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Search of human proteins with 156766050
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
(5795 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 1.138e+04 0.0
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] 1810 0.0
gi|116686120 periaxin isoform 2 [Homo sapiens] 216 7e-55
gi|13491172 periaxin isoform 1 [Homo sapiens] 105 2e-21
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 84 5e-15
gi|110349719 titin isoform N2-A [Homo sapiens] 76 8e-13
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 66 9e-10
gi|91982772 mucin 17 [Homo sapiens] 62 1e-08
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 52 1e-05
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 52 1e-05
gi|226437579 NAC alpha domain containing [Homo sapiens] 52 2e-05
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 52 2e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 50 9e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 1e-04
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 49 1e-04
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 49 2e-04
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 49 2e-04
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 49 2e-04
gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens] 47 4e-04
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 47 6e-04
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] 47 6e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 7e-04
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ... 47 7e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 7e-04
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 46 0.001
gi|7662162 ALEX2 protein [Homo sapiens] 46 0.001
gi|29540562 ALEX2 protein [Homo sapiens] 46 0.001
gi|148746195 trichohyalin [Homo sapiens] 45 0.002
gi|112421108 capicua homolog [Homo sapiens] 45 0.002
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 45 0.003
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 1.138e+04 bits (29521), Expect = 0.0
Identities = 5795/5795 (100%), Positives = 5795/5795 (100%)
Query: 1 MCDCFHMVLPTWPGTPGSVSGRQLQPGEPGAETEDDHSVTEGPADEGIRPRPQGSSPVYE 60
MCDCFHMVLPTWPGTPGSVSGRQLQPGEPGAETEDDHSVTEGPADEGIRPRPQGSSPVYE
Sbjct: 1 MCDCFHMVLPTWPGTPGSVSGRQLQPGEPGAETEDDHSVTEGPADEGIRPRPQGSSPVYE 60
Query: 61 YTTEAADFGLQEDAPGRQGSAGRRRSWWKRDSGDSRTFFRMSRPEAVQEATEVTLKTEVE 120
YTTEAADFGLQEDAPGRQGSAGRRRSWWKRDSGDSRTFFRMSRPEAVQEATEVTLKTEVE
Sbjct: 61 YTTEAADFGLQEDAPGRQGSAGRRRSWWKRDSGDSRTFFRMSRPEAVQEATEVTLKTEVE 120
Query: 121 AGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFENIKYEDALKILQY 180
AGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFENIKYEDALKILQY
Sbjct: 121 AGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFENIKYEDALKILQY 180
Query: 181 SEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQE 240
SEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQE
Sbjct: 181 SEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQE 240
Query: 241 RLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDT 300
RLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDT
Sbjct: 241 RLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDT 300
Query: 301 EAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELG 360
EAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELG
Sbjct: 301 EAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELG 360
Query: 361 PWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLH 420
PWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLH
Sbjct: 361 PWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLH 420
Query: 421 GKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPP 480
GKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPP
Sbjct: 421 GKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPP 480
Query: 481 EIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPG 540
EIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPG
Sbjct: 481 EIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPG 540
Query: 541 REPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKT 600
REPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKT
Sbjct: 541 REPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKT 600
Query: 601 GREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKE 660
GREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKE
Sbjct: 601 GREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKE 660
Query: 661 QILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKT 720
QILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKT
Sbjct: 661 QILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKT 720
Query: 721 TDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDL 780
TDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDL
Sbjct: 721 TDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDL 780
Query: 781 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKM 840
KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKM
Sbjct: 781 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKM 840
Query: 841 PSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVK 900
PSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVK
Sbjct: 841 PSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVK 900
Query: 901 LPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVS 960
LPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVS
Sbjct: 901 LPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVS 960
Query: 961 LPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL 1020
LPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL
Sbjct: 961 LPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL 1020
Query: 1021 VDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGH 1080
VDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGH
Sbjct: 1021 VDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGH 1080
Query: 1081 LPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKL 1140
LPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKL
Sbjct: 1081 LPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKL 1140
Query: 1141 DSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLP 1200
DSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLP
Sbjct: 1141 DSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLP 1200
Query: 1201 SMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVD 1260
SMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVD
Sbjct: 1201 SMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVD 1260
Query: 1261 LKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKD 1320
LKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKD
Sbjct: 1261 LKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKD 1320
Query: 1321 VTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQP 1380
VTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQP
Sbjct: 1321 VTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQP 1380
Query: 1381 PSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDL 1440
PSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDL
Sbjct: 1381 PSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDL 1440
Query: 1441 KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKM 1500
KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKM
Sbjct: 1441 KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKM 1500
Query: 1501 PSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVK 1560
PSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVK
Sbjct: 1501 PSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVK 1560
Query: 1561 LPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMS 1620
LPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMS
Sbjct: 1561 LPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMS 1620
Query: 1621 LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEAS 1680
LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEAS
Sbjct: 1621 LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEAS 1680
Query: 1681 VDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGH 1740
VDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGH
Sbjct: 1681 VDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGH 1740
Query: 1741 LPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKL 1800
LPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKL
Sbjct: 1741 LPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKL 1800
Query: 1801 DSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLP 1860
DSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLP
Sbjct: 1801 DSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLP 1860
Query: 1861 SMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVD 1920
SMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVD
Sbjct: 1861 SMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVD 1920
Query: 1921 LKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKD 1980
LKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKD
Sbjct: 1921 LKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKD 1980
Query: 1981 MTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQP 2040
MTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQP
Sbjct: 1981 MTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQP 2040
Query: 2041 PSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDL 2100
PSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDL
Sbjct: 2041 PSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDL 2100
Query: 2101 KDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKM 2160
KDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKM
Sbjct: 2101 KDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKM 2160
Query: 2161 PSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVK 2220
PSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVK
Sbjct: 2161 PSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVK 2220
Query: 2221 LLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVS 2280
LLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVS
Sbjct: 2221 LLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVS 2280
Query: 2281 LPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEAS 2340
LPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEAS
Sbjct: 2281 LPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEAS 2340
Query: 2341 ADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGH 2400
ADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGH
Sbjct: 2341 ADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGH 2400
Query: 2401 LPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKL 2460
LPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKL
Sbjct: 2401 LPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKL 2460
Query: 2461 DGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLS 2520
DGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLS
Sbjct: 2461 DGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLS 2520
Query: 2521 SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMD 2580
SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMD
Sbjct: 2521 SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMD 2580
Query: 2581 LKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKG 2640
LKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKG
Sbjct: 2581 LKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKG 2640
Query: 2641 VTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQP 2700
VTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQP
Sbjct: 2641 VTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQP 2700
Query: 2701 PSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDL 2760
PSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDL
Sbjct: 2701 PSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDL 2760
Query: 2761 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKM 2820
KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKM
Sbjct: 2761 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKM 2820
Query: 2821 PSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVK 2880
PSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVK
Sbjct: 2821 PSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVK 2880
Query: 2881 LPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVS 2940
LPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVS
Sbjct: 2881 LPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVS 2940
Query: 2941 LPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVS 3000
LPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVS
Sbjct: 2941 LPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVS 3000
Query: 3001 VDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGH 3060
VDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGH
Sbjct: 3001 VDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGH 3060
Query: 3061 LPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKL 3120
LPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKL
Sbjct: 3061 LPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKL 3120
Query: 3121 DGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLP 3180
DGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLP
Sbjct: 3121 DGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLP 3180
Query: 3181 SMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVD 3240
SMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVD
Sbjct: 3181 SMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVD 3240
Query: 3241 RKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKD 3300
RKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKD
Sbjct: 3241 RKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKD 3300
Query: 3301 VTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQL 3360
VTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQL
Sbjct: 3301 VTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQL 3360
Query: 3361 PSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL 3420
PSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL
Sbjct: 3361 PSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL 3420
Query: 3421 KVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKM 3480
KVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKM
Sbjct: 3421 KVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKM 3480
Query: 3481 PSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE 3540
PSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE
Sbjct: 3481 PSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE 3540
Query: 3541 LLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVS 3600
LLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVS
Sbjct: 3541 LLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVS 3600
Query: 3601 LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEAS 3660
LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEAS
Sbjct: 3601 LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEAS 3660
Query: 3661 VDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEH 3720
VDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEH
Sbjct: 3661 VDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEH 3720
Query: 3721 LPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKL 3780
LPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKL
Sbjct: 3721 LPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKL 3780
Query: 3781 DSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLP 3840
DSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLP
Sbjct: 3781 DSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLP 3840
Query: 3841 SMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVD 3900
SMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVD
Sbjct: 3841 SMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVD 3900
Query: 3901 LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD 3960
LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD
Sbjct: 3901 LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD 3960
Query: 3961 MTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQP 4020
MTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQP
Sbjct: 3961 MTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQP 4020
Query: 4021 PSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL 4080
PSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL
Sbjct: 4021 PSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL 4080
Query: 4081 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKM 4140
KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKM
Sbjct: 4081 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKM 4140
Query: 4141 PSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVK 4200
PSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVK
Sbjct: 4141 PSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVK 4200
Query: 4201 LPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVS 4260
LPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVS
Sbjct: 4201 LPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVS 4260
Query: 4261 LPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEAS 4320
LPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEAS
Sbjct: 4261 LPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEAS 4320
Query: 4321 LDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGH 4380
LDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGH
Sbjct: 4321 LDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGH 4380
Query: 4381 LPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKL 4440
LPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKL
Sbjct: 4381 LPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKL 4440
Query: 4441 DSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIP 4500
DSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIP
Sbjct: 4441 DSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIP 4500
Query: 4501 SMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVD 4560
SMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVD
Sbjct: 4501 SMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVD 4560
Query: 4561 LKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHED 4620
LKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHED
Sbjct: 4561 LKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHED 4620
Query: 4621 VAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDP 4680
VAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDP
Sbjct: 4621 VAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDP 4680
Query: 4681 SRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSE 4740
SRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSE
Sbjct: 4681 SRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSE 4740
Query: 4741 CSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVP 4800
CSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVP
Sbjct: 4741 CSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVP 4800
Query: 4801 RAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQV 4860
RAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQV
Sbjct: 4801 RAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQV 4860
Query: 4861 SFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQ 4920
SFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQ
Sbjct: 4861 SFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQ 4920
Query: 4921 GPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECS 4980
GPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECS
Sbjct: 4921 GPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECS 4980
Query: 4981 VEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSL 5040
VEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSL
Sbjct: 4981 VEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSL 5040
Query: 5041 PQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFA 5100
PQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFA
Sbjct: 5041 PQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFA 5100
Query: 5101 KPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQ 5160
KPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQ
Sbjct: 5101 KPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQ 5160
Query: 5161 PSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQTQA 5220
PSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQTQA
Sbjct: 5161 PSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQTQA 5220
Query: 5221 PAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKL 5280
PAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKL
Sbjct: 5221 PAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKL 5280
Query: 5281 HLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASM 5340
HLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASM
Sbjct: 5281 HLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASM 5340
Query: 5341 EDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPS 5400
EDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPS
Sbjct: 5341 EDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPS 5400
Query: 5401 SEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPI 5460
SEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPI
Sbjct: 5401 SEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPI 5460
Query: 5461 SKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSL 5520
SKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSL
Sbjct: 5461 SKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSL 5520
Query: 5521 LKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSS 5580
LKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSS
Sbjct: 5521 LKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSS 5580
Query: 5581 VNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESK 5640
VNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESK
Sbjct: 5581 VNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESK 5640
Query: 5641 KSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFP 5700
KSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFP
Sbjct: 5641 KSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFP 5700
Query: 5701 KLGFSSSPTKKSKSTEDGAELEEQKLQEETITFFDARESFSPEEKEEGELIGPVGTGLDS 5760
KLGFSSSPTKKSKSTEDGAELEEQKLQEETITFFDARESFSPEEKEEGELIGPVGTGLDS
Sbjct: 5701 KLGFSSSPTKKSKSTEDGAELEEQKLQEETITFFDARESFSPEEKEEGELIGPVGTGLDS 5760
Query: 5761 RVMVTSAARTELILPEQDRKADDESKGSGLGPNEG 5795
RVMVTSAARTELILPEQDRKADDESKGSGLGPNEG
Sbjct: 5761 RVMVTSAARTELILPEQDRKADDESKGSGLGPNEG 5795
>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
Length = 5890
Score = 1810 bits (4689), Expect = 0.0
Identities = 1694/5939 (28%), Positives = 2673/5939 (45%), Gaps = 1310/5939 (22%)
Query: 437 KPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAF 496
KPR + G+ EG+ QS I + R T + + G +I D+ +P+F
Sbjct: 130 KPRLKSEDGV--EGDLGETQSRTITVTRRVTAYTVDVTGREGAKDI-----DISSPEFKI 182
Query: 497 STEK---------EPERERRLSTPQRGKRQDASSKAGTGL---------KGEEVEGAGW- 537
+ + E + + + A+S G+ + G E++GAG
Sbjct: 183 KIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHS 242
Query: 538 -----MPGRE---PTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTE-----------G 578
MPG + + A+G + G G+Q + G E G
Sbjct: 243 KLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHG 302
Query: 579 QIRMPKFKIPSLGWSPSKH---TKTGREKATEDTEQGREGEATATADRREQRRTE----- 630
+I+ P K+P G S + K G + + G +G + Q
Sbjct: 303 KIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSAN 362
Query: 631 -EGLKDKEDSDSMT---------------------NTTKIQLIHDEKRLKKEQILTEKEV 668
EGL+ K +T + + Q+ E + +V
Sbjct: 363 IEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDIDV 422
Query: 669 ATKDSKFKMPKFKMPLFGASAPGKSMEASVD-------VSAPKVEADVSLL--------- 712
SK +PK K+P F S K E +D V+ P V DVSL
Sbjct: 423 QGPGSKLNVPKMKVPKFSVSG-AKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
Query: 713 SMQG-DLKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKV 771
M+G +KT ++ +Q P ++ DV L G +K P VQ +K P+V
Sbjct: 482 KMKGTKVKTPEMIIQKPKISMQ------DVDLSLGSPKLKGDIKVSAPGVQ-GDVKGPQV 534
Query: 772 DLKGPKLDLKGPKAE--VTAPDV----------KMSLSSMEVDVQAPRAK----LDGARL 815
LKG ++D++ P E +T P + ++S+S ++++V AP+ K + R+
Sbjct: 535 ALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRV 594
Query: 816 EG--------------DLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSME-------- 853
EG D+S D E + KMPK KMP+F S PG E
Sbjct: 595 EGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTF--STPGAKGEGPDVHMTL 652
Query: 854 --DSVDVSAPKVEA---DVSLSSMQGDLKATDL----------SIQPPSADLEVQA---- 894
+ +S PKV DV+L + G LK D+ I P DL V+
Sbjct: 653 PKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVK 712
Query: 895 GQVDVKLP-------------EGPVPEGAGPKVHL--PKVEMPSFKMPKVDLKGPQIDVK 939
G+ DV +P + P + GP HL PK++MP F +P +GP++DV
Sbjct: 713 GEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVN 772
Query: 940 GPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSK 997
PK +D+ GPK +VTAPD VS+ E ++ K K+ +
Sbjct: 773 LPKADVDISGPKIDVTAPD--VSIEEPEGKLKGPKFKM------------------PEMN 812
Query: 998 FKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLP-----SMQGDLKTTDLSIQPAS 1052
K+PK MP + G ++K DV+ PKVE+++ +P S + D+ D+ +Q
Sbjct: 813 IKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPD 872
Query: 1053 TDLKV---------------QADQVDVKLPEGHLP----------EGAGLKGHLPKVEMP 1087
LK+ + +VDV LP+ + ++G K++ P
Sbjct: 873 WHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGP 932
Query: 1088 SFKMPKVALKGPQVD-------VKGPKL-------------DLKSPKAEVTAPDVEV--- 1124
FKMP++ +K P++ +KGPK+ DLK PK +V+APDVE+
Sbjct: 933 KFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGP 992
Query: 1125 --------------SLPSV-----EVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKM 1165
S+PS+ E DV A +D + + + + D + + + K
Sbjct: 993 DWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKG 1052
Query: 1166 PKFKMPSFGASAPGKSI-EASVDVSAPKVE--ADVSLPSMQGDLKTTDLSIQPPSADLEV 1222
PKFKMP AP S+ + +D+ PK++ D+S P ++G+++ D+ I+ P D++
Sbjct: 1053 PKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKA 1112
Query: 1223 HAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEV 1282
+EG +G + +PK++MP MP + +GP+V+V PK D
Sbjct: 1113 PD-------VEG---QGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKAD-------- 1154
Query: 1283 TAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSA 1342
V VS P +VD++AP L+G + L + FK PK MP +
Sbjct: 1155 ----VVVSGP--KVDIEAPDVSLEGP----EGKLKGPKFKMPEMHFKTPKISMPDVDLHL 1204
Query: 1343 PGKSIEASVDLSAPKVEADMSLPSMQ-----GDLKTTDLSIQPPSTDLEL---------- 1387
G ++ VD+S PKVE +M +P ++ D+ D+ +Q P L++
Sbjct: 1205 KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSM 1264
Query: 1388 -----QAGQLDVKLPE------GP-----VPEGAGLKGHLPKLQMPSFKVPKVDLKGPEI 1431
+ ++DV LP+ GP VP+ L+G KL+ P FK+P++ K P+I
Sbjct: 1265 PGFKGEGREVDVNLPKADIDVSGPKVDVEVPD-VSLEGPEGKLKGPKFKMPEMHFKAPKI 1323
Query: 1432 DIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDS 1491
+ L+LK PK++ DV+VSLP VE +++ P + G ++ D+S D D+ D
Sbjct: 1324 SMPDVDLNLKGPKLK---GDVDVSLPEVEGEMKVPDVDIKGPKV--DISAPDVDVHGPDW 1378
Query: 1492 KFKMPKFKMPSFGVSAPG-KSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADL 1550
KMPK KMP F S PG K VDV PK + DVS P M D + D++I+ P A L
Sbjct: 1379 HLKMPKVKMPKF--SMPGFKGEGPEVDVKLPKADVDVSGPKM--DAEVPDVNIEGPDAKL 1434
Query: 1551 --------EVQAGQVDVKLPE-GPVSEGAGLKGH----LPKVQMPSFKMPKVDLKGPQID 1597
E+ + +P+ G +G +KG +PKV+ K P VD+KGP++D
Sbjct: 1435 KGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVE-GEIKAPDVDIKGPKVD 1493
Query: 1598 VKGPKLDLKGPKVEVTAPDVKMSLSSM--------EVDVQAPRAKLDGAQLEGDLSLADK 1649
+ P +++ GP + P VKM SM EVD+ P+A L + + D+ + D
Sbjct: 1494 INAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDV 1553
Query: 1650 AVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSEPKV--EADVSLPSMQGDLKTTDL 1706
+ A + K K PKFKMPS + S+ + +++ PK+ + DVSLP ++GDLK ++
Sbjct: 1554 NLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEI 1613
Query: 1707 SIQSPSADLEVQAGQVNVKLPEGPLPEGAGFK-----GHLPKVQMPS----LKMPKV--- 1754
+++P D+ V G ++++ PEG L +G FK PK+ MP LK PKV
Sbjct: 1614 DVKAPKMDVNV--GDIDIEGPEGKL-KGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD 1670
Query: 1755 ----------ALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSV--------------- 1789
+K P +D+KGPK+D+ P EV PD + +P +
Sbjct: 1671 MDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGP 1730
Query: 1790 EVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDV 1848
EVDV P A +D D D D+ + K K KFKMP + AP S+ + +++
Sbjct: 1731 EVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNL 1790
Query: 1849 SAPKVEAEV--SLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHL 1906
PK++ E+ S+P ++GDL+ + + P + + VD++ P+ A LKG
Sbjct: 1791 KGPKLKGEIDASVPELEGDLRGPQVDVKGPFVE--AEVPDVDLECPD------AKLKG-- 1840
Query: 1907 PKVDMPS--FKMPKVD-------LKGPQ----TDVKGAKL--DLKGPKAEVTAPDVE--- 1948
PK MP FK PK+ LKGP+ DV KL DL GP V PDVE
Sbjct: 1841 PKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELEC 1900
Query: 1949 ---------------------VSLPSMEVDVQAQKAKLD----GARLEGDLS-------L 1976
+S+P +++ ++ K K D +LEGDL+ +
Sbjct: 1901 PDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEV 1960
Query: 1977 ADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSMQGDLKT 2033
D ++ D+K K PKFKMP P S+ + + + PKV + DVS+P ++G++K
Sbjct: 1961 PDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKV 2020
Query: 2034 TDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDI 2093
D+ I+ P D + VDV P+ H+ +PK++MP MP +GP+VD+
Sbjct: 2021 PDVDIKGPKMD--IDAPDVDVHGPDWHL--------KMPKMKMPKFSMPGFKAEGPEVDV 2070
Query: 2094 KGPKLD--LKDPKVEMRVPDV------------------------EVSLPSMEVDVQAPR 2127
PK D + PKV++ VPDV ++S+P +++ ++ P+
Sbjct: 2071 NLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPK 2130
Query: 2128 AKLD----SAHLQGDLT-------LANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EAS 2175
K D L+GDLT + + +L D+K K PKFKMP P S+ + +
Sbjct: 2131 VKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVN 2190
Query: 2176 VDVSPPKVEADM--SLPSMQGDLKTTDLSIQPLSADV----------------------- 2210
+++ PKV+ DM S+P ++G++K D+ I+ D+
Sbjct: 2191 LNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPK 2250
Query: 2211 ------KVQAGQVDVKL------LEGP-----VPEEVGLKGHLPKLQMPSFKVPKVDLKG 2253
K + +VDV L + GP VP +V L+G KL+ P FK+P++ K
Sbjct: 2251 FSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVP-DVSLEGPEGKLKGPKFKMPEMHFKT 2309
Query: 2254 PEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTA 2313
P+I + +LK PK++ DV+VS P +E ++K P + G +L+ DM + V
Sbjct: 2310 PKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPELDVKGPKLDADM--PEVAVEG 2364
Query: 2314 KDSKFKMPKFKMLSFGVSALGKS---IEASADVSALKVEADVSLPSMQGDLKTTDLSVQP 2370
+ K+K PKFKM A S ++ K E DV +P ++GDLK + V
Sbjct: 2365 PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSG 2424
Query: 2371 PSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDL 2430
P +D++ PEG KL+ P FKMP + K P I + L+L
Sbjct: 2425 P---------DIDIEGPEG-------------KLKGPKFKMPDMHFKAPNISMPDVDLNL 2462
Query: 2431 KGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKM 2490
KGPK + DV+VS P VE +E P + G + V DV D K+PK KM
Sbjct: 2463 KGPK---IKGDVDVSVPEVEGKLEVPDMNIRGP----KVDVNAPDVQAPDWHLKMPKMKM 2515
Query: 2491 PSFGVSAPGKSIEA-SVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADL---EVQAGQ 2546
P F S PG E VDV+ PK + D +S + D++ D++I+ P L +++ +
Sbjct: 2516 PKF--SMPGFKAEGPEVDVNLPKADVD--ISGPKVDIEGPDVNIEGPEGKLKGPKLKMPE 2571
Query: 2547 VDVKLPEGPVPE------GAGLKG----HLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLK 2596
+++K P+ +P+ G +KG LPKV+ K PE+D+KGP++D+ P + ++
Sbjct: 2572 MNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVE-GDLKGPEVDIKGPKVDINAPDVGVQ 2630
Query: 2597 GPKAEVTAPDVEMSLSSM--------EVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKF 2648
GP + P V+M SM + DV+ P+A +D + + D+ D + + K
Sbjct: 2631 GPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKL 2690
Query: 2649 KMPKFKMPSFRVSAPGES---IEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQL 2705
K PKFKMP + AP S I+ + ++K + D+SLP ++GDLK ++ I+ P ++
Sbjct: 2691 KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP--KV 2748
Query: 2706 EVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFK-----------MPEVDLKGPQIDVK 2754
++ A VDV P+ H+ K +PK+ MP FK ++D+ GP++DV+
Sbjct: 2749 DIDAPDVDVHGPDWHLKMP---KIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVE 2805
Query: 2755 GPNVDLKGPKAEVTAPDVKM----------SLSSMEVDVQAPRAKLD----GARLEGDL- 2799
P+V+++GP+ + +P KM S+ +++++ P+ K D G ++EGDL
Sbjct: 2806 CPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLK 2865
Query: 2800 -------------SLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEA-SVDVSELKVEA 2845
+ D + D KMPK KMP F S PG E VDV+ K +
Sbjct: 2866 GPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADV 2923
Query: 2846 DGSFPSMQGDLKTTDIRIQPPSAQL---EVQAGQVDVKLPEGHVPE-GAGLKGHLPKVQM 2901
D S P + D++ D+ I+ P +L + + ++++K P+ +P+ LKG PKV+
Sbjct: 2924 DVSGPKV--DVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKG--PKVKG 2979
Query: 2902 P-SFKMPKV--DLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSV-------------- 2944
+PKV DLKGP++D++GP++D+ P V PD + +P V
Sbjct: 2980 DVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEG 3039
Query: 2945 -EVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVD 3002
+VDV P+A LD + + D+ + D ++ + K K PKFKMP + AP S+ ++ ++
Sbjct: 3040 PDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLN 3099
Query: 3003 VSAPKV--EAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGH 3060
+ PKV + +VSLP ++GD+K D+ I+ P ++++ A VD++ P+ H+
Sbjct: 3100 LKGPKVKGDMDVSLPKVEGDMKVPDVDIKGP--KVDINAPDVDVQGPDWHL--------K 3149
Query: 3061 LPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTAPDVEVSQPGM--------- 3109
+PK++MP MP +GP++DV PK LD+ GPK DV PDV + P
Sbjct: 3150 MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKM 3209
Query: 3110 -EVDVEAP------------GAKLDG------ARLEGDL--------------SLADKDV 3136
E++++AP G K+ G A +EGDL D D+
Sbjct: 3210 PEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDI 3269
Query: 3137 TAKDSKFKMPKFKMPSFGVSAP------------GKSIEVLVDVSAPKVEADLSLPSMQG 3184
D+K K PK KMP V+ P G ++ VDVS PK+E D+ PS+
Sbjct: 3270 HGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSL-- 3327
Query: 3185 DLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGP 3244
D+K ++ + P +E ++ + KLP+ +G K P++ + K P +D GP
Sbjct: 3328 DIKGPEVDVSGPKLNIEGKSKKSRFKLPK---FNFSGSKVQTPEVDVKG-KKPDIDITGP 3383
Query: 3245 QIDIKGPKLDLKG---------PKMDVTAPDVEVSQPSMEVDVEAPGAKLD----GARLE 3291
++DI P ++++G P + +++P +VS P +E+++++P K D G LE
Sbjct: 3384 KVDINAPDVEVQGKVKGSKFKMPFLSISSP--KVSMPDVELNLKSPKVKGDLDIAGPNLE 3441
Query: 3292 GD--------------LSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPK 3337
GD L+ D DV D KMPK KMP + S K+ V V PK
Sbjct: 3442 GDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGL-KAEGPDVAVDLPK 3500
Query: 3338 AEADVSLPSMQGDLKTTDLSIQLPSVDL---EVQAGQVDVKLPEGHVPE-GAGLKGHLPK 3393
+ ++ PSM +++ DL+++ P L + + +++K P+ +P+ LKG PK
Sbjct: 3501 GDINIEGPSM--NIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKG--PK 3556
Query: 3394 VEMP-SFKMPKV--DLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLPSV----------- 3439
V+ +PK+ DLK P+VDIKGPK+D+ P +V PD + +P V
Sbjct: 3557 VKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFK 3616
Query: 3440 ----EVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSI-EA 3494
EVDV P+A +D + D+ + + ++ D+K K PKFKMP + AP S+ +
Sbjct: 3617 GEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDF 3676
Query: 3495 SLDVSAPKVEAD--VSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE--LLEGPVPEGA 3550
L++ PK++ D VSL ++GDLK ++ I+ P D++ + ++ +GP +
Sbjct: 3677 DLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIP 3736
Query: 3551 GLKGHLPKVEMP----SLKTPKV-------------DLKGPQIDVKGPKLDLKGPKAEVR 3593
+ PK+ MP +LK PKV DLKGP++D+KGPK+D+ P +V+
Sbjct: 3737 EMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQ 3796
Query: 3594 VPDVEVSLPSV---------------EVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKF 3638
PD + +P V +VDV PKA LD + D+ + D ++ + K
Sbjct: 3797 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKL 3856
Query: 3639 KMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTTDLSIQPPSADL 3695
K PKFKMP + AP SM + +++ PKV + DVSLP ++GD++ DL I+ P D
Sbjct: 3857 KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD- 3915
Query: 3696 KVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKA 3755
+ A +DV+ P+ + +PK++MP + MP +GP+VD+ PK DL
Sbjct: 3916 -INAPDVDVRGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADL----- 3961
Query: 3756 EVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGV 3815
+V+ P V+V +P V ++ D+K K PKFKMP +
Sbjct: 3962 DVSGPKVDVDVPDVNIE-------------------------GPDAKLKGPKFKMPEMNI 3996
Query: 3816 SAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLL 3872
AP S+ + +H+ PKV + DVSLP M+GDLK ++ I+ D + A VD+
Sbjct: 3997 KAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVD--IDAPDVDVHGP 4054
Query: 3873 EGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPE---------IDIKGPKLDLKDPKVEVT 3923
+ H+ +PKV+MP F MP +GPE ID+ GPK+D+ P +++
Sbjct: 4055 DWHL--------KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIH 4106
Query: 3924 AP-------------------------------------DVEVSLPSVEVDVEAPGAKLD 3946
P DV+VSLP VE D++ P +
Sbjct: 4107 GPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIK 4166
Query: 3947 GARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPG-KSMEASVDVTAPKVEADVSLP 4005
G ++ D+ + D D+ D KMPK KMP F S PG K VDV PK + DVS P
Sbjct: 4167 GPKV--DIDVPDVDVQGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVNLPKADLDVSGP 4222
Query: 4006 SMQGDLKATDLSVQPPSADL---EVQAGQVDVKLPEGPVPE------GASLKG----HLP 4052
+ D+ D++++ P A L + + ++++K P+ +P+ G +KG LP
Sbjct: 4223 KV--DIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLP 4280
Query: 4053 KVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSM--------EVDVQ 4104
KV+ K P+VD+KGP++D+ P +D+ GP + P VKM SM +VDV
Sbjct: 4281 KVE-GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVT 4339
Query: 4105 APRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSM---EASVDVSEL 4161
P+A ++ + D+ D + D+K K PKFKMP + AP SM + ++ ++
Sbjct: 4340 LPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKV 4399
Query: 4162 KAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKG-----HL 4216
K DVSLP ++GDLK ++ I+ PS D++ V+++ PEG L KG K
Sbjct: 4400 KGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTP--DVNIEGPEGKL-KGPKFKMPEMNIKA 4456
Query: 4217 PKVQMP----CLKMPKVA-------------LKGPQVDVKGPKLDLKGPK---ADVMTPV 4256
PK+ MP LK PKV LKGP+VD++GP+ LKGPK DV
Sbjct: 4457 PKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKS 4516
Query: 4257 VEVSLPSMEVDVEAPGAKLDS----VRLEGDL--------------SLADKDMTAKDSKF 4298
++S+ ++++++ P K D +LEGDL D D+ + K
Sbjct: 4517 PQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKL 4576
Query: 4299 KMPKFKMPSFGVSAPGKSI-EASLDVSALKV--EADVSLPSMQGDLKTTHLSIQPPSADL 4355
K PKFKMP + AP S+ E L++ KV + D+SLP ++GDLK + I+ P D+
Sbjct: 4577 KGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDI 4636
Query: 4356 EVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFK---------VPK--VDLKGPQIDVN 4404
+V DV + +GP K +PK MP FK +PK +D+ GP++DV+
Sbjct: 4637 DV----PDVDV-QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVD 4691
Query: 4405 VPKLDLKGPKVEVTSP------------------------------NLDVSLPSMEVDIQ 4434
VP ++++GP ++ P ++DV+LP +E D++
Sbjct: 4692 VPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLK 4751
Query: 4435 APGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPG-KSIEVSVDVSAPKM 4493
P A + ++ D++ D DV D KMPK KMP F M PG K VDVS PK
Sbjct: 4752 GPEADIKGPKV--DINTPDVDVHGPDWHLKMPKVKMPKFSM--PGFKGEGPDVDVSLPKA 4807
Query: 4494 EADMSIPSMQGDLKTTDLRIQAPSADL---EVQAGQVDLKLPEGHMPEV-AGLKGHLPKV 4549
+ D+S P + D+ D+ I+ P A L + + ++++K P+ +P+V LKG PKV
Sbjct: 4808 DIDVSGPKV--DVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG--PKV 4863
Query: 4550 EMP-SFKMPKVD--LKGPQVDVKGPKLDLKGPKAEVMAPDV----------EVSLPSVET 4596
+ +PKV+ LKGP+VD+KGP+LD +GP A++ P + +V+ P V+
Sbjct: 4864 KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDL 4923
Query: 4597 DVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNV 4656
++AP G +LEG +V K K + P L S +++ +++
Sbjct: 4924 HLKAPKIGFSGPKLEGG------EVDLKGPKVEAPSLDV---HMDSPDINIEGPDVK-IP 4973
Query: 4657 TFHEKTSTFPIVESVVHEGDLHDPSRD-----GNLGLAVGEVGMDSKFKKLHFKVPKVSF 4711
F + F + D+ PS D L L E+ + K KK FK+PK+
Sbjct: 4974 KFKKPKFGFGAKSP---KADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHM 5030
Query: 4712 SSTKTPK-----DSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAG 4766
S K D VPG + L + + +V S P + G
Sbjct: 5031 SGPKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKS-PKTKKTMFGKMY 5089
Query: 4767 FPSSRLDLTGPHF--ESSILSPCEDVTLTKYQVTVPRAALAPE---LALEIPSGSQADIP 4821
FP D+ P F E+ + SP + L + + A+ E + + P D+
Sbjct: 5090 FPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVD 5149
Query: 4822 LPKTECSTDLQPPE-----GVPTSQAESHSGPLNS-MIPVSLGQVSFP----KFYKPKFV 4871
+ + DL+ P+ G P E + + +S QVS P PK
Sbjct: 5150 ISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIK 5209
Query: 4872 FSVPQMAV--PEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPS---PGTCVSQGPEELV 4926
VP + + P+ DL G + P +P PG + G E+
Sbjct: 5210 GDVPSVGLEGPDVDLQ-------------GPEAKIKFPKFSMPKIGIPGVKMEGGGAEVH 5256
Query: 4927 ASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKL 4986
A L + G+ D EG LK P + LPS S K +GP +D +
Sbjct: 5257 AQLPS---LEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLD----LNLKGP 5309
Query: 4987 SLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVD 5046
SL D D P +H PG + + KM+ GV +P D
Sbjct: 5310 SLKGDLDASVPSMKVH---------------APGLNLSGVG-GKMQVGGDGVKVPGIDAT 5353
Query: 5047 PSLSSAT-----AGGSFQDTEKASSD--GGRGGLGA-TASATGSEGVNLHRPQVHIPSLG 5098
L+ G S Q S D + +GA S SEG ++ P++ +P G
Sbjct: 5354 TKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKLPQFG 5412
Query: 5099 FAKP------DLRSSKAKVEVSQPEADLPL-------PKHDLSTEGDSRGCGLGDVPVSQ 5145
+ P + + + E+ P D+ L P D + EG LG
Sbjct: 5413 ISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLG------ 5466
Query: 5146 PCGEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFR 5205
GE PT L P V +E +MP ++ S
Sbjct: 5467 ATGEIKGPTVGGGL------PGIGVQGLEG------------------NLQMPGIKSSGC 5502
Query: 5206 DRGGAG---KLEVAQTQAPAATGG-------------EAAAKVKEFLVSGSNVEAAMSLQ 5249
D G KL Q P GG + + K F ++ + ++L+
Sbjct: 5503 DVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLK 5562
Query: 5250 LPEADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGD---ELSTSEVRIHPSK--G 5304
P+ S S+ DI S G + HLS G G+ +S + + SK G
Sbjct: 5563 GPKIKGGADVSGGVSAPDI------SLG-EGHLSVKGSGGEWKGPQVSSALNLDTSKFAG 5615
Query: 5305 PLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEKWSSQPEGPL----KLKAS 5360
L F P + E V G+I L PG ++ + E S + P K S
Sbjct: 5616 GLHFSGPKV---EGGVKGGQIG---LQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFS 5669
Query: 5361 STDMPSQISVVNV--------------DQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDV 5405
++ + V+V D WE+S + +K K+ +P+F+F P + V
Sbjct: 5670 GRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGV 5728
Score = 1776 bits (4599), Expect = 0.0
Identities = 1750/6238 (28%), Positives = 2758/6238 (44%), Gaps = 1431/6238 (22%)
Query: 105 EAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTV 164
E + E+ L +G+ G ++ D G+FV++V ++S AA+ ++EGDQ++ T+
Sbjct: 2 EKEETTRELLLPNWQGSGSHGLTIAQR-DDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60
Query: 165 FFENIKYEDALKILQYSEPYKVQFKIRRQ---LPAPQD----EEWASSDAQHGPQGKEKE 217
+F+N++ + ++L + V K+ R+ P P E ++S ++ G ++E
Sbjct: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120
Query: 218 DTDVADGCRETPTKTLEG-DGD----QERLISKPRVGR-------GRQSQRE-RLSWPKF 264
+ + K+ +G +GD Q R I+ R GR+ ++ +S P+F
Sbjct: 121 YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180
Query: 265 Q--------------SIKSKRGPGPQRSHSSSEAYEPR----DAHDVSPTSTDTEAQLTV 306
+ ++++ G R S S A P D + +++ E Q
Sbjct: 181 KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240
Query: 307 ERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDS- 365
+ Q PG + +N+ + G P S +G V E GP +S
Sbjct: 241 HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAV-EVQGPSLESG 299
Query: 366 -----------LEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQ---- 410
+ + G +TG RE + + + A + + + G P L PQ
Sbjct: 300 DHGKIKFPTMKVPKFGVSTG--REGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVS 357
Query: 411 ---------EGGLRAARLHGKTLEGQAQETAVAQRKPRAQ-------PTPGMSREGEGEG 454
EG L+ ++ G +LEG + + KP+ P G S G
Sbjct: 358 VPSANIEGLEGKLKGPQITGPSLEG---DLGLKGAKPQGHIGVDASAPQIGGSITGPSVE 414
Query: 455 LQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQR- 513
+Q+ +I + P ++ V +K PKF+ S K E ++ P
Sbjct: 415 VQAPDIDVQG---------------PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGE 459
Query: 514 ----GKRQDAS-SKAGTG-----LKGEEVE--------------------GAGWMPGREP 543
G D S + TG +KG +V+ G+ + G
Sbjct: 460 VTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIK 519
Query: 544 TTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGRE 603
+ QGD + L+ +R+ E + EG + P+ PS
Sbjct: 520 VSAPGVQGDVKGPQVALKGSRVDIETP----NLEGTLTGPRLGSPS-------------- 561
Query: 604 KATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQIL 663
G+ G + + +K D K+++ + R K +
Sbjct: 562 --------GKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVS 613
Query: 664 T-EKEVATKDSKFKMPKFKMPLF---GASAPGKSM-----EASVDVSAPKVEADVSLLSM 714
+ E + KMPK KMP F GA G + + + +S PKV + +++
Sbjct: 614 APDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNL 673
Query: 715 QG--------DLKTTDLSVQTPS-----ADLEVQD----GQVDVKLP--EGPLP------ 749
+G D+K D+SV+TP DL V+ G+ DV +P EG L
Sbjct: 674 EGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDI 733
Query: 750 -------EGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVD 802
G +PK++ P +P +GP++D+ PKA+V K+ +++ +V
Sbjct: 734 DAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVS 793
Query: 803 VQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPK 862
++ P KL G + + + K+PK MP + G +++ DV+ PK
Sbjct: 794 IEEPEGKLKGPKFK-----------MPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPK 842
Query: 863 VEA-----DVSLSSMQGDLKATDLSIQP-------------------------------P 886
VE+ DV L S + D+ D+ +Q P
Sbjct: 843 VESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP 902
Query: 887 SADLEVQAGQVDVKLP----EGPVPEGAGPKVHLPK--VEMPSFKMPKVDL--KGPQI-- 936
AD+++ +V V++P EGP + GPK +P+ ++ P MP VDL KGP++
Sbjct: 903 KADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKG 962
Query: 937 --DVKGPKL--DLKGPKAEVTAPDGEV-----------------SLPSM-----EVDVQA 970
D+ PKL DLKGPK +V+APD E+ S+PS+ E DV
Sbjct: 963 EYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNL 1022
Query: 971 QKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL-VDVSAPKVE 1029
KA +D + + D + D + + K K PKFKMP AP S+ + +D+ PK++
Sbjct: 1023 SKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMK 1082
Query: 1030 --ADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHL--PKVE 1085
D+S P ++G+++ D+ I + +VD+K P+ EG GL L PK++
Sbjct: 1083 GNVDISAPKIEGEMQVPDVDI---------RGPKVDIKAPD---VEGQGLDWSLKIPKMK 1130
Query: 1086 MPSFKMPKVALKGPQVDVKGPKLD--LKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSA 1143
MP F MP + +GP+VDV PK D + PK ++ APD V +E P KL
Sbjct: 1131 MPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPD---------VSLEGPEGKLKGP 1181
Query: 1144 RLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQ 1203
+ + + FK PK MP G ++ VDVS PKVE ++ +P ++
Sbjct: 1182 KFK-----------MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVE 1230
Query: 1204 -----GDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMP------ 1252
D+ D+ +Q P L++ ++ + G EG +LPK +
Sbjct: 1231 IKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKV 1290
Query: 1253 SLKMPKVDLKGPQVEVRGPK-------------------LDLKGHKAEVTAHEVAVSLPS 1293
+++P V L+GP+ +++GPK L+LKG K + +V VSLP
Sbjct: 1291 DVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLK---GDVDVSLPE 1347
Query: 1294 VEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEASVD 1352
VE +M+ P + G ++ D+S D DV D KMPK KMP F S PG K VD
Sbjct: 1348 VEGEMKVPDVDIKGPKV--DISAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVD 1403
Query: 1353 LSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDL---ELQAGQLDVKLPEGPVPE-GAGLK 1408
+ PK + D+S P M D + D++I+ P L + + ++ +K + +P+ G LK
Sbjct: 1404 VKLPKADVDVSGPKM--DAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLK 1461
Query: 1409 GHLPKLQMP-SFKVPKV--DLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSV------ 1459
G PK++ VPKV ++K P++DIKGPK+D+ P VEV PD + +P V
Sbjct: 1462 G--PKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFS 1519
Query: 1460 ---------EVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGK 1510
EVD+ P A L + D+ + D +L + K K PKFKMPS +
Sbjct: 1520 MPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKI 1579
Query: 1511 SI-EASVDVSAPKV--EADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPE---- 1563
S+ + +++ APK+ + DVSLP ++GDLK ++ ++ P D+ V G +D++ PE
Sbjct: 1580 SMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNV--GDIDIEGPEGKLK 1637
Query: 1564 GPVSEGAGLKGHLPKVQMPS----FKMPKV-------------DLKGPQIDVKGPKLDLK 1606
GP + + PK+ MP K PKV ++K P +D+KGPK+D+
Sbjct: 1638 GPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDID 1697
Query: 1607 GPKVEVTAPDVKMSLSSM---------------EVDVQAPRAKLDGAQLEGDLSLADKAV 1651
P VEV PD + + M EVDV P+A +D + D D +
Sbjct: 1698 APDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDI 1757
Query: 1652 TAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSEPKV--EADVSLPSMQGDLKTTDLSI 1708
+ K K KFKMP + AP S+ + +++ PK+ E D S+P ++GDL+ + +
Sbjct: 1758 EGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDV 1817
Query: 1709 QSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKV--ALKGPQM----D 1762
+ P + EV V+++ P+ L +G FK + P + MP V LKGP++ D
Sbjct: 1818 KGPFVEAEVP--DVDLECPDAKL-KGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDAD 1874
Query: 1763 VKGPKL--DLKGPKAEVMAPDVE------------------------VSLPSVEVDVEAP 1796
V PKL DL GP V PDVE +S+P V++ ++ P
Sbjct: 1875 VSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGP 1934
Query: 1797 GAKLD---SV-RLEGDLS-------LADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EA 1844
K D SV +LEGDL+ + D ++ D+K K PKFKMP P S+ +
Sbjct: 1935 KVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDV 1994
Query: 1845 SVDVSAPKV--EAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGL 1902
+ + PKV + +VS+P ++G++K D+ I P D + A VD+ P+ +
Sbjct: 1995 DLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMD--IDAPDVDVHGPDWHL------ 2046
Query: 1903 KGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLD--LKGPKAEVTAPDV------------- 1947
+PK+ MP F MP +GP+ DV K D + GPK +V PDV
Sbjct: 2047 --KMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPK 2104
Query: 1948 -----------EVSLPSMEVDVQAQKAKLDG----ARLEGDLS-------LADKDMTAKD 1985
++S+P +++ ++ K K D +LEGDL+ + D ++ D
Sbjct: 2105 LKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPD 2164
Query: 1986 SKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSMQGDLKTTDLSIQPPS 2042
+K K PKFKMP P S+ + ++++ PKV + DVS+P ++G++K D+ I+ P
Sbjct: 2165 AKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPK 2224
Query: 2043 ADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK--LDL 2100
D + VDV P+ H+ +PK++MP MP +GP+VD+ PK +D+
Sbjct: 2225 VD--IDAPDVDVHGPDWHL--------KMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDV 2274
Query: 2101 KDPKVEMRVPDV------------------------EVSLPSMEVDVQAPRAKLD----S 2132
PKV++ VPDV ++S+P ++ +++ P+ K D +
Sbjct: 2275 SGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSA 2334
Query: 2133 AHLQGDLTLANKD--------------LTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVD 2177
L+G+L D + + K+K PKFKMP AP S+ + +
Sbjct: 2335 PKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394
Query: 2178 VSPPKV--EADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQV------------------ 2217
+ PK E D+ +P ++GDLK + + D++ G++
Sbjct: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454
Query: 2218 --DVKL-LEGP---------VPE--------EVGLKG----------------------H 2235
DV L L+GP VPE ++ ++G
Sbjct: 2455 MPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMK 2514
Query: 2236 LPKLQMPSFKV------------------PKVDLKGPEIDIKGPKLDLKDPKVE-----V 2272
+PK MP FK PKVD++GP+++I+GP+ LK PK++ +
Sbjct: 2515 MPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNI 2574
Query: 2273 TAP------------------DVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAK 2314
AP DV+VSLP VE D+K P + G ++ D++ D V
Sbjct: 2575 KAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKV--DINAPDVGVQGP 2632
Query: 2315 DSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSAD 2374
D KMPK KM F + K DV K + DVS P + D++ D++++ P
Sbjct: 2633 DWHLKMPKVKMPKFSMPGF-KGEGPDGDVKLPKADIDVSGPKV--DIEGPDVNIEGPEGK 2689
Query: 2375 L---EVQAGQVDVKLPEGPVPE-GAGLKGHLPKLQMP-SFKMPKV--DLKGPQIDVKGPK 2427
L + + ++++K P+ +P+ LKG PK++ +PKV DLKGP++D+KGPK
Sbjct: 2690 LKGPKFKMPEMNIKAPKISMPDIDLNLKG--PKVKGDVDVSLPKVEGDLKGPEVDIKGPK 2747
Query: 2428 LDLKGPKTDVMAPDVEVSQPSV---------------EVDVEAPGAKLDGAWLEGDLSVA 2472
+D+ P DV PD + P + +VDV P A +D + + D+
Sbjct: 2748 VDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECP 2807
Query: 2473 DKDVTTKDSRFKIPKFKMPSFGVSAP------------GKSIEASVDVSAPKVEAD--GS 2518
D ++ + ++K PKFKMP P G I+ VDV+ PKVE D G
Sbjct: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGP 2867
Query: 2519 LSSMQG---DLKATDLSIQPPSADLEV---------------QAGQVDVKLPEGPVP--- 2557
++G D+ D+++Q P L++ + +VDV LP+ V
Sbjct: 2868 EVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSG 2927
Query: 2558 -----EG--AGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVTAPDVEMS 2610
EG ++G K++ P FKMPEM++K P++ + L LKGPK + DV++S
Sbjct: 2928 PKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVK---GDVDIS 2984
Query: 2611 LSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEAL 2670
L +E D++ P + G ++ D+ + D GV D KMPK KMP F S PG E
Sbjct: 2985 LPKVEGDLKGPEVDIRGPQV--DIDVPDVGVQGPDWHLKMPKVKMPKF--SMPGFKGEGP 3040
Query: 2671 -VDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQL---EVQAGQVDVKLPEGHVPE--- 2723
VDV+ K + D+S P + D+ D++I+ P +L + + ++++K P+ +P+
Sbjct: 3041 DVDVNLPKADLDVSGPKV--DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDL 3098
Query: 2724 ---GAGLKG----HLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSL 2776
G +KG LPK++ K+P+VD+KGP++D+ P+VD++GP + P +KM
Sbjct: 3099 NLKGPKVKGDMDVSLPKVE-GDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPK 3157
Query: 2777 SSM--------EVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAP 2828
SM EVDV P+A LD + + D+ + D + D+K K PKFKMP + AP
Sbjct: 3158 ISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAP 3217
Query: 2829 GKS---IEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDV------ 2879
S ++ ++ ++K E D S +++GDLK + I+ P +++V A +D+
Sbjct: 3218 KISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGP--KIDVDAPDIDIHGPDAK 3275
Query: 2880 ------KLPEGHV-------PE------GAGLKGHL----PKVQMPSFKMPKVDLKGPQI 2916
K+P+ HV PE G+ LKG + PK++ K P +D+KGP++
Sbjct: 3276 LKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLE-GDIKAPSLDIKGPEV 3334
Query: 2917 DVKGPKL-------------------------------------DLKGPKAEVTAPDVE- 2938
DV GPKL D+ GPK ++ APDVE
Sbjct: 3335 DVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEV 3394
Query: 2939 --------------------VSLPSVEVDVEAPRAKLD----GARLEGD----------- 2963
VS+P VE+++++P+ K D G LEGD
Sbjct: 3395 QGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAP 3454
Query: 2964 ---LSLADKDVTAKDSKFKMPKFKMPSFGVSA-PGKSIEVSVDVSAPKVEAEVSLPSMQG 3019
L+ D DV D KMPK KMP F VS + +V+VD+ PK + + PSM
Sbjct: 3455 EVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDL--PKGDINIEGPSM-- 3510
Query: 3020 DLKTTDISIEPPSAQL---EVQAGQVDLKLPEGHVPE------GAGLKG----HLPKLQM 3066
+++ D+++E P L + + +++K P+ +P+ G +KG LPKL+
Sbjct: 3511 NIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLE- 3569
Query: 3067 PSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEV---SQPGM-----EVDVEAPGA 3118
K P+VD KGP++D+ P +D+ GP + P V++ S PG EVDV P A
Sbjct: 3570 GDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKA 3629
Query: 3119 KLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVLVDVSAPKVEAD- 3176
+D + D+ + D ++ D+K K PKFKMP + AP S+ + +++ PK++ D
Sbjct: 3630 DIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDV 3689
Query: 3177 -LSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFK 3235
+SLP ++GDLK ++ I+ P ++++ ++++ EG +G K L+ P
Sbjct: 3690 VVSLPKVEGDLKGPEVDIKGP--KVDIDTPDINIEGSEGK-FKGPKFKIPEMHLKAPKIS 3746
Query: 3236 MPKVD--RKGPQI-------------DIKGPKLDLKGPKMDVTAPDVEVSQPSM------ 3274
MP +D KGP++ D+KGP++D+KGPK+D+ APDV+V P
Sbjct: 3747 MPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPK 3806
Query: 3275 ----------------EVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSY 3318
+VDV P A LD + + D+ + D ++ + K K PKFKMP
Sbjct: 3807 VKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEM 3866
Query: 3319 RASAPGKSI-QASVDVSAP--KAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVK 3375
AP S+ +++ P K + DVSLP ++GD++ DL I+ P VD + A VDV+
Sbjct: 3867 NIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD--INAPDVDVR 3924
Query: 3376 LPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPDVE 3433
P+ H+ +PK++MP MP + P+VD+ PK DL V PK +V VPD
Sbjct: 3925 GPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPD-- 3974
Query: 3434 VSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIE 3493
V+++ P AKL G + + + K PK MP F + G ++
Sbjct: 3975 -------VNIEGPDAKLKGPKFK-----------MPEMNIKAPKISMPDFDLHLKGPKVK 4016
Query: 3494 ASLDVSAPKVEAD-----VSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPE 3548
+DVS PK+E D V + + D+ A D+ + P L++ V++ + G E
Sbjct: 4017 GDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGE 4076
Query: 3549 GAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDV-----EVSLPS 3603
G + +LPK ++ + PKVD+ P ID+ GP+ LKGPK ++PD+ ++S+P
Sbjct: 4077 GPEVDVNLPKADI-DVSGPKVDIDTPDIDIHGPEGKLKGPK--FKMPDLHLKAPKISMPE 4133
Query: 3604 VEVDVQAPKAKLDA--------GRLEG----------DLSLADKDVTAKDSKFKMPKFKM 3645
V+++++ PK K D G L+G D+ + D DV D KMPK KM
Sbjct: 4134 VDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKM 4193
Query: 3646 PSFRVSAPG-KSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADL---KVQAGQ 3701
P F S PG K VDV+ PK + DVS P + D+ D++I+ P A L K + +
Sbjct: 4194 PKF--SMPGFKGEGPDVDVNLPKADLDVSGPKV--DIDVPDVNIEGPDAKLKGPKFKMPE 4249
Query: 3702 MDVKLPEGQVPEGAGLKEHL--PKVEMP-SLKMPKV--DLKGPQVDIKGPKLDLKVSKAE 3756
M++K P+ +P+ HL PKV+ + +PKV DLKGP+VDIKGPK+D+ +
Sbjct: 4250 MNIKAPKISMPD---FDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVD 4306
Query: 3757 VTAPDVEVSLPSV---------------EVDVQAPRAKLDSAQLEGDLSLADKDVTAKDS 3801
V PD + +P V +VDV P+A ++ + + D+ D + D+
Sbjct: 4307 VHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDA 4366
Query: 3802 KFKMPKFKMPSFGVSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSA 3858
K K PKFKMP + AP S+ + ++ PKV + DVSLP ++GDLK ++ I+ S
Sbjct: 4367 KLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSL 4426
Query: 3859 DL-----TVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSF----KMPKV---------- 3899
D+ ++ + +K + +PE + PK+ MP F K PKV
Sbjct: 4427 DIDTPDVNIEGPEGKLKGPKFKMPE---MNIKAPKISMPDFDLHLKGPKVKGDVDVSLPK 4483
Query: 3900 ---DLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSV---EVDVEAPGAKLDG------ 3947
DLKGPE+DI+GP+ LK PK ++ PDV P + ++D+ G K+ G
Sbjct: 4484 VESDLKGPEVDIEGPEGKLKGPKFKM--PDVHFKSPQISMSDIDLNLKGPKIKGDMDISV 4541
Query: 3948 ARLEGDL--------------SLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSM-EASVD 3992
+LEGDL D D+ + K K PKFKMP + AP SM E ++
Sbjct: 4542 PKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLN 4601
Query: 3993 VTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGH 4050
+ PKV + D+SLP ++GDLK ++ ++ P D++V VDV+ P+ +
Sbjct: 4602 LKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVP--DVDVQGPDWHL--------K 4651
Query: 4051 LPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDVKMSLSSMEVDVQAPRA 4108
+PKV+MP F MP +GP +DV PK +D+ GPK +V PD V+++ P A
Sbjct: 4652 MPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPD---------VNIEGPDA 4702
Query: 4109 KLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSM---EASVDVSELKAKA 4165
KL G PKFKMP + AP SM + ++ ++K
Sbjct: 4703 KLKG-----------------------PKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDV 4739
Query: 4166 DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLK 4225
DV+LP ++GDLK + I+ P D + VDV P+ L +PKV+MP
Sbjct: 4740 DVTLPKVEGDLKGPEADIKGPKVD--INTPDVDVHGPDWHL--------KMPKVKMPKFS 4789
Query: 4226 MPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLS 4285
MP +GP VDV PK D+ DV P V+V +P +V++E P
Sbjct: 4790 MPGFKGEGPDVDVSLPKADI-----DVSGPKVDVDIP--DVNIEGP-------------- 4828
Query: 4286 LADKDMTAKDSKFKMPKFKMPSFGVSAPGKSI-EASLDVSALKVEA--DVSLPSMQGDLK 4342
D+K K PKFKMP + AP SI + LD+ KV+ DVS+P ++G LK
Sbjct: 4829 ---------DAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLK 4879
Query: 4343 TTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPS----FKVPKVDLKG 4398
+ ++ P D E D KL GP + L+ PK+ P K PK+ G
Sbjct: 4880 GPEVDLKGPRLDFE----GPDAKL-SGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSG 4934
Query: 4399 PQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAK------------------- 4439
P+++ ++DLKGPKVE +P+LDV + S +++I+ P K
Sbjct: 4935 PKLEGG--EVDLKGPKVE--APSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKAD 4990
Query: 4440 -----LDSTRLEGDLSLADKDVT----AKDSKFKMPKF---------KMPSFGMLSPGKS 4481
LD T E +L+L +++ K SKFKMPK K F + PG
Sbjct: 4991 IKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGE 5050
Query: 4482 IEVS------------------VDVSAPK----MEADMSIPSMQGDLKTTDLRIQA---- 4515
I+ S VDV +PK M M P ++ D+K+ + +A
Sbjct: 5051 IDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPS 5110
Query: 4516 PSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMP--SFKMPKV--DLKGP--QVDVK 4569
P + E+QA ++L LP H+ E +K PKV+MP +PK+ DLKGP Q ++
Sbjct: 5111 PKLEGELQAPDLELSLPAIHV-EGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLG 5169
Query: 4570 GPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQ 4629
P ++++G A+V P +S P V + L G +++GD+ + G D Q
Sbjct: 5170 APDINIEGLDAKVKTPSFGISAPQV--SIPDVNVNLKGPKIKGDVPSV--GLEGPDVDLQ 5225
Query: 4630 GPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLA 4689
GP+ ++S K+ + ++EG E + P + EGDL P
Sbjct: 5226 GPEAKIKFPKFSMPKIGIPGVKMEGGGA--EVHAQLPSL-----EGDLRGPD-------- 5270
Query: 4690 VGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSL-----VPGAKSSIGLSTIPLSSSECSSF 4744
V G D K +P V+ S K L P K + S +P
Sbjct: 5271 VKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDAS-VPSMKVHAPGL 5329
Query: 4745 ELQQVSACSE--------PSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQ 4796
L V + P + G P + L GP + L+ D+ K
Sbjct: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPD--VTLRGPSLQGD-LAVSGDIKCPKVS 5386
Query: 4797 VTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVS 4856
V AP+L+LE GS I LPK + P G+ T ++ H +
Sbjct: 5387 VG------APDLSLEASEGS---IKLPKMKL-----PQFGISTPGSDLHVNAKGPQVSGE 5432
Query: 4857 LG------QVSFPKFYKPKFVFSVPQMAVPEGDLHAA--VGAPVMSPLSPGERVQCPLPS 4908
L + P+ P F++ V +G L A + P + PG VQ +
Sbjct: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKV-KGSLGATGEIKGPTVGGGLPGIGVQGLEGN 5491
Query: 4909 TQLPS----------PGTCVS------QGPEELVASLQTSVVAPGEAPSEDADHEGKGSP 4952
Q+P PG V GPE + V G AP D +G
Sbjct: 5492 LQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAP--DISVKGPAFN 5549
Query: 4953 LKMPKIKLPSFRWSPKKETGPKVD-----PECSVEDSKLSL--------------VLDKD 4993
+ P+ PK + G V P+ S+ + LS+ L+ D
Sbjct: 5550 MASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLD 5609
Query: 4994 EVAPQSAIHMDLPPERDGEKGRS---TKPGFAMP-----------KLALPKMKASK---S 5036
+H P G KG PG ++ K+ PKMK K S
Sbjct: 5610 TSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFS 5669
Query: 5037 GVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPS 5096
G L R++ + A S Q GA V L + ++ +P
Sbjct: 5670 GRELVGREMGVDVHFPKAEASIQ-------------AGAGDGEWEESEVKLKKSKIKMPK 5716
Query: 5097 LGFAKPDLRSSKAKVEVS-QPEADLPLPKHDLSTEGDSRGC--GLGDVPVSQPCGEGIAP 5153
F+KP K K V+ PEA + K DL + S G G + S P G+
Sbjct: 5717 FNFSKP-----KGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLF 5771
Query: 5154 TPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAG-- 5211
+ P S D + S + E + K + + F GG G
Sbjct: 5772 KSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSK 5831
Query: 5212 -KLEVAQTQAPAATG-----GEAAAKVKEFLVSGSNVEAA--MSLQLPEADAEVTASE 5261
K T + TG G + A K L S S+ ++ + +QLPE + V+ +
Sbjct: 5832 SKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKK 5889
Score = 510 bits (1313), Expect = e-143
Identities = 601/2369 (25%), Positives = 995/2369 (42%), Gaps = 520/2369 (21%)
Query: 3330 SVDVSAPKAEADVSLPSMQGDLKTTDLSI-QLPSVDLEVQAGQVDVKLPEGH---VPEGA 3385
+VDV+ + D+ + S + +K + ++ +VD+E Q+G+ ++LP G P G+
Sbjct: 161 TVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGS 220
Query: 3386 GLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLD-LKVPKAEVTVPDVEVSLPSVEVD-- 3442
VD+++ + GP+L K +VT+P ++V V V+
Sbjct: 221 A-----------------VDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAK 263
Query: 3443 ---------VQAPRAKLDGARLEGDLSLAEKDVTAKD-SKFKMPKFKMPSFGVSA--PGR 3490
VQ P + + + + + + D K K P K+P FGVS G+
Sbjct: 264 GLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQ 323
Query: 3491 SIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEG- 3549
+ +A L VSAP+V ++A L + PSA++E ++ + GP EG
Sbjct: 324 TPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGD 383
Query: 3550 AGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQ 3609
GLKG P+ + VD PQI + GP EV+ PD+ DVQ
Sbjct: 384 LGLKGAKPQGHIG------VDASAPQIGGS-----ITGPSVEVQAPDI---------DVQ 423
Query: 3610 APKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVE 3669
P SK +PK K+P F VS K E +DV+ P E
Sbjct: 424 GP-----------------------GSKLNVPKMKVPKFSVSG-AKGEETGIDVTLPTGE 459
Query: 3670 ADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSL 3729
V++P + GD+ +++ G ++ K+ +G +K ++ P +
Sbjct: 460 --VTVPGVSGDVSLPEIA-----------TGGLEGKM------KGTKVKTPEMIIQKPKI 500
Query: 3730 KMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDL 3789
M VDL +KG D++VS P V+ DV+ P+ L +++ D+
Sbjct: 501 SMQDVDLSLGSPKLKG---------------DIKVSAPGVQGDVKGPQVALKGSRV--DI 543
Query: 3790 SLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEA--DVSLPSMQGDLK 3847
+ + T + P K + +S E ++V+APKV+ DV+LP ++G +K
Sbjct: 544 ETPNLEGTLTGPRLGSPSGKTGTCRISMS----EVDLNVAAPKVKGGVDVTLPRVEGKVK 599
Query: 3848 TTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEID 3907
++ ++ D++ +E H PE LK +PK++MP+F P +GP++
Sbjct: 600 VPEVDVRGPKVDVSAPD-------VEAHGPEW-NLK--MPKMKMPTFSTPGAKGEGPDVH 649
Query: 3908 IKGPKLDLK--DPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKD 3965
+ PK D+ PKV V APDV ++E G KL G D+ D
Sbjct: 650 MTLPKGDISISGPKVNVEAPDV---------NLEGLGGKLKGP-----------DVKLPD 689
Query: 3966 SKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADL 4025
K PK MP + G ++ DVT PK+E ++ P + D+ A D+ V P L
Sbjct: 690 MSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKV--DIDAPDVDVHGPDWHL 747
Query: 4026 EVQAGQVDVKLPEGPVP----EGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK 4081
++ +K+P+ VP EG + +LPK + PK+D+ P + ++ P+ LK
Sbjct: 748 KMPK----MKMPKFSVPGFKAEGPEVDVNLPKADV-DISGPKIDVTAPDVSIEEPEGKLK 802
Query: 4082 GPK----------AEVTAPDVKMSLSSMEV----DVQAPRA----KLDGVQLEG---DLS 4120
GPK +++ PDV + L V DV P+ K+ V+L+ D+
Sbjct: 803 GPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDID 862
Query: 4121 LADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEA-SVDVSELKAKADVSLPSMQGDLKTT 4179
+ D +V D KMPK KMP F S PG E VDV+ KA D+S P + ++
Sbjct: 863 VPDVEVQGPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADVDISGPKV--GVEVP 918
Query: 4180 DLSIQSPSADLE---VQAGQVDVKLPEGPLP------KGAGLKGHLPKVQMPCLKMPKVA 4230
D++I+ P L+ + ++++K P+ +P KG +KG + +PK+
Sbjct: 919 DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYD------MTVPKLE 972
Query: 4231 --LKGPQVDVKGPKLDLKGPKADVMTPVVEV---SLPSM-----EVDVEAPGAKLDSVRL 4280
LKGP+VDV P ++++GP ++ P +++ S+PS+ E DV A +D
Sbjct: 973 GDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAP 1032
Query: 4281 EGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSI-EASLDVSALKVEA--DVSLPSM 4337
+ D + D + + K K PKFKMP AP S+ + LD+ K++ D+S P +
Sbjct: 1033 KVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKI 1092
Query: 4338 QGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHL--PKLQMPSFKVPKVD 4395
+G+++ + I+ P D++ P EG GL L PK++MP F +P +
Sbjct: 1093 EGEMQVPDVDIRGPKVDIKA------------PDVEGQGLDWSLKIPKMKMPKFSMPSLK 1140
Query: 4396 LKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKD 4455
+GP++DVN+PK D V V+ P +D+ P +V ++ P KL + +
Sbjct: 1141 GEGPEVDVNLPKAD-----VVVSGPKVDIEAP--DVSLEGPEGKLKGPKFK--------- 1184
Query: 4456 VTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQA 4515
+ FK PK MP + G ++ VDVS PK+E +M +P ++ +K + I A
Sbjct: 1185 --MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVE--IKGPKMDIDA 1240
Query: 4516 PSADLEVQAGQVDLKLPEGHMPEVA--GLKG-------HLPKVEM--------------- 4551
P D+EVQ LK+P+ MP+ + G KG +LPK ++
Sbjct: 1241 P--DVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVS 1298
Query: 4552 ----------PSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAP 4601
P FKMP++ K P++ + L+LKGPK + DV+VSLP VE +++ P
Sbjct: 1299 LEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPK---LKGDVDVSLPEVEGEMKVP 1355
Query: 4602 GSMLDGARLEGDLSLAHEDVAGKD-----SKFQGPKLSTSGFEWSSKKVSMSSSEIEGNV 4656
+ G ++ D+S DV G D K + PK S GF+ +V + + + +V
Sbjct: 1356 DVDIKGPKV--DISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDV 1413
Query: 4657 TFHEKTSTFPIVESVVHEGDLHDPSRD------GNLGLAVGEVGMDSKFKKLH----FKV 4706
+ + + P V + L P +++ +VG+ K K+ V
Sbjct: 1414 SGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTV 1473
Query: 4707 PKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAG 4766
PKV K P D + G K I + + + + L+ P ++MPK G
Sbjct: 1474 PKVE-GEIKAP-DVDIKGPKVDINAPDVEVHGPD---WHLKM------PKVKMPKFSMPG 1522
Query: 4767 FPSS--RLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALA------------------P 4806
F +D+ P + + P D+ + + P L P
Sbjct: 1523 FKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMP 1582
Query: 4807 ELALEIPSG---SQADIPLPKTECSTDLQPPE-GVPTSQAESHSGPLNSMIPVSLGQVSF 4862
++ L + + + D+ LPK E DL+ PE V + + + G ++ P G++
Sbjct: 1583 DVGLNLKAPKLKTDVDVSLPKVE--GDLKGPEIDVKAPKMDVNVGDIDIEGPE--GKLKG 1638
Query: 4863 PKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGER-VQCPLPSTQLPSPGTCVSQG 4921
PKF P+ F P++++P+ DLH + P G+ V P ++ P + +G
Sbjct: 1639 PKFKMPEMHFKAPKISMPDVDLH------LKGPKVKGDMDVSVPKVEGEMKVPDVDI-KG 1691
Query: 4922 PEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVD---PE 4978
P+ + AP D + LKMPK+K+P F K GP+VD P+
Sbjct: 1692 PK-------VDIDAP------DVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPK 1738
Query: 4979 CSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGV 5038
++ S S+ D ++ + +G +G+ F MPKL +KA K V
Sbjct: 1739 ADIDVSGPSVDTDAPDL------------DIEGPEGKLKGSKFKMPKL---NIKAPK--V 1781
Query: 5039 SLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEG----VNLHRPQVHI 5094
S+P DVD +L G D +G G E V+L P +
Sbjct: 1782 SMP--DVDLNLKGPKLKGEI-DASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKL 1838
Query: 5095 PSLGFAKPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPT 5154
F P++ K+ S P+ DL L + GD VS P EG
Sbjct: 1839 KGPKFKMPEMHFKAPKI--SMPDVDLHLKGPKVK----------GDADVSVPKLEGDLTG 1886
Query: 5155 PEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLE 5214
P ++ PD E+ E P+ + K PKF+MP +
Sbjct: 1887 PSVGVEV----PDVEL---ECPDAK----------LKGPKFKMPDMHFK----------- 1918
Query: 5215 VAQTQAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDIL--RCD 5272
A + +P+ D + + K D+ + +
Sbjct: 1919 ------------------------------APKISMPDVDLHLKGPKVKGDVDVSVPKLE 1948
Query: 5273 LDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEID---ETP 5329
D TG + + + EL + ++ KGP F+MP M ++ ++D + P
Sbjct: 1949 GDLTGPSVGVEVPDV---ELECPDAKL---KGP-KFKMPEMHFKTPKISMPDVDLHLKGP 2001
Query: 5330 LSKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKL 5389
K D++ K E P+ +K D P + V D W +K PK+
Sbjct: 2002 KVKGDMDVSV--PKVEGEMKVPDVDIKGPKMDIDAPD-VDVHGPD--WH-----LKMPKM 2051
Query: 5390 MVPRFSFPAPSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQP- 5448
+P+FS P +E PE +++ L A ++ +G V E P
Sbjct: 2052 KMPKFSMPGFKAEG------------PEVDVN---------LPKADVVVSGPKVDVEVPD 2090
Query: 5449 VDLNLP---LEAPPISKVRVHIQGAQVESQEVTIHSIVTPEF---VDLSVPRTFS--TQI 5500
V L P L+ P + +H + ++ +V +H + P+ VD+S+P+ T
Sbjct: 2091 VSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLH-LKGPKVKGDVDVSLPKLEGDLTGP 2149
Query: 5501 VRESEIPTSEIQTPSYGFSLLKVKIPEPH 5529
+ E+P E++ P K K+PE H
Sbjct: 2150 SVDVEVPDVELECPDAKLKGPKFKMPEMH 2178
Score = 427 bits (1098), Expect = e-118
Identities = 547/2249 (24%), Positives = 907/2249 (40%), Gaps = 485/2249 (21%)
Query: 3479 KMPSFGVSAPGRSIEASLDVSAPKVEADV------SLSSMQGDLKATDLSIQPPSADLEV 3532
++ ++ V GR +D+S+P+ + + +S++ + ++ I+ PS
Sbjct: 156 RVTAYTVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAA 215
Query: 3533 QAVQVDVELLEGPV----PEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGP 3588
V++ G + PE G +V MP +K + G ++V LDL G
Sbjct: 216 SPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIK-----VGGSGVNVNAKGLDLGG- 269
Query: 3589 KAEVRVPDVEVS--LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMP 3646
+ V+VP V++S L V+VQ P + GD K K P K+P
Sbjct: 270 RGGVQVPAVDISSSLGGRAVEVQGPSLE------SGD-----------HGKIKFPTMKVP 312
Query: 3647 SFRVSA--PGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDV 3704
F VS G++ +A + VSAP+V + + L +QA Q++V
Sbjct: 313 KFGVSTGREGQTPKAGLRVSAPEVS----------------VGHKGGKPGLTIQAPQLEV 356
Query: 3705 KLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEV 3764
+P + EG K P++ PSL+ + +KG K + + +AP +
Sbjct: 357 SVPSANI-EGLEGKLKGPQITGPSLE--------GDLGLKGAKPQGHIG-VDASAPQIGG 406
Query: 3765 SLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEA 3824
S+ V+VQAP D DV SK +PK K+P F VS K E
Sbjct: 407 SITGPSVEVQAP----------------DIDVQGPGSKLNVPKMKVPKFSVSG-AKGEET 449
Query: 3825 SVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKG 3884
+ V+ P E V++P + GD+ +++ GL+G
Sbjct: 450 GIDVTLPTGE--VTVPGVSGDVSLPEIAT--------------------------GGLEG 481
Query: 3885 HLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAP----DVEVSLPSVEVDVEA 3940
KM +K PE+ I+ PK+ ++D + + +P D++VS P V+ DV+
Sbjct: 482 ----------KMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKG 531
Query: 3941 PGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEA 4000
P L G+R+ D+ + + T + P K + +S E ++V APKV+
Sbjct: 532 PQVALKGSRV--DIETPNLEGTLTGPRLGSPSGKTGTCRISMS----EVDLNVAAPKVKG 585
Query: 4001 --DVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPS 4058
DV+LP ++G +K ++ V+ P D V A V+ PE +LK +PK++MP+
Sbjct: 586 GVDVTLPRVEGKVKVPEVDVRGPKVD--VSAPDVEAHGPEW------NLK--MPKMKMPT 635
Query: 4059 FKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGD 4118
F P +GP + + PK D+ S+S +V+V+AP L+G L G
Sbjct: 636 FSTPGAKGEGPDVHMTLPKGDI--------------SISGPKVNVEAPDVNLEG--LGGK 679
Query: 4119 LSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKT 4178
L DV D K PK MP + G +++K + DV++P ++G+LK
Sbjct: 680 LK--GPDVKLPDMSVKTPKISMPDVDLHVKG---------TKVKGEYDVTVPKLEGELKG 728
Query: 4179 TDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDV 4238
+ I +P VDV P+ L +PK++MP +P +GP+VDV
Sbjct: 729 PKVDIDAPD---------VDVHGPDWHLK--------MPKMKMPKFSVPGFKAEGPEVDV 771
Query: 4239 KGPK--LDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDS 4296
PK +D+ GPK DV P +V +E P KL + + +
Sbjct: 772 NLPKADVDISGPKIDVTAP---------DVSIEEPEGKLKGPKFK-----------MPEM 811
Query: 4297 KFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLE 4356
K+PK MP + G +++ DV+ KVE+++ +P ++ LK+ + I P D+E
Sbjct: 812 NIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVE--LKSAKMDIDVP--DVE 867
Query: 4357 VQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVE 4416
VQ +K+P K++MP F +P +GP++DVN+PK D V+
Sbjct: 868 VQGPDWHLKMP---------------KMKMPKFSMPGFKAEGPEVDVNLPKAD-----VD 907
Query: 4417 VTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGML 4476
++ P + V +P +V+I+ P KL K PKFKMP +
Sbjct: 908 ISGPKVGVEVP--DVNIEGPEGKL-----------------------KGPKFKMPEMNIK 942
Query: 4477 SPGKSI-EVSVDVSAPKM--EADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPE 4533
+P S+ +V + + PK+ E DM++P ++GDLK + + AP D+E+Q +LK+P+
Sbjct: 943 APKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAP--DVEMQGPDWNLKMPK 1000
Query: 4534 GHMPEVA--GLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEV-- 4589
MP+ + LKG P+ ++ + VD+ P+VD P L L+GP+ ++ P ++
Sbjct: 1001 IKMPKFSMPSLKGEGPEFDV-NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPE 1059
Query: 4590 --------SLPSVETDVQAP---GSM-LDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSG 4637
SLP V+ D++ P G++ + ++EG++ + D+ G + P + G
Sbjct: 1060 MHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQG 1119
Query: 4638 FEWSSK-------KVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAV 4690
+WS K K SM S + EG E P + VV + + D +L
Sbjct: 1120 LDWSLKIPKMKMPKFSMPSLKGEGP----EVDVNLPKADVVVSGPKVDIEAPDVSLEGPE 1175
Query: 4691 GEV-GMDSKFKKLHFKVPKVSFSST----KTPK-----DSLVPGAKSSIGLSTI----PL 4736
G++ G K ++HFK PK+S K PK D VP + + + + P
Sbjct: 1176 GKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPK 1235
Query: 4737 SSSECSSFELQQVS-ACSEPSMQMPKVGFAGFPSS--RLDLTGPHFESSILSPCEDVTLT 4793
+ E+Q P M+MPK GF +D+ P + + P DV +
Sbjct: 1236 MDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVP 1295
Query: 4794 KYQVTVPRAALA------PELALEIPSGSQADIPL----PKTECSTDLQPPE-------- 4835
+ P L PE+ + P S D+ L PK + D+ PE
Sbjct: 1296 DVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVP 1355
Query: 4836 ---------GVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHA 4886
+ + H + +P +V PKF P F P++ V
Sbjct: 1356 DVDIKGPKVDISAPDVDVHGPDWHLKMP----KVKMPKFSMPGFKGEGPEVDVKLPKADV 1411
Query: 4887 AVGAPVMSPLSPGERVQCP----------------------LPSTQLPSPGTCVSQGPEE 4924
V P M P ++ P +P L G + +
Sbjct: 1412 DVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDV 1471
Query: 4925 LVASLQTSVVAPG--------EAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVD 4976
V ++ + AP + + D + G LKMPK+K+P F K GP+VD
Sbjct: 1472 TVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVD 1531
Query: 4977 PECSVEDSKLSLVLDKDEVAPQSAIHMDLPPER-DGEKGRSTKPGFAMPKLALPKMKASK 5035
D +S P+ + +D+P + +G+ P F MP + + K S
Sbjct: 1532 MNLPKADLGVS--------GPK--VDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISM 1581
Query: 5036 SGVSLPQR------DVDPSLSSATAG--GSFQDTEKASSDGGRGGLGATASATGSEGVNL 5087
V L + DVD SL G D + D G + +G
Sbjct: 1582 PDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKF 1641
Query: 5088 HRPQVHIPSLGFAKPD----LRSSKAK--VEVSQPEADLPLPKHDLSTEGDSRGCGLGDV 5141
P++H + + PD L+ K K ++VS P+ + + D+ +G DV
Sbjct: 1642 KMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDV 1701
Query: 5142 PVSQPCGEGIAPTPEDP-------------LQPSCRKPDAEV-----------LTVESPE 5177
V P P + P + + K D +V L +E PE
Sbjct: 1702 EVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPE 1761
Query: 5178 EEAMTKYSQESWFKMPKFRMPSLRRSFRD-----RGGAGKLEVAQTQAPAATGGEAAAKV 5232
+ + S FKMPK + + + S D +G K E+ P G +V
Sbjct: 1762 GKL-----KGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEI-DASVPELEGDLRGPQV 1815
Query: 5233 KEFLVSGSNVEAAMSLQLPEADAEVTASESKS------STDILRCDLDSTGLKLHLSTAG 5286
V G VEA ++P+ D E ++ K + + LHL
Sbjct: 1816 D---VKGPFVEA----EVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPK 1868
Query: 5287 MTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEK 5346
+ GD ++V + +G L G+ +P+ ++ E + L P + M K K
Sbjct: 1869 VKGD----ADVSVPKLEGDLTGPSVGVEVPDVEL---ECPDAKLKGPKFKMPDMHFKAPK 1921
Query: 5347 WSSQPEGPLKLKASSTDMPSQISVVNVD-QLWEDSV-------------LTVKFPKLMVP 5392
S P+ L LK +SV ++ L SV +K PK +P
Sbjct: 1922 -ISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP 1980
Query: 5393 RFSFPAPS-SEDDVFI----PTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQ 5447
F P S DV + P V+ ++D ++ K + + G + +
Sbjct: 1981 EMHFKTPKISMPDVDLHLKGPKVK------GDMDVSVPKVEGEMKVPDVDIKGPKMDIDA 2034
Query: 5448 P-VDLNLP---LEAPPISKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRE 5503
P VD++ P L+ P + + + G + E EV ++ + V +S P+ +
Sbjct: 2035 PDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN--LPKADVVVSGPKV-------D 2085
Query: 5504 SEIPTSEIQTPSYGFSLLKVKIPEPHTQA 5532
E+P ++ P K+K+PE H +A
Sbjct: 2086 VEVPDVSLEGPEGKLKGPKLKMPEMHFKA 2114
Score = 46.2 bits (108), Expect = 0.001
Identities = 107/507 (21%), Positives = 187/507 (36%), Gaps = 83/507 (16%)
Query: 5065 SSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKVEVSQPEADLPLPK 5124
S DG G LG T S T + + V + R +++S PE + +P+
Sbjct: 135 SEDGVEGDLGETQSRTITVTRRVTAYTVDVTG--------REGAKDIDISSPEFKIKIPR 186
Query: 5125 HDLSTEGDSRGCGLGDVPVSQPCGEGI--APTPEDPLQPSCRKPDAEVLTVESPEEEAMT 5182
H+L+ + +V V G+ + P+ P+ D + + E
Sbjct: 187 HELTE--------ISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQG 238
Query: 5183 KYSQESWFKMPKFRM----PSLRRSFRDRGGAGKLEVAQTQAPAATGGEAAAKVKEFLVS 5238
+ MP ++ ++ D GG G ++V ++ GG A L S
Sbjct: 239 AGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLES 298
Query: 5239 GSNVEAAM-SLQLPEADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEV 5297
G + + ++++P+ STG + AG+ +S EV
Sbjct: 299 GDHGKIKFPTMKVPKFGV-------------------STGREGQTPKAGL---RVSAPEV 336
Query: 5298 RIHPSKGP--LPFQMPGMRLPETQVLPGEID--ETPLSKPGHDLASMEDKTEKWSSQPEG 5353
+ G L Q P + E V I+ E L P S+E ++P+G
Sbjct: 337 SVGHKGGKPGLTIQAPQL---EVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQG 393
Query: 5354 PLKLKASSTDM------PS-QISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSED--- 5403
+ + AS+ + PS ++ ++D S L V PK+ VP+FS E+
Sbjct: 394 HIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNV--PKMKVPKFSVSGAKGEETGI 451
Query: 5404 DVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPV---------DLNLP 5454
DV +PT EV P + D +L + + G G G V + + D++L
Sbjct: 452 DVTLPT-GEVTVPGVSGDVSLPEIATG--GLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508
Query: 5455 LEAPPI-SKVRVHIQGAQ--VESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEI 5511
L +P + ++V G Q V+ +V + VD+ P T P+ +
Sbjct: 509 LGSPKLKGDIKVSAPGVQGDVKGPQVALKG----SRVDIETPNLEGTLTGPRLGSPSGKT 564
Query: 5512 QTPSYGFSLLKVKIPEPHTQARVYTTM 5538
T S + + + P + V T+
Sbjct: 565 GTCRISMSEVDLNVAAPKVKGGVDVTL 591
>gi|116686120 periaxin isoform 2 [Homo sapiens]
Length = 1461
Score = 216 bits (549), Expect = 7e-55
Identities = 364/1487 (24%), Positives = 628/1487 (42%), Gaps = 300/1487 (20%)
Query: 1432 DIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDS 1491
+IKGP+ + ++ +P + + + V A A +D S + L +
Sbjct: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
Query: 1492 KFKMP------KFKMPSFGVSAPGKSIEAS-VDVSAP-----KVEADVSLPSMQGDLKAT 1539
K +P + ++P V + +A+ + +AP KVEA+V+ + +
Sbjct: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235
Query: 1540 DLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQM-----PSFKMPKVDLKGP 1594
+ + P A++ V P + G L HLP + + P+ + P V ++ P
Sbjct: 236 LVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFAL--HLPTLGLGAPAPPAVEAPAVGIQVP 293
Query: 1595 QIDVKG----------PKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDL 1644
Q+++ P L+ + V V P + ++ ++ VD+ P A+++ ++
Sbjct: 294 QVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEV 353
Query: 1645 SLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTT 1704
+L KMP+ P FG A K + A V++ EA V P ++ + T
Sbjct: 354 AL------------KMPRLSFPRFGARA--KEV-AEAKVAKVSPEARVKGPRLR--MPTF 396
Query: 1705 DLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDV- 1763
LS+ P PE K LP ++MPSL + + GP++ V
Sbjct: 397 GLSLLEPRP----------------AAPEVVESKLKLPTIKMPSLG---IGVSGPEVKVP 437
Query: 1764 KGPKLDLKGPKA-EVMAPDV-EVSLPSVEV-DVEAPGAKLDSVRLEGDLSLADKDVTA-- 1818
KGP++ L PKA EV P V E +LP V + +VE P K+ ++L +A +V
Sbjct: 438 KGPEVKL--PKAPEVKLPKVPEAALPEVRLPEVELP--KVSEMKLPKVPEMAVPEVRLPE 493
Query: 1819 ----KDSKFKMPKF-KMPSFGVSAPGKSIEASVDVSAPKVEA----EVSLPSMQGDLKTT 1869
K S+ K+PK +M V P + ++ PKV EV LP +Q K +
Sbjct: 494 VELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLP-KVS 552
Query: 1870 DLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKV-DLKGPQTDV 1928
++ +P S + +++LPE Q+P+ +P++ +P K+PKV ++K P+ +
Sbjct: 553 EMKLPEVS-----EVAVPEVRLPEVQLPK-------VPEMKVPEMKLPKVPEMKLPEMKL 600
Query: 1929 KGAKLDLKGPKA-EVTAPDV---EVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAK 1984
+L PK E+ PDV EV LP + +++ + KL +L +A D+
Sbjct: 601 PEVQL----PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKLPKVPEMAVPDVHLP 655
Query: 1985 DSKF-KMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSA 2043
+ + K+P+ K+P A VP +V LP +Q K +++ + P
Sbjct: 656 EVQLPKVPEMKLPKMPEMA----------VP------EVRLPEVQLP-KVSEMKL-PKVP 697
Query: 2044 DLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKV-DLKGPQVDIKGPKLDLKD 2102
++ V DV LPE +P+ +K +P +++P +K+PKV ++ P V + P++ L
Sbjct: 698 EMAVP----DVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVPDVHL--PEVQL-- 747
Query: 2103 PKV-EMRVPDVEV-SLPSMEVDVQAPRAKLDSA-HLQGDLTLANKDLTTKDSKFKMPKFK 2159
PKV E+R+P+++V +P + + +AP KL A +Q T A + + FKMPK
Sbjct: 748 PKVSEIRLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKATKAEQ-AEGMEFGFKMPKMT 805
Query: 2160 MPSFGVS---APGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQ 2216
MP G + + GK EA +VS V +LP +Q ++ + V
Sbjct: 806 MPKLGRAESPSRGKPGEAGAEVSGKLV----TLPCLQPEV----------DGEAHVGVPS 851
Query: 2217 VDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVD-LKGPEIDIKGPKLDLKDPKVEVTAP 2275
+ + +E +P +GL+G Q+P+ K+ K + ++GPE+ ++ + P VE+ P
Sbjct: 852 LTLPSVELDLPGALGLQG-----QVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTP 906
Query: 2276 DVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGK 2335
LP+VE++ EG + + + V SKF +PKF + G
Sbjct: 907 Q----LPAVEIE-------------EGRLEMIETKVKPS-SKFSLPKFGLS--GPKVAKA 946
Query: 2336 SIEASADVSALKVEA-DVSLPSM----QGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGP 2390
E + + LKV +SLP + + K + P+ DL + +D LP G
Sbjct: 947 EAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSG- 1005
Query: 2391 VPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVE 2450
KV++ G + KGP+ L PK V D E ++
Sbjct: 1006 ----------------------KVEVAGADLKFKGPRFAL--PKFGVRGRDTEAAEL--- 1038
Query: 2451 VDVEAPG-AKLDG---AWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASV 2506
PG A+L+G W D R K+PK KMPSFG+ A GK E
Sbjct: 1039 ----VPGVAELEGKGWGW---------------DGRVKMPKLKMPSFGL-ARGKEAEVQG 1078
Query: 2507 DVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKG-- 2564
D ++P +A+ +T + ++ P +L Q + + G L G
Sbjct: 1079 DRASPGEKAE-----------STAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLK 1127
Query: 2565 ------HLPKVQMPSFKMPEMDLKGPQLDVKG-PKLDLKGPKAEVTAPDVEMSLSSMEVD 2617
+ + +MP + + PQ+++ G + G +A+ T P E + V
Sbjct: 1128 VSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAE-GTAGYRVQ 1186
Query: 2618 VQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFR----VSAPGESIEALVDV 2673
V L GA++ G L +GV FKMP +P +S ++ EA
Sbjct: 1187 VPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQLELDVGLSREAQAGEAATGE 1240
Query: 2674 SELKVEADMSLPSMQGDLKT--TDISIQPPSAQLEVQAGQVDVKL-PEG------HVPEG 2724
L+ + LP++ + QPP A+ DV+L P G V EG
Sbjct: 1241 GGLR----LKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG 1296
Query: 2725 AGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQ 2784
G GH K+++P F + +G K ++ P V S S M
Sbjct: 1297 EGEAGHKLKVRLPRFGLVRAK--------EGAEEGEKAKSPKLRLPRVGFSQSEMVTGEG 1348
Query: 2785 APRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKS 2831
+P + + E + + +G + + + ++ ++P G++AP K+
Sbjct: 1349 SPSPEEEE---EEEEEGSGEGASGRRGRVRV---RLPRVGLAAPSKA 1389
Score = 207 bits (526), Expect = 3e-52
Identities = 383/1545 (24%), Positives = 630/1545 (40%), Gaps = 346/1545 (22%)
Query: 2085 DLKGPQVDIKGPKLDLKDP-KVEMRVPD---VEVSLPSMEVDVQAPRAKLDSAHLQGDLT 2140
++KGP+ + + P K + VP V L ++V+ P+ L+ +
Sbjct: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
Query: 2141 LANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPP---KVEADMSLPSMQGDLK 2197
+ ++P+ ++ A + A+ PP KVEA+++ + +
Sbjct: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAP--PPRKAKVEAEVAAGA-RFTAP 232
Query: 2198 TTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQM-----PSFKVPKVDLK 2252
+L + P +V QV G HLP L + P+ + P V ++
Sbjct: 233 QVEL-VGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQ 291
Query: 2253 GPEIDIKG----------PKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLD------ 2296
P++++ P L+ ++ V V P ++V+ P+V VD+ PGA+++
Sbjct: 292 VPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351
Query: 2297 --------------GARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASAD 2342
GAR + +++ A + +++ K P+ +M +FG+S L + A+ +
Sbjct: 352 EVALKMPRLSFPRFGARAK-EVAEAKVAKVSPEARVKGPRLRMPTFGLSLL-EPRPAAPE 409
Query: 2343 VSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGP------VPEGAG 2396
V VE+ + LP+ +K L + +++V G +VKLP+ P VPE A
Sbjct: 410 V----VESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVPEAAL 460
Query: 2397 LKGHLPKLQMPS---FKMPKV-DLKGPQI---DVKGPKL-DLKGPKTDVMAPDVEVSQPS 2448
+ LP++++P K+PKV ++ P++ +V+ PK+ ++K PK MA EV P
Sbjct: 461 PEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVP-EVRLPE 519
Query: 2449 VEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASV-D 2507
V++ L V++ + K +P+ ++P + + V +
Sbjct: 520 VQL-----------------LKVSEMKLP-KVPEMAVPEVRLPEVQLPKVSEMKLPEVSE 561
Query: 2508 VSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQV-DVKLPEGPVPEGAGLKGHL 2566
V+ P+V ++K ++ + P ++++ ++ +V+LP+ VPE A HL
Sbjct: 562 VAVPEVRLPEVQLPKVPEMKVPEMKL-PKVPEMKLPEMKLPEVQLPK--VPEMAVPDVHL 618
Query: 2567 PKVQMPSFKMPEMDLKGPQL-DVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKL 2625
P+VQ+P K+PEM L +L +VK PK+ E+ PDV + +VQ P+
Sbjct: 619 PEVQLP--KVPEMKLPEMKLPEVKLPKVP------EMAVPDVHLP------EVQLPKVP- 663
Query: 2626 DGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFR---VSAPGESIEALVDVSELKVEADM 2682
++ L KMP+ +P R V P S L V E+ V D+
Sbjct: 664 -------EMKLP-----------KMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMAVP-DV 704
Query: 2683 SLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPE---GHVPEGAGLKGHLPKLQMPSF 2739
LP +Q P +++V D+KLPE VPE A HLP++Q+P
Sbjct: 705 HLPEVQ----------LPKVCEMKVP----DMKLPEIKLPKVPEMAVPDVHLPEVQLP-- 748
Query: 2740 KMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDL 2799
K+ E+ L Q+ K P+V L PKA P+VK+ +AP +L + E
Sbjct: 749 KVSEIRLPEMQVP-KVPDVHL--PKA----PEVKLP--------RAPEVQLKATKAE--- 790
Query: 2800 SLADKGMTAKDSKFKMPKFKMPSFGVS---APGKSIEASVDVSELKVEADGSFPSMQGDL 2856
+GM + FKMPK MP G + + GK EA +VS V P + G+
Sbjct: 791 --QAEGM---EFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEA 845
Query: 2857 KTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVD-LKGPQ 2915
+ PS +L++ P GL+G Q+P+ KM K + ++GP+
Sbjct: 846 HVGVPSLTLPSVELDL--------------PGALGLQG-----QVPAAKMGKGERVEGPE 886
Query: 2916 IDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKD 2975
+ ++ + P E+ P LP+VE++ EG L + + V
Sbjct: 887 VAAGVREVGFRVPSVEIVTPQ----LPAVEIE-------------EGRLEMIETKVKPSS 929
Query: 2976 SKFKMPKFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQL 3035
KF +P FG+S P K EAE + + + LK + +I P A++
Sbjct: 930 ------KFSLPKFGLSGP----------KVAKAEAEGAGRATK--LKVSKFAISLPKARV 971
Query: 3036 EVQAGQVDLKLPEGHVPEGAGLKGHLPKLQM--PSFKMP------KVDRKGPQIDVKGPK 3087
+A +GAG G LP L + P + KV+ G + KGP+
Sbjct: 972 GAEAEA-----------KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPR 1020
Query: 3088 LDLKGPKTDVTAPDVEVSQ--PGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKM 3145
L PK V D E ++ PG+ ++E G DG + KM
Sbjct: 1021 FAL--PKFGVRGRDTEAAELVPGV-AELEGKGWGWDG-------------------RVKM 1058
Query: 3146 PKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQA- 3204
PK KMPSFG+ A GK EV D ++P +A+ S LK ++ + AQ E +A
Sbjct: 1059 PKLKMPSFGL-ARGKEAEVQGDRASPGEKAE----STAVQLKIPEVELVTLGAQEEGRAE 1113
Query: 3205 GQVDVKLPE--GHVLEGAG---LKGHLPKLQMPSFKMPKVDRKGPQIDIKG-PKLDLKGP 3258
G V V + G + AG +GH L+MP + PQ+++ G + G
Sbjct: 1114 GAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISL-----PQVELTGFGEAGTPGQ 1168
Query: 3259 KMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSY 3318
+ T P E V V L GA++ G L + V FKMP +P
Sbjct: 1169 QAQSTVPSAE-GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQL 1221
Query: 3319 RASAPGKSIQASVDVSAP-KAEADVSLPSMQGDLKT-------------TDLSIQLPSVD 3364
G S +A +A + + LP++ + + LP V+
Sbjct: 1222 ELDV-GLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVE 1280
Query: 3365 LEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVD-IKGPKLDLK-- 3421
L G E V EG G GH KV +P F + + + + + K PKL L
Sbjct: 1281 LSPSGGNH----AEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRV 1336
Query: 3422 -VPKAEVTVPDVEVSLPSVE-----------------VDVQAPRAKLDGARL-----EGD 3458
++E+ + S E V V+ PR L EGD
Sbjct: 1337 GFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGD 1396
Query: 3459 LSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKV 3503
+ + V K KF+ P+ + S G E L V P V
Sbjct: 1397 AA-PKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
Score = 207 bits (526), Expect = 3e-52
Identities = 355/1459 (24%), Positives = 607/1459 (41%), Gaps = 278/1459 (19%)
Query: 779 DLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKF 838
++KGP+A+V +++ SLS ++ P A + DL+ D E F PKF
Sbjct: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGA----LGVPADLAPVDVE-------FSFPKF 163
Query: 839 KMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVD 898
G+ A V P A L+ +++ + +A L A
Sbjct: 164 SRLRRGLKAEA--------VKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPR 215
Query: 899 VKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQID--------------------- 937
E V AG + P+VE+ ++P ++ PQ+
Sbjct: 216 KAKVEAEV--AAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTL 273
Query: 938 ---------VKGPKLDLKGPKAEVTAPDGEVSLPSM--------EVDVQAQKAKLDGAWL 980
V+ P + ++ P+ E+ A +LP++ V V + +
Sbjct: 274 GLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTV 333
Query: 981 EGDLSLADKDVTAK----DSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPS 1036
DL+L +V A+ + KMP+ P FG A K + + KV + +
Sbjct: 334 GVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARA-----KEVAEAKVAKVSPEARVKG 388
Query: 1037 MQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVAL 1096
+ + T LS+ P PE K LP ++MPS + +
Sbjct: 389 PRLRMPTFGLSLLE----------------PRPAAPEVVESKLKLPTIKMPSL---GIGV 429
Query: 1097 KGPQVDV-KGPKLDLKSPKA-EVTAPDV-EVSLPSVEV-DVEAPGAKLDSARLEGELSLA 1152
GP+V V KGP ++K PKA EV P V E +LP V + +VE P K+ +L +A
Sbjct: 430 SGPEVKVPKGP--EVKLPKAPEVKLPKVPEAALPEVRLPEVELP--KVSEMKLPKVPEMA 485
Query: 1153 DKDV------TAKDSRFKMPKF-KMPSFGASAPGKSIEASVDVSAPKVE----ADVSLPS 1201
+V K S K+PK +M P + ++ PKV +V LP
Sbjct: 486 VPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPE 545
Query: 1202 MQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKV-D 1260
+Q K +++ + P +++ V +V+L E +P+ +P++++P +K+PKV +
Sbjct: 546 VQLP-KVSEMKL-PEVSEVAV----PEVRLPEVQLPK-------VPEMKVPEMKLPKVPE 592
Query: 1261 LKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKD 1320
+K P++++ +L A H V LP V +M+ P KL +L +A D
Sbjct: 593 MKLPEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKLPKVPEMAVPD 651
Query: 1321 VTAKDSKF-KMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQ 1379
V + + K+P+ K+P A + V L PKV ++M LP K ++++
Sbjct: 652 VHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL--PKV-SEMKLP------KVPEMAVP 702
Query: 1380 PPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEI---DIKGP 1436
DV LPE +P+ +K +P +++P K+PKV PE+ D+ P
Sbjct: 703 -------------DVHLPEVQLPKVCEMK--VPDMKLPEIKLPKV----PEMAVPDVHLP 743
Query: 1437 KLDLKDPKV-EVTAPDVEV-SLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFK 1494
++ L PKV E+ P+++V +P V + +AP KL + + + + FK
Sbjct: 744 EVQL--PKVSEIRLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKATKAEQAEGMEFGFK 800
Query: 1495 MPKFKMPSFGVS---APGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLE 1551
MPK MP G + + GK EA +VS V P + G+ S+ PS +L+
Sbjct: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELD 860
Query: 1552 VQA-----GQVD-VKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL 1605
+ GQV K+ +G EG + + +V F++P V++ PQ+ P +++
Sbjct: 861 LPGALGLQGQVPAAKMGKGERVEGPEVAAGVREV---GFRVPSVEIVTPQL----PAVEI 913
Query: 1606 KGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKF--KMPKF 1663
+ ++E+ VK S K+ A+ EG A +A K SKF +PK
Sbjct: 914 EEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEG----AGRATKLKVSKFAISLPKA 969
Query: 1664 KMPSFGVSAPGK-----SIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADL--- 1715
++ G A K + ++D+S P++ D LPS + ++ DL + P L
Sbjct: 970 RV---GAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKF 1026
Query: 1716 -----EVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVAL-KGPQMDVKGPKLD 1769
+ +A ++ +P EG G+ G +V+MP LKMP L +G + +V+G +
Sbjct: 1027 GVRGRDTEAAEL---VPGVAELEGKGW-GWDGRVKMPKLKMPSFGLARGKEAEVQGDRAS 1082
Query: 1770 LKGPKAEVMA-----PDVEVSLPSVEVDVEAPGA-KLDSVRLEG-DLSLADKDVTAKDSK 1822
G KAE A P+VE+ + + A GA + ++L G +S A + VT
Sbjct: 1083 -PGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHD- 1140
Query: 1823 FKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVV 1882
+MP G+S P + + P +A+ ++PS +G +A V
Sbjct: 1141 ---AGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEG------------TAGYRV 1185
Query: 1883 QAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEV 1942
Q QV + LP QV G L G FKMP V + + DV G + + +A
Sbjct: 1186 QVPQVTLSLPGAQVAGGELLVGE------GVFKMPTVTVPQLELDV-GLSREAQAGEAAT 1238
Query: 1943 TAPDVEVSLPSM----EVDVQAQKAKLDGARLEGDLSLADKDMT---AKDSKFKMP---- 1991
+ + LP++ V + + + GA LSL D +++ +++++
Sbjct: 1239 GEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEG 1298
Query: 1992 ------KFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSM---QGDLKTTDLSIQPPS 2042
K ++P FG+ E +PK+ LP + Q ++ T + S P
Sbjct: 1299 EAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLR----LPRVGFSQSEMVTGEGSPSPEE 1354
Query: 2043 ADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKG------P 2096
+ + + G G G G +V +++P+V L P +G P
Sbjct: 1355 EEEEEEEG------------SGEGASGRRGRVR---VRLPRVGLAAPSKASRGQEGDAAP 1399
Query: 2097 KLDLKDPKVEMRVPDVEVS 2115
K +++ + R P V +S
Sbjct: 1400 KSPVREKSPKFRFPRVSLS 1418
Score = 204 bits (519), Expect = 2e-51
Identities = 348/1426 (24%), Positives = 590/1426 (41%), Gaps = 328/1426 (23%)
Query: 1274 DLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKF 1333
++KG +A+V + SL V+ PGA L LA DV KF +
Sbjct: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGA------LGVPADLAPVDVEFSFPKFSRLRR 168
Query: 1334 KMPSFGVSAPGKSIEASVDLSAPKVEA-DMSLPSMQGDLKTTDLSIQPPSTDLELQAGQ- 1391
+ + V P + A L P++ +++ + L + + E+ AG
Sbjct: 169 GLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGAR 228
Query: 1392 ---------------LDVKLPEGPVPEGA-------GLKGHLPKLQM-----PSFKVPKV 1424
+V +P+ P+ A G HLP L + P+ + P V
Sbjct: 229 FTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAV 288
Query: 1425 DLKGPEIDIKG----------PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDG-- 1472
++ P++++ P L+ ++ V V P ++V+ P+V VD+ PGA+++
Sbjct: 289 GIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARG 348
Query: 1473 -----------------GRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEAS 1515
G ++++ A + +++ K P+ +MP+FG+S
Sbjct: 349 EAPEVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSL------LE 402
Query: 1516 VDVSAPK-VEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP-VSEGAGLK 1573
+AP+ VE+ + LP+ +K L I +++V G +VKLP+ P V +
Sbjct: 403 PRPAAPEVVESKLKLPT----IKMPSLGIGVSGPEVKVPKGP-EVKLPKAPEVKLPKVPE 457
Query: 1574 GHLPKVQMPSFKMPKV-DLKGPQI-DVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAP 1631
LP+V++P ++PKV ++K P++ ++ P++ L P+VE+ P V ++ P
Sbjct: 458 AALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL--PEVEL--PKVSEMKLPKVPEMAVP 513
Query: 1632 RAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVE-A 1690
+L QL K S+ K+P K+P V P+V
Sbjct: 514 EVRLPEVQL------------LKVSEMKLP--KVPEMAV---------------PEVRLP 544
Query: 1691 DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLK 1750
+V LP + ++K ++S + V+LPE LP+ +P++++P +K
Sbjct: 545 EVQLPKV-SEMKLPEVS----------EVAVPEVRLPEVQLPK-------VPEMKVPEMK 586
Query: 1751 MPKV-ALKGPQMDVKGPKLDLKGPKAEVMA-PDV---EVSLPSVEVDVEAPGAKLDSVRL 1805
+PKV +K P+M K P++ L PK MA PDV EV LP V +++ P KL V+L
Sbjct: 587 LPKVPEMKLPEM--KLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLPEMKLPEVKL 641
Query: 1806 EGDLSLADKDVTAKDSKF-KMPKFKMPSF-GVSAPGKSIEASVDVSAPKVEAEVSLPSMQ 1863
+A DV + + K+P+ K+P ++ P + +V PKV +E+ LP +
Sbjct: 642 PKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLP---EVQLPKV-SEMKLPKVP 697
Query: 1864 GDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKV-DLK 1922
++ D+ +P V + DMKLPE ++P+ + +P V +P ++PKV +++
Sbjct: 698 -EMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMA--VPDVHLPEVQLPKVSEIR 754
Query: 1923 GPQTDVKGAKLDLKGPKAEVTAPDVEVSLP-SMEVDVQAQKAKLDGARLEGDLSLADKDM 1981
P+ V D+ PKA EV LP + EV ++A KA+ + EG
Sbjct: 755 LPEMQVPKVP-DVHLPKAP------EVKLPRAPEVQLKATKAE----QAEG--------- 794
Query: 1982 TAKDSKFKMPKFKMPSFGVS---APGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSI 2038
+ FKMPK MP G + + G+ EA +V V P + G+ S+
Sbjct: 795 --MEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSL 852
Query: 2039 QPPSADLKVQ-----TGQVD-VKLPEGHVPEG----AGLKG---HLPKVEMPSLKMPKVD 2085
PS +L + GQV K+ +G EG AG++ +P VE+ + ++P V+
Sbjct: 853 TLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVE 912
Query: 2086 LK-----------GPQVDIKGPKLDLKDPKV------------EMRVPDVEVSLPSMEV- 2121
++ P PK L PKV +++V +SLP V
Sbjct: 913 IEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVG 972
Query: 2122 -----------------DVQAPRAKLDSAHLQGDLTLANKDLTTK--------------- 2149
D+ P+ LD+ G + +A DL K
Sbjct: 973 AEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRD 1032
Query: 2150 --------------------DSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSL 2189
D + KMPK KMPSFG+ A GK E D + P +A+
Sbjct: 1033 TEAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAE--- 1088
Query: 2190 PSMQGDLKTTDLSIQPLSADVK------VQAGQVDVKLLEGPVPEEVGLKGHLPKLQMP- 2242
S LK ++ + L A + V + + L+ +V +GH L+MP
Sbjct: 1089 -STAVQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPP 1147
Query: 2243 -SFKVPKVDLKG-PEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARL 2300
+P+V+L G E G + P E TA V +P +V + PGA++ G L
Sbjct: 1148 LGISLPQVELTGFGEAGTPGQQAQSTVPSAEGTA-GYRVQVP--QVTLSLPGAQVAGGEL 1204
Query: 2301 EGDMSLADKDVTAKDSKFKMPKFKM----LSFGVSALGKSIEASADVSALKVEADVSLPS 2356
+ FKMP + L G+S ++ EA+ L+++ LP+
Sbjct: 1205 -----------LVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLK----LPT 1249
Query: 2357 MQGDLKT--TDLSVQPPSADLEVQAGQVDVKL-PEG------PVPEGAGLKGHLPKLQMP 2407
+ + QPP A+ DV+L P G V EG G GH K+++P
Sbjct: 1250 LGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLP 1309
Query: 2408 SFKMPKVDLKGPQID-VKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLE 2466
F + + + + K PKL L P V SQ + +P + + E
Sbjct: 1310 RFGLVRAKEGAEEGEKAKSPKLRL---------PRVGFSQSEMVTGEGSPSPEEEE---E 1357
Query: 2467 GDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPK 2512
+ + + + + R ++ ++P G++AP K+ +APK
Sbjct: 1358 EEEEGSGEGASGRRGRVRV---RLPRVGLAAPSKASRGQEGDAAPK 1400
Score = 202 bits (515), Expect = 6e-51
Identities = 371/1533 (24%), Positives = 618/1533 (40%), Gaps = 336/1533 (21%)
Query: 2594 DLKGPKAEVTAPDVEMSLSSMEVDVQAPRA---KLDGARLEGDLSLAD-----KGVTAKD 2645
++KGP+A+V +++ SLS ++ P A D A ++ + S +G+ A+
Sbjct: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEA 174
Query: 2646 SKFKMP------KFKMPSFRVSAPGESIEALVDVS------ELKVEADMSLPSMQGDLKT 2693
K +P + ++P RV E +A + + KVEA+++ + +
Sbjct: 175 VKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQV 234
Query: 2694 TDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQM-----PSFKMPEVDLKG 2748
+ + P A++ V P G L HLP L + P+ + P V ++
Sbjct: 235 ELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFAL--HLPTLGLGAPAPPAVEAPAVGIQV 292
Query: 2749 PQIDVKG----------PNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGD 2798
PQ+++ P ++ + V P + ++ ++ VD+ P A+++ AR E
Sbjct: 293 PQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVE-ARGE-- 349
Query: 2799 LSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKT 2858
A + KMP+ P FG A +V+E KV ++G
Sbjct: 350 ---------APEVALKMPRLSFPRFGARAK--------EVAEAKVAKVSPEARVKGP--- 389
Query: 2859 TDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDV 2918
R++ P+ L + P PE K LP ++MPS + + GP++ V
Sbjct: 390 ---RLRMPTFGLSLLE-------PRPAAPEVVESKLKLPTIKMPSLG---IGVSGPEVKV 436
Query: 2919 -KGPKLDLKGPKA-EVTAPDV-EVSLPSVEV-DVEAPRAKLDGARLEGDLSLADKDVTA- 2973
KGP++ L PKA EV P V E +LP V + +VE P K+ +L +A +V
Sbjct: 437 PKGPEVKL--PKAPEVKLPKVPEAALPEVRLPEVELP--KVSEMKLPKVPEMAVPEVRLP 492
Query: 2974 -----KDSKFKMPKF-KMPSFGVSAPGKSIEVSVDVSAPKVEA----EVSLPSMQ----G 3019
K S+ K+PK +M V P + ++ PKV EV LP +Q
Sbjct: 493 EVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVS 552
Query: 3020 DLKTTDIS-IEPPSAQL-EVQAGQV-DLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDR 3076
++K ++S + P +L EVQ +V ++K+PE +P+ +K LP++++P ++PKV
Sbjct: 553 EMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMK--LPEMKLPEVQLPKV-- 608
Query: 3077 KGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDV 3136
P++ V DV P+V++ + +++ P KL +L +A DV
Sbjct: 609 --PEMAVP-----------DVHLPEVQLPKVP---EMKLPEMKLPEVKLPKVPEMAVPDV 652
Query: 3137 TAKDSKF-KMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEP 3195
+ + K+P+ K+P A + L +V PKV +++ LP +
Sbjct: 653 HLPEVQLPKVPEMKLPKMPEMAVPEVR--LPEVQLPKV-SEMKLPKVP------------ 697
Query: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKG-PQI---DIKGP 3251
+ DV LPE + + +K +P +++P K+PKV P + +++ P
Sbjct: 698 -------EMAVPDVHLPEVQLPKVCEMK--VPDMKLPEIKLPKVPEMAVPDVHLPEVQLP 748
Query: 3252 KL-DLKGPKMDVT-APDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFK 3309
K+ +++ P+M V PDV + + AP +L + E + FK
Sbjct: 749 KVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAE--------QAEGMEFGFK 800
Query: 3310 MPKFKMPSY-RASAP--GKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLE 3366
MPK MP RA +P GK +A +VS P + G+ S+ LPSV+L+
Sbjct: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELD 860
Query: 3367 VQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAE 3426
+ P GL+G +P +M + ++ P+V ++ +VP E
Sbjct: 861 L--------------PGALGLQGQVPAAKMGKGER----VEGPEVAAGVREVGFRVPSVE 902
Query: 3427 VTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVS 3486
+ P LP+VE++ EG L + E V KF +P FG+S
Sbjct: 903 IVTPQ----LPAVEIE-------------EGRLEMIETKVKPSS------KFSLPKFGLS 939
Query: 3487 APGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPV 3546
P V+ + +G +AT L + + L V + E
Sbjct: 940 GP-----------------KVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEA----- 977
Query: 3547 PEGAGLKGHLPKVEMP--------SLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVE 3598
+GAG G LP +++ L + KV++ G + KGP+ L PK VR D E
Sbjct: 978 -KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFAL--PKFGVRGRDTE 1034
Query: 3599 VS--LPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKS 3656
+ +P V LEG D + KMPK KMPSF + A GK
Sbjct: 1035 AAELVPGV-------------AELEGK-------GWGWDGRVKMPKLKMPSFGL-ARGKE 1073
Query: 3657 MEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEG-- 3714
E D ++P +A+ +T + ++ P +L V G + EG V
Sbjct: 1074 AEVQGDRASPGEKAE-----------STAVQLKIPEVEL-VTLGAQEEGRAEGAVAVSGM 1121
Query: 3715 --AGLK-----EHLPKVEMPSLKMPKVDLKGPQVDIKG-PKLDLKVSKAEVTAPDVEVSL 3766
+GLK + + + L+MP + + PQV++ G + +A+ T P E
Sbjct: 1122 QLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAE-GT 1180
Query: 3767 PSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSF----GVSAPGKSI 3822
V V L AQ+ G L + V FKMP +P G+S ++
Sbjct: 1181 AGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQLELDVGLSREAQAG 1234
Query: 3823 EASVHVSAPKVEADVSLPSMQGDLKT--TDLSIQPHSADLTVQARQVDMKL-------LE 3873
EA+ +++ LP++ + QP A+ T D++L E
Sbjct: 1235 EAATGEGGLRLK----LPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAE 1290
Query: 3874 GHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEID-IKGPKLDLKDPKVEVTAPDVEVSLP 3932
V E G GH KV++P F + + E + K PKL L P+V + ++
Sbjct: 1291 YQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRL--PRVGFSQSEMVTGEG 1348
Query: 3933 SV------EVDVEAPGAKLDGAR---------------------LEGDLSLADKDMTAKD 3965
S E + E G G R EGD + + K
Sbjct: 1349 SPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA-PKSPVREKS 1407
Query: 3966 SKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKV 3998
KF+ P+ + S G E + V P V
Sbjct: 1408 PKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
Score = 202 bits (514), Expect = 8e-51
Identities = 383/1533 (24%), Positives = 630/1533 (41%), Gaps = 368/1533 (24%)
Query: 944 DLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKF 1003
++KGP+A+V ++++Q+ + G L + D+ D +F PKF
Sbjct: 116 EIKGPRAKVA-----------KLNIQSLSPVKKKKMVPGALGVP-ADLAPVDVEFSFPKF 163
Query: 1004 KMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQ-----GDLKTTDLSIQ-PASTDLKV 1057
G+ A +++K V A L LP ++ + + L+ P KV
Sbjct: 164 SRLRRGLKA--EAVKG--PVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKV 219
Query: 1058 QADQV--------------------DVKLPEGHLPEGA-------GLKGHLPKVEM---- 1086
+A+ +V +P+ P+ A G HLP + +
Sbjct: 220 EAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPA 279
Query: 1087 -PSFKMPKVALKGPQVDVKG----------PKLDLKSPKAEVTAPDVEVSLPSVEVDVEA 1135
P+ + P V ++ PQV++ P L+ + V P ++V+ P+V VD+
Sbjct: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339
Query: 1136 PGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEA 1195
PGA++++ GE A + KMP+ P FGA A + EA V +P EA
Sbjct: 340 PGAEVEA---RGE---------APEVALKMPRLSFPRFGARAK-EVAEAKVAKVSP--EA 384
Query: 1196 DVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLK 1255
V P ++ + T LS+ P PE K LP ++MPSL
Sbjct: 385 RVKGPRLR--MPTFGLSLLEP----------------RPAAPEVVESKLKLPTIKMPSL- 425
Query: 1256 MPKVDLKGPQVEV-RGPKLDLKGHKAEVTAHEV------AVSLPSVEV------------ 1296
+ + GP+V+V +GP++ L EV +V V LP VE+
Sbjct: 426 --GIGVSGPEVKVPKGPEVKLP-KAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVP 482
Query: 1297 DMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKF-KMPSFGVSAPGKSIEASVDLSA 1355
+M P +L +L K S+ K+PK +M V P + ++
Sbjct: 483 EMAVPEVRLPEVEL------------PKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKL 530
Query: 1356 PKVEADMSLPSMQGDLKTTDLSIQPPSTDLEL----QAGQLDVKLPEGPVPEGAGLKGHL 1411
PKV +M++P ++ L L P ++++L + +V+LPE +P+ +
Sbjct: 531 PKV-PEMAVPEVR--LPEVQL---PKVSEMKLPEVSEVAVPEVRLPEVQLPK-------V 577
Query: 1412 PKLQMPSFKVPKV-DLKGPEIDIKGPKLDLKDPKV-EVTAPDV---EVSLPSVEVDVEAP 1466
P++++P K+PKV ++K PE +K P++ L PKV E+ PDV EV LP V +++ P
Sbjct: 578 PEMKVPEMKLPKVPEMKLPE--MKLPEVQL--PKVPEMAVPDVHLPEVQLPKVP-EMKLP 632
Query: 1467 GAKLDGGRLEEDMSLADKDLTTKDSKF-KMPKFKMPSF-GVSAPGKSIEASVDVSAPKVE 1524
KL +L + +A D+ + + K+P+ K+P ++ P + +V PKV
Sbjct: 633 EMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLP---EVQLPKV- 688
Query: 1525 ADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPE---GPVSEGAGLKGHLPKVQM 1581
+++ LP + ++ D+ + + D+KLPE V E A HLP+VQ+
Sbjct: 689 SEMKLPKVP-EMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQL 747
Query: 1582 PSFKMPKVDLKGPQIDVKGPKL-DLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQL 1640
P +++ P++ V PK+ D+ PK AP+VK+ + EV ++A +A+ Q
Sbjct: 748 PKVS----EIRLPEMQV--PKVPDVHLPK----APEVKLP-RAPEVQLKATKAE----QA 792
Query: 1641 EGDLSLADKAVTAKDSKFKMPKFKMPSFGVS---APGKSIEASVDVSEPKVEADVSLPSM 1697
EG + FKMPK MP G + + GK EA +VS V+LP +
Sbjct: 793 EG-----------MEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL----VTLPCL 837
Query: 1698 QGDLKTTDLSIQSPSADLEVQAGQVNVKLP--EGPLPEGAGFKGHLPKVQMPSLKMPK-V 1754
Q P D E G ++ LP E LP G +G Q+P+ KM K
Sbjct: 838 Q------------PEVDGEAHVGVPSLTLPSVELDLPGALGLQG-----QVPAAKMGKGE 880
Query: 1755 ALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADK 1814
++GP++ ++ + P E++ P LP+VE++ EG L + +
Sbjct: 881 RVEGPEVAAGVREVGFRVPSVEIVTP----QLPAVEIE-------------EGRLEMIET 923
Query: 1815 DVTAKDSKFKMPKF-----KMPSFGVSAPGKSIEASVD---VSAPK----VEAEVSLPSM 1862
V SKF +PKF K+ G++ + V +S PK EAE
Sbjct: 924 KV-KPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGE 982
Query: 1863 QGDLKTTDLCIP-------LPSADLVVQAGQVDMKLPEGQVP------------------ 1897
G L DL IP LPS + V + K P +P
Sbjct: 983 AGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGV 1042
Query: 1898 ---EGAGLKGHLPKVDMPSFKMPKVDL-KGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPS 1953
EG G G +V MP KMP L +G + +V+G + G KAE TA V++ +P
Sbjct: 1043 AELEGKGW-GWDGRVKMPKLKMPSFGLARGKEAEVQGDRAS-PGEKAESTA--VQLKIPE 1098
Query: 1954 ME-VDVQAQ-KAKLDGARLEGDLSLADKDMTAKD---SKFKMPKFKMPSFGVSAPGRSIE 2008
+E V + AQ + + +GA + L+ ++ ++ +MP G+S P +
Sbjct: 1099 VELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELT 1158
Query: 2009 ASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLK 2068
+ P +A ++PS +G +A +VQ QV + LP V G L
Sbjct: 1159 GFGEAGTPGQQAQSTVPSAEG------------TAGYRVQVPQVTLSLPGAQVAGGELLV 1206
Query: 2069 GH----LPKVEMPSLKMP---------------------KVDLKGPQVDIKGPKLDLKDP 2103
G +P V +P L++ K+ G + + G + + P
Sbjct: 1207 GEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPP 1266
Query: 2104 KVE----MRVPDVEVSLPS--MEVDVQAPRAKLDSAH-----LQGDLTLANKDLTTKDSK 2152
E + +PDVE+S PS + Q + ++ H L + K+ + K
Sbjct: 1267 GAERTFCLSLPDVELS-PSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEK 1325
Query: 2153 FKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQG-----DLKTTDLSIQPLS 2207
K PK ++P G S + + SP + E + S +G L L+
Sbjct: 1326 AKSPKLRLPRVGFS-QSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLA 1384
Query: 2208 ADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKD 2267
A K GQ + PV E + P F+ P+V L G D ++
Sbjct: 1385 APSKASRGQEGDAAPKSPVRE-----------KSPKFRFPRVSLSPKARSGSG---DQEE 1430
Query: 2268 PKVEVTAPDVEVSLPSVEVDVKAPG-AKLDGAR 2299
+ V P V S + APG A+++GA+
Sbjct: 1431 GGLRVRLPSVGFS------ETGAPGPARMEGAQ 1457
Score = 188 bits (478), Expect = 1e-46
Identities = 342/1444 (23%), Positives = 600/1444 (41%), Gaps = 286/1444 (19%)
Query: 3254 DLKGPKMDVTAPDVEVSQPSMEVDVE--APGAKLDGARLEGDLSLAD-----KDVTAKDS 3306
++KGP+ V +++ P + + A G D A ++ + S + + A+
Sbjct: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175
Query: 3307 KFKMP------KFKMPSYRASAPGKSIQAS-VDVSAP-----KAEADVSLPSMQGDLKTT 3354
K +P + ++P R + QA+ + +AP K EA+V+ + +
Sbjct: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235
Query: 3355 DLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEM-----PSFKMPKVDLKSP 3409
+ +LP ++ V P G L HLP + + P+ + P V ++ P
Sbjct: 236 LVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFAL--HLPTLGLGAPAPPAVEAPAVGIQVP 293
Query: 3410 QVDIKG----------PKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDL 3459
QV++ P L+ + V VP ++V+ P+V VD+ P A+++ AR E
Sbjct: 294 QVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVE-ARGE--- 349
Query: 3460 SLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKAT 3519
A + KMP+ P FG A K A+ ++ + + +
Sbjct: 350 --------APEVALKMPRLSFPRFGARA--------------KEVAEAKVAKVSPEARVK 387
Query: 3520 DLSIQPPSADLEVQAVQVDVELLEG--PVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQID 3577
++ P+ L LLE PE K LP ++MPSL + + GP++
Sbjct: 388 GPRLRMPTFGLS---------LLEPRPAAPEVVESKLKLPTIKMPSLG---IGVSGPEVK 435
Query: 3578 V-KGPKLDLKGPKA-EVRVPDV-EVSLPSVEV-DVQAPKAKLDAGRLEGDLSLADKDVTA 3633
V KGP++ L PKA EV++P V E +LP V + +V+ PK ++ L
Sbjct: 436 VPKGPEVKL--PKAPEVKLPKVPEAALPEVRLPEVELPKVS--------EMKLP------ 479
Query: 3634 KDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEA----DVSLPSMQGDLKTTDLSIQ 3689
K+P+ +P R+ P + ++ PKV +V LP +Q LK +++ +
Sbjct: 480 -----KVPEMAVPEVRL--PEVELPKVSEMKLPKVPEMAVPEVRLPEVQL-LKVSEMKL- 530
Query: 3690 PPSADLKVQAGQMDVKLPEGQVPEGAGLK------EHLPKVEMPSLKMPKV-DLKGPQVD 3742
P ++ V +V+LPE Q+P+ + +K +P+V +P +++PKV ++K P++
Sbjct: 531 PKVPEMAVP----EVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMK 586
Query: 3743 I-KGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDS 3801
+ K P++ L K EV LP V ++ P L QL K
Sbjct: 587 LPKVPEMKLPEMKLP------EVQLPKVP-EMAVPDVHLPEVQLP------------KVP 627
Query: 3802 KFKMPKFKMPSFGVSAPGKSIEASVH---VSAPKVEADVSLPSMQGDLKTTDLSIQPHSA 3858
+ K+P+ K+P + + VH V PKV ++ LP M ++++ P
Sbjct: 628 EMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVP-EMKLPKMP------EMAV-PEVR 679
Query: 3859 DLTVQARQV-DMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKV-DLKGPEIDI-KGPKLDL 3915
VQ +V +MKL + VPE A HLP+VQ+P KV D+K PEI + K P++ +
Sbjct: 680 LPEVQLPKVSEMKLPK--VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAV 737
Query: 3916 KDPKV-EVTAPDV-EVSLPSVEV----DV---EAPGAKLDGARLEGDLSLADKDMTAKDS 3966
D + EV P V E+ LP ++V DV +AP KL A + + +
Sbjct: 738 PDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEF 797
Query: 3967 KFKMPKFKMPSFGVS---APGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSA 4023
FKMPK MP G + + GK EA +V+ V P + G+ S+ PS
Sbjct: 798 GFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSV 857
Query: 4024 DLEVQA-----GQVDV-KLPEGPVPEGASLKG-------HLPKVQMPSFKMPKVDLKGPQ 4070
+L++ GQV K+ +G EG + +P V++ + ++P V+++ +
Sbjct: 858 ELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGR 917
Query: 4071 IDV-----------KGPKLDLKGPK-----AEVTAPDVKMSLSSMEVDVQAPRAKLDG-- 4112
+++ PK L GPK AE K+ +S + + R +
Sbjct: 918 LEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEA 977
Query: 4113 ------------------VQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEA 4154
+ L+ L +V D KFK P+F +P FGV G+ EA
Sbjct: 978 KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVR--GRDTEA 1035
Query: 4155 SV---DVSELKAKA-----DVSLPSMQ----GDLKTTDLSIQSPSADL--EVQAGQVDVK 4200
+ V+EL+ K V +P ++ G + + +Q A + ++ V +K
Sbjct: 1036 AELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDRASPGEKAESTAVQLK 1095
Query: 4201 LPEGPLPK-GAGLKGH------LPKVQMPCLKMP---KVALKGPQVDVKGPKLDLKGPKA 4250
+PE L GA +G + +Q+ LK+ +V +G ++ P L + P+
Sbjct: 1096 IPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQV 1155
Query: 4251 DVMTPVVEVSLPSMEVDVEAPGAK--------LDSVRLE-GDLSLADKDMTAKDSKFKMP 4301
+ +T E P + P A+ + V L +A ++ + FKMP
Sbjct: 1156 E-LTGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMP 1214
Query: 4302 KFKMPSF----GVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKT--THLSIQPPSADL 4355
+P G+S ++ EA+ L+++ LP++ + QPP A+
Sbjct: 1215 TVTVPQLELDVGLSREAQAGEAATGEGGLRLK----LPTLGARARVGGEGAEEQPPGAER 1270
Query: 4356 EVQAGQEDVKL-PEGPVH------EGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKL 4408
DV+L P G H EG G GH K+++P F + + + +
Sbjct: 1271 TFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGE------ 1324
Query: 4409 DLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKF 4468
K PK+ + P + S M + G+ E + + + + + + ++
Sbjct: 1325 KAKSPKLRL--PRVGFSQSEM---VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRV--- 1376
Query: 4469 KMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVD 4528
++P G+ +P K+ +APK P + L +A S + + G +
Sbjct: 1377 RLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFR--FPRVSLSPKARSGSGDQEEGGLR 1434
Query: 4529 LKLP 4532
++LP
Sbjct: 1435 VRLP 1438
Score = 186 bits (472), Expect = 6e-46
Identities = 324/1302 (24%), Positives = 534/1302 (41%), Gaps = 271/1302 (20%)
Query: 686 GASAPGKSMEASVDVSAPKVEA----DVSLLSMQGDLKTTD--LSVQTPSADLEVQDGQV 739
GA AP +V + P+VE + L L+T + +SV P+ D+ V
Sbjct: 276 GAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGV 335
Query: 740 DVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSM 799
D+ LP + +G P+V +LKMP++ P+ G +A+ A + K++ S
Sbjct: 336 DLALPGAEV----EARGEAPEV---ALKMPRLSF--PRF---GARAKEVA-EAKVAKVSP 382
Query: 800 EVDVQAPRAKLDGARLEGDLSLADKEVTAKD---SKFKMPKFKMPSFGVSAPGKSME--- 853
E V+ PR ++ LSL + A + SK K+P KMPS G+ G ++
Sbjct: 383 EARVKGPRLRMPTF----GLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPK 438
Query: 854 -------DSVDVSAPKVE----ADVSLSSMQ-GDLKATDLSIQPPSADLEVQAGQV---- 897
+ +V PKV +V L ++ + L P A EV+ +V
Sbjct: 439 GPEVKLPKAPEVKLPKVPEAALPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPK 498
Query: 898 --DVKLPEGPVPEGAGPKVHLPKVEM---PSFKMPKV-DLKGPQI---DVKGPKL-DLKG 947
++KLP+ VPE A P+V LP+V++ K+PKV ++ P++ +V+ PK+ ++K
Sbjct: 499 VSEMKLPK--VPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKL 556
Query: 948 PK-AEVTAPD-----------GEVSLPSMEV----DVQAQKAKLDGAWLEGDLSLADKDV 991
P+ +EV P+ E+ +P M++ +++ + KL L +A DV
Sbjct: 557 PEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDV 616
Query: 992 ------TAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVE----ADLSLPSMQ--- 1038
K + K+P+ K+P V P A+ DV P+V+ ++ LP M
Sbjct: 617 HLPEVQLPKVPEMKLPEMKLPE--VKLPKVPEMAVPDVHLPEVQLPKVPEMKLPKMPEMA 674
Query: 1039 -GDLKTTDLSIQPASTDLKV----QADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPK 1093
+++ ++ + P +++K+ + DV LPE LP+ +K +P +++P K+PK
Sbjct: 675 VPEVRLPEVQL-PKVSEMKLPKVPEMAVPDVHLPEVQLPKVCEMK--VPDMKLPEIKLPK 731
Query: 1094 VALKGPQVDVKGPKL-DLKSPK-AEVTAPDVEV-SLPSVEVDVEAPGAKLDSARLEGELS 1150
V P++ V L +++ PK +E+ P+++V +P V + +AP KL A +
Sbjct: 732 V----PEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLP-KAPEVKLPRAPEVQLKA 786
Query: 1151 LADKDVTAKDSRFKMPKFKMPSFG-ASAP--GKSIEASVDVSAPKVEADVSLPSMQGDLK 1207
+ + FKMPK MP G A +P GK EA +VS V+LP +Q
Sbjct: 787 TKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL----VTLPCLQ---- 838
Query: 1208 TTDLSIQPPSADLEVHAGQVDVKL--LEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQ 1265
P D E H G + L +E +P G +G +P +M KG +
Sbjct: 839 --------PEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMG---------KGER 881
Query: 1266 VEVRGPKLDLKGHKAEVTAHEVAVSLPSVE-VDMQAPGAKLDGAQLDGDLSLADKDVTAK 1324
VE G + EV +PSVE V Q P +++ +G L + + V
Sbjct: 882 VE---------GPEVAAGVREVGFRVPSVEIVTPQLPAVEIE----EGRLEMIETKV-KP 927
Query: 1325 DSKFKMPKFKMPSFGVS---APGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPP 1381
SKF +PKF + V+ A G + +S + + + + K + P
Sbjct: 928 SSKFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLP 987
Query: 1382 STDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLK 1441
+ DL + LD LP G KV++ G ++ KGP+ L
Sbjct: 988 ALDLSIPQLSLDAHLPSG-----------------------KVEVAGADLKFKGPRFAL- 1023
Query: 1442 DPKVEVTAPDVEVS--LPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFK 1499
PK V D E + +P V ++E G DG + KMPK K
Sbjct: 1024 -PKFGVRGRDTEAAELVPGV-AELEGKGWGWDG-------------------RVKMPKLK 1062
Query: 1500 MPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDV 1559
MPSFG+ A GK E D ++P +A+ +T + ++ P +L Q +
Sbjct: 1063 MPSFGL-ARGKEAEVQGDRASPGEKAE-----------STAVQLKIPEVELVTLGAQEEG 1110
Query: 1560 KLPEGPVSEGAGLKG--------HLPKVQMPSFKMPKVDLKGPQIDVKG-PKLDLKGPKV 1610
+ G L G + + +MP + + PQ+++ G + G +
Sbjct: 1111 RAEGAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQA 1170
Query: 1611 EVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSF-- 1668
+ T P + + V V L GAQ+ G L + V FKMP +P
Sbjct: 1171 QSTVPSAE-GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGV------FKMPTVTVPQLEL 1223
Query: 1669 --GVSAPGKSIEASVDV-----------SEPKVEADVSLPSMQGDLKTTDLSIQ----SP 1711
G+S ++ EA+ + +V + + G +T LS+ SP
Sbjct: 1224 DVGLSREAQAGEAATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSP 1283
Query: 1712 S---------ADLEVQAG-QVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQM 1761
S A+ E +AG ++ V+LP L K + P L++P+V +M
Sbjct: 1284 SGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEM 1343
Query: 1762 ----------DVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSL 1811
+ + + + G A V V LP V + AP S EGD +
Sbjct: 1344 VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLP--RVGLAAPSKA--SRGQEGD-AA 1398
Query: 1812 ADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKV 1853
V K KF+ P+ + S G E + V P V
Sbjct: 1399 PKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440
Score = 178 bits (452), Expect = 1e-43
Identities = 372/1519 (24%), Positives = 616/1519 (40%), Gaps = 340/1519 (22%)
Query: 3584 DLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKF----- 3638
++KGP+A+V +++ P K K+ G L LA DV KF
Sbjct: 116 EIKGPRAKVAKLNIQSLSP-------VKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRR 168
Query: 3639 -------KMP--------KFKMPSFRVSAPGKSMEAS-VDVSAP-----KVEADVSLPSM 3677
K P + ++P RV + +A+ + +AP KVEA+V+ +
Sbjct: 169 GLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGAR 228
Query: 3678 QGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEM-----PSLKMP 3732
+ + + P A++ V P + G L HLP + + P+++ P
Sbjct: 229 FTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFAL--HLPTLGLGAPAPPAVEAP 286
Query: 3733 KVDLKGPQVDIKG----------PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDS 3782
V ++ PQV++ P L+ + V P ++V+ P+V VD+ P A++++
Sbjct: 287 AVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEA 346
Query: 3783 AQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLPSM 3842
+++L KMP+ P FG A + EA V +P EA V P +
Sbjct: 347 RGEAPEVAL------------KMPRLSFPRFGARAK-EVAEAKVAKVSP--EARVKGPRL 391
Query: 3843 QGDLKTTDLSI-QPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDL 3901
+ + T LS+ +P A PE K LP ++MPS + +
Sbjct: 392 R--MPTFGLSLLEPRPA-----------------APEVVESKLKLPTIKMPSLG---IGV 429
Query: 3902 KGPEIDI-KGPKLDLKDPKV-EVTAPDV-EVSLPSVEV-DVEAPGAKLDGARLEGDLSLA 3957
GPE+ + KGP++ L PK EV P V E +LP V + +VE P K+ +L +A
Sbjct: 430 SGPEVKVPKGPEVKL--PKAPEVKLPKVPEAALPEVRLPEVELP--KVSEMKLPKVPEMA 485
Query: 3958 DKDMTA------KDSKFKMPKF-KMPSFGVSAPGKSMEASVDVTAPKVEA----DVSLPS 4006
++ K S+ K+PK +M V P + ++ PKV +V LP
Sbjct: 486 VPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPE 545
Query: 4007 MQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKV-D 4065
+Q K +++ + P +++ V +V+LPE +P+ +P++++P K+PKV +
Sbjct: 546 VQLP-KVSEMKL-PEVSEVAVP----EVRLPEVQLPK-------VPEMKVPEMKLPKVPE 592
Query: 4066 LKGPQIDVKGPKLDLKGPKA-EVTAPDVKMSLSSMEV--DVQAPRAKLDGVQLEGDLSLA 4122
+K P++ K P++ L PK E+ PDV + + +++ P KL V+L +A
Sbjct: 593 MKLPEM--KLPEVQL--PKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMA 648
Query: 4123 DKDVTAKDSKF-KMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDL 4181
DV + + K+P+ K+P A E + +L +++ LP + ++ D+
Sbjct: 649 VPDVHLPEVQLPKVPEMKLPKMPEMAVP---EVRLPEVQLPKVSEMKLPKVP-EMAVPDV 704
Query: 4182 SIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVA-LKGPQVDVKG 4240
+ + D+KLPE LPK + +P V +P +++PKV+ ++ P++ V
Sbjct: 705 HLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMA--VPDVHLPEVQLPKVSEIRLPEMQV-- 760
Query: 4241 PKL-DLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFK 4299
PK+ D+ PKA EV LP AP +L + + E + FK
Sbjct: 761 PKVPDVHLPKAP------EVKLP------RAPEVQLKATKAE--------QAEGMEFGFK 800
Query: 4300 MPKFKMPSFGVS---APGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLE 4356
MPK MP G + + GK EA +VS V P + G+ S+ PS +L+
Sbjct: 801 MPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELD 860
Query: 4357 VQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVD-LKGPQIDVNVPKLDLKGPKV 4415
+ GL+G Q+P+ K+ K + ++GP++ V ++ + P V
Sbjct: 861 LPGA--------------LGLQG-----QVPAAKMGKGERVEGPEVAAGVREVGFRVPSV 901
Query: 4416 EVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKF-----KM 4470
E+ +P L P++E++ EG L + + V SKF +PKF K+
Sbjct: 902 EIVTPQL----PAVEIE-------------EGRLEMIETKVKPS-SKFSLPKFGLSGPKV 943
Query: 4471 PSFGMLSPGKSIEVSVD---VSAPKM----EADMSIPSMQGDLKTTDLRIQAPSADLEVQ 4523
G++ ++ V +S PK EA+ G L DL I S D +
Sbjct: 944 AKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLP 1003
Query: 4524 AGQV-----DLK-------LPEGHM-----------PEVAGLKGHL----PKVEMPSFKM 4556
+G+V DLK LP+ + P VA L+G +V+MP KM
Sbjct: 1004 SGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKLKM 1063
Query: 4557 PKVDL-KGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLS 4615
P L +G + +V+G + G KAE A V++ +P VE + GA+ EG
Sbjct: 1064 PSFGLARGKEAEVQGDRAS-PGEKAESTA--VQLKIPEVEL-------VTLGAQEEGR-- 1111
Query: 4616 LAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEG 4675
A VA + G K+ST+G VV EG
Sbjct: 1112 -AEGAVAVSGMQLSGLKVSTAG--------------------------------QVVTEG 1138
Query: 4676 DLHDPS-RDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTP---KDSLVPGAKSSIGL 4731
HD R LG+++ +V + F TP S VP A+ + G
Sbjct: 1139 --HDAGLRMPPLGISLPQVEL-------------TGFGEAGTPGQQAQSTVPSAEGTAGY 1183
Query: 4732 S------TIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDL-TGPHFESSIL 4784
T+ L ++ + EL E +MP V P LD+ ++
Sbjct: 1184 RVQVPQVTLSLPGAQVAGGEL----LVGEGVFKMPTVTV---PQLELDVGLSREAQAGEA 1236
Query: 4785 SPCEDVTLTKYQVTVPRAALAPELALEIPSGSQAD--IPLPKTECSTDLQPPEGVPTSQA 4842
+ E K RA + E A E P G++ + LP E S ++
Sbjct: 1237 ATGEGGLRLKLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG 1296
Query: 4843 ESHSG-------PLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSP 4895
E +G P ++ G K PK +P++ + ++ G+P
Sbjct: 1297 EGEAGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKL--RLPRVGFSQSEMVTGEGSP---- 1350
Query: 4896 LSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPL-- 4953
SP E + + G +G V + + AP +A SP+
Sbjct: 1351 -SPEEEEE---EEEEGSGEGASGRRGRVR-VRLPRVGLAAPSKASRGQEGDAAPKSPVRE 1405
Query: 4954 KMPKIKLPSFRWSPKKETG 4972
K PK + P SPK +G
Sbjct: 1406 KSPKFRFPRVSLSPKARSG 1424
Score = 154 bits (389), Expect = 2e-36
Identities = 324/1352 (23%), Positives = 542/1352 (40%), Gaps = 267/1352 (19%)
Query: 469 DTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLK 528
+ +G P R+++ L+ + A E + R + P R + +A AG
Sbjct: 173 EAVKGPVPAAPARRRLQLPRLRVREVA--EEAQAARLAAAAPPPRKAKVEAEVAAGARFT 230
Query: 529 GEEVEGAG-WMPGRE---PTTHAEAQGDEGDGEEG----LQRTRITEEQDKGREDTEGQI 580
+VE G +PG E P A + G L + E I
Sbjct: 231 APQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGI 290
Query: 581 RMPKFKIPSLGWSPSKHT-----------------------KTGREKATEDTEQGREGEA 617
++P+ ++P+L P+ T G + A E GEA
Sbjct: 291 QVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEA 350
Query: 618 TATADRREQRRTEE-GLKDKEDSDSMTNTTKIQLIHDEKRLKKEQI--------LTEKEV 668
A + + G + KE +++ K+ + E R+K ++ L E
Sbjct: 351 PEVALKMPRLSFPRFGARAKEVAEA-----KVAKVSPEARVKGPRLRMPTFGLSLLEPRP 405
Query: 669 ATKD---SKFKMPKFKMPL--FGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDL 723
A + SK K+P KMP G S P + +V PK +V L + +
Sbjct: 406 AAPEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKA-PEVKLPKVP---EAALP 461
Query: 724 SVQTPSADL-EVQDGQV---------DVKLPEGPLPEGASLKGHLPKVQR---PSLKMPK 770
V+ P +L +V + ++ +V+LPE LP+ + +K LPKV P +++P+
Sbjct: 462 EVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMK--LPKVPEMAVPEVRLPE 519
Query: 771 VDLKGPKLDLKGPKA-EVTAPDVKM------SLSSMEV----DVQAPRAKLDGARLEGDL 819
V L ++K PK E+ P+V++ +S M++ +V P +L +L
Sbjct: 520 VQLLKVS-EMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVP 578
Query: 820 SLADKEV-TAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKA 878
+ E+ K + K+P+ K+P V P DV P+V+ ++K
Sbjct: 579 EMKVPEMKLPKVPEMKLPEMKLPE--VQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKL 636
Query: 879 TDLSIQP------PSADL-EVQAGQV-DVKLPEGPVPEGAGPKVHLPKVEMP---SFKMP 927
++ + P L EVQ +V ++KLP+ +PE A P+V LP+V++P K+P
Sbjct: 637 PEVKLPKVPEMAVPDVHLPEVQLPKVPEMKLPK--MPEMAVPEVRLPEVQLPKVSEMKLP 694
Query: 928 KV------DLKGPQI------DVKGPKL---DLKGPKA-EVTAPD-----------GEVS 960
KV D+ P++ ++K P + ++K PK E+ PD E+
Sbjct: 695 KVPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIR 754
Query: 961 LPSMEV----DVQAQKA---KLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS-- 1011
LP M+V DV KA KL A + + + FKMPK MP G +
Sbjct: 755 LPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLGRAES 814
Query: 1012 -APGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLK------VQADQVDV 1064
+ GK +A +VS V P + G+ S+ S +L +Q
Sbjct: 815 PSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAA 874
Query: 1065 KLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQ---VDVKGPKLDLKSPKAEVTAPD 1121
K+ +G EG + + +V F++P V + PQ V+++ +L++ K + P
Sbjct: 875 KMGKGERVEGPEVAAGVREV---GFRVPSVEIVTPQLPAVEIEEGRLEMIETKVK---PS 928
Query: 1122 VEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRF--KMPKFKMPSFGASAPG 1179
+ SLP + G K+ A EG A + K S+F +PK ++ GA A
Sbjct: 929 SKFSLPKFGLS----GPKVAKAEAEG----AGRATKLKVSKFAISLPKARV---GAEAEA 977
Query: 1180 K-----SIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPP----------SADLEVHA 1224
K + ++D+S P++ D LPS + ++ DL + P D E
Sbjct: 978 KGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAE 1037
Query: 1225 GQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDLKGHKAEVT 1283
V LEG +G G+ G +V+MP LKMP L +G + EV+G + G KAE T
Sbjct: 1038 LVPGVAELEG---KGWGWDG---RVKMPKLKMPSFGLARGKEAEVQGDRAS-PGEKAEST 1090
Query: 1284 AHEVAVSLPSVEV-------DMQAPGA-KLDGAQLDG-DLSLADKDVTAKDSKFKMPKFK 1334
A V + +P VE+ + +A GA + G QL G +S A + VT +
Sbjct: 1091 A--VQLKIPEVELVTLGAQEEGRAEGAVAVSGMQLSGLKVSTAGQVVTEGHD----AGLR 1144
Query: 1335 MPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDV 1394
MP G+S P + + P +A ++PS +G T +Q P L L Q
Sbjct: 1145 MPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEG---TAGYRVQVPQVTLSLPGAQ--- 1198
Query: 1395 KLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEV 1454
+ G + G G+ FK+P V + E+D+ G + + + + +
Sbjct: 1199 -VAGGELLVGEGV-----------FKMPTVTVPQLELDV-GLSREAQAGEAATGEGGLRL 1245
Query: 1455 SLPSV----EVDVEAPGAKLDGGRLEEDMSLADKDLTTK--------------DSKFKMP 1496
LP++ V E + G +SL D +L+ ++ K+
Sbjct: 1246 KLPTLGARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKL- 1304
Query: 1497 KFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSM---QGDLKATDLSIQPPSADLEVQ 1553
K ++P FG+ + E +PK+ LP + Q ++ + S P + E +
Sbjct: 1305 KVRLPRFGLVRAKEGAEEGEKAKSPKLR----LPRVGFSQSEMVTGEGSPSPEEEEEEEE 1360
Query: 1554 AGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVT 1613
G G G G +V++ ++P+V L P +G + D PK V
Sbjct: 1361 EG------------SGEGASGRRGRVRV---RLPRVGLAAPSKASRGQEGD-AAPKSPVR 1404
Query: 1614 APDVKMSLSSMEVDVQAPRAKL-DGAQLEGDL 1644
K + + +P+A+ G Q EG L
Sbjct: 1405 EKSPKFRFPRVSL---SPKARSGSGDQEEGGL 1433
Score = 105 bits (261), Expect = 2e-21
Identities = 48/87 (55%), Positives = 67/87 (77%)
Query: 109 EATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFEN 168
E E+ ++TE + G SG +V GGG +GIFV+++ +DS AA+ +L+EGDQLLS VFFEN
Sbjct: 15 ELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFEN 74
Query: 169 IKYEDALKILQYSEPYKVQFKIRRQLP 195
KYEDAL++LQ +EPYKV F ++R +P
Sbjct: 75 FKYEDALRLLQCAEPYKVSFCLKRTVP 101
Score = 103 bits (257), Expect = 5e-21
Identities = 336/1476 (22%), Positives = 546/1476 (36%), Gaps = 292/1476 (19%)
Query: 4409 DLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKF 4468
++KGP+ +V N+ SL ++ PGA L LA DV +F PKF
Sbjct: 116 EIKGPRAKVAKLNIQ-SLSPVKKKKMVPGA------LGVPADLAPVDV-----EFSFPKF 163
Query: 4469 KMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQ-----GDLKTTDLRIQAP-----SA 4518
G+ K+ V V A + +P ++ + + L AP
Sbjct: 164 SRLRRGL----KAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKV 219
Query: 4519 DLEVQAG------QVDL---KLP--EGHMPEVAGLKG------------HLPKVEM---- 4551
+ EV AG QV+L +LP E +P+V+ K HLP + +
Sbjct: 220 EAEVAAGARFTAPQVELVGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPA 279
Query: 4552 -PSFKMPKVDLKGPQVDVKG----------PKLDLKGPKAEVMAPDVEVSLPSVETDVQA 4600
P+ + P V ++ PQV++ P L+ + V+ P ++V+ P+V D+
Sbjct: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339
Query: 4601 PGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIE------- 4653
PG+ ++ AR E +VA K + P+ E + KV+ S E
Sbjct: 340 PGAEVE-ARGEAP------EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLR 392
Query: 4654 ----GNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEV----GMDSKFKKLHF- 4704
G + + +VES + + PS +G++ EV G + K K
Sbjct: 393 MPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSL--GIGVSGPEVKVPKGPEVKLPKAPEV 450
Query: 4705 ---KVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPK 4761
KVP+ + + P+ L S + L +P L +V M++PK
Sbjct: 451 KLPKVPEAALPEVRLPEVELPK--VSEMKLPKVP--EMAVPEVRLPEVELPKVSEMKLPK 506
Query: 4762 VGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIP 4821
V P RL E +L E ++ VP L PE+ ++P S+ +P
Sbjct: 507 VPEMAVPEVRLP------EVQLLKVSEMKLPKVPEMAVPEVRL-PEV--QLPKVSEMKLP 557
Query: 4822 LPKTECSTDLQPPE----GVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQM 4877
+++ PE VP + P + + L ++ P+ PK VP+M
Sbjct: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLP--KVPEMKLPEMKLPEVQLPK----VPEM 611
Query: 4878 AVPEGDLHAAVGAPVMSPLSPGERV-QCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAP 4936
AVP D+H V P P ++ + LP +LP PE V + V
Sbjct: 612 AVP--DVHLP---EVQLPKVPEMKLPEMKLPEVKLPKV-------PEMAVPDVHLPEVQL 659
Query: 4937 GEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETG-PKVDPECSVEDSKLSLVLDKDEV 4995
+ P K + +P+++LP + E PKV PE +V D L EV
Sbjct: 660 PKVPEMKLP---KMPEMAVPEVRLPEVQLPKVSEMKLPKV-PEMAVPDVHLP------EV 709
Query: 4996 APQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASK-SGVSLPQRDVD--PSLSSA 5052
M +P + E P A+P + LP+++ K S + LP+ V P +
Sbjct: 710 QLPKVCEMKVPDMKLPEIKLPKVPEMAVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLP 769
Query: 5053 TAGGSFQDTEKASSDGGRGGLGATASATGSEGVNL--HRPQVHIPSLGFAKPDLRSS--K 5108
A E L AT A +EG+ P++ +P LG A+ R +
Sbjct: 770 KA------PEVKLPRAPEVQLKAT-KAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGE 822
Query: 5109 AKVEVS---------QPEAD---------LPLPKHDLSTEGDSRGCGL-GDVPVSQPCGE 5149
A EVS QPE D L LP +L G GL G VP ++
Sbjct: 823 AGAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPG---ALGLQGQVPAAKMGKG 879
Query: 5150 GIAPTPEDPL---QPSCRKPDAEVLTVESPEEEAM--------TKYSQESWFKMPKFRMP 5198
PE + R P E++T + P E TK S F +PKF +
Sbjct: 880 ERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLS 939
Query: 5199 SLRRSFRDRGGAG---KLEVAQ---TQAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPE 5252
+ + + GAG KL+V++ + A G EA AK + + A+ L +P+
Sbjct: 940 GPKVAKAEAEGAGRATKLKVSKFAISLPKARVGAEAEAKG----AGEAGLLPALDLSIPQ 995
Query: 5253 ADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLP----- 5307
+ K ++ DL G + L G+ G + +E + P L
Sbjct: 996 LSLDAHLPSGK--VEVAGADLKFKGPRFALPKFGVRGRDTEAAE--LVPGVAELEGKGWG 1051
Query: 5308 ----FQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEKWSSQ---PEGPLKLKAS 5360
+MP +++P + G+ E D AS +K E + Q PE L +
Sbjct: 1052 WDGRVKMPKLKMPSFGLARGKEAEVQ-----GDRASPGEKAESTAVQLKIPEVELVTLGA 1106
Query: 5361 STDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEANI 5420
+ ++ +V +V ++ L V D + P+ +
Sbjct: 1107 QEEGRAEGAV---------AVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVEL 1157
Query: 5421 DTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPISKVRVHIQGAQVESQEVTIH 5480
+PG S + + G G + + +V + + GAQV E+ +
Sbjct: 1158 TGFGEAGTPGQQAQSTVPSAEGTAGYR----------VQVPQVTLSLPGAQVAGGELLVG 1207
Query: 5481 SIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPEPHTQARVYTTMTQ 5540
V + ++VP+ + E E T G L++K+P +ARV
Sbjct: 1208 EGVF-KMPTVTVPQ-LELDVGLSREAQAGEAATGEGG---LRLKLPTLGARARV------ 1256
Query: 5541 HSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSSVNVLGQQTLTFEVPSGHQLA 5600
EG EE P PG + PD E+ S N Q E +GH+L
Sbjct: 1257 ---GGEGAEEQP----PGAERTFCLSLPDV----ELSPSGGNHAEYQVAEGEGEAGHKL- 1304
Query: 5601 DSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVDE 5660
+ P RA + E +K+ LP +GFS S
Sbjct: 1305 --------------------KVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMV 1344
Query: 5661 TGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAE 5720
TG S + + + + E E + R P++G ++P+K S+ ++G
Sbjct: 1345 TGEGSPSPEE-----EEEEEEEGSGEGASGRRGRVRVRLPRVGL-AAPSKASRG-QEGDA 1397
Query: 5721 LEEQKLQEETITFFDARESFSPE------EKEEGEL 5750
+ ++E++ F R S SP+ ++EEG L
Sbjct: 1398 APKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGL 1433
Score = 53.5 bits (127), Expect = 6e-06
Identities = 119/614 (19%), Positives = 228/614 (37%), Gaps = 129/614 (21%)
Query: 384 DREVMPAQSMPLPT-ELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQP 442
+ +V P+ LP L P++ + EG RA +L + + A++ K R
Sbjct: 922 ETKVKPSSKFSLPKFGLSGPKVAKAEA-EGAGRATKL-------KVSKFAISLPKARVGA 973
Query: 443 TPGMSREGEGEGLQSLEIGIARLSL-RDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKE 501
GE L +L++ I +LSL G ++ +++ + PKF
Sbjct: 974 EAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKF------- 1026
Query: 502 PERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQ 561
G++G + E A +PG
Sbjct: 1027 ------------------------GVRGRDTEAAELVPG--------------------- 1041
Query: 562 RTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATA 621
+ E + KG +G+++MPK K+PS G + K + ++A+ G + E+TA
Sbjct: 1042 ---VAELEGKGW-GWDGRVKMPKLKMPSFGLARGKEAEVQGDRAS----PGEKAESTAVQ 1093
Query: 622 DR-REQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKF 680
+ E G +++ ++ + +QL K Q++TE A
Sbjct: 1094 LKIPEVELVTLGAQEEGRAEGAVAVSGMQL-SGLKVSTAGQVVTEGHDA---------GL 1143
Query: 681 KMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVD 740
+MP G S P + + P +A ++ S +G +A VQ QV
Sbjct: 1144 RMPPLGISLPQVELTGFGEAGTPGQQAQSTVPSAEG------------TAGYRVQVPQVT 1191
Query: 741 VKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLK-GPKLDLKGPKAEVTAPDVKMSLSSM 799
+ LP + G L G + P++ +P+++L G + + +A +++ L ++
Sbjct: 1192 LSLPGAQVAGGELLVGE-GVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL 1250
Query: 800 ----EVDVQAPRAKLDGARLEGDLSLADKEVT---AKDSKFKMP----------KFKMPS 842
V + + GA LSL D E++ +++++ K ++P
Sbjct: 1251 GARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPR 1310
Query: 843 FGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLP 902
FG+ + E+ +PK+ + Q ++ + S P + E + G
Sbjct: 1311 FGLVRAKEGAEEGEKAKSPKLRLP-RVGFSQSEMVTGEGSPSPEEEEEEEEEGS------ 1363
Query: 903 EGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLP 962
EGA + +V ++P+V L P +G + D PK+ V + P
Sbjct: 1364 ----GEGASGRRGRVRV-----RLPRVGLAAPSKASRGQEGD-AAPKSPVREKSPKFRFP 1413
Query: 963 SMEVDVQAQKAKLD 976
+ + +A+ D
Sbjct: 1414 RVSLSPKARSGSGD 1427
>gi|13491172 periaxin isoform 1 [Homo sapiens]
Length = 147
Score = 105 bits (261), Expect = 2e-21
Identities = 48/87 (55%), Positives = 67/87 (77%)
Query: 109 EATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFEN 168
E E+ ++TE + G SG +V GGG +GIFV+++ +DS AA+ +L+EGDQLLS VFFEN
Sbjct: 15 ELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFEN 74
Query: 169 IKYEDALKILQYSEPYKVQFKIRRQLP 195
KYEDAL++LQ +EPYKV F ++R +P
Sbjct: 75 FKYEDALRLLQCAEPYKVSFCLKRTVP 101
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 83.6 bits (205), Expect = 5e-15
Identities = 218/1085 (20%), Positives = 395/1085 (36%), Gaps = 168/1085 (15%)
Query: 155 EGDQLLSTTVFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEWASSDAQH-GPQG 213
EG+ L V E K E+ L+ E +++ + Q+EE + + G +G
Sbjct: 1311 EGEGLQEEAVQLEETKTEEGLQ----EEGVQLEETKETEGEGQQEEEAQLEEIEETGGEG 1366
Query: 214 KEKEDTDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWPKFQSIKSKRGP 273
++E + + +E P L+G+ +E L + G +E S G
Sbjct: 1367 LQEEGVQLEE-VKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQE------LSEASSPDGK 1419
Query: 274 GPQRSHSSSEAYEPRDAHDVSPTSTD-TEAQLTVERQEQKAGPGSQRRRKFLNLRFRTGS 332
G Q E R + P + TE + P + R+ L
Sbjct: 1420 GSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEK 1479
Query: 333 GQGPSSTGQ------PGRGF---QSGVGRAGVLEELGPWGDSL---------EETGAATG 374
G + GQ P +G S V + L+ W L +A
Sbjct: 1480 PPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVA 1539
Query: 375 SRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETA-- 432
R QD +++ + L ++ RL + T +E R LE +
Sbjct: 1540 ELRARWGLQDNDLLDQMAAELQQDVAQ-RLQDSTKRELQKLQGRAGRMVLEPPREALTGE 1598
Query: 433 ----VAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRD----TTEGGTQIG------ 478
QR+ R + +S E ++L +G +L D +T G+Q+G
Sbjct: 1599 LLLQTQQRRHRLRGLRNLSAFSE----RTLGLGPLSFTLEDEPALSTALGSQLGEEAEGE 1654
Query: 479 ---PPE--IRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVE 533
P E +R +V + +PK + P +E +Q K G GE E
Sbjct: 1655 EFCPCEACVRKKVSPM-SPKATMGATRGPIKEAF------DLQQILQRKRGEHTDGEAAE 1707
Query: 534 GAGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWS 593
A +PT+ QG EG GL + +E ED EG R+ + K P LG +
Sbjct: 1708 VAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDE----GEDGEGSQRLNRDKDPKLGEA 1763
Query: 594 PSKHTKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHD 653
RE T ++ E +A ++ E + EG+ ++ ++ +
Sbjct: 1764 EGDAMAQEREGKTHNS------ETSAGSELGEAEQEGEGISERGETGGQGS--------- 1808
Query: 654 EKRLKKEQILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLS 713
E L + A D + A G++ S V AP+ E D
Sbjct: 1809 ----GHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQ--E 1862
Query: 714 MQGDLKTTDLSVQTPSADLEVQDGQVDVKLPEG-----PLPEGASLKGHLPKVQRPSLKM 768
+G+ + V+ P A+ E Q DV+ PE P EGA + Q + +
Sbjct: 1863 AEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESV 1922
Query: 769 PKVDLKGPKLDLKGPKAE-VTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVT 827
++ +G P++E A + + + E Q ++ E + ++V
Sbjct: 1923 EALETEGE----DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVE 1978
Query: 828 AKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPS 887
A + + + + A G++ +S DV AP+ E ++ + + ++ + QP S
Sbjct: 1979 ALEVEVETQE---------AEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS 2029
Query: 888 ADLEVQAGQVDVKLPEGPV-PEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLK 946
E Q + + + EG PE G ++
Sbjct: 2030 EGEEAQEVEGETQKTEGDAQPESDG---------------------------------VE 2056
Query: 947 GPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMP 1006
P+AE A + E + E + + +D EG+ + V A +++ + K +
Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE-- 2114
Query: 1007 SFGVSAP---GKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVD 1063
G+ AP G++ + AP+ E + S + + + QP S ++ Q + +
Sbjct: 2115 --GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEE 2172
Query: 1064 VKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKG-PKLD-LKSPKAEVTA-P 1120
+ PE G++ P+ E + + ++ P+ + + P+L+ +++P+AE A P
Sbjct: 2173 AQ------PELEGVEA--PEAEGEA-QPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP 2223
Query: 1121 DVE-VSLPSVEVDV--EAPGAKLDSARLEGELSLAD-KDVTAKDSRFKMPKFK---MPSF 1173
+ E V P E + E+ G + ++SL D + A +S +P+ + PS
Sbjct: 2224 EPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSP 2283
Query: 1174 GASAP 1178
G P
Sbjct: 2284 GGDTP 2288
Score = 67.4 bits (163), Expect = 4e-10
Identities = 100/489 (20%), Positives = 192/489 (39%), Gaps = 73/489 (14%)
Query: 3592 VRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVS 3651
+ P+ E V+AP+A+ DA EG+ +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 3652 APGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQV 3711
A G++ S DV P+ E +V S + + QP + ++ + + + PE +
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDE-PESEG 1937
Query: 3712 PEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEV 3771
E +E + E + +V ++ + + + + +V A +VEV E
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEV------IESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 3772 DVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAP 3831
+ Q +++ + EG++ A+++ + S GV A P
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPE------------SDGVEA------------QP 2027
Query: 3832 KVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQM 3891
K E + ++G+ + T+ QP S + + + + EG V E G + H P+ +
Sbjct: 2028 KSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG-EAH-PESED 2084
Query: 3892 PSFKMPKVDLKGPEIDIKGPKLDLKDPKVE-VTAPDVEVSLPSVEVDVEAPGAKLDGARL 3950
+ + + + ++ P+ + + K E + AP+ E +EAP A
Sbjct: 2085 VDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA------- 2137
Query: 3951 EGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGD 4010
EG+ + + A+D++ + + S G+ A EA P++E V P +G+
Sbjct: 2138 EGEAQPESEGVEAQDAE---GEAQPESEGIEAQEAEEEAQ-----PELEG-VEAPEAEGE 2188
Query: 4011 LKATDLSVQPPSADLEVQAGQVDVKLPEG-----PVPEGASLKGHLPKVQMPSFKMPKVD 4065
+ ++ P A+ E Q V+ PE P PEG + Q S + +
Sbjct: 2189 AQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGE 2248
Query: 4066 LKG-PQIDV 4073
KG PQ+ +
Sbjct: 2249 KKGSPQVSL 2257
Score = 66.2 bits (160), Expect = 9e-10
Identities = 93/427 (21%), Positives = 175/427 (40%), Gaps = 58/427 (13%)
Query: 2494 GVSAP---GKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVK 2550
G+ AP G++ S V AP EA+G +G+ + ++ P A+ E Q DV+
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAP--EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVE 1891
Query: 2551 LPEG-----PVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQ---------LDVKGPKLDLK 2596
PE P EGA + Q + + ++ +G + + + +
Sbjct: 1892 TPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAE 1951
Query: 2597 G---PKAEV-TAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPK 2652
G P++EV + + E DV+A +++ EG+ + V A +++ +M +
Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011
Query: 2653 FKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQV 2712
+ + +EA + K E + ++G+ + T+ QP S +E +
Sbjct: 2012 AEE---EAQPESDGVEA-----QPKSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062
Query: 2713 DVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAE-VTAPD 2771
+ + EG V E G + H P+ + + E + + V+ P + + KAE + AP+
Sbjct: 2063 EAQEAEGEVQEAEG-EAH-PESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 2772 VKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAP-GK 2830
+ ++AP A EG+ +G+ A+D++ G + P +
Sbjct: 2121 TEGEAQPESEGIEAPEA-------EGEAQPESEGVEAQDAE-----------GEAQPESE 2162
Query: 2831 SIEASVDVSELKVEADG-SFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGH---V 2886
IEA E + E +G P +G+ + I+ P A+ E Q V+ PE
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQ 2222
Query: 2887 PEGAGLK 2893
PE G++
Sbjct: 2223 PEPEGVE 2229
Score = 65.9 bits (159), Expect = 1e-09
Identities = 95/462 (20%), Positives = 175/462 (37%), Gaps = 72/462 (15%)
Query: 2272 VTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVS 2331
+ AP+ E V+AP A+ D EG+ +DV A +++
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAE-------------- 1880
Query: 2332 ALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPV 2391
G++ S DV + E +V S + + QP + +E ++ + + P
Sbjct: 1881 --GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA----LETEGEDEPE 1934
Query: 2392 PEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEV 2451
EGA + Q + + I+ + + + + DV A +VEV E
Sbjct: 1935 SEGAEAQEAEEAAQEAE---GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 2452 DVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAP 2511
+ + ++ EG++ A+++ + S GV A KS
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPE------------SDGVEAQPKSEGEEAQ---- 2035
Query: 2512 KVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQM 2571
E +G +GD + ++ P A+ E Q + +V+ EG + H P+ +
Sbjct: 2036 --EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG--------EAH-PESED 2084
Query: 2572 PSFKMPEMDLKGPQLDVKGPKLDLKGPKAE-VTAPDVEMSLSSMEVDVQAPRAKLDGARL 2630
+ E + + V+ P+ + + KAE + AP+ E ++AP A
Sbjct: 2085 VDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA------- 2137
Query: 2631 EGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEAD-MSLPSMQG 2689
EG+ +GV A+D++ + E IEA E + E + + P +G
Sbjct: 2138 EGEAQPESEGVEAQDAEGE----------AQPESEGIEAQEAEEEAQPELEGVEAPEAEG 2187
Query: 2690 DLKTTDISIQPPSAQLEVQAGQVDVKLPEGH---VPEGAGLK 2728
+ + I+ P A+ E Q V+ PE PE G++
Sbjct: 2188 EAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVE 2229
Score = 64.7 bits (156), Expect = 3e-09
Identities = 92/447 (20%), Positives = 179/447 (40%), Gaps = 54/447 (12%)
Query: 3322 APGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGH- 3380
A G++ S V AP+AE D +G+ + ++ P + E Q DV+ PE
Sbjct: 1840 AEGEAQPESEGVEAPEAEGDAQ--EAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEW 1897
Query: 3381 --VPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAE-VTVPDVEVSLP 3437
PE G + P+ E + P+ + ++ +G P++E + E +
Sbjct: 1898 EVQPESEGAEA--PEAEKEA--QPETE-SVEALETEGED----EPESEGAEAQEAEEAAQ 1948
Query: 3438 SVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLD 3497
E Q ++ E + +DV A + + + + A G + S D
Sbjct: 1949 EAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQE---------AEGEAQPESED 1999
Query: 3498 VSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPV-PEGAGL---- 3552
V AP+ E ++ + + ++ + QP S E Q V+ + + EG PE G+
Sbjct: 2000 VEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE 2059
Query: 3553 --------KGHLPKVEMPS-LKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVE-VSLP 3602
+G + + E + ++ VD + + + + ++ P+AE E + P
Sbjct: 2060 AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP 2119
Query: 3603 SVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVD 3662
E + Q ++A EG+ + V A+D++ + + + G + + +
Sbjct: 2120 ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA--------QPESEGIEAQEAEE 2171
Query: 3663 VSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQ-----VPEGAGL 3717
+ P++E V P +G+ + I+ P A+ + Q V+ PE + PEG
Sbjct: 2172 EAQPELEG-VEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET 2230
Query: 3718 KEHLPKVEMPSLKMPKVDLKG-PQVDI 3743
E + + S + + KG PQV +
Sbjct: 2231 PEAEGEAQPESEGETQGEKKGSPQVSL 2257
Score = 63.5 bits (153), Expect = 6e-09
Identities = 91/433 (21%), Positives = 177/433 (40%), Gaps = 71/433 (16%)
Query: 3427 VTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVS 3486
+ P+ E V+AP A+ D EG+ +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 3487 APGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPV 3546
A G + S DV P+ E +V S + + QP + +E ++ E + P
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA----LETEGEDEPE 1934
Query: 3547 PEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEV 3606
EGA + + +T P+ +V ++ +AE E + P E
Sbjct: 1935 SEGAEAQEAEEAAQEAEGQTQ------PESEV------IESQEAE------EEAQPESE- 1975
Query: 3607 DVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSA- 3665
DV+A + +++ EG+ +DV A +++ +M + A ++ S V A
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE---------AEEEAQPESDGVEAQ 2026
Query: 3666 PKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVE 3725
PK E + ++G+ + T+ QP S ++ + + + EG+V E G E P+ E
Sbjct: 2027 PKSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG--EAHPESE 2083
Query: 3726 MPSLKMPKVDLKGPQVDIKGPKLDLKVSKAE-VTAPDVE---------VSLPSVEVDVQA 3775
+ + + + ++ P+ + + KAE + AP+ E + P E + Q
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQP 2143
Query: 3776 PRAKLDSAQLEGDLSLADKDVTAKDSKFK-MPKFKMPSFGVSAP---GKSIEASVHVSAP 3831
+++ EG+ + + A++++ + P+ + GV AP G++ S + AP
Sbjct: 2144 ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE----GVEAPEAEGEAQPESEGIEAP 2199
Query: 3832 KVEADVSLPSMQG 3844
+ E + P ++G
Sbjct: 2200 EAEGEAQ-PELEG 2211
Score = 63.2 bits (152), Expect = 7e-09
Identities = 98/460 (21%), Positives = 181/460 (39%), Gaps = 74/460 (16%)
Query: 3757 VTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS 3816
+ AP+ E V+AP A+ D+ + EG+ +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 3817 APGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADL-TVQARQVDMKLLEGH 3875
A G++ S V P+ E +V S + + QP + + ++ D EG
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA 1938
Query: 3876 VPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVE 3935
+EA + Q + ++ + E + + D++ +VEV + E
Sbjct: 1939 EAQEAEEAAQEAEGQTQP-ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPES 1997
Query: 3936 VDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTA 3995
DVEAP A EG++ A+++ + S GV A
Sbjct: 1998 EDVEAPEA-------EGEMQEAEEEAQPE------------SDGVEA------------Q 2026
Query: 3996 PKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQ 4055
PK E + ++G+ + T+ QP S +E + + + EG V E A + H P+ +
Sbjct: 2027 PKSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE-AEGEAH-PESE 2083
Query: 4056 MPSFKMPKVDLKGPQIDVKGPKLDLKGPKAE-VTAPDVKMSLSSMEVDVQAPRAKLDGVQ 4114
+ + + + V+ P+ + + KAE + AP+ + ++AP A
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA------ 2137
Query: 4115 LEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQG 4174
EG+ + V A+D++ + + S G+ A EA ++ ++A P +G
Sbjct: 2138 -EGEAQPESEGVEAQDAE---GEAQPESEGIEAQEAEEEAQPELEGVEA------PEAEG 2187
Query: 4175 DLKTTDLSIQSPSADLEVQAGQVDVKLPEG-----PLPKG 4209
+ + I++P A+ E Q V+ PE P P+G
Sbjct: 2188 EAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEG 2227
Score = 61.6 bits (148), Expect = 2e-08
Identities = 102/486 (20%), Positives = 183/486 (37%), Gaps = 84/486 (17%)
Query: 1117 VTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGAS 1176
+ AP+ E VEAP A+ D+ EGE +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 1177 APGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGH- 1235
A G++ S DV P+ E +V P +G + P A+ E V+ LE
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQ-PESEG--------AEAPEAEKEAQPETESVEALETEG 1929
Query: 1236 --VPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPS 1293
PE G + + + + + +E + + + + +V A EV V
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAE-GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQE 1988
Query: 1294 VEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDL 1353
E + Q ++ + +G++ A+++ + S GV A
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPE------------SDGVEA----------- 2025
Query: 1354 SAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPK 1413
PK E + ++G+ + T+ QP S +E + + + EG V E G + H P+
Sbjct: 2026 -QPKSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG-EAH-PE 2081
Query: 1414 LQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVE-VTAPDVEVSLPSVEVDVEAPGAKLDG 1472
+ + + + + ++ P+ + + K E + AP+ E +EAP A+ +
Sbjct: 2082 SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEA 2141
Query: 1473 GRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVD---VSAPKVEAD--- 1526
E + D + + + S G+ A EA + V AP+ E +
Sbjct: 2142 QPESEGVEAQDAE----------GEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQP 2191
Query: 1527 ----VSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEG-----PVSEG--AGLKGH 1575
+ P +G+ + ++ P A+ E Q V+ PE P SEG G K
Sbjct: 2192 ESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKG 2251
Query: 1576 LPKVQM 1581
P+V +
Sbjct: 2252 SPQVSL 2257
Score = 61.2 bits (147), Expect = 3e-08
Identities = 102/465 (21%), Positives = 181/465 (38%), Gaps = 78/465 (16%)
Query: 2932 VTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS 2991
+ AP+ E VEAP A+ D EG+ +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 2992 APGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQ--AGQVDLKLPEG 3049
A G++ S DV P+ E EV P +G E P A+ E Q V+ EG
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQ-PESEG--------AEAPEAEKEAQPETESVEALETEG 1929
Query: 3050 H-VPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPG 3108
PE G + + + + + I+ + + + + DV A +VEV
Sbjct: 1930 EDEPESEGAEAQEAE-EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQE 1988
Query: 3109 MEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDV 3168
E + + ++ EG++ A+++ + S GV A KS
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPE------------SDGVEAQPKS----EGE 2032
Query: 3169 SAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPK 3228
A +VE + +GD + +E P A+ E Q + +V+ EG + H P+
Sbjct: 2033 EAQEVEGETQ--KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG--------EAH-PE 2081
Query: 3229 LQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMD-VTAPDVE-VSQPSMEVDVEAPGAKLD 3286
+ + + + + ++ P+ + + K + + AP+ E +QP E +EAP A
Sbjct: 2082 SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESE-GIEAPEA--- 2137
Query: 3287 GARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPS 3346
EG+ + V A+D++ + + + G Q + + + P+ E V P
Sbjct: 2138 ----EGEAQPESEGVEAQDAEGEA--------QPESEGIEAQEAEEEAQPELEG-VEAPE 2184
Query: 3347 MQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGH---VPEGAGLK 3388
+G+ + I+ P + E Q V+ PE PE G++
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVE 2229
Score = 60.5 bits (145), Expect = 5e-08
Identities = 91/423 (21%), Positives = 169/423 (39%), Gaps = 50/423 (11%)
Query: 1667 SFGVSAPGKSIEASVDVSEPKVEA-----DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQ 1721
S GV AP EA D E + EA DV P +G+ + +++P A+ EVQ
Sbjct: 1848 SEGVEAP----EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPES 1903
Query: 1722 VNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKG---PKAEVM 1778
+ PE E + ++ P+ + + + + +G P++EV+
Sbjct: 1904 EGAEAPEAE-KEAQPETESVEALETEGEDEPE-SEGAEAQEAEEAAQEAEGQTQPESEVI 1961
Query: 1779 -APDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSA 1837
+ + E DVEA ++++ EG+ +DV A +++ +M + + + S
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESD 2021
Query: 1838 PGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVP 1897
++ S A +VE E +GD + + P A+ Q EG+V
Sbjct: 2022 GVEAQPKSEGEEAQEVEGETQ--KTEGDAQPESDGVEAPEAEEEAQEA-------EGEVQ 2072
Query: 1898 EGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVE-VSLPSMEV 1956
E G + H D VD + + + + ++ P+AE A E + P E
Sbjct: 2073 EAEG-EAHPESED--------VDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123
Query: 1957 DVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVD---V 2013
+ Q + ++ EG+ + + A+D++ + + S G+ A EA + V
Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAE---GEAQPESEGIEAQEAEEEAQPELEGV 2180
Query: 2014 PAPKVEAD-------VSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGH---VPE 2063
AP+ E + + P +G+ + ++ P A+ + Q V+ PE PE
Sbjct: 2181 EAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPE 2240
Query: 2064 GAG 2066
G
Sbjct: 2241 SEG 2243
Score = 59.7 bits (143), Expect = 8e-08
Identities = 90/451 (19%), Positives = 174/451 (38%), Gaps = 73/451 (16%)
Query: 3922 VTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVS 3981
+ AP+ E VEAP A+ D EG+ +D+ A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 3982 APGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPV 4041
A G++ S DV P+ E +V S + + QP + +E ++ + + P
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA----LETEGEDEPE 1934
Query: 4042 PEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSMEV 4101
EGA + Q + P+ +V ++ +AE A + ++EV
Sbjct: 1935 SEGAEAQEAEEAAQEAEGQTQ------PESEV------IESQEAEEEAQPESEDVEALEV 1982
Query: 4102 DVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMP----SFGVSAPGKSMEASVD 4157
+V+ A EG+ +DV A +++ +M + + S GV A KS
Sbjct: 1983 EVETQEA-------EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSE----- 2030
Query: 4158 VSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLP 4217
E + + +GD + +++P A+ E Q + +V+ EG + H P
Sbjct: 2031 -GEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG--------EAH-P 2080
Query: 4218 KVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDS 4277
+ + + + + V+ P+ + + KA+ + P E + + +++
Sbjct: 2081 ESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE------GIEAPETEGEAQPESEGIEA 2134
Query: 4278 VRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSM 4337
EG+ + + A+D++ + + S G+ A EA ++ V P
Sbjct: 2135 PEAEGEAQPESEGVEAQDAEGEA---QPESEGIEAQEAEEEAQPELEG------VEAPEA 2185
Query: 4338 QGDLKTTHLSIQPPSADLEVQAGQEDVKLPE 4368
+G+ + I+ P A+ E Q E V+ PE
Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Score = 58.2 bits (139), Expect = 2e-07
Identities = 85/412 (20%), Positives = 157/412 (38%), Gaps = 72/412 (17%)
Query: 844 GVSAP---GKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVK 900
G+ AP G++ +S V AP+ E D +G+ + ++ P A+ E Q DV+
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAPEAEGDAQ--EAEGEAQPESEDVEAPEAEGEAQPESEDVE 1891
Query: 901 LPEG-----PVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAE-VTA 954
PE P EGA + + + + ++ +G P++E A
Sbjct: 1892 TPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED-----------EPESEGAEA 1940
Query: 955 PDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 1014
+ E + E Q + ++ E + +DV A + + + + A G
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQE---------AEG 1991
Query: 1015 KSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEG 1074
++ DV AP+ E G+++ + QP S ++ Q P+ E
Sbjct: 1992 EAQPESEDVEAPEAE---------GEMQEAEEEAQPESDGVEAQ--------PKSEGEEA 2034
Query: 1075 AGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVE 1134
++G K E + P+ D +++P+AE A + E + E +
Sbjct: 2035 QEVEGETQKTEGDA---------QPESD------GVEAPEAEEEAQEAEGEVQEAEGEAH 2079
Query: 1135 APGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAP---GKSIEASVDVSAP 1191
+D+ EGE + V A ++ + K + G AP G++ S + AP
Sbjct: 2080 PESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE----GIEAPETEGEAQPESEGIEAP 2135
Query: 1192 KVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVK-LLEG-HVPEGAG 1241
+ E + S + + + QP S +E + + + LEG PE G
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG 2187
Score = 58.2 bits (139), Expect = 2e-07
Identities = 98/486 (20%), Positives = 188/486 (38%), Gaps = 63/486 (12%)
Query: 4142 SFGVSAPGKSMEASVDVSELKAKA-----DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQ 4196
S GV AP EA D E + +A DV P +G+ + +++P A+ EVQ
Sbjct: 1848 SEGVEAP----EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPES 1903
Query: 4197 VDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPV 4256
+ PE K P+ + + + + + + +A+ T
Sbjct: 1904 EGAEAPEAE-------KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQP 1956
Query: 4257 VEVSLPSMEV---------DVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPS 4307
+ S E DVEA ++++ EG+ +D+ A +++ +M +
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE----- 2011
Query: 4308 FGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLP 4367
A ++ S V A ++G+ + T QP S +E +E+ +
Sbjct: 2012 ----AEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEA 2067
Query: 4368 EGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLP 4427
EG V E G + H P+ + + + + + V P+ + + K E + P
Sbjct: 2068 EGEVQEAEG-EAH-PESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE------GIEAP 2119
Query: 4428 SMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVD 4487
E + Q +++ EG+ + V A+D++ + P S G + + +
Sbjct: 2120 ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA----QPE----SEGIEAQEAEE 2171
Query: 4488 VSAPKMEADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGH---MPEVAGLKG 4544
+ P++E + P +G+ + I+AP A+ E Q ++ PE PE G++
Sbjct: 2172 EAQPELEG-VEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVE- 2229
Query: 4545 HLPKVEMPSFKMPKVDLKG-----PQVDVKGPKLDLKGPKAEVMAPDVEVSLPSV--ETD 4597
P+ E + + + +G PQV + + + + + D PS +T
Sbjct: 2230 -TPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288
Query: 4598 VQAPGS 4603
Q PGS
Sbjct: 2289 HQRPGS 2294
Score = 53.1 bits (126), Expect = 8e-06
Identities = 98/464 (21%), Positives = 176/464 (37%), Gaps = 82/464 (17%)
Query: 2107 MRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVS 2166
+ P+ E V+AP A+ D+ +G+ ++D+ +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 2167 APGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVK-VQAGQVDVKLLEGP 2225
A G++ S DV P+ E ++ S + + QP + V+ ++ D EG
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA 1938
Query: 2226 VPEEVGLKGHLPKLQ-MPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSV 2284
+E + Q P +V ++ + E + + D++ +VEV + E
Sbjct: 1939 EAQEAEEAAQEAEGQTQPESEV--IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPE 1996
Query: 2285 EVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVS 2344
DV+AP A EG+M A+++ + S GV A KS A
Sbjct: 1997 SEDVEAPEA-------EGEMQEAEEEAQPE------------SDGVEAQPKSEGEEAQ-- 2035
Query: 2345 ALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKL 2404
++G+ + T+ QP S +E + + + EG V E G + H P+
Sbjct: 2036 -----------EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG-EAH-PES 2082
Query: 2405 QMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTD-VMAPDVEVSQPSVEVDVEAPGAKLDGA 2463
+ + + + + V+ P+ + + K + + AP+ E +EAP A
Sbjct: 2083 EDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA----- 2137
Query: 2464 WLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVD---VSAPKVEADGSLS 2520
EG+ + V +D+ + + S G+ A EA + V AP+ E
Sbjct: 2138 --EGEAQPESEGVEAQDAE---GEAQPESEGIEAQEAEEEAQPELEGVEAPEAE------ 2186
Query: 2521 SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEG-----PVPEG 2559
G+ + I+ P A+ E Q V+ PE P PEG
Sbjct: 2187 ---GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEG 2227
Score = 50.1 bits (118), Expect = 7e-05
Identities = 85/417 (20%), Positives = 168/417 (40%), Gaps = 45/417 (10%)
Query: 1999 GVSAPGRSIEA---SVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVK 2055
G+ AP EA S V AP+ E D +G+ + ++ P A+ + Q DV+
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAPEAEGDAQ--EAEGEAQPESEDVEAPEAEGEAQPESEDVE 1891
Query: 2056 LPEGH---VPEGAGLKGHLPKVEMPSL-KMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPD 2111
PE PE G + P+ E + + V+ + + + + + E +
Sbjct: 1892 TPEAEWEVQPESEGAEA--PEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQE 1949
Query: 2112 VE-VSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGK 2170
E + P EV +++ A+ ++ D+ ++ T++++ + A G+
Sbjct: 1950 AEGQTQPESEV-IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGE 2008
Query: 2171 SIEASVDVSP--------PKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLL 2222
EA + P PK E + + ++G+ + T+ QP S V+ + + +
Sbjct: 2009 MQEAEEEAQPESDGVEAQPKSEGEEA-QEVEGETQKTEGDAQPESDGVEAPEAEEEAQEA 2067
Query: 2223 EGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVE-VSL 2281
EG V E G + H P+ + VD + E + + ++ P+ E A E +
Sbjct: 2068 EGEVQEAEG-EAH-PESE-------DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA 2118
Query: 2282 PSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASA 2341
P E + + ++ EG+ + V A+D++ + + S G+ A EA
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA---QPESEGIEAQEAEEEAQP 2175
Query: 2342 DVSALKV-EAD---------VSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPE 2388
++ ++ EA+ + P +G+ + V+ P A+ E Q V+ PE
Sbjct: 2176 ELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPE 2232
Score = 49.3 bits (116), Expect = 1e-04
Identities = 91/456 (19%), Positives = 181/456 (39%), Gaps = 74/456 (16%)
Query: 1777 VMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS 1836
+ AP+ E VEAP A+ D+ EG+ +DV A +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPE---------------- 1878
Query: 1837 APGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQ--AGQVDMKLPEG 1894
A G++ S DV P+ E EV P +G P A+ Q V+ EG
Sbjct: 1879 AEGEAQPESEDVETPEAEWEVQ-PESEG--------AEAPEAEKEAQPETESVEALETEG 1929
Query: 1895 Q-VPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPS 1953
+ PE G + + P+++V ++ +AE A + +
Sbjct: 1930 EDEPESEGAEAQ----EAEEAAQEAEGQTQPESEV------IESQEAEEEAQPESEDVEA 1979
Query: 1954 MEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDV 2013
+EV+V+ Q+A EG+ +D+ A +++ +M + + + +EA
Sbjct: 1980 LEVEVETQEA-------EGEAQPESEDVEAPEAEGEMQEAEEEA---QPESDGVEAQ--- 2026
Query: 2014 PAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPK 2073
PK E + ++G+ + T+ QP S ++ + + + EG V E G + H P+
Sbjct: 2027 --PKSEGE-EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG-EAH-PE 2081
Query: 2074 VEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSA 2133
E + + + + ++ P+ + + K E + P E + Q +++
Sbjct: 2082 SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE------GIEAPETEGEAQPESEGIEAP 2135
Query: 2134 HLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQ 2193
+G+ ++ + +D++ + + S G+ A EA P++E + P +
Sbjct: 2136 EAEGEAQPESEGVEAQDAE---GEAQPESEGIEAQEAEEEAQ-----PELEG-VEAPEAE 2186
Query: 2194 GDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEE 2229
G+ + I+ A+ + Q +++ +E P EE
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQP---ELEGVEAPEAEE 2219
Score = 47.8 bits (112), Expect = 3e-04
Identities = 69/340 (20%), Positives = 139/340 (40%), Gaps = 40/340 (11%)
Query: 4309 GVSAPGKSIEASLDVSALKV-EADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLP 4367
G+ AP EA + ++ EA+ +G+ + ++ P A+ E Q EDV+ P
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETP 1893
Query: 4368 EG-----PVHEGAGLKGHLPKLQMPSFKVPKVDLKG---PQID-VNVPKLDLKGPKVE-V 4417
E P EGA + Q + V ++ +G P+ + + + + E
Sbjct: 1894 EAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQ 1953
Query: 4418 TSPNLDV---------SLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKF 4468
T P +V + P E D++A ++++ EG+ +DV A +++ +M +
Sbjct: 1954 TQPESEVIESQEAEEEAQPESE-DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEA 2012
Query: 4469 KMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVD 4528
+ + ++ S A ++E + +GD + ++AP A+ E Q + +
Sbjct: 2013 EEEAQPESDGVEAQPKSEGEEAQEVEGETQ--KTEGDAQPESDGVEAPEAEEEAQEAEGE 2070
Query: 4529 LKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVE 4588
++ EG + H P+ E VD + + + + ++ P+AE A E
Sbjct: 2071 VQEAEG--------EAH-PESE-------DVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114
Query: 4589 -VSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSK 4627
+ P E + Q ++ EG+ E V +D++
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE 2154
Score = 41.6 bits (96), Expect = 0.023
Identities = 65/323 (20%), Positives = 126/323 (39%), Gaps = 34/323 (10%)
Query: 4348 IQPPSADLEVQAGQEDVKLPE--GPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNV 4405
I+ P A+ E Q E V+ PE G E G + Q S V + +G +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEG------EAQPESEDVEAPEAEG---EAQP 1885
Query: 4406 PKLDLKGPKVE--VTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKF 4463
D++ P+ E V + P E + Q +++ EG+ + A++++
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Query: 4464 KMPKFK---MPSFGMLSPGKSIEV----SVDVSAPKMEADMSIPSMQGDLKTTDLRIQAP 4516
+ + P ++ ++ E S DV A +E ++ +G+ + ++AP
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA--LEVEVETQEAEGEAQPESEDVEAP 2003
Query: 4517 SADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLK 4576
A+ E+Q + E PE G++ PK E + + + + + D + ++
Sbjct: 2004 EAEGEMQEAE------EEAQPESDGVEAQ-PKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056
Query: 4577 GPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDV-----AGKDSKFQGP 4631
P+AE A + E + E + +D EG+ E V G+ K +G
Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116
Query: 4632 KLSTSGFEWSSKKVSMSSSEIEG 4654
+ + E + + + E EG
Sbjct: 2117 EAPETEGEAQPESEGIEAPEAEG 2139
Score = 37.0 bits (84), Expect = 0.57
Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 499 EKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEE 558
E++ E +R S ++ + E EG G E E + +EG EE
Sbjct: 1277 ERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQ--EEAVQLEETKTEEGLQEE 1334
Query: 559 GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEAT 618
G+Q E + +G+++ E Q+ +I G + E+ E E G +GEA
Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLE----EIEETGGEGLQEEGVQLEEVKEGPEGGLQGEAL 1390
Query: 619 ATADRREQRRTEEGLKDK 636
E+ EEGL ++
Sbjct: 1391 ------EEGLKEEGLPEE 1402
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 76.3 bits (186), Expect = 8e-13
Identities = 385/1882 (20%), Positives = 689/1882 (36%), Gaps = 269/1882 (14%)
Query: 3417 KLDLKVPKAEVTVPDVEVSLPSVE-VDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKM 3475
K+ KVP+ + P + P +E ++ + R + + ++ +++K V K S+ +
Sbjct: 9164 KVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPV 9223
Query: 3476 PK----FKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLK-------ATDLSIQ 3524
+ K+P+ S E S + E V++ +Q ++ A ++
Sbjct: 9224 QEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVE 9283
Query: 3525 PPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLD 3584
PP E+ E+ P+P+ KVE P+ K P+V K + K +
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPK---------KVEPPAPKVPEVPKKPVPEEKKPVPVP 9334
Query: 3585 LKGPKAEVRVPDV-EVSLPSVEVDV------QAPKAKLDAGRL-----EGDLSLADKDVT 3632
K P A +VP+V + +P ++ V +AP AK+ + E + ++ +
Sbjct: 9335 KKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREES 9394
Query: 3633 AKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKT---TDLSIQ 3689
+ ++PK K+P R P K E PKV A P + +
Sbjct: 9395 PPPAVPEIPKKKVPEERKPVPRKEEEVP---PPPKVPALPKKPVPEEKVAVPVPVAKKAP 9451
Query: 3690 PPSADLKVQAGQMDVKLPEGQ-----VPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIK 3744
PP A++ + + + + VP+ + H +V + +G + +
Sbjct: 9452 PPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH--EVSAEEEWSYSEEEEGVSISVY 9509
Query: 3745 GPKLDLKVSKAEVTAPDV---------EVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKD 3795
+ + +AEVT +V E L + V+A A++ Q E + L K
Sbjct: 9510 REEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQ-EKKIVLKPK- 9567
Query: 3796 VTAKDSKFKMPKFKMPSFGVS-APGKSIEASV----HVSAPKVEADVSLPSMQGDLKTTD 3850
+ AK + P K+P P K + A V V PKV + P + +
Sbjct: 9568 IPAKIEE--PPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKV 9625
Query: 3851 LSIQ-PHSADLTVQARQV--DMKLLEGHVPEEAGLKGHLP---KVQMPSFKM----PKVD 3900
+ ++ P A +T + Q+ + K+L +EA K +P K +P K+ PK +
Sbjct: 9626 IKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKRE 9685
Query: 3901 LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD 3960
+ P + K +K+ KV + AP E P +V K LE + ++
Sbjct: 9686 EEPPAKVTEFRKRVVKEEKVSIEAPKRE---PQPIKEVTIMEEKERAYTLEEEAVSVQRE 9742
Query: 3961 MTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQP 4020
++ + ++ F P + + + + E + + +
Sbjct: 9743 EEYEEYE----EYDYKEFEEYEPTEEYDQYEEYEEREYER----------YEEHEEYITE 9788
Query: 4021 PSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL 4080
P + V+ +PE PVP K + P K+ K + ++ V PK L
Sbjct: 9789 PEKPIPVKP------VPEEPVPT---------KPKAPPAKVLKKAVPEEKVPVPIPK-KL 9832
Query: 4081 KGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKM 4140
K P +V K+ + + + R K + + + K V A++ K +
Sbjct: 9833 KPPPPKVPEEPKKVFEEKIRISI-TKREKEQVTEPAAKVPMKPKRVVAEE------KVPV 9885
Query: 4141 PSFGVSAPGKSMEA--SVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADL--EVQAGQ 4196
P V+ P + E ++ E+ + +V + ++ + I + E
Sbjct: 9886 PRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPV 9945
Query: 4197 VDVKLPEGPLPKGAGLKGHLP---KVQMPCLKMPKVALKGPQ-VDVKGPKLDLKGPKADV 4252
+ VK+PE P K +P K + P K+P+V K + V V PK + K P A V
Sbjct: 9946 IPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKE-KPPPAKV 10004
Query: 4253 ----MTPVVEVSLP-SMEVDVEAPGAKLDSVRLEGDLSLADKDMTAK-DSKFKMPKFKMP 4306
PV E +P + VEAP AK+ V + + +K + K + P K+P
Sbjct: 10005 PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKK---PVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 4307 SFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKL 4366
P K I + + + + P + + + + P + EV +E V
Sbjct: 10062 E----VPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEE-EVLFEEEIVPE 10116
Query: 4367 PEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSL 4426
E E L L +P+ + P+ + VP + P+ E P +V L
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPE-EEEVPPEEEYVPEEEEFVPEEEV-L 10174
Query: 4427 PSME--VDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEV 4484
P ++ V + AP ++ E + + K+ ++PK K+ ++ P + +
Sbjct: 10175 PEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPK-KVEEKRIILPKEEEVL 10233
Query: 4485 SVDVSAPKMEADMS---IPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAG 4541
V+V+ E +S IP ++ ++ AP EV + +PE P
Sbjct: 10234 PVEVTEEPEEEPISEEEIPEEPPSIE--EVEEVAPPRVPEV----IKKAVPEAPTPVPKK 10287
Query: 4542 LKGHLPKV--EMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQ 4599
++ KV ++P K+P K K P++ K P+ +V+ P E P+ V
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTV- 10346
Query: 4600 APGSMLDGARLEGDLSLA-HEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTF 4658
LE +S+A ++V K+ + V EI F
Sbjct: 10347 ----------LEEKVSVAFRQEVVVKE-------------RLELEVVEAEVEEIPEEEEF 10383
Query: 4659 HEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPK 4718
HE VE EG+ H+ + L V + + +K+H + + +
Sbjct: 10384 HE-------VEEYFEEGEFHEVEEF--IKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFE 10434
Query: 4719 DSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPH 4778
P I IP +V EP ++P+V P +
Sbjct: 10435 KPKAPPKGPEISEKIIPPKKPPT------KVVPRKEPPAKVPEV-----PKKIV------ 10477
Query: 4779 FESSILSPCED-VTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKT-ECSTDLQPPEG 4836
E + P E V TK +P + PE + +P + + P PK E ++ P +
Sbjct: 10478 VEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKK 10537
Query: 4837 VPTSQAESHSGPLNSMIPVSLGQV---SFPKFYKPK------FVFSVPQMAVPEGDLHAA 4887
VP + P + V V P+ PK V P+ VPE + AA
Sbjct: 10538 VPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAA 10597
Query: 4888 VG-----APVMSPLSPGERV---QCPLPSTQLPS-PGTCVSQGPEELVASLQTSVVAPG- 4937
PV P +P E V + P+P + P P T V + P+ V + P
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK 10657
Query: 4938 -EAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVD--PECSVEDSKLSLVLDKDE 4994
E+P + E + L+ P ++ P+ P+V P+ V + K V+ K
Sbjct: 10658 PESPPPEVFEEPEEVALEEPPAEVVE---EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP 10714
Query: 4995 VAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATA 5054
+LPP + E + P +P + K +A + V ++V P A
Sbjct: 10715 ---------ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 5055 GGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKVEVS 5114
K + V +P V +P R+ EV
Sbjct: 10766 KKPEVPPAKVPE-------------VPKKPVLEEKPAVPVPE--------RAESPPPEVY 10804
Query: 5115 QPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVLTVE 5174
+ ++ P+ +++ E + VPV++ E P P P +P P+ +V ++
Sbjct: 10805 EEPEEIA-PEEEIAPEEEK------PVPVAEE-EEPEVPPPAVPEEPKKIIPEKKVPVIK 10856
Query: 5175 SPEEEAMTKYSQESWFKMPKFR 5196
PE + E + PK +
Sbjct: 10857 KPEAPPPKEPEPEKVIEKPKLK 10878
Score = 64.7 bits (156), Expect = 3e-09
Identities = 263/1274 (20%), Positives = 472/1274 (37%), Gaps = 250/1274 (19%)
Query: 3375 KLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVT------ 3428
K PE VP K P ++P ++PK + +V + PK ++ P A+V
Sbjct: 9983 KKPEEKVPVLIPKKEKPPPAKVP--EVPKKPVPEEKVPVPVPK-KVEAPPAKVPEVPKKP 10039
Query: 3429 VPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPS------ 3482
VP+ +V +P+ + V+AP AK+ + L EK T K + P K+P
Sbjct: 10040 VPEKKVPVPAPK-KVEAPPAKVP--EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP 10096
Query: 3483 FGVSAPGRSIEASLDVSAPKVEA---DVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDV 3539
V+ P + P+ E + + + ++ + + P ++ + +V
Sbjct: 10097 VPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPP 10156
Query: 3540 ELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEV 3599
E E VPE + +P+ E+ PKV + P P++ K + +V +P E
Sbjct: 10157 E--EEYVPEE---EEFVPEEEVLPEVKPKVPVPAPV-----PEIKKKVTEKKVVIPKKEE 10206
Query: 3600 SLPSVEVDVQAPKAKLDAGR--LEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSM 3657
+ P+ +V PK K++ R L + + +VT + + + + ++P S+
Sbjct: 10207 APPAKVPEV--PK-KVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE-----EPPSI 10258
Query: 3658 EASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGL 3717
E +V+ P+V + K + P ++ ++ K+PE +VP
Sbjct: 10259 EEVEEVAPPRVPEVIK--------KAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVP--- 10307
Query: 3718 KEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPR 3777
+ K E P K+P+V K P+ + PK + T + +VS+ + V R
Sbjct: 10308 ---VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKER 10364
Query: 3778 AKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADV 3837
+L+ + E + +++ + F+ +F +E + + +VE +
Sbjct: 10365 LELEVVEAEVEEIPEEEEFHEVEEYFEEGEF-----------HEVEEFIKLEQHRVEEEH 10413
Query: 3838 SLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMP 3897
+ + H +A +V++ F+ P
Sbjct: 10414 RVEKV-------------HRVIEVFEAEEVEV------------------------FEKP 10436
Query: 3898 KVDLKGPEIDIK--GPKLDLKDPKVEVTAPDVEVSLPSV--EVDVEAPGAKLDGARLEGD 3953
K KGPEI K PK K P V + +P V ++ VE + R+
Sbjct: 10437 KAPPKGPEISEKIIPPK---KPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493
Query: 3954 L--SLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDL 4011
+ + K +P K P + P K EA +V P+ + V P + ++
Sbjct: 10494 KVPEVLPPKEVVPEKKVPVPPAKKPE---APPPKVPEAPKEV-VPEKKVPVP-PPKKPEV 10548
Query: 4012 KATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQI 4071
T + P +A E + + PE P PE PK +P K+P K P++
Sbjct: 10549 PPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE----VPEAPKEVVPEKKVPAAPPKKPEV 10604
Query: 4072 -DVKGPKLDLK-GPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAK 4129
VK P+ + P+ +V P K + P K+ V
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPKKP--------EVPPTKVPEV---------------- 10640
Query: 4130 DSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSAD 4189
K +P+ K+P + P K +V E + +++++ P A+
Sbjct: 10641 -PKVAVPEKKVPE---AIPPKPESPPPEVFE----------------EPEEVALEEPPAE 10680
Query: 4190 LEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQV-DVKGPKLDLKGP 4248
+ V+ PE P + PK +P K P V K P++ VK P++ P
Sbjct: 10681 V--------VEEPEPAAPPQVTVP---PKKPVPEKKAPAVVAKKPELPPVKVPEV----P 10725
Query: 4249 KADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSF 4308
K V V + +P EAP AK+ V E + + A K ++P K+P
Sbjct: 10726 KEVVPEKKVPLVVPKKP---EAPPAKVPEVPKE----VVPEKKVAVPKKPEVPPAKVP-- 10776
Query: 4309 GVSAPGKSIEASLDVSALKVEADVSLPSMQGDLK--TTHLSIQPPSADLEVQAGQEDVKL 4366
P K + + A+ P + + + I P A +E+ ++
Sbjct: 10777 --EVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834
Query: 4367 PEGPVHEGAGLKGHLPKLQMPSFKVPKV---DLKGPQIDVNVPKLDLKGPKVEVTSPNLD 4423
P V E K +P+ ++P K P+ P+ + PKL + P P D
Sbjct: 10835 PPPAVPEEP--KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKED 10892
Query: 4424 V--------SLPSMEV-------------DIQAPGAKLDSTRLEGDLSLADK-DVTAKDS 4461
V ++P +V ++ PG + +L + K +V K
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSV 10952
Query: 4462 KFKMPKFKMPSFGMLSPGKSIEVS----VDVSAPKMEADMSIPSMQGDLKTTDLRIQAPS 4517
K P+ + P + P K +V + PK ++ +P+ + + +I P+
Sbjct: 10953 LRKRPEEEEPK---VEPKKLEKVKKPAVPEPPPPKPVEEVEVPT----VTKRERKIPEPT 11005
Query: 4518 ADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVD-----LKGP-QVDVKGP 4571
E++ + L PE P+ E+ + K P V+ + P V V G
Sbjct: 11006 KVPEIKPA-IPLPAPEPKPK---------PEAEVKTIKPPPVEPEPTPIAAPVTVPVVGK 11055
Query: 4572 KLDLKGPKAEVMAP 4585
K + K PK E P
Sbjct: 11056 KAEAKAPKEEAAKP 11069
Score = 63.2 bits (152), Expect = 7e-09
Identities = 442/2132 (20%), Positives = 783/2132 (36%), Gaps = 364/2132 (17%)
Query: 1932 KLDLKGPKAEVTAPDVEVSLPSME-VDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKM 1990
K+ K P+ + P + P +E ++ +++ + + ++ ++ K + K S+ +
Sbjct: 9164 KVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPV 9223
Query: 1991 PK----FKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLK 2046
+ K+P+ S E + E V++P +Q ++ T + S +
Sbjct: 9224 QEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISK--R 9281
Query: 2047 VQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVE 2106
V+ +LPE PE KVE P+ K+P+V K + K + K+P
Sbjct: 9282 VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Query: 2107 MRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSF--G 2164
+VP+V P E + P AK K + P K+P G
Sbjct: 9342 PKVPEVP-KKPVPEEKIPVPVAK----------------------KKEAPPAKVPEVQKG 9378
Query: 2165 VSAPGK-SIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLE 2223
V K +I + SPP ++ + + K + + KV A L +
Sbjct: 9379 VVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPA------LPK 9432
Query: 2224 GPVPEEVGLKGHLP-----KLQMPSFKVPKVDLKGPEIDIKGPKLDLKDP-KVEVTAPDV 2277
PVPEE K +P K P +V K + + + KL P +VEVT +V
Sbjct: 9433 KPVPEE---KVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489
Query: 2278 EVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSI 2337
+ G + R E + +VT + + P+ ++ + + K +
Sbjct: 9490 SAE-EEWSYSEEEEGVSISVYREEEREEEEEAEVTEYE-VMEEPEEYVVEEKLHIISKRV 9547
Query: 2338 EAS-ADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAG 2396
EA A+V+ + + V P + ++ +PP A + ++ +PE VP
Sbjct: 9548 EAEPAEVTERQEKKIVLKPKIPAKIE------EPPPAKVPEAPKKI---VPEKKVPAPVP 9598
Query: 2397 LKGHLPKLQMPSF-KMPKVDLKGPQIDVKGPK-LDLKGPKTDVMAPDVEVSQPSVEVDVE 2454
K +P ++P K P + K P +K + L K + + E +V
Sbjct: 9599 KKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEA 9658
Query: 2455 APGAKLDGAWLEGDLSVADKDV-TTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKV 2513
P A++ E +V ++ V K R + P K+ F E V + APK
Sbjct: 9659 PPKARVPE---EPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVK---EEKVSIEAPKR 9712
Query: 2514 EAD--GSLSSMQGDLKATDLSIQPPSADLEVQAGQVD----------------------- 2548
E ++ M+ +A L + S E + + +
Sbjct: 9713 EPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYE 9772
Query: 2549 -------------VKLPEGPVPEGAGLKGHLP-KVQMPSFKMPEMDLKGPQLDVKGPKLD 2594
+ PE P+P + +P K + P K+ + + ++ V PK
Sbjct: 9773 EREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK-K 9831
Query: 2595 LKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDS-----KFK 2649
LK P +V ++ + + + R K + + K V A++ K
Sbjct: 9832 LKPPPPKVPEEPKKVFEEKIRISI-TKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV 9890
Query: 2650 MPKFKMPSFRVSAPGESI----EALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQL 2705
P ++P E + E + V E VE + + + T + + P +
Sbjct: 9891 APPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVV--PVIPV 9948
Query: 2706 EVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQ-IDVKGPNVDLKGPK 2764
+V ++P VPE K + P K+PEV K + + V P + K P
Sbjct: 9949 KVP------EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKE-KPPP 10001
Query: 2765 AEVTAPDV-KMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSF 2823
A+V P+V K + +V V P+ K++ A + K +P+ K+P
Sbjct: 10002 AKV--PEVPKKPVPEEKVPVPVPK-KVE----------APPAKVPEVPKKPVPEKKVP-- 10046
Query: 2824 GVSAPGKSIEASVDVSEL--KVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKL 2881
V AP K V E+ K+ + P+ + PP + + V V L
Sbjct: 10047 -VPAPKKVEAPPAKVPEVPKKLIPEEKKPTP----VPKKVEAPPPKVPKKREPVPVPVAL 10101
Query: 2882 P--------EGHVPEGAGLKGH---LPKVQ--MPSFK--MPKVDLKGPQIDVKGPKLDLK 2926
P E VPE L LP+ + +P + +P+ + P+ + P+ +
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYV 10161
Query: 2927 GPKAEVTAPDVEVSLPSV--EVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFK 2984
P+ E P+ EV LP V +V V AP ++ E + + K+ ++PK K
Sbjct: 10162 -PEEEEFVPEEEV-LPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPK-K 10218
Query: 2985 MPSFGVSAPGKSIEVSVDVSAPKVEAEVS---LPSMQGDLKTTDISIEPPSA-------- 3033
+ + P + + V+V+ E +S +P ++ + + PP
Sbjct: 10219 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVE-EVAPPRVPEVIKKAV 10277
Query: 3034 ---------QLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVK 3084
++E +V K+PE VP + K + P K+P+V +K P+ V
Sbjct: 10278 PEAPTPVPKKVEAPPAKVSKKIPEEKVPV------PVQKKEAPPAKVPEVPKKVPEKKVL 10331
Query: 3085 GPKLDLKGPKTDVTAPDVEVSQP-GMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKF 3143
PK + P T + +VS EV V+ RLE ++ A+ + ++ +F
Sbjct: 10332 VPKKEAVPPAKGRTVLEEKVSVAFRQEVVVK--------ERLELEVVEAEVEEIPEEEEF 10383
Query: 3144 KMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQG-----DLKNTDISIEP--P 3196
++ + +E + + +VE + + + + + ++ +P P
Sbjct: 10384 ----HEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAP 10439
Query: 3197 SAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRK-GPQIDIKGPKLDL 3255
E+ + K P V +P+ + P+ K+P+V +K + ++ P+
Sbjct: 10440 PKGPEISEKIIPPKKPPTKV---------VPRKEPPA-KVPEVPKKIVVEEKVRVPEEPR 10489
Query: 3256 KGP-KMDVTAPDVEVSQPSMEVDV------EAPGAKLDGARLEGDLSLADKDV-TAKDSK 3307
P K+ P EV P +V V EAP K+ A E + +K V K
Sbjct: 10490 VPPTKVPEVLPPKEV-VPEKKVPVPPAKKPEAPPPKVPEAPKE---VVPEKKVPVPPPKK 10545
Query: 3308 FKMPKFKMPSY-RASAPGKSIQASVDVSAPKAEA-DVSLPSMQGDLKTTDLSIQLPSVDL 3365
++P K+P +A+ P K + ++ PK E+ +P ++ P
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAI---PPKPESPPPEVPEAPKEVVPEKKVPAAPPKKP 10602
Query: 3366 EVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKA 3425
EV +V + P+ VPE K E+P K+P+V P+V + K+ +P
Sbjct: 10603 EVTPVKVP-EAPKEVVPEKKVPVPPPKKPEVPPTKVPEV----PKVAVPEKKVPEAIPPK 10657
Query: 3426 EVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGV 3485
+ P EV EV ++ P A++ +E A VT K +P+ K P+
Sbjct: 10658 PES-PPPEVFEEPEEVALEEPPAEV----VEEPEPAAPPQVTVPPKK-PVPEKKAPAVVA 10711
Query: 3486 SAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGP 3545
P V P+V +V + + L PP+ EV V + + P
Sbjct: 10712 KKPELP-----PVKVPEVPKEV-VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 3546 VPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDV----EVSL 3601
K E+P K P+V K P ++ K P + + +AE P+V E
Sbjct: 10766 -----------KKPEVPPAKVPEVP-KKPVLEEK-PAVPVP-ERAESPPPEVYEEPEEIA 10811
Query: 3602 PSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFR--VSAPGKSMEA 3659
P E+ AP+ + E + ++ K +P+ K+P + + P K E
Sbjct: 10812 PEEEI---APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 3660 SVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKE 3719
+ PK++ P PP D+K + Q+ +P+ +VPE + E
Sbjct: 10869 EKVIEKPKLKPRPPPPPP-----------APPKEDVKEKIFQLKA-IPKKKVPEKPQVPE 10916
Query: 3720 HLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAK 3779
KVE+ LK+P G K K+ P EV L SV
Sbjct: 10917 ---KVELTPLKVP-----------GGEKKVRKLLPERKPEPKEEVVLKSV---------- 10952
Query: 3780 LDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSL 3839
L ++ K K+ K K P+ P K +E + K E +
Sbjct: 10953 ---------LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPE 11003
Query: 3840 PSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKV 3899
P+ ++K +P A P+ ++ + K P V
Sbjct: 11004 PTKVPEIKPA--------------------------IPLPAPEPKPKPEAEVKTIKPPPV 11037
Query: 3900 D-----LKGP-EIDIKGPKLDLKDPKVEVTAP 3925
+ + P + + G K + K PK E P
Sbjct: 11038 EPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKP 11069
Score = 62.8 bits (151), Expect = 1e-08
Identities = 436/2124 (20%), Positives = 782/2124 (36%), Gaps = 306/2124 (14%)
Query: 942 KLDLKGPKAEVTAPDGEVSLPSME-VDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKM 1000
K+ K P+ + P + P +E ++ +++ + + + ++ K V K S+ +
Sbjct: 9164 KVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPV 9223
Query: 1001 PK----FKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLK 1056
+ K+P+ S + + S + E +++P +Q ++ T + I A + +
Sbjct: 9224 QEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEE-KIHVAISK-R 9281
Query: 1057 VQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAE 1116
V+ +LPE PE KVE P+ K+P+V K + K + K P A
Sbjct: 9282 VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Query: 1117 VTAPDV-EVSLPSVEVDV------EAPGAKLDSAR----LEGELSL-ADKDVTAKDSRFK 1164
P+V + +P ++ V EAP AK+ + E ++++ ++ + + +
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE 9401
Query: 1165 MPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKT---TDLSIQPPSADLE 1221
+PK K+P P K E PKV A P + + PP A++
Sbjct: 9402 IPKKKVPEERKPVPRKEEEVP---PPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVS 9458
Query: 1222 VHAGQVDVKL-----LEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLK 1276
+ + L VP+ H +V + +G + V + +
Sbjct: 9459 KKTVVEEKRFVAEEKLSFAVPQRVEVTRH--EVSAEEEWSYSEEEEGVSISVYREEEREE 9516
Query: 1277 GHKAEVTAHEVAVSLPS--VEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKM---P 1331
+AEVT +EV VE + +++ + K V K+ P
Sbjct: 9517 EEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPP 9576
Query: 1332 KFKMPSFGVS-APGKSIEASV----DLSAPKVEADMSLPSMQGDLKTTDLSIQPP----S 1382
K+P P K + A V + PKV + P + + + ++ P
Sbjct: 9577 PAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKV 9636
Query: 1383 TDLELQAGQLDVKL---------PEGPVPEGAGLKGHLPKLQMPSFKV----PKVDLKGP 1429
T+ +Q Q + L P+ VPE PK +P KV PK + + P
Sbjct: 9637 TERHMQITQEEKVLVAVTKKEAPPKARVPEE-------PKRAVPEEKVLKLKPKREEEPP 9689
Query: 1430 EIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTK 1489
+ K +K+ KV + AP E P +V K LEE+ ++
Sbjct: 9690 AKVTEFRKRVVKEEKVSIEAPKRE---PQPIKEVTIMEEKERAYTLEEEAVSVQRE---- 9742
Query: 1490 DSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSAD 1549
+ + ++ F P + + + + E + + I P
Sbjct: 9743 EEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYER----------YEEHEEYITEPEKP 9792
Query: 1550 LEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPK 1609
+ V+ +PE PV K + P K+ K + ++ V PK LK P
Sbjct: 9793 IPVK------PVPEEPVP---------TKPKAPPAKVLKKAVPEEKVPVPIPK-KLKPPP 9836
Query: 1610 VEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKM-PSF 1668
+V K+ + + + R K + + + K V A++ K +P+ ++ P
Sbjct: 9837 PKVPEEPKKVFEEKIRISI-TKREKEQVTEPAAKVPMKPKRVVAEE-KVPVPRKEVAPPV 9894
Query: 1669 GVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNV-KLP 1727
V K +E E +V V ++ + + + + + V V V ++P
Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVP 9954
Query: 1728 EGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQ-MDVKGPKLDLKGPKAEV------MAP 1780
P+PE K + P K+P+V K + + V PK + K P A+V P
Sbjct: 9955 RKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKE-KPPPAKVPEVPKKPVP 10013
Query: 1781 DVEVSLPSVEVDVEAPGAKLDSVRL----EGDLSL-ADKDVTAKDSKF-KMPKFKMPSFG 1834
+ +V +P V VEAP AK+ V E + + A K V A +K ++PK +P
Sbjct: 10014 EEKVPVP-VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEK 10072
Query: 1835 VSAP-GKSIEA---SVDVSAPKVEAEVSLPSMQGDLKTTDLCIP----LPSADLVVQAGQ 1886
P K +EA V V V+LP + L ++ +P LP + V+ +
Sbjct: 10073 KPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEI-VPEEEVLPEEEEVLPEEE 10131
Query: 1887 VDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPD 1946
+ E +PE + +V +P+ + P+ +V L PK V AP
Sbjct: 10132 EVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV----LPEVKPKVPVPAP- 10186
Query: 1947 VEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFK--MPSFGVSAPG 2004
+P ++ V +K + + + ++ + +PK + +P P
Sbjct: 10187 ----VPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE 10242
Query: 2005 RSIEASVDVP--APKVE--ADVSLPSMQGDL-KTTDLSIQPPSADLKVQTGQVDVKLPEG 2059
+ ++P P +E +V+ P + + K + P ++ +V K+PE
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE 10302
Query: 2060 HVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSM 2119
VP + K E P K+P+V K P+ + PK + P V + +VS+
Sbjct: 10303 KVPV------PVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFR 10356
Query: 2120 EVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVS 2179
+ V R +L+ + + ++ + F+ +F +E + +
Sbjct: 10357 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF-----------HEVEEFIKLE 10405
Query: 2180 PPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKL 2239
+VE + + + ++ + + K +A ++ E +P + +P+
Sbjct: 10406 QHRVEEEHRVEKVHRVIEV--FEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRK 10463
Query: 2240 QMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGAR 2299
+ P+ KVP+V PK + + KV V E +P +V P ++
Sbjct: 10464 EPPA-KVPEV-----------PKKIVVEEKVRVPE---EPRVPPTKVPEVLPPKEV---- 10504
Query: 2300 LEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLP-SMQ 2358
+ K +P K + K EA +V E V +P +
Sbjct: 10505 -------------VPEKKVPVPPAKKPE---APPPKVPEAPKEVVP---EKKVPVPPPKK 10545
Query: 2359 GDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKG 2418
++ T + P +A E + + PE P PE PK +P K+P K
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE----VPEAPKEVVPEKKVPAAPPKK 10601
Query: 2419 PQI-DVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVT 2477
P++ VK P + PK V V V P E P K+
Sbjct: 10602 PEVTPVKVP----EAPKEVVPEKKVPVPPPK---KPEVPPTKVP---------------- 10638
Query: 2478 TKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPS 2537
++PK V+ P K + ++ PK E+ + + A + +PP+
Sbjct: 10639 ------EVPK-------VAVPEKKVPEAI---PPKPESPPPEVFEEPEEVALE---EPPA 10679
Query: 2538 ADLE----VQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKL 2593
+E QV V P+ PVPE K ++P K+PE+ P+ V K+
Sbjct: 10680 EVVEEPEPAAPPQVTVP-PKKPVPEKKAPAVVAKKPELPPVKVPEV----PKEVVPEKKV 10734
Query: 2594 DLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKF 2653
L PK + AP ++ EV P K+ + V K + P
Sbjct: 10735 PLVVPK-KPEAPPAKVPEVPKEV---VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV 10790
Query: 2654 KMPSFRVSAPGESIEALVDVS---ELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAG 2710
+P S P E E +++ E+ E + +P + + + + PP+ E +
Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE----EPEVPPPAVPEEPKKI 10846
Query: 2711 QVDVKLPEGHVPEGAGLKGHLPK--LQMPSFK--MPEVDLKGPQIDVKGPNVDLKG-PKA 2765
+ K+P PE K P+ ++ P K P P+ DVK LK PK
Sbjct: 10847 IPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKK 10906
Query: 2766 EV-TAPDV--KMSLSSMEV-----------DVQAPRAKLDGARLEGDLSLADKGMTAKDS 2811
+V P V K+ L+ ++V + P K + L+ L + K
Sbjct: 10907 KVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK-EEVVLKSVLRKRPEEEEPKVE 10965
Query: 2812 KFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLE 2871
K+ K K P+ P K +E + K E P+ ++K I + P + +
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA-IPLPAPEPKPK 11024
Query: 2872 VQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAE 2931
+A +K P PE + V +P K + K P+ + PK +KG +
Sbjct: 11025 PEAEVKTIKPPPVE-PEPTPIAA---PVTVPVVG-KKAEAKAPKEEAAKPKGPIKGVPKK 11079
Query: 2932 VTAPDVEVSLPSVEVDVEAPRAKL 2955
+P +EA R KL
Sbjct: 11080 TPSP------------IEAERRKL 11091
Score = 59.3 bits (142), Expect = 1e-07
Identities = 278/1341 (20%), Positives = 498/1341 (37%), Gaps = 281/1341 (20%)
Query: 824 KEVTAKDSKFKMPKFK-MPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLS 882
K V + +PK K P V K E+ V V PK E
Sbjct: 9956 KPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKE------------------ 9997
Query: 883 IQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPK 942
+PP A + ++P+ PVPE P KVE P K+P+V P+ V K
Sbjct: 9998 -KPPPAKVP--------EVPKKPVPEEKVPVPVPKKVEAPPAKVPEV----PKKPVPEKK 10044
Query: 943 LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPK 1002
+ + PK +V AP +V ++ + +K + K V A K +PK
Sbjct: 10045 VPVPAPK-KVEAPPAKVPEVPKKLIPEEKKP-----------TPVPKKVEAPPPK--VPK 10090
Query: 1003 FKMP-SFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQ 1061
+ P V+ P + + P+ E LP + L + + P ++ + ++
Sbjct: 10091 KREPVPVPVALPQEEEVLFEEEIVPEEEV---LPEEEEVLPEEE-EVLPEEEEVLPEEEE 10146
Query: 1062 V-----DVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKS--PK 1114
+ +V E ++PE + +P+ E+ PKV + P ++K + K PK
Sbjct: 10147 IPPEEEEVPPEEEYVPEE---EEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPK 10203
Query: 1115 AEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFG 1174
E P +P V VE L E + +VT + + + ++P
Sbjct: 10204 KEEAPP---AKVPEVPKKVEEKRIILPK-----EEEVLPVEVTEEPEEEPISEEEIPE-- 10253
Query: 1175 ASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEG 1234
SIE +V+ P+V + K + P +E +V K+ E
Sbjct: 10254 ---EPPSIEEVEEVAPPRVPEVIK--------KAVPEAPTPVPKKVEAPPAKVSKKIPEE 10302
Query: 1235 HVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSV 1294
VP + K + P K+P+V K P+ +V PK + T E VS+
Sbjct: 10303 KVPVP------VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFR 10356
Query: 1295 EVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLS 1354
+ + +L+ + + + +++ + F+ +F +E + L
Sbjct: 10357 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH-----------EVEEFIKLE 10405
Query: 1355 APKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDV-KLPEGPVPEGAGLKGHL-P 1412
+VE + + + ++ +A +++V + P+ P P+G + + P
Sbjct: 10406 QHRVEEEHRVEKVHRVIEV-------------FEAEEVEVFEKPKAP-PKGPEISEKIIP 10451
Query: 1413 KLQMPSFKVPKVD--LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKL 1470
+ P+ VP+ + K PE+ PK + + KV V E +P +V P ++
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEV----PKKIVVEEKVRVPE---EPRVPPTKVPEVLPPKEV 10504
Query: 1471 DGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLP 1530
+ K +P K P + P K EA +V P+ + V
Sbjct: 10505 -----------------VPEKKVPVPPAKKPE---APPPKVPEAPKEV-VPEKKVPV--- 10540
Query: 1531 SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVD 1590
PP EV K+PE P K +P+ ++P PK +
Sbjct: 10541 --------------PPPKKPEVPP----TKVPEVP-------KAAVPEKKVPEAIPPKPE 10575
Query: 1591 LKGPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKA 1650
P++ + PK + KV AP K ++ ++V +AP+ ++ K
Sbjct: 10576 SPPPEVP-EAPKEVVPEKKVPA-APPKKPEVTPVKVP-EAPK----------EVVPEKKV 10622
Query: 1651 VTAKDSKFKMPKFKMPSFG-VSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQ 1709
K ++P K+P V+ P K + ++ PK E+ P + + +++++
Sbjct: 10623 PVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP---PKPES----PPPEVFEEPEEVALE 10675
Query: 1710 SPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQM-DVKGPKL 1768
P A++ V+ PE P PK +P K P V K P++ VK P++
Sbjct: 10676 EPPAEV--------VEEPEPAAPPQVTVP---PKKPVPEKKAPAVVAKKPELPPVKVPEV 10724
Query: 1769 DLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKF 1828
PK V V + +P EAP AK+ V E + + A K ++P
Sbjct: 10725 ----PKEVVPEKKVPLVVPK---KPEAPPAKVPEVPKE----VVPEKKVAVPKKPEVPPA 10773
Query: 1829 KMPSFG-----VSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQ 1883
K+P P + + P+V E + + ++ + P+P A+
Sbjct: 10774 KVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE-KPVPVAE---- 10828
Query: 1884 AGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKV---DLKGPQTDVKGAKLDLKGPKA 1940
+ + ++P VPE K +P+ +P K P+ P+ ++ KL + P
Sbjct: 10829 --EEEPEVPPPAVPEEP--KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP 10884
Query: 1941 EVTAPDVEV--------SLPSMEVDVQAQ---KAKLDGARLEGDLSLADK---------- 1979
P +V ++P +V + Q K +L ++ G K
Sbjct: 10885 PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK 10944
Query: 1980 -DMTAKDSKFKMPKFKMPSFGVSAPGRSIEASV-DVPAPKVEADVSLPSMQGDLKTTDLS 2037
++ K K P+ + P + + +V + P PK +V +P+ + +
Sbjct: 10945 EEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT----VTKRERK 11000
Query: 2038 IQPPSADLKVQTGQVDVKLPE--GHVPEGAGLKGHLPKVEMPSLKMPKVD-----LKGP- 2089
I P+ K+PE +P A P+ E+ ++K P V+ + P
Sbjct: 11001 IPEPT------------KVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPV 11048
Query: 2090 QVDIKGPKLDLKDPKVEMRVP 2110
V + G K + K PK E P
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKP 11069
Score = 58.9 bits (141), Expect = 1e-07
Identities = 260/1254 (20%), Positives = 463/1254 (36%), Gaps = 209/1254 (16%)
Query: 3045 KLPEGHVPEGAGLKGHLPKLQMPSFKMP-KVDRKGPQIDVKGPKLDLKGPKTDVTAPDVE 3103
K P VPE +PK +P K+P V +K K P++ PK V V
Sbjct: 9998 KPPPAKVPE-------VPKKPVPEEKVPVPVPKKVEAPPAKVPEV----PKKPVPEKKVP 10046
Query: 3104 VSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPS------FGVSA 3157
V P VEAP AK+ + L +K T K + P K+P V+
Sbjct: 10047 VPAPKK---VEAPPAKVP--EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVAL 10101
Query: 3158 PGKSIEVLVDVSAPKVEA----DLSLPSMQGDLKNTDISI----EPPSAQLEVQAGQVDV 3209
P + + + P+ E + LP + L + + E P + EV + V
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYV 10161
Query: 3210 KLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPDVEV 3269
E V E L PK+ +P+ +P++ +K + + PK + AP +V
Sbjct: 10162 PEEEEFVPEEEVLPEVKPKVPVPA-PVPEIKKKVTEKKVVIPKKE--------EAPPAKV 10212
Query: 3270 SQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQA 3329
+ +V+ + L + + +VT + + + + ++P SI+
Sbjct: 10213 PEVPKKVEEKR-------IILPKEEEVLPVEVTEEPEEEPISEEEIPE-----EPPSIEE 10260
Query: 3330 SVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKG 3389
+V+ P+ + + +P +E +V K+PE VP
Sbjct: 10261 VEEVAPPRVPEVIKKA-------VPEAPTPVPK-KVEAPPAKVSKKIPEEKVPVP----- 10307
Query: 3390 HLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRAK 3449
+ K E P K+P+V K P+ + PK + P TV + +VS+ + V R +
Sbjct: 10308 -VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLE 10366
Query: 3450 LDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSL 3509
L+ E + E++ + F+ +F +E + + +VE + +
Sbjct: 10367 LEVVEAEVEEIPEEEEFHEVEEYFEEGEF-----------HEVEEFIKLEQHRVEEEHRV 10415
Query: 3510 SSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGP--VPEGAGLKGHLPKVEMPSLKTP 3567
+ ++ + +VE+ E P P+G + + +P K P
Sbjct: 10416 EKVHRVIEVFEAE---------------EVEVFEKPKAPPKGPEISEKI----IPPKKPP 10456
Query: 3568 KVDLKGPQIDVKGPKLDLK-GPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSL 3626
+ + K P++ K + +VRVP+ P+ +V PK
Sbjct: 10457 TKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKE------------- 10503
Query: 3627 ADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDL 3686
+ K +P K P + P K EA +V P+ + V P + ++ T +
Sbjct: 10504 -----VVPEKKVPVPPAKKPE---APPPKVPEAPKEV-VPEKKVPVP-PPKKPEVPPTKV 10553
Query: 3687 SIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQV-DIKG 3745
P +A + + + PE PE PK +P K+P K P+V +K
Sbjct: 10554 PEVPKAAVPEKKVPEAIPPKPESPPPE----VPEAPKEVVPEKKVPAAPPKKPEVTPVKV 10609
Query: 3746 PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKM 3805
P+ +V P+ +V +P + + P K+ +++ +K K+
Sbjct: 10610 PEAPKEV------VPEKKVPVPPPK-KPEVPPTKVPEVP---KVAVPEK---------KV 10650
Query: 3806 PKFKMPSFGVSAPGKSIEASVHVSAPKVEADV---SLPSMQGDLKTTDLSIQPHSADLTV 3862
P+ +P S P + E V+ + A+V P+ + P V
Sbjct: 10651 PE-AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709
Query: 3863 QARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEV 3922
A++ ++ ++ VPE +PK +P K+P V K PE P + + EV
Sbjct: 10710 VAKKPELPPVK--VPE-------VPKEVVPEKKVPLVVPKKPE----APPAKVPEVPKEV 10756
Query: 3923 TAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSA 3982
P+ +V++P E P AK+ ++ K + P +P S
Sbjct: 10757 -VPEKKVAVPK---KPEVPPAKV-------------PEVPKKPVLEEKPAVPVPERAESP 10799
Query: 3983 PGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVP 4042
P + E ++ AP+ E + + V PP+ E + + K+P P
Sbjct: 10800 PPEVYEEPEEI-APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP 10858
Query: 4043 EGASLKGHLPK--VQMPSFK--MPKVDLKGPQIDVKGPKLDLKG-PKAEV-TAPDV--KM 4094
E K P+ ++ P K P P+ DVK LK PK +V P V K+
Sbjct: 10859 EAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Query: 4095 SLSSMEV-----------DVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSF 4143
L+ ++V + P K + V L+ L ++ K K+ K K P+
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPK-EEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAV 10977
Query: 4144 GVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPE 4203
P K +E + K + + P+ ++K + + +P + +A +K P
Sbjct: 10978 PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPP 11036
Query: 4204 -GPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPV 4256
P P +P V K K P+ + PK +KG +P+
Sbjct: 11037 VEPEPTPIAAPVTVPVVG------KKAEAKAPKEEAAKPKGPIKGVPKKTPSPI 11084
Score = 52.0 bits (123), Expect = 2e-05
Identities = 221/1017 (21%), Positives = 382/1017 (37%), Gaps = 178/1017 (17%)
Query: 655 KRLKKEQILTEKEVATKDSKFKMPKFKMPLFGASAPGK--SMEASVDVSAPKVEADVSLL 712
K++++++I+ KE + + P+ P + S+E +V+ P+V +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIK-- 10274
Query: 713 SMQGDLKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVD 772
K + +E +V K+PE +P K + P K+P+V
Sbjct: 10275 ------KAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKK------EAPPAKVPEVP 10322
Query: 773 LKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSK 832
K P+ + PK E P ++ +V V + + RLE ++ A+ E ++ +
Sbjct: 10323 KKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEE 10382
Query: 833 FKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEV 892
F ++ + +E+ + + +VE + + + ++ + EV
Sbjct: 10383 F----HEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAE--------EV 10430
Query: 893 QAGQVDVKLPEGP------VPEGAGPKVHLPKVEMPSFKMPKVDLK-GPQIDVKGPKLDL 945
+ + P+GP +P P +P+ E P+ K+P+V K + V+ P+
Sbjct: 10431 EVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPA-KVPEVPKKIVVEEKVRVPEEPR 10489
Query: 946 KGP-KAEVTAPDGEVSLPSMEVDV------QAQKAKLDGAWLEGDLSLADKDV-TAKDSK 997
P K P EV +P +V V +A K+ A E + +K V K
Sbjct: 10490 VPPTKVPEVLPPKEV-VPEKKVPVPPAKKPEAPPPKVPEAPKE---VVPEKKVPVPPPKK 10545
Query: 998 FKMPKFKMPSFGVSA-PGKSIKALV--DVSAPKVEADLSLPSMQGDLKTTDL-SIQPAST 1053
++P K+P +A P K + + +P E + + + K +P T
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 1054 DLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSP 1113
+KV +V +PE +P K +P ++P ++PKVA+ +V P P
Sbjct: 10606 PVKVPEAPKEV-VPEKKVPVPPPKKPEVPPTKVP--EVPKVAVPEKKVPEAIP------P 10656
Query: 1114 KAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSF 1173
K E +P EV EV +E P A++ +E A VT + +P+ K P+
Sbjct: 10657 KPE--SPPPEVFEEPEEVALEEPPAEV----VEEPEPAAPPQVTVPPKK-PVPEKKAPAV 10709
Query: 1174 GASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLE 1233
A P V P+V +V +P + L PP+ EV V K +
Sbjct: 10710 VAKKP-----ELPPVKVPEVPKEV-VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVA 10763
Query: 1234 GHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPS 1293
VP+ K ++P K+P+V PK + K V E A S P
Sbjct: 10764 --VPK---------KPEVPPAKVPEV-----------PKKPVLEEKPAVPVPERAESPPP 10801
Query: 1294 ---VEVDMQAPGAKLDGAQLDGDLSLADKD-------VTAKDSKFKMPKFKMPSF--GVS 1341
E + AP ++ + + + +A+++ ++ K +P+ K+P +
Sbjct: 10802 EVYEEPEEIAPEEEI-APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEA 10860
Query: 1342 APGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPV 1401
P K E + PK++ P PP D++ + QL +P+ V
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPP-----------APPKEDVKEKIFQLKA-IPKKKV 10908
Query: 1402 PEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEV 1461
PE K Q+P KV LK P + K KL L + K E P EV L SV
Sbjct: 10909 PE---------KPQVPE-KVELTPLKVPGGEKKVRKL-LPERKPE---PKEEVVLKSV-- 10952
Query: 1462 DVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAP 1521
L EE+ + K K+ K K P+ P K +E +
Sbjct: 10953 --------LRKRPEEEEPKVEPK---------KLEKVKKPAVPEPPPPKPVEEVEVPTVT 10995
Query: 1522 KVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQM 1581
K E + P+ ++K + + PE A +K ++
Sbjct: 10996 KRERKIPEPTKVPEIKPA-----------------IPLPAPEPKPKPEAEVK----TIKP 11034
Query: 1582 PSFKMPKVDLKGP-QIDVKGPKLDLKGPKVEVTAP--DVKMSLSSMEVDVQAPRAKL 1635
P + + P + V G K + K PK E P +K ++A R KL
Sbjct: 11035 PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKL 11091
Score = 44.3 bits (103), Expect = 0.004
Identities = 115/539 (21%), Positives = 196/539 (36%), Gaps = 84/539 (15%)
Query: 5151 IAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMP-SLRRSFRD--R 5207
+ P PE+P+ + P A+VL PEE+ ++ K P ++P ++ F + R
Sbjct: 9795 VKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKK--LKPPPPKVPEEPKKVFEEKIR 9852
Query: 5208 GGAGKLEVAQTQAPAA-TGGEAAAKVKEFLVSGSNVEAAMSLQLPEA----DAEVTASES 5262
K E Q PAA + V E V E A +++PE + E A E
Sbjct: 9853 ISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEE 9912
Query: 5263 KSSTDILRCDLDSTGLKLHLSTAGMTGDE-LSTSEVRI-HPSKGPLPFQMPGMRLP-ETQ 5319
+ T + ++ +H +T +E + V++ + P+P + + +P + +
Sbjct: 9913 EVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKE 9972
Query: 5320 VLPGEIDETPLSKPGHDLASMEDKTEK--WSSQPEGPLKLKASSTDMPSQISVVNVDQLW 5377
P ++ E P KP + + K EK + PE P K +P + V V +
Sbjct: 9973 APPAKVPEVP-KKPEEKVPVLIPKKEKPPPAKVPEVPKK------PVPEEKVPVPVPK-- 10023
Query: 5378 EDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASIL 5437
V+ P VP P E V +P ++V+ P A + K P
Sbjct: 10024 -----KVEAPPAKVPEVP-KKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIP-------- 10069
Query: 5438 KAGAGVPGEQPVDLNLPLEAPP--ISKVR--VHIQGAQVESQEVTIHSIVTPEFVDLSVP 5493
++P + +EAPP + K R V + A + +EV + PE L
Sbjct: 10070 ------EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEE 10123
Query: 5494 RTFSTQ-----------IVRESEIPTSEIQTP---------------SYGFSLLKVKIPE 5527
+ + E EIP E + P +K K+P
Sbjct: 10124 EEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPV 10183
Query: 5528 PHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSSV------ 5581
P + +T+ EEAP P V + + + E++ V
Sbjct: 10184 PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243
Query: 5582 NVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESK 5640
+ ++ + E PS ++ + P I + P EA TP+ + AP K K
Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVP----EAPTPVPKKVEAPPAKVSKK 10298
Score = 36.6 bits (83), Expect = 0.75
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 15/114 (13%)
Query: 853 EDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGP 912
E+ V V+ P+V+ ++ A ++PP E LPE P PE P
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPE---------LPEKPAPEEVAP 9302
Query: 913 KVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEV 966
KVE P+ K+P+V P+ V K + PK E AP +P V
Sbjct: 9303 VPIPKKVEPPAPKVPEV----PKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPV 9352
Score = 35.0 bits (79), Expect = 2.2
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 34/115 (29%)
Query: 603 EKATEDTEQGREGEATATADRREQRRTEEGL------------KDKEDSDSMTNTTKIQL 650
EK E++E+ R + +RRTEEG K E + + TK +L
Sbjct: 1988 EKVPEESEELRS---------KFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDEL 2038
Query: 651 IHDEKRLKKEQILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKV 705
+H K L +E EK+ ++ K +P FK P K +E S + APK+
Sbjct: 2039 LHWTKELTEE----EKKALAEEGKITIPTFK--------PDK-IELSPSMEAPKI 2080
Score = 33.9 bits (76), Expect = 4.8
Identities = 96/410 (23%), Positives = 146/410 (35%), Gaps = 79/410 (19%)
Query: 4807 ELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVS----- 4861
E+ALE P + P P + P + VP +A + + PV + +V
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP 10730
Query: 4862 -------FPKFYK--PKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPL----PS 4908
PK + P V VP+ VPE + A P + P E + P+ P+
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV-AVPKKPEVPPAKVPEVPKKPVLEEKPA 10789
Query: 4909 TQLP----SPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPL---KMPKIKLP 4961
+P SP V + PEE +AP E E A E K P+ + P++ P
Sbjct: 10790 VPVPERAESPPPEVYEEPEE---------IAPEE---EIAPEEEKPVPVAEEEEPEVPPP 10837
Query: 4962 SFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGF 5021
+ PK K+ PE V V+ K E P + E+ K R P
Sbjct: 10838 AVPEEPK-----KIIPEKKVP------VIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP 10886
Query: 5022 AMPK----------LALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRG 5071
A PK A+PK K + PQ L+ G + K +
Sbjct: 10887 APPKEDVKEKIFQLKAIPKKKVPEK----PQVPEKVELTPLKVPGGEKKVRKLLPE---- 10938
Query: 5072 GLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKVEVSQPEADLPLPKHDLS--T 5129
+ V RP+ P + +P K V +P P+ + ++ T
Sbjct: 10939 RKPEPKEEVVLKSVLRKRPEEEEPKV---EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT 10995
Query: 5130 EGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESPEEE 5179
+ + + VP +P AP P+ KP+AEV T++ P E
Sbjct: 10996 KRERKIPEPTKVPEIKPAIPLPAPEPKP-------KPEAEVKTIKPPPVE 11038
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 66.2 bits (160), Expect = 9e-10
Identities = 108/508 (21%), Positives = 182/508 (35%), Gaps = 58/508 (11%)
Query: 206 DAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQ--------RE 257
+A+ GP+G+ DG E + E D+ER + GRG + E
Sbjct: 646 EAEDGPEGR-------GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 258 RLSWPKF---QSIKSKRGPGPQRSHSSSEAYEPRDAH-DVSPTSTDTEAQLTVERQEQKA 313
+ W K + + +R G Q+ + + H + D E + E + ++
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Query: 314 GPGSQ---RRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDSLEETG 370
G G + R K G + G+ +G + G G EE G+ EE G
Sbjct: 759 GEGEEVEGEREK------EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812
Query: 371 AATGSRREE-RAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQA- 428
G EE + E++ E + G+ EG +EG G+ EG+
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGE--------GEEEEGEGEEEEG-------EGEEEEGEGK 857
Query: 429 --QETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRV 486
+E + + + G E EGEG + E G + G + G E
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 487 HDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTH 546
+ K + E E E E + G+ + + + EE EG G G
Sbjct: 917 GEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 547 AEAQGDEGDGE-EGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKA 605
E +G+E +GE EG + E +++G + EG+ + + + G +
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 606 TEDTEQG----REGEATATADRREQRRTEEGL-----KDKEDSDSMTNTTKIQLIHDEKR 656
E E+G +EGE RE+ EEG +++ + K+ I +
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Query: 657 LKKEQILTEKEVATKDSKFKMPKFKMPL 684
K + +K V K + KMP+
Sbjct: 1097 YGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124
Score = 53.9 bits (128), Expect = 5e-06
Identities = 93/438 (21%), Positives = 159/438 (36%), Gaps = 43/438 (9%)
Query: 143 KDSSAAKLFNLREGDQLLSTTVFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEW 202
KD ++ EG++ L+ E K D + Q Q + +++ +EE
Sbjct: 679 KDKGRGEMERPGEGEKELAEK---EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH 735
Query: 203 ASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWP 262
+ + G +E+E+ +G E + +EG+ ++E K G++ + E
Sbjct: 736 GEGEEEEGD--REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 263 KFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDTEAQLTVERQEQKAGPGSQRRRK 322
+ G G ++ + +V + E + E++ G G + +
Sbjct: 794 GEGEEEETEGRGEEKEEGGEV-----EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 323 FLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDSLEETGAATGSRREERAE 382
G G+G G+ G G + G G EE G+ EE G G E E
Sbjct: 849 GEE---EEGEGKGEEE-GEEGEGEEEGEEGEGEGEEEEGEGEG-EEEGEGEGEEEEGEGE 903
Query: 383 QDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQ-ETAVAQRKPRAQ 441
+ E G+ EG +E G G+ EG+ + E + +
Sbjct: 904 GEEEGEGE---------GEEEEGEGKGEEEG-EEGEGEGEEEEGEGEGEDGEGEGEEEEG 953
Query: 442 PTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKE 501
G EGEGEG + EG + G E + + + E E
Sbjct: 954 EWEGEEEEGEGEG-------------EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 502 PERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQ 561
E E G+ ++ G ++GEE EG G E E + EG+GEE +
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGE-VEGEEGEGEG--EEEEGEEEGEEREKEGEGEEN-R 1056
Query: 562 RTRITEEQDKGREDTEGQ 579
R R EE+++G+ G+
Sbjct: 1057 RNREEEEEEEGKYQETGE 1074
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 62.4 bits (150), Expect = 1e-08
Identities = 214/1021 (20%), Positives = 342/1021 (33%), Gaps = 161/1021 (15%)
Query: 4708 KVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGF 4767
+V+ T TP ++ P +S+ ++ P++SSE + V S P K +
Sbjct: 2796 EVTSMPTSTPSETSTP--LTSMPVNHTPVASSEAGTLSTTPVDT-STPVTTSTKASSS-- 2850
Query: 4768 PSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLP---K 4824
P++ + P +S S LT V+ A + L S + D +P
Sbjct: 2851 PTTAEGIVVPISTASEGS----TLLTSIPVSTTPVASSEASTL---STTPVDTSIPVTTS 2903
Query: 4825 TECSTDLQPPEG--VPTSQAESHSGPLNSM----IPVSLGQVSFPKFYKPKFVFSVPQMA 4878
TE S+ EG +P S S PL S+ +PV+ + S V A
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSA 2963
Query: 4879 VPEGDLHAAVGAPVMSPLS-PGERVQCPLPSTQLPSPGTCVSQGP--EELVASLQTSVVA 4935
A G + P+S PGER + PL S + + S+ A T V
Sbjct: 2964 EASSSPTTAEGTSM--PISTPGER-RTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTT 3020
Query: 4936 PGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDS----KLSLVLD 4991
EA S EG G P+ P P T P PE S + S V+
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT-PVAIPEASTLSTTPVDSNSPVVT 3079
Query: 4992 KDEVA--PQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVDPSL 5049
EV+ P A +P E + P +P P ++ S +S D +
Sbjct: 3080 STEVSSSPTPAEGTSMPISTYSE---GSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV 3136
Query: 5050 SSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIP---SLGFAKPDLRS 5106
+++T S T + +S ++T SEG P ++P L + D
Sbjct: 3137 TTSTEAHSSPTTSEGTS---------MPTSTPSEGST---PLTYMPVSTMLVVSSEDSTL 3184
Query: 5107 SKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPS-CRK 5165
S V+ S P + EG S +P S P EG+ P P+ +
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTS-------IPTSTP-SEGMTPLTSVPVSNTPVAS 3236
Query: 5166 PDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQTQAPAATG 5225
+A +L+ + S E+ P S+ S G T P +T
Sbjct: 3237 SEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST-----PLTSMPVSTT 3291
Query: 5226 GEAAAKVKEFLVSGSNV--------EAAMSLQLPEADAEVTASESKSSTDILRCDLDSTG 5277
A+++ + ++ +A+ S + + + T++ S+ ST + +T
Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP 3351
Query: 5278 L-KLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPL-SKPGH 5335
+ ST T + ST V P G +P + G TPL S P
Sbjct: 3352 VVSSEASTLSTTPVDTSTP-VTTSTEASLSPTTAEGTSIPTSSPSEGT---TPLASMPVS 3407
Query: 5336 DLASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFS 5395
+ + S+ P L +ST+ S ++ L + P ++P +
Sbjct: 3408 TTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLST 3467
Query: 5396 FPAPSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPL 5455
P SSE T + P ++ SP + + G P+ N+P+
Sbjct: 3468 TPVASSEASTLSTTPVDTSTPVTT--SSPTNSSPTTAEVTSMPTSTAGEGSTPLT-NMPV 3524
Query: 5456 EAPPISKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPS 5515
P++ + + + + V ++ VT S P T ++ T + TPS
Sbjct: 3525 STTPVASS----EASTLSTTPVDSNTFVTSSSQASSSPATL--------QVTTMRMSTPS 3572
Query: 5516 YGFSLLKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFE 5575
G S L TTM S T + EA +TP VD
Sbjct: 3573 EGSSSL--------------TTMLLSS-TYVTSSEASTPSTPSVDR-------------- 3603
Query: 5576 MISSSVNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKD 5635
S+ V Q S S P E++ P E +TPL
Sbjct: 3604 --STPVTTSTQ---------------SNSTPTPPEVITLPMSTPSEVSTPLT-------- 3638
Query: 5636 KPESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAG 5695
+P S ++ E G S V S P+ T + P+
Sbjct: 3639 ------------IMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPI 3686
Query: 5696 W 5696
W
Sbjct: 3687 W 3687
Score = 49.3 bits (116), Expect = 1e-04
Identities = 236/1193 (19%), Positives = 383/1193 (32%), Gaps = 159/1193 (13%)
Query: 4590 SLPSVETDVQAPGSML-DGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMS 4648
S P+ D+ P S +G+ L + ++ VA ++ LST+ + +S V+
Sbjct: 2495 SSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS----TLSTTPVDSNSPVVT-- 2548
Query: 4649 SSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVPK 4708
S+EI + T E TS + S EG S + + +P
Sbjct: 2549 STEISSSATSAEGTS---MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPV 2605
Query: 4709 VSFSSTK----TPKDSLVP--------GAKSSIGLSTIPLSSSECSSFELQQV------- 4749
+ + T T KD+ +P + +SI +ST+P++SSE S+ V
Sbjct: 2606 TTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVT 2665
Query: 4750 ---SACSEPSMQMPKVGFAGFPSSR-LDLTGPHFESSILSPCEDVTLTKYQV-------- 4797
S P+ P R LT +++L+ E TL+ V
Sbjct: 2666 TSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTT 2725
Query: 4798 -----TVPRAALAPELALEIPSGSQ--------ADIPLPKTECST------DLQPPEGVP 4838
+ P A + + PS + +P+ +E ST D P
Sbjct: 2726 SAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTS 2785
Query: 4839 T------SQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPV 4892
T + AE S P ++ S S P + P ++ D V
Sbjct: 2786 TEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTST 2845
Query: 4893 MSPLSP--GERVQCPLPS--------TQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSE 4942
+ SP E + P+ + T +P T V+ +++ P +E
Sbjct: 2846 KASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTE 2905
Query: 4943 DADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKLSLV-LDKDEVAPQSAI 5001
+ MP I PS +P P E S LS +D SA
Sbjct: 2906 GSSSPTTAEGTSMP-ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964
Query: 5002 HMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDT 5061
P +G + PG + L M S V+ + + T+ T
Sbjct: 2965 ASSSPTTAEGTSMPISTPG--ERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTST 3022
Query: 5062 EKASSDGGRGGLGATASATGSEG------VNLHRPQVHIPSLGFAKPDLRSSKAKVEVSQ 5115
E +SS G G S T SEG + + V IP S + V S
Sbjct: 3023 EASSSPTTAEGTGIPIS-TPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTST 3081
Query: 5116 PEADLPLPKHDLS------TEGDS--RGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPD 5167
+ P P S +EG + G + PV+ ++ TP D P +
Sbjct: 3082 EVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTE 3141
Query: 5168 AEVLTVESPEEEAMTKYSQESWFKMPKFRMP-SLRRSFRDRGGAGKLEVAQTQAPAATGG 5226
A S T E P MP S T P T
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEG--STPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTST 3199
Query: 5227 EAAAKVKEFLVSGSNVEAAMSLQ-------LPEADAEVTASESK--SSTDILRCDLDSTG 5277
EA + G+++ + + +P ++ V +SE+ S+T + DS
Sbjct: 3200 EATSST---TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV-----DS-- 3249
Query: 5278 LKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDL 5337
L+T+ T+E P+ P P +P + + + LS D
Sbjct: 3250 -NTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADT 3308
Query: 5338 ASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFP 5397
++ + SS P P+ A T MP+ L S T P
Sbjct: 3309 STPVTTYSQASSSP--PI---ADGTSMPTSTYSEGSTPLTNMSFSTT------------P 3351
Query: 5398 APSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEA 5457
SSE T + P A + G +P P + PL +
Sbjct: 3352 VVSSEASTLSTTPVDTSTPVTTSTEASLSPTTA--------EGTSIPTSSPSEGTTPLAS 3403
Query: 5458 PPISKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYG 5517
P+S V E ++ + + V S + S I + +PTS S
Sbjct: 3404 MPVSTTPV----VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTP 3459
Query: 5518 FSLLKVK-IPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEM 5576
S++ + P ++A +T + T T +P ++P ++ GE
Sbjct: 3460 LSIMPLSTTPVASSEASTLSTTPVDTSTPV-TTSSPTNSSPTTAEVTSMPTSTAGE---- 3514
Query: 5577 ISSSVNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDK 5636
S + T V S S P + F SQ +++P + +
Sbjct: 3515 --GSTPLTNMPVSTTPVASSEA---STLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMS 3569
Query: 5637 PESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPK 5689
S+ S L L + + +S E S V RS P+ T ++ P+
Sbjct: 3570 TPSEGSSSLTTMLLSSTYVTS-SEASTPSTPSVDRSTPVTTSTQSNSTPTPPE 3621
Score = 48.9 bits (115), Expect = 1e-04
Identities = 212/1021 (20%), Positives = 335/1021 (32%), Gaps = 166/1021 (16%)
Query: 4713 STKTPKDSLVPGAKSSIGLSTIPLSSSECSSFEL------QQVSACSEPSMQMPKVGFAG 4766
+T TP + P +S+ +ST P++SSE S+ QV+ +E S P
Sbjct: 443 ATSTPSEGSTP--LTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNS 500
Query: 4767 FPSSRLDLTGPHFESSILSPCEDVT-LTKYQVTVPRAALAPELALEIPSGSQADIPLPKT 4825
P+S +P E T LT V+ A + L + +
Sbjct: 501 MPTS--------------TPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSS 546
Query: 4826 ECSTDLQPPEG--VPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGD 4883
E S+ PEG +PTS S PL +M PVS V + S + +
Sbjct: 547 EASSSSTTPEGTSIPTSTPSEGSTPLTNM-PVSTRLVVSSE-------ASTTSTTPADSN 598
Query: 4884 LHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSED 4943
+ S + E +P++ GT ++ S+ T++VA EA +
Sbjct: 599 TFVTTSSEASSSSTTAEGTS--MPTSTYSERGTTITS------MSVSTTLVASSEASTLS 650
Query: 4944 ADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSK--LSLVLDKDEVAPQSAI 5001
+P+ S G + E S S+ ++ VA A
Sbjct: 651 TTPVDSNTPVTTS----TEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706
Query: 5002 HMDLPPERDGEKGRSTKPGFAMPKLA----LPKMKASKSGVSLPQRDVDPSLSSATAGGS 5057
+ P ++ + P A +P S+ L V +L +++ +
Sbjct: 707 TLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAST 766
Query: 5058 FQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKV-EVSQP 5116
T +S A+ S T +EG ++ + PS G P L S + V+ P
Sbjct: 767 LSTTPLDTSTHITTSTEASCSPTTTEGTSM---PISTPSEG--SPLLTSIPVSITPVTSP 821
Query: 5117 EADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTP-EDPLQPSCRKPDAEVLTVES 5175
EA +T DS PV+ +PTP E P+ +
Sbjct: 822 EASTL-----STTPVDSNS------PVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSM 870
Query: 5176 PEEEAMTKYSQESWFK-MPKFRMPSLRRSFRDRGGAGKLEVAQTQAPAATGGEAAAKVKE 5234
P + S S P + S R E T P +T GE + +
Sbjct: 871 PVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSE--GTSMPTSTPGEGSTPL-- 926
Query: 5235 FLVSGSNVEAAMSLQLPEADAEVTASESK--SSTDILRCDLDSTGLKLHLSTAGMTGDEL 5292
+P++ V +SE++ S+T + +T + S G +
Sbjct: 927 -------------TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSI 973
Query: 5293 STSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEKWSSQPE 5352
TS PS+G P P + L + + LS D ++ T +S P
Sbjct: 974 PTST----PSEGTTPL----TSTPVSHTLVANSEASTLSTTPVD-SNTPLTTSTEASSPP 1024
Query: 5353 GPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVRE 5412
+ + T PS+ S P +P + SSE T +
Sbjct: 1025 PTAEGTSMPTSTPSEGST----------------PLTRMPVSTTMVASSETSTLSTTPAD 1068
Query: 5413 VQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPISKVRVHIQGAQV 5472
P A +S G +P + + PL + P+S V V
Sbjct: 1069 TSTPVTTYSQAS--------SSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLV------V 1114
Query: 5473 ESQEVTIHSIVTPEFVDLSVPRTFSTQ------IVRESEIPTSEIQTPSYGFSLLKVKIP 5526
S+ T+ + TP VD S+P T ST+ + IPTS PS G +
Sbjct: 1115 SSEASTLST--TP--VDTSIPVTTSTEASSSPTTAEGTSIPTS---PPSEGTT------- 1160
Query: 5527 EPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSSVNVLGQ 5586
P V TT+ S + T S P T E M +S+ +
Sbjct: 1161 -PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPG--ER 1217
Query: 5587 QTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATT-------PLADEGRAPKDKPES 5639
T +P H + E + + P D S TT P EG + S
Sbjct: 1218 STPLTSMPVRH---TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTS 1274
Query: 5640 KKSGLLW-----FWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKA 5694
+ S LL L +S++ T VD+K V S + + P +P
Sbjct: 1275 EGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSE 1334
Query: 5695 G 5695
G
Sbjct: 1335 G 1335
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 52.4 bits (124), Expect = 1e-05
Identities = 72/282 (25%), Positives = 116/282 (41%), Gaps = 39/282 (13%)
Query: 49 RPRPQGSSPVYEYTTEAADFGLQEDAPGRQGSAGRR-RSWWKRDSGDSRTFFRMSRPEAV 107
RP P+ PV + ++ D + + GR G RR W RD SR R +
Sbjct: 118 RPDPE---PVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRR 174
Query: 108 QEA-------TEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLL 160
A T+VTL + G + IFVK++ +DS AA+ N++EGD +L
Sbjct: 175 SVASSQPAKPTKVTLVKSRKNEEYGLRLASH----IFVKEISQDSLAARDGNIQEGDVVL 230
Query: 161 STT-VFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDT 219
EN+ DA +++ S+ K++ ++R A SD+ H E++D
Sbjct: 231 KINGTVTENMSLTDAKTLIERSKG-KLKMVVQRDERATLLNVPDLSDSIHSANASERDDI 289
Query: 220 DVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWPKFQSIKSKRGP--GPQR 277
+ ++L D PR R R ++ S P S S + P G R
Sbjct: 290 --------SEIQSLASDHSGRSHDRPPR--RSRSRSPDQRSEPSDHSRHSPQQPSNGSLR 339
Query: 278 SHSSSEAYEP-------RDAHDVSPTSTDTEAQLTVERQEQK 312
S +P + A D +P + + ++TVER E++
Sbjct: 340 SRDEERISKPGAVSTPVKHADDHTPKTVE---EVTVERNEKQ 378
Score = 42.4 bits (98), Expect = 0.014
Identities = 28/55 (50%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 125 GYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLS-TTVFFENIKYEDALKIL 178
G + GG D GIFV VL+DS AAK L EGDQ+L V F NI E+A+ L
Sbjct: 434 GLRLAGGNDVGIFVAGVLEDSPAAK-EGLEEGDQILRVNNVDFTNIIREEAVLFL 487
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 52.4 bits (124), Expect = 1e-05
Identities = 72/282 (25%), Positives = 116/282 (41%), Gaps = 39/282 (13%)
Query: 49 RPRPQGSSPVYEYTTEAADFGLQEDAPGRQGSAGRR-RSWWKRDSGDSRTFFRMSRPEAV 107
RP P+ PV + ++ D + + GR G RR W RD SR R +
Sbjct: 118 RPDPE---PVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRR 174
Query: 108 QEA-------TEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLL 160
A T+VTL + G + IFVK++ +DS AA+ N++EGD +L
Sbjct: 175 SVASSQPAKPTKVTLVKSRKNEEYGLRLASH----IFVKEISQDSLAARDGNIQEGDVVL 230
Query: 161 STT-VFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDT 219
EN+ DA +++ S+ K++ ++R A SD+ H E++D
Sbjct: 231 KINGTVTENMSLTDAKTLIERSKG-KLKMVVQRDERATLLNVPDLSDSIHSANASERDDI 289
Query: 220 DVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWPKFQSIKSKRGP--GPQR 277
+ ++L D PR R R ++ S P S S + P G R
Sbjct: 290 --------SEIQSLASDHSGRSHDRPPR--RSRSRSPDQRSEPSDHSRHSPQQPSNGSLR 339
Query: 278 SHSSSEAYEP-------RDAHDVSPTSTDTEAQLTVERQEQK 312
S +P + A D +P + + ++TVER E++
Sbjct: 340 SRDEERISKPGAVSTPVKHADDHTPKTVE---EVTVERNEKQ 378
Score = 42.4 bits (98), Expect = 0.014
Identities = 28/55 (50%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 125 GYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLS-TTVFFENIKYEDALKIL 178
G + GG D GIFV VL+DS AAK L EGDQ+L V F NI E+A+ L
Sbjct: 434 GLRLAGGNDVGIFVAGVLEDSPAAK-EGLEEGDQILRVNNVDFTNIIREEAVLFL 487
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 52.0 bits (123), Expect = 2e-05
Identities = 243/1125 (21%), Positives = 369/1125 (32%), Gaps = 192/1125 (17%)
Query: 440 AQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGP--PEIRVRVHDLKTPKFAFS 497
A P PG GEGE + + LS TEG + + D + +A +
Sbjct: 340 ADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEA 399
Query: 498 TEK-----EPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGD 552
++ EP + L K ++ S GL+ ++ W P T D
Sbjct: 400 DDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQD-GTVSWAVEAAPQT-----SD 453
Query: 553 EGDGEEGLQRTRITEEQDKGREDTE-----GQIRMPKFKIPSLGWSPSKHTKTGREKATE 607
G +++ Q+ E TE GQ +L +P E AT
Sbjct: 454 RG--------AYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQV----EVATR 501
Query: 608 DTEQGREGEATATADRRE-----QRRTEEGLKDKEDSDSMT--------NTTKIQLIHDE 654
T Q E E +TA + + ++EG+ + +S+T T + L D
Sbjct: 502 VTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDS 561
Query: 655 -KRLKKEQILT----EKEVATKDSKFKMPK--FKMPLFGASAPGKSMEASVDVSAPKVEA 707
+ LK+E L K VA + K +P A P ++ + SAPK A
Sbjct: 562 PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA 621
Query: 708 DVSLLSMQGD--LKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPS 765
+++S Q + L SV TP L+ D +L P P A+ + +
Sbjct: 622 AATIVSQQAEEGLTLPQDSVMTPPLPLQ------DTELSSAPKPVAAATL--VSQQAEEG 673
Query: 766 LKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKE 825
L +P+ P L L+ + DLS A K
Sbjct: 674 LTLPQDSAMTPPLPLQ----------------------------------DTDLSSAPKP 699
Query: 826 VTAKD--SKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKAT---D 880
V A S+ +P P ++D+ SAPK A +L S Q + T D
Sbjct: 700 VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 759
Query: 881 LSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVH--------LPK--VEMPSFKMPKVD 930
++ PP L +Q D L P P A V LP+ P + D
Sbjct: 760 SAMTPP---LPLQ----DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812
Query: 931 LKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEV-DVQAQKAKLDGAWLEGDLSLADK 989
L V + + + +T P P + + D A A A++
Sbjct: 813 LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 872
Query: 990 DVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQ 1049
+T P + +S+ K + A VS + E L+LP Q T L +Q
Sbjct: 873 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVS-QQAEEGLTLP--QDSAMTAPLPLQ 929
Query: 1050 PASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLD 1109
T + + V P+ E G P M ++ + P + K L
Sbjct: 930 --DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALP 987
Query: 1110 LKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFK 1169
T P+ +L V+ D P A+ G A +D DS M
Sbjct: 988 --------TVPE-PAALDQVQQDDPQPAAE------AGTPWAAQEDA---DSTLGMEALS 1029
Query: 1170 MPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVD- 1228
+P A G E + +S P EA + + GD D P LEV Q
Sbjct: 1030 LPE---PASGAGEEIAEALSRPGREACLEARAHTGDGAKPD---SPQKETLEVENQQEGG 1083
Query: 1229 -VKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEV 1287
L + H P A G P P+V Q + P + +G + T
Sbjct: 1084 LKPLAQEHGPRSA-LGGAREVPDAPPAACPEVS----QARLLSPAREERGLSGKSTPEPT 1138
Query: 1288 AVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPK-----------FKMP 1336
S + E + + GA D D + P+ ++P
Sbjct: 1139 LPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1198
Query: 1337 S------------FGVSAPGKSIEASV--DLSAPKVEADMSLPSMQGDLKTTDLSIQPPS 1382
S P ++ + D SAP A +LP ++ Q S
Sbjct: 1199 SVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDS 1258
Query: 1383 TDLELQAGQLDVKLPE-GPVPEGAGLKGHLPKLQMPSFKVPKVDLK--GPEIDIKGPKLD 1439
+ E G L + P+ G P A + G P P+V L P + K +D
Sbjct: 1259 VEDEEPPGSLGLPPPQAGVQPAAAAVSG----TTQPLGTGPRVSLSPHSPLLSPKVASMD 1314
Query: 1440 LKD------PKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEED 1478
KD P +V P S P+ + AP + D LEED
Sbjct: 1315 AKDLALQILPPCQVPPPSGPQS-PAGPQGLSAPEQQEDEDSLEED 1358
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 52.0 bits (123), Expect = 2e-05
Identities = 243/1125 (21%), Positives = 369/1125 (32%), Gaps = 192/1125 (17%)
Query: 440 AQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGP--PEIRVRVHDLKTPKFAFS 497
A P PG GEGE + + LS TEG + + D + +A +
Sbjct: 340 ADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEA 399
Query: 498 TEK-----EPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGD 552
++ EP + L K ++ S GL+ ++ W P T D
Sbjct: 400 DDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQD-GTVSWAVEAAPQT-----SD 453
Query: 553 EGDGEEGLQRTRITEEQDKGREDTE-----GQIRMPKFKIPSLGWSPSKHTKTGREKATE 607
G +++ Q+ E TE GQ +L +P E AT
Sbjct: 454 RG--------AYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQV----EVATR 501
Query: 608 DTEQGREGEATATADRRE-----QRRTEEGLKDKEDSDSMT--------NTTKIQLIHDE 654
T Q E E +TA + + ++EG+ + +S+T T + L D
Sbjct: 502 VTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDS 561
Query: 655 -KRLKKEQILT----EKEVATKDSKFKMPK--FKMPLFGASAPGKSMEASVDVSAPKVEA 707
+ LK+E L K VA + K +P A P ++ + SAPK A
Sbjct: 562 PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA 621
Query: 708 DVSLLSMQGD--LKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPS 765
+++S Q + L SV TP L+ D +L P P A+ + +
Sbjct: 622 AATIVSQQAEEGLTLPQDSVMTPPLPLQ------DTELSSAPKPVAAATL--VSQQAEEG 673
Query: 766 LKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKE 825
L +P+ P L L+ + DLS A K
Sbjct: 674 LTLPQDSAMTPPLPLQ----------------------------------DTDLSSAPKP 699
Query: 826 VTAKD--SKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKAT---D 880
V A S+ +P P ++D+ SAPK A +L S Q + T D
Sbjct: 700 VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 759
Query: 881 LSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVH--------LPK--VEMPSFKMPKVD 930
++ PP L +Q D L P P A V LP+ P + D
Sbjct: 760 SAMTPP---LPLQ----DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812
Query: 931 LKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEV-DVQAQKAKLDGAWLEGDLSLADK 989
L V + + + +T P P + + D A A A++
Sbjct: 813 LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 872
Query: 990 DVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQ 1049
+T P + +S+ K + A VS + E L+LP Q T L +Q
Sbjct: 873 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVS-QQAEEGLTLP--QDSAMTAPLPLQ 929
Query: 1050 PASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLD 1109
T + + V P+ E G P M ++ + P + K L
Sbjct: 930 --DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALP 987
Query: 1110 LKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFK 1169
T P+ +L V+ D P A+ G A +D DS M
Sbjct: 988 --------TVPE-PAALDQVQQDDPQPAAE------AGTPWAAQEDA---DSTLGMEALS 1029
Query: 1170 MPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVD- 1228
+P A G E + +S P EA + + GD D P LEV Q
Sbjct: 1030 LPE---PASGAGEEIAEALSRPGREACLEARAHTGDGAKPD---SPQKETLEVENQQEGG 1083
Query: 1229 -VKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEV 1287
L + H P A G P P+V Q + P + +G + T
Sbjct: 1084 LKPLAQEHGPRSA-LGGAREVPDAPPAACPEVS----QARLLSPAREERGLSGKSTPEPT 1138
Query: 1288 AVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPK-----------FKMP 1336
S + E + + GA D D + P+ ++P
Sbjct: 1139 LPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1198
Query: 1337 S------------FGVSAPGKSIEASV--DLSAPKVEADMSLPSMQGDLKTTDLSIQPPS 1382
S P ++ + D SAP A +LP ++ Q S
Sbjct: 1199 SVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDS 1258
Query: 1383 TDLELQAGQLDVKLPE-GPVPEGAGLKGHLPKLQMPSFKVPKVDLK--GPEIDIKGPKLD 1439
+ E G L + P+ G P A + G P P+V L P + K +D
Sbjct: 1259 VEDEEPPGSLGLPPPQAGVQPAAAAVSG----TTQPLGTGPRVSLSPHSPLLSPKVASMD 1314
Query: 1440 LKD------PKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEED 1478
KD P +V P S P+ + AP + D LEED
Sbjct: 1315 AKDLALQILPPCQVPPPSGPQS-PAGPQGLSAPEQQEDEDSLEED 1358
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 49.7 bits (117), Expect = 9e-05
Identities = 120/541 (22%), Positives = 192/541 (35%), Gaps = 64/541 (11%)
Query: 3903 GPEIDIKGPKLDLKDPKVEVTA-PDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDM 3961
G E + +G + + K P E A P+ E P V+ + ++P A+
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSP-VKEEAKSP---------------AEAKS 532
Query: 3962 TAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPP 4021
K+ + K P S + ++ + +P+ E S ++K+ + + P
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS----PAEVKSPEKAKSPA 588
Query: 4022 SADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK 4081
+ + A + + PV E A K P ++K P+ K + K
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP-AEVKSPEKAKSPTKEEAK 647
Query: 4082 GP-------KAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFK 4134
P K E +P+ + S ++ + ++P V+ E K +++K
Sbjct: 648 SPEKAKSPEKEEAKSPE--KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK-S 704
Query: 4135 MPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQA 4194
K K P V KS E + + +AK S + + +SP +A
Sbjct: 705 PEKAKSP---VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE-----KA 756
Query: 4195 GQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGP------ 4248
+DVK PE P + K K +K P+ K D K P
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816
Query: 4249 KADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDS--KFKMPKFKMP 4306
K +V +PV E P EV V+ P K + + +K + K+ K + PK K+
Sbjct: 817 KEEVKSPVKEEEKP-QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 4307 SFGVSAPGKSIEASLDVSALKVEAD----VSLPSMQGDLKTTHLSIQPPSADLEVQAGQE 4362
A K E+ V A K EA+ V P + K P EV +
Sbjct: 876 EKKEPAVEKPKESK--VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933
Query: 4363 D---VKLPEGPVH--EGAGLKGHL--PKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKV 4415
D K P P E A K K + P K PK + K + D + K K PK
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK-PKTEAKAKEDDKTLSKEPSK-PKA 991
Query: 4416 E 4416
E
Sbjct: 992 E 992
Score = 48.5 bits (114), Expect = 2e-04
Identities = 122/600 (20%), Positives = 209/600 (34%), Gaps = 67/600 (11%)
Query: 406 EGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARL 465
EG +EGG + EG +ET + A P + E E A+
Sbjct: 482 EGKEEEGG------EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE---AKS 532
Query: 466 SLRDTTEGGTQIGPPEIRVRV--HDLKTPKFAFSTEKEPERE-RRLSTPQRGKRQDASSK 522
++ + ++ PE + K+P A S EKE + + +P++ K A +
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK-SPAKEE 591
Query: 523 AGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRM 582
A + + + E A E + AEA+ +E + + +K + T+ +
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV---KEEAKSPAEVKSPEKAKSPTKEEA-- 646
Query: 583 PKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSM 642
K P SP K EKA + + A + + + ++ E K ++
Sbjct: 647 ---KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Query: 643 TNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSA 702
+ + +E + ++ KE A K K P + A ++DV +
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763
Query: 703 PKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQ 762
P+ +TP+ + + + P PE A
Sbjct: 764 PE--------------------AKTPAKE--------EARSPADKFPEKAKSPVKEEVKS 795
Query: 763 RPSLKMP-KVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSL 821
K P K D K P+ ++ PK E VK EV V+ P K + +
Sbjct: 796 PEKAKSPLKEDAKAPEKEI--PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853
Query: 822 ADKEVTAKDS--KFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKAT 879
+K+ + K+ K + PK K+ A K E V+ A K EA+ D K
Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE--AKKEEAE--------DKKKV 903
Query: 880 DLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVK 939
+ A +EV+ + E E K P P+ K K + K
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP--SKPAEKKEAAPEKKDTKEEK 961
Query: 940 GPKLDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFK 999
K + K PK E A + + +L +A+KA+ + + D +K K +K K
Sbjct: 962 AKKPEEK-PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 48.1 bits (113), Expect = 2e-04
Identities = 109/554 (19%), Positives = 199/554 (35%), Gaps = 50/554 (9%)
Query: 3433 EVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSI 3492
E P E + +P + E S AE K+ + K P S
Sbjct: 500 ETKSPPAE-EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 3493 EASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGL 3552
++ + +P+ E S ++K+ + + P + + A E + PV E A
Sbjct: 559 KSPPEAKSPEKEEAKS----PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 3553 KGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGP-------KAEVRVPDVEVSLPSVE 3605
K+P ++K P+ K + K P K E + P+ S V+
Sbjct: 615 PAEAKSPVKEEAKSP-AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS--PVK 671
Query: 3606 VDVQAP-KAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVS 3664
+ ++P KAK ++ + +K + + K P+ + +P K S + +
Sbjct: 672 AEAKSPEKAK---SPVKAEAKSPEKAKSPVKEEAKSPE------KAKSPVKEEAKSPEKA 722
Query: 3665 APKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKV 3724
V+ + P + + + P A +A +DVK PE + P + K
Sbjct: 723 KSPVKEEAKTPE-KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 3725 EMPSLKMPKVDLKGPQ-------VDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPR 3777
+ K ++K P+ D K P+ ++ K EV +P E P EV V+ P
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP-KKEEVKSPVKEEEKPQ-EVKVKEPP 839
Query: 3778 AKLDSAQLEGDLSLADKDVTAKDS--KFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEA 3835
K + + +K + K+ K + PK K+ A K E+ V + E
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 3836 DVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFK 3895
+P+ + + P ++ A+ + + P++A K +
Sbjct: 900 KKKVPTPEKE--------APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 951
Query: 3896 MPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLS 3955
K D K E K P+ + PK E A + + +L +A A+ + + D
Sbjct: 952 PEKKDTK--EEKAKKPE---EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Query: 3956 LADKDMTAKDSKFK 3969
+K K +K K
Sbjct: 1007 PPEKATEDKAAKGK 1020
Score = 47.0 bits (110), Expect = 6e-04
Identities = 104/522 (19%), Positives = 175/522 (33%), Gaps = 63/522 (12%)
Query: 3701 QMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAP 3760
+ + K EG+ EG G +E E + P + P+ + K P + S AE +P
Sbjct: 475 EKEAKEEEGKEEEG-GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 3761 DVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGK 3820
+ E + EV +AK AK+ P+ K P +
Sbjct: 534 EKEEAKSPAEVK-SPEKAKSP----------------AKEEAKSPPEAKSPEKEEAKSPA 576
Query: 3821 SIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEA 3880
+++ +P E + K+ + P A V+ + V EEA
Sbjct: 577 EVKSPEKAKSPAKE----------EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 3881 GLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEA 3940
+ K P+ + + K P+ K E +P+ S V EA
Sbjct: 627 KSPAEV--------KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS----PVKAEA 674
Query: 3941 PGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEA 4000
+ + ++ + +K + + K P+ +P K S + V+
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE------KAKSPVKEEAKSPEKAKSPVKE 728
Query: 4001 DVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFK 4060
+ P + + + P A +A +DVK PE P + K +
Sbjct: 729 EAKTPE-KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 4061 MPKVDLKGPQ-------IDVKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGV 4113
K ++K P+ D K P+ ++ PK E VK EV V+ P K +
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEI--PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 4114 QLEGDLSLADKDVTAKDS--KFKMPKFKMPSFGVSAPGKSMEASVDV--SELKAKADVSL 4169
+ +K + K+ K + PK K+ A K E+ V+ E + K V
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905
Query: 4170 PSMQGDLKTTDLSIQSPSADLEVQAGQVD---VKLPEGPLPK 4208
P + K P EV + D K P P K
Sbjct: 906 PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Score = 46.6 bits (109), Expect = 7e-04
Identities = 124/577 (21%), Positives = 205/577 (35%), Gaps = 60/577 (10%)
Query: 1098 GPQVDVKGPKLDLKSPKAEVTA-PDVEVSLPSVEV---DVEAPGAKLDSARLEGELSLAD 1153
G + + +G + + KSP AE A P+ E P E EA + + A+ E+ +
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 1154 KDVT-AKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLS 1212
K + AK+ P+ K P + +++ +P E S + K+ + +
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS----PAEAKSPEKA 604
Query: 1213 IQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPK 1272
P + + A E P +K P+ + E + P+
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPA--------------EVKSPEKAKSPTKEEAKSPE 650
Query: 1273 LDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPK 1332
K E + E A S V +A + + + + +K + + K P+
Sbjct: 651 KAKSPEKEEAKSPEKAKS----PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 1333 FKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQL 1392
+P K S + + V+ + P + + + P +A L
Sbjct: 707 ------KAKSPVKEEAKSPEKAKSPVKEEAKTPE-KAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 1393 DVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDP------KVE 1446
DVK PE P + K + K ++K PE K D K P K E
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE 819
Query: 1447 VTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVS 1506
V +P E P EV V+ P K + EE K KDSK K + P
Sbjct: 820 VKSPVKEEEKPQ-EVKVKEPPKKAE----EEKAPATPKTEEKKDSK----KEEAPKKEAP 870
Query: 1507 APGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP- 1565
P + V PK E+ V + + K + P+ + E A +V+VK P
Sbjct: 871 KPKVEEKKEPAVEKPK-ESKVEAKKEEAEDKK-----KVPTPEKEAPA-KVEVKEDAKPK 923
Query: 1566 -VSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKVEVTAPDVKMSLS 1622
+E A + K + PS K + + D K K + PK E A + +LS
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 1623 SMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFK 1659
+A +A+ + + D +KA K +K K
Sbjct: 984 KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 45.1 bits (105), Expect = 0.002
Identities = 120/588 (20%), Positives = 212/588 (36%), Gaps = 51/588 (8%)
Query: 603 EKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQI 662
E+ TE+T+ E + +E+ EE ++E+++ TK + +KE
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 663 LTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTD 722
KE A ++ K P+ + + A KS E + + + ++ S + + +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEA--KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 723 LSVQTP----SADLEVQDGQVDVKLPE---GPLPEGASLKGHLPKVQRPSLKMPKVDLKG 775
V++P S E + K PE P+ E A + K P ++K
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP-AEVKS 634
Query: 776 PKLDLKGPKAEVTAPDVKMSLSSME----------VDVQAPRAKLDGARLEGDLSLADKE 825
P+ K E +P+ S E V +A + + ++ + +K
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 826 VTAKDSKFKMP-KFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQ 884
+ + K P K K P V KS E + +P E + + +K S
Sbjct: 695 KSPVKEEAKSPEKAKSP---VKEEAKSPEKA---KSPVKEEAKTPEKAKSPVKEEAKS-- 746
Query: 885 PPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLD 944
P A +A +DVK PE P + K + K ++K P+ K D
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 945 LKGP------KAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDS-- 996
K P K EV +P E P EV V+ K + +K + K+
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKP-QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 997 KFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLK 1056
K + PK K+ A K ++ V+ + E +P+ + + PA ++K
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE--------APAKVEVK 917
Query: 1057 VQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAE 1116
A + P+ A K + P+ K K + K K + K PK E
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAK----EPSKPAEKKEAAPEKKDTKEEKAKKPEEK-PKTE 972
Query: 1117 VTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFK 1164
A + + +L +A A+ S+ + + +K K ++ K
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 43.1 bits (100), Expect = 0.008
Identities = 105/484 (21%), Positives = 169/484 (34%), Gaps = 42/484 (8%)
Query: 2179 SPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPK 2238
SP K EA ++K+ + + P + K A + + PV EE
Sbjct: 566 SPEKEEA-----KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620
Query: 2239 LQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPS-----VEVDVKAPGA 2293
K P ++K PE K + K P+ + E P V+ + K+P
Sbjct: 621 PVKEEAKSP-AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679
Query: 2294 KLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVS 2353
+ E K +++K + V KS E + S +K EA
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSP----EKAKSPVKEEAKSPEKAK--SPVKEEAKTP 733
Query: 2354 LPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPK 2413
+ + + P A +A +DVK PE P + K + K
Sbjct: 734 EKAKS---PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 2414 VDLKGPQIDVKGPKLDLKGP------KTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEG 2467
++K P+ K D K P K +V +P E +P EV V+ P K +
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ-EVKVKEPPKKAEEEKAPA 849
Query: 2468 DLSVADKDVTTKDS--RFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGD 2525
+K + K+ + + PK K+ A K E+ V+ A K EA+ D
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE--AKKEEAE--------D 899
Query: 2526 LKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQ 2585
K + A +EV+ + E E K P P+ K K
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP--SKPAEKKEAAPEKKDT 957
Query: 2586 LDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKD 2645
+ K K + K PK E A + + +LS +A +A+ + + D +K K
Sbjct: 958 KEEKAKKPEEK-PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016
Query: 2646 SKFK 2649
+K K
Sbjct: 1017 AKGK 1020
Score = 42.0 bits (97), Expect = 0.018
Identities = 112/543 (20%), Positives = 192/543 (35%), Gaps = 43/543 (7%)
Query: 2583 GPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVT 2642
G + + +G + + K P AE A + + S ++ + ++P A+ E S A+
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSPEKEEAKSPAE---V 544
Query: 2643 AKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPS 2702
K K P + A E +E+K P+ + + K+ + P
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE-EAKSPAEAKSPEK 603
Query: 2703 AQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKG 2762
A+ V+ + V E A + K PE + + K P
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEV--------KSPEKAKSPTKEEAKSPEKAKSP 655
Query: 2763 PKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPS 2822
K E +P+ + S ++ + ++P + E +K + + K P+
Sbjct: 656 EKEEAKSPE--KAKSPVKAEAKSPEKAKSPVKAEA--KSPEKAKSPVKEEAKSPE----- 706
Query: 2823 FGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLP 2882
+P K S + ++ V+ + P + + P A+ +A +DVK P
Sbjct: 707 -KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK-SPEKAKSPEKAKTLDVKSP 764
Query: 2883 EGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGP------KAEVTAPD 2936
E P + K + K ++K P+ K D K P K EV +P
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 2937 VEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDS--KFKMPKFKMPSFGVSAPG 2994
E P EV V+ P K + + +K + K+ K + PK K+ A
Sbjct: 825 KEEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 2995 KSIEVSVDVSAPKVEAE----VSLPSMQGDLKTTDISIEPPSAQLEVQAGQV-DLKLPEG 3049
K E V+ A K EAE V P + K P + EV + D K E
Sbjct: 884 KPKESKVE--AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 3050 HVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGM 3109
P A K P+ + + K + P+ + K K D K + + P E ++
Sbjct: 942 SKP--AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA-KEDDKTLSKEPSKPKAEKAEKSS 998
Query: 3110 EVD 3112
D
Sbjct: 999 STD 1001
Score = 41.2 bits (95), Expect = 0.030
Identities = 115/576 (19%), Positives = 205/576 (35%), Gaps = 58/576 (10%)
Query: 1593 GPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRA----KLDGAQLEGDLSLAD 1648
G + + +G + + K P E A K + S ++ + ++P + + A+ ++ +
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 1649 KAVT-AKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLS 1707
KA + AK+ P+ K P + E K A+V P +
Sbjct: 549 KAKSPAKEEAKSPPEAKSP---------------EKEEAKSPAEVKSPEKAKSPAKEEA- 592
Query: 1708 IQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK 1767
+SP+ + + VK E P A +K P+ A + + K P+
Sbjct: 593 -KSPAEAKSPEKAKSPVK-EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Query: 1768 LDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPK 1827
K E +P+ S V+ + ++P V+ E K +++K K
Sbjct: 651 KAKSPEKEEAKSPEKAKS--PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK-SPEK 707
Query: 1828 FKMPSFGVSAPGKSIE-ASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQ 1886
K P V KS E A V E + ++ + K+ + A +A
Sbjct: 708 AKSP---VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE------KAKSPEKAKT 758
Query: 1887 VDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGP------KA 1940
+D+K PE + P + K + K ++K P+ K D K P K
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 1941 EVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDS--KFKMPKFKMPSF 1998
EV +P E P EV V+ K + + +K + K+ K + PK K+
Sbjct: 819 EVKSPVKEEEKP-QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 1999 GVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPE 2058
A + E+ V+ + E +P+ + + P ++K +
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE--------APAKVEVKEDAKPKEKTEVA 929
Query: 2059 GHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEVSLPS 2118
P+ A K E K D K + K P+ + PK E + + + +L
Sbjct: 930 KKEPDDAKAKEPSKPAEKKEAAPEKKDTK--EEKAKKPE---EKPKTEAKAKEDDKTLSK 984
Query: 2119 MEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFK 2154
+A +A+ S+ Q D K K +K K
Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 37.4 bits (85), Expect = 0.44
Identities = 120/590 (20%), Positives = 201/590 (34%), Gaps = 76/590 (12%)
Query: 3073 KVDRKGPQIDVKGPKLDLKGPKTDVTA-PDVEVSQPGMEV---DVEAPGAKLDGARLEGD 3128
K + G + + +G + + K P + A P+ E P E EA + + A+ +
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 3129 LSLADKDVT-AKDSKFKMPKFKMPS-------FGVSAPGKSIEVLVDVSAPKVEADLSLP 3180
+ +K + AK+ P+ K P V +P K+ + + EA
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603
Query: 3181 SMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVD 3240
+ + E S E +VK PE K + P+ K +
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE--------------KAKSPT----KEE 645
Query: 3241 RKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSME---VDVEAPGAKLDGARLEGDLSLA 3297
K P+ K + K P+ + E P V EA + + ++ +
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 3298 DKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLS 3357
+K + + K P+ +A +P K + + + + + P +
Sbjct: 706 EKAKSPVKEEAKSPE------KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE----- 754
Query: 3358 IQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPK 3417
+A +DVK PE P + K + K ++KSP+ K
Sbjct: 755 ----------KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 3418 LDLKVP------KAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDS 3471
D K P K EV P E P EV V+ P K + + EK + K+
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 3472 --KFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSAD 3529
K + PK K+ A + E+ V A K EA+ D K + A
Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESK--VEAKKEEAE--------DKKKVPTPEKEAPAK 913
Query: 3530 LEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPK 3589
+EV+ E E E K P P+ K K + K K + K PK
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAKAKEP--SKPAEKKEAAPEKKDTKEEKAKKPEEK-PK 970
Query: 3590 AEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFK 3639
E + + + +L +A KA+ + + D +K K +K K
Sbjct: 971 TEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 36.6 bits (83), Expect = 0.75
Identities = 114/584 (19%), Positives = 212/584 (36%), Gaps = 74/584 (12%)
Query: 2913 GPQIDVKGPKLDLKGPKAEVTA-PDVEVSLPSVEV---DVEAPRAKLDGARLEGDLSLAD 2968
G + + +G + + K P AE A P+ E P E EA + + A+ ++ +
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 2969 KDVT-AKDSKFKMPKFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDIS 3027
K + AK+ P+ K P + ++ +P E E P+ + K+ + +
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE-EAKSPA---EAKSPEKA 604
Query: 3028 IEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK 3087
P + + A + K P V E A + K P+ + + + K P+
Sbjct: 605 KSPVKEEAKSPA---EAKSP---VKEEAKSPAEV--------KSPEKAKSPTKEEAKSPE 650
Query: 3088 LDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMP- 3146
K + +P+ S V EA + + ++ + +K + + K P
Sbjct: 651 KAKSPEKEEAKSPEKAKSP----VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 3147 KFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQ 3206
K K P V KS E +P E + + +K S P A+ +A
Sbjct: 707 KAKSP---VKEEAKSPE---KAKSPVKEEAKTPEKAKSPVKEEAKS--PEKAKSPEKAKT 758
Query: 3207 VDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPD 3266
+DVK PE + + P+ K P+ + + ++K P+ K D AP+
Sbjct: 759 LDVKSPEAKTPAKE-------EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811
Query: 3267 VEV------------SQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDS--KFKMPK 3312
E+ + EV V+ P K + + +K + K+ K + PK
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 3313 FKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQV 3372
K+ + A K ++ V+ +AE +P+ + K +++ + +V
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE---KEAPAKVEVKEDAKPKEKTEV 928
Query: 3373 DVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL--KVPKAEVTVP 3430
K P+ K + PS K + + D K K + PK E
Sbjct: 929 AKKEPDD------------AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK 976
Query: 3431 DVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFK 3474
+ + +L +A +A+ + + D EK K +K K
Sbjct: 977 EDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 34.7 bits (78), Expect = 2.8
Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 32/131 (24%)
Query: 5619 SQEATTPLADEGRAPKDK-PESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQT 5677
S EA TP +E R+P DK PE K S V E + K+ + +P++
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAK--------------SPVKE---EVKSPEKAKSPLKE 805
Query: 5678 QPEARPEAELPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAELE-EQKLQEETITFFDA 5736
+A PE E+PKK+E SP K+ + ++ E +K +EE
Sbjct: 806 DAKA-PEKEIPKKEE------------VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852
Query: 5737 RESFSPEEKEE 5747
E +KEE
Sbjct: 853 TEEKKDSKKEE 863
Score = 34.3 bits (77), Expect = 3.7
Identities = 30/157 (19%), Positives = 63/157 (40%), Gaps = 18/157 (11%)
Query: 5600 ADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVD 5659
A+ +E + E +EA +P+ +E ++P + +K
Sbjct: 494 AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA--------------- 538
Query: 5660 ETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFPKLGFSSSPTK---KSKSTE 5716
++ + K+ + +P + + ++ PEA+ P+K+E + SP K KS +
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 5717 DGAELEEQKLQEETITFFDARESFSPEEKEEGELIGP 5753
E + ++EE + +A+ E K E+ P
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.9 bits (115), Expect = 1e-04
Identities = 48/201 (23%), Positives = 86/201 (42%), Gaps = 17/201 (8%)
Query: 481 EIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPG 540
EIR R +++T K +KE E ER+ +R KR+ K +G++ +
Sbjct: 37 EIREREREIETRK---EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
Query: 541 REPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKT 600
+ + +GEE +R + E++++GR EG+ R K + + +
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKK-KEKKERGRTSKEGKERERKEE-------RKREERK 145
Query: 601 GREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKE 660
RE+ E+ E+ RE + +R++ EE K+KE + + K KKE
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE------RNRKERKKE 199
Query: 661 QILTEKEVATKDSKFKMPKFK 681
+ E+ K+ K K + K
Sbjct: 200 RERKERRERKKERKKKEERKK 220
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 48.9 bits (115), Expect = 1e-04
Identities = 61/231 (26%), Positives = 99/231 (42%), Gaps = 21/231 (9%)
Query: 500 KEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGR-EPTTHAEAQGDEGDGEE 558
KEP+R + R R +A K+G K E++ G GR + G +G GEE
Sbjct: 123 KEPKRGGLKKSFSRD-RDEAGGKSGEKPKEEKII-RGIDKGRVRAAVDKKEAGKDGRGEE 180
Query: 559 GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEAT 618
T+ EE+ KG + G R K + +E A ++ ++ +GE
Sbjct: 181 RAVATK-KEEEKKGSDRNTGLSR-----------DKDKKREEMKEVAKKEDDEKVKGERR 228
Query: 619 ATADRREQRRTEE--GLKD--KEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSK 674
T R+E + + G D KED T D++++KK + L EKE A DSK
Sbjct: 229 NTDTRKEGEKMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKE-AKDDSK 287
Query: 675 FKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSV 725
K P+ + P G + P + + +AP + + D + T+++V
Sbjct: 288 TKTPEKQTP-SGPTKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEMTEVNV 337
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sapiens]
Length = 486
Score = 48.5 bits (114), Expect = 2e-04
Identities = 87/383 (22%), Positives = 162/383 (42%), Gaps = 54/383 (14%)
Query: 2016 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQTGQVD--------VKLPEGHV 2061
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E ++
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 2062 PEGAGLK-----GHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKDPKVEMRVPDVEVS 2115
P+ + G++PK + + + D+ K P+ I+ K DL E P E
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 141
Query: 2116 LPSMEVDVQAPR----AKLD---SAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAP 2168
+P P+ AK S + D+ + ++ T + + +PK
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 199
Query: 2169 GKSIEASVDVSPPKVEADMS------LPSMQGDL-KTTDLSIQPLSADVKVQAGQVDVKL 2221
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ + ++
Sbjct: 200 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQP 257
Query: 2222 LEGPVPEEV-----GLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 2274
EG +P+ + +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 258 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 317
Query: 2275 PD------VEVSLPSVEVDV-KAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLS 2327
+ +E ++P E+D+ K+P + + SL ++ +K+ P+ + +
Sbjct: 318 KEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETME 376
Query: 2328 FGVSALGKSIEASADVSALKVEA 2350
F K I + D A EA
Sbjct: 377 FPEGDKVKVILSKEDFEASLKEA 399
Score = 47.0 bits (110), Expect = 6e-04
Identities = 78/320 (24%), Positives = 136/320 (42%), Gaps = 52/320 (16%)
Query: 3666 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQAGQMD--------VKLPEGQV 3711
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 3712 PEGAGLK-----EHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKVSKAEVTAPDVEVS 3765
P+ + ++PK + + + D+ K P+ I+ K DL S E P E
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 141
Query: 3766 LPSVEVDVQAPR----AKLD---SAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAP 3818
+P P+ AK S E D+ + ++ T + + +PK
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 199
Query: 3819 GKSIEASVHVSAPKVEADVS------LPSMQGDL-KTTDLSIQPHSADLTVQARQVDMKL 3871
G +ASV S PK E D+S + +GDL K+ + +IQP D+ + ++
Sbjct: 200 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEA-IQP 257
Query: 3872 LEGHVP---EEA--GLKGHLPKVQMPSFKMPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 3924
EG +P EEA +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 258 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 317
Query: 3925 PD------VEVSLPSVEVDV 3938
+ +E ++P E+D+
Sbjct: 318 KEGDIPKSLEEAIPPKEIDI 337
Score = 44.7 bits (104), Expect = 0.003
Identities = 91/420 (21%), Positives = 166/420 (39%), Gaps = 64/420 (15%)
Query: 3570 DLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSV-EVDVQAPKAKLDAGRLEGDLSLAD 3628
DL + PK D +E + E +P E +Q+ K L E + +
Sbjct: 21 DLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSS-EKAIQPKE 79
Query: 3629 KDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDL-KTTDLS 3687
++ +K PK G +ASV S PK +GD+ K + +
Sbjct: 80 SNIPKSSAKPIQPKL----------GNIPKASVKPSQPK----------EGDIPKAPEET 119
Query: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAG--LKEHLPKVEMPSLK--MPKVD--LKGPQV 3741
IQ DL ++ + ++ EG +P+ + ++ L + S+K PK K P+
Sbjct: 120 IQSKKEDLP-KSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE 178
Query: 3742 DIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDS 3801
I+ + D+ S A+ P + ++P V P+ S E + + D+
Sbjct: 179 TIQPKEGDIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLE 237
Query: 3802 KFKMPKF----KMPSFGVSAPGKSIEASVHVSAPKVEADV------SLPSMQGDL-KTTD 3850
+ PK K P + I S+ + E D+ ++ +GD+ K+ +
Sbjct: 238 EAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPE 297
Query: 3851 LSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKG 3910
+IQP D+ +Q ++ EG +P+ L+ +P PK EIDI
Sbjct: 298 EAIQPKEGDIPKSPKQA-IQPKEGDIPKS--LEEAIP---------PK------EIDIPK 339
Query: 3911 PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKL----DGARLEGDLSLADKDMTAKDS 3966
+ PK + + +E + PS E D+ P + +G +++ LS D + + K++
Sbjct: 340 SPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEA 399
Score = 43.5 bits (101), Expect = 0.006
Identities = 85/382 (22%), Positives = 160/382 (41%), Gaps = 52/382 (13%)
Query: 1026 PKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGA-----GLKGH 1080
PK A+ S P K+++ +IQP D+ +A + ++ + LP+ + + +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIP-KAPEETIQSKKEDLPKSSEKAIQPKESN 81
Query: 1081 LPK-----VEMPSFKMPKVALKGPQV---DV-KGPKLDLKSPKAEVTAPDVEVSLPSVEV 1131
+PK ++ +PK ++K Q D+ K P+ ++S K ++ E P E
Sbjct: 82 IPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EG 140
Query: 1132 DVEAPGAKLDSARLEGELSLADKDVTAKDSRF-KMPKFKMPSFGASAP-----------G 1179
D+ AK +L + K K+S K P+ + P G
Sbjct: 141 DIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLG 200
Query: 1180 KSIEASVDVSAPKVEADVS------LPSMQGDL-KTTDLSIQPPSADLEVHAGQVDVKLL 1232
+ASV S PK E D+S + +GDL K+ + +IQP D+ + + ++
Sbjct: 201 NIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPK 258
Query: 1233 EGHVPEG-----AGFKGHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDL-KGHKAEVTAH 1285
EG +P+ +G +PK +++ K D+ K P+ ++ + D+ K K +
Sbjct: 259 EGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPK 318
Query: 1286 E------VAVSLPSVEVDM-QAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSF 1338
E + ++P E+D+ ++P + + D SL ++ +K+ P+ + F
Sbjct: 319 EGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEF 377
Query: 1339 GVSAPGKSIEASVDLSAPKVEA 1360
K I + D A EA
Sbjct: 378 PEGDKVKVILSKEDFEASLKEA 399
Score = 41.6 bits (96), Expect = 0.023
Identities = 82/391 (20%), Positives = 149/391 (38%), Gaps = 70/391 (17%)
Query: 1521 PKVEADVSLPSMQGDLKATDLSIQPPSADL------EVQAGQVDV-------------KL 1561
PK A+ S P K+++ +IQP D+ +Q+ + D+ +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 1562 PEGPVSEGAGLKGHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKVEVTAPDVKMS 1620
P+ G++PK + + + D+ K P+ ++ K DL E P
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQP----- 137
Query: 1621 LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKF-KMPKFKMPSFGVSAP------ 1673
E D+ AK +L + K K+S K P+ + P
Sbjct: 138 ---KEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 194
Query: 1674 -----GKSIEASVDVSEPKVEADVS------LPSMQGDL-KTTDLSIQ--------SPSA 1713
G +ASV S+PK E D+S + +GDL K+ + +IQ SP
Sbjct: 195 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEE 253
Query: 1714 DLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSL--------KMPKVALKGPQMDV-K 1764
++ + G + L E P+ +G +PK ++ K P+ A++ + D+ K
Sbjct: 254 AIQPKEGDIPKSLEEAIQPK----EGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK 309
Query: 1765 GPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFK 1824
PK ++ PK + +E ++P E+D+ + + + ++ +K+
Sbjct: 310 SPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDIL 368
Query: 1825 MPKFKMPSFGVSAPGKSIEASVDVSAPKVEA 1855
P+ + F K I + D A EA
Sbjct: 369 KPEEETMEFPEGDKVKVILSKEDFEASLKEA 399
Score = 41.6 bits (96), Expect = 0.023
Identities = 68/323 (21%), Positives = 134/323 (41%), Gaps = 58/323 (17%)
Query: 3996 PKVEADVSLPSMQGDLKATDLSVQPPSADL------EVQAGQVD--------VKLPEGPV 4041
PK A+ S P K+++ ++QP D+ +Q+ + D ++ E +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 4042 PEGASLK-----GHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKAEVTAP---DV 4092
P+ ++ G++PK + + + D+ K P+ ++ K DL E P D+
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDI 142
Query: 4093 KMSLS-----------------SMEVDVQAPRAKLDGVQ-LEGDLSLADKDVTAKDSKFK 4134
S + S + P++ + +Q EGD+ + +AK + K
Sbjct: 143 PKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS----SAKPIQPK 198
Query: 4135 MPKFKMPSFGVSAP-----GKSMEASVDVSE--LKAKADVSLPSMQGDL-KTTDLSIQSP 4186
+ S S P KS E ++ E L + ++ +GD+ K+ + +IQ
Sbjct: 199 LGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK 258
Query: 4187 SADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDV-KGPKLDL 4245
D+ + ++ EG +PK K +P K P+ A++ + D+ K PK +
Sbjct: 259 EGDIPKSLEEA-IQPKEGDIPKSPEETIQPKKGDIP--KSPEEAIQPKEGDIPKSPKQAI 315
Query: 4246 KGPKADVMTPVVEVSLPSMEVDV 4268
+ PK + +E ++P E+D+
Sbjct: 316 Q-PKEGDIPKSLEEAIPPKEIDI 337
Score = 40.4 bits (93), Expect = 0.052
Identities = 84/401 (20%), Positives = 158/401 (39%), Gaps = 64/401 (15%)
Query: 1191 PKVEADVSLPSMQGDLKTTDLSIQPPSADLE--------------VHAGQVDVKLLEGHV 1236
PK A+ S P K+++ +IQP D+ + + ++ E ++
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 1237 PEGAGFK-----GHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDLKGHKAEVTAHEVAVS 1290
P+ + G++PK + + + D+ K P+ ++ K DL E +
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE--------A 134
Query: 1291 LPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKF-KMPKFKMPSFGVSAP------ 1343
+ E D+ AK +L + K K+S K P+ + P
Sbjct: 135 IQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 194
Query: 1344 -----GKSIEASVDLSAPKVEADMS------LPSMQGDL-KTTDLSIQPPSTDLELQAGQ 1391
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ +
Sbjct: 195 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPE 252
Query: 1392 LDVKLPEGPVPEG-----AGLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPK 1444
++ EG +P+ +G +PK + + K D+ K PE I+ + D+ K PK
Sbjct: 253 EAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPK 312
Query: 1445 VEVTAPD------VEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKF 1498
+ + +E ++P E+D+ + + ++ ++ +K+ P+
Sbjct: 313 QAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEE 372
Query: 1499 KMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKAT 1539
+ F K I + D A EA L ++ D AT
Sbjct: 373 ETMEFPEGDKVKVILSKEDFEASLKEAGERLVAV--DFSAT 411
Score = 37.0 bits (84), Expect = 0.57
Identities = 78/375 (20%), Positives = 147/375 (39%), Gaps = 53/375 (14%)
Query: 550 QGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDT 609
Q EGD + + T ++++D + +E I+ + IP P + KA+
Sbjct: 46 QPKEGDIPKAPEETIQSKKEDLPKS-SEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKP 104
Query: 610 EQGREGEATATADRREQ-------RRTEEGLKDKEDSDSMTNTTKIQ--LIHDEKRLKKE 660
Q +EG+ + Q + +EE ++ KE ++ IQ L + K K
Sbjct: 105 SQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKP 164
Query: 661 QILTEKEVATKDSKFKMPKFKMPLFGASAP-----GKSMEASVDVSAPKVEADVS----- 710
E ++ + PK ++ P G +ASV S PK E D+S
Sbjct: 165 SQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDISKSPEE 223
Query: 711 -LLSMQGDL-KTTDLSVQ--------TPSADLEVQDGQVDVKLPEGPLPEGASL------ 754
+ +GDL K+ + ++Q +P ++ ++G + L E P+ +
Sbjct: 224 AIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEE 283
Query: 755 -----KGHLPKVQRPSLKMPKVDL-KGPKLDLKGPKAEVTAPDVKMSLSSMEVDV-QAPR 807
KG +PK +++ + D+ K PK ++ PK ++ ++ E+D+ ++P
Sbjct: 284 TIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPE 342
Query: 808 AKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADV 867
+ + SL ++ +K+ P+ + F D V V K + +
Sbjct: 343 ETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEFPEG-------DKVKVILSKEDFEA 394
Query: 868 SLSSMQGDLKATDLS 882
SL L A D S
Sbjct: 395 SLKEAGERLVAVDFS 409
Score = 35.8 bits (81), Expect = 1.3
Identities = 101/447 (22%), Positives = 169/447 (37%), Gaps = 68/447 (15%)
Query: 863 VEADVSLSSMQGD-LKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEM 921
+ + S +S +GD L + + P D ++ + ++ EG +P+ + K ++
Sbjct: 8 MRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDL 67
Query: 922 PSFKMPKVDLKGPQIDVKG-----PKLDLKGPKAEV-TAPDGEVSLP-SMEVDVQAQKAK 974
P + K I PKL PKA V + E +P + E +Q++K
Sbjct: 68 PKSSEKAIQPKESNIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDIPKAPEETIQSKKED 126
Query: 975 LDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSL 1034
L + E + + D+ +K PK G K V S PK E+D+
Sbjct: 127 LPKS-SEEAIQPKEGDIPKSSAKPIQPKL----------GNIAKTSVKPSQPK-ESDIP- 173
Query: 1035 PSMQGDLKTTDLSIQPASTDL-KVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPK 1093
K+ + +IQP D+ K A + KL G++P+ A +K PK E K P+
Sbjct: 174 -------KSPEETIQPKEGDIPKSSAKPIQPKL--GNIPK-ASVKPSQPK-EGDISKSPE 222
Query: 1094 VALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDV-----EAPGAKLDSARLEGE 1148
A++ + D+ + PK E ++ E D+ EA K E
Sbjct: 223 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPE 282
Query: 1149 LSLADK--DVTAKDSRFKMPKF----KMPSFGASAPGKSIEASVDVSAPKVEADVSLPSM 1202
++ K D+ PK K P I S++ + P E D+
Sbjct: 283 ETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIP---- 338
Query: 1203 QGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK 1262
K+ + +IQP D K LE P +G + K + +++ P +
Sbjct: 339 ----KSPEETIQPKEDD--------SPKSLEEATPSK---EGDILKPEEETMEFP----E 379
Query: 1263 GPQVEVRGPKLDLKGHKAEVTAHEVAV 1289
G +V+V K D + E VAV
Sbjct: 380 GDKVKVILSKEDFEASLKEAGERLVAV 406
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sapiens]
Length = 553
Score = 48.5 bits (114), Expect = 2e-04
Identities = 87/383 (22%), Positives = 162/383 (42%), Gaps = 54/383 (14%)
Query: 2016 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQTGQVD--------VKLPEGHV 2061
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E ++
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 149
Query: 2062 PEGAGLK-----GHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKDPKVEMRVPDVEVS 2115
P+ + G++PK + + + D+ K P+ I+ K DL E P E
Sbjct: 150 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 208
Query: 2116 LPSMEVDVQAPR----AKLD---SAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAP 2168
+P P+ AK S + D+ + ++ T + + +PK
Sbjct: 209 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 266
Query: 2169 GKSIEASVDVSPPKVEADMS------LPSMQGDL-KTTDLSIQPLSADVKVQAGQVDVKL 2221
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ + ++
Sbjct: 267 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQP 324
Query: 2222 LEGPVPEEV-----GLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 2274
EG +P+ + +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 325 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 384
Query: 2275 PD------VEVSLPSVEVDV-KAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLS 2327
+ +E ++P E+D+ K+P + + SL ++ +K+ P+ + +
Sbjct: 385 KEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETME 443
Query: 2328 FGVSALGKSIEASADVSALKVEA 2350
F K I + D A EA
Sbjct: 444 FPEGDKVKVILSKEDFEASLKEA 466
Score = 47.0 bits (110), Expect = 6e-04
Identities = 78/320 (24%), Positives = 136/320 (42%), Gaps = 52/320 (16%)
Query: 3666 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQAGQMD--------VKLPEGQV 3711
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E +
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 149
Query: 3712 PEGAGLK-----EHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKVSKAEVTAPDVEVS 3765
P+ + ++PK + + + D+ K P+ I+ K DL S E P E
Sbjct: 150 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 208
Query: 3766 LPSVEVDVQAPR----AKLD---SAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAP 3818
+P P+ AK S E D+ + ++ T + + +PK
Sbjct: 209 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 266
Query: 3819 GKSIEASVHVSAPKVEADVS------LPSMQGDL-KTTDLSIQPHSADLTVQARQVDMKL 3871
G +ASV S PK E D+S + +GDL K+ + +IQP D+ + ++
Sbjct: 267 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEA-IQP 324
Query: 3872 LEGHVP---EEA--GLKGHLPKVQMPSFKMPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 3924
EG +P EEA +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 325 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 384
Query: 3925 PD------VEVSLPSVEVDV 3938
+ +E ++P E+D+
Sbjct: 385 KEGDIPKSLEEAIPPKEIDI 404
Score = 44.7 bits (104), Expect = 0.003
Identities = 91/420 (21%), Positives = 166/420 (39%), Gaps = 64/420 (15%)
Query: 3570 DLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSV-EVDVQAPKAKLDAGRLEGDLSLAD 3628
DL + PK D +E + E +P E +Q+ K L E + +
Sbjct: 88 DLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSS-EKAIQPKE 146
Query: 3629 KDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDL-KTTDLS 3687
++ +K PK G +ASV S PK +GD+ K + +
Sbjct: 147 SNIPKSSAKPIQPKL----------GNIPKASVKPSQPK----------EGDIPKAPEET 186
Query: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAG--LKEHLPKVEMPSLK--MPKVD--LKGPQV 3741
IQ DL ++ + ++ EG +P+ + ++ L + S+K PK K P+
Sbjct: 187 IQSKKEDLP-KSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE 245
Query: 3742 DIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDS 3801
I+ + D+ S A+ P + ++P V P+ S E + + D+
Sbjct: 246 TIQPKEGDIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLE 304
Query: 3802 KFKMPKF----KMPSFGVSAPGKSIEASVHVSAPKVEADV------SLPSMQGDL-KTTD 3850
+ PK K P + I S+ + E D+ ++ +GD+ K+ +
Sbjct: 305 EAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPE 364
Query: 3851 LSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKG 3910
+IQP D+ +Q ++ EG +P+ L+ +P PK EIDI
Sbjct: 365 EAIQPKEGDIPKSPKQA-IQPKEGDIPKS--LEEAIP---------PK------EIDIPK 406
Query: 3911 PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKL----DGARLEGDLSLADKDMTAKDS 3966
+ PK + + +E + PS E D+ P + +G +++ LS D + + K++
Sbjct: 407 SPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEA 466
Score = 43.5 bits (101), Expect = 0.006
Identities = 85/382 (22%), Positives = 160/382 (41%), Gaps = 52/382 (13%)
Query: 1026 PKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGA-----GLKGH 1080
PK A+ S P K+++ +IQP D+ +A + ++ + LP+ + + +
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIP-KAPEETIQSKKEDLPKSSEKAIQPKESN 148
Query: 1081 LPK-----VEMPSFKMPKVALKGPQV---DV-KGPKLDLKSPKAEVTAPDVEVSLPSVEV 1131
+PK ++ +PK ++K Q D+ K P+ ++S K ++ E P E
Sbjct: 149 IPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EG 207
Query: 1132 DVEAPGAKLDSARLEGELSLADKDVTAKDSRF-KMPKFKMPSFGASAP-----------G 1179
D+ AK +L + K K+S K P+ + P G
Sbjct: 208 DIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLG 267
Query: 1180 KSIEASVDVSAPKVEADVS------LPSMQGDL-KTTDLSIQPPSADLEVHAGQVDVKLL 1232
+ASV S PK E D+S + +GDL K+ + +IQP D+ + + ++
Sbjct: 268 NIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPK 325
Query: 1233 EGHVPEG-----AGFKGHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDL-KGHKAEVTAH 1285
EG +P+ +G +PK +++ K D+ K P+ ++ + D+ K K +
Sbjct: 326 EGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPK 385
Query: 1286 E------VAVSLPSVEVDM-QAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSF 1338
E + ++P E+D+ ++P + + D SL ++ +K+ P+ + F
Sbjct: 386 EGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEF 444
Query: 1339 GVSAPGKSIEASVDLSAPKVEA 1360
K I + D A EA
Sbjct: 445 PEGDKVKVILSKEDFEASLKEA 466
Score = 41.6 bits (96), Expect = 0.023
Identities = 82/391 (20%), Positives = 149/391 (38%), Gaps = 70/391 (17%)
Query: 1521 PKVEADVSLPSMQGDLKATDLSIQPPSADL------EVQAGQVDV-------------KL 1561
PK A+ S P K+++ +IQP D+ +Q+ + D+ +
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 149
Query: 1562 PEGPVSEGAGLKGHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKVEVTAPDVKMS 1620
P+ G++PK + + + D+ K P+ ++ K DL E P
Sbjct: 150 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQP----- 204
Query: 1621 LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKF-KMPKFKMPSFGVSAP------ 1673
E D+ AK +L + K K+S K P+ + P
Sbjct: 205 ---KEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 261
Query: 1674 -----GKSIEASVDVSEPKVEADVS------LPSMQGDL-KTTDLSIQ--------SPSA 1713
G +ASV S+PK E D+S + +GDL K+ + +IQ SP
Sbjct: 262 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEE 320
Query: 1714 DLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSL--------KMPKVALKGPQMDV-K 1764
++ + G + L E P+ +G +PK ++ K P+ A++ + D+ K
Sbjct: 321 AIQPKEGDIPKSLEEAIQPK----EGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK 376
Query: 1765 GPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFK 1824
PK ++ PK + +E ++P E+D+ + + + ++ +K+
Sbjct: 377 SPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDIL 435
Query: 1825 MPKFKMPSFGVSAPGKSIEASVDVSAPKVEA 1855
P+ + F K I + D A EA
Sbjct: 436 KPEEETMEFPEGDKVKVILSKEDFEASLKEA 466
Score = 41.6 bits (96), Expect = 0.023
Identities = 68/323 (21%), Positives = 134/323 (41%), Gaps = 58/323 (17%)
Query: 3996 PKVEADVSLPSMQGDLKATDLSVQPPSADL------EVQAGQVD--------VKLPEGPV 4041
PK A+ S P K+++ ++QP D+ +Q+ + D ++ E +
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 149
Query: 4042 PEGASLK-----GHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKAEVTAP---DV 4092
P+ ++ G++PK + + + D+ K P+ ++ K DL E P D+
Sbjct: 150 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDI 209
Query: 4093 KMSLS-----------------SMEVDVQAPRAKLDGVQ-LEGDLSLADKDVTAKDSKFK 4134
S + S + P++ + +Q EGD+ + +AK + K
Sbjct: 210 PKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS----SAKPIQPK 265
Query: 4135 MPKFKMPSFGVSAP-----GKSMEASVDVSE--LKAKADVSLPSMQGDL-KTTDLSIQSP 4186
+ S S P KS E ++ E L + ++ +GD+ K+ + +IQ
Sbjct: 266 LGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK 325
Query: 4187 SADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDV-KGPKLDL 4245
D+ + ++ EG +PK K +P K P+ A++ + D+ K PK +
Sbjct: 326 EGDIPKSLEEA-IQPKEGDIPKSPEETIQPKKGDIP--KSPEEAIQPKEGDIPKSPKQAI 382
Query: 4246 KGPKADVMTPVVEVSLPSMEVDV 4268
+ PK + +E ++P E+D+
Sbjct: 383 Q-PKEGDIPKSLEEAIPPKEIDI 404
Score = 40.4 bits (93), Expect = 0.052
Identities = 84/401 (20%), Positives = 158/401 (39%), Gaps = 64/401 (15%)
Query: 1191 PKVEADVSLPSMQGDLKTTDLSIQPPSADLE--------------VHAGQVDVKLLEGHV 1236
PK A+ S P K+++ +IQP D+ + + ++ E ++
Sbjct: 90 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 149
Query: 1237 PEGAGFK-----GHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDLKGHKAEVTAHEVAVS 1290
P+ + G++PK + + + D+ K P+ ++ K DL E +
Sbjct: 150 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE--------A 201
Query: 1291 LPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKF-KMPKFKMPSFGVSAP------ 1343
+ E D+ AK +L + K K+S K P+ + P
Sbjct: 202 IQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 261
Query: 1344 -----GKSIEASVDLSAPKVEADMS------LPSMQGDL-KTTDLSIQPPSTDLELQAGQ 1391
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ +
Sbjct: 262 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPE 319
Query: 1392 LDVKLPEGPVPEG-----AGLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPK 1444
++ EG +P+ +G +PK + + K D+ K PE I+ + D+ K PK
Sbjct: 320 EAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPK 379
Query: 1445 VEVTAPD------VEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKF 1498
+ + +E ++P E+D+ + + ++ ++ +K+ P+
Sbjct: 380 QAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEE 439
Query: 1499 KMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKAT 1539
+ F K I + D A EA L ++ D AT
Sbjct: 440 ETMEFPEGDKVKVILSKEDFEASLKEAGERLVAV--DFSAT 478
Score = 37.0 bits (84), Expect = 0.57
Identities = 78/375 (20%), Positives = 147/375 (39%), Gaps = 53/375 (14%)
Query: 550 QGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDT 609
Q EGD + + T ++++D + +E I+ + IP P + KA+
Sbjct: 113 QPKEGDIPKAPEETIQSKKEDLPKS-SEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKP 171
Query: 610 EQGREGEATATADRREQ-------RRTEEGLKDKEDSDSMTNTTKIQ--LIHDEKRLKKE 660
Q +EG+ + Q + +EE ++ KE ++ IQ L + K K
Sbjct: 172 SQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKP 231
Query: 661 QILTEKEVATKDSKFKMPKFKMPLFGASAP-----GKSMEASVDVSAPKVEADVS----- 710
E ++ + PK ++ P G +ASV S PK E D+S
Sbjct: 232 SQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDISKSPEE 290
Query: 711 -LLSMQGDL-KTTDLSVQ--------TPSADLEVQDGQVDVKLPEGPLPEGASL------ 754
+ +GDL K+ + ++Q +P ++ ++G + L E P+ +
Sbjct: 291 AIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEE 350
Query: 755 -----KGHLPKVQRPSLKMPKVDL-KGPKLDLKGPKAEVTAPDVKMSLSSMEVDV-QAPR 807
KG +PK +++ + D+ K PK ++ PK ++ ++ E+D+ ++P
Sbjct: 351 TIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPE 409
Query: 808 AKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADV 867
+ + SL ++ +K+ P+ + F D V V K + +
Sbjct: 410 ETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEFPEG-------DKVKVILSKEDFEA 461
Query: 868 SLSSMQGDLKATDLS 882
SL L A D S
Sbjct: 462 SLKEAGERLVAVDFS 476
Score = 35.8 bits (81), Expect = 1.3
Identities = 101/447 (22%), Positives = 169/447 (37%), Gaps = 68/447 (15%)
Query: 863 VEADVSLSSMQGD-LKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEM 921
+ + S +S +GD L + + P D ++ + ++ EG +P+ + K ++
Sbjct: 75 MRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDL 134
Query: 922 PSFKMPKVDLKGPQIDVKG-----PKLDLKGPKAEV-TAPDGEVSLP-SMEVDVQAQKAK 974
P + K I PKL PKA V + E +P + E +Q++K
Sbjct: 135 PKSSEKAIQPKESNIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDIPKAPEETIQSKKED 193
Query: 975 LDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSL 1034
L + E + + D+ +K PK G K V S PK E+D+
Sbjct: 194 LPKS-SEEAIQPKEGDIPKSSAKPIQPKL----------GNIAKTSVKPSQPK-ESDIP- 240
Query: 1035 PSMQGDLKTTDLSIQPASTDL-KVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPK 1093
K+ + +IQP D+ K A + KL G++P+ A +K PK E K P+
Sbjct: 241 -------KSPEETIQPKEGDIPKSSAKPIQPKL--GNIPK-ASVKPSQPK-EGDISKSPE 289
Query: 1094 VALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDV-----EAPGAKLDSARLEGE 1148
A++ + D+ + PK E ++ E D+ EA K E
Sbjct: 290 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPE 349
Query: 1149 LSLADK--DVTAKDSRFKMPKF----KMPSFGASAPGKSIEASVDVSAPKVEADVSLPSM 1202
++ K D+ PK K P I S++ + P E D+
Sbjct: 350 ETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIP---- 405
Query: 1203 QGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK 1262
K+ + +IQP D K LE P +G + K + +++ P +
Sbjct: 406 ----KSPEETIQPKEDD--------SPKSLEEATPSK---EGDILKPEEETMEFP----E 446
Query: 1263 GPQVEVRGPKLDLKGHKAEVTAHEVAV 1289
G +V+V K D + E VAV
Sbjct: 447 GDKVKVILSKEDFEASLKEAGERLVAV 473
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapiens]
Length = 486
Score = 48.5 bits (114), Expect = 2e-04
Identities = 87/383 (22%), Positives = 162/383 (42%), Gaps = 54/383 (14%)
Query: 2016 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQTGQVD--------VKLPEGHV 2061
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E ++
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 2062 PEGAGLK-----GHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKDPKVEMRVPDVEVS 2115
P+ + G++PK + + + D+ K P+ I+ K DL E P E
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 141
Query: 2116 LPSMEVDVQAPR----AKLD---SAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAP 2168
+P P+ AK S + D+ + ++ T + + +PK
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 199
Query: 2169 GKSIEASVDVSPPKVEADMS------LPSMQGDL-KTTDLSIQPLSADVKVQAGQVDVKL 2221
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ + ++
Sbjct: 200 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQP 257
Query: 2222 LEGPVPEEV-----GLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 2274
EG +P+ + +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 258 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 317
Query: 2275 PD------VEVSLPSVEVDV-KAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLS 2327
+ +E ++P E+D+ K+P + + SL ++ +K+ P+ + +
Sbjct: 318 KEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETME 376
Query: 2328 FGVSALGKSIEASADVSALKVEA 2350
F K I + D A EA
Sbjct: 377 FPEGDKVKVILSKEDFEASLKEA 399
Score = 47.0 bits (110), Expect = 6e-04
Identities = 78/320 (24%), Positives = 136/320 (42%), Gaps = 52/320 (16%)
Query: 3666 PKVEADVSLPSMQGDLKTTDLSIQPPSADL------KVQAGQMD--------VKLPEGQV 3711
PK A+ S P K+++ +IQP D+ +Q+ + D ++ E +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 3712 PEGAGLK-----EHLPKVEMPSLKMPKVDL-KGPQVDIKGPKLDLKVSKAEVTAPDVEVS 3765
P+ + ++PK + + + D+ K P+ I+ K DL S E P E
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EGD 141
Query: 3766 LPSVEVDVQAPR----AKLD---SAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAP 3818
+P P+ AK S E D+ + ++ T + + +PK
Sbjct: 142 IPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE-TIQPKEGDIPKSSAKPIQPKL- 199
Query: 3819 GKSIEASVHVSAPKVEADVS------LPSMQGDL-KTTDLSIQPHSADLTVQARQVDMKL 3871
G +ASV S PK E D+S + +GDL K+ + +IQP D+ + ++
Sbjct: 200 GNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEA-IQP 257
Query: 3872 LEGHVP---EEA--GLKGHLPKVQMPSFKMPKVDL-KGPEIDIKGPKLDL-KDPKVEVTA 3924
EG +P EEA +G +PK + + K D+ K PE I+ + D+ K PK +
Sbjct: 258 KEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQP 317
Query: 3925 PD------VEVSLPSVEVDV 3938
+ +E ++P E+D+
Sbjct: 318 KEGDIPKSLEEAIPPKEIDI 337
Score = 44.7 bits (104), Expect = 0.003
Identities = 91/420 (21%), Positives = 166/420 (39%), Gaps = 64/420 (15%)
Query: 3570 DLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSV-EVDVQAPKAKLDAGRLEGDLSLAD 3628
DL + PK D +E + E +P E +Q+ K L E + +
Sbjct: 21 DLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSS-EKAIQPKE 79
Query: 3629 KDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDL-KTTDLS 3687
++ +K PK G +ASV S PK +GD+ K + +
Sbjct: 80 SNIPKSSAKPIQPKL----------GNIPKASVKPSQPK----------EGDIPKAPEET 119
Query: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAG--LKEHLPKVEMPSLK--MPKVD--LKGPQV 3741
IQ DL ++ + ++ EG +P+ + ++ L + S+K PK K P+
Sbjct: 120 IQSKKEDLP-KSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEE 178
Query: 3742 DIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDS 3801
I+ + D+ S A+ P + ++P V P+ S E + + D+
Sbjct: 179 TIQPKEGDIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLE 237
Query: 3802 KFKMPKF----KMPSFGVSAPGKSIEASVHVSAPKVEADV------SLPSMQGDL-KTTD 3850
+ PK K P + I S+ + E D+ ++ +GD+ K+ +
Sbjct: 238 EAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPE 297
Query: 3851 LSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKG 3910
+IQP D+ +Q ++ EG +P+ L+ +P PK EIDI
Sbjct: 298 EAIQPKEGDIPKSPKQA-IQPKEGDIPKS--LEEAIP---------PK------EIDIPK 339
Query: 3911 PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKL----DGARLEGDLSLADKDMTAKDS 3966
+ PK + + +E + PS E D+ P + +G +++ LS D + + K++
Sbjct: 340 SPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEA 399
Score = 43.5 bits (101), Expect = 0.006
Identities = 85/382 (22%), Positives = 160/382 (41%), Gaps = 52/382 (13%)
Query: 1026 PKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGA-----GLKGH 1080
PK A+ S P K+++ +IQP D+ +A + ++ + LP+ + + +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIP-KAPEETIQSKKEDLPKSSEKAIQPKESN 81
Query: 1081 LPK-----VEMPSFKMPKVALKGPQV---DV-KGPKLDLKSPKAEVTAPDVEVSLPSVEV 1131
+PK ++ +PK ++K Q D+ K P+ ++S K ++ E P E
Sbjct: 82 IPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPK-EG 140
Query: 1132 DVEAPGAKLDSARLEGELSLADKDVTAKDSRF-KMPKFKMPSFGASAP-----------G 1179
D+ AK +L + K K+S K P+ + P G
Sbjct: 141 DIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLG 200
Query: 1180 KSIEASVDVSAPKVEADVS------LPSMQGDL-KTTDLSIQPPSADLEVHAGQVDVKLL 1232
+ASV S PK E D+S + +GDL K+ + +IQP D+ + + ++
Sbjct: 201 NIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPK 258
Query: 1233 EGHVPEG-----AGFKGHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDL-KGHKAEVTAH 1285
EG +P+ +G +PK +++ K D+ K P+ ++ + D+ K K +
Sbjct: 259 EGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPK 318
Query: 1286 E------VAVSLPSVEVDM-QAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSF 1338
E + ++P E+D+ ++P + + D SL ++ +K+ P+ + F
Sbjct: 319 EGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEF 377
Query: 1339 GVSAPGKSIEASVDLSAPKVEA 1360
K I + D A EA
Sbjct: 378 PEGDKVKVILSKEDFEASLKEA 399
Score = 41.6 bits (96), Expect = 0.023
Identities = 82/391 (20%), Positives = 149/391 (38%), Gaps = 70/391 (17%)
Query: 1521 PKVEADVSLPSMQGDLKATDLSIQPPSADL------EVQAGQVDV-------------KL 1561
PK A+ S P K+++ +IQP D+ +Q+ + D+ +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 1562 PEGPVSEGAGLKGHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKVEVTAPDVKMS 1620
P+ G++PK + + + D+ K P+ ++ K DL E P
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQP----- 137
Query: 1621 LSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKF-KMPKFKMPSFGVSAP------ 1673
E D+ AK +L + K K+S K P+ + P
Sbjct: 138 ---KEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 194
Query: 1674 -----GKSIEASVDVSEPKVEADVS------LPSMQGDL-KTTDLSIQ--------SPSA 1713
G +ASV S+PK E D+S + +GDL K+ + +IQ SP
Sbjct: 195 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEE 253
Query: 1714 DLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSL--------KMPKVALKGPQMDV-K 1764
++ + G + L E P+ +G +PK ++ K P+ A++ + D+ K
Sbjct: 254 AIQPKEGDIPKSLEEAIQPK----EGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK 309
Query: 1765 GPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFK 1824
PK ++ PK + +E ++P E+D+ + + + ++ +K+
Sbjct: 310 SPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDIL 368
Query: 1825 MPKFKMPSFGVSAPGKSIEASVDVSAPKVEA 1855
P+ + F K I + D A EA
Sbjct: 369 KPEEETMEFPEGDKVKVILSKEDFEASLKEA 399
Score = 41.6 bits (96), Expect = 0.023
Identities = 68/323 (21%), Positives = 134/323 (41%), Gaps = 58/323 (17%)
Query: 3996 PKVEADVSLPSMQGDLKATDLSVQPPSADL------EVQAGQVD--------VKLPEGPV 4041
PK A+ S P K+++ ++QP D+ +Q+ + D ++ E +
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 4042 PEGASLK-----GHLPKVQMPSFKMPKVDL-KGPQIDVKGPKLDLKGPKAEVTAP---DV 4092
P+ ++ G++PK + + + D+ K P+ ++ K DL E P D+
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDI 142
Query: 4093 KMSLS-----------------SMEVDVQAPRAKLDGVQ-LEGDLSLADKDVTAKDSKFK 4134
S + S + P++ + +Q EGD+ + +AK + K
Sbjct: 143 PKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS----SAKPIQPK 198
Query: 4135 MPKFKMPSFGVSAP-----GKSMEASVDVSE--LKAKADVSLPSMQGDL-KTTDLSIQSP 4186
+ S S P KS E ++ E L + ++ +GD+ K+ + +IQ
Sbjct: 199 LGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK 258
Query: 4187 SADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDV-KGPKLDL 4245
D+ + ++ EG +PK K +P K P+ A++ + D+ K PK +
Sbjct: 259 EGDIPKSLEEA-IQPKEGDIPKSPEETIQPKKGDIP--KSPEEAIQPKEGDIPKSPKQAI 315
Query: 4246 KGPKADVMTPVVEVSLPSMEVDV 4268
+ PK + +E ++P E+D+
Sbjct: 316 Q-PKEGDIPKSLEEAIPPKEIDI 337
Score = 40.4 bits (93), Expect = 0.052
Identities = 84/401 (20%), Positives = 158/401 (39%), Gaps = 64/401 (15%)
Query: 1191 PKVEADVSLPSMQGDLKTTDLSIQPPSADLE--------------VHAGQVDVKLLEGHV 1236
PK A+ S P K+++ +IQP D+ + + ++ E ++
Sbjct: 23 PKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNI 82
Query: 1237 PEGAGFK-----GHLPKVQMPSLKMPKVDL-KGPQVEVRGPKLDLKGHKAEVTAHEVAVS 1290
P+ + G++PK + + + D+ K P+ ++ K DL E +
Sbjct: 83 PKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE--------A 134
Query: 1291 LPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKF-KMPKFKMPSFGVSAP------ 1343
+ E D+ AK +L + K K+S K P+ + P
Sbjct: 135 IQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKP 194
Query: 1344 -----GKSIEASVDLSAPKVEADMS------LPSMQGDL-KTTDLSIQPPSTDLELQAGQ 1391
G +ASV S PK E D+S + +GDL K+ + +IQP D+ ++ +
Sbjct: 195 IQPKLGNIPKASVKPSQPK-EGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPE 252
Query: 1392 LDVKLPEGPVPEG-----AGLKGHLPKLQMPSFKVPKVDL-KGPEIDIKGPKLDL-KDPK 1444
++ EG +P+ +G +PK + + K D+ K PE I+ + D+ K PK
Sbjct: 253 EAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPK 312
Query: 1445 VEVTAPD------VEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKF 1498
+ + +E ++P E+D+ + + ++ ++ +K+ P+
Sbjct: 313 QAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEE 372
Query: 1499 KMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKAT 1539
+ F K I + D A EA L ++ D AT
Sbjct: 373 ETMEFPEGDKVKVILSKEDFEASLKEAGERLVAV--DFSAT 411
Score = 37.0 bits (84), Expect = 0.57
Identities = 78/375 (20%), Positives = 147/375 (39%), Gaps = 53/375 (14%)
Query: 550 QGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDT 609
Q EGD + + T ++++D + +E I+ + IP P + KA+
Sbjct: 46 QPKEGDIPKAPEETIQSKKEDLPKS-SEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKP 104
Query: 610 EQGREGEATATADRREQ-------RRTEEGLKDKEDSDSMTNTTKIQ--LIHDEKRLKKE 660
Q +EG+ + Q + +EE ++ KE ++ IQ L + K K
Sbjct: 105 SQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKP 164
Query: 661 QILTEKEVATKDSKFKMPKFKMPLFGASAP-----GKSMEASVDVSAPKVEADVS----- 710
E ++ + PK ++ P G +ASV S PK E D+S
Sbjct: 165 SQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDISKSPEE 223
Query: 711 -LLSMQGDL-KTTDLSVQ--------TPSADLEVQDGQVDVKLPEGPLPEGASL------ 754
+ +GDL K+ + ++Q +P ++ ++G + L E P+ +
Sbjct: 224 AIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEE 283
Query: 755 -----KGHLPKVQRPSLKMPKVDL-KGPKLDLKGPKAEVTAPDVKMSLSSMEVDV-QAPR 807
KG +PK +++ + D+ K PK ++ PK ++ ++ E+D+ ++P
Sbjct: 284 TIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQ-PKEGDIPKSLEEAIPPKEIDIPKSPE 342
Query: 808 AKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADV 867
+ + SL ++ +K+ P+ + F D V V K + +
Sbjct: 343 ETIQPKEDDSPKSL-EEATPSKEGDILKPEEETMEFPEG-------DKVKVILSKEDFEA 394
Query: 868 SLSSMQGDLKATDLS 882
SL L A D S
Sbjct: 395 SLKEAGERLVAVDFS 409
Score = 35.8 bits (81), Expect = 1.3
Identities = 101/447 (22%), Positives = 169/447 (37%), Gaps = 68/447 (15%)
Query: 863 VEADVSLSSMQGD-LKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEM 921
+ + S +S +GD L + + P D ++ + ++ EG +P+ + K ++
Sbjct: 8 MRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDL 67
Query: 922 PSFKMPKVDLKGPQIDVKG-----PKLDLKGPKAEV-TAPDGEVSLP-SMEVDVQAQKAK 974
P + K I PKL PKA V + E +P + E +Q++K
Sbjct: 68 PKSSEKAIQPKESNIPKSSAKPIQPKLG-NIPKASVKPSQPKEGDIPKAPEETIQSKKED 126
Query: 975 LDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSL 1034
L + E + + D+ +K PK G K V S PK E+D+
Sbjct: 127 LPKS-SEEAIQPKEGDIPKSSAKPIQPKL----------GNIAKTSVKPSQPK-ESDIP- 173
Query: 1035 PSMQGDLKTTDLSIQPASTDL-KVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPK 1093
K+ + +IQP D+ K A + KL G++P+ A +K PK E K P+
Sbjct: 174 -------KSPEETIQPKEGDIPKSSAKPIQPKL--GNIPK-ASVKPSQPK-EGDISKSPE 222
Query: 1094 VALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDV-----EAPGAKLDSARLEGE 1148
A++ + D+ + PK E ++ E D+ EA K E
Sbjct: 223 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPE 282
Query: 1149 LSLADK--DVTAKDSRFKMPKF----KMPSFGASAPGKSIEASVDVSAPKVEADVSLPSM 1202
++ K D+ PK K P I S++ + P E D+
Sbjct: 283 ETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIP---- 338
Query: 1203 QGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK 1262
K+ + +IQP D K LE P +G + K + +++ P +
Sbjct: 339 ----KSPEETIQPKEDD--------SPKSLEEATPSK---EGDILKPEEETMEFP----E 379
Query: 1263 GPQVEVRGPKLDLKGHKAEVTAHEVAV 1289
G +V+V K D + E VAV
Sbjct: 380 GDKVKVILSKEDFEASLKEAGERLVAV 406
>gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens]
Length = 149
Score = 47.4 bits (111), Expect = 4e-04
Identities = 24/89 (26%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Query: 105 EAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTV 164
E + E+ L +G+ G ++ D G+FV++V ++S AA+ ++EGDQ++ T+
Sbjct: 2 EKEETTRELLLPNWQGSGSHGLTIAQR-DDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60
Query: 165 FFENIKYEDALKILQYSEPYKVQFKIRRQ 193
+F+N++ + ++L + V K+ R+
Sbjct: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRK 89
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 47.0 bits (110), Expect = 6e-04
Identities = 228/1104 (20%), Positives = 361/1104 (32%), Gaps = 190/1104 (17%)
Query: 440 AQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTE 499
A P PG GEGE + + LS TEG + FAF
Sbjct: 340 ADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDE----------------AFAF--- 380
Query: 500 KEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDE-GDGEE 558
R D S+ + + ++AEA + GE
Sbjct: 381 ----------------RDDTSAASSDS---------------DSASYAEADDERLYSGEP 409
Query: 559 GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEAT 618
Q T + + K E++ G + + + ++ W+ +T A Q E
Sbjct: 410 HAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEV- 468
Query: 619 ATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMP 678
TEEGL ++S + +Q+ + ++ + DS
Sbjct: 469 ----------TEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQE 518
Query: 679 KFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQ 738
M + P S E ++ + V+ + + T L++ S ++G
Sbjct: 519 SAAMAM-----PQPSQEGISEILG---QESVTAEKLPTPQEETSLTLCPDSPQNLKEEGG 570
Query: 739 VDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLK------GPK----AEVT 788
+D LP G P A+ +P+ + L +P+ P L L+ PK A +
Sbjct: 571 LD--LPSGRKPVAAAT--IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 626
Query: 789 APDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKD--SKFKMPKFKMPSFGVS 846
+ + L+ + V P L + +LS A K V A S+ +P
Sbjct: 627 SQQAEEGLTLPQDSVMTPPLPLQ----DTELSSAPKPVAAATLVSQQAEEGLTLPQDSAM 682
Query: 847 APGKSMEDSVDVSAPKVEADVSLSSMQGDLKAT---DLSIQPPSADLEVQAGQVDVKLPE 903
P ++D+ SAPK A +L S Q + T D ++ PP L +Q D L
Sbjct: 683 TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP---LPLQ----DTDLSS 735
Query: 904 GPVPEGAGPKVH--------LPK--VEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVT 953
P P A V LP+ P + DL V + + + +T
Sbjct: 736 APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT 795
Query: 954 APDGEV---SLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGV 1010
P LP + D+ + + A + A++ +T P + +
Sbjct: 796 LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS--QQAEEGLTLPQDSAMTPPLPLQDTDL 853
Query: 1011 SAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGH 1070
S+ K + A VS + E L+LP Q T L +Q T + + V P+
Sbjct: 854 SSAPKPVAAATPVS-QQAEEGLTLP--QDSAMTAPLPLQ--DTGPTSGPEPLAVATPQTL 908
Query: 1071 LPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVE 1130
E G P M ++ + P + K L T P+ +L V+
Sbjct: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALP--------TVPE-PAALDQVQ 959
Query: 1131 VDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSA 1190
D P A+ G A +D DS M +P A G E + +S
Sbjct: 960 QDDPQPAAE------AGTPWAAQEDA---DSTLGMEALSLPE---PASGAGEEIAEALSR 1007
Query: 1191 PKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVD--VKLLEGHVPEGAGFKGHLPK 1248
P EA + + GD D P LEV Q L + H P A G
Sbjct: 1008 PGREACLEARAHTGDGAKPD---SPQKETLEVENQQEGGLKPLAQEHGPRSA-LGGAREV 1063
Query: 1249 VQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGA 1308
P P+V Q + P + +G + T S + E + + GA
Sbjct: 1064 PDAPPAACPEVS----QARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA 1119
Query: 1309 QLDGDLSLADKDVTAKDSKFKMPK-----------FKMPS------------FGVSAPGK 1345
D D + P+ ++PS P
Sbjct: 1120 VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPST 1179
Query: 1346 SIEASV--DLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPE-GPVP 1402
++ + D SAP A +LP ++ Q S + E G L + P+ G P
Sbjct: 1180 PVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQP 1239
Query: 1403 EGAGLKGHLPKLQMPSFKVPKVDLK--GPEIDIKGPKLDLKD------PKVEVTAPDVEV 1454
A + G P P+V L P + K +D KD P +V P
Sbjct: 1240 AAAAVSG----TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQ 1295
Query: 1455 SLPSVEVDVEAPGAKLDGGRLEED 1478
S P+ + AP + D LEED
Sbjct: 1296 S-PAGPQGLSAPEQQEDEDSLEED 1318
>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 47.0 bits (110), Expect = 6e-04
Identities = 228/1104 (20%), Positives = 361/1104 (32%), Gaps = 190/1104 (17%)
Query: 440 AQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTE 499
A P PG GEGE + + LS TEG + FAF
Sbjct: 340 ADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDE----------------AFAF--- 380
Query: 500 KEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDE-GDGEE 558
R D S+ + + ++AEA + GE
Sbjct: 381 ----------------RDDTSAASSDS---------------DSASYAEADDERLYSGEP 409
Query: 559 GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEAT 618
Q T + + K E++ G + + + ++ W+ +T A Q E
Sbjct: 410 HAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEV- 468
Query: 619 ATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMP 678
TEEGL ++S + +Q+ + ++ + DS
Sbjct: 469 ----------TEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQE 518
Query: 679 KFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQ 738
M + P S E ++ + V+ + + T L++ S ++G
Sbjct: 519 SAAMAM-----PQPSQEGISEILG---QESVTAEKLPTPQEETSLTLCPDSPQNLKEEGG 570
Query: 739 VDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLK------GPK----AEVT 788
+D LP G P A+ +P+ + L +P+ P L L+ PK A +
Sbjct: 571 LD--LPSGRKPVAAAT--IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 626
Query: 789 APDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKD--SKFKMPKFKMPSFGVS 846
+ + L+ + V P L + +LS A K V A S+ +P
Sbjct: 627 SQQAEEGLTLPQDSVMTPPLPLQ----DTELSSAPKPVAAATLVSQQAEEGLTLPQDSAM 682
Query: 847 APGKSMEDSVDVSAPKVEADVSLSSMQGDLKAT---DLSIQPPSADLEVQAGQVDVKLPE 903
P ++D+ SAPK A +L S Q + T D ++ PP L +Q D L
Sbjct: 683 TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP---LPLQ----DTDLSS 735
Query: 904 GPVPEGAGPKVH--------LPK--VEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVT 953
P P A V LP+ P + DL V + + + +T
Sbjct: 736 APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT 795
Query: 954 APDGEV---SLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGV 1010
P LP + D+ + + A + A++ +T P + +
Sbjct: 796 LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS--QQAEEGLTLPQDSAMTPPLPLQDTDL 853
Query: 1011 SAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGH 1070
S+ K + A VS + E L+LP Q T L +Q T + + V P+
Sbjct: 854 SSAPKPVAAATPVS-QQAEEGLTLP--QDSAMTAPLPLQ--DTGPTSGPEPLAVATPQTL 908
Query: 1071 LPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVE 1130
E G P M ++ + P + K L T P+ +L V+
Sbjct: 909 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALP--------TVPE-PAALDQVQ 959
Query: 1131 VDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSA 1190
D P A+ G A +D DS M +P A G E + +S
Sbjct: 960 QDDPQPAAE------AGTPWAAQEDA---DSTLGMEALSLPE---PASGAGEEIAEALSR 1007
Query: 1191 PKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVD--VKLLEGHVPEGAGFKGHLPK 1248
P EA + + GD D P LEV Q L + H P A G
Sbjct: 1008 PGREACLEARAHTGDGAKPD---SPQKETLEVENQQEGGLKPLAQEHGPRSA-LGGAREV 1063
Query: 1249 VQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGA 1308
P P+V Q + P + +G + T S + E + + GA
Sbjct: 1064 PDAPPAACPEVS----QARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA 1119
Query: 1309 QLDGDLSLADKDVTAKDSKFKMPK-----------FKMPS------------FGVSAPGK 1345
D D + P+ ++PS P
Sbjct: 1120 VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPST 1179
Query: 1346 SIEASV--DLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPE-GPVP 1402
++ + D SAP A +LP ++ Q S + E G L + P+ G P
Sbjct: 1180 PVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQP 1239
Query: 1403 EGAGLKGHLPKLQMPSFKVPKVDLK--GPEIDIKGPKLDLKD------PKVEVTAPDVEV 1454
A + G P P+V L P + K +D KD P +V P
Sbjct: 1240 AAAAVSG----TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQ 1295
Query: 1455 SLPSVEVDVEAPGAKLDGGRLEED 1478
S P+ + AP + D LEED
Sbjct: 1296 S-PAGPQGLSAPEQQEDEDSLEED 1318
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 46.6 bits (109), Expect = 7e-04
Identities = 117/570 (20%), Positives = 196/570 (34%), Gaps = 74/570 (12%)
Query: 1110 LKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFK 1169
+++P + T P ++V ++AP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 1170 MPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDV 1229
AS S AS +P ++A +SLP+ + ++ P S+ L +H Q +
Sbjct: 437 TQ---ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA-L 492
Query: 1230 KLLEGHVPEGAGFKGHLPKVQM------PSLKMPKVDLKGPQVEVRGPKL---DLKGHKA 1280
L H P+ +P ++ PSL+ P L P +E P L L+ A
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASA 551
Query: 1281 EVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGV 1340
+T + +QAP + L + S+A A + P +PS +
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 1341 SAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGP 1400
S + P+ ++LP +Q PPS L P+ P
Sbjct: 612 S--------PLATPPPQAPPXLALPPLQA----------PPSPPASPPLSPLATPSPQAP 653
Query: 1401 VPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVE 1460
L HL LQ P P ++ P P + P ++ P ++
Sbjct: 654 ----NALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP--SLAAPPLQ 705
Query: 1461 VDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSA 1520
V P + MS + P ++P ++P S A+
Sbjct: 706 VPPSPPAS--------PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 1521 PKVEADVSL---PSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLP 1577
P + A L PS L + L+ PP A + + LP P S G P
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA-LPSPPAS-FPGQAPFSP 815
Query: 1578 KVQMPSFKMPKVDLKGPQIDVKGPKLDL------------------KGPKVEVTAPDVKM 1619
+P + + P + + P L + GP V+ P + +
Sbjct: 816 SASLPMSPLATPPPQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 1620 SLS--SMEVDVQAPRAKLDGAQLEGDLSLA 1647
+L+ ++P + L G L G S A
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Score = 45.4 bits (106), Expect = 0.002
Identities = 59/261 (22%), Positives = 103/261 (39%), Gaps = 33/261 (12%)
Query: 1935 LKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFK 1994
++ P + T P ++V +QA + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 1995 MPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDV 2054
+++P R AS +P ++A +SLP+ + ++ P S+ L + Q
Sbjct: 436 QTQASLTSPSRP--ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL- 492
Query: 2055 KLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEV 2114
+ L H P+ + SL MP ++ Q + P L + P + P +E
Sbjct: 493 ----------SSLASHSPQAPLSSLIMPPLET---QSSLAPPSL--QTPPASLTTPPLE- 536
Query: 2115 SLPSMEVD-VQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIE 2173
+LPS+ +Q A L + HL+ A L S P + PS
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS----------- 585
Query: 2174 ASVDVSPPKVEADMSLPSMQG 2194
S+ PP+ ++ P +QG
Sbjct: 586 -SIATPPPQAPPALASPPLQG 605
Score = 44.7 bits (104), Expect = 0.003
Identities = 53/246 (21%), Positives = 93/246 (37%), Gaps = 32/246 (13%)
Query: 3585 LKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFK 3644
++ P + +P ++V +QAP + L L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 3645 MPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDV 3704
+ S S AS +P ++A +SLP+ + ++ P S+ L + Q
Sbjct: 437 T---QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL- 492
Query: 3705 KLPEGQVPEGAGLKEHLPKVEMPSLKMPKVD---------LKGPQVDIKGPKLD------ 3749
+ L H P+ + SL MP ++ L+ P + P L+
Sbjct: 493 ----------SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 3750 ---LKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMP 3806
L+ + A +T P +E +QAP + L + E S+A A + P
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 3807 KFKMPS 3812
+PS
Sbjct: 603 LQGLPS 608
Score = 44.3 bits (103), Expect = 0.004
Identities = 70/316 (22%), Positives = 120/316 (37%), Gaps = 42/316 (13%)
Query: 3420 LKVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFK 3479
++ P + T+P ++V +QAP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 3480 MPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDV 3539
+++P R AS +P ++A +SL + + ++ P S+ L +
Sbjct: 436 QTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH------ 487
Query: 3540 ELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEV 3599
P+ + L H P+ + SL P ++ Q + P L+ P A + P +E
Sbjct: 488 -----PLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPPLE- 536
Query: 3600 SLPSV-EVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSME 3658
+LPS+ +Q A L LE A + A S P + PS
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS----------- 585
Query: 3659 ASVDVSAPKVEADVSLPSMQG--DLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAG 3716
S+ P+ ++ P +QG + L+ PP A + LP Q P
Sbjct: 586 -SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA-------PPXLALPPLQAPPSPP 637
Query: 3717 LKEHLPKVEMPSLKMP 3732
L + PS + P
Sbjct: 638 ASPPLSPLATPSPQAP 653
Score = 44.3 bits (103), Expect = 0.004
Identities = 60/269 (22%), Positives = 105/269 (39%), Gaps = 35/269 (13%)
Query: 3758 TAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSA 3817
T P ++V +QAP + L + L+ SL + A S M + +++
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-RQTQASLTS 443
Query: 3818 PGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVP 3877
P + AS +P ++A +SLP+ + ++ P S+ LT+ Q
Sbjct: 444 PSRP--ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA---------- 491
Query: 3878 EEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSV-EV 3936
+ L H P+ + S MP ++ + + P L+ P +T P +E +LPS+
Sbjct: 492 -LSSLASHSPQAPLSSLIMPPLETQS---SLAPP--SLQTPPASLTTPPLE-NLPSLAPP 544
Query: 3937 DVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAP 3996
++ A L LE A + A S P + PS S+ P
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS------------SIATPPP 592
Query: 3997 KVEADVSLPSMQG--DLKATDLSVQPPSA 4023
+ ++ P +QG + L+ PP A
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQA 621
Score = 43.1 bits (100), Expect = 0.008
Identities = 81/313 (25%), Positives = 106/313 (33%), Gaps = 44/313 (14%)
Query: 4735 PLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTK 4794
PLSS E Q S+ + PS+Q P P L P + +P T
Sbjct: 503 PLSSLIMPPLETQ--SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT----TP 556
Query: 4795 YQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIP 4854
+ T P A P L+ P S P P+T S PP+ P S PL +
Sbjct: 557 HLETPPCPAPCP---LQAPP-SPLTTPPPETPSSIATPPPQAPPALA----SPPLQGLPS 608
Query: 4855 VSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSP 4914
L ++ P P P +A+P + AP P SP PL PSP
Sbjct: 609 PPLSPLATPPPQAP------PXLALPP------LQAPPSPPASP------PLSPLATPSP 650
Query: 4915 GTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPK 4974
Q P L L + +P +P A SP P PS + P P
Sbjct: 651 -----QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-QAPPSLAAPPL 704
Query: 4975 VDPECSVEDSKLSLVLDKDEVAPQ--SAIHMDLPPERDGEKGRS---TKPGFAMPKLALP 5029
P +S AP +A + +PP S T P P LA P
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 5030 KMKASKS-GVSLP 5041
++ S SLP
Sbjct: 765 PLQVPPSPPASLP 777
Score = 42.0 bits (97), Expect = 0.018
Identities = 54/232 (23%), Positives = 90/232 (38%), Gaps = 19/232 (8%)
Query: 3923 TAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSA 3982
T P ++V ++AP + L + L+ SL + A S M + + S
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA---SL 441
Query: 3983 PGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVP 4042
S AS +P ++A +SLP+ + +V P S+ L + P+
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH-----------PLQ 490
Query: 4043 EGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSMEVD 4102
+SL H P+ + S MP ++ Q + P L+ P A +T P ++ S
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPPLENLPSLAPPP 545
Query: 4103 VQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEA 4154
+Q A L LE A + A S P + PS + P ++ A
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597
Score = 40.0 bits (92), Expect = 0.067
Identities = 72/319 (22%), Positives = 117/319 (36%), Gaps = 48/319 (15%)
Query: 1605 LKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFK 1664
++ P T P +++ S +QAP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 1665 MPSFGVSAPGKSIEASVDVSEPKVEADVSLPS---MQGDLKTTDLSIQSPSADLEVQAGQ 1721
+++P + AS P ++A +SLP+ +Q L + SP
Sbjct: 436 QTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP---------- 483
Query: 1722 VNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPD 1781
L PL + H P+ + SL MP + Q + P L+ P A + P
Sbjct: 484 ----LTIHPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPP 534
Query: 1782 VEVSLPSV-EVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGK 1840
+E +LPS+ ++ A L + LE A + A S P + PS
Sbjct: 535 LE-NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS-------- 585
Query: 1841 SIEASVDVSAPKVEAEVSLPSMQG--DLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPE 1898
S+ P+ ++ P +QG + L P P A + LP Q P
Sbjct: 586 ----SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA-------PPXLALPPLQAPP 634
Query: 1899 GAGLKGHLPKVDMPSFKMP 1917
L + PS + P
Sbjct: 635 SPPASPPLSPLATPSPQAP 653
Score = 37.0 bits (84), Expect = 0.57
Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 20/185 (10%)
Query: 2100 LKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFK 2159
++ P +P ++V +QAP + L + LQ +L + L S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 2160 MPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDV 2219
+++P + AS P ++A +SLP+ + ++ PLS+ + +
Sbjct: 436 QTQASLTSPSRP--ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH------ 487
Query: 2220 KLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEV 2279
P+ L H P+ + S +P ++ + + P L+ P +T P +E
Sbjct: 488 -----PLQALSSLASHSPQAPLSSLIMPPLETQS---SLAPP--SLQTPPASLTTPPLE- 536
Query: 2280 SLPSV 2284
+LPS+
Sbjct: 537 NLPSL 541
Score = 36.2 bits (82), Expect = 0.97
Identities = 82/365 (22%), Positives = 116/365 (31%), Gaps = 47/365 (12%)
Query: 4844 SHSGPLNSMIPVSLGQVSFPKFYKPKFVFSV--PQMAVPEGDLHAAVGAPVMSPLS---- 4897
+ SGP P + S PK PK + ++ PQ+ P D A+G SPL+
Sbjct: 253 ARSGPSARGTPRAPAHPSQPK---PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 4898 ---------PGERVQCPLPSTQLPSP--GTCVSQGPEELVA--SLQTSVVAPGEAPSE-- 4942
P + PLP+T PSP T + P A SLQT P PS+
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 4943 ----DADHEGKGSPLKMPKIKLPSFRWSPKKETGP------KVDPECSVEDSKLSLVLDK 4992
+ S +P I++P SP + P + S+ L
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 4993 DEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKL-ALPKMKASKSGVSLPQRDVDPSLSS 5051
++P+ P R + P A L A P ++ S S P LSS
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP-------LSS 482
Query: 5052 ATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKV 5111
Q +S + L + +L P + P P L + +
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 5112 EVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVL 5171
A PL L T C P+ P P PE P + P A
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPC-----PLQAPPSPLTTPPPETPSSIATPPPQAPPA 597
Query: 5172 TVESP 5176
P
Sbjct: 598 LASPP 602
Score = 36.2 bits (82), Expect = 0.97
Identities = 54/236 (22%), Positives = 90/236 (38%), Gaps = 23/236 (9%)
Query: 4080 LKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFK 4139
++ P + T P +++ S +QAP + L L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 4140 MPSFGVSAPGKSMEASVDVSELKAKADV-SLPSMQGDLKTTDLSIQSPSADLEVQAGQVD 4198
+++P + D L+A + + P +Q L + SP
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP------------ 483
Query: 4199 VKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVE 4258
L PL + L H P+ + L MP + Q + P L+ P A + TP +E
Sbjct: 484 --LTIHPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPPLE 536
Query: 4259 VSLPSM-EVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAP 4313
+LPS+ ++ A L + LE A + A S P + PS + P
Sbjct: 537 -NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591
Score = 35.8 bits (81), Expect = 1.3
Identities = 53/260 (20%), Positives = 96/260 (36%), Gaps = 31/260 (11%)
Query: 2925 LKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFK 2984
++ P + T P ++V ++AP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 2985 MPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDL 3044
+++P + D +P ++A +SLP+ + ++ P S+ L + Q
Sbjct: 436 QTQASLTSPSRPASTPPD--SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA-- 491
Query: 3045 KLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEV 3104
+ L H P+ + S MP ++ Q + P L+ P +T P +E
Sbjct: 492 ---------LSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPPLEN 537
Query: 3105 SQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEV 3164
++ A L LE A + A S P + PS + P
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP------ 591
Query: 3165 LVDVSAPKVEADLSLPSMQG 3184
P+ L+ P +QG
Sbjct: 592 ------PQAPPALASPPLQG 605
Score = 35.4 bits (80), Expect = 1.7
Identities = 54/242 (22%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 780 LKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFK 839
++ P + T P +++ S +QAP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 840 MPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDV 899
+++P + D +P ++A +SL + + ++ P S+ L +
Sbjct: 436 QTQASLTSPSRPASTPPD--SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH------ 487
Query: 900 KLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEV 959
P+ + H P+ + S MP ++ Q + P L+ P A +T P E
Sbjct: 488 -----PLQALSSLASHSPQAPLSSLIMPPLE---TQSSLAPP--SLQTPPASLTTPPLE- 536
Query: 960 SLPSM-EVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIK 1018
+LPS+ +Q A L LE A + A S P + PS + P ++
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 1019 AL 1020
AL
Sbjct: 597 AL 598
Score = 34.7 bits (78), Expect = 2.8
Identities = 51/234 (21%), Positives = 89/234 (38%), Gaps = 19/234 (8%)
Query: 2595 LKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFK 2654
++ P + T P +++ S +QAP + L + L+ SL + A S M +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-R 435
Query: 2655 MPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDV 2714
+++P D L +A +SLP+ + ++ P S+ L + Q
Sbjct: 436 QTQASLTSPSRPASTPPDSPPL--QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA-- 491
Query: 2715 KLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKM 2774
+ L H P+ + S MP ++ Q + P+ L+ P A +T P ++
Sbjct: 492 ---------LSSLASHSPQAPLSSLIMPPLE---TQSSLAPPS--LQTPPASLTTPPLEN 537
Query: 2775 SLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAP 2828
S +Q A L LE A + A S P + PS + P
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591
Score = 34.3 bits (77), Expect = 3.7
Identities = 48/235 (20%), Positives = 82/235 (34%), Gaps = 17/235 (7%)
Query: 693 SMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDG----QVDVKLPEGPL 748
S++A+ + +P ++A S L+M + T S+ +PS Q + LP P
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSP--RQTQASLTSPSRPASTPPDSPPLQAPLSLPASP- 467
Query: 749 PEGASLKGHLPKVQRPSLKMPKVDLKG-PKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPR 807
P SL + + P P L + P + + P ++ S +Q P
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
Query: 808 AKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADV 867
A L LE SLA + + P + P P ++ + P+ + +
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 868 SLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMP 922
+ Q P A +Q P P A P + LP ++ P
Sbjct: 588 ATPPPQA---------PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
sapiens]
Length = 306
Score = 46.6 bits (109), Expect = 7e-04
Identities = 62/303 (20%), Positives = 108/303 (35%), Gaps = 42/303 (13%)
Query: 189 KIRRQLPAPQDEEWASSDA------QHGPQGKEKEDTDVADGCRETPTKTLEG--DGDQE 240
++R+ + + ++W ++ Q PQ + T G +P+ +G D ++E
Sbjct: 11 RLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEE 70
Query: 241 RLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDT 300
+ RG ++++ + P+ + G G +R SS + + + A D +
Sbjct: 71 AAAAPAPTSRGHRTEKRK---PQQPQRRPAGGTGQRRGSRSSSSADQQGAQDREEEAAAA 127
Query: 301 EAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELG 360
A + + +K P + R R GSG PS+ Q + + A V G
Sbjct: 128 PAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQRAQDREEEATAAPVPTSSG 187
Query: 361 --------------PWGDSLEETGA----------ATGSRREERAEQDREVMPAQSMPLP 396
P G + + G+ TG RR R+ + AQ
Sbjct: 188 HRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRGSRSSPSADQQRAQDREEE 247
Query: 397 TELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQ 456
R GT Q G AA + GQ + TA A P P + G+ G +
Sbjct: 248 AAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRRGTAAA-------PAPTSTGTGQRRGSE 300
Query: 457 SLE 459
+E
Sbjct: 301 EME 303
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 46.6 bits (109), Expect = 7e-04
Identities = 109/476 (22%), Positives = 174/476 (36%), Gaps = 71/476 (14%)
Query: 4734 IPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLT 4793
IP + +S + +S P+ + + G A S+ DLT P L +
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAA--TPSKGDLTPPAVTPVSLKKAPATSAP 1452
Query: 4794 KYQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQP---------------PEGVP 4838
K P + P L P S + P PK + +T P P +P
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPP-SPKEPPAPK-QVATSSSPKKAPATPAPMGAPTLPAVIP 1510
Query: 4839 TSQAESHSGPLNSMIPVS----LGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMS 4894
+S E + P + P++ L P PK P M VP A+ P +
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 4895 PLSPGERVQCPLPSTQLPSPGTCV-SQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPL 4953
P +P + P+ +P T + P+EL+ + +P EAP+ A SP
Sbjct: 1571 PATPSSKEASSPPAV---TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA--VTPPSPE 1625
Query: 4954 KMPKIKLPSFRWSPKKETGPKVDPECSVED---SKLSLVLDKDEVAPQSAIHMDLPPERD 5010
K P P + +P T P V P S++D S S+ PQ++
Sbjct: 1626 KGPATPAP--KGTP---TSPPVTPS-SLKDSPTSPASVTCKMGATVPQAS---------- 1669
Query: 5011 GEKGRSTKPG-FAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGG 5069
KG K G A+ ++ + S ++ P R P ++A + ++ +G
Sbjct: 1670 --KGLPAKKGPTALKEVLVAPAPESTPIITAPTRK-GPQTKKSSATSPPICPDPSAKNGS 1726
Query: 5070 RGGLGATASA------TGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKVEVSQPEADLPLP 5123
+G L A A S + H P A P+ SKA ++ + LP
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE---SKASTPLTAAAFEKVLP 1783
Query: 5124 KHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCR-KPDAEVLTVESPEE 5178
K + ++ PVS P +AP+P L P + P + L +ESP +
Sbjct: 1784 KPESASVS-----AAPSPPVSLP----LAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830
Score = 45.8 bits (107), Expect = 0.001
Identities = 127/555 (22%), Positives = 180/555 (32%), Gaps = 78/555 (14%)
Query: 4709 VSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECS-------SFELQQVSACSEPSMQMPK 4761
VS + + P G + IG + P+S E S SF+ + S + S P
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 4762 VGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAA-------LAPELALEIPS 4814
A PS+ L+ + L P E T + + P+ AP L++ S
Sbjct: 861 PKGAPTPSAVTPLSP---KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917
Query: 4815 GSQADI-PLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFS 4873
+A P PK ++ P+G PT A + P S P P
Sbjct: 918 PKKARATPAPKGIPASP--SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 4874 VPQMAVPEG---DLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQ 4930
P P+G A +P P +P + P+ PSP + P AS
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 4931 TSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVL 4990
+ P S A KG+P P LPS + P P +
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGP---ATPSL--------------- 1076
Query: 4991 DKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLS 5050
K P +A PP G + G MP A P + K G++ P P+
Sbjct: 1077 -KGAPTPPAA----TPPSPKGGPATPSPKGAPMPPAATP--PSPKGGLATPPHKGAPTTP 1129
Query: 5051 SAT----AGG-------SFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGF 5099
+AT GG T A+ +GGL AT G+ P P G
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPP--SPKGGL 1186
Query: 5100 AKPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPED-P 5158
A P + + + P A P PK L+T P G P+P+ P
Sbjct: 1187 ATPSPKGAP-----TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 5159 LQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQT 5218
P+ P + P + A T P PSL+ G A
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTP---------PAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 5219 QAPAATGGEAAAKVK 5233
P+ GG A + K
Sbjct: 1293 TPPSPKGGPATSPPK 1307
Score = 40.0 bits (92), Expect = 0.067
Identities = 135/620 (21%), Positives = 201/620 (32%), Gaps = 107/620 (17%)
Query: 4813 PSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGP-----LNSMIPVSLGQVSFPKFYK 4867
P+ A P PK T PP+G PT A + P L + P S G + P
Sbjct: 1310 PTPPAATPPSPKGSPGTP--PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP---- 1363
Query: 4868 PKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVA 4927
S + P + G P M+P SP P P SP
Sbjct: 1364 -----SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI---------- 1408
Query: 4928 SLQTSVVAPGEAPSEDADHEGKGSP----LKMPKIKLPSFRWSPKKETGPKVDP--ECSV 4981
++P +AP+ EG +P L P + S + +P + PK P S
Sbjct: 1409 -----PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP-ATSAPKGGPATPSSK 1462
Query: 4982 EDSKLSLVL---DKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGV 5038
D L V K+ AP+ P +K +T P L + K
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSP-----KKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 5039 SLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLG 5098
+ P DP +AT L AT + L P + +PS
Sbjct: 1518 ATPSSRRDPIAPTATL------------------LSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 5099 FAKPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDP 5158
+A S EA P + +G L P APTP
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV 1619
Query: 5159 LQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQT 5218
PS K A +P +T S + P+ S + GA + A
Sbjct: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKD--------SPTSPASVTCKMGA-TVPQASK 1670
Query: 5219 QAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGL 5278
PA G A +KE LV+ + E+ + P T S +S I G
Sbjct: 1671 GLPAKKGPTA---LKEVLVAPA-PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726
Query: 5279 KLHLSTAG------MTGDELSTSEVR--IHPSKGPLPFQMPGMRLPETQVLPGEIDETPL 5330
K LST + D T++ + H KGPL PE++ TPL
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL-------APPESKA------STPL 1773
Query: 5331 SKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLM 5390
+ + + ++ S+ P P+ L + + +P+ L P L+
Sbjct: 1774 TAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT---------LPPKQQFLPSSPGLV 1824
Query: 5391 VPRFSFPAPSSEDDVFIPTV 5410
+ S P +++D +P +
Sbjct: 1825 LESPSKPLAPADEDELLPLI 1844
Score = 35.0 bits (79), Expect = 2.2
Identities = 141/634 (22%), Positives = 210/634 (33%), Gaps = 71/634 (11%)
Query: 720 TTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGA--SLKGHLPKVQRPSLKMPKVDLKGPK 777
T L TPS+ + G EGP P A S KG P + PS K +GP
Sbjct: 1346 TPTLPATTPSS----KGGPTTPSSKEGPTPPAATPSHKGG-PAMTPPSPK------RGPA 1394
Query: 778 LDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPK 837
+ PK + T+P V + LS + A +GA L VT K K P
Sbjct: 1395 IP--SPKGDPTSPAV-IPLSPKKAP--ATPVTREGAATPSKGDLTPPAVTPVSLK-KAPA 1448
Query: 838 FKMPSFGVSAPGKSMEDSVDV------SAPKVEADVSLSSMQGDLKATDLSIQPPSADLE 891
P G + P + ++ P V+ SS AT + P+
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
Query: 892 VQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLD--LKGPK 949
+ + +V + P L + P+ PK L P + V PK + PK
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 950 AEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFG 1009
P + + V K GA +L + + + P P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYK----GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 1010 VSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQA--DQVDVKLP 1067
P S P + L D PAS K+ A Q LP
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLK-----------DSPTSPASVTCKMGATVPQASKGLP 1673
Query: 1068 EGHLPEG------AGLKGHLPKVEMPSFKMPKV----ALKGPQVDVKGPKLDLKSPKAEV 1117
P A P + P+ K P+ A P K K P + V
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 1118 T-APDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGAS 1176
AP + V S + + L S A +TA +PK + S A+
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA 1793
Query: 1177 APGKSIEASVDVSAPKVEADV-SLPSMQGDLKTT-DLSIQPPSADLEVHAGQVDVKLLEG 1234
S VS P + V +LP Q L ++ L ++ PS L A + ++ L
Sbjct: 1794 -------PSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL-APADEDELLPLIP 1845
Query: 1235 HVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSV 1294
P G V MP+ K + + P + + K +K T + S+P +
Sbjct: 1846 PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAK----QPVTKNNKGSGTESDSDESVPEL 1901
Query: 1295 EVDMQAPGAKLDGAQLDGDLSLADKDVT-AKDSK 1327
E + + A AQL + ++ V+ AK S+
Sbjct: 1902 E-EQDSTQATTQQAQLAAAAEIDEEPVSKAKQSR 1934
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 46.2 bits (108), Expect = 0.001
Identities = 54/242 (22%), Positives = 92/242 (38%), Gaps = 21/242 (8%)
Query: 211 PQGKEKEDTDVADGCRETPTKTLEG--DGDQERLISKPRVGRGRQSQRERLSWPKFQSIK 268
PQ + T G +P+ +G D ++E + RG ++++ + P+ +
Sbjct: 163 PQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRK---PQQPQCR 219
Query: 269 SKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDTEAQLTVERQEQKAGPGSQRRRKFLNLRF 328
G G +R SS + + + A D + A + + +K P +RR
Sbjct: 220 PAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQ 279
Query: 329 RTGSGQGPSSTGQPGRGFQSGVGRAGVLEELG--------------PWGDSLEETGAATG 374
R GSG PS+ Q + + A G P G + + G+
Sbjct: 280 RRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCS 339
Query: 375 SRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVA 434
S ++ QDRE A + P+PT G R + PQ+ R A G+ + +A
Sbjct: 340 SSANQQGAQDRE-EEAAAAPVPTSSGH-RTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQ 397
Query: 435 QR 436
QR
Sbjct: 398 QR 399
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 45.8 bits (107), Expect = 0.001
Identities = 86/357 (24%), Positives = 133/357 (37%), Gaps = 65/357 (18%)
Query: 250 RGRQSQRERLSWPKFQSI-----KSKRG---------------PGPQRSHSSSEAYEPRD 289
RGR ++R++ PK +++ +++ G P P R+ + A +
Sbjct: 29 RGRDQTKKRMAKPKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEAS 88
Query: 290 AHD------VSPTSTDTEAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPG 343
A D V+P ++ EAQ +G GSQ + G+G GP + G
Sbjct: 89 ALDTVGAEAVAPAASSAEAQ---------SGAGSQAQE-------ADGAGVGPKAESVVG 132
Query: 344 RGFQSGVG-RAGVLEELGPWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDP 402
S + GV E LG ++ GA + AE R +P ++ +PTE P
Sbjct: 133 AAMASAIAPPPGVTEALGA-AEAPAMAGAPKVAEAPREAETSRAAVPPGTV-VPTEAAAP 190
Query: 403 RLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGI 462
EG AA G A T A+ A PT + G E + G
Sbjct: 191 T----EVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGT--SGS 244
Query: 463 ARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQR--GKRQDAS 520
R ++ T + P H PK +T P+ + T R GK +
Sbjct: 245 PRTAVVPGTSAAKKATP-----GAHTGAIPKATSATGAVPKGGGKGVTRSRNGGKGKGKK 299
Query: 521 SKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTE 577
SK ++ +E+ G G+ PG A A + G+ L +EE + G DTE
Sbjct: 300 SK----VEVDEL-GMGFRPGDGAAAAAAASAN--GGQAFLAEVPDSEEGESGWTDTE 349
>gi|29540562 ALEX2 protein [Homo sapiens]
Length = 632
Score = 45.8 bits (107), Expect = 0.001
Identities = 86/357 (24%), Positives = 133/357 (37%), Gaps = 65/357 (18%)
Query: 250 RGRQSQRERLSWPKFQSI-----KSKRG---------------PGPQRSHSSSEAYEPRD 289
RGR ++R++ PK +++ +++ G P P R+ + A +
Sbjct: 29 RGRDQTKKRMAKPKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEAS 88
Query: 290 AHD------VSPTSTDTEAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPG 343
A D V+P ++ EAQ +G GSQ + G+G GP + G
Sbjct: 89 ALDTVGAEAVAPAASSAEAQ---------SGAGSQAQE-------ADGAGVGPKAESVVG 132
Query: 344 RGFQSGVG-RAGVLEELGPWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDP 402
S + GV E LG ++ GA + AE R +P ++ +PTE P
Sbjct: 133 AAMASAIAPPPGVTEALGA-AEAPAMAGAPKVAEAPREAETSRAAVPPGTV-VPTEAAAP 190
Query: 403 RLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGI 462
EG AA G A T A+ A PT + G E + G
Sbjct: 191 T----EVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGT--SGS 244
Query: 463 ARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQR--GKRQDAS 520
R ++ T + P H PK +T P+ + T R GK +
Sbjct: 245 PRTAVVPGTSAAKKATP-----GAHTGAIPKATSATGAVPKGGGKGVTRSRNGGKGKGKK 299
Query: 521 SKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTE 577
SK ++ +E+ G G+ PG A A + G+ L +EE + G DTE
Sbjct: 300 SK----VEVDEL-GMGFRPGDGAAAAAAASAN--GGQAFLAEVPDSEEGESGWTDTE 349
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.1 bits (105), Expect = 0.002
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 17/201 (8%)
Query: 499 EKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQG------- 551
E+E RE+RL + +R ++ L+ E+ E + RE E +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 552 -DEGDGEEGLQRTRITEEQDKGREDTEG-QIRMPKFKIPSLGWSPSKHTKTGREKATEDT 609
E ++ L+R +Q RE E + R+ + ++ L + + RE+ E+
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 610 EQG------REGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQIL 663
Q +E R +Q R E+ LK +E+ + + K + H+E+R ++E
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE--HEEERREQELAE 687
Query: 664 TEKEVATKDSKFKMPKFKMPL 684
E+E A + K ++PK++ L
Sbjct: 688 EEQEQARERIKSRIPKWQWQL 708
Score = 44.3 bits (103), Expect = 0.004
Identities = 92/487 (18%), Positives = 182/487 (37%), Gaps = 43/487 (8%)
Query: 197 PQDEEWASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQR 256
P+D + Q Q +++++ ++A+G ++ QERL + R R + R
Sbjct: 124 PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEK--------QERLEQRDRQRRDEELWR 175
Query: 257 ERLSWPKFQSIKSKRGPGPQ----RSHSSSEAYEP-----RDAHDVSPTSTDTEAQLTVE 307
+R W Q + +R Q + H + E + R+ ++ + + Q E
Sbjct: 176 QRQEW---QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232
Query: 308 RQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDSLE 367
RQ++ ++ + R + Q R Q + LE + E
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 368 ETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQ 427
E RRE++ + +E + E + R Q+ R +L + E +
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERR-----EQQEERREQQLRREQEERR 347
Query: 428 AQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVH 487
Q+ Q + R + + RE E E + +L Q+ + R
Sbjct: 348 EQQLRREQEEERREQQ--LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 488 DLKTPKFAFSTEKEPERERRLSTPQRGKRQDAS---SKAGTGLKGEEVEGAGWMPGREPT 544
L+ + E++ RE++L Q +R + + LK E+ E W+ E T
Sbjct: 406 QLRREQ-QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 545 THAEA----QGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKT 600
E Q + D EE + + E+++ RE E + + + + + +
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE--------QEERRE 516
Query: 601 GREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKE 660
R K E+ E+ ++ + RREQ E L +E+ + + Q + E+ +++
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 661 QILTEKE 667
Q+L +E
Sbjct: 577 QLLKREE 583
Score = 42.7 bits (99), Expect = 0.010
Identities = 62/310 (20%), Positives = 124/310 (40%), Gaps = 22/310 (7%)
Query: 377 REERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQR 436
++ R E+D+ + L E G R + QE L E Q+++ ++
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG-------EEQSEKQERLEQ 163
Query: 437 KPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAF 496
+ R + + R+ + E + E L+ T+ P E ++R +L +
Sbjct: 164 RDRQRRDEELWRQRQ-EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 497 STEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGD- 555
EK+ +R R + + + K T L+ EE + + EP E Q +E
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK----LQEEEPQRQRELQEEEEQL 278
Query: 556 ---GEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQG 612
+ L+R R EEQ + R E Q+R + + + + RE+ E EQ
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 613 ------REGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEK 666
E ++ E+RR ++ +++E+ + Q + E++L++EQ L +
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 667 EVATKDSKFK 676
+ ++ + +
Sbjct: 399 QQLRREQQLR 408
Score = 40.4 bits (93), Expect = 0.052
Identities = 71/297 (23%), Positives = 117/297 (39%), Gaps = 19/297 (6%)
Query: 376 RREERAEQDREVMPAQSMPLPTELGDPRLCEGTP----QEGGLRAARLHGKTLEGQAQET 431
R+++ EQ R+ +E G RL P +E LRA + +E
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 432 AVAQRK-PRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLK 490
QR+ R + + E E LQ E R E G Q E R +
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRE----RAQQLQEEEDGLQ-EDQERRRSQEQRR 870
Query: 491 TPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQ 550
K+ + E+E +R RR + + Q+ K L+ EE E + E Q
Sbjct: 871 DQKWRWQLEEERKR-RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 551 GDEGDGEEGLQRTRITEEQDKGR-EDTEGQIRMPKFKIPS-----LGWSPSKHTKTGREK 604
E + + + + EE++K R ++ E Q R K K+ LG P K + REK
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDK-KLQQKEEQLLGEEPEKRRRQEREK 988
Query: 605 ATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQ 661
+ E+ ++ E + RE+RR +E + D + + QL+ +E+ ++ Q
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE-QLLREEREKRRLQ 1044
Score = 33.5 bits (75), Expect = 6.3
Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
Query: 548 EAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATE 607
EA+ + +E Q R E+ + R++T+ + R + + P + + R+ E
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 608 DTEQGREGEATATADRR--EQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTE 665
+ +G ++R Q R + LK+++ +++ D K ++EQ L+
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 666 KEVATKDSKFK 676
+E +D KF+
Sbjct: 1426 QE---RDRKFR 1433
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 45.1 bits (105), Expect = 0.002
Identities = 72/289 (24%), Positives = 103/289 (35%), Gaps = 51/289 (17%)
Query: 4755 PSMQMPKVGFAGFPSSRLDLTGPHFESSILS----PCEDVTLTKYQVTVPRAALAP--EL 4808
PSM + + G AG P L L P F + + P + + LT V+ P + P
Sbjct: 929 PSMSV-RGGGAGQP---LPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPA 984
Query: 4809 ALEIPSGSQADIPLPKTECSTDLQPPEG----VPTSQAESHSGPLNSMIPVSLGQVSFPK 4864
L P+ + LP + T +Q G + TS A S +G + S P S + F
Sbjct: 985 TLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTS 1044
Query: 4865 FYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEE 4924
F P ++ + L L+PG+ P+PS QLP P GP
Sbjct: 1045 LGPSGPAFVQPLLSAGQAPL-----------LAPGQVGVSPVPSPQLP-PACAAPGGP-- 1090
Query: 4925 LVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDS 4984
+ T+ + AP+ A PL P PS ++ T P
Sbjct: 1091 ----VITAFYSGSPAPTSSA-------PLAQPSQAPPSLVYTVATSTTPPA--------- 1130
Query: 4985 KLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKA 5033
+ +L K AP +A P G T PK P KA
Sbjct: 1131 --ATILPKGPPAPATATPAPTSPFPSATAGSMTY-SLVAPKAQRPSPKA 1176
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 44.7 bits (104), Expect = 0.003
Identities = 73/305 (23%), Positives = 124/305 (40%), Gaps = 24/305 (7%)
Query: 1073 EGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVD 1132
EG GLK + + K + +KG ++ +L L K + A D + + V+
Sbjct: 805 EGLGLKLEDRETVIKELKK-SLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 863
Query: 1133 VEAPGAKLDSARLEGELSL----ADKD-VTAKDSRFKM---PKFKMPSFGASAPGKS--- 1181
+E A L E E ++ AD D + A+ + K + K G P S
Sbjct: 864 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIA 923
Query: 1182 -IEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGA 1240
+ + + A +A S+P G +K + L +Q SA + +H Q+ E + +GA
Sbjct: 924 TLVSGIAGGAIPGQAPGSVPG-PGLVKDSPLLLQQISA-MRLHISQLQH---ENSILKGA 978
Query: 1241 GFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQA 1300
K L +P L + K+ +GP E+ L K + T ++++ V++ +
Sbjct: 979 QMKASL--ASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTS 1036
Query: 1301 PGAKLDGAQLDGDL----SLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAP 1356
P AK AQL + SL+D KD K + P V + +S L A
Sbjct: 1037 PAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAK 1096
Query: 1357 KVEAD 1361
+ + D
Sbjct: 1097 EEQQD 1101
Score = 38.9 bits (89), Expect = 0.15
Identities = 72/330 (21%), Positives = 136/330 (41%), Gaps = 31/330 (9%)
Query: 3689 QPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKL 3748
+PP +L+ A + ++ EG GLK + + LK + +KG ++ +L
Sbjct: 786 KPPPVELRAAALRAEIT-----DAEGLGLKLEDRETVIKELKK-SLKIKGEELSEANVRL 839
Query: 3749 DLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSL----ADKD-VTAKDSKF 3803
L K + A D + + V+ ++ +A L + E + ++ AD D + A+ ++
Sbjct: 840 SLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAEL 899
Query: 3804 KM---PKFKMPSFGVSAPGKS----IEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPH 3856
K + K G+ P S + + + A +A S+P G +K + L +Q
Sbjct: 900 KQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPG-PGLVKDSPLLLQQI 958
Query: 3857 SA-DLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDL 3915
SA L + Q + +L+G A +K L +P + K+ +GP ++ L
Sbjct: 959 SAMRLHISQLQHENSILKG-----AQMKASL--ASLPPLHVAKLSHEGPGSELPAGALYR 1011
Query: 3916 KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDL----SLADKDMTAKDSKFKMP 3971
K ++ T + V++ +P AK A+L + SL+D KD K
Sbjct: 1012 KTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKET 1071
Query: 3972 KFKMPSFGVSAPGKSMEASVDVTAPKVEAD 4001
+ P V + +S + A + + D
Sbjct: 1072 VSQRPGATVPTDFATFPSSAFLRAKEEQQD 1101
Score = 35.0 bits (79), Expect = 2.2
Identities = 73/332 (21%), Positives = 127/332 (38%), Gaps = 35/332 (10%)
Query: 1214 QPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKL 1273
+PP +L A + ++ EG G K + + LK + +KG ++ +L
Sbjct: 786 KPPPVELRAAALRAEIT-----DAEGLGLKLEDRETVIKELKK-SLKIKGEELSEANVRL 839
Query: 1274 DLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKL-----------DGAQLDGDLSLADKDVT 1322
L K + A + + V+ ++ A L D Q D D A+K
Sbjct: 840 SLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK--- 896
Query: 1323 AKDSKFKMPKFKMPSFGVSAPGKS----IEASVDLSAPKVEADMSLPSMQGDLKTTDLSI 1378
A+ + + K G+ P S + + + A +A S+P G +K + L +
Sbjct: 897 AELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPG-PGLVKDSPLLL 955
Query: 1379 QPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKL 1438
Q S + L QL E + +GA +K L L P V K+ +GP ++ L
Sbjct: 956 QQISA-MRLHISQLQ---HENSILKGAQMKASLASL--PPLHVAKLSHEGPGSELPAGAL 1009
Query: 1439 DLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDM----SLADKDLTTKDSKFK 1494
K ++ T + V++ +P AK +L E + SL+D KD K
Sbjct: 1010 YRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLK 1069
Query: 1495 MPKFKMPSFGVSAPGKSIEASVDVSAPKVEAD 1526
+ P V + +S + A + + D
Sbjct: 1070 ETVSQRPGATVPTDFATFPSSAFLRAKEEQQD 1101
Score = 34.3 bits (77), Expect = 3.7
Identities = 100/446 (22%), Positives = 182/446 (40%), Gaps = 47/446 (10%)
Query: 2908 KVDLKGPQIDVKG-PKLDLKGPKAEVTAPDVEVSLP---SVEVDVEAPRAKLDG--ARLE 2961
K+ + P D G P GP+ T D L +V +V A A+L A E
Sbjct: 666 KIRRRMPGTDAPGIPAALAFGPQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENE 725
Query: 2962 GDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDL 3021
G L A +++ K S+ + PS S+P + + S ++ + +++ +G+
Sbjct: 726 GLLVAALEELAFKASE---QIYGTPS---SSPYECLRQSCNILISTMN-KLATAMQEGEY 778
Query: 3022 KTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQI 3081
+PP +L A + ++ EG GLK + + K + KG ++
Sbjct: 779 DAERPPSKPPPVELRAAALRAEIT-----DAEGLGLKLEDRETVIKELKK-SLKIKGEEL 832
Query: 3082 DVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSL----ADKD-V 3136
+L L K D A D + ++ +E A L E + ++ AD D +
Sbjct: 833 SEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 892
Query: 3137 TAKDSKFKM---PKFKMPSFGVSAPGKS-IEVLVDVSAPKV---EADLSLPSMQGDLKNT 3189
A+ ++ K + K G+ P S I LV A +A S+P G +K++
Sbjct: 893 EAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPG-PGLVKDS 951
Query: 3190 DISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIK 3249
+ ++ SA + + Q+ E +L+GA +K L L P + K+ +GP ++
Sbjct: 952 PLLLQQISA-MRLHISQLQ---HENSILKGAQMKASLASL--PPLHVAKLSHEGPGSELP 1005
Query: 3250 GPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDL----SLAD-----KD 3300
L K ++ T + +++ +P AK A+L + SL+D KD
Sbjct: 1006 AGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKD 1065
Query: 3301 VTAKDSKFKMPKFKMPSYRASAPGKS 3326
K++ + P +P+ A+ P +
Sbjct: 1066 EVLKETVSQRPGATVPTDFATFPSSA 1091
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 242,913,762
Number of Sequences: 37866
Number of extensions: 12906429
Number of successful extensions: 67524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 361
Number of HSP's that attempted gapping in prelim test: 31915
Number of HSP's gapped (non-prelim): 4614
length of query: 5795
length of database: 18,247,518
effective HSP length: 125
effective length of query: 5670
effective length of database: 13,514,268
effective search space: 76625899560
effective search space used: 76625899560
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.