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Search of human proteins with 154800493
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154800493 PRAME family member 22 [Homo sapiens]
(481 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154800493 PRAME family member 22 [Homo sapiens] 979 0.0
gi|194306638 PRAME family member 3 [Homo sapiens] 972 0.0
gi|153791443 PRAME family member 18 [Homo sapiens] 895 0.0
gi|194306635 PRAME family member 19 [Homo sapiens] 892 0.0
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 695 0.0
gi|194018546 PRAME family member 10 [Homo sapiens] 585 e-167
gi|157426839 PRAME family member 17 [Homo sapiens] 571 e-163
gi|113865933 PRAME family member 16 [Homo sapiens] 569 e-162
gi|12738831 PRAME family member 1 [Homo sapiens] 561 e-160
gi|66954681 PRAME family member 13 [Homo sapiens] 552 e-157
gi|12738834 PRAME family member 2 [Homo sapiens] 545 e-155
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 542 e-154
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 542 e-154
gi|153792140 PRAME family member 14 [Homo sapiens] 486 e-137
gi|124249372 PRAME family member 12 [Homo sapiens] 476 e-134
gi|153792112 PRAME family member 20 [Homo sapiens] 462 e-130
gi|153945800 PRAME family member 21 [Homo sapiens] 462 e-130
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 441 e-124
gi|59676587 PRAME family member 8 [Homo sapiens] 441 e-124
gi|59676593 PRAME family member 7 [Homo sapiens] 438 e-123
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 426 e-119
gi|148356236 PRAME family member 15 [Homo sapiens] 426 e-119
gi|61102721 PRAME family member 9 [Homo sapiens] 426 e-119
gi|61696142 PRAME family member 5 [Homo sapiens] 422 e-118
gi|58219004 PRAME family member 6 [Homo sapiens] 421 e-118
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 420 e-117
gi|59958373 PRAME family member 4 [Homo sapiens] 419 e-117
gi|226437621 PRAME family member 11 [Homo sapiens] 362 e-100
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 360 2e-99
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 360 2e-99
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 979 bits (2532), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240
HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240
Query: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL
Sbjct: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
Query: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD
Sbjct: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
Query: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES
Sbjct: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
Query: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP
Sbjct: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
Query: 481 A 481
A
Sbjct: 481 A 481
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 972 bits (2512), Expect = 0.0
Identities = 479/481 (99%), Positives = 479/481 (99%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLELRDVDENFWTIWSG
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSG 120
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240
HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEF RYLSQMRNLRKLF
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLF 240
Query: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL
Sbjct: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
Query: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD
Sbjct: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
Query: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES
Sbjct: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
Query: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP
Sbjct: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
Query: 481 A 481
A
Sbjct: 481 A 481
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 895 bits (2313), Expect = 0.0
Identities = 442/479 (92%), Positives = 456/479 (95%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I DSKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
+RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 892 bits (2304), Expect = 0.0
Identities = 441/479 (92%), Positives = 455/479 (94%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
+RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 695 bits (1793), Expect = 0.0
Identities = 360/469 (76%), Positives = 387/469 (82%), Gaps = 1/469 (0%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLELRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFS YLSQMRNLRKLFIS
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
DGCRYLLSSDSQEQ +A F++ L+L LQ LY+ V F GHLDQL+ CL++ L+ L +
Sbjct: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I DS++ ILPALS C L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
G + T ++AELM+ +R++R PKRI FG CP CG LE
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 585 bits (1508), Expect = e-167
Identities = 298/473 (63%), Positives = 359/473 (75%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMKT LE L V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+ YLSQM NLR+LF++
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
G L Q + + S L L Y QMLY++++ + HL+ L+R L++PL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 571 bits (1472), Expect = e-163
Identities = 294/473 (62%), Positives = 354/473 (74%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+ YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
G L Q+Q V + L L Y QMLY+R++ + HL+ L+RCL++PL T
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
+ +L D++CL +YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+RG V E+L P++AELM LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 569 bits (1467), Expect = e-162
Identities = 293/473 (61%), Positives = 353/473 (74%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+ YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
G L Q+Q V + L L Y QMLY+R++ + HL+ L+RCL++PL T
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
+ +L D++CL +YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+RG V E+L P++AELM LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 561 bits (1447), Expect = e-160
Identities = 293/473 (61%), Positives = 348/473 (73%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+K+VNY I R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Y ++ Q +LVA+FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I S+L ILPALS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
RV E+ TPL+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 552 bits (1422), Expect = e-157
Identities = 291/474 (61%), Positives = 346/474 (72%), Gaps = 2/474 (0%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 243 DGCRYLLSSDSQE-QLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
C + +S + E +LV +FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L
Sbjct: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
LTYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
I S+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL
Sbjct: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+ RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 545 bits (1405), Expect = e-155
Identities = 287/473 (60%), Positives = 340/473 (71%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F CLPL SLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+K+VNY I R L+ +Y +SI LEI N CWP +I + YL +M+ L KL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Y ++ + LV F+SV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
T G L + DLKCL ++PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I S+L ILP LSCCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
RV E+ TPL+AELM LRE R+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 542 bits (1396), Expect = e-154
Identities = 284/473 (60%), Positives = 335/473 (70%), Gaps = 48/473 (10%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+ YLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
R L++PL
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 542 bits (1396), Expect = e-154
Identities = 284/473 (60%), Positives = 335/473 (70%), Gaps = 48/473 (10%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+ YLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
R L++PL
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
+ +L D++CL +YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
+G V E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 486 bits (1252), Expect = e-137
Identities = 266/473 (56%), Positives = 310/473 (65%), Gaps = 48/473 (10%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
RCL++PLE L L
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252
Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
I S+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 476 bits (1225), Expect = e-134
Identities = 261/478 (54%), Positives = 327/478 (68%), Gaps = 9/478 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MSLQAP RLLELA QSLL D+ALAI L+ELPRELFPPLF+EAFT R CE L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRRWKLQVL+LR+VDENFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+G +H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
CC ++ + ++I +L TV D IQ +E+ C P +++ F+ YL QMRNLRKL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
+ + + D +EQ V +F+S L+L+Y Q LY+ V F GHLDQL+RCL++PLE
Sbjct: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
T+ +T L + DLK L PS+ QLK+L+L L EPL LLE+ ATLQTL L
Sbjct: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
DCGI DS+L ILPALS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
ES D +G + + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 462 bits (1189), Expect = e-130
Identities = 253/474 (53%), Positives = 314/474 (66%), Gaps = 2/474 (0%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+L+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+ YL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
SD +S + +++ V +F++ L+L LQ LY+ V F GHLDQ++ CL++ L LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
+T L + DLK L +YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
GI DS++ ILPALS C LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
D RG V L AELM +R +REP+RI F CP CG LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 462 bits (1189), Expect = e-130
Identities = 253/474 (53%), Positives = 314/474 (66%), Gaps = 2/474 (0%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+L+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+ YL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
SD +S + +++ V +F++ L+L LQ LY+ V F GHLDQ++ CL++ L LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
+T L + DLK L +YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
GI DS++ ILPALS C LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
D RG V L AELM +R +REP+RI F CP CG LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 441 bits (1134), Expect = e-124
Identities = 247/478 (51%), Positives = 320/478 (66%), Gaps = 9/478 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
CC ++ + M I + +L V D IQ +E+ C P +V+F+ YL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
+ + + D++ Q +A F+S L+L+Y Q L + V F GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
+ +T L + DLK L PS+ QLK+L+L L EPL LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
DCGI DS+L ILP LS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
ES D +G + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 441 bits (1134), Expect = e-124
Identities = 247/478 (51%), Positives = 320/478 (66%), Gaps = 9/478 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
CC ++ + M I + +L V D IQ +E+ C P +V+F+ YL QMRNLRKL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
+ + + D++ Q +A F+S L+L+Y Q L + V F GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
+ +T L + DLK L PS+ QLK+L+L L EPL LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
DCGI DS+L ILP LS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
ES D +G + L AELM+ LR++R+PK I F V CP CG + LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 438 bits (1127), Expect = e-123
Identities = 246/478 (51%), Positives = 319/478 (66%), Gaps = 9/478 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
CC ++ + M I + +L V D IQ +E+ C P +V+F+ YL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
+ + + D++ Q +A F+S L+L+Y Q L + V F GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
+ +T L + DLK L PS+ QLK+L+L L EPL LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
DCGI DS+L ILP LS CS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
ES D +G + L AELM+ R++R+PK I F V CP CG + LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 426 bits (1095), Expect = e-119
Identities = 239/476 (50%), Positives = 312/476 (65%), Gaps = 5/476 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
C A ++ V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
CC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
S D RY +S + ++++V +F++ L+L LQ L + V F GHLDQL+ CL++ L+
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
DCGI DS++ ILPALSCC L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
S D G + ++AELM+ +R++R PKRI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 426 bits (1095), Expect = e-119
Identities = 238/474 (50%), Positives = 311/474 (65%), Gaps = 5/474 (1%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPF LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
A C A ++ V+DCPR +QPL VF+++ LK + +DE L++ WV+ R+ +
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
RES G + ++AELM +R++R PKRI F CP CG LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 426 bits (1095), Expect = e-119
Identities = 238/474 (50%), Positives = 311/474 (65%), Gaps = 5/474 (1%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPF LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
A C A ++ V+DCPR +QPL VF+++ LK + +DE L++ WV+ R+ +
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
RES G + ++AELM +R++R PKRI F CP CG LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 422 bits (1084), Expect = e-118
Identities = 238/476 (50%), Positives = 311/476 (65%), Gaps = 5/476 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
C A ++ V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
CC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
S D RY +S + ++++V +F++ L+L LQ L + V F GHLDQL+ CL++ L+
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
DCGI DS++ ILPALS C L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
S D G + ++AELM+ +R++R PKRI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 421 bits (1083), Expect = e-118
Identities = 238/476 (50%), Positives = 310/476 (65%), Gaps = 5/476 (1%)
Query: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
C A + V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
CC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
S D RY +S + ++++V +F++ L+L LQ L + V F GHLDQL+ CL++ L+
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
DCGI DS++ ILPALS C L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
S D G + ++AELM+ +R++R PKRI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 420 bits (1079), Expect = e-117
Identities = 237/474 (50%), Positives = 309/474 (65%), Gaps = 5/474 (1%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
M+MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPF LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
A C A + V+DCPR E+QPL VF+++ LK + +DE L+ WV+ RR +
Sbjct: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL +RNL+KL
Sbjct: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKL 274
Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 275 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 333
Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 334 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 393
Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL LE YPAP
Sbjct: 394 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAP 453
Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
+ES G + ++AELM+ +R +R PKRI F +CP G LE
Sbjct: 454 QESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 419 bits (1077), Expect = e-117
Identities = 237/474 (50%), Positives = 308/474 (64%), Gaps = 5/474 (1%)
Query: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
M+MS+ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+
Sbjct: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
Query: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
WPF LPL L+K P LE V+DG+D LL VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
A C A ++ VEDCPR +QPL VF+++ LK + +DE L+ WV+ R+ +
Sbjct: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 ILSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 299 KFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
RES G + ++AELM +R++R PKRI F CP CG LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 362 bits (929), Expect = e-100
Identities = 208/432 (48%), Positives = 273/432 (63%), Gaps = 5/432 (1%)
Query: 43 VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 102
+EAF+ RRCE LK+MVQAWPF LPL L+K P LE V+DG+D LL Q VRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 103 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 162
QVL+L+DV ENFW +WS A C A + V+DCPR E+QPL VF+++ LK + +
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 163 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 222
DE L+ WV+ RR +HLCC K+ M N R+IL+ V D IQ +E+ N W
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
Query: 223 IV-EFSRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRV 279
I+ +F+ YL +RNL+KL +S D RY+ S + ++++V +F++ L+L LQ LY+ V
Sbjct: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
Query: 280 CFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRL 339
F GHLDQL+ CL++ L+ L +T L + DLK L + PS+SQLK L+LS L L
Sbjct: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
Query: 340 EPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDL 399
PL+ LLEKVAATL+ L L DCGI DS++ ILPALS C L TF F GN M L++L
Sbjct: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
Query: 400 LRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSC 459
L HT L NL LE YPAP+ES G + ++AELM+ +R +R PKRI F +C
Sbjct: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
Query: 460 PCCGTSPTEQLE 471
P G LE
Sbjct: 419 PDHGDRSFYDLE 430
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 360 bits (923), Expect = 2e-99
Identities = 216/470 (45%), Positives = 295/470 (62%), Gaps = 13/470 (2%)
Query: 7 APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66
+PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF R + LK MVQAWPF CL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 67 PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLELR-DVDENFWTIWSGARP 123
PLG LMK L E V+DG+D LLAQ+VRPRRWKLQVL+LR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175
S PEA M+K++ V+ E+ P++V +D+ LKE DE S+ V+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRN 235
++ + LCC K+ ++M + + + IL+ V DSI+ LE+ + +FS YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294
LR+L +S +S + +EQ +A+F+S L L+ LQ LYV + F RG LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354
+PLETL++T L + D+ L + PS+SQL L+LS L + EPL+ALLE+ +ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414
L +CGI D +L +LP+LS CS LTT F+GN S+ L+ LL+H LSNL+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463
P P ES +D G + E L L A L +L E+ P ++ CP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 360 bits (923), Expect = 2e-99
Identities = 216/470 (45%), Positives = 295/470 (62%), Gaps = 13/470 (2%)
Query: 7 APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66
+PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF R + LK MVQAWPF CL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 67 PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLELR-DVDENFWTIWSGARP 123
PLG LMK L E V+DG+D LLAQ+VRPRRWKLQVL+LR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175
S PEA M+K++ V+ E+ P++V +D+ LKE DE S+ V+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRN 235
++ + LCC K+ ++M + + + IL+ V DSI+ LE+ + +FS YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294
LR+L +S +S + +EQ +A+F+S L L+ LQ LYV + F RG LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354
+PLETL++T L + D+ L + PS+SQL L+LS L + EPL+ALLE+ +ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414
L +CGI D +L +LP+LS CS LTT F+GN S+ L+ LL+H LSNL+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463
P P ES +D G + E L L A L +L E+ P ++ CP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,247,504
Number of Sequences: 37866
Number of extensions: 799084
Number of successful extensions: 2449
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2320
Number of HSP's gapped (non-prelim): 65
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.