Guide to the Human Genome
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Search of human proteins with 154800493

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154800493 PRAME family member 22 [Homo sapiens]
         (481 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154800493 PRAME family member 22 [Homo sapiens]                    979   0.0  
gi|194306638 PRAME family member 3 [Homo sapiens]                     972   0.0  
gi|153791443 PRAME family member 18 [Homo sapiens]                    895   0.0  
gi|194306635 PRAME family member 19 [Homo sapiens]                    892   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    695   0.0  
gi|194018546 PRAME family member 10 [Homo sapiens]                    585   e-167
gi|157426839 PRAME family member 17 [Homo sapiens]                    571   e-163
gi|113865933 PRAME family member 16 [Homo sapiens]                    569   e-162
gi|12738831 PRAME family member 1 [Homo sapiens]                      561   e-160
gi|66954681 PRAME family member 13 [Homo sapiens]                     552   e-157
gi|12738834 PRAME family member 2 [Homo sapiens]                      545   e-155
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ...   542   e-154
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ...   542   e-154
gi|153792140 PRAME family member 14 [Homo sapiens]                    486   e-137
gi|124249372 PRAME family member 12 [Homo sapiens]                    476   e-134
gi|153792112 PRAME family member 20 [Homo sapiens]                    462   e-130
gi|153945800 PRAME family member 21 [Homo sapiens]                    462   e-130
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   441   e-124
gi|59676587 PRAME family member 8 [Homo sapiens]                      441   e-124
gi|59676593 PRAME family member 7 [Homo sapiens]                      438   e-123
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         426   e-119
gi|148356236 PRAME family member 15 [Homo sapiens]                    426   e-119
gi|61102721 PRAME family member 9 [Homo sapiens]                      426   e-119
gi|61696142 PRAME family member 5 [Homo sapiens]                      422   e-118
gi|58219004 PRAME family member 6 [Homo sapiens]                      421   e-118
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         420   e-117
gi|59958373 PRAME family member 4 [Homo sapiens]                      419   e-117
gi|226437621 PRAME family member 11 [Homo sapiens]                    362   e-100
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   360   2e-99
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   360   2e-99

>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  979 bits (2532), Expect = 0.0
 Identities = 481/481 (100%), Positives = 481/481 (100%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA
Sbjct: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG
Sbjct: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240
           HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240

Query: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
           ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL
Sbjct: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300

Query: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
           ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD
Sbjct: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360

Query: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
           CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES
Sbjct: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420

Query: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
           LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP
Sbjct: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480

Query: 481 A 481
           A
Sbjct: 481 A 481


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  972 bits (2512), Expect = 0.0
 Identities = 479/481 (99%), Positives = 479/481 (99%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA
Sbjct: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLELRDVDENFWTIWSG
Sbjct: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSG 120

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLF 240
           HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEF RYLSQMRNLRKLF
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLF 240

Query: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300
           ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL
Sbjct: 241 ISDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETL 300

Query: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360
           ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD
Sbjct: 301 ALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVD 360

Query: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420
           CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES
Sbjct: 361 CGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRES 420

Query: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480
           LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP
Sbjct: 421 LDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRP 480

Query: 481 A 481
           A
Sbjct: 481 A 481


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  895 bits (2313), Expect = 0.0
 Identities = 442/479 (92%), Positives = 456/479 (95%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
           DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I DSKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
           +RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  892 bits (2304), Expect = 0.0
 Identities = 441/479 (92%), Positives = 455/479 (94%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
           DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I  SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
           +RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  695 bits (1793), Expect = 0.0
 Identities = 360/469 (76%), Positives = 387/469 (82%), Gaps = 1/469 (0%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLELRDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFS YLSQMRNLRKLFIS
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
           DGCRYLLSSDSQEQ +A F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L+ L +
Sbjct: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L DCG
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I DS++  ILPALS C  L TF F GN  SM  L++LL HT  L NL LE YPAPRES  
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
             G +     T ++AELM+ +R++R PKRI FG   CP CG      LE
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  585 bits (1508), Expect = e-167
 Identities = 298/473 (63%), Positives = 359/473 (75%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQAP RLLELAGQSLL +Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMKT  LE L  V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61  FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE  +DE LS+  GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      +F+ YLSQM NLR+LF++
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
            G    L    Q   + +  S  L L Y QMLY++++   + HL+ L+R L++PL     
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           +  +L   D++CL +YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
            +G V  E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  571 bits (1472), Expect = e-163
 Identities = 294/473 (62%), Positives = 354/473 (74%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE  +DE LS+   W+ +RRG VHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      +F+ YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
            G    L    Q+Q V +     L L Y QMLY+R++   + HL+ L+RCL++PL T   
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
            + +L   D++CL +YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           +RG V  E+L P++AELM  LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  569 bits (1467), Expect = e-162
 Identities = 293/473 (61%), Positives = 353/473 (74%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL+LRDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE  +DE LS+   W+ +RRG VHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      +F+ YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
            G    L    Q+Q V +     L L Y QMLY+R++   + HL+ L+RCL++PL T   
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
            + +L   D++CL +YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I+DS+LRV+LPALS CS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           +RG V  E+L P++AELM  LREVR+PKRIFFGP+ CP CG+ P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  561 bits (1447), Expect = e-160
 Identities = 293/473 (61%), Positives = 348/473 (73%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL+LRDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSC PE  SKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RRG VHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+K+VNY   I   R  L+ +Y +SIQ LEI NM WP +I +   YL +M+NLRKL  S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
               Y   ++ Q +LVA+FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           TYG+L + D+KCL +YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I  S+L  ILPALS CS LTTF F  N  S+D LKDLLRHT  LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
              RV  E+ TPL+AELM  LREVR+PKRIF GP  CP CG+SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  552 bits (1422), Expect = e-157
 Identities = 291/474 (61%), Positives = 346/474 (72%), Gaps = 2/474 (0%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF  R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL+LRDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+K+VNY   I + R  L+ +Y +SIQ LEI NM WP +I +   YL +M+NLRKL  S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 243 DGCRYLLSSDSQE-QLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
             C + +S +  E +LV +FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L 
Sbjct: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299

Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
           LTYG+L + D+KCL +YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359

Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
            I  S+L  ILP LS CS LTTF F  N  SM  LKDLLRHT  LS LSLETYPAP ESL
Sbjct: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419

Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           +   RV  E+   L+AELM  LREVR+PKRIF GP  CP CG+SP+E+LE + C
Sbjct: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|12738834 PRAME family member 2 [Homo sapiens]
          Length = 474

 Score =  545 bits (1405), Expect = e-155
 Identities = 287/473 (60%), Positives = 340/473 (71%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F CLPL SLMKT  LE L  +++G+  LL QK RPRRWKLQVL+LRDVDENFW  W GA 
Sbjct: 61  FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE   DE L +   WV  RRG VHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+K+VNY   I   R  L+ +Y +SI  LEI N CWP +I +   YL +M+ L KL  S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
               Y   ++ +  LV  F+SV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           T G L + DLKCL ++PSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I  S+L  ILP LSCCS LTTF F  N  S+D LKDLLRHT  LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
              RV  E+ TPL+AELM  LRE R+PKRIF GP  CP CG+SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  542 bits (1396), Expect = e-154
 Identities = 284/473 (60%), Positives = 335/473 (70%), Gaps = 48/473 (10%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQAP RLLELAGQSLL +Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMKTP LE L  V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE  +DE LS+  GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      +F+ YLSQM NLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
                                                           R L++PL     
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           +  +L   D++CL +YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT  LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
            +G V  E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425


>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  542 bits (1396), Expect = e-154
 Identities = 284/473 (60%), Positives = 335/473 (70%), Gaps = 48/473 (10%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQAP RLLELAGQSLL +Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMKTP LE L  V+ G+D L+AQKVRPRRWKLQVL+LRDVDENFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE  +DE LS+  GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      +F+ YLSQM NLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
                                                           R L++PL     
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           +  +L   D++CL +YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I+D +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT  LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
            +G V  E+LTP++AELMR LREVR+PKRIFFGPV CP CG+ P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425


>gi|153792140 PRAME family member 14 [Homo sapiens]
          Length = 426

 Score =  486 bits (1252), Expect = e-137
 Identities = 266/473 (56%), Positives = 310/473 (65%), Gaps = 48/473 (10%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF  R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL+LRDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
           CC+K+VNY   I + R  L+ +Y +SIQ LEI NM WP +I +   YL +M+NLRKL  S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
                                                           RCL++PLE L L
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252

Query: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
           TYG+L + D+KCL +YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312

Query: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
           I  S+L  ILP LS CS LTTF F  N  SM  LKDLL HT  LS LSLETYPAP ESL+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372

Query: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
              RV  E+   L+AELM  LREVR+PKRIF GP  CP CG+SP+E+LE + C
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  476 bits (1225), Expect = e-134
 Identities = 261/478 (54%), Positives = 327/478 (68%), Gaps = 9/478 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MSLQAP RLLELA QSLL D+ALAI  L+ELPRELFPPLF+EAFT R CE L  MVQAWP
Sbjct: 1   MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F CLPLGSLMK+ +LEI   V++G+D LLAQKVRPRRWKLQVL+LR+VDENFW IWSGA 
Sbjct: 61  FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
            LS  PEA+SKR+T  +CPR G +QPL V +D+C K   +DE L+ F  W + R+G +H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
           CC ++  + ++I     +L TV  D IQ +E+   C P    +++ F+ YL QMRNLRKL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235

Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
            + +      +  D +EQ V +F+S  L+L+Y Q LY+  V F  GHLDQL+RCL++PLE
Sbjct: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295

Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
           T+ +T   L + DLK L   PS+ QLK+L+L    L     EPL  LLE+  ATLQTL L
Sbjct: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355

Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
            DCGI DS+L  ILPALS CS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP 
Sbjct: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415

Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
           ES D +G +     + L AELM+ LR++R+PK I F  V CP CG   +  LE + CL
Sbjct: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCL 473


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  462 bits (1189), Expect = e-130
 Identities = 253/474 (53%), Positives = 314/474 (66%), Gaps = 2/474 (0%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMK P  E    V+DG+D LL  +VR RRWKLQVL+L+DV ENFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
              C P AM  R+ V+DCPR   +QPL VF+D+CLK + +DE  +    WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
           CC K+    M   N RNIL+TV  D IQ +E+ N  W   ++ EF+ YL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239

Query: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
           SD     +S + +++ V +F++  L+L  LQ LY+  V F  GHLDQ++ CL++ L  LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
           +T   L + DLK L +YPS+ QLK L+LS   L    L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
           GI DS++  ILPALS C  LTTF F GN  S   L++LL HT RL+NL LE YPAPRES 
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           D RG V       L AELM  +R +REP+RI F    CP CG      LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  462 bits (1189), Expect = e-130
 Identities = 253/474 (53%), Positives = 314/474 (66%), Gaps = 2/474 (0%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMK P  E    V+DG+D LL  +VR RRWKLQVL+L+DV ENFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
              C P AM  R+ V+DCPR   +QPL VF+D+CLK + +DE  +    WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
           CC K+    M   N RNIL+TV  D IQ +E+ N  W   ++ EF+ YL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239

Query: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
           SD     +S + +++ V +F++  L+L  LQ LY+  V F  GHLDQ++ CL++ L  LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
           +T   L + DLK L +YPS+ QLK L+LS   L    L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
           GI DS++  ILPALS C  LTTF F GN  S   L++LL HT RL+NL LE YPAPRES 
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           D RG V       L AELM  +R +REP+RI F    CP CG      LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  441 bits (1134), Expect = e-124
 Identities = 247/478 (51%), Positives = 320/478 (66%), Gaps = 9/478 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL+LR+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK + +DE L+    W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
           CC ++  + M I +   +L  V  D IQ +E+   C P     +V+F+ YL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
            + +      +  D++ Q +A F+S  L+L+Y Q L +  V F  GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295

Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
            + +T   L + DLK L   PS+ QLK+L+L    L     EPL  LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355

Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
            DCGI DS+L  ILP LS CS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP 
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415

Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
           ES D +G +       L AELM+ LR++R+PK I F  V CP CG   +  LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  441 bits (1134), Expect = e-124
 Identities = 247/478 (51%), Positives = 320/478 (66%), Gaps = 9/478 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL+LR+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK + +DE L+    W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
           CC ++  + M I +   +L  V  D IQ +E+   C P     +V+F+ YL QMRNLRKL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
            + +      +  D++ Q +A F+S  L+L+Y Q L +  V F  GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295

Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
            + +T   L + DLK L   PS+ QLK+L+L    L     EPL  LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355

Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
            DCGI DS+L  ILP LS CS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP 
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415

Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
           ES D +G +       L AELM+ LR++R+PK I F  V CP CG   +  LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  438 bits (1127), Expect = e-123
 Identities = 246/478 (51%), Positives = 319/478 (66%), Gaps = 9/478 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL+LR+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK + +DE L+    W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSRYLSQMRNLRKL 239
           CC ++  + M I +   +L  V  D IQ +E+   C P     +V+F+ YL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 240 FISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLE 298
            + +      +  D++ Q +A F+S  L+L+Y Q L +  V F  GHLDQL+RCL++ LE
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295

Query: 299 TLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFL 358
            + +T   L + DLK L   PS+ QLK+L+L    L     EPL  LLE+V ATLQTL L
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355

Query: 359 VDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPR 418
            DCGI DS+L  ILP LS CS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP 
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415

Query: 419 ESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCL 476
           ES D +G +       L AELM+  R++R+PK I F  V CP CG   +  LE + CL
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  426 bits (1095), Expect = e-119
 Identities = 239/476 (50%), Positives = 312/476 (65%), Gaps = 5/476 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
              C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
           S  D  RY +S + ++++V +F++  L+L  LQ L +  V F  GHLDQL+ CL++ L+ 
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
           L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
           DCGI DS++  ILPALSCC  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           S D  G +       ++AELM+ +R++R PKRI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  426 bits (1095), Expect = e-119
 Identities = 238/474 (50%), Positives = 311/474 (65%), Gaps = 5/474 (1%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS 
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           A    C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L++   WV+ R+  +
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239

Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298

Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358

Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418

Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
           RES    G +       ++AELM  +R++R PKRI F    CP CG      LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  426 bits (1095), Expect = e-119
 Identities = 238/474 (50%), Positives = 311/474 (65%), Gaps = 5/474 (1%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           M+MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1   MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS 
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           A    C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L++   WV+ R+  +
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239

Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 240 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298

Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 299 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358

Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418

Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
           RES    G +       ++AELM  +R++R PKRI F    CP CG      LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  422 bits (1084), Expect = e-118
 Identities = 238/476 (50%), Positives = 311/476 (65%), Gaps = 5/476 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
              C   A   ++ V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
           S  D  RY +S + ++++V +F++  L+L  LQ L +  V F  GHLDQL+ CL++ L+ 
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
           L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
           DCGI DS++  ILPALS C  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           S D  G +       ++AELM+ +R++R PKRI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  421 bits (1083), Expect = e-118
 Identities = 238/476 (50%), Positives = 310/476 (65%), Gaps = 5/476 (1%)

Query: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
              C   A   +  V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299
           S  D  RY +S + ++++V +F++  L+L  LQ L +  V F  GHLDQL+ CL++ L+ 
Sbjct: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359
           L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419
           DCGI DS++  ILPALS C  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
           S D  G +       ++AELM+ +R++R PKRI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  420 bits (1079), Expect = e-117
 Identities = 237/474 (50%), Positives = 309/474 (65%), Gaps = 5/474 (1%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           M+MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 36  MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS 
Sbjct: 96  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           A    C   A   +  V+DCPR  E+QPL VF+++ LK + +DE L+    WV+ RR  +
Sbjct: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  +RNL+KL
Sbjct: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKL 274

Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 275 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 333

Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 334 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 393

Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL LE YPAP
Sbjct: 394 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAP 453

Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
           +ES    G +       ++AELM+ +R +R PKRI F   +CP  G      LE
Sbjct: 454 QESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  419 bits (1077), Expect = e-117
 Identities = 237/474 (50%), Positives = 308/474 (64%), Gaps = 5/474 (1%)

Query: 1   MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
           M+MS+  P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+
Sbjct: 1   MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60

Query: 61  WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
           WPF  LPL  L+K P LE    V+DG+D LL   VRPRRWKLQVL+L+DV ENFW +WS 
Sbjct: 61  WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120

Query: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
           A    C   A   ++ VEDCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +
Sbjct: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180

Query: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
           HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239

Query: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
            +S  D  RY +S + ++++V +F++  L+L  LQ LY+  V F  GHLDQL+ CL++ L
Sbjct: 240 ILSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298

Query: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
           + L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L 
Sbjct: 299 KFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358

Query: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
           L DCGI DS++  ILPALS C  L TF F GN   M  L++LL HT  L NL +E YPAP
Sbjct: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418

Query: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
           RES    G +       ++AELM  +R++R PKRI F    CP CG      LE
Sbjct: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  362 bits (929), Expect = e-100
 Identities = 208/432 (48%), Positives = 273/432 (63%), Gaps = 5/432 (1%)

Query: 43  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 102
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 103 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 162
           QVL+L+DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK + +
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 163 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 222
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179

Query: 223 IV-EFSRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRV 279
           I+ +F+ YL  +RNL+KL +S  D  RY+ S + ++++V +F++  L+L  LQ LY+  V
Sbjct: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238

Query: 280 CFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRL 339
            F  GHLDQL+ CL++ L+ L +T   L + DLK L + PS+SQLK L+LS   L    L
Sbjct: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298

Query: 340 EPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDL 399
            PL+ LLEKVAATL+ L L DCGI DS++  ILPALS C  L TF F GN   M  L++L
Sbjct: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358

Query: 400 LRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSC 459
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R PKRI F   +C
Sbjct: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418

Query: 460 PCCGTSPTEQLE 471
           P  G      LE
Sbjct: 419 PDHGDRSFYDLE 430


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  360 bits (923), Expect = 2e-99
 Identities = 216/470 (45%), Positives = 295/470 (62%), Gaps = 13/470 (2%)

Query: 7   APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66
           +PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF  R  + LK MVQAWPF CL
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 67  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLELR-DVDENFWTIWSGARP 123
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL+LR +  ++FWT+WSG R 
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175
              S   PEA   M+K++ V+      E+   P++V +D+ LKE   DE  S+    V+ 
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRN 235
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        + +FS YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294
           LR+L +S       +S + +EQ +A+F+S  L L+ LQ LYV  + F RG LDQL+R + 
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321

Query: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354
           +PLETL++T   L + D+  L + PS+SQL  L+LS   L  +  EPL+ALLE+ +ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381

Query: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414
            L   +CGI D +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441

Query: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463
           P P ES +D  G +  E L  L A L  +L E+  P  ++     CP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  360 bits (923), Expect = 2e-99
 Identities = 216/470 (45%), Positives = 295/470 (62%), Gaps = 13/470 (2%)

Query: 7   APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66
           +PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF  R  + LK MVQAWPF CL
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 67  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLELR-DVDENFWTIWSGARP 123
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL+LR +  ++FWT+WSG R 
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175
              S   PEA   M+K++ V+      E+   P++V +D+ LKE   DE  S+    V+ 
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRN 235
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        + +FS YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294
           LR+L +S       +S + +EQ +A+F+S  L L+ LQ LYV  + F RG LDQL+R + 
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321

Query: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354
           +PLETL++T   L + D+  L + PS+SQL  L+LS   L  +  EPL+ALLE+ +ATLQ
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381

Query: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414
            L   +CGI D +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441

Query: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463
           P P ES +D  G +  E L  L A L  +L E+  P  ++     CP CG
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,247,504
Number of Sequences: 37866
Number of extensions: 799084
Number of successful extensions: 2449
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2320
Number of HSP's gapped (non-prelim): 65
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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