Guide to the Human Genome
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Search of human proteins with 154426272

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154426272 hypothetical protein LOC54540 [Homo sapiens]
         (789 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154426272 hypothetical protein LOC54540 [Homo sapiens]            1644   0.0  
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]               278   2e-74
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    70   1e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    70   1e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    70   1e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    66   1e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     64   7e-10
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    61   5e-09
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    59   1e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                58   4e-08
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    57   5e-08
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         56   1e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     56   1e-07
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]          56   1e-07
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  55   3e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          55   3e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          55   3e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    54   4e-07
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    54   4e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          53   1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          53   1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          53   1e-06
gi|13128980 proline rich 14 [Homo sapiens]                             53   1e-06
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ...    53   1e-06
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       52   2e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    52   2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     52   2e-06
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...    52   3e-06
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    52   3e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    51   4e-06

>gi|154426272 hypothetical protein LOC54540 [Homo sapiens]
          Length = 789

 Score = 1644 bits (4258), Expect = 0.0
 Identities = 789/789 (100%), Positives = 789/789 (100%)

Query: 1   MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS 60
           MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS
Sbjct: 1   MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS 60

Query: 61  SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120
           SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF
Sbjct: 61  SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120

Query: 121 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC 180
           PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC
Sbjct: 121 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC 180

Query: 181 PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
           PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP
Sbjct: 181 PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240

Query: 241 LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC 300
           LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC
Sbjct: 241 LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC 300

Query: 301 DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD 360
           DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD
Sbjct: 301 DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD 360

Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420
           VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR
Sbjct: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420

Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480
           ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ
Sbjct: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480

Query: 481 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP 540
           SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP
Sbjct: 481 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP 540

Query: 541 PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK 600
           PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK
Sbjct: 541 PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK 600

Query: 601 PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS 660
           PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS
Sbjct: 601 PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS 660

Query: 661 RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR 720
           RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR
Sbjct: 661 RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR 720

Query: 721 SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL 780
           SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL
Sbjct: 721 SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL 780

Query: 781 KKTTPSTAQ 789
           KKTTPSTAQ
Sbjct: 781 KKTTPSTAQ 789


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score =  278 bits (710), Expect = 2e-74
 Identities = 246/745 (33%), Positives = 339/745 (45%), Gaps = 125/745 (16%)

Query: 60   SSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGS-------- 111
            S S    +++   C  N  D    +F+ A+K+    +S  SS +   +++ S        
Sbjct: 581  SDSKEKKNAAKKKCLYNFQD----AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVS 636

Query: 112  ---PPTIPGEAFPVS-EHHQHSDLTAPPNSPTGHHPQPASLIPS--HPSSFGSPPHPHLL 165
               PP++      +S E H+HS   AP NSPTG  P PA L P+   P++      PHL 
Sbjct: 637  SKRPPSVGDVFHGISKEDHRHSAPAAPRNSPTGLAPLPA-LSPAALSPAALSPASTPHLA 695

Query: 166  PTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCG 225
                A  FP           TA  TPG   +                 S C  P      
Sbjct: 696  -NLAAPSFPK----------TATTTPGFVDTRK---------------SFCPAPLPPATD 729

Query: 226  GHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERS 285
            G  S P          PS   DP C+GH+  +       PQ  + DE    +EDS SE S
Sbjct: 730  GSISAP----------PSVCSDPDCEGHRCENGVYD---PQQDDGDESA--DEDSCSEHS 774

Query: 286  SCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGG 345
            S TS+ST+Q++GK+CDCCYCEFFGH  PPAAPTSRNY E+REKLR RLT+RKEE P K  
Sbjct: 775  SSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMD 834

Query: 346  TLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALK 405
             +     E  VDHR V++LL+FINS+E K  +S RAAKRARHK +K E EKA+L AEA  
Sbjct: 835  QIS--ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE-EKARLEAEARA 891

Query: 406  QANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKN----TVKDSIRASFSVCE 461
            + +      + R   E   E  + E DR       RLQE++       K   R S    +
Sbjct: 892  REHLHLQEEQRRREEE---EDEEEEEDRFKEEF-QRLQELQKLRAVKKKKKERPSKDCPK 947

Query: 462  LSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPA 521
            L M +  F  + A E  P S    N S    ++P+ +         SP  H   +     
Sbjct: 948  LDMLTRNF--QAATESVPNSGNIHNGSLEQTEEPETSSH-------SPSRHMNHSE---- 994

Query: 522  PPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSS 581
                              P PG+  +      ++T          +  K   P       
Sbjct: 995  ------------------PRPGLGADGDAADPVDT----------RDSKFLLPKEVNGKQ 1026

Query: 582  KEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641
             E  S   ++ +    G   QK  RQ S+A    A     PP + E  S     A  +  
Sbjct: 1027 HEPLSFFFDIMQHHKEGNGKQK-LRQTSKASSEPARRPTEPPKATEGQSKPR--AQTESK 1083

Query: 642  GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQ 701
             +V++L  +            +          K EK   +     P E  +  + Q++ +
Sbjct: 1084 AKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPT-----PMEPTSPGEHQQNSK 1138

Query: 702  PPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPK--DMDGVEMDETDREVEYFKRF 759
                  PQ  P+GK + +  + K ++  +S+DDVFLPK  D+D V+MDET+REVEYFKRF
Sbjct: 1139 LVLAESPQ--PKGKNK-KNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRF 1195

Query: 760  CLDSAKQTRQKVAVNWTNFSLKKTT 784
            CLDSA+QTRQ++++NW+NFSLKK T
Sbjct: 1196 CLDSARQTRQRLSINWSNFSLKKAT 1220



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 48/169 (28%), Positives = 63/169 (37%), Gaps = 33/169 (19%)

Query: 53  DDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP 112
           D+S   SS+SSSSS +      G S    P     A K  G+  S   S     S   SP
Sbjct: 341 DESPQISSTSSSSSEADDEEADGESSGEPP----GAPKEDGVLGS--RSPRTEESKADSP 394

Query: 113 PTIPGEAFPVSEHHQHSDLTAPPNSPTGH--HPQPASLIPSHPSSFGSPP-HPHLLPTTP 169
           P     ++P  +  Q       PN+   H    + + L PS  ++   PP H  L P  P
Sbjct: 395 P----PSYPTQQAEQ------APNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPEKP 444

Query: 170 AAP----FPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFS 214
             P    +P      P+   T PH P P           P L   PPF+
Sbjct: 445 THPALHLYPHIHGHVPL--HTVPHLPRP--------LIHPTLYATPPFT 483



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%)

Query: 58  SSSSSSSSSSSSSSSCPGNSGDWDPSS---FLSAHKLSGLWNSPHSSGAMP-GSSLGSPP 113
           S  +  S + S   S P    +  P++    +   + SGL  S  ++GA+P G    SP 
Sbjct: 383 SPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPE 442

Query: 114 TIPGEAFPVSEH-HQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPA 170
                A  +  H H H  L   P     H P+P      HP+ + +PP  H     PA
Sbjct: 443 KPTHPALHLYPHIHGHVPLHTVP-----HLPRPLI----HPTLYATPPFTHSKALPPA 491


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%)

Query: 74  PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132
           PG    W     L+  +      SP  S A P GS+LG  P  P   FP S         
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303

Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181
            PP +P  T   P Q A   P          PS    PP  H+ P +   P  A   +CP
Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363

Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
               ATAP +P       Q+     T  P   +PPP                  P LPPP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406

Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296
           +  PLP       C   K AH   A     P  +   L  + +  S  ++ +S+    RD
Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463

Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340
               +    E             F  H   P  AP S+       K   RL  ++    L
Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518

Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400
           P K  T  G+P E ++    + E     + T P V    + +     +  + E E A+L+
Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575

Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460
           + A K+A    GS  P+P  E                                     +C
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601

Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517
           E   D +  SK  A    PQS   LP ++L   +   P I    +P     P     +A 
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656

Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575
             PA P     GP  P     GP   +   +G  +     T+P  +  +  +        
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716

Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630
            E+P+S+EV +     P      G P +  R  +Q A+ S A P    P   EVP     
Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771

Query: 631 ------------------AKGQVAGPKQPGRVLELP 648
                             A+G  AGP +P  V E P
Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%)

Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527
           S    A P P  L  PP   S +    P +     P TL SP   T      PAPP A +
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224

Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579
             P PP      P P         + P  G+ +  + V    R        P    +E  
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639
            S   P+ +  L  P S    P    R  S     EA  APR          K + A  K
Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333

Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699
            P R L LP       A +      P P   G  K             G+++++  E+  
Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388

Query: 700 VQPPGPARPQSLP 712
             PP P  P   P
Sbjct: 389 TPPPAPPLPPPAP 401



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%)

Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161
           G  L  PP  PG A      +SE    S L +PP+  T   P P  L P  P S   PP 
Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191

Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221
           P L   +P                  PHT            S P +  PP F   + P +
Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222

Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281
                  + P  PPP   P P     P   G +    G   +       +    E   +S
Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275

Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341
             RS      +           +   F    PP  P   +   ++E   ++   RKEE  
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330

Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401
            K      +P  P+   R   ++     + EP  P   +A   A  +L            
Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377

Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461
           ++  QA+  +G+  P P     L  P   L      L      +    K +   +     
Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428

Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514
                   S   A +P+P    P N + S+        Q   +  +L+    GS +    
Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560
               PG    P ++   +GP  P  E       +  PPG VPE  L    +      P+L
Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546

Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620
           +       P   Y   + P +  V   + EL   +SS  +         +AK S  S  P
Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591

Query: 621 RP 622
           +P
Sbjct: 592 KP 593



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%)

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566
           G PQ+ +    G P P       P PP      PPP + P    V    + P+      +
Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208

Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610
            TP    P +   +    P      P P +       G R                 G Q
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268

Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670
           A+ + ASP PR PA       KG   GP  P   L  P+             S P     
Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321

Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723
            +P+ E+   +K  S    P     RP  Q     + +P  P   ++      R  +S++
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381

Query: 724 KQEKPASS 731
           + ++ A +
Sbjct: 382 QADERAGT 389


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%)

Query: 74  PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132
           PG    W     L+  +      SP  S A P GS+LG  P  P   FP S         
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303

Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181
            PP +P  T   P Q A   P          PS    PP  H+ P +   P  A   +CP
Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363

Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
               ATAP +P       Q+     T  P   +PPP                  P LPPP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406

Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296
           +  PLP       C   K AH   A     P  +   L  + +  S  ++ +S+    RD
Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463

Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340
               +    E             F  H   P  AP S+       K   RL  ++    L
Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518

Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400
           P K  T  G+P E ++    + E     + T P V    + +     +  + E E A+L+
Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575

Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460
           + A K+A    GS  P+P  E                                     +C
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601

Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517
           E   D +  SK  A    PQS   LP ++L   +   P I    +P     P     +A 
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656

Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575
             PA P     GP  P     GP   +   +G  +     T+P  +  +  +        
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716

Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630
            E+P+S+EV +     P      G P +  R  +Q A+ S A P    P   EVP     
Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771

Query: 631 ------------------AKGQVAGPKQPGRVLELP 648
                             A+G  AGP +P  V E P
Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%)

Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527
           S    A P P  L  PP   S +    P +     P TL SP   T      PAPP A +
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224

Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579
             P PP      P P         + P  G+ +  + V    R        P    +E  
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639
            S   P+ +  L  P S    P    R  S     EA  APR          K + A  K
Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333

Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699
            P R L LP       A +      P P   G  K             G+++++  E+  
Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388

Query: 700 VQPPGPARPQSLP 712
             PP P  P   P
Sbjct: 389 TPPPAPPLPPPAP 401



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%)

Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161
           G  L  PP  PG A      +SE    S L +PP+  T   P P  L P  P S   PP 
Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191

Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221
           P L   +P                  PHT            S P +  PP F   + P +
Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222

Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281
                  + P  PPP   P P     P   G +    G   +       +    E   +S
Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275

Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341
             RS      +           +   F    PP  P   +   ++E   ++   RKEE  
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330

Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401
            K      +P  P+   R   ++     + EP  P   +A   A  +L            
Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377

Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461
           ++  QA+  +G+  P P     L  P   L      L      +    K +   +     
Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428

Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514
                   S   A +P+P    P N + S+        Q   +  +L+    GS +    
Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560
               PG    P ++   +GP  P  E       +  PPG VPE  L    +      P+L
Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546

Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620
           +       P   Y   + P +  V   + EL   +SS  +         +AK S  S  P
Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591

Query: 621 RP 622
           +P
Sbjct: 592 KP 593



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%)

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566
           G PQ+ +    G P P       P PP      PPP + P    V    + P+      +
Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208

Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610
            TP    P +   +    P      P P +       G R                 G Q
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268

Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670
           A+ + ASP PR PA       KG   GP  P   L  P+             S P     
Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321

Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723
            +P+ E+   +K  S    P     RP  Q     + +P  P   ++      R  +S++
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381

Query: 724 KQEKPASS 731
           + ++ A +
Sbjct: 382 QADERAGT 389


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%)

Query: 74  PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132
           PG    W     L+  +      SP  S A P GS+LG  P  P   FP S         
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303

Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181
            PP +P  T   P Q A   P          PS    PP  H+ P +   P  A   +CP
Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363

Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
               ATAP +P       Q+     T  P   +PPP                  P LPPP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406

Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296
           +  PLP       C   K AH   A     P  +   L  + +  S  ++ +S+    RD
Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463

Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340
               +    E             F  H   P  AP S+       K   RL  ++    L
Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518

Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400
           P K  T  G+P E ++    + E     + T P V    + +     +  + E E A+L+
Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575

Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460
           + A K+A    GS  P+P  E                                     +C
Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601

Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517
           E   D +  SK  A    PQS   LP ++L   +   P I    +P     P     +A 
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656

Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575
             PA P     GP  P     GP   +   +G  +     T+P  +  +  +        
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716

Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630
            E+P+S+EV +     P      G P +  R  +Q A+ S A P    P   EVP     
Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771

Query: 631 ------------------AKGQVAGPKQPGRVLELP 648
                             A+G  AGP +P  V E P
Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%)

Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527
           S    A P P  L  PP   S +    P +     P TL SP   T      PAPP A +
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224

Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579
             P PP      P P         + P  G+ +  + V    R        P    +E  
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639
            S   P+ +  L  P S    P    R  S     EA  APR          K + A  K
Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333

Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699
            P R L LP       A +      P P   G  K             G+++++  E+  
Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388

Query: 700 VQPPGPARPQSLP 712
             PP P  P   P
Sbjct: 389 TPPPAPPLPPPAP 401



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%)

Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161
           G  L  PP  PG A      +SE    S L +PP+  T   P P  L P  P S   PP 
Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191

Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221
           P L   +P                  PHT            S P +  PP F   + P +
Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222

Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281
                  + P  PPP   P P     P   G +    G   +       +    E   +S
Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275

Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341
             RS      +           +   F    PP  P   +   ++E   ++   RKEE  
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330

Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401
            K      +P  P+   R   ++     + EP  P   +A   A  +L            
Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377

Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461
           ++  QA+  +G+  P P     L  P   L      L      +    K +   +     
Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428

Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514
                   S   A +P+P    P N + S+        Q   +  +L+    GS +    
Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560
               PG    P ++   +GP  P  E       +  PPG VPE  L    +      P+L
Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546

Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620
           +       P   Y   + P +  V   + EL   +SS  +         +AK S  S  P
Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591

Query: 621 RP 622
           +P
Sbjct: 592 KP 593



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%)

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566
           G PQ+ +    G P P       P PP      PPP + P    V    + P+      +
Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208

Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610
            TP    P +   +    P      P P +       G R                 G Q
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268

Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670
           A+ + ASP PR PA       KG   GP  P   L  P+             S P     
Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321

Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723
            +P+ E+   +K  S    P     RP  Q     + +P  P   ++      R  +S++
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381

Query: 724 KQEKPASS 731
           + ++ A +
Sbjct: 382 QADERAGT 389


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 166/728 (22%), Positives = 231/728 (31%), Gaps = 92/728 (12%)

Query: 82   PSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGH 141
            P   L+     G   +P ++   P   L +PP       P +         A P SP G 
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-SPKGA 1194

Query: 142  HPQPASLIPSH------PSSFGSPPHPHLLPTTP----AAPFPAQASECPVAAATAPH-- 189
               PA+  PS       PS  G+P  P   P +P    A P P  A   P A   +P   
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254

Query: 190  --TPGPCQSSHLPSTSMPLLK---MPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPST 244
              TP P  +   P+ + P LK     PP  G  +P          GP   PP   P P  
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314

Query: 245  HRDPGCKGH------KFAHSGLACQLPQ-------PCEADEGLGEEEDSSSERSSCTSSS 291
               P  KG       K A +  A   P        P       G     SS+      ++
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 292  THQRDGKFCDCCYCEFFGH--NAPPAAPTSRNYTEIREKL--RSRLTRRKEELPMKGG-- 345
            T    G           G    +P   PTS     +  K    + +TR     P KG   
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434

Query: 346  -------TLGGIP------GEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKK 392
                   +L   P      G PA      D  L  +    PK P + +    +    KK 
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP-KKA 1493

Query: 393  EKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDS 452
                A + A  L      S    P     R      R+     + L S+        K++
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSR------RDPIAPTATLLSKKTPATLAPKEA 1547

Query: 453  IRASFSVCELSMDSNGFSKEGAAEPEPQS----LPPSNLSGSSEQQPDINLDLSPLTLGS 508
            +            +        A   P S     PP+    + +  P     L P  + S
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607

Query: 509  PQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT 568
            P       P    PP  E +GP  P  +     P + P +     L   P     +  K 
Sbjct: 1608 PSPKEAPTPPAVTPPSPE-KGPATPAPKGTPTSPPVTPSS-----LKDSPTSPASVTCKM 1661

Query: 569  PKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKP--QKGKRQGSQAKKSEASPAPRPPASL 626
                  +S+   +K+ P+  +E+    +    P      R+G Q KKS A+  P  P   
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD-- 1719

Query: 627  EVPSAKGQVAGPKQ---PGRVLELPKVGSCAEAGEGSRGSRPGP-----GWAGSPKT--- 675
              PSAK    GP     P  +L + K  S    G+ +  S  GP       A +P T   
Sbjct: 1720 --PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777

Query: 676  -----EKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730
                  K + +S    P    + P     V P  P + Q LP   G    S +K   PA 
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPV-PTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836

Query: 731  SLDDVFLP 738
              +D  LP
Sbjct: 1837 --EDELLP 1842



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 60/232 (25%), Positives = 77/232 (33%), Gaps = 43/232 (18%)

Query: 61   SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120
            +++  S     + P   G   P +        GL   PH     P +   +PP+  G   
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA--PTTPAATPPSPKG--- 1138

Query: 121  PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA--------- 171
                      L  PP  P G    PA+  PS      +PP P   PTTPAA         
Sbjct: 1139 ---------GLATPP--PKGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGL 1186

Query: 172  --PFPAQASECPVAAATAPH----TPGPCQSSHLPSTSMPL----LKMPPPFSGCSHPCS 221
              P P  A   P A   +P     TP P  +   P+ + P     L  P P    + P +
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 222  GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKG------HKFAHSGLACQLPQP 267
                    GP  PPP   P P     P  KG      HK A +      P P
Sbjct: 1247 TPPSPK-GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/180 (27%), Positives = 59/180 (32%), Gaps = 27/180 (15%)

Query: 97   SPHSSGAMPGSSLGSPPTIPGEAFP----VSEHHQHSDLTAPPNSPTGHHPQPASLIPSH 152
            +P    A P S  G P T   +  P    V+         A P  P G    PA+  PS 
Sbjct: 985  APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP-FPKGASTPPAATPPSP 1043

Query: 153  PSSFGSPPHPHLLPTTPAAPFPA--------QASECPVAAATAPHTP--GPCQSSHLPST 202
              S  + P P   PTTPAA  P+             P   A  P +P  GP   S   + 
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103

Query: 203  SMPLLKMPPPFSGCSHPCSGHCGGHCS----------GPLLPPPSSQPLPSTHRDPGCKG 252
              P    P P  G + P   H G   +          G   PPP   P       P  KG
Sbjct: 1104 MPPAATPPSPKGGLATP--PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 59/234 (25%), Positives = 79/234 (33%), Gaps = 34/234 (14%)

Query: 41  LSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHS 100
           +SHTS  +          +  S +S+++SS        D  PS  L           P  
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD-SPSP-LGVSVSPQTKRPPTK 811

Query: 101 SG-AMPGSSLG--SPPTIPGEAFPVSEH----HQHSDLTAPPNSPTGHHPQ----PASLI 149
            G A P + +G  S P  P EA  + E+        D  A  +SPT   P+    P+++ 
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871

Query: 150 PSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLK- 208
           P  P     PP     P+    PFP +           P TP P Q+  L  TS    K 
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKE----------GPATPAPKQAPALSMTSSSPKKA 921

Query: 209 ----------MPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKG 252
                       P   G   P +        GP  P P   P P     P  KG
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/267 (26%), Positives = 93/267 (34%), Gaps = 43/267 (16%)

Query: 472  EGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPL-TLGSPQNH--TLQAPGEPAPPWAE-- 526
            +GA+ P P + PPS     +          +P  TL SP+    T    G P PP A   
Sbjct: 1030 KGASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 527  --MRGPHPPWTEVRGPPPGIVP---ENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSS 581
                GP  P  +    PP   P   + GL    +     +      +PK G  +   P  
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT---PPP 1145

Query: 582  KEVPSCKQELPEPVSSGG---KPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGP 638
            K  P+     P P   GG    P KG      A  + A+  P P   L  PS KG    P
Sbjct: 1146 KGAPTTPAATP-PSPKGGLATPPPKG------APTTPAATPPSPKGGLATPSPKG---AP 1195

Query: 639  KQPGRVLELPKVGSCAEAGEGS-----------RGSRPGPGWAGSPKTEKEKGSSWRNWP 687
              P      PK G    + +G+           +G    P   G+P T      S +  P
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255

Query: 688  GEAKARPQEQESVQPPGPARPQSLPQG 714
                A P  + +  PP  A P SL  G
Sbjct: 1256 ----ATPPPKGAPTPPA-ATPPSLKGG 1277



 Score = 36.6 bits (83), Expect = 0.093
 Identities = 49/176 (27%), Positives = 65/176 (36%), Gaps = 21/176 (11%)

Query: 106  GSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSH--PSSFGSP--PH 161
            G +  +P   P  +   S   +     AP   P    P+ A   P+   PS  G P  P 
Sbjct: 899  GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958

Query: 162  PHLLPTTPAAPFPA----QASECPVAAATAP-HTP-----GPCQSSHLPSTSMPLLKMPP 211
            P   PT PAA  P+     A+  P  A T P  TP     GP   S   + + P +  P 
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018

Query: 212  PFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQP 267
            P    S   +    G  + P   PPS +  P+    P     K A +  A  LP P
Sbjct: 1019 PKG--SPAATPFPKGASTPPAATPPSPKGSPAATPLP-----KGAPTTPAATLPSP 1067



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 56/255 (21%), Positives = 86/255 (33%), Gaps = 37/255 (14%)

Query: 464  MDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPP 523
            +  N  S +G+ +    +  P+  S      P      S +T  SP+  TL     P P 
Sbjct: 836  LPENSLSFQGSKDSPATTHSPTPPSPKGAPTP------SAVTPLSPKGVTLPPKETPTPS 889

Query: 524  WAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKP-GYPSSEEPSSK 582
               +  P        GP      +   +   ++ P  +R     TP P G P+S  P   
Sbjct: 890  VVNLPFPK------EGPATPAPKQAPALSMTSSSPKKARA----TPAPKGIPASPSPKGA 939

Query: 583  EVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPG 642
              P        P ++   P+ G    S  K +   PA  PP+    P+       P  P 
Sbjct: 940  PTP--------PAATPPSPKGGPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990

Query: 643  RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP 702
                 PK G    + +G+    P P     P  +    ++   +P  A   P    +  P
Sbjct: 991  ATPPSPKGGPATPSPKGA----PTPPAVTPPSPKGSPAAT--PFPKGASTPP----AATP 1040

Query: 703  PGP-ARPQSLPQGKG 716
            P P   P + P  KG
Sbjct: 1041 PSPKGSPAATPLPKG 1055



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 24/96 (25%)

Query: 98  PHSSGAMPGSSLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSF 156
           P SS     ++LG P PT+P                 PP SP    PQ   L  ++ +S 
Sbjct: 27  PMSSALSVTAALGQPGPTLP-----------------PPCSPA---PQQCPLSAANQAS- 65

Query: 157 GSPPHPHLLPTTPA-APFPAQASECPVAAATAPHTP 191
              P P  + +TP   PFP  +S   +   TAP  P
Sbjct: 66  -PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP 100


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 80/300 (26%), Positives = 106/300 (35%), Gaps = 58/300 (19%)

Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPP 523
           G   +G   P +PQ  PP      S + P           G PQ    Q    P  P PP
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----------GKPQGPPPQGGNQPQGPPPP 135

Query: 524 WAEMRGPHPPW-TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSK 582
             + +GP P    + +GPPP   P+ G   + +     SR    K   P      +P   
Sbjct: 136 PGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194

Query: 583 EVPSCKQELPEPVSSG--------GKPQKGKRQGSQAKKSEASPA--------------- 619
             P  K + P P            GKPQ    QG    +S  SP                
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254

Query: 620 --PRPPASLEVPSAKG--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKT 675
             P PP   + P  +G  +  GP  PG+    P  G     G  SR SR  PG    P+ 
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-----GSKSRSSRSPPG---KPQG 306

Query: 676 EKEKGSSWRNWPGEAKARPQE------QESVQPPGPARPQS-LPQGKGRSRRSRNKQEKP 728
              +G +    P     +PQ        +   PP P +PQ   PQG  +SR +R+   KP
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 72/254 (28%), Positives = 87/254 (34%), Gaps = 42/254 (16%)

Query: 479 PQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPPWAEMRGPHPPW- 534
           PQ  PP    G+  Q P       P   G PQ    Q    P  P PP  + +GP P   
Sbjct: 36  PQGAPPQG--GNKPQGP-------PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86

Query: 535 TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQ 589
            + +GPPP     G  P+    R   + P        K   P      +P     P  K 
Sbjct: 87  NKPQGPPPPGKPQGPPPQGDKSRSPRSPPG-------KPQGPPPQGGNQPQGPPPPPGKP 139

Query: 590 ELPEPVSSG--------GKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641
           + P P            GKPQ    QG    +S  SP  +P      P    Q  GP  P
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP--PPQGGNQPQGPPPP 197

Query: 642 -GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV 700
            G+    P  G     G    G   GP     P     K  S R+ PG+ +  P  Q   
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGP-----PPQGDNKSQSARSPPGKPQG-PPPQGGN 251

Query: 701 QPPGPARPQSLPQG 714
           QP GP  P   PQG
Sbjct: 252 QPQGPPPPPGKPQG 265



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 71/273 (26%), Positives = 97/273 (35%), Gaps = 39/273 (14%)

Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPPWAEMRGPHPPW 534
           +PQ  PP         Q D     S    G PQ    Q    P  P PP  + +GP P  
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208

Query: 535 -TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPE 593
             + +GPPP   P+ G   + +     +R    K   P      +P     P  K + P 
Sbjct: 209 GNKPQGPPPPGKPQ-GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267

Query: 594 PVSSG--------GKPQKGKRQGSQAKKSEASPA-----------------PRPPASLEV 628
           P            GKPQ    QG    +S  SP                  P PP   + 
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327

Query: 629 PSAKG--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNW 686
           P  +G  +  GP  PG+    P  G     G  SR +R  PG    P   +++G++ +  
Sbjct: 328 PPPQGGNKPQGPPPPGKPQGPPPQG-----GSKSRSARSPPGKPQGPP--QQEGNNPQGP 380

Query: 687 PGEAKARPQEQESVQPPGPARPQSLPQGKGRSR 719
           P  A   PQ+ ++     P  P   PQG   SR
Sbjct: 381 PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 49/170 (28%), Positives = 65/170 (38%), Gaps = 26/170 (15%)

Query: 576 SEEPSSKEVPSCKQELPE--PVSSGGKPQ-----KGKRQGSQAKKSEASPAPRPPASLEV 628
           +E+ S +E PS     P+  P   G KPQ      GK QG   +       P PP     
Sbjct: 20  NEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 79

Query: 629 ---PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRN 685
              P    +  GP  PG+    P        G+ SR  R  PG    P+    +G +   
Sbjct: 80  GPPPQGGNKPQGPPPPGKPQGPPP------QGDKSRSPRSPPG---KPQGPPPQGGNQPQ 130

Query: 686 WPGEAKARPQE------QESVQPPGPARPQSLP-QGKGRSRRSRNKQEKP 728
            P     +PQ        +   PP P +PQ  P QG  +SR SR+   KP
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP 180



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 34/163 (20%)

Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAE 526
           G   +G   P +PQ  PP   S S   +        P   G  Q      P  P PP  +
Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ------PQGPPPPPGK 324

Query: 527 MRGPHPPW-TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPS 580
            +GP P    + +GPPP     G  P+ G   R    P           KP  P  +E +
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP---------PGKPQGPPQQEGN 375

Query: 581 SKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPP 623
           + + P        P  +GG PQ    Q       +    PRPP
Sbjct: 376 NPQGP--------PPPAGGNPQ----QPQAPPAGQPQGPPRPP 406



 Score = 33.5 bits (75), Expect = 0.79
 Identities = 46/178 (25%), Positives = 55/178 (30%), Gaps = 26/178 (14%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPG--EAFPVSEHHQHSDLTAPPNSPTGHHP- 143
           N P      PG   G PP           PG  +  P    ++     +PP  P G  P 
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186

Query: 144 ---QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GP 193
              QP    P      G PP     P  P  P      P Q      +A + P  P   P
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246

Query: 194 CQSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249
            Q  + P    P    P  PP  G + P      G   GP  PP       S+   PG
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSSRSPPG 302



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 38/145 (26%), Positives = 45/145 (31%), Gaps = 21/145 (14%)

Query: 98  PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFG 157
           P   G     S  SPP  P +  P    +Q      PP  P G  PQ  +  P  P   G
Sbjct: 286 PPPQGGSKSRSSRSPPGKP-QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPG 343

Query: 158 SPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTSMPLLKMPPPFSG 215
            P  P           P Q      +A + P  P   P Q  + P         PPP  G
Sbjct: 344 KPQGP-----------PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP------PPPAGG 386

Query: 216 CSHPCSGHCGGHCSGPLLPPPSSQP 240
                     G   GP  PP   +P
Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQGGRP 411



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 45/178 (25%), Positives = 54/178 (30%), Gaps = 26/178 (14%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPG--EAFPVSEHHQHSDLTAPPNSPTGHHP- 143
           N P      PG   G PP           PG  +  P    ++     +PP  P G  P 
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248

Query: 144 ---QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GP 193
              QP    P      G PP     P  P  P      P Q      ++ + P  P   P
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308

Query: 194 CQSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249
            Q  + P    P    P  PP  G + P      G   GP  PP       S    PG
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSARSPPG 364



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 45/177 (25%), Positives = 54/177 (30%), Gaps = 25/177 (14%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143
           N P      PG   G PP           PG+   P  +  +     +PP  P G  P  
Sbjct: 66  NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125

Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GPC 194
             QP    P      G PP     P  P  P      P Q      ++ + P  P   P 
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185

Query: 195 QSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249
           Q  + P    P    P  PP  G + P      G   GP  PP       S    PG
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDNKSQSARSPPG 240



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 41/166 (24%), Positives = 53/166 (31%), Gaps = 18/166 (10%)

Query: 87  SAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHP--- 143
           SA  L+   +   S   + G+  G+PP            ++     +PP  P G  P   
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGAPP---------QGGNKPQGPPSPPGKPQGPPPQGG 65

Query: 144 -QPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLPS 201
            QP    P      G PP     P  P  P   Q        + +P + PG  Q      
Sbjct: 66  NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125

Query: 202 TSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRD 247
            + P    PPP      P  G  G    GP  PPP     P    D
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQG--GNKPQGP--PPPGKPQGPPPQGD 167



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 37/145 (25%), Positives = 46/145 (31%), Gaps = 42/145 (28%)

Query: 586 SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGR 643
           S  Q L E VS    P    G  QG+  +       P        PS  G+  GP   G 
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGP--------PSPPGKPQGPPPQG- 64

Query: 644 VLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPP 703
                        G   +G  P PG    P             P +   +PQ      PP
Sbjct: 65  -------------GNQPQGPPPPPGKPQGP-------------PPQGGNKPQG-----PP 93

Query: 704 GPARPQSLPQGKGRSRRSRNKQEKP 728
            P +PQ  P    +SR  R+   KP
Sbjct: 94  PPGKPQGPPPQGDKSRSPRSPPGKP 118


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 72/281 (25%), Positives = 102/281 (36%), Gaps = 57/281 (20%)

Query: 468 GFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---------PG 518
           G S +G  +P+    PP    G   Q    N    P   G PQ    Q          PG
Sbjct: 38  GPSPQGGNKPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95

Query: 519 EPAPP----WAEMRGPHPPWTEVRGPPP--GIVPENGLVRRLNTVPNLSRVIWVKTPKPG 572
           +P  P      + +GP PP  + +GPPP  G  P+                     P PG
Sbjct: 96  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG-------------------PPPPG 136

Query: 573 YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAK 632
            P    P   +  S       P S  GKPQ    QG     ++    P PP   + P  +
Sbjct: 137 KPQGPPPQGDKSRS-------PRSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQ 185

Query: 633 G--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690
           G  +  GP  PG+    P  G  + + +   G   GP   G  + +          PG+ 
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP-----PGKP 240

Query: 691 KARPQE--QESVQPPGPARPQSLP-QGKGRSRRSRNKQEKP 728
           +  P +   +   PP P +PQ  P QG  +S+ +R+   KP
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 70/264 (26%), Positives = 98/264 (37%), Gaps = 53/264 (20%)

Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPA--PPWAEMRGPHPPWT 535
           +PQ  PP    G+  Q P       P   G PQ    Q    P   PP  + +GP P   
Sbjct: 96  KPQGPPPQG--GNQPQGP-------PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146

Query: 536 EVRGP--PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPE 593
           + R P  PPG        +     P          P PG P    P   + P   Q  P 
Sbjct: 147 KSRSPRSPPG--------KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP---QGPPP 195

Query: 594 PVSSGGKPQKGKRQGSQAKKSEASPA----------------PRPPASLEVPSAKG--QV 635
           P    GKPQ    QG +++ S++ P                 P PP   + P  +G  + 
Sbjct: 196 P----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251

Query: 636 AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695
            GP  PG+       G  A+ G  S+ +R  PG    P   +++G++ +  P  A   PQ
Sbjct: 252 QGPPPPGK-----PQGPPAQGGSKSQSARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQ 304

Query: 696 EQESVQPPGPARPQSLPQGKGRSR 719
           + ++     P  P   PQG   SR
Sbjct: 305 QPQAPPAGQPQGPPRPPQGGRPSR 328



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 72/259 (27%), Positives = 94/259 (36%), Gaps = 43/259 (16%)

Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPP 523
           G   +G   P +PQ  PP      S + P           G PQ    Q    P  P PP
Sbjct: 65  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----------GKPQGPPPQGGNQPQGPPPP 114

Query: 524 WAEMRGPHPPW-TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSE 577
             + +GP P      +GPPP     G  P+    R   + P        K   P      
Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPG-------KPQGPPPQGGN 167

Query: 578 EPSSKEVPSCKQELPEPVSSGGK-----PQKGKRQGSQAKKSEASPAPRPPASLEVPSAK 632
           +P     P  K + P P   GGK     P  GK QG   +  ++  +  PP   + P  +
Sbjct: 168 QPQGPPPPPGKPQGPPP--QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225

Query: 633 G--QVAGPKQP-GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGE 689
           G  Q  GP  P G+    P  G     G    G   GP   G  K++     S R+ PG+
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ-----SARSPPGK 280

Query: 690 AKARPQEQESVQPPGPARP 708
            +  PQ QE   P GP  P
Sbjct: 281 PQGPPQ-QEGNNPQGPPPP 298



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 43/166 (25%), Positives = 51/166 (30%), Gaps = 27/166 (16%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143
           N P      PG   G PP           PG+   P  +  +     +PP  P G  P  
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226

Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GPC 194
             QP    P      G PP     P  P  P      PAQ      +A + P  P   P 
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286

Query: 195 QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
           Q  + P         PPP  G          G   GP  PP   +P
Sbjct: 287 QEGNNPQGP------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 43/167 (25%), Positives = 51/167 (30%), Gaps = 19/167 (11%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143
           N P      PG   G PP           PG+   P  +  +     +PP  P G  P  
Sbjct: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104

Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLP 200
             QP    P      G PP     P  P  P   Q        + +P + PG  Q     
Sbjct: 105 GNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 164

Query: 201 STSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRD 247
             + P    PPP      P  G  G    GP  PPP     P    D
Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQG--GKKPQGP--PPPGKPQGPPPQGD 207


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 62/239 (25%)

Query: 487 LSGSSEQQPDINLDLSP-LTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPP--G 543
           LS +     D++ + SP L  G+PQ  + Q   +P       +GP PP  + +GPPP  G
Sbjct: 13  LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKP-------QGPPPPPGKPQGPPPQGG 65

Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQK 603
             P+                     P PG P    P   +  S +    +P   G  PQ 
Sbjct: 66  NKPQG-------------------PPPPGKPQGPPPQGDKSRSPRSPPGKP--QGPPPQG 104

Query: 604 GKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGS 663
           GK QG             PP     P    +  GP  PG+       G  A+ G  S+ +
Sbjct: 105 GKPQG-------------PP-----PQGGNKPQGPPPPGK-----PQGPPAQGGSKSQSA 141

Query: 664 RPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV---QPPGPARPQSLPQGKGRSR 719
           R  PG    P   +++G++ +  P  A   PQ+ ++    QP GP RP   PQG   SR
Sbjct: 142 RSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP---PQGGRPSR 195



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 41/157 (26%), Positives = 50/157 (31%), Gaps = 20/157 (12%)

Query: 96  NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHPQP 145
           N P      PG   G PP           PG+   P  +  +     +PP  P G  PQ 
Sbjct: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104

Query: 146 ASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTS 203
                  P   G+ P     P  P  P PAQ      +A + P  P   P Q  + P   
Sbjct: 105 GKP-QGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 162

Query: 204 MPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
                 PPP  G          G   GP  PP   +P
Sbjct: 163 ------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 193



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 39/157 (24%), Positives = 52/157 (33%), Gaps = 34/157 (21%)

Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAE 526
           G   +G   P +PQ  PP      S + P       P   G PQ    Q   +P      
Sbjct: 65  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKP------ 118

Query: 527 MRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPS 586
            +GP PP     G P G   + G   +    P           KP  P  +E ++ + P 
Sbjct: 119 -QGPPPP-----GKPQGPPAQGGSKSQSARSP---------PGKPQGPPQQEGNNPQGP- 162

Query: 587 CKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPP 623
                  P  +GG PQ    Q       +    PRPP
Sbjct: 163 -------PPPAGGNPQ----QPQAPPAGQPQGPPRPP 188


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 27/233 (11%)

Query: 484 PSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPG 543
           P  + GS  QQ  +  +        P+ H     G P PP A  RGP  P  E R  PPG
Sbjct: 642 PPGVPGSVVQQEGLKGEQGA---PGPRGHQ----GAPGPPGA--RGPIGP--EGRDGPPG 690

Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQK 603
           +    G    +   P +  ++ ++ P PG P    P     P     LP  +   GKP  
Sbjct: 691 LQGLRGKKGDMGP-PGIPGLLGLQGP-PGPPGVPGPPG---PGGSPGLPGEIGFPGKPGP 745

Query: 604 GKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGS 663
               G   K     P P PP +   P  +G+   P +PG   E+ + G     GE     
Sbjct: 746 PGPTGPPGKDGPNGP-PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804

Query: 664 RPG----PGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLP 712
            PG    PG  G    + EKG      PG    R ++ E+    GPA P  LP
Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGE--LGLPGLKGDRGEKGEA----GPAGPPGLP 851



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 74/258 (28%), Positives = 90/258 (34%), Gaps = 32/258 (12%)

Query: 471  KEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGP 530
            KEG   P PQ   PS L G   ++     D  P   G P       PG P P  A  RGP
Sbjct: 1223 KEGP--PGPQG--PSGLPGIPGEEGKEGRDGKPGPPGEPGK--AGEPGLPGPEGA--RGP 1274

Query: 531  HPPWTEVRGPP--PGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCK 588
             P +    G    PG   E+G +     +P    +   K    G    + P     P  K
Sbjct: 1275 -PGFKGHTGDSGAPGPRGESGAMG----LPGQEGLPG-KDGDTGPTGPQGPQGPRGPPGK 1328

Query: 589  QELP----EPVSSGGKPQKGKR--QGSQAKKSEASPA--PRPPASLEVPSAKGQVAGPKQ 640
               P    EP  SG   QKG +   GS        P   P  P    VP  +G    P +
Sbjct: 1329 NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388

Query: 641  PGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV 700
            PG   E    G      +G +G   G G  G P     KG +    P   +  P E   V
Sbjct: 1389 PGFKGERGDPGI-----KGDKGPPGGKGQPGDPGIPGHKGHTGLMGP---QGLPGENGPV 1440

Query: 701  QPPGPARPQSLPQGKGRS 718
             PPGP      P  +G S
Sbjct: 1441 GPPGPPGQPGFPGLRGES 1458



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 60/255 (23%), Positives = 86/255 (33%), Gaps = 42/255 (16%)

Query: 517  PGEPAPPWAEMRGPHPPWTEVRGP--PPGIVPENGLVRRLNTVPNLSRVIWVKTPKP--- 571
            PG P  P  + R   P     +GP  PPG   + G         N      V  P P   
Sbjct: 876  PGLPGEPGLQGR---PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 932

Query: 572  ----------GYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASP--- 618
                      G P  +    ++  + ++  P PV   G P      G   K  +  P   
Sbjct: 933  PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 992

Query: 619  -APRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEK 677
             +P  P  L   +A G+V G +            +CA  G+  +G R  PG  GSP +  
Sbjct: 993  GSPGLPGPLGTKAACGKVRGSE------------NCALGGQCVKGDRGAPGIPGSPGSRG 1040

Query: 678  EKGSSWRNWPGEA-----KARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSL 732
            + G      PG +     K  P  +     PGP  P       G +   R    KP   L
Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG-NPGERGPPGKP--GL 1097

Query: 733  DDVFLPKDMDGVEMD 747
              +  P D++ +  D
Sbjct: 1098 SSLLSPGDINLLAKD 1112



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 58/213 (27%), Positives = 77/213 (36%), Gaps = 43/213 (20%)

Query: 507  GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPP--PGIVPENGLVRRLNTVPNLSRVI 564
            GSP +  L  PG P P     R   P     RGPP  PG+      +     +  L++ +
Sbjct: 1060 GSPGSRGL--PGFPGPQGPAGRDGAPGNPGERGPPGKPGL----SSLLSPGDINLLAKDV 1113

Query: 565  WVKTPK--PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASP--AP 620
                P   PG P                LP      G P K  R+G++ KK EA P   P
Sbjct: 1114 CNDCPPGPPGLPG---------------LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 1158

Query: 621  RPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG-PGWAGSPKTEKEK 679
             PP           +AGP+  G   E    G   + G+      PG  G  G+P      
Sbjct: 1159 GPPG----------IAGPQ--GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 1206

Query: 680  GSSWRNWPGEAKARPQEQESVQPPGPARPQSLP 712
            G +    P   +  P ++    PPGP  P  LP
Sbjct: 1207 GIAGAAGPPGIQGSPGKE---GPPGPQGPSGLP 1236



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 35/145 (24%), Positives = 45/145 (31%), Gaps = 15/145 (10%)

Query: 572  GYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631
            G P  E P   + PS    +P      G+  K    G   K  E    P P  +   P  
Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG-LPGPEGARGPPGF 1277

Query: 632  KGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAK 691
            KG       PG                G  G+   PG  G P  + + G +    P   +
Sbjct: 1278 KGHTGDSGAPGP--------------RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323

Query: 692  ARPQEQESVQPPGPARPQSLPQGKG 716
              P +  S   PG   P   P  KG
Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKG 1348



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 16/150 (10%)

Query: 571 PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPS 630
           PG P  +   SK +     EL EP    G P +   +G Q         P PP  +  P 
Sbjct: 538 PGPPGRD--GSKGMRGEPGELGEP----GLPGEVGMRGPQGPPG----LPGPPGRVGAPG 587

Query: 631 AKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690
            +G+       G   E    G   + G+  +  RPGP     P  + EKG      P   
Sbjct: 588 LQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP--QGEKGDVGPAGPPGV 645

Query: 691 KARPQEQESVQ----PPGPARPQSLPQGKG 716
                +QE ++     PGP   Q  P   G
Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 51/172 (29%), Positives = 65/172 (37%), Gaps = 46/172 (26%)

Query: 571  PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGS-------QAKKSEASPAPRPP 623
            PG     EP  +  P     LP P+  G K   GK +GS       Q  K +   AP  P
Sbjct: 981  PGKGKDGEPGLRGSPG----LPGPL--GTKAACGKVRGSENCALGGQCVKGDRG-APGIP 1033

Query: 624  ASLEVPSAKGQ----VAGPKQPGRVLELPKVGSCAEAGEGSRGSR-----PGP----GWA 670
             S   P ++G     VAGP  P          S     +GS GSR     PGP    G  
Sbjct: 1034 GS---PGSRGDPGIGVAGPPGP----------SGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080

Query: 671  GSPKTEKEKGSSWRNW------PGEAKARPQEQESVQPPGPARPQSLPQGKG 716
            G+P    E+G   +        PG+     ++  +  PPGP     LP  KG
Sbjct: 1081 GAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG 1132



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 31/93 (33%), Positives = 37/93 (39%), Gaps = 7/93 (7%)

Query: 628 VPSAKGQVA--GPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR 684
           +P  KG +   GP   PG   E   VG     G+G +G +   G  G P  +  KG   R
Sbjct: 494 LPGPKGDIGAIGPVGAPGPKGEKGDVG-IGPFGQGEKGEKGSLGLPGPPGRDGSKG--MR 550

Query: 685 NWPGEAKARPQEQESVQPPGPARPQSLPQGKGR 717
             PGE    P     V   GP  P  LP   GR
Sbjct: 551 GEPGEL-GEPGLPGEVGMRGPQGPPGLPGPPGR 582



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 18/148 (12%)

Query: 571 PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPR--PPASLEV 628
           PG P S     +E    +Q  P P    G P      G    +    P  R  PP    +
Sbjct: 643 PGVPGSVV--QQEGLKGEQGAPGPRGHQGAP------GPPGARGPIGPEGRDGPPGLQGL 694

Query: 629 PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPG 688
              KG +  P  PG +      G     G       PGPG  GSP    E G   +  P 
Sbjct: 695 RGKKGDMGPPGIPGLL------GLQGPPGPPGVPGPPGPG--GSPGLPGEIGFPGKPGPP 746

Query: 689 EAKARPQEQESVQPPGPARPQSLPQGKG 716
                P +     PPGP   +  P  +G
Sbjct: 747 GPTGPPGKDGPNGPPGPPGTKGEPGERG 774



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 53/209 (25%), Positives = 71/209 (33%), Gaps = 47/209 (22%)

Query: 517 PGEPAPPWAE----MRGPHPPWTEVRGPP-----PGIVPENGLVRRLNTVPNLSRVIWVK 567
           PG+P PP         GP+ P     GPP     PG   E+GL  +    P L   I  +
Sbjct: 740 PGKPGPPGPTGPPGKDGPNGP----PGPPGTKGEPGERGEDGLPGK----PGLRGEIGEQ 791

Query: 568 --TPKPGYPSSEE-PSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP-- 622
               +PG       P +   P  + E  +    G     G + G + +K EA PA  P  
Sbjct: 792 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK-GDRGEKGEAGPAGPPGL 850

Query: 623 --PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKG 680
               SL  P        P+ PG               +G +G +  PG  G P  +   G
Sbjct: 851 PGTTSLFTPH-------PRMPGE--------------QGPKGEKGDPGLPGEPGLQGRPG 889

Query: 681 SSWRNWP-GEAKARPQEQESVQPPGPARP 708
                 P G   A+ QE     P     P
Sbjct: 890 ELGPQGPTGPPGAKGQEGAHGAPGAAGNP 918



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 52/221 (23%), Positives = 78/221 (35%), Gaps = 35/221 (15%)

Query: 476  EPEPQSLPPSNLSGSSEQQPDINLDLSPL-TLGSPQNHTLQA----PGEPAPPWAEMRGP 530
            EP P   P    S      P +   L P    G P    +      PG+P  P  +    
Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396

Query: 531  HPPWTEVRGPP--------PGIVPENGLVRRLNT--VPNLSRVIWVKTP--KPGYPS--S 576
             P     +GPP        PGI    G    +    +P  +  +    P  +PG+P    
Sbjct: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456

Query: 577  EEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVA 636
            E PS + +    QE           + GK+  ++     A     PPA ++  S++G+  
Sbjct: 1457 ESPSMETLRRLIQE-----------ELGKQLETRLAYLLAQ---MPPAYMK--SSQGRPG 1500

Query: 637  GPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEK 677
             P  PG+     + G   E G   +G   GP     PK E+
Sbjct: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 66/233 (28%), Positives = 88/233 (37%), Gaps = 45/233 (19%)

Query: 487 LSGSSEQQPDINLDLSPLTL-GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIV 545
           LS +     D++ + S   + G P+    Q   +P  P      P PP     G P G  
Sbjct: 13  LSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRP------PPPP-----GKPQGPP 61

Query: 546 PENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGK 605
           P+ G         N S+      P PG P    P          +   P    GKP++  
Sbjct: 62  PQGG---------NQSQG---PPPPPGKPEGRPPQGGN------QSQGPPPHPGKPERPP 103

Query: 606 RQGSQAKKSEASPAPRPPASLEVPSAKGQVAG---PKQPGRVLELPKVGSCAEAGEGSRG 662
            QG     +++   P PP   E P  +G       P  PG+    P  G     G  S+G
Sbjct: 104 PQGG----NQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQG-----GNQSQG 154

Query: 663 SRPGPGWA-GSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQG 714
             P PG   G P  E  K  S R+ PG+ +  PQ QE  +P GP  P   PQG
Sbjct: 155 PPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQ-QEGNKPQGPP-PPGKPQG 205



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 29/174 (16%)

Query: 575 SSEEPSSKE---VPSCKQELPEPVSSGGKPQK-----GKRQGSQAKKSEASPAPRPPASL 626
           SSE+ S +E   + S K E   P   G +PQ+     GK QG   +    S  P PP   
Sbjct: 19  SSEDVSQEESLFLISGKPEGRRP-QGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGK 77

Query: 627 ---EVPSAKGQVAGPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682
                P    Q  GP   PG+    P  G     G  S+G+ P PG    P+    +G +
Sbjct: 78  PEGRPPQGGNQSQGPPPHPGKPERPPPQG-----GNQSQGTPPPPG---KPERPPPQGGN 129

Query: 683 WRNWPGEAKARPQE-------QESVQPPGPARPQSLPQGKG-RSRRSRNKQEKP 728
             + P     +P+        Q    PP P +P+  P  +G +SR +R+   KP
Sbjct: 130 QSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKP 183



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 43/163 (26%), Positives = 51/163 (31%), Gaps = 24/163 (14%)

Query: 98  PHSSGAMPGSSLGSPPTIPG--EAFPVSEHHQHSDLTAPPNSPT---------GHHPQPA 146
           P       G+    PP  PG  E  P    +Q      PP  P           H P P 
Sbjct: 78  PEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP 137

Query: 147 SLIPSHP------SSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSS-HL 199
              P  P       S G PPHP      P  P P + ++   A +      GP Q   + 
Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPG----KPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNK 193

Query: 200 PSTSMPLLKM--PPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
           P    P  K   PPP  G          G   GP  PP   +P
Sbjct: 194 PQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRP 236



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 54/198 (27%), Positives = 62/198 (31%), Gaps = 39/198 (19%)

Query: 61  SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGL----WNSPHSSGAMPGSSLGSPPTIP 116
           SS+ SSS   S         + S FL + K  G      N P      PG   G PP   
Sbjct: 14  SSAESSSEDVSQ--------EESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPP--- 62

Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFP-- 174
                    +Q      PP  P G  PQ  +       S G PPH    P  P  P P  
Sbjct: 63  ------QGGNQSQGPPPPPGKPEGRPPQGGN------QSQGPPPH----PGKPERPPPQG 106

Query: 175 ---AQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGP 231
              +Q +  P      P   G  Q SH P       + PPP  G          G   GP
Sbjct: 107 GNQSQGTPPPPGKPERPPPQGGNQ-SHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGP 165

Query: 232 LLPPPSSQPLPSTHRDPG 249
             PP       S    PG
Sbjct: 166 --PPQEGNKSRSARSPPG 181


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 59/178 (33%), Positives = 70/178 (39%), Gaps = 20/178 (11%)

Query: 31   TGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHK 90
            TG  +  A S    S  S S    S SSSSSSSSSSSSSSSS   +S     SS  S+  
Sbjct: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656

Query: 91   LSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNS----PTGHHPQPA 146
             S   +S  SS +   +   S  +   EA P          TA P++    PT    Q  
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP--------TAGPSAQAALPTKATKQAG 2708

Query: 147  SLIPS--HPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPST 202
               PS   P      P P   P  P  P        P A A A   P   +  HLP+T
Sbjct: 2709 KARPSAHSPGKKTPAPQPQAPPPQPTQPLQ------PKAQAGAKSRPKKREGVHLPTT 2760



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 41/128 (32%), Positives = 52/128 (40%), Gaps = 6/128 (4%)

Query: 19   SCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSG 78
            S   S       +    + + S S +S  S S    S SSSSSSSSSSSSSSSS   ++ 
Sbjct: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673

Query: 79   DWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAP-PNS 137
            D D S              P +  A+P  +        G+A P S H       AP P +
Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ----AGKARP-SAHSPGKKTPAPQPQA 2728

Query: 138  PTGHHPQP 145
            P     QP
Sbjct: 2729 PPPQPTQP 2736



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 52/189 (27%), Positives = 73/189 (38%), Gaps = 33/189 (17%)

Query: 49   QSCGDDSHSSSSSSSSSSSSSSSSCPGNS-------GDWD--------------PSSFLS 87
            Q   ++S SSSSSSS SSSSSSSS    S       GD +               SS  +
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610

Query: 88   AHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPAS 147
            +   S   +S  SS +   SS  S  +    +   S     S  ++  +S +      +S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670

Query: 148  LIPSHPSSFGS----PPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTS 203
                  SS  S     P P   P+  AA  P +A++    A  + H+PG         T 
Sbjct: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAA-LPTKATKQAGKARPSAHSPG-------KKTP 2722

Query: 204  MPLLKMPPP 212
             P  + PPP
Sbjct: 2723 APQPQAPPP 2731



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 57/209 (27%), Positives = 79/209 (37%), Gaps = 28/209 (13%)

Query: 105  PGSSLGSPPTIPGEA-FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPH 163
            PGS    P  +   A  P +         APP   +   P+P + +P+  +S    P   
Sbjct: 2370 PGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAP--- 2426

Query: 164  LLPTTPAA-PFPAQASECPVAAATAPHTPGP-----CQSSHLPSTSMP--------LLKM 209
             L T PA  P P +A     + A  P  PG       +  H   TS          LL+ 
Sbjct: 2427 -LITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRE 2485

Query: 210  PPPFSGCSHPCSGHCGGH------CSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQ 263
             P   G   P S    G        S P  P P +       ++PG  G  F  SG   +
Sbjct: 2486 DPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATD-GDLAQEPG-PGLTFEDSGNP-K 2542

Query: 264  LPQPCEADEGLGEEEDSSSERSSCTSSST 292
             P   +A++   EE +SSS  SS +SSS+
Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSS 2571



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 72/308 (23%), Positives = 100/308 (32%), Gaps = 71/308 (23%)

Query: 475  AEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPW 534
            AEP P  L PS    S +   D        T GS +    +A G    P A+ +G     
Sbjct: 2289 AEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGA-KARGRGRKPSAKAKGDRAAT 2347

Query: 535  TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEP 594
             E   P   +                          P  P + EPSS   P  K+  PEP
Sbjct: 2348 LEEGNPTDEV--------------------------PSTPLALEPSS--TPGSKKSPPEP 2379

Query: 595  VSSGGKPQKGKRQGSQAKKSEASPA-----PRPPA--SLEVPSAKGQVAGPK---QPGRV 644
            V              +AK  +A PA     P PPA  S   P    ++  P     P  +
Sbjct: 2380 VDK------------RAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427

Query: 645  LEL------PKVGSCAEAGEGSRGSRPGP----------GWAGSPKTEKEKGS-SWRNWP 687
            + +      PK    AE        RPG               SPK++K K +   R  P
Sbjct: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487

Query: 688  GEAK-ARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSL--DDVFLPKDMDGV 744
            G      P+   S+    PA   S P+         +  ++P   L  +D   PK  D  
Sbjct: 2488 GAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKA 2547

Query: 745  EMDETDRE 752
            + ++   E
Sbjct: 2548 QAEQDGAE 2555


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 41/124 (33%), Positives = 50/124 (40%), Gaps = 15/124 (12%)

Query: 133 APPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG 192
           APP +P G    PA+   + P    +PP P   P   AA  PA+A     AAATAP +PG
Sbjct: 110 APPRAPRG---APAAAAAAAPPPTPAPPPP---PAPVAAAAPARAPRAAAAAATAPPSPG 163

Query: 193 PCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGH--------CSGPLLPPPSSQPLPST 244
           P Q       + P L  PPP        +   G             P LPPP   P P  
Sbjct: 164 PAQPGPRAQRAAP-LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222

Query: 245 HRDP 248
            + P
Sbjct: 223 QQQP 226



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 63/261 (24%), Positives = 88/261 (33%), Gaps = 43/261 (16%)

Query: 520 PAPPWAEMRGPH------PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGY 573
           PAPP A    P       PP T    PPP  V      R     P  +       P PG 
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR----APRAAAAAATAPPSPGP 164

Query: 574 ----PSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVP 629
               P ++  +    P      P  V+    P++       A++    P P+PPA     
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA----- 219

Query: 630 SAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSR--------PGPGWAGSPKT------ 675
             + Q   P QP    + P  G    AG  +R            G G AG   T      
Sbjct: 220 PPQQQQPPPPQP----QPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275

Query: 676 --EKE---KGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730
             E+E   +G   R   G A A P+     + P  A  +     +G   R   K+E+   
Sbjct: 276 LLEEEAAARGRLERTRLG-ALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDD 334

Query: 731 SLDDVFLPKDMDGVEMDETDR 751
             D+       +G E+ E+DR
Sbjct: 335 DEDEDEEDDVSEGSEVPESDR 355



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 74/333 (22%), Positives = 105/333 (31%), Gaps = 81/333 (24%)

Query: 100 SSGAMPGSSLGSPPTIP-GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGS 158
           ++ A P +    PP  P   A P       +     P SP    P P +      +   +
Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRA---QRAAPLAA 179

Query: 159 PPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSH 218
           PP     P   A P   + +  P  AA  P  P P Q    P    P    P P      
Sbjct: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP------ 233

Query: 219 PCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEE 278
           P  G  G   +G    P S + +       G  G +     +           +GL EEE
Sbjct: 234 PPEG--GAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRV-----------QGLLEEE 280

Query: 279 DSSSERSSCT-----SSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRL 333
            ++  R   T     +     R G+             APPAA  S   +  +     R+
Sbjct: 281 AAARGRLERTRLGALALPRGDRPGR-------------APPAA--SARPSRSKRGGEERV 325

Query: 334 TRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKE 393
             ++EE                 +  D DE  E   S   +VP S R A    H+L    
Sbjct: 326 LEKEEE-----------------EDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQL---- 364

Query: 394 KEKAQLAAEALKQANRVSGSREPRPARERLLEW 426
                            +G R P+ A+ER+ EW
Sbjct: 365 -----------------NGERGPQSAKERVKEW 380



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 33/128 (25%), Positives = 39/128 (30%), Gaps = 8/128 (6%)

Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVG- 651
           +P   G  P    R    A  + A+ AP P  +   P A    A P +  R         
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159

Query: 652 -SCAEAGEGSRGSR------PGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPG 704
            S   A  G R  R      P P  A  P      G      P  A   P      QPP 
Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219

Query: 705 PARPQSLP 712
           P + Q  P
Sbjct: 220 PPQQQQPP 227


>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
          Length = 379

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 61/244 (25%), Positives = 82/244 (33%), Gaps = 39/244 (15%)

Query: 483 PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTL-QAPGEPAPPWAEMRGPHPPWTEVRGPP 541
           P     G+ E  P     L+   L  P+  +L   PGE A     +RGP  P       P
Sbjct: 25  PRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAP 84

Query: 542 PGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKP 601
            G+                 + +W  T +PG P++      +V +C +   E    GG P
Sbjct: 85  DGL-----------------KHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFP 127

Query: 602 QKGKRQGS------------QAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPK 649
             G R  +            ++  S AS  PRP   LE P      + P++P      P 
Sbjct: 128 HFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLE-PQRGPAASPPQEPSSRPPSPP 186

Query: 650 VGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQ 709
            G   E          GPG A  P    +      N P  A   P    S   P PA P 
Sbjct: 187 AGLSTEPA--------GPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPG 238

Query: 710 SLPQ 713
            L Q
Sbjct: 239 DLRQ 242



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 10/80 (12%)

Query: 127 QHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA----PFPAQASECPV 182
           Q     +PP  P+   P P + + + P+  G+ P P  LP  PA     P PA A E P 
Sbjct: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRP-FLPGQPAEVDGNPPPA-APEAPA 224

Query: 183 A----AATAPHTPGPCQSSH 198
           A    A+ AP  PG  +  H
Sbjct: 225 ASPSTASPAPAAPGDLRQEH 244



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 35/137 (25%), Positives = 44/137 (32%), Gaps = 39/137 (28%)

Query: 116 PGEAFPVSEHHQHSDLT---APPNSPTGHHPQ--PASLIPSHPSSFGSPPHPHLLPTTPA 170
           PG   P   H + S  +   APP    G  PQ  PA+  P  PSS   PP P        
Sbjct: 137 PGRC-PAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS--RPPSP-------- 185

Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230
                     P   +T P  PG      LP     +   PPP +                
Sbjct: 186 ----------PAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAP-------------EA 222

Query: 231 PLLPPPSSQPLPSTHRD 247
           P   P ++ P P+   D
Sbjct: 223 PAASPSTASPAPAAPGD 239


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 70/272 (25%), Positives = 112/272 (41%), Gaps = 42/272 (15%)

Query: 50   SCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSL 109
            S G  SH S SSSSSSS+S+S     +  +   SS LS    S +++S  SSG+    + 
Sbjct: 1091 SSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLS----SSMYSSQGSSGSSQSKNS 1146

Query: 110  GSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLI----------PSH------P 153
                  PG + P+++H   S  ++    P G   +P+SL+          PSH       
Sbjct: 1147 SQSGGKPGSS-PITKHGLSSGSSSTKMKPQG---KPSSLMNPSLSKPNISPSHSRPPGGS 1202

Query: 154  SSFGSPPHPHLLPTTPAAPFPAQASECPVAAAT-APHTPGPCQSSHLPSTS------MPL 206
                SP  P  +P TP    P+  ++ P+++ +   H  G   SS + S+S         
Sbjct: 1203 DKLASPMKP--VPGTP----PSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256

Query: 207  LKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQ 266
             K PP  + C+   S       SG  +    +Q   S  + P  +  K + + +  +L  
Sbjct: 1257 QKTPPSSNSCTASSSSFSS---SGSSMSSSQNQHGSSKGKSPS-RNKKPSLTAVIDKLKH 1312

Query: 267  PCEADEGLGEEEDSSSERSSCTSSSTHQRDGK 298
                  G G E+    +    T+SS+H    K
Sbjct: 1313 GV-VTSGPGGEDPLDGQMGVSTNSSSHPMSSK 1343



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 45/180 (25%), Positives = 63/180 (35%), Gaps = 17/180 (9%)

Query: 567  KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASL 626
            K PK     +E  S     S +   P P S+GG    G    SQ     A+P P P  ++
Sbjct: 1008 KPPKRKKADTEGKSPSHSSSNRPFTP-PTSTGGSKSPGSAGRSQTPPGVATP-PIPKITI 1065

Query: 627  EVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSR--GSRPGPGWAGSPKTEKEKGSSWR 684
            ++P     V  P    +      V S       S    S      +G  K+ K +GSS  
Sbjct: 1066 QIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125

Query: 685  NWPGE------AKARPQEQESVQPPGPARPQSLPQGK-----GRSRRSRNKQEKPASSLD 733
                       +    Q + S Q  G  +P S P  K     G S      Q KP+S ++
Sbjct: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGG--KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMN 1183


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 72/275 (26%), Positives = 102/275 (37%), Gaps = 53/275 (19%)

Query: 470 SKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPLTLGSPQNHTLQAPGEPAPPWAEMR 528
           S+ G A+P  Q   PS L+    QQP  +   + P     P    L     PA P A+  
Sbjct: 324 SQPGPAKPPAQ---PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG----PAKPPAQQT 376

Query: 529 GPHPPWTEVRGP-----PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKE 583
           G   P +E  GP     PPG+    G        P       V TPKP    +++P  + 
Sbjct: 377 GSEKPSSEQPGPKALAQPPGV----GKTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQS 429

Query: 584 VPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP-RPPASLEVPSAKGQVAGPKQPG 642
                     PV   G  +   +Q    K S     P +PP+ L  P+       P+QPG
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP----PQQPG 485

Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR---NWPGEAKARPQEQES 699
                               ++P P   GS K   ++  S +     PG AK  PQ+  S
Sbjct: 486 P-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 700 VQP----PGPARPQSLPQGKGRSRRSRNKQEKPAS 730
            +P    PG A+P +  Q    ++ S  +  KP S
Sbjct: 527 TKPPSQQPGSAKPSA--QQPSPAKPSAQQSTKPVS 559



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 133/601 (22%), Positives = 196/601 (32%), Gaps = 111/601 (18%)

Query: 112 PPTIPGE-AFPVSEHHQHSDLTAPPNS------PTGHHPQPASLIPSHPSSFGSPPH-PH 163
           P  IP + A P     Q +  T PP+       P    P PA   P  P S   P   P 
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 164 LLPTTPAAPFPAQASECPVAAATAPHTPGPCQS-SHLPSTSMPLLKMPPPFSGCSHPCSG 222
                P  P PA+ S         P  PG  +  S  P ++ P  + P P    +   + 
Sbjct: 506 STKPPPQQPGPAKPS---------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 223 HCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSS 282
                 SG  L PP+  P  S  + P          GL   +   C   E L    + ++
Sbjct: 557 PVSQTGSGKPLQPPTVSP--SAKQPPS--------QGLPKTICPLCNTTELLLHVPEKAN 606

Query: 283 ERSSCTSSST------------HQRDGKFCDCCYCEFF----GHNAP-PAAP-------- 317
             ++CT   T            H  + K   C  C+      G  AP P++P        
Sbjct: 607 F-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665

Query: 318 ----------------TSRNYTEIREKLRSRLTRRKEELPM-KGGTLGGIPGEPAVDHRD 360
                           TS       ++  S+    K+  P+ K  TL G P   A    +
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725

Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420
            D L +     EP VP+               E++KA +A +  KQ   V  + +   + 
Sbjct: 726 ADSLSKPAPPKEPSVPS---------------EQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480
               + PD    +V S    +      T  DS + S S        + F  +    P   
Sbjct: 771 SATTK-PDIPSSKVQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827

Query: 481 SLPPSNLSGSSEQQPDINLD--------LSPLTLGSPQNHTLQAP-GEPAPPWAEMRGPH 531
           S   S+   SSE +    +D            T  SP+      P G P PP     GP 
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPR 882

Query: 532 PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEV---PSCK 588
           P   +    P          RR +   NL  +      +P  P  E  + K      S  
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSL--NLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIF 939

Query: 589 QELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELP 648
            +    +S+ G+P    + G  A   +A    +PP S   P + GQ   P  P + + + 
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVK 997

Query: 649 K 649
           K
Sbjct: 998 K 998



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/426 (20%), Positives = 147/426 (34%), Gaps = 64/426 (15%)

Query: 336 RKEEL----PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPN---SARAAKRARHK 388
           RK+EL    P K       PG PA          +   S E K+P    S  + K ++ +
Sbjct: 83  RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRS-EQKLPGRSPSTISLKESKSR 141

Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSF---LSSRLQEI 445
              KE+ K+ +    L + N +S                   +++ N F     S   + 
Sbjct: 142 TDLKEEHKSSMMPGFLSEVNALSAVSSV--------------VNKFNPFDLISDSEASQE 187

Query: 446 KNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPL 504
           + T K  +          +       EG  +P  Q  PP  +        D +  D +P 
Sbjct: 188 ETTKKQKV----------VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK 237

Query: 505 TLGSPQNHTL--QAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPEN---GLVRRLNTVPN 559
           ++ S Q   +  Q PG   P     + P     ++        P+     +VR  +  P+
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 560 LSRVIW--VKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEAS 617
           L       ++ P PG P +++P  ++        P P     +P  G  +    +     
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK------SQPGPAKPPAQPS-GLTKPLAQQPGTVK 350

Query: 618 PAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG--------PGW 669
           P  +PP + + P+   Q  GP +P       +  S  + G  +    PG        PG 
Sbjct: 351 PPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407

Query: 670 AGSPKTEKEKGSSWRNWPG---EAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQE 726
           A  P  +          PG    AKA    +  VQ PGP +  +   G G++   +    
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 727 KPASSL 732
           KP S L
Sbjct: 468 KPPSQL 473



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 142/687 (20%), Positives = 219/687 (31%), Gaps = 121/687 (17%)

Query: 97  SPHSSGAMPG-SSLGSPPTI-------PGEAFPVSEH-------HQHSDLTAPPNSPTG- 140
           S   S   PG  +L  PP +       PG A P ++         Q   L +P  +P   
Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 141 ----HHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS 196
                 P P   IP+  +  G        PT P +  P  A   P     A   P    S
Sbjct: 438 KTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496

Query: 197 SHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP---LPSTHRDPGCKGH 253
           +  PS      K PP   G + P S    G    P   P S++P    PS  +    +  
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKP-SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555

Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ------RDGKF-----CDC 302
           K      + +  QP        +       ++ C   +T +          F     C  
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615

Query: 303 CYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVD 362
             C   G N  P      + TE++E L      ++      GG L  +P  P        
Sbjct: 616 TVCSLCGFNPNP------HLTEVKEWLCLNCQMKR----ALGGDLAPVPSSP-------- 657

Query: 363 ELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARER 422
                    +PK+  +      A  K   + ++ +     A KQ      S+ P P +  
Sbjct: 658 ---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----DLSKAPEPKKPP 704

Query: 423 LLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSL 482
            L                        VK          +        S    A P+  S+
Sbjct: 705 PL------------------------VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 483 PPSN----LSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVR 538
           P       ++    +QP +    + L   S        P       AE +   P  T+  
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800

Query: 539 GPPPGIVPENGLVRRLNT--VP---NLSRVIWVKTPKPGYPSSEEPSSKEV-PSCKQELP 592
            P     P    V   ++  +P   + S++I      PG PSSE    K+V P  K+E P
Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKII----SHPG-PSSESKGQKQVDPVQKKEEP 855

Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGS 652
           +   +   P+   +     K S   P PRP A   VP+ + Q   P++  R   L  +GS
Sbjct: 856 KKAQTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPTPQ-QSPKPQEQSRRFSL-NLGS 911

Query: 653 CAEAGEGSRGSRPGP-------GWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705
             +A + S+ + P         G+  S  ++     S    PG            Q P P
Sbjct: 912 ITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970

Query: 706 ARPQSLPQGKGRSRRSRNKQEKPASSL 732
           ++P   P  +G  + +      PA S+
Sbjct: 971 SQP---PTSQGPPKSTGQAPPAPAKSI 994



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 53/193 (27%), Positives = 67/193 (34%), Gaps = 30/193 (15%)

Query: 79   DWDPSSFLSAHKLSGLWNSPHSSGAM-----PGSSL--GSPPTIPGEAFPVSEHHQHS-D 130
            D  PSS ++      L  +  +SG       P S L  GSP      A P       S D
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400

Query: 131  LTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA------- 183
            ++A P  P    P P    P        PP P L P T   P      +  VA       
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453

Query: 184  ----AATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ 239
                A T   T    +S+ LP T +     PP     S   SG    H   P  PP + +
Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513

Query: 240  P----LPSTHRDP 248
            P    LP+T + P
Sbjct: 2514 PVIPQLPTTTQKP 2526



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 11/130 (8%)

Query: 112 PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH-PHLLPTTPA 170
           P  IP +  P  +  Q       P S +   P+    I S P   G P   P   P T  
Sbjct: 216 PKPIPKQQGPGRDPLQQD---GTPKSISSQQPEK---IKSQPPGTGKPIQGPTQTPQTDH 269

Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230
           A  P Q          A    G      LPS S P ++ P P      P +   G   S 
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP----GKPPAQQPGHEKSQ 325

Query: 231 PLLPPPSSQP 240
           P    P +QP
Sbjct: 326 PGPAKPPAQP 335



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 55/248 (22%), Positives = 75/248 (30%), Gaps = 34/248 (13%)

Query: 9   LGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSS 68
           L E+  W+C +C+      +R  G + A   S      K+      S  S SS     +S
Sbjct: 629 LTEVKEWLCLNCQM-----KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683

Query: 69  SSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH 128
                     D  P   LS         +P      P   L   PT+ G     ++    
Sbjct: 684 PKK-------DAAPKQDLS--------KAPEPKKPPP---LVKQPTLHGSPSAKAKQPPE 725

Query: 129 SDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAP 188
           +D  + P  P           PS PS     P     P  P    P        +A T P
Sbjct: 726 ADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 189 HTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDP 248
             P     S     + P LK        S P +G          +P P+S     +H  P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836

Query: 249 G--CKGHK 254
               KG K
Sbjct: 837 SSESKGQK 844



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 25/167 (14%)

Query: 577  EEPSSKEVPSCKQEL-PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQV 635
            E    K+  S  QE  P P      P++ K +  + K       P P     +P AK   
Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK--T 1254

Query: 636  AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695
            + P++    L   +V    E  EG            +PKT +E         G     PQ
Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLEGRV----------APKTVQEGKQPQTKMEGLPSGTPQ 1304

Query: 696  E------------QESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730
                         +E  QPP  A+P  +  GK ++ +  +K +  +S
Sbjct: 1305 SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 72/275 (26%), Positives = 102/275 (37%), Gaps = 53/275 (19%)

Query: 470 SKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPLTLGSPQNHTLQAPGEPAPPWAEMR 528
           S+ G A+P  Q   PS L+    QQP  +   + P     P    L     PA P A+  
Sbjct: 324 SQPGPAKPPAQ---PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG----PAKPPAQQT 376

Query: 529 GPHPPWTEVRGP-----PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKE 583
           G   P +E  GP     PPG+    G        P       V TPKP    +++P  + 
Sbjct: 377 GSEKPSSEQPGPKALAQPPGV----GKTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQS 429

Query: 584 VPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP-RPPASLEVPSAKGQVAGPKQPG 642
                     PV   G  +   +Q    K S     P +PP+ L  P+       P+QPG
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP----PQQPG 485

Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR---NWPGEAKARPQEQES 699
                               ++P P   GS K   ++  S +     PG AK  PQ+  S
Sbjct: 486 P-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 700 VQP----PGPARPQSLPQGKGRSRRSRNKQEKPAS 730
            +P    PG A+P +  Q    ++ S  +  KP S
Sbjct: 527 TKPPSQQPGSAKPSA--QQPSPAKPSAQQSTKPVS 559



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 133/601 (22%), Positives = 196/601 (32%), Gaps = 111/601 (18%)

Query: 112 PPTIPGE-AFPVSEHHQHSDLTAPPNS------PTGHHPQPASLIPSHPSSFGSPPH-PH 163
           P  IP + A P     Q +  T PP+       P    P PA   P  P S   P   P 
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 164 LLPTTPAAPFPAQASECPVAAATAPHTPGPCQS-SHLPSTSMPLLKMPPPFSGCSHPCSG 222
                P  P PA+ S         P  PG  +  S  P ++ P  + P P    +   + 
Sbjct: 506 STKPPPQQPGPAKPS---------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 223 HCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSS 282
                 SG  L PP+  P  S  + P          GL   +   C   E L    + ++
Sbjct: 557 PVSQTGSGKPLQPPTVSP--SAKQPPS--------QGLPKTICPLCNTTELLLHVPEKAN 606

Query: 283 ERSSCTSSST------------HQRDGKFCDCCYCEFF----GHNAP-PAAP-------- 317
             ++CT   T            H  + K   C  C+      G  AP P++P        
Sbjct: 607 F-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665

Query: 318 ----------------TSRNYTEIREKLRSRLTRRKEELPM-KGGTLGGIPGEPAVDHRD 360
                           TS       ++  S+    K+  P+ K  TL G P   A    +
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725

Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420
            D L +     EP VP+               E++KA +A +  KQ   V  + +   + 
Sbjct: 726 ADSLSKPAPPKEPSVPS---------------EQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480
               + PD    +V S    +      T  DS + S S        + F  +    P   
Sbjct: 771 SATTK-PDIPSSKVQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827

Query: 481 SLPPSNLSGSSEQQPDINLD--------LSPLTLGSPQNHTLQAP-GEPAPPWAEMRGPH 531
           S   S+   SSE +    +D            T  SP+      P G P PP     GP 
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPR 882

Query: 532 PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEV---PSCK 588
           P   +    P          RR +   NL  +      +P  P  E  + K      S  
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSL--NLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIF 939

Query: 589 QELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELP 648
            +    +S+ G+P    + G  A   +A    +PP S   P + GQ   P  P + + + 
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVK 997

Query: 649 K 649
           K
Sbjct: 998 K 998



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/426 (20%), Positives = 147/426 (34%), Gaps = 64/426 (15%)

Query: 336 RKEEL----PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPN---SARAAKRARHK 388
           RK+EL    P K       PG PA          +   S E K+P    S  + K ++ +
Sbjct: 83  RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRS-EQKLPGRSPSTISLKESKSR 141

Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSF---LSSRLQEI 445
              KE+ K+ +    L + N +S                   +++ N F     S   + 
Sbjct: 142 TDLKEEHKSSMMPGFLSEVNALSAVSSV--------------VNKFNPFDLISDSEASQE 187

Query: 446 KNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPL 504
           + T K  +          +       EG  +P  Q  PP  +        D +  D +P 
Sbjct: 188 ETTKKQKV----------VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK 237

Query: 505 TLGSPQNHTL--QAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPEN---GLVRRLNTVPN 559
           ++ S Q   +  Q PG   P     + P     ++        P+     +VR  +  P+
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 560 LSRVIW--VKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEAS 617
           L       ++ P PG P +++P  ++        P P     +P  G  +    +     
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK------SQPGPAKPPAQPS-GLTKPLAQQPGTVK 350

Query: 618 PAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG--------PGW 669
           P  +PP + + P+   Q  GP +P       +  S  + G  +    PG        PG 
Sbjct: 351 PPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407

Query: 670 AGSPKTEKEKGSSWRNWPG---EAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQE 726
           A  P  +          PG    AKA    +  VQ PGP +  +   G G++   +    
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 727 KPASSL 732
           KP S L
Sbjct: 468 KPPSQL 473



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 142/687 (20%), Positives = 219/687 (31%), Gaps = 121/687 (17%)

Query: 97  SPHSSGAMPG-SSLGSPPTI-------PGEAFPVSEH-------HQHSDLTAPPNSPTG- 140
           S   S   PG  +L  PP +       PG A P ++         Q   L +P  +P   
Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 141 ----HHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS 196
                 P P   IP+  +  G        PT P +  P  A   P     A   P    S
Sbjct: 438 KTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496

Query: 197 SHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP---LPSTHRDPGCKGH 253
           +  PS      K PP   G + P S    G    P   P S++P    PS  +    +  
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKP-SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555

Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ------RDGKF-----CDC 302
           K      + +  QP        +       ++ C   +T +          F     C  
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615

Query: 303 CYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVD 362
             C   G N  P      + TE++E L      ++      GG L  +P  P        
Sbjct: 616 TVCSLCGFNPNP------HLTEVKEWLCLNCQMKR----ALGGDLAPVPSSP-------- 657

Query: 363 ELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARER 422
                    +PK+  +      A  K   + ++ +     A KQ      S+ P P +  
Sbjct: 658 ---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----DLSKAPEPKKPP 704

Query: 423 LLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSL 482
            L                        VK          +        S    A P+  S+
Sbjct: 705 PL------------------------VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 483 PPSN----LSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVR 538
           P       ++    +QP +    + L   S        P       AE +   P  T+  
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800

Query: 539 GPPPGIVPENGLVRRLNT--VP---NLSRVIWVKTPKPGYPSSEEPSSKEV-PSCKQELP 592
            P     P    V   ++  +P   + S++I      PG PSSE    K+V P  K+E P
Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKII----SHPG-PSSESKGQKQVDPVQKKEEP 855

Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGS 652
           +   +   P+   +     K S   P PRP A   VP+ + Q   P++  R   L  +GS
Sbjct: 856 KKAQTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPTPQ-QSPKPQEQSRRFSL-NLGS 911

Query: 653 CAEAGEGSRGSRPGP-------GWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705
             +A + S+ + P         G+  S  ++     S    PG            Q P P
Sbjct: 912 ITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970

Query: 706 ARPQSLPQGKGRSRRSRNKQEKPASSL 732
           ++P   P  +G  + +      PA S+
Sbjct: 971 SQP---PTSQGPPKSTGQAPPAPAKSI 994



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 53/193 (27%), Positives = 67/193 (34%), Gaps = 30/193 (15%)

Query: 79   DWDPSSFLSAHKLSGLWNSPHSSGAM-----PGSSL--GSPPTIPGEAFPVSEHHQHS-D 130
            D  PSS ++      L  +  +SG       P S L  GSP      A P       S D
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400

Query: 131  LTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA------- 183
            ++A P  P    P P    P        PP P L P T   P      +  VA       
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453

Query: 184  ----AATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ 239
                A T   T    +S+ LP T +     PP     S   SG    H   P  PP + +
Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513

Query: 240  P----LPSTHRDP 248
            P    LP+T + P
Sbjct: 2514 PVIPQLPTTTQKP 2526



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 11/130 (8%)

Query: 112 PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH-PHLLPTTPA 170
           P  IP +  P  +  Q       P S +   P+    I S P   G P   P   P T  
Sbjct: 216 PKPIPKQQGPGRDPLQQD---GTPKSISSQQPEK---IKSQPPGTGKPIQGPTQTPQTDH 269

Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230
           A  P Q          A    G      LPS S P ++ P P      P +   G   S 
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP----GKPPAQQPGHEKSQ 325

Query: 231 PLLPPPSSQP 240
           P    P +QP
Sbjct: 326 PGPAKPPAQP 335



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 55/248 (22%), Positives = 75/248 (30%), Gaps = 34/248 (13%)

Query: 9   LGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSS 68
           L E+  W+C +C+      +R  G + A   S      K+      S  S SS     +S
Sbjct: 629 LTEVKEWLCLNCQM-----KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683

Query: 69  SSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH 128
                     D  P   LS         +P      P   L   PT+ G     ++    
Sbjct: 684 PKK-------DAAPKQDLS--------KAPEPKKPPP---LVKQPTLHGSPSAKAKQPPE 725

Query: 129 SDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAP 188
           +D  + P  P           PS PS     P     P  P    P        +A T P
Sbjct: 726 ADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 189 HTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDP 248
             P     S     + P LK        S P +G          +P P+S     +H  P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836

Query: 249 G--CKGHK 254
               KG K
Sbjct: 837 SSESKGQK 844



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 25/167 (14%)

Query: 577  EEPSSKEVPSCKQEL-PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQV 635
            E    K+  S  QE  P P      P++ K +  + K       P P     +P AK   
Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK--T 1254

Query: 636  AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695
            + P++    L   +V    E  EG            +PKT +E         G     PQ
Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLEGRV----------APKTVQEGKQPQTKMEGLPSGTPQ 1304

Query: 696  E------------QESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730
                         +E  QPP  A+P  +  GK ++ +  +K +  +S
Sbjct: 1305 SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 28/199 (14%)

Query: 65  SSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP-PTIPGEAFPVS 123
           SS  +  S P   G   PS   +     G   +    G++  S L S  P       P +
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255

Query: 124 EHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA 183
                 D   PP  P G+ P        H  +   PP  +  P  P+ P P+ +S+ P  
Sbjct: 256 PSRALDDKPPPPPPPVGNRPS------IHREAVPPPPPQNNKPPVPSTPRPSASSQAP-P 308

Query: 184 AATAPHTPGPC----------QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLL 233
               P  PGP           ++  LP  ++ L    PP      P  G      SGPL 
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-----PSPGR-----SGPLP 358

Query: 234 PPPSSQPLPSTHRDPGCKG 252
           PPPS +P P     PG  G
Sbjct: 359 PPPSERPPPPVRDPPGRSG 377



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 35/177 (19%)

Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535
           +P P   P  N       +P I+ +  P     PQN+    P  P P  +    P PP  
Sbjct: 263 KPPPPPPPVGN-------RPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPP 313

Query: 536 EVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT---PKPGY------PSSEEPSS--KEV 584
              GPPP + P +        +P  +  +   T   P PG       P SE P    ++ 
Sbjct: 314 SRPGPPP-LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372

Query: 585 PSCKQEL--PEPVSSGGK--------PQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631
           P     L  P PVS  G         PQ   R G  + +S     PRPP   + PSA
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS----GPRPPLPPDRPSA 425



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 49/168 (29%), Positives = 56/168 (33%), Gaps = 42/168 (25%)

Query: 111 SPPTIPGEAFPVSEHHQHS---------------DLTAPPNSPTGHHPQPASLIPSHPSS 155
           SPP+ PG  FPV      S               D+ + P+S     P     I S P +
Sbjct: 142 SPPSGPGR-FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200

Query: 156 FGSPP------HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSH-------LPST 202
            GSPP       P   PT P  PFP        A         P  SS        LP T
Sbjct: 201 RGSPPVPGGPRQPSPGPTPP--PFPGNRG---TALGGGSIRQSPLSSSSPFSNRPPLPPT 255

Query: 203 SMPLL--KMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ--PLPSTHR 246
               L  K PPP      P       H      PPP +   P+PST R
Sbjct: 256 PSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 28/199 (14%)

Query: 65  SSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP-PTIPGEAFPVS 123
           SS  +  S P   G   PS   +     G   +    G++  S L S  P       P +
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255

Query: 124 EHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA 183
                 D   PP  P G+ P        H  +   PP  +  P  P+ P P+ +S+ P  
Sbjct: 256 PSRALDDKPPPPPPPVGNRPS------IHREAVPPPPPQNNKPPVPSTPRPSASSQAP-P 308

Query: 184 AATAPHTPGPC----------QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLL 233
               P  PGP           ++  LP  ++ L    PP      P  G      SGPL 
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-----PSPGR-----SGPLP 358

Query: 234 PPPSSQPLPSTHRDPGCKG 252
           PPPS +P P     PG  G
Sbjct: 359 PPPSERPPPPVRDPPGRSG 377



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 35/177 (19%)

Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535
           +P P   P  N       +P I+ +  P     PQN+    P  P P  +    P PP  
Sbjct: 263 KPPPPPPPVGN-------RPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPP 313

Query: 536 EVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT---PKPGY------PSSEEPSS--KEV 584
              GPPP + P +        +P  +  +   T   P PG       P SE P    ++ 
Sbjct: 314 SRPGPPP-LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372

Query: 585 PSCKQEL--PEPVSSGGK--------PQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631
           P     L  P PVS  G         PQ   R G  + +S     PRPP   + PSA
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS----GPRPPLPPDRPSA 425



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 49/168 (29%), Positives = 56/168 (33%), Gaps = 42/168 (25%)

Query: 111 SPPTIPGEAFPVSEHHQHS---------------DLTAPPNSPTGHHPQPASLIPSHPSS 155
           SPP+ PG  FPV      S               D+ + P+S     P     I S P +
Sbjct: 142 SPPSGPGR-FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200

Query: 156 FGSPP------HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSH-------LPST 202
            GSPP       P   PT P  PFP        A         P  SS        LP T
Sbjct: 201 RGSPPVPGGPRQPSPGPTPP--PFPGNRG---TALGGGSIRQSPLSSSSPFSNRPPLPPT 255

Query: 203 SMPLL--KMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ--PLPSTHR 246
               L  K PPP      P       H      PPP +   P+PST R
Sbjct: 256 PSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%)

Query: 60  SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116
           + S+   S+ S + P   G   P    L A  L      P   G  P +S G  P  T P
Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335

Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176
             A+P      H+ L  P +       QP    P  P+    P H    PTTP    PA 
Sbjct: 336 AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 387

Query: 177 ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
               P A    PH  GP   S   +   P    P       HP S H       PL   P
Sbjct: 388 ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 438

Query: 237 SSQPLPSTHRDP 248
            SQPLPS+   P
Sbjct: 439 QSQPLPSSPAQP 450



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%)

Query: 45  SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95
           S  S+S  D+  S        + S+S S P    N  D D S+    L A      +   
Sbjct: 133 SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 192

Query: 96  NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148
            +P  S A PG+  L +P PT    A P       S     P +PT      H  Q  +L
Sbjct: 193 VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252

Query: 149 IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172
            P  P S   PPHP     L P T     P+AP                           
Sbjct: 253 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312

Query: 173 -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205
                   P QAS+      T+P    P  S  LP++                    +MP
Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372

Query: 206 LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253
            +K PP  P      P +     H SGP        L PPP+ +PL   STH  P     
Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 432

Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294
                  +  LP       GL + ++     +S   +  HQ
Sbjct: 433 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%)

Query: 98  PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135
           P +  AMP   +  PPT P    P  + H+H             ++L  PP         
Sbjct: 365 PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422

Query: 136 -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178
            + P   HP P  L+P     PSS   PP       LP  PA          AP P  A 
Sbjct: 423 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482

Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238
              V     P TP  C     PSTS P      P +    PCS   G   SG  +   SS
Sbjct: 483 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 531

Query: 239 QPLPS 243
            PLP+
Sbjct: 532 CPLPT 536



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%)

Query: 24  MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83
           + ED R +GR    A S S    K+++    +      +SS   S+       + D + +
Sbjct: 48  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107

Query: 84  SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117
              S+ K      S P+S     G S  S                      P+IP     
Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167

Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175
           E+   S   Q      PP   +PTG  P P+S  P      G+P  P   PT  A   P 
Sbjct: 168 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 221

Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234
           Q S     A   P  P  P   +H+        + PP      HP              P
Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 268

Query: 235 PPSSQPLPSTHRDPGCKGH 253
            P  QPL  +   P    H
Sbjct: 269 HPPLQPLTGSAGQPSAPSH 287



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%)

Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449
           +KK+          + +  R SG   P  A        D + + V        +E  + +
Sbjct: 34  RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 90

Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506
           K + R    V   + +++  S +     E   P S  PS   G S     +N + S    
Sbjct: 91  KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 148

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565
              Q++   +P  P+P   E         ++ +  PP +    G+    ++ P  +  + 
Sbjct: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 208

Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622
              P P     P    P++ + P+  Q    PV     P    +Q + A   +  P+P P
Sbjct: 209 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 262

Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682
           P     PS       P  P +    P  GS  +    S    P  G  G P         
Sbjct: 263 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 299

Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742
               P   +A P     +Q PGP +P  LP    + +         A     + LP    
Sbjct: 300 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 351

Query: 743 GVEMDETDRE 752
            ++  +  RE
Sbjct: 352 ALQSQQPPRE 361



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%)

Query: 269 EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328
           E D+GL  +    + RS  + S+                 G    PA+P  R  + I E 
Sbjct: 7   EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 51

Query: 329 LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388
           +RS                 G     A      D   E +  +  KV   A +       
Sbjct: 52  IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 89

Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443
           LK  ++++ ++A++  ++A+R S  +       RP      E    +   VN   SS  +
Sbjct: 90  LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148

Query: 444 EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495
           +I    + +  +  S  +   DS+  +++   + +P +L         PS+    + Q P
Sbjct: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 208

Query: 496 DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536
                 S   +   GSP     QAP +P  P A +                  PHPP   
Sbjct: 209 TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 264

Query: 537 VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594
              P P + P  G   + +   +    +  + P PG  S +     + P   Q   LP  
Sbjct: 265 HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 323

Query: 595 VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640
            S G  P              Q    Q +   +      P PPA L +P  K     P  
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 380

Query: 641 PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696
           P   L  P+         G    S  +   P  A  P +           P   +  PQ 
Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 440

Query: 697 Q----ESVQPPGPARPQSLP 712
           Q       QPPG  + Q+LP
Sbjct: 441 QPLPSSPAQPPGLTQSQNLP 460


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%)

Query: 60   SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116
            + S+   S+ S + P   G   P    L A  L      P   G  P +S G  P  T P
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889

Query: 117  GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176
              A+P      H+ L  P +       QP    P  P+    P H    PTTP    PA 
Sbjct: 890  AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 941

Query: 177  ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
                P A    PH  GP   S   +   P    P       HP S H       PL   P
Sbjct: 942  ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 992

Query: 237  SSQPLPSTHRDP 248
             SQPLPS+   P
Sbjct: 993  QSQPLPSSPAQP 1004



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%)

Query: 45   SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95
            S  S+S  D+  S        + S+S S P    N  D D S+    L A      +   
Sbjct: 687  SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 746

Query: 96   NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148
             +P  S A PG+  L +P PT    A P       S     P +PT      H  Q  +L
Sbjct: 747  VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806

Query: 149  IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172
             P  P S   PPHP     L P T     P+AP                           
Sbjct: 807  HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866

Query: 173  -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205
                    P QAS+      T+P    P  S  LP++                    +MP
Sbjct: 867  GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926

Query: 206  LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253
             +K PP  P      P +     H SGP        L PPP+ +PL   STH  P     
Sbjct: 927  HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986

Query: 254  KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294
                   +  LP       GL + ++     +S   +  HQ
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%)

Query: 98   PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135
            P +  AMP   +  PPT P    P  + H+H             ++L  PP         
Sbjct: 919  PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 136  -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178
             + P   HP P  L+P     PSS   PP       LP  PA          AP P  A 
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 179  ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238
               V     P TP  C     PSTS P      P +    PCS   G   SG  +   SS
Sbjct: 1037 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 1085

Query: 239  QPLPS 243
             PLP+
Sbjct: 1086 CPLPT 1090



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%)

Query: 24  MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83
           + ED R +GR    A S S    K+++    +      +SS   S+       + D + +
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 84  SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117
              S+ K      S P+S     G S  S                      P+IP     
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 721

Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175
           E+   S   Q      PP   +PTG  P P+S  P      G+P  P   PT  A   P 
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 775

Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234
           Q S     A   P  P  P   +H+        + PP      HP              P
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 822

Query: 235 PPSSQPLPSTHRDPGCKGH 253
            P  QPL  +   P    H
Sbjct: 823 HPPLQPLTGSAGQPSAPSH 841



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%)

Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449
           +KK+          + +  R SG   P  A        D + + V        +E  + +
Sbjct: 588 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 644

Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506
           K + R    V   + +++  S +     E   P S  PS   G S     +N + S    
Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 702

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565
              Q++   +P  P+P   E         ++ +  PP +    G+    ++ P  +  + 
Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622
              P P     P    P++ + P+  Q    PV     P    +Q + A   +  P+P P
Sbjct: 763 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 816

Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682
           P     PS       P  P +    P  GS  +    S    P  G  G P         
Sbjct: 817 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 853

Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742
               P   +A P     +Q PGP +P  LP    + +         A     + LP    
Sbjct: 854 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905

Query: 743 GVEMDETDRE 752
            ++  +  RE
Sbjct: 906 ALQSQQPPRE 915



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%)

Query: 269  EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328
            E D+GL  +    + RS  + S+                 G    PA+P  R  + I E 
Sbjct: 561  EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 605

Query: 329  LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388
            +RS                 G     A      D   E +  +  KV   A +       
Sbjct: 606  IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 643

Query: 389  LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443
            LK  ++++ ++A++  ++A+R S  +       RP      E    +   VN   SS  +
Sbjct: 644  LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 702

Query: 444  EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495
            +I    + +  +  S  +   DS+  +++   + +P +L         PS+    + Q P
Sbjct: 703  DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 496  DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536
                  S   +   GSP     QAP +P  P A +                  PHPP   
Sbjct: 763  TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 818

Query: 537  VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594
               P P + P  G   + +   +    +  + P PG  S +     + P   Q   LP  
Sbjct: 819  HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 877

Query: 595  VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640
             S G  P              Q    Q +   +      P PPA L +P  K     P  
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 934

Query: 641  PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696
            P   L  P+         G    S  +   P  A  P +           P   +  PQ 
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994

Query: 697  Q----ESVQPPGPARPQSLP 712
            Q       QPPG  + Q+LP
Sbjct: 995  QPLPSSPAQPPGLTQSQNLP 1014


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%)

Query: 60   SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116
            + S+   S+ S + P   G   P    L A  L      P   G  P +S G  P  T P
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889

Query: 117  GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176
              A+P      H+ L  P +       QP    P  P+    P H    PTTP    PA 
Sbjct: 890  AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 941

Query: 177  ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236
                P A    PH  GP   S   +   P    P       HP S H       PL   P
Sbjct: 942  ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 992

Query: 237  SSQPLPSTHRDP 248
             SQPLPS+   P
Sbjct: 993  QSQPLPSSPAQP 1004



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%)

Query: 45   SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95
            S  S+S  D+  S        + S+S S P    N  D D S+    L A      +   
Sbjct: 687  SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 746

Query: 96   NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148
             +P  S A PG+  L +P PT    A P       S     P +PT      H  Q  +L
Sbjct: 747  VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806

Query: 149  IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172
             P  P S   PPHP     L P T     P+AP                           
Sbjct: 807  HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866

Query: 173  -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205
                    P QAS+      T+P    P  S  LP++                    +MP
Sbjct: 867  GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926

Query: 206  LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253
             +K PP  P      P +     H SGP        L PPP+ +PL   STH  P     
Sbjct: 927  HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986

Query: 254  KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294
                   +  LP       GL + ++     +S   +  HQ
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%)

Query: 98   PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135
            P +  AMP   +  PPT P    P  + H+H             ++L  PP         
Sbjct: 919  PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 136  -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178
             + P   HP P  L+P     PSS   PP       LP  PA          AP P  A 
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 179  ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238
               V     P TP  C     PSTS P      P +    PCS   G   SG  +   SS
Sbjct: 1037 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 1085

Query: 239  QPLPS 243
             PLP+
Sbjct: 1086 CPLPT 1090



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%)

Query: 24  MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83
           + ED R +GR    A S S    K+++    +      +SS   S+       + D + +
Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 84  SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117
              S+ K      S P+S     G S  S                      P+IP     
Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 721

Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175
           E+   S   Q      PP   +PTG  P P+S  P      G+P  P   PT  A   P 
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 775

Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234
           Q S     A   P  P  P   +H+        + PP      HP              P
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 822

Query: 235 PPSSQPLPSTHRDPGCKGH 253
            P  QPL  +   P    H
Sbjct: 823 HPPLQPLTGSAGQPSAPSH 841



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%)

Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449
           +KK+          + +  R SG   P  A        D + + V        +E  + +
Sbjct: 588 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 644

Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506
           K + R    V   + +++  S +     E   P S  PS   G S     +N + S    
Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 702

Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565
              Q++   +P  P+P   E         ++ +  PP +    G+    ++ P  +  + 
Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622
              P P     P    P++ + P+  Q    PV     P    +Q + A   +  P+P P
Sbjct: 763 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 816

Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682
           P     PS       P  P +    P  GS  +    S    P  G  G P         
Sbjct: 817 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 853

Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742
               P   +A P     +Q PGP +P  LP    + +         A     + LP    
Sbjct: 854 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905

Query: 743 GVEMDETDRE 752
            ++  +  RE
Sbjct: 906 ALQSQQPPRE 915



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%)

Query: 269  EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328
            E D+GL  +    + RS  + S+                 G    PA+P  R  + I E 
Sbjct: 561  EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 605

Query: 329  LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388
            +RS                 G     A      D   E +  +  KV   A +       
Sbjct: 606  IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 643

Query: 389  LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443
            LK  ++++ ++A++  ++A+R S  +       RP      E    +   VN   SS  +
Sbjct: 644  LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 702

Query: 444  EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495
            +I    + +  +  S  +   DS+  +++   + +P +L         PS+    + Q P
Sbjct: 703  DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 496  DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536
                  S   +   GSP     QAP +P  P A +                  PHPP   
Sbjct: 763  TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 818

Query: 537  VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594
               P P + P  G   + +   +    +  + P PG  S +     + P   Q   LP  
Sbjct: 819  HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 877

Query: 595  VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640
             S G  P              Q    Q +   +      P PPA L +P  K     P  
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 934

Query: 641  PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696
            P   L  P+         G    S  +   P  A  P +           P   +  PQ 
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994

Query: 697  Q----ESVQPPGPARPQSLP 712
            Q       QPPG  + Q+LP
Sbjct: 995  QPLPSSPAQPPGLTQSQNLP 1014


>gi|13128980 proline rich 14 [Homo sapiens]
          Length = 585

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 62/211 (29%), Positives = 83/211 (39%), Gaps = 24/211 (11%)

Query: 98  PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFG 157
           P    A+P   L SPPT P  A  +      S L  P  SP G  P   S + S   SF 
Sbjct: 203 PFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS-VRSKLESFA 261

Query: 158 S---PPHPHLLPTTPAAPFP-------AQASECPVAAATAPHTP-GPCQSSHLPSTSMPL 206
                P+    P  P+ P         ++A +   A  TA  +P  P +       + P 
Sbjct: 262 DIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPA 321

Query: 207 LKMPPPFSGCSHPCS--GHCG-GHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQ 263
           L +P P  G S+ C   G  G G C+ P  PP  S+P P  H   G           A  
Sbjct: 322 L-LPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGG------GEMARAPP 374

Query: 264 LPQPCEADE--GLGEEEDSSSERSSCTSSST 292
            P+PC   E   LG    S S  +SC+S+++
Sbjct: 375 PPRPCLRKEVFPLGGVGASPSLTTSCSSTAS 405


>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
           sapiens]
          Length = 1833

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 60/190 (31%), Positives = 73/190 (38%), Gaps = 35/190 (18%)

Query: 510 QNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTP 569
           Q+   Q P +P PP  E  G    W    GPPP   P  G VR  N+        W   P
Sbjct: 819 QHQQQQPPQQPPPPQPEASGS---WG---GPPP---PPPGNVRPSNSS-------WSSGP 862

Query: 570 KPGYPSSEEPSSKEVP-----SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRP 622
           +P  P  EEPS  E P     S K ++ +  S+ G P     K      K S+  PAPR 
Sbjct: 863 QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922

Query: 623 PASLEVP--SAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKG 680
           P +L  P  S    V     P      P  G+ A  GE +  S   PGW G         
Sbjct: 923 P-NLPTPMTSKSASVWSKSTP----PAPDNGTSA-WGEPNESS---PGW-GEMDDTGAST 972

Query: 681 SSWRNWPGEA 690
           + W N P  A
Sbjct: 973 TGWGNTPANA 982



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 28/156 (17%)

Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ--------------AK 612
           + P  G+ S +    +EV   K    E  SS  KP  G  +G Q              A 
Sbjct: 736 RQPNQGWSSGKNGWGEEVDQTKNSNWE--SSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793

Query: 613 KSEASPAPRPPASLEV---PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGW 669
           K       R PA  E    P++  +    +QP +    P+         GS G  P P  
Sbjct: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQ-----PEASGSWGGPPPP-- 846

Query: 670 AGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705
              P   +   SSW + P  A  + +E    + P P
Sbjct: 847 --PPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 55/163 (33%), Positives = 68/163 (41%), Gaps = 46/163 (28%)

Query: 95  WNSPHSSGAMPGSSL--GSP-----PTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPAS 147
           W +  +S + PG+ L  G+P     P  PG  FP+         T+PP  P+   P P S
Sbjct: 797 WTAFSTSSSSPGTPLSPGNPFSPGTPISPGPIFPI---------TSPPCHPS---PSPFS 844

Query: 148 LIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLL 207
            I S  SS    P PH  PT+   PF +   E PV  +        C  S LP+TS    
Sbjct: 845 PISSQVSS---NPSPH--PTSSPLPFSSSTPEFPVPLS-------QCPWSSLPTTS---- 888

Query: 208 KMPPPFS-GCSHPCSGHCGGHCSGPLLPP-PSSQPLPSTHRDP 248
             PP FS  CS           S P  PP PS+   PST   P
Sbjct: 889 --PPTFSPTCSQVT-------LSSPFFPPCPSTSSFPSTTAAP 922



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 50/194 (25%), Positives = 68/194 (35%), Gaps = 24/194 (12%)

Query: 50   SCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWD------PSSF---LSAHKLSGLWNSPHS 100
            S     H +SS    SSS+     P +   W       P +F    S   LS  +  P  
Sbjct: 851  SSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCP 910

Query: 101  SGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAP-PNSPTGHHPQPASLIPSHP------ 153
            S +   S+  +P      AF ++       L +P P   +   P P S +PS P      
Sbjct: 911  STSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVA 970

Query: 154  SSFGSPPHPHLLPTT------PAAPFPAQASECPVAAATAPHTPGPCQ--SSHLPSTSMP 205
                  P PH           PA P P +A   P++    P   G  Q  SS  P+  +P
Sbjct: 971  PGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLP 1030

Query: 206  LLKMPPPFSGCSHP 219
            L    P  SG   P
Sbjct: 1031 LQPTSPTLSGSPKP 1044



 Score = 36.6 bits (83), Expect = 0.093
 Identities = 78/295 (26%), Positives = 105/295 (35%), Gaps = 43/295 (14%)

Query: 410  VSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGF 469
            +S   EP P     +  PD   + + S  S    E ++    S  +S     LS   N F
Sbjct: 762  LSPQEEPAPLPALPVPLPDPSNEELQSSTSL---EHRSWTAFSTSSSSPGTPLS-PGNPF 817

Query: 470  SKEGAAEPEPQ---SLPPSNLSGS--SEQQPDINLDLSPLTLGSPQNHTLQAPGEPAP-- 522
            S      P P    + PP + S S  S     ++ + SP    SP   +   P  P P  
Sbjct: 818  SPGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLS 877

Query: 523  --PWAEMRGPHPPW-------TEVRGP--PPGIVPENGLVRRLNTVPNLS-------RVI 564
              PW+ +    PP          +  P  PP   P           P LS        V+
Sbjct: 878  QCPWSSLPTTSPPTFSPTCSQVTLSSPFFPP--CPSTSSFPSTTAAPLLSLASAFSLAVM 935

Query: 565  WVK----TPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620
             V     +P PG   S+ P +   P     LP PV+ GG  Q+     +   +SEASP P
Sbjct: 936  TVAQSLLSPSPGL-LSQSPPAPPSPLPSLPLPPPVAPGG--QESPSPHTAEVESEASPPP 992

Query: 621  RPPASLEVPSAKGQVAG-PKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPK 674
              P   E   A     G P+  GR     +V S  E  E        P  +GSPK
Sbjct: 993  ARPLPGEARLAPISEEGKPQLVGRF----QVTSSKEPAEPLPLQPTSPTLSGSPK 1043



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 37/165 (22%), Positives = 65/165 (39%), Gaps = 24/165 (14%)

Query: 592 PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAK---GQVAGPKQPGRVLELP 648
           P P+ + G+P+ G     +A++      PRP +S     +    G ++    P      P
Sbjct: 25  PPPLGTAGQPRLGPPP-RRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSWSLPASPAPDP 83

Query: 649 KVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWP----GEAKARPQEQESVQPPG 704
                    +    + PGP  +  P +++    +W         E  ARP+  +S   PG
Sbjct: 84  P--------DPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAAEDSARPELPDSAVGPG 135

Query: 705 PARPQSLPQGKGRSRRSRNKQEKP-------ASSLDDVFLPKDMD 742
              P  +P+     RR R ++EK        A+S D  +L  D++
Sbjct: 136 SREPLRVPEAVALERR-REQEEKEDMETQAVATSPDGRYLKFDIE 179



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 36/140 (25%), Positives = 47/140 (33%), Gaps = 32/140 (22%)

Query: 574  PSSEEPSSKEVPSCKQELP-----EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEV 628
            P + E  S+  P   + LP      P+S  GKPQ   R    + K  A P P  P S   
Sbjct: 979  PHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQPTS--- 1035

Query: 629  PSAKGQV-------------------AGPKQPGRVLELPKVGSCAEAG---EGSRGSRPG 666
            P+  G                      GP+    + E  +      AG   EG  G  P 
Sbjct: 1036 PTLSGSPKPSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGLGAGVEEEGDDGKEPQ 1095

Query: 667  PGWAGSPKTEKEKGSSWRNW 686
             G  GSP+        W N+
Sbjct: 1096 VG--GSPQPLSHPSPVWMNY 1113


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 79/348 (22%), Positives = 132/348 (37%), Gaps = 55/348 (15%)

Query: 369 NSTEPKVPN-SARAAKRARHKLKKKEKEKAQLAAEALKQANR-------VSGSREPRPAR 420
           NS E   P  SA  A    ++  +  +E+ + A + L +  R       + GS+     +
Sbjct: 591 NSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650

Query: 421 ERLLEWPDRE-LDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEP-- 477
                +  R+ LD +      ++++ +N  +   +A  +           S+E A  P  
Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAA----------SEEAAFPPVV 700

Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT-E 536
           E + +  S +SG+ E+  +   +       S    ++ +P   A       GP PP T  
Sbjct: 701 EDEEMEASGVSGNEEEMVE---EAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLG 757

Query: 537 VRGPPPG--IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEP 594
             GPPPG    P   +       P  S      TP P  PS   P    VP  K+E  E 
Sbjct: 758 ADGPPPGPPTPPPEDIPAPTEPTP-ASEATGAPTPPPAPPSPSAPPPV-VP--KEEKEEE 813

Query: 595 VSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLEL---PKVG 651
            ++    ++G+ Q             +PPA+ E+    G+   P +     E    P  G
Sbjct: 814 TAAAPPVEEGEEQ-------------KPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKG 860

Query: 652 SCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699
             AEA E +          G+ K EK++G S R    ++   PQ+ +S
Sbjct: 861 KDAEAAEATA--------EGALKAEKKEGGSGRATTAKSSGAPQDSDS 900



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 68/291 (23%), Positives = 110/291 (37%), Gaps = 47/291 (16%)

Query: 16   VCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSC-GDDSHSSSSSSSSSSSSSSSSCP 74
            V   C +  EE   + G++   A + +  + K++   G    ++++ SS +   S SS  
Sbjct: 845  VKSECTEEAEEGPAK-GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSAT 903

Query: 75   GNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPT--IPGEAFPVSEHHQHSDLT 132
             ++ + D +     ++L     SP  S   P    G P     P +   + +  Q +   
Sbjct: 904  CSADEVDEAEGGDKNRLL----SPRPSLLTP---TGDPRANASPQKPLDLKQLKQRAAAI 956

Query: 133  APPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLP----------------TTPAAPFPAQ 176
             P      H P      P+ P+    PP  +L P                 +PA P   +
Sbjct: 957  PPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKE 1016

Query: 177  ASE---CPVAAATAPHTPG--PCQSSHLPSTSMP--LLKMPPPF---SGCSHPCSGH--- 223
            A +    P  AA A   PG  PC +S LP    P  ++K  P     S  S+   GH   
Sbjct: 1017 AEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1076

Query: 224  CGGH-CSGPLLPPP----SSQPLPSTHRDPGCKGHKFA--HSGLACQLPQP 267
             G H  + P+LP P    +  PL S+ + P     +      G++ QL  P
Sbjct: 1077 LGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVP 1127



 Score = 33.5 bits (75), Expect = 0.79
 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 17/111 (15%)

Query: 112 PPTIPGEAFPVS-------EHHQHSDLTAPPNSPTGHHPQPASLI--------PSHPSSF 156
           PP +  E    S       E  + ++ T   +S T   P P +          P  P++ 
Sbjct: 697 PPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATL 756

Query: 157 GSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLL 207
           G+   P   PT P    PA     P + AT   TP P   S  PS   P++
Sbjct: 757 GADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS--PSAPPPVV 805



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 35/168 (20%), Positives = 59/168 (35%), Gaps = 28/168 (16%)

Query: 16  VCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSS--SSSSSC 73
           + Q  +  ME++     ++     + S  +       D+   +S  S +       + + 
Sbjct: 665 ILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEAT 724

Query: 74  PGNSGDWD--PSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDL 131
             NS D +  PS    A K +G       +G  P ++LG+    PG              
Sbjct: 725 VNNSSDTESIPSPHTEAAKDTG------QNGPKPPATLGADGPPPG-------------- 764

Query: 132 TAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASE 179
             PP  P    P P    P+  ++    P P   P +P+AP P    E
Sbjct: 765 --PPTPPPEDIPAPTEPTPASEATGAPTPPP--APPSPSAPPPVVPKE 808


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 87/392 (22%), Positives = 143/392 (36%), Gaps = 61/392 (15%)

Query: 372 EPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDREL 431
           E K P  A++ ++A+  +K++ K  A+  +   ++A   +  + P  A+    E    E 
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE----EA 646

Query: 432 DRVNSFLSSRLQEIKNT--VKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSG 489
                  S   +E K+    K  ++A     E +       K  A  PE    P    + 
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP---VKAEAKSPEKAKSPVKEEAK 703

Query: 490 SSEQ--QPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPE 547
           S E+   P      SP    SP     + P +   P  E         E + P     PE
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE---------EAKSPEKAKSPE 754

Query: 548 NGLVRRLNTVPNLSRVIWVKTPKPGYPSSEE---PSSKEVPSCKQELPEPVSSGGKPQKG 604
                        ++ + VK+P+   P+ EE   P+ K     K  + E V S   P+K 
Sbjct: 755 K------------AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS---PEKA 799

Query: 605 KRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSR 664
           K   S  K+   +P    P   EV S   +   P++  +V E PK     +A        
Sbjct: 800 K---SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV-KVKEPPKKAEEEKA-------- 847

Query: 665 PGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNK 724
                  +PKTE++K S     P +   +P+ +E  +P      +S  + K      + K
Sbjct: 848 -----PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902

Query: 725 -----QEKPAS-SLDDVFLPKDMDGVEMDETD 750
                +E PA   + +   PK+   V   E D
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 86/388 (22%), Positives = 140/388 (36%), Gaps = 70/388 (18%)

Query: 372  EPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDREL 431
            E K P  A++  +A  + K  EK K+ + AEA       S  +E   + E+    P +E 
Sbjct: 659  EAKSPEKAKSPVKA--EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS-PVKEE 715

Query: 432  DRVNSFLSSRLQE-----------IKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480
             +      S ++E           +K   K   +A       ++D      +  A+ E +
Sbjct: 716  AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775

Query: 481  SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGP-----HPPWT 535
            S  P++      + P      SP    SP     +AP +  P   E++ P      P   
Sbjct: 776  S--PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833

Query: 536  EVRGPPPGIVPENGLVRRLNTVPNLSRVIWV---KTPKPGYPSSEEPS------------ 580
            +V+ PP     E             S+       + PKP     +EP+            
Sbjct: 834  KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 581  ------SKEVPSCKQELPE--PVSSGGKPQK----GKRQGSQAKKSEAS-PAPRPPASLE 627
                   K+VP+ ++E P    V    KP++     K++   AK  E S PA +  A+ E
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953

Query: 628  VPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWP 687
                K + A  K+P    E PK  + A+  + +    P       PK EK + SS     
Sbjct: 954  KKDTKEEKA--KKPE---EKPKTEAKAKEDDKTLSKEP-----SKPKAEKAEKSS----- 998

Query: 688  GEAKARPQEQESVQPPGPARPQSLPQGK 715
                    +Q+  +PP  A      +GK
Sbjct: 999  ------STDQKDSKPPEKATEDKAAKGK 1020



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 45/202 (22%), Positives = 83/202 (41%), Gaps = 13/202 (6%)

Query: 539 GPPPGIVPENGLVRRLNTVPNLSRVIWVKTP---KPGYPSSEEPSSKEVPSCKQELPEPV 595
           GP P  +PE      L  +P++S  I VK+    K    S +E    E  + + ++ E V
Sbjct: 416 GPIPFSLPEG-----LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470

Query: 596 SSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAE 655
           +   + +  + +G + +  E   A       + P A+ + A P++  +     +  S AE
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE-EAASPEKEAKSPVKEEAKSPAE 529

Query: 656 AGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP---PGPARPQSLP 712
           A    +     P    SP+  K         P EAK+ P+++E+  P     P + +S  
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAEVKSPEKAKSPA 588

Query: 713 QGKGRSRRSRNKQEKPASSLDD 734
           + + +S       EK  S + +
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKE 610


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 64/241 (26%), Positives = 83/241 (34%), Gaps = 86/241 (35%)

Query: 487 LSGSSEQQPDINLDLSP-LTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPP--G 543
           LS +     D++ + SP L  G+PQ  + Q   +P       +GP PP  + +GPPP  G
Sbjct: 13  LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKP-------QGPPPPPGKPQGPPPQGG 65

Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPS-----SKEVPSCKQELPEPVSSG 598
             P+                     P PG P    P      S   P  K + P P   G
Sbjct: 66  NKPQG-------------------PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP--QG 104

Query: 599 GKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGE 658
           GKPQ    QG    +S  SP  +P              GP Q                 E
Sbjct: 105 GKPQGPPAQGGSKSQSARSPPGKP-------------QGPPQQ----------------E 135

Query: 659 GSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRS 718
           G+    P P   G+P+                  +PQ   + QP GP RP   PQG   S
Sbjct: 136 GNNPQGPPPPAGGNPQ------------------QPQAPPAGQPQGPPRP---PQGGRPS 174

Query: 719 R 719
           R
Sbjct: 175 R 175



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 13/148 (8%)

Query: 97  SPHSSGAMPGSSLGSPPTIPGEAF-PVSEHHQHSDLTAPPNSPTGHHPQ-PASLIPSHPS 154
           +P       G+    PP  PG+   P  +         PP  P G  PQ   S  P  P 
Sbjct: 35  NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94

Query: 155 SFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTSMPLLKMPPP 212
             G P  P      P  P PAQ      +A + P  P   P Q  + P         PPP
Sbjct: 95  --GKPQGPPPQGGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP------PPP 145

Query: 213 FSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
             G          G   GP  PP   +P
Sbjct: 146 AGGNPQQPQAPPAGQPQGPPRPPQGGRP 173



 Score = 33.5 bits (75), Expect = 0.79
 Identities = 39/146 (26%), Positives = 52/146 (35%), Gaps = 34/146 (23%)

Query: 586 SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGR 643
           S  Q L E VS    P    G  QG   +       P PP         G+  GP   G 
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPP--------GKPQGPPPQG- 64

Query: 644 VLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPP 703
                        G   +G  P PG    P  + +K  S R+ PG+ +          PP
Sbjct: 65  -------------GNKPQGPPP-PGKPQGPPPQGDKSRSPRSPPGKPQG--------PPP 102

Query: 704 GPARPQSLP-QGKGRSRRSRNKQEKP 728
              +PQ  P QG  +S+ +R+   KP
Sbjct: 103 QGGKPQGPPAQGGSKSQSARSPPGKP 128


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 71/276 (25%), Positives = 101/276 (36%), Gaps = 52/276 (18%)

Query: 487 LSGSSEQQPDINLDLSPLTL-----------GSPQNHTLQAPGEPA--PPWA--EMRGPH 531
           LS +     D++ + SP  +           G+    T   PG+P   PP    + +GP 
Sbjct: 13  LSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPP 72

Query: 532 PPWTEVRGPPP-------GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP---SS 581
           P   +  GPPP       G  P  G  +     P          P+PG P    P   + 
Sbjct: 73  PRPGKPEGPPPQGGNQSQGPPPRPG--KPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 130

Query: 582 KEVPSCKQELPE-PVSSGGK------PQKGKRQGSQAKKSEASPAPRP-PASLEVPSAKG 633
            + P  +   PE P   GG       P+ GK +G   +    S  P P P   E P  +G
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190

Query: 634 --QVAGPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690
             Q  GP  +PG+    P  G     G  S+G  P PG    P+    +G +    P   
Sbjct: 191 GNQSQGPPPRPGKPEGPPPQG-----GNQSQGPPPRPG---KPEGPPSQGGNKPQGPPPH 242

Query: 691 KARPQ------EQESVQPPGPARPQSLPQGKGRSRR 720
             +PQ        +  +PP P RPQ  P   G  ++
Sbjct: 243 PGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQ 278



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 40/169 (23%), Positives = 55/169 (32%), Gaps = 34/169 (20%)

Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQN-----HTLQAPGEPAPPWAEMRGPHP 532
           +P+  PP   + S    P       P   G  Q+     H  +  G P     + +GP P
Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP 199

Query: 533 PWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELP 592
              +  GPP    P+ G         N S+      P+PG P          P       
Sbjct: 200 RPGKPEGPP----PQGG---------NQSQ---GPPPRPGKPEGPPSQGGNKP------- 236

Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641
                G  P  GK QG   ++      P PP   + P   G    P+QP
Sbjct: 237 ----QGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPG--GNPQQP 279


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 25/191 (13%)

Query: 60  SSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEA 119
           S  S     S  S P  S  + P   L    LS    SP      P  +L +P + P EA
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSP---LEESPLSPPEESP------PSPALETPLSPPPEA 542

Query: 120 FPVSEHHQHSDLTAPPNS-PTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQAS 178
            P+S   + S L+ PP   PT   P+ + L P    S  SPP P   P +P    P +AS
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-PEESPMSP----PPEAS 597

Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPS- 237
                   +P +P P +S   P      L  PP  S  S P           P+ PPP  
Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE-------ESPMSPPPEV 650

Query: 238 --SQPLPSTHR 246
               PLP   R
Sbjct: 651 SRLSPLPVVSR 661



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/262 (24%), Positives = 88/262 (33%), Gaps = 36/262 (13%)

Query: 471 KEGAAEPEPQSLPPSNLSGS-------SEQQPDINLDLSPLTLGSP-----QNHTLQAPG 518
           +E    P P+S P S L  S       S   P +   LSP    SP     +   L  P 
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558

Query: 519 EPAP----PWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYP 574
           E  P    P A    P PP      PPP   P       ++  P  SR+       P  P
Sbjct: 559 EELPTSPPPEASRLSP-PPEESPMSPPPEESP-------MSPPPEASRLFPPFEESPLSP 610

Query: 575 SSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQ 634
             EE      P   +  P P  S   P          ++S  SP P       +P    +
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSP--------PPEESPMSPPPEVSRLSPLP-VVSR 661

Query: 635 VAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARP 694
           ++ P +   +   P+    +   E SR S P      SP  E    S     P ++    
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSLMSL 718

Query: 695 QEQESVQPPGPARPQSLPQGKG 716
             +ES   P P  PQ  P+ +G
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEG 740



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 44/150 (29%)

Query: 116 PGEAFPVSEHHQHSDLTAPPNS-------------PTGHHPQPASLIPSHPSSFGSP--- 159
           P E  P+S   + S L+ PP S             P    P PA   P  P    SP   
Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547

Query: 160 --------PHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPP 211
                   P P  LPT+P    P +AS        +P +P P +S   P       ++ P
Sbjct: 548 PFEESPLSPPPEELPTSP----PPEASRLSPPPEESPMSPPPEESPMSPPPEAS--RLFP 601

Query: 212 PFSGCSHPCSGHCGGHCSGPLLPPPSSQPL 241
           PF                 PL PPP   PL
Sbjct: 602 PFE--------------ESPLSPPPEESPL 617



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 60/221 (27%), Positives = 73/221 (33%), Gaps = 61/221 (27%)

Query: 101  SGAMPGSS------LGSPPTIPGE-----------AFPVSEHHQHSDLTAPPN-SPTGHH 142
            +G++PG        L  PP +P +           A+P+      +  T PP  SPTG  
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206

Query: 143  PQPASLIPSHPSSFGSPPHPHLLPT-----TPAAPFPAQASECP-VAAATAPHTPGPCQS 196
             QP  L  S     G P   H  P       P+ P P     CP +     P +PG    
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266

Query: 197  SHLPSTSMPLLKMPPPFS-------------GCSHPCSG----------HCGGHCSGPLL 233
                  S PLL  PPPF              G S P  G            G H  G  L
Sbjct: 2267 ----KASEPLLS-PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321

Query: 234  PPPSSQPLPSTHR----DPGCKGHKFAHSGLACQLPQPCEA 270
              P     P T R    +P   G      GL  Q P P +A
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPG-----LGLRPQEPPPAQA 2357



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 71/290 (24%), Positives = 101/290 (34%), Gaps = 38/290 (13%)

Query: 447 NTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQ-QPDINLDLS--- 502
           +T  D   A +  C+        +     EP P       L  +  Q +P +   L+   
Sbjct: 379 DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEM 438

Query: 503 PLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSR 562
           PL L  P+   L  P E +P         PP      PPP  +P + L   L    +LSR
Sbjct: 439 PL-LPPPEESPLSPPPEESPT------SPPPEASRLSPPPEELPASPLPEAL----HLSR 487

Query: 563 VIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622
            +      P  P  E P S          P P SS   P +   +   +   E+ P+P  
Sbjct: 488 PLEESPLSP--PPEESPLS----------PPPESSPFSPLE---ESPLSPPEESPPSPAL 532

Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682
              L  P     ++ P +   +   P+    +   E SR S P      SP  E+   S 
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592

Query: 683 WRNWPGEAKA--RPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730
               P EA     P E+  + PP    P S P     SR S   ++ P S
Sbjct: 593 ----PPEASRLFPPFEESPLSPPPEESPLSPP--PEASRLSPPPEDSPMS 636



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 50/169 (29%), Positives = 56/169 (33%), Gaps = 21/169 (12%)

Query: 98   PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNS----------PTGHHPQPAS 147
            P S  A+P  SL S P     A P S+    S LT  P S          P    P P S
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451

Query: 148  LIPSHPSSFG--SPPHPHLLPTTPAAPFPAQA---SECPVAAATAPHTPGPCQSSH--LP 200
              PS P S    +P H    P  P   F A +   +        A    GP    H  +P
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511

Query: 201  STSMPLLKMPP---PFSGCSHPCSGHCGGHCSGPLLPPPSSQP-LPSTH 245
            S   P     P    F G   P           P L PP  QP LP  H
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH 2560



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 63/261 (24%), Positives = 87/261 (33%), Gaps = 42/261 (16%)

Query: 5   VKNLLGEMPL--WVCQSCRKSME----EDERQTGREHAVAISLSHTSCKSQSCGDDSHSS 58
           +K  + E+P   W C++CR          E     E     SL H   K+Q  G    S 
Sbjct: 303 LKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQG-GQTIRSV 361

Query: 59  SSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP------------- 105
           +   +   S  S   PG++   +P +   A    G     H +   P             
Sbjct: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVA--CQGQPKGGHVTSMQPKEPGPLQCEAKPL 419

Query: 106 ---GSSLGSPPTIP-GEAFPVSEHHQHSDLTAPP-NSPTGHHPQPASLIPSHPSSFGSPP 160
              G  L      P  E  P+    + S L+ PP  SPT   P+ + L P  P    + P
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP-PEELPASP 478

Query: 161 HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPC 220
            P  L  +     P + S        +P +P P  S   P    PL    PP      P 
Sbjct: 479 LPEALHLSR----PLEESPLSPPPEESPLSPPPESSPFSPLEESPL---SPPEESPPSPA 531

Query: 221 SGHCGGHCSGPLLPPPSSQPL 241
                     PL PPP + PL
Sbjct: 532 -------LETPLSPPPEASPL 545



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 23/149 (15%)

Query: 111 SPPTIPGEAFPVSEHHQHSDLTAPP-NSPTGHHPQPASLIPSHPSSFGSP--------PH 161
           SP + P EA  +S   + S ++ PP  SP    P+ + L P    S  SP        P 
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674

Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS----------SHLPSTSMPLLKMPP 211
           P   PT+P    P +AS        +P +P P  S            LP    PLL +P 
Sbjct: 675 PEESPTSP----PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730

Query: 212 PFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240
               C      H       P L P   +P
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 53/202 (26%), Positives = 68/202 (33%), Gaps = 46/202 (22%)

Query: 91   LSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIP 150
            LS L    +  GA   S   SP   P    P+S          P  + T   P P  ++P
Sbjct: 951  LSPLGELEYPFGAKGDSDPESPLAAPILETPISP--------PPEANCTDPEPVPPMILP 1002

Query: 151  SHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLPSTSMPLLKM 209
              P S   P  P L+      P P Q S     +    ++ P  C    LP      L +
Sbjct: 1003 PSPGSPVGPASPILM-----EPLPPQCSPLLQHSLVPQNSPPSQCSPPALP------LSV 1051

Query: 210  PPPFS------GCS-----HPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHS 258
            P P S      G S     H            P L P ++ PLPS   D           
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD----------- 1100

Query: 259  GLACQLPQPCEADE---GLGEE 277
             L+C  P P  A +   GLGE+
Sbjct: 1101 -LSCPAPSPAPALDDFSGLGED 1121



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 55/211 (26%), Positives = 76/211 (36%), Gaps = 23/211 (10%)

Query: 514  LQAPGEPAPPWAEMRGPHPPWTEVRGPPPG--IVPENGLVRRLNTVPNLSRVIWVKTPKP 571
            L+ P  P PP A    P P    +  P PG  + P + ++      P  S ++       
Sbjct: 978  LETPISP-PPEANCTDPEPVPPMILPPSPGSPVGPASPILME-PLPPQCSPLLQHSL--- 1032

Query: 572  GYPSSEEPSSKEVPSCKQELPEPVSSGGK-----PQKGKRQGSQAKKSEAS-PAPRPPAS 625
              P +  PS    P+    +P P+S  GK      +    +    K SE   PA  P A+
Sbjct: 1033 -VPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091

Query: 626  LEVPSAKGQVAGPKQPGRVLELPKVGSCAE-----AGEGSRGSRPGPGWAGSPKTEKEKG 680
              +PS  G ++ P  P     L       E      G  + GS+P PG        + KG
Sbjct: 1092 SPLPSPMGDLSCP-APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKG 1150

Query: 681  SSWRNWPGE-AKARPQE--QESVQPPGPARP 708
            S     P E A   P E   E  Q  G   P
Sbjct: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 64/303 (21%), Positives = 101/303 (33%), Gaps = 81/303 (26%)

Query: 462  LSMDSNGFSKEGAAEPEPQSL---PPSNLSGSSEQQPDI----------NLDLSPLTLGS 508
            LS DS     +   +P+P SL   PP  L G  +QQ  +           L     +  S
Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128

Query: 509  PQNHTLQAPG-----EPAPPWAEMRGPHPPWTE--------VRGPPPGIVPENGL-VRRL 554
               H L  P      +P      + GP  P  E         + P PG V ++G  +  +
Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGV 4188

Query: 555  NTVPNLSRV------IWVKTPKPGYPSSEEPSSKEVPSCKQELPE--------------- 593
              +P + ++      +  K P+  + S ++    +    +++L +               
Sbjct: 4189 GIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGT 4248

Query: 594  ---PVSS--GGKPQKGKRQGSQA---KKSEASPAPRPPASLEVPS---AKGQVAGPKQPG 642
               P+    G +PQ G   G Q    ++  A P P+ P  L  P    + G V GP  P 
Sbjct: 4249 QTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP- 4307

Query: 643  RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP 702
                                  P P     PK   +  S     P EA+  P    + +P
Sbjct: 4308 ---------------------TPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346

Query: 703  PGP 705
             GP
Sbjct: 4347 QGP 4349



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 33/217 (15%)

Query: 476  EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535
            EP  Q+ P   L G    QP +           PQ   LQ  G    P    R P PP  
Sbjct: 4245 EPGTQTSPLQGLLGC---QPQLG------GFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295

Query: 536  EVRGP--------PPGIVPENGLVRRLNTVPNLSRVIWVK---------TPKPGYPSSEE 578
               GP        PP   P+    +R + +P+ S  +  +         TPKP  P+ E 
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEP--KRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP 4353

Query: 579  PSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGP 638
            P  +  P+  Q      S G  P       ++ +K E S     P  L+     GQV   
Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL--VPGHLD--QVNGQVVPE 4409

Query: 639  KQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKT 675
                 + + P+   CA   +  +    G    G+P T
Sbjct: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEP-IGAPGT 4445



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 29/104 (27%), Positives = 37/104 (35%), Gaps = 20/104 (19%)

Query: 112  PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA 171
            PPT     + VS       L+APP              P  PS    PP P  L  +PA+
Sbjct: 4888 PPTQHSYTYNVSNLDVRQ-LSAPP--------------PEEPSP---PPSP--LAPSPAS 4927

Query: 172  PFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSG 215
            P      E P      P  P P   +  P ++ P  +  PP  G
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEG 4971


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,428,004
Number of Sequences: 37866
Number of extensions: 2969692
Number of successful extensions: 29136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 270
Number of HSP's successfully gapped in prelim test: 1713
Number of HSP's that attempted gapping in prelim test: 17063
Number of HSP's gapped (non-prelim): 9687
length of query: 789
length of database: 18,247,518
effective HSP length: 110
effective length of query: 679
effective length of database: 14,082,258
effective search space: 9561853182
effective search space used: 9561853182
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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