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Search of human proteins with 157389018
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157389018 gamma-aminobutyric acid A receptor, alpha 6
precursor [Homo sapiens]
(453 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 909 0.0
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 577 e-165
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 517 e-147
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 509 e-144
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 503 e-142
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 503 e-142
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 499 e-141
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 499 e-141
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 394 e-110
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 388 e-108
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 384 e-106
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 371 e-103
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 367 e-101
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 318 8e-87
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 280 2e-75
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 278 6e-75
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 277 2e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 277 2e-74
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 276 2e-74
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 276 2e-74
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 272 4e-73
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 263 3e-70
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 261 9e-70
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 254 1e-67
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 253 2e-67
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 909 bits (2350), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 1 MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT 60
MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
Sbjct: 1 MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT 60
Query: 61 DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN 120
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN
Sbjct: 61 DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN 120
Query: 121 GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP 180
GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
Sbjct: 121 GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP 180
Query: 181 KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM 240
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
Sbjct: 181 KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM 240
Query: 241 GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA 300
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
Sbjct: 241 GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA 300
Query: 301 TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI 360
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI
Sbjct: 301 TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI 360
Query: 361 VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY 420
VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY
Sbjct: 361 VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY 420
Query: 421 SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE 453
SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
Sbjct: 421 SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE 453
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 577 bits (1488), Expect = e-165
Identities = 286/374 (76%), Positives = 323/374 (86%), Gaps = 2/374 (0%)
Query: 5 LPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYV 64
L +LC+ + L + G+ + E +EN +RILD+LL+GYDNRLRPGFGG VTEVKTDIYV
Sbjct: 21 LRFLCLAVCLNESPGQNQKEEKLCTENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYV 80
Query: 65 TSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKS 124
TSFGPVSDVEMEYTMDVFFRQTW D+RLK+ GP EIL LNN+MV+K+WTPDTFFRNGKKS
Sbjct: 81 TSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKS 140
Query: 125 IAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
++HNMT PNKLFRIM+NGTILYTMRLTI+A+CPMRLV+FPMDGHACPLKFGSYAYPKSE+
Sbjct: 141 VSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
Query: 185 IYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFM 244
IYTW KGP SVEVP+ESSSL+QYDLIGQTVSSETIKS TGEY++MTVYFHL+RKMGYFM
Sbjct: 201 IYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFM 260
Query: 245 IQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMD 304
IQ Y PCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMD
Sbjct: 261 IQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMD 320
Query: 305 WFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVL-H 363
WFIAVCFAFVFSALIEFAAVNYFTN+Q +KAKRK P V + E L +
Sbjct: 321 WFIAVCFAFVFSALIEFAAVNYFTNIQMEKAKRKTS-KPPQEVPAAPVQREKHPEAPLQN 379
Query: 364 PDSKYHLKKRITSL 377
++ +++KR +L
Sbjct: 380 TNANLNMRKRTNAL 393
Score = 77.4 bits (189), Expect = 2e-14
Identities = 43/87 (49%), Positives = 54/87 (62%), Gaps = 5/87 (5%)
Query: 371 KKRITSLSLPIVSSSEANKVLTRAPILQST---PVTPPPLSP--AFGGTSKIDQYSRILF 425
K + S S V S ++ T + +T TPPP +P + GTSKID+Y+RILF
Sbjct: 467 KASVGSASTRHVFGSRLQRIKTTVNTIGATGKLSATPPPSAPPPSGSGTSKIDKYARILF 526
Query: 426 PVAFAGFNLVYWVVYLSKDTMEVSSSV 452
PV F FN+VYWVVYLSKDTME S S+
Sbjct: 527 PVTFGAFNMVYWVVYLSKDTMEKSESL 553
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 517 bits (1331), Expect = e-147
Identities = 264/428 (61%), Positives = 321/428 (75%), Gaps = 27/428 (6%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G AVTEVKTDIYVTSFGPVSD +MEYT+DVFFRQTW DERL
Sbjct: 68 TRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +IL LNNL+ SKIWTPDTFF NGKKS+AHNMTTPNKL R++ NGT+LYTMRLTI
Sbjct: 128 KFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTI 187
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
+A+CPM L +FPMD HACPLKFGSYAY +E++Y+W G SVEV ++ S L QYDL+G
Sbjct: 188 HAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLG 247
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
V +E I+S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 248 HVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 307
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNL-- 330
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 308 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSW 367
Query: 331 --------QTQKAKRKAQFAAP-----PTVTISKATEPLEAEIVLHPDSKYHLKKRITSL 377
+ + K+K AAP T I T P+ L D+++ I+
Sbjct: 368 AWEGKKVPEALEMKKKTP-AAPAKKTSTTFNIVGTTYPIN----LAKDTEF---STISKG 419
Query: 378 SLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYW 437
+ P SS+ +A +Q +P + + SK+D+ SRI+FPV FA FNLVYW
Sbjct: 420 AAPSASSTPTIIASPKATYVQDSPTE----TKTYNSVSKVDKISRIIFPVLFAIFNLVYW 475
Query: 438 VVYLSKDT 445
Y+++++
Sbjct: 476 ATYVNRES 483
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 509 bits (1310), Expect = e-144
Identities = 255/416 (61%), Positives = 305/416 (73%), Gaps = 17/416 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G +T+V+TDIYVTSFGPVSD EMEYT+DVFFRQ+W DERL
Sbjct: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
+F GP + L LNNL+ SKIWTPDTFF NGKKSIAHNMTTPNKL R+ +GT+LYTMRLTI
Sbjct: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
+A+CPM+L +FPMD HACPLKFGSYAYP SE++Y W G SV V E+ S L QY L+G
Sbjct: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMG 229
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV +E I ++TGEY IMT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 230 QTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 289
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN--- 329
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 290 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 349
Query: 330 -LQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEAN 388
+KA A+ V ++K+T + HP ++P +
Sbjct: 350 AWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPP------------NIPKEQTPAGT 397
Query: 389 KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
T + S T + SKID+ SRI+FPV F FNLVYW YL+++
Sbjct: 398 SNTTSVSVKPSEEKTSES-KKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNRE 452
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 503 bits (1295), Expect = e-142
Identities = 258/418 (61%), Positives = 307/418 (73%), Gaps = 20/418 (4%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G VTEVKTDI+VTSFGPVSD +MEYT+DVFFRQ+W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP +L LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI ++GT+LYTMRLT+
Sbjct: 103 KFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD HACPLKFGSYAY ++E++Y W + P SV V E+ S L QYDL+G
Sbjct: 163 RAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
QTV S ++S+TGEYV+MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQT 332
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT---- 338
Query: 333 QKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLS-LPIVSSSEAN--- 388
K +A K+ P + + V P K + T+ S P ++ +
Sbjct: 339 -----KRGYAWD-----GKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLAT 388
Query: 389 --KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKD 444
K T P PP F SKID+ SRI FP+ F FNLVYW YL+++
Sbjct: 389 IAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNRE 446
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 499 bits (1285), Expect = e-141
Identities = 256/424 (60%), Positives = 300/424 (70%), Gaps = 34/424 (8%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G ++TEV T+IYVTSFGPVSD +MEYT+DVFFRQ W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP IL LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI +GT+LYTMRLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD H+CPLKFGSYAY SE+ Y W SV+V + S L QYDL+G
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Q++ ETIKS+TGEY +MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT---- 328
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 342
Query: 329 -----NLQTQKAKRKAQFAAPP---TVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLP 380
++ K K KA V ++ L + VL SK S + P
Sbjct: 343 AWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISK--------SATTP 394
Query: 381 IVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
+ NK P F SKID+ SRI+FPV F FNLVYW Y
Sbjct: 395 EPNKKPENK--------------PAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
Query: 441 LSKD 444
L+++
Sbjct: 441 LNRE 444
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 499 bits (1285), Expect = e-141
Identities = 256/424 (60%), Positives = 300/424 (70%), Gaps = 34/424 (8%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
+RILD LL+GYDNRLRPG G ++TEV T+IYVTSFGPVSD +MEYT+DVFFRQ W DERL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
KF GP IL LNNLM SKIWTPDTFF NGKKS+AHNMT PNKL RI +GT+LYTMRLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIG 212
A+CPM L +FPMD H+CPLKFGSYAY SE+ Y W SV+V + S L QYDL+G
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLG 222
Query: 213 QTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPAR 272
Q++ ETIKS+TGEY +MT +FHL+RK+GYF+IQ Y PCIMTVILSQVSFW+N+ESVPAR
Sbjct: 223 QSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 282
Query: 273 TVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT---- 328
TVFG+TTVLTMTTLSISAR+SLPKV+YATAMDWFIAVC+AFVFSALIEFA VNYFT
Sbjct: 283 TVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGW 342
Query: 329 -----NLQTQKAKRKAQFAAPP---TVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLP 380
++ K K KA V ++ L + VL SK S + P
Sbjct: 343 AWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISK--------SATTP 394
Query: 381 IVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
+ NK P F SKID+ SRI+FPV F FNLVYW Y
Sbjct: 395 EPNKKPENK--------------PAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
Query: 441 LSKD 444
L+++
Sbjct: 441 LNRE 444
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 394 bits (1012), Expect = e-110
Identities = 206/413 (49%), Positives = 274/413 (66%), Gaps = 14/413 (3%)
Query: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
+V+ IL+NLLEGYDN+LRP G T + TD+YV S GPV+ + MEYT+D+FF QTW D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDR 124
Query: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
RLKF ++L LN+ MV KIW PDTFFRN KK+ AH +TTPN++ RI +G +LYT+RL
Sbjct: 125 RLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 184
Query: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
TI+A+C ++L NFPMD H+CPL+F SY YP+ EI+Y WK+ SVEV + S L Q+
Sbjct: 185 TIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFS 241
Query: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
+G ++E +K+ +G+YV+M+VYF L R+MGYF IQ Y PC + V+LS VSFWINK++V
Sbjct: 242 FVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAV 301
Query: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-T 328
PART GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVFSAL+E+ ++YF +
Sbjct: 302 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVS 361
Query: 329 NLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEAN 388
N + K K K + PT+ I P A I + ++ HL++R + +
Sbjct: 362 NRKPSKDKDKKKKNPAPTIDI----RPRSATIQM--NNATHLQERDEEYGYECLDGKDCA 415
Query: 389 KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYL 441
++ + +K+D Y+RI FP AF FNLVYWV YL
Sbjct: 416 SFFCCFEDCRTGAWRHGRIHIRI---AKMDSYARIFFPTAFCLFNLVYWVSYL 465
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 388 bits (996), Expect = e-108
Identities = 208/422 (49%), Positives = 276/422 (65%), Gaps = 24/422 (5%)
Query: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
+V+ IL+NLLEGYDN+LRP G T + TD+YV S GPV+ + MEYT+D+FF QTW D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDR 124
Query: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
RLKF ++L LN+ MV KIW PDTFFRN KK+ AH +TTPN++ RI +G +LYT+RL
Sbjct: 125 RLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 184
Query: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
TI+A+C ++L NFPMD H+CPL+F SY YP+ EI+Y WK+ SVEV + S L Q+
Sbjct: 185 TIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFS 241
Query: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
+G ++E +K+ +G+YV+M+VYF L R+MGYF IQ Y PC + V+LS VSFWINK++V
Sbjct: 242 FVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAV 301
Query: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-T 328
PART GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVFSAL+E+ ++YF +
Sbjct: 302 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVS 361
Query: 329 NLQTQKAKRKAQ---------FAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL 379
N + K K K + F A PT+ I P A I + ++ HL++R
Sbjct: 362 NRKPSKDKDKKKKNPLLRMFSFKA-PTIDI----RPRSATIQM--NNATHLQERDEEYGY 414
Query: 380 PIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVV 439
+ + ++ + +K+D Y+RI FP AF FNLVYWV
Sbjct: 415 ECLDGKDCASFFCCFEDCRTGAWRHGRIHIRI---AKMDSYARIFFPTAFCLFNLVYWVS 471
Query: 440 YL 441
YL
Sbjct: 472 YL 473
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 384 bits (985), Expect = e-106
Identities = 206/417 (49%), Positives = 267/417 (64%), Gaps = 22/417 (5%)
Query: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
++++IL++LL+GYDN+LRP G T ++TD+YV S GPV + MEYT+D+ F QTW D
Sbjct: 63 DITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDS 122
Query: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
RLKF ++L LN+ MV KIW PDTFFRN +KS AH +TTPN+L RI +G +LYT+RL
Sbjct: 123 RLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRL 182
Query: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
TINA+C ++L NFPMD H+CPL+F SY YPK+EI Y WKK SVEV + L Q+
Sbjct: 183 TINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKP---SVEVADPKYWRLYQFA 239
Query: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
+G S+E + +G+YVIMT++F L R+MGYF IQ Y PCI+TV+LS VSFWINK++V
Sbjct: 240 FVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAV 299
Query: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN 329
PART GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVF+AL+E+ ++YFT+
Sbjct: 300 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTS 359
Query: 330 LQ-----TQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSS 384
Q T+ K K + + P + P+ V D + +
Sbjct: 360 NQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCF 419
Query: 385 SEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYL 441
+ R + +KID YSRI FP AFA FNLVYWV YL
Sbjct: 420 EDCRTGSWREGRIHIR-------------IAKIDSYSRIFFPTAFALFNLVYWVGYL 463
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 371 bits (953), Expect = e-103
Identities = 207/447 (46%), Positives = 267/447 (59%), Gaps = 63/447 (14%)
Query: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
+V+ IL+ LL YD +LRP G T + DIYV S GPVS + MEY +D+FF QTWTD
Sbjct: 46 DVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDS 105
Query: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
RL+F +IL+LN+ MV IW PDT FRN K + AH +TTPN+L RI +G ILYT+RL
Sbjct: 106 RLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRL 165
Query: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
TINA+C ++L NFPMD H+CPL F SY YPK E+IY W+K SVE ++ S L Q+D
Sbjct: 166 TINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKN---SVEAADQKSWRLYQFD 222
Query: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
+G ++E + ++ G+YV+MT+YF L R+MGYF IQ Y PCI+TV+LS VSFWI K++
Sbjct: 223 FMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDAT 282
Query: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN 329
PART GITTVLTMTTLS AR SLP+VSY TAMD F+ VCF FVF+AL+E+A +NY+++
Sbjct: 283 PARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSS 342
Query: 330 LQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANK 389
+ PT T K T +LHPDS + +RI SL P S +
Sbjct: 343 CR------------KPTTT-KKTTS------LLHPDSSRWIPERI-SLQAP----SNYSL 378
Query: 390 VLTRAPILQSTPVTPPPLSPAFGGTS---------------------------------- 415
+ R P + F T
Sbjct: 379 LDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDI 438
Query: 416 -KIDQYSRILFPVAFAGFNLVYWVVYL 441
++D YSR+ FP +F FNLVYWV YL
Sbjct: 439 LELDSYSRVFFPTSFLLFNLVYWVGYL 465
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 367 bits (941), Expect = e-101
Identities = 207/462 (44%), Positives = 277/462 (59%), Gaps = 64/462 (13%)
Query: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
+V+ IL+NLLEGYDN+LRP G T + TD+YV S GPV+ + MEYT+D+FF QTW D
Sbjct: 65 DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDR 124
Query: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
RLKF ++L LN+ MV KIW PDTFFRN KK+ AH +TTPN++ RI +G +LYT+RL
Sbjct: 125 RLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 184
Query: 151 TINADCPMRLVNFPMDGHACPLKFGSYA-------------------------------- 178
TI+A+C ++L NFPMD H+CPL+F S++
Sbjct: 185 TIDAECQLQLHNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLAS 244
Query: 179 --------YPKSEIIYTWKKGPLYSVEVPEESS-SLLQYDLIGQTVSSETIKSNTGEYVI 229
YP+ EI+Y WK+ SVEV + S L Q+ +G ++E +K+ +G+YV+
Sbjct: 245 RVAGISDGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVV 301
Query: 230 MTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSIS 289
M+VYF L R+MGYF IQ Y PC + V+LS VSFWINK++VPART GITTVLTMTTLS
Sbjct: 302 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 361
Query: 290 ARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-TNLQTQKAKRKAQ-------- 340
AR SLPKVSY TAMD F++VCF FVFSAL+E+ ++YF +N + K K K +
Sbjct: 362 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMF 421
Query: 341 -FAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQS 399
F A PT+ I P A I + ++ HL++R + + ++
Sbjct: 422 SFKA-PTIDI----RPRSATIQM--NNATHLQERDEEYGYECLDGKDCASFFCCFEDCRT 474
Query: 400 TPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYL 441
+ +K+D Y+RI FP AF FNLVYWV YL
Sbjct: 475 GAWRHGRIHIRI---AKMDSYARIFFPTAFCLFNLVYWVSYL 513
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 318 bits (814), Expect = 8e-87
Identities = 170/440 (38%), Positives = 255/440 (57%), Gaps = 36/440 (8%)
Query: 33 SRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERL 92
SRIL+ +L YD++LRPG G T V +I V S GP+S ++MEYT+D+ F QTW DERL
Sbjct: 72 SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERL 131
Query: 93 KFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTI 152
+ E L LN +VS++W PDTFFRN K++ H +T PN++ RI ++G +LYT+R+TI
Sbjct: 132 CYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTI 191
Query: 153 NADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYDLI 211
+A C + ++ FPMD H+CPL F S++YP++E+IY W+ + +E+ E++S L Q+D
Sbjct: 192 DAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWEN---FKLEINEKNSWKLFQFDFT 248
Query: 212 GQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPA 271
G + +E I + G++++MT++F++ R+ GY Q Y P +T +LS VSFWI ES PA
Sbjct: 249 GVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPA 308
Query: 272 RTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQ 331
RT GIT+VLTMTTL +R + P+VSY TA+D++IA+CF F F AL+EFA +N+ Q
Sbjct: 309 RTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYNQ 368
Query: 332 TQ------------KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL 379
T+ ++ A+ A + E +IV S + ++
Sbjct: 369 TKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSAQQP 428
Query: 380 PIVSSSEA-----------------NKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSR 422
P S E K P + + L ++D YSR
Sbjct: 429 PSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCI---HVYRLDNYSR 485
Query: 423 ILFPVAFAGFNLVYWVVYLS 442
++FPV F FN++YW+V L+
Sbjct: 486 VVFPVTFFFFNVLYWLVCLN 505
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 280 bits (715), Expect = 2e-75
Identities = 161/416 (38%), Positives = 234/416 (56%), Gaps = 16/416 (3%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 39 SDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWND 98
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 99 PRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSI 158
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQY 208
R+T+ CPM L NFPMD C ++ S+ Y +++I+ W++ V + +L Q+
Sbjct: 159 RITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF 215
Query: 209 DLIGQTVSSETIKS-NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
L + K NTG++ + FHL+R+MGY++IQ+Y P ++ VILS +SFWIN +
Sbjct: 216 ILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMD 275
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 276 AAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 335
Query: 328 TNLQTQ--KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSS 385
+ + + +RK + P + + + E E S Y + I
Sbjct: 336 SRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNF---SAYGMGPACLQAKDGISVKG 392
Query: 386 EANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
N T P S +P + F KID+ SRI FP+AF FN+ YW++Y
Sbjct: 393 ANNSNTTNPPPAPSK--SPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 278 bits (712), Expect = 6e-75
Identities = 162/419 (38%), Positives = 242/419 (57%), Gaps = 22/419 (5%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 44 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWND 103
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 104 PRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSI 163
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWK-KGPLYSVEVPEESSSLLQ 207
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W+ + P+ E LL+
Sbjct: 164 RLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLK 223
Query: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 224 EE---KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 280
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 281 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340
Query: 328 TNLQTQ----KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL-PIV 382
+ + + KRK + A + ++ ++ E+ +S++ T+ + P +
Sbjct: 341 SRQHKELLRFRRKRKNKTEAFALEKFYRFSD-MDDEV---RESRF----SFTAYGMGPCL 392
Query: 383 SSSEANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
+ + +Q P +P + F KID SR FP+AF FN+ YWV+Y
Sbjct: 393 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 277 bits (708), Expect = 2e-74
Identities = 159/422 (37%), Positives = 236/422 (55%), Gaps = 39/422 (9%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG V++ M+Y +++F RQ W D
Sbjct: 45 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWND 104
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H++TT NKL RI +NG +LY++
Sbjct: 105 SRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSI 164
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTW-KKGPLYSVEVPEESSSLLQ 207
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W GP+ E +L+
Sbjct: 165 RLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILK 224
Query: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 225 EE---KELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 281
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVF+AL+E+AAVN+
Sbjct: 282 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV 341
Query: 328 TNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEA 387
+++ +F + + + + E + +S+++ L + +
Sbjct: 342 -------SRQHKEF-----LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGT-- 387
Query: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSK---------IDQYSRILFPVAFAGFNLVYWV 438
+++TP P P P G K ID SR FP+AF FN+ YW+
Sbjct: 388 --------AVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 439 VY 440
Y
Sbjct: 440 TY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 277 bits (708), Expect = 2e-74
Identities = 159/422 (37%), Positives = 236/422 (55%), Gaps = 39/422 (9%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG V++ M+Y +++F RQ W D
Sbjct: 45 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWND 104
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H++TT NKL RI +NG +LY++
Sbjct: 105 SRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSI 164
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTW-KKGPLYSVEVPEESSSLLQ 207
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W GP+ E +L+
Sbjct: 165 RLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILK 224
Query: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 225 EE---KELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 281
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVF+AL+E+AAVN+
Sbjct: 282 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV 341
Query: 328 TNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEA 387
+++ +F + + + + E + +S+++ L + +
Sbjct: 342 -------SRQHKEF-----LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGT-- 387
Query: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSK---------IDQYSRILFPVAFAGFNLVYWV 438
+++TP P P P G K ID SR FP+AF FN+ YW+
Sbjct: 388 --------AVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 439 VY 440
Y
Sbjct: 440 TY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 276 bits (707), Expect = 2e-74
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 39/422 (9%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 45 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWND 104
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H++TT NKL RI +NG +LY++
Sbjct: 105 SRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSI 164
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTW-KKGPLYSVEVPEESSSLLQ 207
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W GP+ E +L+
Sbjct: 165 RLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILK 224
Query: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 225 EE---KELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 281
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVF+AL+E+AAVN+
Sbjct: 282 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV 341
Query: 328 TNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEA 387
+++ +F + + + + E + +S+++ L + +
Sbjct: 342 -------SRQHKEF-----LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGT-- 387
Query: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSK---------IDQYSRILFPVAFAGFNLVYWV 438
+++TP P P P G K ID SR FP+AF FN+ YW+
Sbjct: 388 --------AVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
Query: 439 VY 440
Y
Sbjct: 440 TY 441
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 276 bits (707), Expect = 2e-74
Identities = 162/419 (38%), Positives = 234/419 (55%), Gaps = 37/419 (8%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 44 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWND 103
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 104 PRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSI 163
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWK-KGPLYSVEVPEESSSLLQ 207
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W+ + P+ E LL+
Sbjct: 164 RLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLK 223
Query: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 224 EE---KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 280
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 281 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340
Query: 328 TNLQTQ----KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL-PIV 382
+ + + KRK +K E E+ T+ + P +
Sbjct: 341 SRQHKELLRFRRKRK-----------NKDDEVRESRF------------SFTAYGMGPCL 377
Query: 383 SSSEANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
+ + +Q P +P + F KID SR FP+AF FN+ YWV+Y
Sbjct: 378 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 272 bits (696), Expect = 4e-73
Identities = 161/416 (38%), Positives = 231/416 (55%), Gaps = 24/416 (5%)
Query: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 39 SDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWND 98
Query: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 99 PRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSI 158
Query: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQY 208
R+T+ CPM L NFPMD C ++ S+ Y +++I+ W++ V + +L Q+
Sbjct: 159 RITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVA---DGLTLPQF 215
Query: 209 DLIGQTVSSETIKS-NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
L + K NTG++ + FHL+R+MGY++IQ+Y P ++ VILS +SFWIN +
Sbjct: 216 ILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMD 275
Query: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 276 AAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 335
Query: 328 TNLQTQ--KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSS 385
+ + + +RK + K E E S Y + I
Sbjct: 336 SRQHKELLRFRRKRRH--------HKEDEAGEGRFNF---SAYGMGPACLQAKDGISVKG 384
Query: 386 EANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
N T P S +P + F KID+ SRI FP+AF FN+ YW++Y
Sbjct: 385 ANNSNTTNPPPAPSK--SPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 263 bits (671), Expect = 3e-70
Identities = 151/444 (34%), Positives = 231/444 (52%), Gaps = 41/444 (9%)
Query: 32 VSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDER 91
V +D LL+GYD RLRP FGG +V I V S VS+V M+YT+ ++F+Q+W D+R
Sbjct: 37 VKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKR 96
Query: 92 LKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLT 151
L + G L+L+N + ++W PDT+F N KKS H +T N++ R+ +GT+LY +R+T
Sbjct: 97 LSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 152 INADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGP-----LYSVEVPEESSSLL 206
A C M L +P+D C L+ SY Y +I + W G + +E+P
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELP------- 209
Query: 207 QYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINK 266
Q+ ++ + S+ ++ TG Y +++ F L+R +GYF++Q Y P + ILS VSFWIN
Sbjct: 210 QFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINY 269
Query: 267 ESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNY 326
++ AR GITTVLTMTT+S R +LPK+ Y A+D ++ CF FVF AL+E+A VNY
Sbjct: 270 DASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNY 329
Query: 327 F-----------------TNLQTQKAKRKAQFAAPPTV---TISKATEPLEAEIVLHPDS 366
N + + K Q A + T+ E +E++
Sbjct: 330 IFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSD 389
Query: 367 KYHLKKRITSLSL----PIVSSSEANKVLTRAPILQSTPVTPPPLS-----PAFGGTSKI 417
S S+ P+ S + L R + + P + I
Sbjct: 390 PKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSI 449
Query: 418 DQYSRILFPVAFAGFNLVYWVVYL 441
D++SR+ FP+ F+ FN+VYW+ Y+
Sbjct: 450 DKWSRMFFPITFSLFNVVYWLYYV 473
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 261 bits (667), Expect = 9e-70
Identities = 160/453 (35%), Positives = 244/453 (53%), Gaps = 56/453 (12%)
Query: 32 VSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDER 91
V +D LL+GYD RLRP FGG V +I + S VS+V M+YT+ ++F+Q W D+R
Sbjct: 36 VKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKR 95
Query: 92 LKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLT 151
L + L+L+N + ++W PDT+F N KKS H +T N++ R+ +GT+LY +R+T
Sbjct: 96 LSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 155
Query: 152 INADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGP-----LYSVEVPEESSSLL 206
A C M L +P+D C L+ SY Y +I + W+ + +E+P+ S++
Sbjct: 156 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQ--FSIV 213
Query: 207 QYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINK 266
Y LI ++ + +TG Y +++ F L+R +GYF++Q Y P I+ ILS VSFWIN
Sbjct: 214 DYKLI-----TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINY 268
Query: 267 ESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNY 326
++ AR GITTVLTMTT++ R +LPK+ Y A+D ++ CF FVF AL+E+A VNY
Sbjct: 269 DASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNY 328
Query: 327 -FTNLQTQKAKRKAQFAAP---------------------PTVTISKATEPLEAEIVLHP 364
F Q+ K+ A+ AA T+ I EA + L
Sbjct: 329 IFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGD 388
Query: 365 DSKYHLKKRITSL-----SLPIVS----------SSEANKVLTRAPILQSTPVTPPPLSP 409
L +S+ LP S + + +++ RA L+ +T P L+
Sbjct: 389 PRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLK---ITIPDLT- 444
Query: 410 AFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLS 442
+ ID++SRI FPV F+ FN+VYW+ Y++
Sbjct: 445 ---DVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 254 bits (648), Expect = 1e-67
Identities = 138/349 (39%), Positives = 201/349 (57%), Gaps = 8/349 (2%)
Query: 1 MASSLPWLCIILWLENALGKLEVEGNFYSEN-----VSRILDNLLEGYDNRLRPGFGGAV 55
M S L L + +WL LG E ++ V +D LL+GYD RLRP FGG
Sbjct: 1 MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP 60
Query: 56 TEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPD 115
V +I + S VS+V M+YT+ ++F+Q W D+RL + G L+L+N + ++W PD
Sbjct: 61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD 120
Query: 116 TFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFG 175
T+F N KKS H +T N++ R+ +GT+LY +R+T A C M L +P+D C L+
Sbjct: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180
Query: 176 SYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFH 235
SY Y +I + W+ G V E L Q+ ++ + S + TG Y +++ F
Sbjct: 181 SYGYTTDDIEFYWRGGDKAVTGV--ERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFR 238
Query: 236 LQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLP 295
L+R +GYF++Q Y P I+ ILS VSFWIN ++ AR GITTVLTMTT++ R +LP
Sbjct: 239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLP 298
Query: 296 KVSYATAMDWFIAVCFAFVFSALIEFAAVNY-FTNLQTQKAKRKAQFAA 343
K+ Y A+D ++ CF FVF AL+E+A VNY F Q+ K+ A+ A
Sbjct: 299 KIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA 347
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 27/79 (34%)
Query: 364 PDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRI 423
P K HL++R + L + I ++ N ID++SRI
Sbjct: 422 PHKKTHLRRRSSQLKIKIPDLTDVNA---------------------------IDRWSRI 454
Query: 424 LFPVAFAGFNLVYWVVYLS 442
+FP F+ FNLVYW+ Y++
Sbjct: 455 VFPFTFSLFNLVYWLYYVN 473
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 253 bits (647), Expect = 2e-67
Identities = 149/414 (35%), Positives = 234/414 (56%), Gaps = 23/414 (5%)
Query: 40 LEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPT- 98
++ +D +RP FGG V D+ V S +S+V+M++TM ++ R W DERL F +
Sbjct: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
Query: 99 EILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPM 158
+ ++ + +V KIW PD FF + K+S H+ TT N + R+ +G +LY+MR+T+ A C M
Sbjct: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
Query: 159 RLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQ--TVS 216
+FP+D C L+ SYAY +++ WK G S++ +E SL Q+ LI + T S
Sbjct: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGD-ESLKT-DEKISLSQF-LIQKFHTTS 262
Query: 217 SETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFG 276
S+TG Y + + F L+R + +F++Q Y P + V+LS VSFWI++ +VPAR G
Sbjct: 263 RLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 322
Query: 277 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAK 336
ITTVLTMTT+ S+P+VSY A+D ++ V F FVF +++E+AAVNY T +Q +K +
Sbjct: 323 ITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERK-E 381
Query: 337 RKAQFAAP--------PTVTISKATEPLEAEIVLHPDSKYHL--KKRITSLSLPIVSSSE 386
RK + P T+ + + EA + + L ++R + + + S E
Sbjct: 382 RKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGE 441
Query: 387 ANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
AN + + T F T ID+YSR++FP ++ FNL+YW V+
Sbjct: 442 ANAARKKGLLKGQTGFR------IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,079,298
Number of Sequences: 37866
Number of extensions: 665023
Number of successful extensions: 2137
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1974
Number of HSP's gapped (non-prelim): 111
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.