Q Q V +    FL L Y QMLY+R+I   + +L+ L+RCLK+PL T   
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            +  L ++D++CL  YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I  S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           NRG V  E+L P++AELM  LREVR+P RIFFGP+ CP CG  P+E+++F+ C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  553 bits (1426), Expect = e-157
 Identities = 289/477 (60%), Positives = 345/477 (72%), Gaps = 8/477 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+Q+P RLLELAGQSLLR+Q L+I  ++ELPR ++  +FMEA S RHF+ L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKT HLETL+A+L+GL  LL QK RPRRWKLQVLDLRDVD NFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSC PE  SKRQT ED PR GEHQPLKVFID+C KE   DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+K+ NY  P    R  LK +Y +SIQELEI+         K   YL +M NLRKL  +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
               +  D+EL    Q + V      FL L + Q+L I+ I+    HLE L+RCL+NPL 
Sbjct: 241 RCHHYTSDNEL----QGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296

Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
                + YL ++DM+CLSQYPSL  LK L+L ++L++  +LEPLGALLEK+AA+L+ L L
Sbjct: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLIL 356

Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
           + CQI  SQL  +LPALSRCSQLTTFYF  N  S +ALKDLL HT GLSKL LE YPAP 
Sbjct: 357 EGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416

Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           E L++   VNWEI  P+RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  544 bits (1402), Expect = e-155
 Identities = 285/477 (59%), Positives = 342/477 (71%), Gaps = 8/477 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+Q+P RLLELAGQSLLR+Q L+I  ++ELPR ++  +FMEA   RHF+ L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKT HLETL+A+L+GL  LL QK RPRRWKLQVLDLRDVD NFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSC PE MSKRQT ED PR GEHQPLKVFID+C KE   DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+K+ NY  P    R  LK +Y +SIQ+LEI+         K   YL +M NLRKL  +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 FGY----DDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
             +    D+EL    + + V      FL L + Q+L I+ I+    HLE L+RCL+NPL 
Sbjct: 241 RCHHSMSDNEL----EGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296

Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
                + YL ++DM+CLSQYPSL  LK L+L ++L++  +LEPLGALLEK+AA+LE L L
Sbjct: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLIL 356

Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
           + CQI  SQL  +LP LS CSQLTTFYF  N  S  ALKDLL HT GLSKL LE YPAP 
Sbjct: 357 EGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPE 416

Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           E L++   V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|12738834 PRAME family member 2 [Homo sapiens]
          Length = 474

 Score =  531 bits (1368), Expect = e-151
 Identities = 281/477 (58%), Positives = 337/477 (70%), Gaps = 8/477 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+Q+P RLLELAGQSLLR+Q L+I  ++ELPR ++  +F EA S RHF+ L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPL SLMKT HLE L+A+L+GL  LL QK RPRRWKLQVLDLRDVD NFW  W GA 
Sbjct: 61  FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSC PEAMSKRQT ED PRTGEHQPLKVFID+C KE   DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+K+ NY  P    R  LK +Y +SI ELEI   C  +   K   YL +M  L KL  +
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240

Query: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
               +  D+EL    +   V      FL L + Q+L I+ I+    HLE L+RCL+NPL 
Sbjct: 241 RCHHYTSDNEL----EGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296

Query: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
                   L ++D++CLSQ+PSL  LK L+L ++L++  +LEPLGALLEK+AA+LE L L
Sbjct: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356

Query: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
           + CQI  SQL  +LP LS CSQLTTFYF  N  S +ALKDLL HT GLSKL LE YPAP 
Sbjct: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416

Query: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           E L++   VNWEI  P+RAELMCTLRE RQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|153792140 PRAME family member 14 [Homo sapiens]
          Length = 426

 Score =  516 bits (1329), Expect = e-146
 Identities = 271/473 (57%), Positives = 319/473 (67%), Gaps = 48/473 (10%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+Q+P RLLELAGQSLLR+Q L+I  ++ELPR ++  +FMEA   RHF+ L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKT HLETL+A+L+GL  LL QK RPRRWKLQVLDLRDVD NFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALSC PE MSKRQT ED PR GEHQPLKVFID+C KE   DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC+K+ NY  P    R  LK +Y +SIQ+LEI+         K   YL +M NLRKL  +
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
                                                           RCL+NPL     
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            + YL ++DM+CLSQYPSL  LK L+L ++L++  +LEPLGALLEK+AA+LE L L+ CQ
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I  SQL  +LP LS CSQLTTFYF  N  S  ALKDLLCHT GLSKL LE YPAP E L+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
           +   V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  493 bits (1268), Expect = e-139
 Identities = 270/462 (58%), Positives = 318/462 (68%), Gaps = 1/462 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE  +DE LS+   W+ +RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      +F+PYLSQM NLRKLF++
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240

Query: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
            G    L    Q+Q  P     FL L+  Q LY+  +S ++ HL+ LL CLK  L     
Sbjct: 241 DGCRYLLSSDSQEQIAP-FTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299

Query: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
            +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L DC 
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359

Query: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
           I DSQ+  +LPALSRC +L TF F GN  S   L++LL HT  L  L LELYPAP E   
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419

Query: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
             G + W     IRAELM  +R++R PKRI FG   CP CG+
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  447 bits (1149), Expect = e-125
 Identities = 250/467 (53%), Positives = 313/467 (67%), Gaps = 13/467 (2%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MSLQ+P RLLELA QSLLR++ L I  L+ELPRE+FP +FMEA + R  E L  MVQAWP
Sbjct: 1   MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F  LPLGSLMK+ +LE  +AVL+GLD LLAQK+RPRRWKLQVLDLR+VD NFW IWSGA 
Sbjct: 61  FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           ALS  PEA+SKR+T  + PR G  QPL V +DLC K   LDECL++   W   R+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC ++Q + +       +L  V  D IQE+E+     L+   +FAPYL QM NLRKL L 
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238

Query: 241 FGYDDELYVSG------QQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNP 294
                 ++VS       ++QFV      FL L Y Q LY+  +S ++ HL+ LLRCL+ P
Sbjct: 239 -----NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAP 293

Query: 295 LGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEIL 354
           L T +     L++ D++ LS  PS+ QLKEL L  I +   + EPL  LLE+  ATL+ L
Sbjct: 294 LETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTL 353

Query: 355 TLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPA 414
            L+DC I DSQL  +LPALSRCSQL+TF F GN  S  AL++LL HT GLSKL LELYPA
Sbjct: 354 DLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPA 413

Query: 415 PLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
           PLE  D +G + W   + + AELM TLR++RQPK I F  +PCP CG
Sbjct: 414 PLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCG 460


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  444 bits (1142), Expect = e-125
 Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR++ L I  L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMK P  ET QAVL GLD LL  ++R RRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C P AM  R+ V+D PR    QPL VFIDLC K  TLDE  + L  W+  R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   M   + RN+LK V  D IQE+E+    +L    +F PYL QM NLRKL L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
               D  Y+S +Q  +FV      FL L   Q LY+  +S ++ HL+ +L CLK  L   
Sbjct: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LS+YPS+ QLK L L    +   +L PL  LLEKVAATLE L L D
Sbjct: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +LTTF FRGN  ST  L++LLCHT  L+ L LELYPAP E 
Sbjct: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
            D RG V     A + AELM  +R +R+P+RI F    CP CG+
Sbjct: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  444 bits (1142), Expect = e-125
 Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR++ L I  L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           FLRLPLGSLMK P  ET QAVL GLD LL  ++R RRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C P AM  R+ V+D PR    QPL VFIDLC K  TLDE  + L  W+  R GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   M   + RN+LK V  D IQE+E+    +L    +F PYL QM NLRKL L+
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
               D  Y+S +Q  +FV      FL L   Q LY+  +S ++ HL+ +L CLK  L   
Sbjct: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LS+YPS+ QLK L L    +   +L PL  LLEKVAATLE L L D
Sbjct: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +LTTF FRGN  ST  L++LLCHT  L+ L LELYPAP E 
Sbjct: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
            D RG V     A + AELM  +R +R+P+RI F    CP CG+
Sbjct: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  440 bits (1132), Expect = e-123
 Identities = 244/463 (52%), Positives = 311/463 (67%), Gaps = 5/463 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELA Q LLR+Q L I  ++ELPRE+FP +FMEA S R  E LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A    PEA+S++QT ++ P TG  QP  VFIDLC K  TLDECL++L  W   R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC ++Q + MP  S   +L  V  D IQE+E+     L+   KFAPYL QM NLRKL L 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237

Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
           F       +    + QF+      FL L Y Q L +  +S ++ HL+ LLRCL+  L   
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
           +     L++ D++ LS  PS+ QLKEL L  + +   + EPL  LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQL  +LP LSRCSQL+TF F GN  S  AL++LL HT GLSKL LELYPAPLE 
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
            D +G + W   A + AELM TLR++RQPK I F  +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  440 bits (1132), Expect = e-123
 Identities = 244/463 (52%), Positives = 311/463 (67%), Gaps = 5/463 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELA Q LLR+Q L I  ++ELPRE+FP +FMEA S R  E LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A    PEA+S++QT ++ P TG  QP  VFIDLC K  TLDECL++L  W   R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC ++Q + MP  S   +L  V  D IQE+E+     L+   KFAPYL QM NLRKL L 
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237

Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
           F       +    + QF+      FL L Y Q L +  +S ++ HL+ LLRCL+  L   
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
           +     L++ D++ LS  PS+ QLKEL L  + +   + EPL  LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQL  +LP LSRCSQL+TF F GN  S  AL++LL HT GLSKL LELYPAPLE 
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
            D +G + W   A + AELM TLR++RQPK I F  +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCG 460


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  437 bits (1125), Expect = e-123
 Identities = 243/463 (52%), Positives = 310/463 (66%), Gaps = 5/463 (1%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELA Q LLR+Q L I  ++ELPRE+FP +FMEA S R  E LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPLGSLMK+PHLE+L++VL+G+D LL Q++RPR+ KLQVLDLR+VD NF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A    PEA+S++QT ++ P TG  QP  VFIDLC K  TLDECL++L  W   R+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC ++Q + MP  S   +L  V  D IQE+E+     L+   KFAPYL QM NLRKL L 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVL- 237

Query: 241 FGYDDELYV--SGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
           F       +    + QF+      FL L Y Q L +  +S ++ HL+ LLRCL+  L   
Sbjct: 238 FNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMV 297

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
           +     L++ D++ LS  PS+ QLKEL L  + +   + EPL  LLE+V ATL+ L L+D
Sbjct: 298 VMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLED 357

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQL  +LP LSRCSQL+TF F GN  S  AL++LL HT GLSKL LELYPAPLE 
Sbjct: 358 CGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLES 417

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
            D +G + W   A + AELM T R++RQPK I F  +PCP CG
Sbjct: 418 YDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCG 460


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  412 bits (1060), Expect = e-115
 Identities = 235/464 (50%), Positives = 292/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   ++ V+D PR    QPL VF++L  K  TLDE L+YL  W+  R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L +ELYPAP E 
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
               G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  412 bits (1060), Expect = e-115
 Identities = 235/464 (50%), Positives = 292/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   ++ V+D PR    QPL VF++L  K  TLDE L+YL  W+  R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L +ELYPAP E 
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
               G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  408 bits (1049), Expect = e-114
 Identities = 234/464 (50%), Positives = 291/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q + PRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   ++ V+D PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q L +  +S ++ HL+ LL CLK  L   
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN  S   L++LL HT  L  L +ELYPAP E 
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
            D  G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  408 bits (1048), Expect = e-114
 Identities = 234/464 (50%), Positives = 290/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q + PRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   +  V+D PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q L +  +S ++ HL+ LL CLK  L   
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN  S   L++LL HT  L  L +ELYPAP E 
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
            D  G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  404 bits (1039), Expect = e-113
 Identities = 234/463 (50%), Positives = 286/463 (61%), Gaps = 3/463 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS++ P RLLEL G+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 38  MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 98  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   +  V+D PR  E QPL VF++L  K  TLDE L+ L  W+  RR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  + NL+KL L+
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L LELYPAP E 
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
               G + W   A IRAELM  +R +R PKRI F    CP  G
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  404 bits (1038), Expect = e-113
 Identities = 233/464 (50%), Positives = 289/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+ +P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQ+WP
Sbjct: 3   MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL   +RPRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   ++ VED PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q LY+  +S ++ HL+ LL CLK  L   
Sbjct: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALSRC +L TF F GN      L++LL HT  L  L +ELYPAP E 
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
               G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  403 bits (1036), Expect = e-112
 Identities = 232/464 (50%), Positives = 289/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
           F RLPL  L+K P LE  QAVL GLD LL Q + PRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
           A  C   A   ++ V+D PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
              D   YVS +Q  + V      FL L   Q L +  +S ++ HL+ LL CLK  L   
Sbjct: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299

Query: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359

Query: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
           C I DSQ+  +LPALS C +L TF F GN  S   L++LL HT  L  L +ELYPAP E 
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419

Query: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
            D  G + W     IRAELM  +R++R PKRI F    CP CG+
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  360 bits (925), Expect = 1e-99
 Identities = 211/423 (49%), Positives = 255/423 (60%), Gaps = 3/423 (0%)

Query: 41  MEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKL 100
           MEA S R  EALKLMVQAWPF RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 101 QVLDLRDVDGNFWTIWSGARALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTL 160
           QVLDL+DV  NFW +WS A A  C   A   +  V+D PR  E QPL VF++L  K  TL
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 161 DECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNK 220
           DE L+ L  W+  RR L+HLCC K++   MP  + R++LK V  D IQE+E+  K  L  
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180

Query: 221 TGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKIS 278
             +F PYL  + NL+KL L+   D   YVS +Q  + V      FL L   Q LY+  +S
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239

Query: 279 NIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLE 338
            ++ HL+ LL CLK  L      +  L + D++ LSQ PS+SQLK L L  I +   +L 
Sbjct: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299

Query: 339 PLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLL 398
           PL  LLEKVAATLE L L DC I DSQ+  +LPALSRC +L TF F GN      L++LL
Sbjct: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359

Query: 399 CHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCP 458
            HT  L  L LELYPAP E     G + W   A IRAELM  +R +R PKRI F    CP
Sbjct: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419

Query: 459 SCG 461
             G
Sbjct: 420 DHG 422


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  353 bits (905), Expect = 2e-97
 Identities = 213/471 (45%), Positives = 286/471 (60%), Gaps = 15/471 (3%)

Query: 5   SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64
           SP RL+ELAGQSLL+++ L I  L+ LPRE+FP +FM A   RH + LK MVQAWPF  L
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 65  PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121
           PLG LMK  HL  ET +AVL GLD LLAQ++RPRRWKLQVLDLR +   +FWT+WSG RA
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 122 LSCS---PEA---MSKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173
              S   PEA   M+K++ V+      E    P++V +DL  KE   DE  SYL   +  
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233
           ++ ++ LCC K++ ++MP    + +LK V  DSI++LE+     L    KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291
           LR+L L+  +    Y+S +  +Q++      FL L   Q LY+  +  ++  L+ LLR +
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320

Query: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351
            NPL T    +  L++ D+  LSQ PS+SQL  L L  +++   + EPL ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380

Query: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411
           + L   +C I D QL  LLP+LS CSQLTT  F GN  S +AL+ LL H  GLS L   L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440

Query: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
           YP PLE   D  G ++ E LA + A L   L E+ +P  ++    PCP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  353 bits (905), Expect = 2e-97
 Identities = 213/471 (45%), Positives = 286/471 (60%), Gaps = 15/471 (3%)

Query: 5   SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64
           SP RL+ELAGQSLL+++ L I  L+ LPRE+FP +FM A   RH + LK MVQAWPF  L
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 65  PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121
           PLG LMK  HL  ET +AVL GLD LLAQ++RPRRWKLQVLDLR +   +FWT+WSG RA
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 122 LSCS---PEA---MSKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173
              S   PEA   M+K++ V+      E    P++V +DL  KE   DE  SYL   +  
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233
           ++ ++ LCC K++ ++MP    + +LK V  DSI++LE+     L    KF+PYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291
           LR+L L+  +    Y+S +  +Q++      FL L   Q LY+  +  ++  L+ LLR +
Sbjct: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320

Query: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351
            NPL T    +  L++ D+  LSQ PS+SQL  L L  +++   + EPL ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380

Query: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411
           + L   +C I D QL  LLP+LS CSQLTT  F GN  S +AL+ LL H  GLS L   L
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440

Query: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
           YP PLE   D  G ++ E LA + A L   L E+ +P  ++    PCP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,575,680
Number of Sequences: 37866
Number of extensions: 845175
Number of successful extensions: 2479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2355
Number of HSP's gapped (non-prelim): 51
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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