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Search of human proteins with 156142188
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo
sapiens]
(915 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 1812 0.0
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 1741 0.0
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 1491 0.0
gi|56119110 family with sequence similarity 13, member A1 isofor... 642 0.0
gi|62865869 family with sequence similarity 13, member A1 isofor... 494 e-139
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 228 2e-59
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 228 2e-59
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 146 1e-34
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 104 3e-22
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 104 3e-22
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 104 3e-22
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 97 7e-20
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 95 3e-19
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 88 3e-17
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 88 3e-17
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 80 1e-14
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 80 1e-14
gi|188497642 ARHGAP15 [Homo sapiens] 79 3e-14
gi|91208437 GEM interacting protein [Homo sapiens] 78 3e-14
gi|186910302 Rac GTPase activating protein 1 [Homo sapiens] 77 6e-14
gi|186910300 Rac GTPase activating protein 1 [Homo sapiens] 77 6e-14
gi|21361397 Rac GTPase activating protein 1 [Homo sapiens] 77 6e-14
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 77 1e-13
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 76 2e-13
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 75 2e-13
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 75 3e-13
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 75 3e-13
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 75 3e-13
gi|23510413 sorting nexin 26 [Homo sapiens] 75 4e-13
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 73 1e-12
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 1812 bits (4693), Expect = 0.0
Identities = 915/915 (100%), Positives = 915/915 (100%)
Query: 1 MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL 60
MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL
Sbjct: 1 MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL 60
Query: 61 FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ 120
FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ
Sbjct: 61 FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ 120
Query: 121 LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD 180
LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD
Sbjct: 121 LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD 180
Query: 181 VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE 240
VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE
Sbjct: 181 VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE 240
Query: 241 DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE 300
DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE
Sbjct: 241 DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE 300
Query: 301 RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS 360
RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS
Sbjct: 301 RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS 360
Query: 361 ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL 420
ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL
Sbjct: 361 ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL 420
Query: 421 FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE 480
FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE
Sbjct: 421 FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE 480
Query: 481 EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL 540
EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL
Sbjct: 481 EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL 540
Query: 541 DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI 600
DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI
Sbjct: 541 DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI 600
Query: 601 AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED 660
AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED
Sbjct: 601 AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED 660
Query: 661 EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYE 720
EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYE
Sbjct: 661 EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYE 720
Query: 721 SQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 780
SQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH
Sbjct: 721 SQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 780
Query: 781 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS 840
FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS
Sbjct: 781 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS 840
Query: 841 MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR 900
MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR
Sbjct: 841 MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR 900
Query: 901 LLEVLISKQDSSKSI 915
LLEVLISKQDSSKSI
Sbjct: 901 LLEVLISKQDSSKSI 915
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 1741 bits (4509), Expect = 0.0
Identities = 887/915 (96%), Positives = 887/915 (96%), Gaps = 28/915 (3%)
Query: 1 MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL 60
MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL
Sbjct: 1 MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL 60
Query: 61 FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ 120
FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ
Sbjct: 61 FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ 120
Query: 121 LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD 180
LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD
Sbjct: 121 LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD 180
Query: 181 VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE 240
VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE
Sbjct: 181 VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE 240
Query: 241 DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE 300
DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE
Sbjct: 241 DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE 300
Query: 301 RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS 360
RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS
Sbjct: 301 RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS 360
Query: 361 ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL 420
ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL
Sbjct: 361 ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL 420
Query: 421 FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE 480
FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE
Sbjct: 421 FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE 480
Query: 481 EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL 540
EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL
Sbjct: 481 EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL 540
Query: 541 DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI 600
DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI
Sbjct: 541 DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI 600
Query: 601 AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED 660
AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED
Sbjct: 601 AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED 660
Query: 661 EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYE 720
EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK
Sbjct: 661 EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK---------------------- 698
Query: 721 SQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 780
VTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH
Sbjct: 699 ------VTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 752
Query: 781 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS 840
FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS
Sbjct: 753 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS 812
Query: 841 MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR 900
MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR
Sbjct: 813 MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR 872
Query: 901 LLEVLISKQDSSKSI 915
LLEVLISKQDSSKSI
Sbjct: 873 LLEVLISKQDSSKSI 887
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 1491 bits (3861), Expect = 0.0
Identities = 769/819 (93%), Positives = 769/819 (93%), Gaps = 50/819 (6%)
Query: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178
MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
Query: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238
PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
Query: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298
EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
Query: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358
LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
Query: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418
ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
Query: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478
LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
Query: 479 WE----------------------EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516
WE EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
Query: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576
PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
Query: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636
QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
Query: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696
RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
Query: 697 IKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITP 756
IK VTKEERHIVKPLYDRYRLVKQMLTRASITP
Sbjct: 601 IK----------------------------VTKEERHIVKPLYDRYRLVKQMLTRASITP 632
Query: 757 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 816
VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS
Sbjct: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
Query: 817 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 876
ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN
Sbjct: 693 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 752
Query: 877 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915
AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI
Sbjct: 753 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 642 bits (1656), Expect = 0.0
Identities = 416/1021 (40%), Positives = 591/1021 (57%), Gaps = 124/1021 (12%)
Query: 1 MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL 60
M+K + L+ K+FG+ L EL++ G +N +P +V ++V+Y+ +HG L Q+GL
Sbjct: 21 MKKIVAVPLNEQKDFTYQKLFGVSLQELERQGLTENGIPAVVWNIVEYLTQHG-LTQEGL 79
Query: 61 FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ 120
F+VNGN + VE LR +++SG V+L K+ DV SA SLL+ FL+ELP+ +I +L +Q
Sbjct: 80 FRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQ 139
Query: 121 LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGP 179
L QD N+ + LR L+++LP +Y LLK+LC+FL VA HH + + ++LA VFGP
Sbjct: 140 LFQDGRNDVQES-SLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGP 198
Query: 180 DVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENE------------------EEDFSS 221
+ FH+ +E MKEQ++ ++IMA +LENY FE E +E +
Sbjct: 199 NCFHVPPGLEGMKEQDLCNKIMAKILENYNTLFEVEYTENDHLRCENLARLIIVKEVYYK 258
Query: 222 NDL------------------SSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDMPE 263
N L + I + +E S + + E + +P+ S
Sbjct: 259 NSLPILLTRGLERDMPKPPPKTKIPKSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRKAC 318
Query: 264 VVQLRMTENILESNSVTAT------------STHISPISILPASTDILERTIRAAVEQHL 311
+ + E + + V ++ S H+ +S + A+ ++LERTIR+AVEQHL
Sbjct: 319 LEDMNSAEGAISAKLVPSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHL 378
Query: 312 FDL-----QSSIDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID------- 351
FD+ QSS D + L S + E H +G N+ +
Sbjct: 379 FDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNH 438
Query: 352 IADDIINASESNR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVG 396
+ D I+N E + + SKP +ST L QD + E+ +T+S
Sbjct: 439 LDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHE 498
Query: 397 IL----LEPCSD--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPG 450
E SD +G+ +DG + F+S + KI + + ++++
Sbjct: 499 RTGPDDFEWMSDERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQR 545
Query: 451 GQSVGVQGEAACVSIPHLDLKNVSDGDKWEEPFPAFKSWQ-EDSESGEAQLSPQAGRMNH 509
Q G Q E+ +P DL + D WEEP PAF SWQ E+S+S EA LSPQAGR+
Sbjct: 546 NQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIR 605
Query: 510 HPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTP 569
L+ED P+LS R +GQS+++L D E S + SF R R SS S D+++ED TP
Sbjct: 606 QLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTP 665
Query: 570 YQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHK 626
QL +++Q KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K R+Q+K++K K
Sbjct: 666 AQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLK 725
Query: 627 NSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKE 686
S+ + P+ R RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EATLE I ++L+E
Sbjct: 726 ISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEATLESIQRKLQE 782
Query: 687 KRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVK 746
KR E PEDIK MTKD + EK +LQK+LLYYES HGRPVTK ER ++KPLYDRYRLVK
Sbjct: 783 KRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVK 842
Query: 747 QMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEE---EDGVNLSSELGDML 803
Q+L+RA+ P++GSPS+KRR +LQPIIEGETA FF+EIKEEE ED N+ + L
Sbjct: 843 QILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTL 902
Query: 804 KTAVQVQSSLENSESDV--------EENQEKLALDLRLSSSRAASMPELLEQLWKARAEK 855
KT + L+ E D ++ K + D LS+ AAS+PELLE L + R EK
Sbjct: 903 KTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEK 962
Query: 856 KKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS-SKS 914
K++RK LR+FE+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEVLISK+D+ SKS
Sbjct: 963 KRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKS 1022
Query: 915 I 915
+
Sbjct: 1023 M 1023
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 494 bits (1271), Expect = e-139
Identities = 314/710 (44%), Positives = 429/710 (60%), Gaps = 73/710 (10%)
Query: 263 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 317
E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS
Sbjct: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63
Query: 318 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 362
D + L S + E H +G N+ + + D I+N E
Sbjct: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123
Query: 363 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 403
+ + SKP +ST L QD + E+ +T+S E S
Sbjct: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183
Query: 404 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 461
D +G+ +DG + F+S + KI + + ++++ Q G Q E+
Sbjct: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230
Query: 462 CVSIPHLDLKNVSDGDKWEEPFPAFKSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVL 520
+P DL + D WEEP PAF SWQ E+S+S EA LSPQAGR+ L+ED P+L
Sbjct: 231 VSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPML 290
Query: 521 SHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ--- 577
S R +GQS+++L D E S + SF R R SS S D+++ED TP QL +++Q
Sbjct: 291 SPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLK 350
Query: 578 KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTR 637
KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K R+Q+K++K K S+ + P+ R
Sbjct: 351 KKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMR 410
Query: 638 PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDI 697
RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EATLE I ++L+EKR E PEDI
Sbjct: 411 QRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDI 467
Query: 698 KKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPV 757
K MTKD + EK +LQK+LLYYES HGRPVTK ER ++KPLYDRYRLVKQ+L+RA+ P+
Sbjct: 468 KDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPI 527
Query: 758 LGSPSTKRRGQMLQPIIEGETAHFFEEIKEEE---EDGVNLSSELGDMLKTAVQVQSSLE 814
+GSPS+KRR +LQPIIEGETA FF+EIKEEE ED N+ + LKT + L+
Sbjct: 528 IGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLD 587
Query: 815 NSESDV--------EENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 866
E D ++ K + D LS+ AAS+PELLE L + R EKK++RK LR+FE
Sbjct: 588 QFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFE 647
Query: 867 EAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS-SKSI 915
+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEVLISK+D+ SKS+
Sbjct: 648 DNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRDTDSKSM 697
>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
Length = 585
Score = 228 bits (582), Expect = 2e-59
Identities = 165/457 (36%), Positives = 241/457 (52%), Gaps = 75/457 (16%)
Query: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 190 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 248
Query: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 249 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 308
Query: 589 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NT 642
+E+ +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T
Sbjct: 309 QEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPT 368
Query: 643 LPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTK 702
+P+ G +P+ E S E T + L LKE+R + ED K
Sbjct: 369 VPRENG------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSK---- 412
Query: 703 DHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVL---- 758
VTK++++++KPLYDRYR++KQ+L+ S+ P +
Sbjct: 413 ------------------------VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEE 448
Query: 759 GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSES 818
S + +G QP + +H D + S+E V++ L + +
Sbjct: 449 DSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEPVRALLPDEKK 494
Query: 819 DVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQ 878
+V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE F++Q GR+ Q
Sbjct: 495 EVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQ 548
Query: 879 KEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915
KEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 549 KEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 585
>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
Length = 502
Score = 228 bits (582), Expect = 2e-59
Identities = 165/457 (36%), Positives = 241/457 (52%), Gaps = 75/457 (16%)
Query: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 107 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 165
Query: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 166 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 225
Query: 589 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NT 642
+E+ +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T
Sbjct: 226 QEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPT 285
Query: 643 LPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTK 702
+P+ G +P+ E S E T + L LKE+R + ED K
Sbjct: 286 VPRENG------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSK---- 329
Query: 703 DHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVL---- 758
VTK++++++KPLYDRYR++KQ+L+ S+ P +
Sbjct: 330 ------------------------VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEE 365
Query: 759 GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSES 818
S + +G QP + +H D + S+E V++ L + +
Sbjct: 366 DSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEPVRALLPDEKK 411
Query: 819 DVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQ 878
+V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE F++Q GR+ Q
Sbjct: 412 EVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQ 465
Query: 879 KEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915
KEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 466 KEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 502
>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
Length = 487
Score = 146 bits (368), Expect = 1e-34
Identities = 96/261 (36%), Positives = 148/261 (56%), Gaps = 35/261 (13%)
Query: 665 IQKEKKPSKEATLELILKRLKEKRIERCL------PEDIKKMTKDHLVEEKASLQKSLLY 718
+ E PS +T + ++ R RC P+ I ++TK H+ K ++K
Sbjct: 252 LDPESAPSPPSTQQFMMPRSSS----RCSCGDGKEPQTITQLTK-HIQSLKRKIRKFEEK 306
Query: 719 YESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPII 774
+E + VTK++++++KPLYDRYR++KQ+L+ S+ P + S + +G QP +
Sbjct: 307 FEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSL 365
Query: 775 EGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLS 834
+H D + S+E V++ L + + +V+ L +S
Sbjct: 366 ADPASHL------PVGDHLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMS 406
Query: 835 SSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKK 894
+ A+MP LL+ L + RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK
Sbjct: 407 NLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKH 466
Query: 895 IKAKLRLLEVLISKQDSSKSI 915
IKAKLRLLEVLISKQD +K+I
Sbjct: 467 IKAKLRLLEVLISKQDVAKTI 487
Score = 84.7 bits (208), Expect = 4e-16
Identities = 87/306 (28%), Positives = 133/306 (43%), Gaps = 53/306 (17%)
Query: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 190 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 248
Query: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 249 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 308
Query: 589 RERNSKPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPR 639
+E+ + + D + +++K + L I++ + + D G P
Sbjct: 309 QEKKYRVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADP 368
Query: 640 SNTLPKSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEK 687
++ LP DH NE EP ++ EKK K EAT+ ++L L+E
Sbjct: 369 ASHLPVG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRET 423
Query: 688 RIERCLPEDIKKMTKDHLVEEKASLQKSLLYYESQH----GRPVTKEERHIVKPLYDRYR 743
R +K L+K+L +E Q GR KE+R + Y Y+
Sbjct: 424 R------------------ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 465
Query: 744 LVKQML 749
+K L
Sbjct: 466 HIKAKL 471
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 104 bits (260), Expect = 3e-22
Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)
Query: 20 IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77
IFG L++ + + + P +V VD+I + G L+++GLF++ G A V+ L+ +
Sbjct: 37 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 95
Query: 78 DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136
D GE+ DV + SLL+ +L+ELPEPVIP + + + ++ + E+E G ++L
Sbjct: 96 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 155
Query: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191
++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ + VED M
Sbjct: 156 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 213
Query: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217
+ +V ++M+ ++ + F + E
Sbjct: 214 EGTVVVQQLMSVMISKHDCLFPKDAE 239
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 104 bits (260), Expect = 3e-22
Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)
Query: 20 IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77
IFG L++ + + + P +V VD+I + G L+++GLF++ G A V+ L+ +
Sbjct: 39 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 97
Query: 78 DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136
D GE+ DV + SLL+ +L+ELPEPVIP + + + ++ + E+E G ++L
Sbjct: 98 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 157
Query: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191
++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ + VED M
Sbjct: 158 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 215
Query: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217
+ +V ++M+ ++ + F + E
Sbjct: 216 EGTVVVQQLMSVMISKHDCLFPKDAE 241
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 104 bits (260), Expect = 3e-22
Identities = 68/206 (33%), Positives = 117/206 (56%), Gaps = 11/206 (5%)
Query: 20 IFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRY 77
IFG L++ + + + P +V VD+I + G L+++GLF++ G A V+ L+ +
Sbjct: 132 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRG-LKEEGLFRLPGQANLVKELQDAF 190
Query: 78 DSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFG-RKLR 136
D GE+ DV + SLL+ +L+ELPEPVIP + + + ++ + E+E G ++L
Sbjct: 191 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 250
Query: 137 FLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFHIYTDVED----M 191
++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ + VED M
Sbjct: 251 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI--LRPKVEDPLTIM 308
Query: 192 KEQEIVSRIMAGLLENYYEFFENEEE 217
+ +V ++M+ ++ + F + E
Sbjct: 309 EGTVVVQQLMSVMISKHDCLFPKDAE 334
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 97.1 bits (240), Expect = 7e-20
Identities = 69/236 (29%), Positives = 117/236 (49%), Gaps = 7/236 (2%)
Query: 16 LANKIFGIPLDEL--QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWL 73
L IFG L+E + + P +V VD+I E G L ++GLF++ G A V L
Sbjct: 148 LGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERG-LTEEGLFRMPGQANLVRDL 206
Query: 74 RQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGR 133
+ +D GE+ DV + SLL+ +L+ELPEPV+P + + + +Q ++ G
Sbjct: 207 QDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGT 266
Query: 134 -KLRFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVF--HIYTDVE 189
+L + LP NY+LL+++C+FL V ++ + S +LA VFGP++ + V
Sbjct: 267 LELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVT 326
Query: 190 DMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLE 245
M+ +V +M L+ + + F + ++ + V SEE D + E
Sbjct: 327 IMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGE 382
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 95.1 bits (235), Expect = 3e-19
Identities = 61/204 (29%), Positives = 107/204 (52%), Gaps = 8/204 (3%)
Query: 16 LANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQ 75
L N+ FG+ L LQ+ +P ++R V Y++ H L +G+F+ + N + V ++Q
Sbjct: 237 LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHA-LTTEGIFRRSANTQVVREVQQ 295
Query: 76 RYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKL 135
+Y+ G VD + ++ +L+ FL+ELPEP++ L+ H++ + N DE R
Sbjct: 296 KYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVV----GFLNIDESQRVP 351
Query: 136 RFL--LQQLPPVNYSLLKFLCRFLANVASHHEEIWSAN-SLAAVFGPDVFHIYTDVEDMK 192
L LQ LP NY +L+FL FL +++H ++ N +LA VFGP++ +K
Sbjct: 352 ATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLK 411
Query: 193 EQEIVSRIMAGLLENYYEFFENEE 216
++ LL++ E F + +
Sbjct: 412 AINPINTFTKFLLDHQGELFPSPD 435
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 88.2 bits (217), Expect = 3e-17
Identities = 66/207 (31%), Positives = 111/207 (53%), Gaps = 13/207 (6%)
Query: 20 IFGIPLDEL---QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76
+FG LDE +Q P + VP +V ++I EHG E+ G+F++ G V+ LR
Sbjct: 156 VFGQRLDETVAYEQKFGP-HLVPILVEKCAEFILEHGRNEE-GIFRLPGQDNLVKQLRDA 213
Query: 77 YDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYN-NEDEFGRKL 135
+D+GE ++ DV + SLL+ +L++LPEPV+P S + + Q N +E + ++L
Sbjct: 214 FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 273
Query: 136 RFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVFHIYTDVED---- 190
L LP NYSLL ++CRFL + + S ++LA V G ++ I + VED
Sbjct: 274 MKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNL--IRSKVEDPAVI 331
Query: 191 MKEQEIVSRIMAGLLENYYEFFENEEE 217
M+ + R+M ++ ++ F ++
Sbjct: 332 MRGTPQIQRVMTMMIRDHEVLFPKSKD 358
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 88.2 bits (217), Expect = 3e-17
Identities = 66/207 (31%), Positives = 111/207 (53%), Gaps = 13/207 (6%)
Query: 20 IFGIPLDEL---QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76
+FG LDE +Q P + VP +V ++I EHG E+ G+F++ G V+ LR
Sbjct: 149 VFGQRLDETVAYEQKFGP-HLVPILVEKCAEFILEHGRNEE-GIFRLPGQDNLVKQLRDA 206
Query: 77 YDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYN-NEDEFGRKL 135
+D+GE ++ DV + SLL+ +L++LPEPV+P S + + Q N +E + ++L
Sbjct: 207 FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 266
Query: 136 RFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVFHIYTDVED---- 190
L LP NYSLL ++CRFL + + S ++LA V G ++ I + VED
Sbjct: 267 MKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNL--IRSKVEDPAVI 324
Query: 191 MKEQEIVSRIMAGLLENYYEFFENEEE 217
M+ + R+M ++ ++ F ++
Sbjct: 325 MRGTPQIQRVMTMMIRDHEVLFPKSKD 351
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 79.7 bits (195), Expect = 1e-14
Identities = 53/199 (26%), Positives = 107/199 (53%), Gaps = 8/199 (4%)
Query: 21 FGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSG 80
FG+PL +L P +P V V++IE+ G L +GL++V+GN + +++++D
Sbjct: 1260 FGMPLQDLVTAEKP---IPLFVEKCVEFIEDTG-LCTEGLYRVSGNKTDQDNIQKQFDQD 1315
Query: 81 EEVDLVK-EADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLL 139
++LV E V + L+ F +LP+P+IP SLH L++ ++ ++ E L+ ++
Sbjct: 1316 HNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-IPDKTERLHALKEIV 1374
Query: 140 QQLPPVNYSLLKFLCRFLANVASHHE-EIWSANSLAAVFGPDVFH-IYTDVEDMKEQEIV 197
++ PVNY + +++ L V+ H+ + +A++L+ F P + + + E + +I
Sbjct: 1375 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIH 1434
Query: 198 SRIMAGLLENYYEFFENEE 216
++ ++ FF N E
Sbjct: 1435 QSVVETFIQQCQFFFYNGE 1453
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 79.7 bits (195), Expect = 1e-14
Identities = 53/199 (26%), Positives = 107/199 (53%), Gaps = 8/199 (4%)
Query: 21 FGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSG 80
FG+PL +L P +P V V++IE+ G L +GL++V+GN + +++++D
Sbjct: 1259 FGMPLQDLVTAEKP---IPLFVEKCVEFIEDTG-LCTEGLYRVSGNKTDQDNIQKQFDQD 1314
Query: 81 EEVDLVK-EADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLL 139
++LV E V + L+ F +LP+P+IP SLH L++ ++ ++ E L+ ++
Sbjct: 1315 HNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-IPDKTERLHALKEIV 1373
Query: 140 QQLPPVNYSLLKFLCRFLANVASHHE-EIWSANSLAAVFGPDVFH-IYTDVEDMKEQEIV 197
++ PVNY + +++ L V+ H+ + +A++L+ F P + + + E + +I
Sbjct: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIH 1433
Query: 198 SRIMAGLLENYYEFFENEE 216
++ ++ FF N E
Sbjct: 1434 QSVVETFIQQCQFFFYNGE 1452
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 78.6 bits (192), Expect = 3e-14
Identities = 59/217 (27%), Positives = 108/217 (49%), Gaps = 10/217 (4%)
Query: 7 PSLSNCNS--VLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVN 64
PSL ++ ++IFG L ++ + ++ VP+ V+ ++ +E+ G L+ G+++V+
Sbjct: 263 PSLKTLQEKGLIKDQIFGSHLHKVCE--RENSTVPWFVKQCIEAVEKRG-LDVDGIYRVS 319
Query: 65 GNAETVEWLRQRYDSGEEVDLVKEA--DVPSAISLLRFFLQELPEPVIPGSLHIHLMQLS 122
GN T++ LR + E+++L D+ L+ F +ELPEP+ P S ++
Sbjct: 320 GNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAI 379
Query: 123 QDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLAN-VASHHEEIWSANSLAAVFGPDV 181
+ +N ++ L+Q+LPP N +K L L VA + + S SL VFGP +
Sbjct: 380 KKQDNNTRI-EAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTL 438
Query: 182 FHIYTDVEDMKEQEIVSRIMAGL-LENYYEFFENEEE 217
+ +M + +A L L Y + F +EE+
Sbjct: 439 LRAENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED 475
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 78.2 bits (191), Expect = 3e-14
Identities = 61/172 (35%), Positives = 88/172 (51%), Gaps = 15/172 (8%)
Query: 20 IFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDS 79
+FG+ D LQ EVPF+V IE H L+ QG+++V+G+ VE L Q +++
Sbjct: 548 LFGV--DFLQLPRDFPEEVPFVVTKCTAEIE-HRALDVQGIYRVSGSRVRVERLCQAFEN 604
Query: 80 GEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNE----------- 128
G + + S+L+ FLQEL EPVIP L+ + L++ + +
Sbjct: 605 GRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPS 664
Query: 129 DEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGP 179
E R L+ LL QLP NY+ L+ L L VA+ E SAN+L VFGP
Sbjct: 665 PEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGP 716
>gi|186910302 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 77.4 bits (189), Expect = 6e-14
Identities = 73/263 (27%), Positives = 131/263 (49%), Gaps = 19/263 (7%)
Query: 38 VPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAI-S 96
+P IV H V+ IE+ G L + GL++++G TV+ L++++ + V L+ + D AI S
Sbjct: 362 IPSIVVHCVNEIEQRG-LTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+ L EP++ L+ M+ ++ +ED + + +LP N L FL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAE-ITDEDNSIAAMYQAVGELPQANRDTLAFLMIH 479
Query: 157 LANVASHHEEIWSANSLAAVFGPDVF-------HIYTDVEDMKEQ-EIVSRIMAGLLENY 208
L VA +LA VFGP + T ++D+K Q ++V R+++ LE +
Sbjct: 480 LQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYW 539
Query: 209 YEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEEL--PEEGAEK---SNDMPE 263
+F E+E+ D + E N S + D K+ + + PE K S+ + +
Sbjct: 540 SQFMMVEQENI---DPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQ 596
Query: 264 VVQLRMTENILESNSVTATSTHI 286
V+ +T+N S + ++T++
Sbjct: 597 RVRSTLTKNTPRFGSKSKSATNL 619
>gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 77.4 bits (189), Expect = 6e-14
Identities = 73/263 (27%), Positives = 131/263 (49%), Gaps = 19/263 (7%)
Query: 38 VPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAI-S 96
+P IV H V+ IE+ G L + GL++++G TV+ L++++ + V L+ + D AI S
Sbjct: 362 IPSIVVHCVNEIEQRG-LTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+ L EP++ L+ M+ ++ +ED + + +LP N L FL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAE-ITDEDNSIAAMYQAVGELPQANRDTLAFLMIH 479
Query: 157 LANVASHHEEIWSANSLAAVFGPDVF-------HIYTDVEDMKEQ-EIVSRIMAGLLENY 208
L VA +LA VFGP + T ++D+K Q ++V R+++ LE +
Sbjct: 480 LQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYW 539
Query: 209 YEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEEL--PEEGAEK---SNDMPE 263
+F E+E+ D + E N S + D K+ + + PE K S+ + +
Sbjct: 540 SQFMMVEQENI---DPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQ 596
Query: 264 VVQLRMTENILESNSVTATSTHI 286
V+ +T+N S + ++T++
Sbjct: 597 RVRSTLTKNTPRFGSKSKSATNL 619
>gi|21361397 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 77.4 bits (189), Expect = 6e-14
Identities = 73/263 (27%), Positives = 131/263 (49%), Gaps = 19/263 (7%)
Query: 38 VPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAI-S 96
+P IV H V+ IE+ G L + GL++++G TV+ L++++ + V L+ + D AI S
Sbjct: 362 IPSIVVHCVNEIEQRG-LTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+ L EP++ L+ M+ ++ +ED + + +LP N L FL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAE-ITDEDNSIAAMYQAVGELPQANRDTLAFLMIH 479
Query: 157 LANVASHHEEIWSANSLAAVFGPDVF-------HIYTDVEDMKEQ-EIVSRIMAGLLENY 208
L VA +LA VFGP + T ++D+K Q ++V R+++ LE +
Sbjct: 480 LQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYW 539
Query: 209 YEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEEL--PEEGAEK---SNDMPE 263
+F E+E+ D + E N S + D K+ + + PE K S+ + +
Sbjct: 540 SQFMMVEQENI---DPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQ 596
Query: 264 VVQLRMTENILESNSVTATSTHI 286
V+ +T+N S + ++T++
Sbjct: 597 RVRSTLTKNTPRFGSKSKSATNL 619
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 76.6 bits (187), Expect = 1e-13
Identities = 78/291 (26%), Positives = 132/291 (45%), Gaps = 45/291 (15%)
Query: 34 PDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPS 93
PD VPFIV+ V IE L +G+++VNG VE L Q +++G+E+ + +A
Sbjct: 771 PDG-VPFIVKKCVCEIERRA-LRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHD 828
Query: 94 AISLLRFFLQELPEPVIPGSLHIHLMQLSQDY----------------NNEDE-----FG 132
++L+ +L++LPEP+I L+ L+ L++D +E E
Sbjct: 829 ISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALA 888
Query: 133 RKLRFLLQQLPPVNYSLLKFLCRFLANVAS-HHEEIWSANSLAAVFGPDVF-----HIYT 186
+LR LL+ LPP N + L++L R L + + + +L VFGP +
Sbjct: 889 GRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATV 948
Query: 187 DVEDMKEQEIVSRIMAGLLENYYEFFENEEE------DFSSNDLSSITEQVNELSEEEEE 240
+ + + +R++ L+ +Y FE E E D SSN + + QV L E
Sbjct: 949 SLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYL---EAG 1005
Query: 241 DEKLEHIEELPEEGAEK----SNDMPEVVQLRMTENILESNSVTATSTHIS 287
+ + ++E +G + SND L +L S+ +A H+S
Sbjct: 1006 EAVVYPLQEAAADGCRESRVVSNDSDS--DLEEASELLSSSEASALG-HLS 1053
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 75.9 bits (185), Expect = 2e-13
Identities = 65/271 (23%), Positives = 128/271 (47%), Gaps = 30/271 (11%)
Query: 17 ANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76
A FG L E + D VP++++ ++IE HG ++ G+++++G ++ LRQ
Sbjct: 15 AASAFGCDLTEYLESSGQD--VPYVLKSCAEFIETHGIVD--GIYRLSGVTSNIQRLRQE 70
Query: 77 YDSGEEVDLVKEA---DVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGR 133
+ S + DL +E D+ SL + + +ELP P++ L+ + E + R
Sbjct: 71 FGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130
Query: 134 KLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEI-WSANSLAAVFGPDVFHIYTDVE--- 189
++ ++Q+LPP +Y L++L R LA++AS + A +LA V+ P++ ++E
Sbjct: 131 -IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLR-SKEIEATG 188
Query: 190 --------DMKEQEIVSRIMAGLLENYYE-----FFENEEED--FSSNDLSSITEQVNEL 234
++ Q++V + ++ + EN+E S L +++ + +
Sbjct: 189 CNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIMKSLTLPALSLPMKLV 248
Query: 235 SEEEEEDEKLEHIEELPEEGAEKSNDMPEVV 265
S EE + L P + N +PE+V
Sbjct: 249 SLEEAQARSL--ATNHPARKERRENSLPEIV 277
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 75.5 bits (184), Expect = 2e-13
Identities = 45/176 (25%), Positives = 95/176 (53%), Gaps = 9/176 (5%)
Query: 7 PSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGN 66
P S + + FG+PL + P+ +P + ++YIE G L +G+++V+GN
Sbjct: 1233 PRPSITKATWESNYFGVPLTTVVT---PEKPIPIFIERCIEYIEATG-LSTEGIYRVSGN 1288
Query: 67 AETVEWLRQRYDSGEEVDLV-KEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDY 125
+E L++++D +DL K+ V + ++ F ELP+P++P ++ I L++ +
Sbjct: 1289 KSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVE-AHKI 1347
Query: 126 NNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEI--WSANSLAAVFGP 179
N+ ++ L+ +L++ P N+ + K++ L N SH+ ++ ++ +L+ F P
Sbjct: 1348 NDREQKLHALKEVLKKFPKENHEVFKYVISHL-NKVSHNNKVNLMTSENLSICFWP 1402
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 75.1 bits (183), Expect = 3e-13
Identities = 53/197 (26%), Positives = 98/197 (49%), Gaps = 24/197 (12%)
Query: 37 EVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAIS 96
+VP +V ++E+HG L+ G+F+V + + V LR+ +D G +V L +E V +
Sbjct: 206 QVPRLVDSCCQHLEKHG-LQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 264
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+++P+P++ L+ + + E++ G L+ L+ LPP N L L +F
Sbjct: 265 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLG-TLQLLIYLLPPCNCDTLHRLLQF 322
Query: 157 LANVASHHEEIWSAN------------SLAAVFGPDVFHIYTDVED---------MKEQE 195
L+ VA H ++ S + +LA +FGP++ H + +E
Sbjct: 323 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEEST 382
Query: 196 IVSRIMAGLLENYYEFF 212
+ ++ ++ENY F
Sbjct: 383 AIIAVVQKMIENYEALF 399
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 75.1 bits (183), Expect = 3e-13
Identities = 53/197 (26%), Positives = 98/197 (49%), Gaps = 24/197 (12%)
Query: 37 EVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAIS 96
+VP +V ++E+HG L+ G+F+V + + V LR+ +D G +V L +E V +
Sbjct: 409 QVPRLVDSCCQHLEKHG-LQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+++P+P++ L+ + + E++ G L+ L+ LPP N L L +F
Sbjct: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLG-TLQLLIYLLPPCNCDTLHRLLQF 525
Query: 157 LANVASHHEEIWSAN------------SLAAVFGPDVFHIYTDVED---------MKEQE 195
L+ VA H ++ S + +LA +FGP++ H + +E
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEEST 585
Query: 196 IVSRIMAGLLENYYEFF 212
+ ++ ++ENY F
Sbjct: 586 AIIAVVQKMIENYEALF 602
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 75.1 bits (183), Expect = 3e-13
Identities = 53/197 (26%), Positives = 98/197 (49%), Gaps = 24/197 (12%)
Query: 37 EVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAIS 96
+VP +V ++E+HG L+ G+F+V + + V LR+ +D G +V L +E V +
Sbjct: 409 QVPRLVDSCCQHLEKHG-LQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAA 467
Query: 97 LLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRF 156
LL+ FL+++P+P++ L+ + + E++ G L+ L+ LPP N L L +F
Sbjct: 468 LLKEFLRDMPDPLLTRELYTAFIN-TLLLEPEEQLG-TLQLLIYLLPPCNCDTLHRLLQF 525
Query: 157 LANVASHHEEIWSAN------------SLAAVFGPDVFHIYTDVED---------MKEQE 195
L+ VA H ++ S + +LA +FGP++ H + +E
Sbjct: 526 LSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEEST 585
Query: 196 IVSRIMAGLLENYYEFF 212
+ ++ ++ENY F
Sbjct: 586 AIIAVVQKMIENYEALF 602
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 74.7 bits (182), Expect = 4e-13
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 11/186 (5%)
Query: 1 MRKSSSPSLSNCNSVLANKIFGIPLDE-LQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQG 59
MR S +L ++FG L E L G +VP ++R ++IE HG ++ G
Sbjct: 293 MRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQ---DVPQVLRCCSEFIEAHGVVD--G 347
Query: 60 LFQVNGNAETVEWLRQRYDSGEEVDLVKEA---DVPSAISLLRFFLQELPEPVIPGSLHI 116
+++++G + ++ LR +DS +L A D+ S SL + + +ELP P++ L+
Sbjct: 348 IYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYG 407
Query: 117 HLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEI-WSANSLAA 175
+ + E+E ++ ++QQLPP +Y L++L R LA +A H A +LA
Sbjct: 408 KFSE-AMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAI 466
Query: 176 VFGPDV 181
V+ P++
Sbjct: 467 VWAPNL 472
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 11/169 (6%)
Query: 16 LANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQ 75
+ +++FG L L + + VP V+ + +E G L+ GL++++GN T++ LR
Sbjct: 322 IKDQVFGCALAALCE--RERSRVPRFVQQCIRAVEARG-LDIDGLYRISGNLATIQKLRY 378
Query: 76 RYDSGEEVDL--VKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGR 133
+ D E +DL + DV L+ F +ELPEP+ P S H Q +D+ R
Sbjct: 379 KVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFS---HFRQFIAAIKLQDQARR 435
Query: 134 K--LRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGP 179
+R L++ LP N+ L+ L + L V H E+ S S+A VFGP
Sbjct: 436 SRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGP 484
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,767,177
Number of Sequences: 37866
Number of extensions: 1769755
Number of successful extensions: 11923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 535
Number of HSP's that attempted gapping in prelim test: 8882
Number of HSP's gapped (non-prelim): 2751
length of query: 915
length of database: 18,247,518
effective HSP length: 111
effective length of query: 804
effective length of database: 14,044,392
effective search space: 11291691168
effective search space used: 11291691168
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.