Guide to the Human Genome
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Search of human proteins with 15451852

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15451852 midline 1 [Homo sapiens]
         (667 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148833499 midline 1 [Homo sapiens]                                1367   0.0  
gi|4557753 midline 1 [Homo sapiens]                                  1367   0.0  
gi|15451852 midline 1 [Homo sapiens]                                 1367   0.0  
gi|223890259 midline 2 isoform 2 [Homo sapiens]                      1090   0.0  
gi|223890257 midline 2 isoform 1 [Homo sapiens]                      1074   0.0  
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   230   4e-60
gi|89886468 fibronectin type III and SPRY domain containing 1-li...   217   2e-56
gi|223718222 fibronectin type III and SPRY domain containing 1-l...   214   2e-55
gi|47174859 tripartite motif-containing 46 [Homo sapiens]             213   6e-55
gi|13236585 fibronectin type III and SPRY domain containing 1 [H...   210   3e-54
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]      193   5e-49
gi|134288906 tripartite motif-containing 67 [Homo sapiens]            189   7e-48
gi|68160937 tripartite motif-containing 25 [Homo sapiens]             152   1e-36
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]      149   6e-36
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]       149   1e-35
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]           126   7e-29
gi|55741632 fibronectin type III and SPRY domain containing 2 [H...   124   4e-28
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]           123   6e-28
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]   122   8e-28
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]   122   8e-28
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]   122   8e-28
gi|28195390 tripartite motif-containing 42 [Homo sapiens]             103   5e-22
gi|148596968 tripartite motif-containing 8 [Homo sapiens]              97   4e-20
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    96   1e-19
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    96   1e-19
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    96   1e-19
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       90   6e-18
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 90   8e-18
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...    89   1e-17
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...    89   1e-17

>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score = 1367 bits (3539), Expect = 0.0
 Identities = 667/667 (100%), Positives = 667/667 (100%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
           METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR
Sbjct: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60

Query: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
           HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ
Sbjct: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120

Query: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
           FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180

Query: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
           EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240

Query: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
           LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300

Query: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
           NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360

Query: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
           TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420

Query: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
           FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480

Query: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
           TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540

Query: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
           HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600

Query: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
           LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660

Query: 661 DCTEQLP 667
           DCTEQLP
Sbjct: 661 DCTEQLP 667


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score = 1367 bits (3539), Expect = 0.0
 Identities = 667/667 (100%), Positives = 667/667 (100%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
           METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR
Sbjct: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60

Query: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
           HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ
Sbjct: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120

Query: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
           FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180

Query: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
           EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240

Query: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
           LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300

Query: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
           NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360

Query: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
           TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420

Query: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
           FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480

Query: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
           TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540

Query: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
           HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600

Query: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
           LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660

Query: 661 DCTEQLP 667
           DCTEQLP
Sbjct: 661 DCTEQLP 667


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score = 1367 bits (3539), Expect = 0.0
 Identities = 667/667 (100%), Positives = 667/667 (100%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
           METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR
Sbjct: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60

Query: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
           HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ
Sbjct: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120

Query: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
           FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180

Query: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
           EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240

Query: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
           LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300

Query: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
           NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360

Query: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
           TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420

Query: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
           FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK
Sbjct: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480

Query: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
           TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
Sbjct: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540

Query: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
           HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH
Sbjct: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600

Query: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
           LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL
Sbjct: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660

Query: 661 DCTEQLP 667
           DCTEQLP
Sbjct: 661 DCTEQLP 667


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score = 1090 bits (2819), Expect = 0.0
 Identities = 507/665 (76%), Positives = 590/665 (88%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
           METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 21  METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80

Query: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
           +VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER +   T  S+E++ CQ
Sbjct: 81  YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140

Query: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
           FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200

Query: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
           EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE  
Sbjct: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260

Query: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
           +AKLIQ CQ VEVN +  EAKL EECD L+EIIQQR+Q+I  KIKE KVM+LRKLAQQ+A
Sbjct: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320

Query: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
           NC+QC+ERS  LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380

Query: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
            FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440

Query: 421 FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK 480
           FTGQAN +SL NS DSWMIVPNIKQNHYTVHGLQSGT+YIF+VKAINQAGSR+SEP +LK
Sbjct: 441 FTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLK 500

Query: 481 TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR 540
           TNSQPFKLDPK  H+KLK+S+D L +E+DESS KKSHTPERF+  G YG AGN+FIDSG 
Sbjct: 501 TNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGC 560

Query: 541 HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH 600
           HYWEVV+  STWYAIG+AYKSAPK+EWIGKN++SW   RCN+N+VVRHN+KE+ ++  PH
Sbjct: 561 HYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPH 620

Query: 601 LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL 660
           L+R+G+LLDYDN  ++FYD  NS+HL+TFDV F  PVCPTFT+WNK L I++GLP PD +
Sbjct: 621 LKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 680

Query: 661 DCTEQ 665
           D  E+
Sbjct: 681 DYPER 685


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score = 1074 bits (2778), Expect = 0.0
 Identities = 507/695 (72%), Positives = 590/695 (84%), Gaps = 30/695 (4%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
           METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 21  METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80

Query: 61  HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
           +VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER +   T  S+E++ CQ
Sbjct: 81  YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140

Query: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
           FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200

Query: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
           EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE  
Sbjct: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260

Query: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
           +AKLIQ CQ VEVN +  EAKL EECD L+EIIQQR+Q+I  KIKE KVM+LRKLAQQ+A
Sbjct: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320

Query: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
           NC+QC+ERS  LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380

Query: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
            FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440

Query: 421 FTGQANVVS------------------------------LCNSADSWMIVPNIKQNHYTV 450
           FTGQAN +S                              L NS DSWMIVPNIKQNHYTV
Sbjct: 441 FTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTV 500

Query: 451 HGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDE 510
           HGLQSGT+YIF+VKAINQAGSR+SEP +LKTNSQPFKLDPK  H+KLK+S+D L +E+DE
Sbjct: 501 HGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDE 560

Query: 511 SSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGK 570
           SS KKSHTPERF+  G YG AGN+FIDSG HYWEVV+  STWYAIG+AYKSAPK+EWIGK
Sbjct: 561 SSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGK 620

Query: 571 NSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFD 630
           N++SW   RCN+N+VVRHN+KE+ ++  PHL+R+G+LLDYDN  ++FYD  NS+HL+TFD
Sbjct: 621 NASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFD 680

Query: 631 VAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQ 665
           V F  PVCPTFT+WNK L I++GLP PD +D  E+
Sbjct: 681 VTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPER 715


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  230 bits (586), Expect = 4e-60
 Identities = 183/725 (25%), Positives = 308/725 (42%), Gaps = 125/725 (17%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL---------VSHCATNESVESI 51
           ++ +E EL CP C ELF  PL+LPC HS+C  C   +L         V    +N+S   +
Sbjct: 24  IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83

Query: 52  ---------------------------TAFQCPTCRHVITLSQRGLDGLKRNVTLQNIID 84
                                      T F CP C H + L +RG++GL RN TL+ I++
Sbjct: 84  RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143

Query: 85  RFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDE 144
           R+++A+                      +A  ++C  C + P Q++ K+C+ C  SYC+E
Sbjct: 144 RYRQAA---------------------RAATAIMCDLC-KPPPQESTKSCMDCSASYCNE 181

Query: 145 CLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRH 204
           C K  HP       H  + P  +   + LMC EHE E++NMYC    + +C LCKL G H
Sbjct: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241

Query: 205 RDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE 264
            +H+V  +S  Y  LK+ L  ++  LI + +++++ +++L    +  E N  R + +   
Sbjct: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301

Query: 265 ECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKEND 324
             + L E++++R+  +   I   K +RL K   Q+   +  +E +  L+  A+  LKE D
Sbjct: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETD 360

Query: 325 HARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAP-N 383
            + F+QTAK +  R+  AT S +   P      +F+ + ++ S++ +LL  L + ++  +
Sbjct: 361 QSCFVQTAKQLHLRIQKATESLKSFRPA--AQTSFEDYVVNTSKQTELLGELSFFSSGID 418

Query: 384 PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQA----NVVSLCNSADSWMI 439
            P I EE  +  Y+   ++W   ++    SY L+Y           N + +C ++     
Sbjct: 419 VPEINEEQ-SKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSK---- 473

Query: 440 VPNIKQNHYTVHGLQSGTKYIFMVKAI-NQAGSRSSEPGKLKTNSQP---FKLDPKSAHR 495
                     +  L++ + Y F V+A      S  S    L T   P   F  D K  + 
Sbjct: 474 ---------IIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524

Query: 496 KLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG-------VAGNVFIDSGRHYWEVVIS 548
                H  L ++RD   S+          +   G       + G+  I  G+H+W   + 
Sbjct: 525 N---EHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVE 581

Query: 549 GSTWYAIGLAYKSAPK-HEWI---------------GKNSASWALCRCNNN----WVVRH 588
             + Y + +   S+ K  EW+               G +S S   C  ++       +  
Sbjct: 582 PYS-YLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGM 640

Query: 589 NSKEIPIEPA----------PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 638
               IP  P           P    +GI LD D G + FYD      LY   V  +  + 
Sbjct: 641 QKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLY 700

Query: 639 PTFTV 643
           P F +
Sbjct: 701 PAFAL 705


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score =  217 bits (553), Expect = 2e-56
 Identities = 150/483 (31%), Positives = 245/483 (50%), Gaps = 54/483 (11%)

Query: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276
           D  K+ L+  ++ L  +N E++  +  L  T + V+ N+S   ++L EE D L  I+ + 
Sbjct: 2   DSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEV 61

Query: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336
           ++ +   IK+ +  + ++L  QI+ C   +E S  L+  A  SL   +   F + A+ I 
Sbjct: 62  KESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIK 121

Query: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396
           +RV+MA+A    L P++  +D      +DFS+E+++L+ L +L  P  P I    C  + 
Sbjct: 122 DRVTMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVAD 179

Query: 397 DTITVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453
           +++TV W   +E + + +   E + T F G   V         W I+ NIK   YT+ GL
Sbjct: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGL 235

Query: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511
           +  +KY+ F V+A N+A     S+P  L+T +  F LD  S+H  LKV  ++  VE D +
Sbjct: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPT 293

Query: 512 SSK-------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGR 540
             K             +S TP                  +RFT + SY V G+  I+SG+
Sbjct: 294 GGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQ 352

Query: 541 HYWEV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIP 594
           HYWEV        Y++G+AYK+  K + +GK + SW  C   NNW+      +HN+K   
Sbjct: 353 HYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKA 410

Query: 595 IEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGL 654
           ++      ++G+  D+D G ++FYDA +   LY+F   F QPV P F VW   L++ TG+
Sbjct: 411 LDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGM 469

Query: 655 PIP 657
            +P
Sbjct: 470 QVP 472


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score =  214 bits (545), Expect = 2e-55
 Identities = 148/480 (30%), Positives = 244/480 (50%), Gaps = 54/480 (11%)

Query: 220 KQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQI 279
           ++ L+  ++ L  +N E++  +  L  T + V+ N+S   ++L EE D L  I+ + ++ 
Sbjct: 37  QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96

Query: 280 IGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERV 339
           +   IK+ +  + ++L  QI+ C   +E S  L+  A  SL   +   F + A+ I +RV
Sbjct: 97  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156

Query: 340 SMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTI 399
           +MA+A    L P++  +D      +DFS+E+++L+ L +L  P  P I    C  + +++
Sbjct: 157 TMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214

Query: 400 TVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSG 456
           TV W   +E + + +   E + T F G   V         W I+ NIK   YT+ GL+  
Sbjct: 215 TVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGLKFD 270

Query: 457 TKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSK 514
           +KY+ F V+A N+A     S+P  L+T +  F LD  S+H  LKV  ++  VE D +  K
Sbjct: 271 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPTGGK 328

Query: 515 -------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGRHYW 543
                        +S TP                  +RFT + SY V G+  I+SG+HYW
Sbjct: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQHYW 387

Query: 544 EV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIPIEP 597
           EV        Y++G+AYK+  K + +GK + SW  C   NNW+      +HN+K   ++ 
Sbjct: 388 EVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKALDV 445

Query: 598 APHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIP 657
                ++G+  D+D G ++FYDA +   LY+F   F QPV P F VW   L++ TG+ +P
Sbjct: 446 TVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVP 504


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score =  213 bits (541), Expect = 6e-55
 Identities = 183/743 (24%), Positives = 311/743 (41%), Gaps = 140/743 (18%)

Query: 1   METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL-----VSHC----------ATN 45
           M+ +E EL CP+C E+++ PL+LPC H++C  CA  +L     + H           A+ 
Sbjct: 24  MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83

Query: 46  ESVES------------------------------------ITAFQCPTCRHVITLSQRG 69
            S  S                                    +  F CP C+  + L +RG
Sbjct: 84  PSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERG 143

Query: 70  LDGLKRNVTLQNIIDRF-QKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQ 128
           L GL RN+TL+ +++R+ Q  SV G                       +LCQ C + P  
Sbjct: 144 LAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLC-KPPPL 180

Query: 129 DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCV 188
           +A K C  C  ++C+EC K  HP       H    P      +GLMC +H++E V  YC 
Sbjct: 181 EATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHKEE-VTHYCK 239

Query: 189 TDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTC 248
           T  +L+C LC++   H  H++  +   Y  LK  L  +LT ++     ++T + +L +  
Sbjct: 240 TCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAV 299

Query: 249 QHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIER 308
           +H EV+  + + ++++    L  +++++R  +   I+E +  RL +L+ QI   +  ++ 
Sbjct: 300 RHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDG 359

Query: 309 SASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSR 368
           S  L+  A+  LKE D   F+Q AK +  R++ AT + Q   P    + +F    LD  R
Sbjct: 360 S-GLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPA--ASSSFRHCQLDVGR 416

Query: 369 EKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV 428
           E KLL  L++L  P  P I  +  T +YD I + W          +   YT+   + +V 
Sbjct: 417 EMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCWRLPPHSPPAWH---YTVEFRRTDVP 472

Query: 429 SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQP-- 485
           +       W     ++     +    +G+ Y+  V+  N+AG    SE   L T   P  
Sbjct: 473 AQ-PGPTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVL 531

Query: 486 -FKLDPK--SAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG---VAGNVFIDSG 539
            F LD +  ++  +L +S D   V R           +R  +        V G+V +  G
Sbjct: 532 HFFLDSRWGASRERLAISKDQRAV-RSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQG 590

Query: 540 RHYWEVVISGSTWYA-IGLAYKS-------------APKHE------------------- 566
           R YW   +  +++   +G+  +S             +P+++                   
Sbjct: 591 RSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPP 650

Query: 567 ----WIGKNSASWALCRCNNNWVVRHNSK----EIPIEPAPHLRRVGILLDYDNGSIAFY 618
                IG           +N  +   +       +P+ P     R+GI LDY+ G ++F 
Sbjct: 651 FAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPP-----RLGICLDYERGRVSFL 705

Query: 619 DALNSIHLYTFDVAFAQPVCPTF 641
           DA++   L    +  + PVCP F
Sbjct: 706 DAVSFRGLLECPLDCSGPVCPAF 728


>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score =  210 bits (535), Expect = 3e-54
 Identities = 146/493 (29%), Positives = 244/493 (49%), Gaps = 55/493 (11%)

Query: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276
           ++ ++ L   +  L  +N E+++ +  L Q   +VE N+++ +  L  E   L  ++++ 
Sbjct: 2   EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61

Query: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336
           ++ +  KIK+ +  R  +L  Q+A C + +E S  L+  A  +L+  D   F Q AK I 
Sbjct: 62  KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121

Query: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396
           + V+MA A    L  +  ++D      +DF++E+++L+ L +L  P+ P I       + 
Sbjct: 122 DGVTMAPAFRLSL--KAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179

Query: 397 DTITVHWTSDDEFSVVS-YELQY--TIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453
           + +T+ W   DE S +  Y L+Y  T F G   +         WM++  I+Q  YT+ GL
Sbjct: 180 NCVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRL----KEDQPWMVIEGIRQTEYTLTGL 235

Query: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511
           +   KY+ F VKA N+A     SEP  L+T +  F+LD  ++H+ L+V  D+L+VE D  
Sbjct: 236 KFDMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRV--DDLSVEWDAM 293

Query: 512 SSK-----------KSHTP-----------------------ERFTSQGSYGVAGNVFID 537
             K           K  T                        +RFT++ SY V G+  ID
Sbjct: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAE-SYTVLGDTLID 352

Query: 538 SGRHYWEVVIS-GSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV----VRHNSKE 592
            G HYWEV     S  + +G+AY+S  + E +GK +ASW  C   NNW+       ++ +
Sbjct: 353 GGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKTAASW--CLHVNNWLQVSFTAKHANK 410

Query: 593 IPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIIT 652
           + +  AP    +G+  D+  G ++FY+A     L+TF   F QP+ P FTVW     + T
Sbjct: 411 VKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTT 470

Query: 653 GLPIPDHLDCTEQ 665
           GL +P  + C ++
Sbjct: 471 GLQVPSAVRCLQK 483


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score =  193 bits (490), Expect = 5e-49
 Identities = 166/624 (26%), Positives = 262/624 (41%), Gaps = 71/624 (11%)

Query: 56  CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115
           CP C   + L  RGL G  +N  L+ +IDR+Q++                        A 
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164

Query: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174
            + CQ C++ P ++A   C  C+V YCD C    HP + P   HRL+ P      R L  
Sbjct: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223

Query: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229
                C +HE E  +MYCV     +C  C   G+H  H+V AL   +   K  L   L  
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283

Query: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289
           L  R  E +  L +L    Q ++ N+   EA L  +CD LI+ + +R+  +  ++ +   
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343

Query: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347
            +L+ +  QI++C   + ++  L+      +KEND + FLQ +  +  RV +        
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403

Query: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401
            L P +  +  FD  +LD S   + +  LD++        P  P ++ E C    ++ T+
Sbjct: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460

Query: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461
            W      +V +      +  G         +   +  V   K+   TV GL   + Y  
Sbjct: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511

Query: 462 MVKAINQAG-SRSSEPGKLKTNSQP-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTP 519
            VKA N+ G S  S+   L+T+    F  DP SAH  + +S+DNLTV             
Sbjct: 512 RVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV------------- 558

Query: 520 ERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWA 576
              +S     V G      G HYWE+ +     +   A G+A     K   +GK+  +WA
Sbjct: 559 -TCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWA 617

Query: 577 LCRCNN-NWVVRHNSKEIPIEPA-PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFA 634
           +   NN +W + +NS     E        +G+LLD +  ++ F+          FD    
Sbjct: 618 MYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEG 677

Query: 635 QPVCPTFTVWNKCLTIITGLPIPD 658
                     N  +T+ TGLP+PD
Sbjct: 678 LFFPAVSLNRNVQVTLHTGLPVPD 701


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score =  189 bits (480), Expect = 7e-48
 Identities = 158/620 (25%), Positives = 256/620 (41%), Gaps = 90/620 (14%)

Query: 50  SITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDAN 109
           S ++  CP C    +L  RGL G +RN  L+ I+ R+Q+   + P               
Sbjct: 153 SSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPG-------------- 198

Query: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
           T  +A   +CQ CD+ P + A   C  C+V YC  C    HP++ PF  HRL++P P   
Sbjct: 199 TSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPP 258

Query: 168 ------------------------------------SHIRGL-MCLEHEDEKVNMYCVTD 190
                                               S  R    C EHE E  +MYCV+ 
Sbjct: 259 PPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSC 318

Query: 191 DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQH 250
              +C LC   GRH  H+V  L   + + K  L   L  +  +  E +  L +L    Q 
Sbjct: 319 RTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQ 378

Query: 251 VEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSA 310
           ++ N    EA L  +CD L++ + +++  + TK+ + +  +L+ +  QI +C   + +S 
Sbjct: 379 IQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQST 438

Query: 311 SLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREK 370
            L+      +KEND + FLQ +  + +RV ++         E  ++  FD   LD     
Sbjct: 439 GLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLL 497

Query: 371 KLLECLDYL----TAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
           + +  LD++      P  P ++ E C    +++T+ W              +T       
Sbjct: 498 QAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMP----------PFTHSPVDGY 547

Query: 427 VVSLCNSADSWMIVPNI-KQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQ 484
           ++ L + A        + K+   T+ GL   + Y   VKA N +G    S+   L+T+  
Sbjct: 548 ILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDV 607

Query: 485 P-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYW 543
             F  DP S HR + +S+DN T                 +S     V G      G HYW
Sbjct: 608 AWFTFDPNSGHRDIILSNDNQTA--------------TCSSYDDRVVLGTAAFSKGVHYW 653

Query: 544 EVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWALCRCNN-NWVVRHNSKEIPIEPAP 599
           E+ +     +   A G+A  S  K   +GK+  +WA+   NN +W +  NS     E   
Sbjct: 654 ELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGV 713

Query: 600 -HLRRVGILLDYDNGSIAFY 618
                VG+LLD +  ++ F+
Sbjct: 714 CKGATVGVLLDLNKHTLTFF 733



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 18/36 (50%), Positives = 26/36 (72%)

Query: 4  LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILV 39
          +E EL CP+C  LF +P++LPC+H++C  CA  I V
Sbjct: 1  MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAV 36


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score =  152 bits (384), Expect = 1e-36
 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%)

Query: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63
           L  EL+C ICLE F++P+  PC H+ C +C +           +V+  + + CP CR V 
Sbjct: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57

Query: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123
               +    L +N  L N++++F +A ++    P++     A  A+  +   +V C  C 
Sbjct: 58  QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111

Query: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183
           ++    AVKTC+ C  S+C E L+  H +   F  H L  P+ D   R   C +H   + 
Sbjct: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164

Query: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
             +C    + IC +C +   H+    A+LS+    L+  L   LT +  +       L  
Sbjct: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222

Query: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303
           +    Q V + A+R+  +L +E   +  ++         KIKE +    +++  +     
Sbjct: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278

Query: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358
           Q + +  S    L  + E SL + D   FL+ A  +        ++  V IPE+ LN   
Sbjct: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333

Query: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410
                   +D   E K  +C+  L  P P +      +  +    T  V   S +E    
Sbjct: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391

Query: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466
               V +   +   F     +V L  +            +H     L++     F+ K  
Sbjct: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447

Query: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526
                  S P  L+   +   LD  +AH K+ +S         E        P+RFT   
Sbjct: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499

Query: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583
              V G      G HYWEV +  + +  +G+ Y S  +      +G+NSASW +   N  
Sbjct: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557

Query: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642
               HN+ E  + P+    RVG+LL+ D+G + F+   + +HL Y F V F + + P F 
Sbjct: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616

Query: 643 VWNKCLTI 650
           V++   T+
Sbjct: 617 VFSAGATL 624


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score =  149 bits (377), Expect = 6e-36
 Identities = 105/396 (26%), Positives = 181/396 (45%), Gaps = 79/396 (19%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVS---HCATNESVESITA--F 54
           ME LE +L CPICLE+F  P+ +LPC H+LC  CA+ I  +   +  +  S  S++   F
Sbjct: 14  MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRF 73

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CPTCRH + + + G+ GL+RN+ ++NIID ++                           
Sbjct: 74  RCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYK--------------------------- 106

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                Q C   P Q                  K +HP                      M
Sbjct: 107 -----QECSSRPLQ------------------KGSHP----------------------M 121

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
           C EHEDEK+N+YC+T +   C++CK+ G H+  +VA L   +   K  L + ++ L+  N
Sbjct: 122 CKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGN 181

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRK 294
             ++T++ +L  + +  + N+ + + +L+++ D L  I+ +++  +  +I + +  +L  
Sbjct: 182 DRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSF 241

Query: 295 LAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEIN 354
           +   I   ++ +++S  L+  A  SL E   A FL TAK + + +  A+   Q+   E  
Sbjct: 242 IEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQG 301

Query: 355 LNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREE 390
             +  D F LD       L  +D+ T        EE
Sbjct: 302 F-ENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEE 336


>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
          Length = 550

 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/429 (26%), Positives = 182/429 (42%), Gaps = 50/429 (11%)

Query: 56  CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115
           CP C   + L  RGL G  +N  L+ +IDR+Q++                        A 
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164

Query: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174
            + CQ C++ P ++A   C  C+V YCD C    HP + P   HRL+ P      R L  
Sbjct: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223

Query: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229
                C +HE E  +MYCV     +C  C   G+H  H+V AL   +   K  L   L  
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283

Query: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289
           L  R  E +  L +L    Q ++ N+   EA L  +CD LI+ + +R+  +  ++ +   
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343

Query: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347
            +L+ +  QI++C   + ++  L+      +KEND + FLQ +  +  RV +        
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403

Query: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401
            L P +  +  FD  +LD S   + +  LD++        P  P ++ E C    ++ T+
Sbjct: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460

Query: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461
            W      +V +      +  G         +   +  V   K+   TV GL   + Y  
Sbjct: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511

Query: 462 MVKAINQAG 470
            VKA N+ G
Sbjct: 512 RVKAFNKTG 520


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score =  126 bits (316), Expect = 7e-29
 Identities = 97/388 (25%), Positives = 180/388 (46%), Gaps = 44/388 (11%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSHCATNESVESITA-----F 54
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +     +S  S T      F
Sbjct: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S    + P  ++ E+          
Sbjct: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                  C++   +     C++CEV  C  C        K F  H+  E  P   I    
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
             +       + C   +   C+L   +    D  + A S+    +   L   +  L+  N
Sbjct: 171 KKQDLTLLPRLECSGTNTTYCSLD--LPSSSDPPILA-SQNTKIIDSELSDGIAMLVAGN 227

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRR----QIIGTKIKEGKVM 290
             ++ ++ ++ + CQ +E N+ RQ+  L +  + L  ++++R+    Q +  + +E K+ 
Sbjct: 228 DRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALARE-QEEKLQ 286

Query: 291 RLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLI 350
           R+R L +Q  +    +E S+ L+  A  S++E   A +LQ AK +  +V   +       
Sbjct: 287 RVRGLIRQYGD---HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGR 343

Query: 351 PEINLNDTFDTFALDFSREKKLLECLDY 378
           PE    ++ + F +      ++L  +D+
Sbjct: 344 PEPGY-ESMEQFTVRVEHVAEMLRTIDF 370


>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
           sapiens]
          Length = 749

 Score =  124 bits (310), Expect = 4e-28
 Identities = 85/290 (29%), Positives = 136/290 (46%), Gaps = 15/290 (5%)

Query: 378 YLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSW 437
           Y+TAP+PP I+ +   +  + + + W S +   V SY ++ T    QA         +S 
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELT----QAESPEASGVTESV 520

Query: 438 MIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQPFKLDPKSAHRK 496
           + +P  +    +V  LQ G  YI  V+A+N  G S  SEP  + T    F+L+  + H  
Sbjct: 521 VGIPTCE----SVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPW 576

Query: 497 LKVSHDNLTVERDESSSK-KSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAI 555
           L +S D LT  R E  +  +  +P          V GN+    G HYWEV +     Y +
Sbjct: 577 LTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRV 636

Query: 556 GLAYKSAPKHEWIGKNSASWAL----CRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYD 611
           G+A+    K E +G N  SW +        + +   HN     I      +++GILLDY+
Sbjct: 637 GVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYE 696

Query: 612 NGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNK-CLTIITGLPIPDHL 660
           +  ++F++   S HLYTF     + V P F++    CL +  G+ +P H+
Sbjct: 697 HSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 79/311 (25%), Positives = 142/311 (45%), Gaps = 11/311 (3%)

Query: 177 EHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTE 236
           E E+E  +++CVT    I A  K+   H++H+V  L+E  +  K  +  N+  L K+  E
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229

Query: 237 LETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLA 296
           +E     L +    VE N  +QE       + ++E + Q+ +     + E K  +L  L 
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289

Query: 297 QQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLN 356
            Q+ +C + ++    L+   E    E +   F++ A  + +R+     +   +  EI+  
Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346

Query: 357 DTFDTFALDFSREKKLLECLDYLTAPNPPTIREEL-CTASYDTITVHWTSDDEFSVVSYE 415
             F+   LDFS  ++L+  ++ + AP+ P I  ++  +A+  ++ V W+   + +V SY+
Sbjct: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406

Query: 416 LQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSS 474
           L Y        V       D       +K+ + +V  L   T+Y F V A N+AG S SS
Sbjct: 407 LSY------RPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSS 460

Query: 475 EPGKLKTNSQP 485
           E     T   P
Sbjct: 461 ERAVYMTAPSP 471


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score =  123 bits (308), Expect = 6e-28
 Identities = 94/388 (24%), Positives = 171/388 (44%), Gaps = 86/388 (22%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSHCATNESVESITA-----F 54
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA+ +  +     +S  S T      F
Sbjct: 17  MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S    + P  ++ E+          
Sbjct: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                  C++   +     C++CEV  C  C        K F  H               
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAH--------------- 155

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
                                         +D +VA L   Y + K  L   +  L+  N
Sbjct: 156 ------------------------------KDCEVAPLPTIYKRQKSELSDGIAMLVAGN 185

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRR----QIIGTKIKEGKVM 290
             ++ ++ ++ + CQ +E N+ RQ+  L +  + L  ++++R+    Q +  + +E K+ 
Sbjct: 186 DRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALARE-QEEKLQ 244

Query: 291 RLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLI 350
           R+R L +Q  +    +E S+ L+  A  S++E   A +LQ AK +  +V   +       
Sbjct: 245 RVRGLIRQYGD---HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGR 301

Query: 351 PEINLNDTFDTFALDFSREKKLLECLDY 378
           PE    ++ + F +      ++L  +D+
Sbjct: 302 PEPGY-ESMEQFTVRVEHVAEMLRTIDF 328


>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
          Length = 452

 Score =  122 bits (307), Expect = 8e-28
 Identities = 95/388 (24%), Positives = 176/388 (45%), Gaps = 88/388 (22%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSH-----CATNESVESITAF 54
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA  I  +           ++ S   F
Sbjct: 17  MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S         TR E+  D       
Sbjct: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES---------TRPEKKSDQ------ 121

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                  C++   +     C+ CEV  C  C        K F  H+  +  P +H+    
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
                                                    + + K  L   +  L+  N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRR----QIIGTKIKEGKVM 290
             ++ ++++L  TC+ +E    +Q+ +L E+ D L  I+++R+    Q+I T+ +E K+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVI-TRTQEEKLE 242

Query: 291 RLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLI 350
            +R L ++ ++    +E  + L+      + E + A FLQ AK + +++S A+ + Q+  
Sbjct: 243 HVRALIKKYSD---HLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEK 299

Query: 351 PEINLNDTFDTFALDFSREKKLLECLDY 378
            E    +  + F ++ +RE+K++  +D+
Sbjct: 300 IEHGY-ENMNHFTVNLNREEKIIREIDF 326


>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
          Length = 548

 Score =  122 bits (307), Expect = 8e-28
 Identities = 95/388 (24%), Positives = 176/388 (45%), Gaps = 88/388 (22%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSH-----CATNESVESITAF 54
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA  I  +           ++ S   F
Sbjct: 17  MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S         TR E+  D       
Sbjct: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES---------TRPEKKSDQ------ 121

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                  C++   +     C+ CEV  C  C        K F  H+  +  P +H+    
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
                                                    + + K  L   +  L+  N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRR----QIIGTKIKEGKVM 290
             ++ ++++L  TC+ +E    +Q+ +L E+ D L  I+++R+    Q+I T+ +E K+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVI-TRTQEEKLE 242

Query: 291 RLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLI 350
            +R L ++ ++    +E  + L+      + E + A FLQ AK + +++S A+ + Q+  
Sbjct: 243 HVRALIKKYSD---HLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEK 299

Query: 351 PEINLNDTFDTFALDFSREKKLLECLDY 378
            E    +  + F ++ +RE+K++  +D+
Sbjct: 300 IEHGY-ENMNHFTVNLNREEKIIREIDF 326


>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
          Length = 540

 Score =  122 bits (307), Expect = 8e-28
 Identities = 95/388 (24%), Positives = 176/388 (45%), Gaps = 88/388 (22%)

Query: 1   METLESELTCPICLELFEDPL-LLPCAHSLCFNCAHRILVSH-----CATNESVESITAF 54
           M+ LE +L CPICLE+F  P+ +LPC H+LC  CA  I  +           ++ S   F
Sbjct: 17  MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76

Query: 55  QCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSA 114
           +CP+CRH + L + G+ GL+RN+ ++NIID +++ S         TR E+  D       
Sbjct: 77  RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES---------TRPEKKSDQ------ 121

Query: 115 EKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM 174
                  C++   +     C+ CEV  C  C        K F  H+  +  P +H+    
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164

Query: 175 CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRN 234
                                                    + + K  L   +  L+  N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183

Query: 235 TELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRR----QIIGTKIKEGKVM 290
             ++ ++++L  TC+ +E    +Q+ +L E+ D L  I+++R+    Q+I T+ +E K+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVI-TRTQEEKLE 242

Query: 291 RLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLI 350
            +R L ++ ++    +E  + L+      + E + A FLQ AK + +++S A+ + Q+  
Sbjct: 243 HVRALIKKYSD---HLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEK 299

Query: 351 PEINLNDTFDTFALDFSREKKLLECLDY 378
            E    +  + F ++ +RE+K++  +D+
Sbjct: 300 IEHGY-ENMNHFTVNLNREEKIIREIDF 326


>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
          Length = 723

 Score =  103 bits (257), Expect = 5e-22
 Identities = 93/411 (22%), Positives = 170/411 (41%), Gaps = 37/411 (9%)

Query: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63
           L + L CP+C  L     +LPC HSLC  C  R L  H    E  E+     CP C    
Sbjct: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCL-RQLQKHA---EVTENFFILICPVCDRSH 195

Query: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123
            +       L  N     +  R+ +      +   + R +R        S+  +LCQ C 
Sbjct: 196 CMPYSNKMQLPENYLHGRLTKRYMQE-----HGYLKWRFDR--------SSGPILCQVCR 242

Query: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183
               + A K C+TC ++ C++CLKA H +      H  ++   +     + C+ H   ++
Sbjct: 243 N--RRIAYKRCITCRLNLCNDCLKAFHSDVA-MQDHVFVDTSAEEQDEKI-CIHHPSSRI 298

Query: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
             YC  D++L+C  CK    H  H   +L +   +   +L S +        E++  L +
Sbjct: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357

Query: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303
                   + +   +  ++      L  I+Q++ +II  +I+  +V R +++ + +    
Sbjct: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417

Query: 304 QCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFA 363
             +     LI+ ++ +LKE     FLQ+AK + +++     ++    P++ L+ + +   
Sbjct: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476

Query: 364 LDF------------SREKKLLECLDYLTAPNPPTIREELCTASYDTITVH 402
           LDF            +  KK+    D L +P P  +  E   A   T + H
Sbjct: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 10/73 (13%)

Query: 401 VHWTSDDEFSVVSYELQ-YTIFTGQANVVS--LCNSADSWMIVPNIKQNHYTVHGLQSGT 457
           V+WT   E  V S+E++ Y + T   N V   LC        + +I Q +  +H L   T
Sbjct: 621 VYWTCPAE-DVDSFEMEFYEVITSPPNNVQMELCGQ------IRDIMQQNLELHNLTPNT 673

Query: 458 KYIFMVKAINQAG 470
           +Y+F V+AIN  G
Sbjct: 674 EYVFKVRAINDNG 686


>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
          Length = 551

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 48/350 (13%)

Query: 5   ESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVIT 64
           E EL CPICL +F +P+ LPC H+ C  C     +      +S       +CP C     
Sbjct: 10  EEELICPICLHVFVEPVQLPCKHNFCRGC-----IGEAWAKDS----GLVRCPECNQAYN 60

Query: 65  LSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQ 124
                  GL++N+ L NI+++F    V  P +                    + C FC +
Sbjct: 61  QK----PGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCRR 97

Query: 125 DPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVN 184
            P   A K C+ CE   C   ++          GH L+E      +R   C +H   ++ 
Sbjct: 98  GPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL- 153

Query: 185 MYCVTDDQLICA-LCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243
            +C  +   +C   C   G H+ H V  +  R +++++ L      L +R  ++E  L K
Sbjct: 154 YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYK 213

Query: 244 LIQTCQHVE--VNASRQEAKLTEE--CDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQI 299
           L    + VE  VN  ++E +L  E    LL E ++Q  ++    + + +     + A Q 
Sbjct: 214 LESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEV----LDKAQAKFCSENAAQA 269

Query: 300 ANCKQCIERSASLISQAEHSLKENDHARFLQTAKNI---TERVSMATASS 346
            +  + ++ +  L+   +    + +   F++  K++    +R    T+SS
Sbjct: 270 LHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSS 319


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 34/255 (13%)

Query: 8   LTCPICLELF-----EDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHV 62
           L C +C ++F     + P LL C H++C +C  R+ +             A +CP  R V
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78

Query: 63  ITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFC 122
             L   G+ GLK+N  L  +++R Q   +    +  E+            S E ++   C
Sbjct: 79  TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESIIR--C 127

Query: 123 DQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEK 182
           D+D A  A   C  C    C EC + TH + K    HR + P+ D      MC +H+   
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185

Query: 183 VNMYCVTD----DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNT-EL 237
           +   C+ +      L+C +CK  G+H+ H+ + L    ++++ ++  ++ + I+  T E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244

Query: 238 ETLLAKLIQTCQHVE 252
                KL+   QH+E
Sbjct: 245 SDYSRKLVGIVQHIE 259


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 34/255 (13%)

Query: 8   LTCPICLELF-----EDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHV 62
           L C +C ++F     + P LL C H++C +C  R+ +             A +CP  R V
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78

Query: 63  ITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFC 122
             L   G+ GLK+N  L  +++R Q   +    +  E+            S E ++   C
Sbjct: 79  TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESIIR--C 127

Query: 123 DQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEK 182
           D+D A  A   C  C    C EC + TH + K    HR + P+ D      MC +H+   
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185

Query: 183 VNMYCVTD----DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNT-EL 237
           +   C+ +      L+C +CK  G+H+ H+ + L    ++++ ++  ++ + I+  T E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244

Query: 238 ETLLAKLIQTCQHVE 252
                KL+   QH+E
Sbjct: 245 SDYSRKLVGIVQHIE 259


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 34/255 (13%)

Query: 8   LTCPICLELF-----EDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHV 62
           L C +C ++F     + P LL C H++C +C  R+ +             A +CP  R V
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78

Query: 63  ITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFC 122
             L   G+ GLK+N  L  +++R Q   +    +  E+            S E ++   C
Sbjct: 79  TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESIIR--C 127

Query: 123 DQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEK 182
           D+D A  A   C  C    C EC + TH + K    HR + P+ D      MC +H+   
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185

Query: 183 VNMYCVTD----DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNT-EL 237
           +   C+ +      L+C +CK  G+H+ H+ + L    ++++ ++  ++ + I+  T E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244

Query: 238 ETLLAKLIQTCQHVE 252
                KL+   QH+E
Sbjct: 245 SDYSRKLVGIVQHIE 259


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 60/175 (34%), Positives = 90/175 (51%), Gaps = 8/175 (4%)

Query: 488 LDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVI 547
           LDP +AH  L +  D+ +V  ++S  K     ERF S     V G     SGRHYWEV +
Sbjct: 307 LDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPC--VLGRETFTSGRHYWEVEV 364

Query: 548 SGSTWYAIGLAYKSAPKHEW--IGKNSASWALCRCNNN-WVVRHNSKEIPIEPAPHLRRV 604
              T +AIG+  ++  K  +  +   +  WA+    N  W +      +P+   P  RRV
Sbjct: 365 GDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPP--RRV 422

Query: 605 GILLDYDNGSIAFYDALNSIHLYTF-DVAFAQPVCPTFTVWNKCLTIITGLPIPD 658
           GI LDY++G I+FY+  +   +YTF +V F+ P+ P F +W+     +T  PI D
Sbjct: 423 GIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCLWSSGKKPLTICPIAD 477


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 121/584 (20%), Positives = 216/584 (36%), Gaps = 124/584 (21%)

Query: 177  EHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSER--------------------- 215
            E +  +++ YC T    I A  K+ G H+DH+V+ L                        
Sbjct: 3503 ELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQEKSLR 3562

Query: 216  -----------YDKLKQNLESNLTNLIKRNTEL-ETLLAKLIQTCQHVEVNASRQEAKLT 263
                       ++ +++N   N   L ++N E+ + +LA+  +  Q  E    ++   L 
Sbjct: 3563 IEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKMEFLH 3622

Query: 264  EECDLLIEIIQQRRQIIGTKIKEGKVM-------RLRKLAQQIANCKQC---IERSASLI 313
            E+    ++ +   +  + T ++E + +          ++ +++ +  +    +E+  +  
Sbjct: 3623 EQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSAMESTASLEKMPAAF 3682

Query: 314  SQAEHSLKENDHARFLQTAKNIT---------ERVSMATASSQVLIPEINLNDTFDTFAL 364
            S  EH   ++  AR  Q  K +          +  + AT+++  +   +N  D  D+F +
Sbjct: 3683 SLFEHY--DDSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSMNKEDVIDSFQV 3740

Query: 365  DFSREKK---------------------LLECLD-------------------------Y 378
                E +                     + E L+                         +
Sbjct: 3741 YCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIF 3800

Query: 379  LTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWM 438
             TAP+ P IR E CT  ++T T+ W      +  +Y L+Y                +   
Sbjct: 3801 RTAPSTPVIRAEDCTVCWNTATIRWRPTTPEATETYTLEY--------CRQHSPEGEGLR 3852

Query: 439  IVPNIKQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQPFKLDPKSAHRKL 497
                IK     V+ LQ    Y F V+AIN  G S  SE   + T    F L  ++AH  L
Sbjct: 3853 SFSGIKGLQLKVN-LQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPAL 3911

Query: 498  KVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGL 557
             +S     +   E          R T   S  V G      G+HYWE  ++    Y +G+
Sbjct: 3912 HISSSGTVISFGER--------RRLTEIPS--VLGEELPSCGQHYWETTVTDCPAYRLGI 3961

Query: 558  AYKSAPKHEWIGKNSASWAL-CRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIA 616
               SA +   +G+   SW + C     +   ++     +       RVGILLDY+N  + 
Sbjct: 3962 CSSSAVQAGALGQGETSWYMHCSEPQRYTFFYSGIVSDVHVTERPARVGILLDYNNQRLI 4021

Query: 617  FYDALNSIHLYTFDVAFAQPVCPTFTVW--NKCLTIITGLPIPD 658
            F +A +   L+     F + V P F +    KC T+  G+  PD
Sbjct: 4022 FINAESEQLLFIIRHRFNEGVHPAFALEKPGKC-TLHLGIEPPD 4064


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 57/178 (32%), Positives = 88/178 (49%), Gaps = 6/178 (3%)

Query: 488 LDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVI 547
           LDP +A+  L VS D  +V+R E        PERF  +  Y V G     SGRHYWEV +
Sbjct: 344 LDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERF--EWRYCVLGCENFTSGRHYWEVEV 401

Query: 548 SGSTWYAIGLAYKSAPKHE-WIGKNSAS--WALCRCNNNWVVRHNSKEIPIEPAPHLRRV 604
                + IG+  K+  + + W+     +  W +   + N           ++     R+V
Sbjct: 402 GDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKV 461

Query: 605 GILLDYDNGSIAFYDALNSIHLYTF-DVAFAQPVCPTFTVWNKCLTIITGLPIPDHLD 661
           GI LDY+ G I+FY+A +  H+YTF   +F++P+ P F +     T +T  PIP  ++
Sbjct: 462 GIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIPKEVE 519


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 57/178 (32%), Positives = 88/178 (49%), Gaps = 6/178 (3%)

Query: 488 LDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVI 547
           LDP +A+  L VS D  +V+R E        PERF  +  Y V G     SGRHYWEV +
Sbjct: 302 LDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERF--EWRYCVLGCENFTSGRHYWEVEV 359

Query: 548 SGSTWYAIGLAYKSAPKHE-WIGKNSAS--WALCRCNNNWVVRHNSKEIPIEPAPHLRRV 604
                + IG+  K+  + + W+     +  W +   + N           ++     R+V
Sbjct: 360 GDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKV 419

Query: 605 GILLDYDNGSIAFYDALNSIHLYTF-DVAFAQPVCPTFTVWNKCLTIITGLPIPDHLD 661
           GI LDY+ G I+FY+A +  H+YTF   +F++P+ P F +     T +T  PIP  ++
Sbjct: 420 GIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIPKEVE 477


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,765,374
Number of Sequences: 37866
Number of extensions: 1127205
Number of successful extensions: 4628
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 3348
Number of HSP's gapped (non-prelim): 1155
length of query: 667
length of database: 18,247,518
effective HSP length: 109
effective length of query: 558
effective length of database: 14,120,124
effective search space: 7879029192
effective search space used: 7879029192
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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