BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154426272 hypothetical protein LOC54540 [Homo sapiens] (789 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154426272 hypothetical protein LOC54540 [Homo sapiens] 1644 0.0 gi|51873049 hypothetical protein LOC8603 [Homo sapiens] 278 2e-74 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 1e-11 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 1e-11 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 70 1e-11 gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 1e-10 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 64 7e-10 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 61 5e-09 gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 59 1e-08 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 58 4e-08 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 57 5e-08 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 1e-07 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 56 1e-07 gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 56 1e-07 gi|28559039 mediator complex subunit 1 [Homo sapiens] 55 3e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 55 3e-07 gi|150378539 piccolo isoform 1 [Homo sapiens] 55 3e-07 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 54 4e-07 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 54 4e-07 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 53 1e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06 gi|13128980 proline rich 14 [Homo sapiens] 53 1e-06 gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 53 1e-06 gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 52 2e-06 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 52 2e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 52 2e-06 gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre... 52 3e-06 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 52 3e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 51 4e-06 >gi|154426272 hypothetical protein LOC54540 [Homo sapiens] Length = 789 Score = 1644 bits (4258), Expect = 0.0 Identities = 789/789 (100%), Positives = 789/789 (100%) Query: 1 MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS 60 MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS Sbjct: 1 MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSS 60 Query: 61 SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120 SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF Sbjct: 61 SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120 Query: 121 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC 180 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC Sbjct: 121 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASEC 180 Query: 181 PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP Sbjct: 181 PVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 Query: 241 LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC 300 LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC Sbjct: 241 LPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFC 300 Query: 301 DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD 360 DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD Sbjct: 301 DCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRD 360 Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR Sbjct: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420 Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ Sbjct: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480 Query: 481 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP 540 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP Sbjct: 481 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGP 540 Query: 541 PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK 600 PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK Sbjct: 541 PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGK 600 Query: 601 PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS 660 PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS Sbjct: 601 PQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGS 660 Query: 661 RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR 720 RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR Sbjct: 661 RGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRR 720 Query: 721 SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL 780 SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL Sbjct: 721 SRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSL 780 Query: 781 KKTTPSTAQ 789 KKTTPSTAQ Sbjct: 781 KKTTPSTAQ 789 >gi|51873049 hypothetical protein LOC8603 [Homo sapiens] Length = 1224 Score = 278 bits (710), Expect = 2e-74 Identities = 246/745 (33%), Positives = 339/745 (45%), Gaps = 125/745 (16%) Query: 60 SSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGS-------- 111 S S +++ C N D +F+ A+K+ +S SS + +++ S Sbjct: 581 SDSKEKKNAAKKKCLYNFQD----AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVS 636 Query: 112 ---PPTIPGEAFPVS-EHHQHSDLTAPPNSPTGHHPQPASLIPS--HPSSFGSPPHPHLL 165 PP++ +S E H+HS AP NSPTG P PA L P+ P++ PHL Sbjct: 637 SKRPPSVGDVFHGISKEDHRHSAPAAPRNSPTGLAPLPA-LSPAALSPAALSPASTPHLA 695 Query: 166 PTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCG 225 A FP TA TPG + S C P Sbjct: 696 -NLAAPSFPK----------TATTTPGFVDTRK---------------SFCPAPLPPATD 729 Query: 226 GHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERS 285 G S P PS DP C+GH+ + PQ + DE +EDS SE S Sbjct: 730 GSISAP----------PSVCSDPDCEGHRCENGVYD---PQQDDGDESA--DEDSCSEHS 774 Query: 286 SCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGG 345 S TS+ST+Q++GK+CDCCYCEFFGH PPAAPTSRNY E+REKLR RLT+RKEE P K Sbjct: 775 SSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMD 834 Query: 346 TLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALK 405 + E VDHR V++LL+FINS+E K +S RAAKRARHK +K E EKA+L AEA Sbjct: 835 QIS--ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE-EKARLEAEARA 891 Query: 406 QANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKN----TVKDSIRASFSVCE 461 + + + R E E + E DR RLQE++ K R S + Sbjct: 892 REHLHLQEEQRRREEE---EDEEEEEDRFKEEF-QRLQELQKLRAVKKKKKERPSKDCPK 947 Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPA 521 L M + F + A E P S N S ++P+ + SP H + Sbjct: 948 LDMLTRNF--QAATESVPNSGNIHNGSLEQTEEPETSSH-------SPSRHMNHSE---- 994 Query: 522 PPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSS 581 P PG+ + ++T + K P Sbjct: 995 ------------------PRPGLGADGDAADPVDT----------RDSKFLLPKEVNGKQ 1026 Query: 582 KEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641 E S ++ + G QK RQ S+A A PP + E S A + Sbjct: 1027 HEPLSFFFDIMQHHKEGNGKQK-LRQTSKASSEPARRPTEPPKATEGQSKPR--AQTESK 1083 Query: 642 GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQ 701 +V++L + + K EK + P E + + Q++ + Sbjct: 1084 AKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPT-----PMEPTSPGEHQQNSK 1138 Query: 702 PPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPK--DMDGVEMDETDREVEYFKRF 759 PQ P+GK + + + K ++ +S+DDVFLPK D+D V+MDET+REVEYFKRF Sbjct: 1139 LVLAESPQ--PKGKNK-KNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRF 1195 Query: 760 CLDSAKQTRQKVAVNWTNFSLKKTT 784 CLDSA+QTRQ++++NW+NFSLKK T Sbjct: 1196 CLDSARQTRQRLSINWSNFSLKKAT 1220 Score = 36.2 bits (82), Expect = 0.12 Identities = 48/169 (28%), Positives = 63/169 (37%), Gaps = 33/169 (19%) Query: 53 DDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP 112 D+S SS+SSSSS + G S P A K G+ S S S SP Sbjct: 341 DESPQISSTSSSSSEADDEEADGESSGEPP----GAPKEDGVLGS--RSPRTEESKADSP 394 Query: 113 PTIPGEAFPVSEHHQHSDLTAPPNSPTGH--HPQPASLIPSHPSSFGSPP-HPHLLPTTP 169 P ++P + Q PN+ H + + L PS ++ PP H L P P Sbjct: 395 P----PSYPTQQAEQ------APNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPEKP 444 Query: 170 AAP----FPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFS 214 P +P P+ T PH P P P L PPF+ Sbjct: 445 THPALHLYPHIHGHVPL--HTVPHLPRP--------LIHPTLYATPPFT 483 Score = 32.3 bits (72), Expect = 1.8 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%) Query: 58 SSSSSSSSSSSSSSSCPGNSGDWDPSS---FLSAHKLSGLWNSPHSSGAMP-GSSLGSPP 113 S + S + S S P + P++ + + SGL S ++GA+P G SP Sbjct: 383 SPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPE 442 Query: 114 TIPGEAFPVSEH-HQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPA 170 A + H H H L P H P+P HP+ + +PP H PA Sbjct: 443 KPTHPALHLYPHIHGHVPLHTVP-----HLPRPLI----HPTLYATPPFTHSKALPPA 491 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 69.7 bits (169), Expect = 1e-11 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%) Query: 74 PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132 PG W L+ + SP S A P GS+LG P P FP S Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303 Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181 PP +P T P Q A P PS PP H+ P + P A +CP Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363 Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 ATAP +P Q+ T P +PPP P LPPP Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406 Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296 + PLP C K AH A P + L + + S ++ +S+ RD Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463 Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340 + E F H P AP S+ K RL ++ L Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518 Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400 P K T G+P E ++ + E + T P V + + + + E E A+L+ Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575 Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460 + A K+A GS P+P E +C Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601 Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517 E D + SK A PQS LP ++L + P I +P P +A Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656 Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575 PA P GP P GP + +G + T+P + + + Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716 Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630 E+P+S+EV + P G P + R +Q A+ S A P P EVP Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771 Query: 631 ------------------AKGQVAGPKQPGRVLELP 648 A+G AGP +P V E P Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807 Score = 41.6 bits (96), Expect = 0.003 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%) Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527 S A P P L PP S + P + P TL SP T PAPP A + Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224 Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579 P PP P P + P G+ + + V R P +E Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284 Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639 S P+ + L P S P R S EA APR K + A K Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333 Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699 P R L LP A + P P G K G+++++ E+ Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388 Query: 700 VQPPGPARPQSLP 712 PP P P P Sbjct: 389 TPPPAPPLPPPAP 401 Score = 37.4 bits (85), Expect = 0.055 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%) Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161 G L PP PG A +SE S L +PP+ T P P L P P S PP Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191 Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221 P L +P PHT S P + PP F + P + Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222 Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281 + P PPP P P P G + G + + E +S Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341 RS + + F PP P + ++E ++ RKEE Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330 Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401 K +P P+ R ++ + EP P +A A +L Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377 Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461 ++ QA+ +G+ P P L P L L + K + + Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428 Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514 S A +P+P P N + S+ Q + +L+ GS + Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560 PG P ++ +GP P E + PPG VPE L + P+L Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546 Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620 + P Y + P + V + EL +SS + +AK S S P Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591 Query: 621 RP 622 +P Sbjct: 592 KP 593 Score = 33.9 bits (76), Expect = 0.60 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%) Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566 G PQ+ + G P P P PP PPP + P V + P+ + Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208 Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610 TP P + + P P P + G R G Q Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268 Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670 A+ + ASP PR PA KG GP P L P+ S P Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321 Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723 +P+ E+ +K S P RP Q + +P P ++ R +S++ Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 724 KQEKPASS 731 + ++ A + Sbjct: 382 QADERAGT 389 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 69.7 bits (169), Expect = 1e-11 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%) Query: 74 PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132 PG W L+ + SP S A P GS+LG P P FP S Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303 Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181 PP +P T P Q A P PS PP H+ P + P A +CP Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363 Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 ATAP +P Q+ T P +PPP P LPPP Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406 Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296 + PLP C K AH A P + L + + S ++ +S+ RD Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463 Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340 + E F H P AP S+ K RL ++ L Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518 Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400 P K T G+P E ++ + E + T P V + + + + E E A+L+ Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575 Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460 + A K+A GS P+P E +C Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601 Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517 E D + SK A PQS LP ++L + P I +P P +A Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656 Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575 PA P GP P GP + +G + T+P + + + Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716 Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630 E+P+S+EV + P G P + R +Q A+ S A P P EVP Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771 Query: 631 ------------------AKGQVAGPKQPGRVLELP 648 A+G AGP +P V E P Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807 Score = 41.6 bits (96), Expect = 0.003 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%) Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527 S A P P L PP S + P + P TL SP T PAPP A + Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224 Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579 P PP P P + P G+ + + V R P +E Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284 Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639 S P+ + L P S P R S EA APR K + A K Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333 Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699 P R L LP A + P P G K G+++++ E+ Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388 Query: 700 VQPPGPARPQSLP 712 PP P P P Sbjct: 389 TPPPAPPLPPPAP 401 Score = 37.4 bits (85), Expect = 0.055 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%) Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161 G L PP PG A +SE S L +PP+ T P P L P P S PP Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191 Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221 P L +P PHT S P + PP F + P + Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222 Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281 + P PPP P P P G + G + + E +S Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341 RS + + F PP P + ++E ++ RKEE Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330 Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401 K +P P+ R ++ + EP P +A A +L Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377 Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461 ++ QA+ +G+ P P L P L L + K + + Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428 Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514 S A +P+P P N + S+ Q + +L+ GS + Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560 PG P ++ +GP P E + PPG VPE L + P+L Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546 Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620 + P Y + P + V + EL +SS + +AK S S P Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591 Query: 621 RP 622 +P Sbjct: 592 KP 593 Score = 33.9 bits (76), Expect = 0.60 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%) Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566 G PQ+ + G P P P PP PPP + P V + P+ + Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208 Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610 TP P + + P P P + G R G Q Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268 Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670 A+ + ASP PR PA KG GP P L P+ S P Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321 Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723 +P+ E+ +K S P RP Q + +P P ++ R +S++ Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 724 KQEKPASS 731 + ++ A + Sbjct: 382 QADERAGT 389 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 69.7 bits (169), Expect = 1e-11 Identities = 154/636 (24%), Positives = 213/636 (33%), Gaps = 141/636 (22%) Query: 74 PGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP-GSSLGSPPTIPGEAFPVSEHHQHSDLT 132 PG W L+ + SP S A P GS+LG P P FP S Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRS-------FK 303 Query: 133 APPNSP--TGHHP-QPASLIPSH--------PSSFGSPPHPHLLPTTPAAPFPAQASECP 181 PP +P T P Q A P PS PP H+ P + P A +CP Sbjct: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363 Query: 182 -VAAATAPHTP----GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 ATAP +P Q+ T P +PPP P LPPP Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-----------------APPLPPP 406 Query: 237 SSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRD 296 + PLP C K AH A P + L + + S ++ +S+ RD Sbjct: 407 AP-PLPPAAPPLPC-AQKAAHPP-AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463 Query: 297 GKFCDCCYCE-------------FFGHN-APPAAPTSRNYTEIREKLRSRLTRRKE--EL 340 + E F H P AP S+ K RL ++ L Sbjct: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE-----GKKGPRLPEKETLLSL 518 Query: 341 PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLA 400 P K T G+P E ++ + E + T P V + + + + E E A+L+ Sbjct: 519 PAKD-TPPGVP-EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELE-ARLS 575 Query: 401 AEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVC 460 + A K+A GS P+P E +C Sbjct: 576 SAAEKEAKPSIGSLPPKPRLE----------------------------------GGRIC 601 Query: 461 ELSMDSNGFSKEGAAEPEPQS---LPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAP 517 E D + SK A PQS LP ++L + P I +P P +A Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPP-----KAT 656 Query: 518 GEPAPPWAEMRGPHPPWTEVRGPPPGIVPENG--LVRRLNTVPNLSRVIWVKTPKPGYPS 575 PA P GP P GP + +G + T+P + + + Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716 Query: 576 SEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ-AKKSEASPAPRPPASLEVPS---- 630 E+P+S+EV + P G P + R +Q A+ S A P P EVP Sbjct: 717 PEKPASQEVST-----PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771 Query: 631 ------------------AKGQVAGPKQPGRVLELP 648 A+G AGP +P V E P Sbjct: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807 Score = 41.6 bits (96), Expect = 0.003 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 26/253 (10%) Query: 470 SKEGAAEPEPQSL--PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEM 527 S A P P L PP S + P + P TL SP T PAPP A + Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224 Query: 528 RGPHPPWTEVRGPPPG--------IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP 579 P PP P P + P G+ + + V R P +E Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284 Query: 580 SSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPK 639 S P+ + L P S P R S EA APR K + A K Sbjct: 285 GSALGPNPEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPR----------KEEGATKK 333 Query: 640 QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699 P R L LP A + P P G K G+++++ E+ Sbjct: 334 APSR-LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL----GQSQSQADERAG 388 Query: 700 VQPPGPARPQSLP 712 PP P P P Sbjct: 389 TPPPAPPLPPPAP 401 Score = 37.4 bits (85), Expect = 0.055 Identities = 117/542 (21%), Positives = 173/542 (31%), Gaps = 107/542 (19%) Query: 106 GSSLGSPPTIPGEA----FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH 161 G L PP PG A +SE S L +PP+ T P P L P P S PP Sbjct: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS--TAPPPPPLLLEPPPPPSMAPPPP 191 Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCS 221 P L +P PHT S P + PP F + P + Sbjct: 192 PVLEALSP------------------PHT-----------LSSPSIPTPPDFIPPAPPLA 222 Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSS 281 + P PPP P P P G + G + + E +S Sbjct: 223 -----FLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 282 SERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELP 341 RS + + F PP P + ++E ++ RKEE Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSF--KVPPPTPVRTSSIPVQE---AQEAPRKEEGA 330 Query: 342 MKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAA 401 K +P P+ R ++ + EP P +A A +L Sbjct: 331 TKKAP-SRLPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRL-----------G 377 Query: 402 EALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCE 461 ++ QA+ +G+ P P L P L L + K + + Sbjct: 378 QSQSQADERAGTPPPAPP----LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA----- 428 Query: 462 LSMDSNGFSKEGAAEPEPQSLPPSNLSGSS-------EQQPDINLDLSPLTLGSPQNHTL 514 S A +P+P P N + S+ Q + +L+ GS + Sbjct: 429 -GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 515 --QAPGEPAPPWAE--MRGPHPPWTE------VRGPPPGIVPENGL----VRRLNTVPNL 560 PG P ++ +GP P E + PPG VPE L + P+L Sbjct: 488 LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSL 546 Query: 561 SRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620 + P Y + P + V + EL +SS + +AK S S P Sbjct: 547 T------LPSVDYIPQDSP-TPSVRQIRNELEARLSSAAE--------KEAKPSIGSLPP 591 Query: 621 RP 622 +P Sbjct: 592 KP 593 Score = 33.9 bits (76), Expect = 0.60 Identities = 55/248 (22%), Positives = 82/248 (33%), Gaps = 30/248 (12%) Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWV 566 G PQ+ + G P P P PP PPP + P V + P+ + Sbjct: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208 Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKR----------------QGSQ 610 TP P + + P P P + G R G Q Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268 Query: 611 AKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWA 670 A+ + ASP PR PA KG GP P L P+ S P Sbjct: 269 AEATRASP-PRSPA-----EPKGSALGP-NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321 Query: 671 GSPKTEK---EKGSSWRNWPGEAKARPQEQ----ESVQPPGPARPQSLPQGKGRSRRSRN 723 +P+ E+ +K S P RP Q + +P P ++ R +S++ Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381 Query: 724 KQEKPASS 731 + ++ A + Sbjct: 382 QADERAGT 389 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 65.9 bits (159), Expect = 1e-10 Identities = 166/728 (22%), Positives = 231/728 (31%), Gaps = 92/728 (12%) Query: 82 PSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGH 141 P L+ G +P ++ P L +PP P + A P SP G Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-SPKGA 1194 Query: 142 HPQPASLIPSH------PSSFGSPPHPHLLPTTP----AAPFPAQASECPVAAATAPH-- 189 PA+ PS PS G+P P P +P A P P A P A +P Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254 Query: 190 --TPGPCQSSHLPSTSMPLLK---MPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPST 244 TP P + P+ + P LK PP G +P GP PP P P Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314 Query: 245 HRDPGCKGH------KFAHSGLACQLPQ-------PCEADEGLGEEEDSSSERSSCTSSS 291 P KG K A + A P P G SS+ ++ Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374 Query: 292 THQRDGKFCDCCYCEFFGH--NAPPAAPTSRNYTEIREKL--RSRLTRRKEELPMKGG-- 345 T G G +P PTS + K + +TR P KG Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434 Query: 346 -------TLGGIP------GEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKK 392 +L P G PA D L + PK P + + + KK Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP-KKA 1493 Query: 393 EKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDS 452 A + A L S P R R+ + L S+ K++ Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSR------RDPIAPTATLLSKKTPATLAPKEA 1547 Query: 453 IRASFSVCELSMDSNGFSKEGAAEPEPQS----LPPSNLSGSSEQQPDINLDLSPLTLGS 508 + + A P S PP+ + + P L P + S Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607 Query: 509 PQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT 568 P P PP E +GP P + P + P + L P + K Sbjct: 1608 PSPKEAPTPPAVTPPSPE-KGPATPAPKGTPTSPPVTPSS-----LKDSPTSPASVTCKM 1661 Query: 569 PKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKP--QKGKRQGSQAKKSEASPAPRPPASL 626 +S+ +K+ P+ +E+ + P R+G Q KKS A+ P P Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD-- 1719 Query: 627 EVPSAKGQVAGPKQ---PGRVLELPKVGSCAEAGEGSRGSRPGP-----GWAGSPKT--- 675 PSAK GP P +L + K S G+ + S GP A +P T Sbjct: 1720 --PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777 Query: 676 -----EKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730 K + +S P + P V P P + Q LP G S +K PA Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPV-PTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836 Query: 731 SLDDVFLP 738 +D LP Sbjct: 1837 --EDELLP 1842 Score = 51.2 bits (121), Expect = 4e-06 Identities = 60/232 (25%), Positives = 77/232 (33%), Gaps = 43/232 (18%) Query: 61 SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAF 120 +++ S + P G P + GL PH P + +PP+ G Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA--PTTPAATPPSPKG--- 1138 Query: 121 PVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA--------- 171 L PP P G PA+ PS +PP P PTTPAA Sbjct: 1139 ---------GLATPP--PKGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGL 1186 Query: 172 --PFPAQASECPVAAATAPH----TPGPCQSSHLPSTSMPL----LKMPPPFSGCSHPCS 221 P P A P A +P TP P + P+ + P L P P + P + Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246 Query: 222 GHCGGHCSGPLLPPPSSQPLPSTHRDPGCKG------HKFAHSGLACQLPQP 267 GP PPP P P P KG HK A + P P Sbjct: 1247 TPPSPK-GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297 Score = 42.7 bits (99), Expect = 0.001 Identities = 49/180 (27%), Positives = 59/180 (32%), Gaps = 27/180 (15%) Query: 97 SPHSSGAMPGSSLGSPPTIPGEAFP----VSEHHQHSDLTAPPNSPTGHHPQPASLIPSH 152 +P A P S G P T + P V+ A P P G PA+ PS Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP-FPKGASTPPAATPPSP 1043 Query: 153 PSSFGSPPHPHLLPTTPAAPFPA--------QASECPVAAATAPHTP--GPCQSSHLPST 202 S + P P PTTPAA P+ P A P +P GP S + Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103 Query: 203 SMPLLKMPPPFSGCSHPCSGHCGGHCS----------GPLLPPPSSQPLPSTHRDPGCKG 252 P P P G + P H G + G PPP P P KG Sbjct: 1104 MPPAATPPSPKGGLATP--PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161 Score = 42.4 bits (98), Expect = 0.002 Identities = 59/234 (25%), Positives = 79/234 (33%), Gaps = 34/234 (14%) Query: 41 LSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHS 100 +SHTS + + S +S+++SS D PS L P Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD-SPSP-LGVSVSPQTKRPPTK 811 Query: 101 SG-AMPGSSLG--SPPTIPGEAFPVSEH----HQHSDLTAPPNSPTGHHPQ----PASLI 149 G A P + +G S P P EA + E+ D A +SPT P+ P+++ Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871 Query: 150 PSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLK- 208 P P PP P+ PFP + P TP P Q+ L TS K Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKE----------GPATPAPKQAPALSMTSSSPKKA 921 Query: 209 ----------MPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKG 252 P G P + GP P P P P P KG Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975 Score = 41.6 bits (96), Expect = 0.003 Identities = 70/267 (26%), Positives = 93/267 (34%), Gaps = 43/267 (16%) Query: 472 EGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPL-TLGSPQNH--TLQAPGEPAPPWAE-- 526 +GA+ P P + PPS + +P TL SP+ T G P PP A Sbjct: 1030 KGASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088 Query: 527 --MRGPHPPWTEVRGPPPGIVP---ENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSS 581 GP P + PP P + GL + + +PK G + P Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT---PPP 1145 Query: 582 KEVPSCKQELPEPVSSGG---KPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGP 638 K P+ P P GG P KG A + A+ P P L PS KG P Sbjct: 1146 KGAPTTPAATP-PSPKGGLATPPPKG------APTTPAATPPSPKGGLATPSPKG---AP 1195 Query: 639 KQPGRVLELPKVGSCAEAGEGS-----------RGSRPGPGWAGSPKTEKEKGSSWRNWP 687 P PK G + +G+ +G P G+P T S + P Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255 Query: 688 GEAKARPQEQESVQPPGPARPQSLPQG 714 A P + + PP A P SL G Sbjct: 1256 ----ATPPPKGAPTPPA-ATPPSLKGG 1277 Score = 36.6 bits (83), Expect = 0.093 Identities = 49/176 (27%), Positives = 65/176 (36%), Gaps = 21/176 (11%) Query: 106 GSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSH--PSSFGSP--PH 161 G + +P P + S + AP P P+ A P+ PS G P P Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958 Query: 162 PHLLPTTPAAPFPA----QASECPVAAATAP-HTP-----GPCQSSHLPSTSMPLLKMPP 211 P PT PAA P+ A+ P A T P TP GP S + + P + P Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018 Query: 212 PFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQP 267 P S + G + P PPS + P+ P K A + A LP P Sbjct: 1019 PKG--SPAATPFPKGASTPPAATPPSPKGSPAATPLP-----KGAPTTPAATLPSP 1067 Score = 35.0 bits (79), Expect = 0.27 Identities = 56/255 (21%), Positives = 86/255 (33%), Gaps = 37/255 (14%) Query: 464 MDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPP 523 + N S +G+ + + P+ S P S +T SP+ TL P P Sbjct: 836 LPENSLSFQGSKDSPATTHSPTPPSPKGAPTP------SAVTPLSPKGVTLPPKETPTPS 889 Query: 524 WAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKP-GYPSSEEPSSK 582 + P GP + + ++ P +R TP P G P+S P Sbjct: 890 VVNLPFPK------EGPATPAPKQAPALSMTSSSPKKARA----TPAPKGIPASPSPKGA 939 Query: 583 EVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPG 642 P P ++ P+ G S K + PA PP+ P+ P P Sbjct: 940 PTP--------PAATPPSPKGGPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990 Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP 702 PK G + +G+ P P P + ++ +P A P + P Sbjct: 991 ATPPSPKGGPATPSPKGA----PTPPAVTPPSPKGSPAAT--PFPKGASTPP----AATP 1040 Query: 703 PGP-ARPQSLPQGKG 716 P P P + P KG Sbjct: 1041 PSPKGSPAATPLPKG 1055 Score = 30.8 bits (68), Expect = 5.1 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 24/96 (25%) Query: 98 PHSSGAMPGSSLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSF 156 P SS ++LG P PT+P PP SP PQ L ++ +S Sbjct: 27 PMSSALSVTAALGQPGPTLP-----------------PPCSPA---PQQCPLSAANQAS- 65 Query: 157 GSPPHPHLLPTTPA-APFPAQASECPVAAATAPHTP 191 P P + +TP PFP +S + TAP P Sbjct: 66 -PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP 100 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 63.5 bits (153), Expect = 7e-10 Identities = 80/300 (26%), Positives = 106/300 (35%), Gaps = 58/300 (19%) Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPP 523 G +G P +PQ PP S + P G PQ Q P P PP Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----------GKPQGPPPQGGNQPQGPPPP 135 Query: 524 WAEMRGPHPPW-TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSK 582 + +GP P + +GPPP P+ G + + SR K P +P Sbjct: 136 PGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194 Query: 583 EVPSCKQELPEPVSSG--------GKPQKGKRQGSQAKKSEASPA--------------- 619 P K + P P GKPQ QG +S SP Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254 Query: 620 --PRPPASLEVPSAKG--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKT 675 P PP + P +G + GP PG+ P G G SR SR PG P+ Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-----GSKSRSSRSPPG---KPQG 306 Query: 676 EKEKGSSWRNWPGEAKARPQE------QESVQPPGPARPQS-LPQGKGRSRRSRNKQEKP 728 +G + P +PQ + PP P +PQ PQG +SR +R+ KP Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366 Score = 63.2 bits (152), Expect = 9e-10 Identities = 72/254 (28%), Positives = 87/254 (34%), Gaps = 42/254 (16%) Query: 479 PQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPPWAEMRGPHPPW- 534 PQ PP G+ Q P P G PQ Q P P PP + +GP P Sbjct: 36 PQGAPPQG--GNKPQGP-------PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86 Query: 535 TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQ 589 + +GPPP G P+ R + P K P +P P K Sbjct: 87 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPG-------KPQGPPPQGGNQPQGPPPPPGKP 139 Query: 590 ELPEPVSSG--------GKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641 + P P GKPQ QG +S SP +P P Q GP P Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP--PPQGGNQPQGPPPP 197 Query: 642 -GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV 700 G+ P G G G GP P K S R+ PG+ + P Q Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGP-----PPQGDNKSQSARSPPGKPQG-PPPQGGN 251 Query: 701 QPPGPARPQSLPQG 714 QP GP P PQG Sbjct: 252 QPQGPPPPPGKPQG 265 Score = 58.5 bits (140), Expect = 2e-08 Identities = 71/273 (26%), Positives = 97/273 (35%), Gaps = 39/273 (14%) Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPPWAEMRGPHPPW 534 +PQ PP Q D S G PQ Q P P PP + +GP P Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208 Query: 535 -TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPE 593 + +GPPP P+ G + + +R K P +P P K + P Sbjct: 209 GNKPQGPPPPGKPQ-GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267 Query: 594 PVSSG--------GKPQKGKRQGSQAKKSEASPA-----------------PRPPASLEV 628 P GKPQ QG +S SP P PP + Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327 Query: 629 PSAKG--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNW 686 P +G + GP PG+ P G G SR +R PG P +++G++ + Sbjct: 328 PPPQGGNKPQGPPPPGKPQGPPPQG-----GSKSRSARSPPGKPQGPP--QQEGNNPQGP 380 Query: 687 PGEAKARPQEQESVQPPGPARPQSLPQGKGRSR 719 P A PQ+ ++ P P PQG SR Sbjct: 381 PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413 Score = 50.1 bits (118), Expect = 8e-06 Identities = 49/170 (28%), Positives = 65/170 (38%), Gaps = 26/170 (15%) Query: 576 SEEPSSKEVPSCKQELPE--PVSSGGKPQ-----KGKRQGSQAKKSEASPAPRPPASLEV 628 +E+ S +E PS P+ P G KPQ GK QG + P PP Sbjct: 20 NEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 79 Query: 629 ---PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRN 685 P + GP PG+ P G+ SR R PG P+ +G + Sbjct: 80 GPPPQGGNKPQGPPPPGKPQGPPP------QGDKSRSPRSPPG---KPQGPPPQGGNQPQ 130 Query: 686 WPGEAKARPQE------QESVQPPGPARPQSLP-QGKGRSRRSRNKQEKP 728 P +PQ + PP P +PQ P QG +SR SR+ KP Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP 180 Score = 35.4 bits (80), Expect = 0.21 Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 34/163 (20%) Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAE 526 G +G P +PQ PP S S + P G Q P P PP + Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ------PQGPPPPPGK 324 Query: 527 MRGPHPPW-TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPS 580 +GP P + +GPPP G P+ G R P KP P +E + Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP---------PGKPQGPPQQEGN 375 Query: 581 SKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPP 623 + + P P +GG PQ Q + PRPP Sbjct: 376 NPQGP--------PPPAGGNPQ----QPQAPPAGQPQGPPRPP 406 Score = 33.5 bits (75), Expect = 0.79 Identities = 46/178 (25%), Positives = 55/178 (30%), Gaps = 26/178 (14%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPG--EAFPVSEHHQHSDLTAPPNSPTGHHP- 143 N P PG G PP PG + P ++ +PP P G P Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186 Query: 144 ---QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GP 193 QP P G PP P P P P Q +A + P P P Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246 Query: 194 CQSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249 Q + P P P PP G + P G GP PP S+ PG Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSSRSPPG 302 Score = 33.1 bits (74), Expect = 1.0 Identities = 38/145 (26%), Positives = 45/145 (31%), Gaps = 21/145 (14%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFG 157 P G S SPP P + P +Q PP P G PQ + P P G Sbjct: 286 PPPQGGSKSRSSRSPPGKP-QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPG 343 Query: 158 SPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTSMPLLKMPPPFSG 215 P P P Q +A + P P P Q + P PPP G Sbjct: 344 KPQGP-----------PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP------PPPAGG 386 Query: 216 CSHPCSGHCGGHCSGPLLPPPSSQP 240 G GP PP +P Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQGGRP 411 Score = 32.3 bits (72), Expect = 1.8 Identities = 45/178 (25%), Positives = 54/178 (30%), Gaps = 26/178 (14%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPG--EAFPVSEHHQHSDLTAPPNSPTGHHP- 143 N P PG G PP PG + P ++ +PP P G P Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248 Query: 144 ---QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GP 193 QP P G PP P P P P Q ++ + P P P Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308 Query: 194 CQSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249 Q + P P P PP G + P G GP PP S PG Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSARSPPG 364 Score = 31.6 bits (70), Expect = 3.0 Identities = 45/177 (25%), Positives = 54/177 (30%), Gaps = 25/177 (14%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143 N P PG G PP PG+ P + + +PP P G P Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125 Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GPC 194 QP P G PP P P P P Q ++ + P P P Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185 Query: 195 QSSHLPSTSMPLLKMP--PPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPG 249 Q + P P P PP G + P G GP PP S PG Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDNKSQSARSPPG 240 Score = 31.2 bits (69), Expect = 3.9 Identities = 41/166 (24%), Positives = 53/166 (31%), Gaps = 18/166 (10%) Query: 87 SAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHP--- 143 SA L+ + S + G+ G+PP ++ +PP P G P Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPP---------QGGNKPQGPPSPPGKPQGPPPQGG 65 Query: 144 -QPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLPS 201 QP P G PP P P P Q + +P + PG Q Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125 Query: 202 TSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRD 247 + P PPP P G G GP PPP P D Sbjct: 126 GNQPQGPPPPPGKPQGPPPQG--GNKPQGP--PPPGKPQGPPPQGD 167 Score = 30.4 bits (67), Expect = 6.7 Identities = 37/145 (25%), Positives = 46/145 (31%), Gaps = 42/145 (28%) Query: 586 SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGR 643 S Q L E VS P G QG+ + P PS G+ GP G Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGP--------PSPPGKPQGPPPQG- 64 Query: 644 VLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPP 703 G +G P PG P P + +PQ PP Sbjct: 65 -------------GNQPQGPPPPPGKPQGP-------------PPQGGNKPQG-----PP 93 Query: 704 GPARPQSLPQGKGRSRRSRNKQEKP 728 P +PQ P +SR R+ KP Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPPGKP 118 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 60.8 bits (146), Expect = 5e-09 Identities = 72/281 (25%), Positives = 102/281 (36%), Gaps = 57/281 (20%) Query: 468 GFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---------PG 518 G S +G +P+ PP G Q N P G PQ Q PG Sbjct: 38 GPSPQGGNKPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95 Query: 519 EPAPP----WAEMRGPHPPWTEVRGPPP--GIVPENGLVRRLNTVPNLSRVIWVKTPKPG 572 +P P + +GP PP + +GPPP G P+ P PG Sbjct: 96 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG-------------------PPPPG 136 Query: 573 YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAK 632 P P + S P S GKPQ QG ++ P PP + P + Sbjct: 137 KPQGPPPQGDKSRS-------PRSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQ 185 Query: 633 G--QVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690 G + GP PG+ P G + + + G GP G + + PG+ Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP-----PGKP 240 Query: 691 KARPQE--QESVQPPGPARPQSLP-QGKGRSRRSRNKQEKP 728 + P + + PP P +PQ P QG +S+ +R+ KP Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281 Score = 60.5 bits (145), Expect = 6e-09 Identities = 70/264 (26%), Positives = 98/264 (37%), Gaps = 53/264 (20%) Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPA--PPWAEMRGPHPPWT 535 +PQ PP G+ Q P P G PQ Q P PP + +GP P Sbjct: 96 KPQGPPPQG--GNQPQGP-------PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146 Query: 536 EVRGP--PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPE 593 + R P PPG + P P PG P P + P Q P Sbjct: 147 KSRSPRSPPG--------KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP---QGPPP 195 Query: 594 PVSSGGKPQKGKRQGSQAKKSEASPA----------------PRPPASLEVPSAKG--QV 635 P GKPQ QG +++ S++ P P PP + P +G + Sbjct: 196 P----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251 Query: 636 AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695 GP PG+ G A+ G S+ +R PG P +++G++ + P A PQ Sbjct: 252 QGPPPPGK-----PQGPPAQGGSKSQSARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQ 304 Query: 696 EQESVQPPGPARPQSLPQGKGRSR 719 + ++ P P PQG SR Sbjct: 305 QPQAPPAGQPQGPPRPPQGGRPSR 328 Score = 60.1 bits (144), Expect = 8e-09 Identities = 72/259 (27%), Positives = 94/259 (36%), Gaps = 43/259 (16%) Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQA---PGEPAPP 523 G +G P +PQ PP S + P G PQ Q P P PP Sbjct: 65 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPP----------GKPQGPPPQGGNQPQGPPPP 114 Query: 524 WAEMRGPHPPW-TEVRGPPP-----GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSE 577 + +GP P +GPPP G P+ R + P K P Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPG-------KPQGPPPQGGN 167 Query: 578 EPSSKEVPSCKQELPEPVSSGGK-----PQKGKRQGSQAKKSEASPAPRPPASLEVPSAK 632 +P P K + P P GGK P GK QG + ++ + PP + P + Sbjct: 168 QPQGPPPPPGKPQGPPP--QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225 Query: 633 G--QVAGPKQP-GRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGE 689 G Q GP P G+ P G G G GP G K++ S R+ PG+ Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ-----SARSPPGK 280 Query: 690 AKARPQEQESVQPPGPARP 708 + PQ QE P GP P Sbjct: 281 PQGPPQ-QEGNNPQGPPPP 298 Score = 36.2 bits (82), Expect = 0.12 Identities = 43/166 (25%), Positives = 51/166 (30%), Gaps = 27/166 (16%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143 N P PG G PP PG+ P + + +PP P G P Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226 Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPF-----PAQASECPVAAATAPHTP--GPC 194 QP P G PP P P P PAQ +A + P P P Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286 Query: 195 QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 Q + P PPP G G GP PP +P Sbjct: 287 QEGNNPQGP------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326 Score = 32.7 bits (73), Expect = 1.3 Identities = 43/167 (25%), Positives = 51/167 (30%), Gaps = 19/167 (11%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHP-- 143 N P PG G PP PG+ P + + +PP P G P Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104 Query: 144 --QPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLP 200 QP P G PP P P P Q + +P + PG Q Sbjct: 105 GNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 164 Query: 201 STSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRD 247 + P PPP P G G GP PPP P D Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQG--GKKPQGP--PPPGKPQGPPPQGD 207 >gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 preproprotein [Homo sapiens] Length = 198 Score = 59.3 bits (142), Expect = 1e-08 Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 62/239 (25%) Query: 487 LSGSSEQQPDINLDLSP-LTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPP--G 543 LS + D++ + SP L G+PQ + Q +P +GP PP + +GPPP G Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKP-------QGPPPPPGKPQGPPPQGG 65 Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQK 603 P+ P PG P P + S + +P G PQ Sbjct: 66 NKPQG-------------------PPPPGKPQGPPPQGDKSRSPRSPPGKP--QGPPPQG 104 Query: 604 GKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGS 663 GK QG PP P + GP PG+ G A+ G S+ + Sbjct: 105 GKPQG-------------PP-----PQGGNKPQGPPPPGK-----PQGPPAQGGSKSQSA 141 Query: 664 RPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV---QPPGPARPQSLPQGKGRSR 719 R PG P +++G++ + P A PQ+ ++ QP GP RP PQG SR Sbjct: 142 RSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP---PQGGRPSR 195 Score = 36.2 bits (82), Expect = 0.12 Identities = 41/157 (26%), Positives = 50/157 (31%), Gaps = 20/157 (12%) Query: 96 NSPHSSGAMPGSSLGSPPT---------IPGEAF-PVSEHHQHSDLTAPPNSPTGHHPQP 145 N P PG G PP PG+ P + + +PP P G PQ Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104 Query: 146 ASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTS 203 P G+ P P P P PAQ +A + P P P Q + P Sbjct: 105 GKP-QGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 162 Query: 204 MPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 PPP G G GP PP +P Sbjct: 163 ------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 193 Score = 30.8 bits (68), Expect = 5.1 Identities = 39/157 (24%), Positives = 52/157 (33%), Gaps = 34/157 (21%) Query: 468 GFSKEGAAEP-EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAE 526 G +G P +PQ PP S + P P G PQ Q +P Sbjct: 65 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKP------ 118 Query: 527 MRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPS 586 +GP PP G P G + G + P KP P +E ++ + P Sbjct: 119 -QGPPPP-----GKPQGPPAQGGSKSQSARSP---------PGKPQGPPQQEGNNPQGP- 162 Query: 587 CKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPP 623 P +GG PQ Q + PRPP Sbjct: 163 -------PPPAGGNPQ----QPQAPPAGQPQGPPRPP 188 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 57.8 bits (138), Expect = 4e-08 Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 27/233 (11%) Query: 484 PSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPG 543 P + GS QQ + + P+ H G P PP A RGP P E R PPG Sbjct: 642 PPGVPGSVVQQEGLKGEQGA---PGPRGHQ----GAPGPPGA--RGPIGP--EGRDGPPG 690 Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQK 603 + G + P + ++ ++ P PG P P P LP + GKP Sbjct: 691 LQGLRGKKGDMGP-PGIPGLLGLQGP-PGPPGVPGPPG---PGGSPGLPGEIGFPGKPGP 745 Query: 604 GKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGS 663 G K P P PP + P +G+ P +PG E+ + G GE Sbjct: 746 PGPTGPPGKDGPNGP-PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804 Query: 664 RPG----PGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLP 712 PG PG G + EKG PG R ++ E+ GPA P LP Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGE--LGLPGLKGDRGEKGEA----GPAGPPGLP 851 Score = 43.1 bits (100), Expect = 0.001 Identities = 74/258 (28%), Positives = 90/258 (34%), Gaps = 32/258 (12%) Query: 471 KEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGP 530 KEG P PQ PS L G ++ D P G P PG P P A RGP Sbjct: 1223 KEGP--PGPQG--PSGLPGIPGEEGKEGRDGKPGPPGEPGK--AGEPGLPGPEGA--RGP 1274 Query: 531 HPPWTEVRGPP--PGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCK 588 P + G PG E+G + +P + K G + P P K Sbjct: 1275 -PGFKGHTGDSGAPGPRGESGAMG----LPGQEGLPG-KDGDTGPTGPQGPQGPRGPPGK 1328 Query: 589 QELP----EPVSSGGKPQKGKR--QGSQAKKSEASPA--PRPPASLEVPSAKGQVAGPKQ 640 P EP SG QKG + GS P P P VP +G P + Sbjct: 1329 NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388 Query: 641 PGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESV 700 PG E G +G +G G G G P KG + P + P E V Sbjct: 1389 PGFKGERGDPGI-----KGDKGPPGGKGQPGDPGIPGHKGHTGLMGP---QGLPGENGPV 1440 Query: 701 QPPGPARPQSLPQGKGRS 718 PPGP P +G S Sbjct: 1441 GPPGPPGQPGFPGLRGES 1458 Score = 40.4 bits (93), Expect = 0.006 Identities = 60/255 (23%), Positives = 86/255 (33%), Gaps = 42/255 (16%) Query: 517 PGEPAPPWAEMRGPHPPWTEVRGP--PPGIVPENGLVRRLNTVPNLSRVIWVKTPKP--- 571 PG P P + R P +GP PPG + G N V P P Sbjct: 876 PGLPGEPGLQGR---PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 932 Query: 572 ----------GYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASP--- 618 G P + ++ + ++ P PV G P G K + P Sbjct: 933 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 992 Query: 619 -APRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEK 677 +P P L +A G+V G + +CA G+ +G R PG GSP + Sbjct: 993 GSPGLPGPLGTKAACGKVRGSE------------NCALGGQCVKGDRGAPGIPGSPGSRG 1040 Query: 678 EKGSSWRNWPGEA-----KARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSL 732 + G PG + K P + PGP P G + R KP L Sbjct: 1041 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG-NPGERGPPGKP--GL 1097 Query: 733 DDVFLPKDMDGVEMD 747 + P D++ + D Sbjct: 1098 SSLLSPGDINLLAKD 1112 Score = 40.4 bits (93), Expect = 0.006 Identities = 58/213 (27%), Positives = 77/213 (36%), Gaps = 43/213 (20%) Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPP--PGIVPENGLVRRLNTVPNLSRVI 564 GSP + L PG P P R P RGPP PG+ + + L++ + Sbjct: 1060 GSPGSRGL--PGFPGPQGPAGRDGAPGNPGERGPPGKPGL----SSLLSPGDINLLAKDV 1113 Query: 565 WVKTPK--PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASP--AP 620 P PG P LP G P K R+G++ KK EA P P Sbjct: 1114 CNDCPPGPPGLPG---------------LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 1158 Query: 621 RPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG-PGWAGSPKTEKEK 679 PP +AGP+ G E G + G+ PG G G+P Sbjct: 1159 GPPG----------IAGPQ--GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 1206 Query: 680 GSSWRNWPGEAKARPQEQESVQPPGPARPQSLP 712 G + P + P ++ PPGP P LP Sbjct: 1207 GIAGAAGPPGIQGSPGKE---GPPGPQGPSGLP 1236 Score = 38.1 bits (87), Expect = 0.032 Identities = 35/145 (24%), Positives = 45/145 (31%), Gaps = 15/145 (10%) Query: 572 GYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631 G P E P + PS +P G+ K G K E P P + P Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG-LPGPEGARGPPGF 1277 Query: 632 KGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAK 691 KG PG G G+ PG G P + + G + P + Sbjct: 1278 KGHTGDSGAPGP--------------RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323 Query: 692 ARPQEQESVQPPGPARPQSLPQGKG 716 P + S PG P P KG Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKG 1348 Score = 32.7 bits (73), Expect = 1.3 Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 16/150 (10%) Query: 571 PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPS 630 PG P + SK + EL EP G P + +G Q P PP + P Sbjct: 538 PGPPGRD--GSKGMRGEPGELGEP----GLPGEVGMRGPQGPPG----LPGPPGRVGAPG 587 Query: 631 AKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690 +G+ G E G + G+ + RPGP P + EKG P Sbjct: 588 LQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP--QGEKGDVGPAGPPGV 645 Query: 691 KARPQEQESVQ----PPGPARPQSLPQGKG 716 +QE ++ PGP Q P G Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675 Score = 32.0 bits (71), Expect = 2.3 Identities = 51/172 (29%), Positives = 65/172 (37%), Gaps = 46/172 (26%) Query: 571 PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGS-------QAKKSEASPAPRPP 623 PG EP + P LP P+ G K GK +GS Q K + AP P Sbjct: 981 PGKGKDGEPGLRGSPG----LPGPL--GTKAACGKVRGSENCALGGQCVKGDRG-APGIP 1033 Query: 624 ASLEVPSAKGQ----VAGPKQPGRVLELPKVGSCAEAGEGSRGSR-----PGP----GWA 670 S P ++G VAGP P S +GS GSR PGP G Sbjct: 1034 GS---PGSRGDPGIGVAGPPGP----------SGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080 Query: 671 GSPKTEKEKGSSWRNW------PGEAKARPQEQESVQPPGPARPQSLPQGKG 716 G+P E+G + PG+ ++ + PPGP LP KG Sbjct: 1081 GAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG 1132 Score = 31.6 bits (70), Expect = 3.0 Identities = 31/93 (33%), Positives = 37/93 (39%), Gaps = 7/93 (7%) Query: 628 VPSAKGQVA--GPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR 684 +P KG + GP PG E VG G+G +G + G G P + KG R Sbjct: 494 LPGPKGDIGAIGPVGAPGPKGEKGDVG-IGPFGQGEKGEKGSLGLPGPPGRDGSKG--MR 550 Query: 685 NWPGEAKARPQEQESVQPPGPARPQSLPQGKGR 717 PGE P V GP P LP GR Sbjct: 551 GEPGEL-GEPGLPGEVGMRGPQGPPGLPGPPGR 582 Score = 30.8 bits (68), Expect = 5.1 Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 18/148 (12%) Query: 571 PGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPR--PPASLEV 628 PG P S +E +Q P P G P G + P R PP + Sbjct: 643 PGVPGSVV--QQEGLKGEQGAPGPRGHQGAP------GPPGARGPIGPEGRDGPPGLQGL 694 Query: 629 PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPG 688 KG + P PG + G G PGPG GSP E G + P Sbjct: 695 RGKKGDMGPPGIPGLL------GLQGPPGPPGVPGPPGPG--GSPGLPGEIGFPGKPGPP 746 Query: 689 EAKARPQEQESVQPPGPARPQSLPQGKG 716 P + PPGP + P +G Sbjct: 747 GPTGPPGKDGPNGPPGPPGTKGEPGERG 774 Score = 30.4 bits (67), Expect = 6.7 Identities = 53/209 (25%), Positives = 71/209 (33%), Gaps = 47/209 (22%) Query: 517 PGEPAPPWAE----MRGPHPPWTEVRGPP-----PGIVPENGLVRRLNTVPNLSRVIWVK 567 PG+P PP GP+ P GPP PG E+GL + P L I + Sbjct: 740 PGKPGPPGPTGPPGKDGPNGP----PGPPGTKGEPGERGEDGLPGK----PGLRGEIGEQ 791 Query: 568 --TPKPGYPSSEE-PSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP-- 622 +PG P + P + E + G G + G + +K EA PA P Sbjct: 792 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK-GDRGEKGEAGPAGPPGL 850 Query: 623 --PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKG 680 SL P P+ PG +G +G + PG G P + G Sbjct: 851 PGTTSLFTPH-------PRMPGE--------------QGPKGEKGDPGLPGEPGLQGRPG 889 Query: 681 SSWRNWP-GEAKARPQEQESVQPPGPARP 708 P G A+ QE P P Sbjct: 890 ELGPQGPTGPPGAKGQEGAHGAPGAAGNP 918 Score = 30.4 bits (67), Expect = 6.7 Identities = 52/221 (23%), Positives = 78/221 (35%), Gaps = 35/221 (15%) Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPL-TLGSPQNHTLQA----PGEPAPPWAEMRGP 530 EP P P S P + L P G P + PG+P P + Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396 Query: 531 HPPWTEVRGPP--------PGIVPENGLVRRLNT--VPNLSRVIWVKTP--KPGYPS--S 576 P +GPP PGI G + +P + + P +PG+P Sbjct: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456 Query: 577 EEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVA 636 E PS + + QE + GK+ ++ A PPA ++ S++G+ Sbjct: 1457 ESPSMETLRRLIQE-----------ELGKQLETRLAYLLAQ---MPPAYMK--SSQGRPG 1500 Query: 637 GPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEK 677 P PG+ + G E G +G GP PK E+ Sbjct: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 57.4 bits (137), Expect = 5e-08 Identities = 66/233 (28%), Positives = 88/233 (37%), Gaps = 45/233 (19%) Query: 487 LSGSSEQQPDINLDLSPLTL-GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIV 545 LS + D++ + S + G P+ Q +P P P PP G P G Sbjct: 13 LSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRP------PPPP-----GKPQGPP 61 Query: 546 PENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGK 605 P+ G N S+ P PG P P + P GKP++ Sbjct: 62 PQGG---------NQSQG---PPPPPGKPEGRPPQGGN------QSQGPPPHPGKPERPP 103 Query: 606 RQGSQAKKSEASPAPRPPASLEVPSAKGQVAG---PKQPGRVLELPKVGSCAEAGEGSRG 662 QG +++ P PP E P +G P PG+ P G G S+G Sbjct: 104 PQGG----NQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQG-----GNQSQG 154 Query: 663 SRPGPGWA-GSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQG 714 P PG G P E K S R+ PG+ + PQ QE +P GP P PQG Sbjct: 155 PPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQ-QEGNKPQGPP-PPGKPQG 205 Score = 46.6 bits (109), Expect = 9e-05 Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 29/174 (16%) Query: 575 SSEEPSSKE---VPSCKQELPEPVSSGGKPQK-----GKRQGSQAKKSEASPAPRPPASL 626 SSE+ S +E + S K E P G +PQ+ GK QG + S P PP Sbjct: 19 SSEDVSQEESLFLISGKPEGRRP-QGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGK 77 Query: 627 ---EVPSAKGQVAGPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682 P Q GP PG+ P G G S+G+ P PG P+ +G + Sbjct: 78 PEGRPPQGGNQSQGPPPHPGKPERPPPQG-----GNQSQGTPPPPG---KPERPPPQGGN 129 Query: 683 WRNWPGEAKARPQE-------QESVQPPGPARPQSLPQGKG-RSRRSRNKQEKP 728 + P +P+ Q PP P +P+ P +G +SR +R+ KP Sbjct: 130 QSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKP 183 Score = 38.9 bits (89), Expect = 0.019 Identities = 43/163 (26%), Positives = 51/163 (31%), Gaps = 24/163 (14%) Query: 98 PHSSGAMPGSSLGSPPTIPG--EAFPVSEHHQHSDLTAPPNSPT---------GHHPQPA 146 P G+ PP PG E P +Q PP P H P P Sbjct: 78 PEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP 137 Query: 147 SLIPSHP------SSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSS-HL 199 P P S G PPHP P P P + ++ A + GP Q + Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPG----KPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNK 193 Query: 200 PSTSMPLLKM--PPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 P P K PPP G G GP PP +P Sbjct: 194 PQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRP 236 Score = 37.0 bits (84), Expect = 0.071 Identities = 54/198 (27%), Positives = 62/198 (31%), Gaps = 39/198 (19%) Query: 61 SSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGL----WNSPHSSGAMPGSSLGSPPTIP 116 SS+ SSS S + S FL + K G N P PG G PP Sbjct: 14 SSAESSSEDVSQ--------EESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPP--- 62 Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFP-- 174 +Q PP P G PQ + S G PPH P P P P Sbjct: 63 ------QGGNQSQGPPPPPGKPEGRPPQGGN------QSQGPPPH----PGKPERPPPQG 106 Query: 175 ---AQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGP 231 +Q + P P G Q SH P + PPP G G GP Sbjct: 107 GNQSQGTPPPPGKPERPPPQGGNQ-SHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGP 165 Query: 232 LLPPPSSQPLPSTHRDPG 249 PP S PG Sbjct: 166 --PPQEGNKSRSARSPPG 181 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 56.2 bits (134), Expect = 1e-07 Identities = 59/178 (33%), Positives = 70/178 (39%), Gaps = 20/178 (11%) Query: 31 TGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHK 90 TG + A S S S S S SSSSSSSSSSSSSSSS +S SS S+ Sbjct: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656 Query: 91 LSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNS----PTGHHPQPA 146 S +S SS + + S + EA P TA P++ PT Q Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP--------TAGPSAQAALPTKATKQAG 2708 Query: 147 SLIPS--HPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPST 202 PS P P P P P P P A A A P + HLP+T Sbjct: 2709 KARPSAHSPGKKTPAPQPQAPPPQPTQPLQ------PKAQAGAKSRPKKREGVHLPTT 2760 Score = 44.7 bits (104), Expect = 3e-04 Identities = 41/128 (32%), Positives = 52/128 (40%), Gaps = 6/128 (4%) Query: 19 SCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSG 78 S S + + + S S +S S S S SSSSSSSSSSSSSSSS ++ Sbjct: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673 Query: 79 DWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAP-PNS 137 D D S P + A+P + G+A P S H AP P + Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ----AGKARP-SAHSPGKKTPAPQPQA 2728 Query: 138 PTGHHPQP 145 P QP Sbjct: 2729 PPPQPTQP 2736 Score = 40.4 bits (93), Expect = 0.006 Identities = 52/189 (27%), Positives = 73/189 (38%), Gaps = 33/189 (17%) Query: 49 QSCGDDSHSSSSSSSSSSSSSSSSCPGNS-------GDWD--------------PSSFLS 87 Q ++S SSSSSSS SSSSSSSS S GD + SS + Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610 Query: 88 AHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPAS 147 + S +S SS + SS S + + S S ++ +S + +S Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670 Query: 148 LIPSHPSSFGS----PPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTS 203 SS S P P P+ AA P +A++ A + H+PG T Sbjct: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAA-LPTKATKQAGKARPSAHSPG-------KKTP 2722 Query: 204 MPLLKMPPP 212 P + PPP Sbjct: 2723 APQPQAPPP 2731 Score = 35.8 bits (81), Expect = 0.16 Identities = 57/209 (27%), Positives = 79/209 (37%), Gaps = 28/209 (13%) Query: 105 PGSSLGSPPTIPGEA-FPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPH 163 PGS P + A P + APP + P+P + +P+ +S P Sbjct: 2370 PGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAP--- 2426 Query: 164 LLPTTPAA-PFPAQASECPVAAATAPHTPGP-----CQSSHLPSTSMP--------LLKM 209 L T PA P P +A + A P PG + H TS LL+ Sbjct: 2427 -LITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRE 2485 Query: 210 PPPFSGCSHPCSGHCGGH------CSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQ 263 P G P S G S P P P + ++PG G F SG + Sbjct: 2486 DPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATD-GDLAQEPG-PGLTFEDSGNP-K 2542 Query: 264 LPQPCEADEGLGEEEDSSSERSSCTSSST 292 P +A++ EE +SSS SS +SSS+ Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSS 2571 Score = 32.3 bits (72), Expect = 1.8 Identities = 72/308 (23%), Positives = 100/308 (32%), Gaps = 71/308 (23%) Query: 475 AEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPW 534 AEP P L PS S + D T GS + +A G P A+ +G Sbjct: 2289 AEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGA-KARGRGRKPSAKAKGDRAAT 2347 Query: 535 TEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEP 594 E P + P P + EPSS P K+ PEP Sbjct: 2348 LEEGNPTDEV--------------------------PSTPLALEPSS--TPGSKKSPPEP 2379 Query: 595 VSSGGKPQKGKRQGSQAKKSEASPA-----PRPPA--SLEVPSAKGQVAGPK---QPGRV 644 V +AK +A PA P PPA S P ++ P P + Sbjct: 2380 VDK------------RAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427 Query: 645 LEL------PKVGSCAEAGEGSRGSRPGP----------GWAGSPKTEKEKGS-SWRNWP 687 + + PK AE RPG SPK++K K + R P Sbjct: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487 Query: 688 GEAK-ARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSL--DDVFLPKDMDGV 744 G P+ S+ PA S P+ + ++P L +D PK D Sbjct: 2488 GAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKA 2547 Query: 745 EMDETDRE 752 + ++ E Sbjct: 2548 QAEQDGAE 2555 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 56.2 bits (134), Expect = 1e-07 Identities = 41/124 (33%), Positives = 50/124 (40%), Gaps = 15/124 (12%) Query: 133 APPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG 192 APP +P G PA+ + P +PP P P AA PA+A AAATAP +PG Sbjct: 110 APPRAPRG---APAAAAAAAPPPTPAPPPP---PAPVAAAAPARAPRAAAAAATAPPSPG 163 Query: 193 PCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGH--------CSGPLLPPPSSQPLPST 244 P Q + P L PPP + G P LPPP P P Sbjct: 164 PAQPGPRAQRAAP-LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222 Query: 245 HRDP 248 + P Sbjct: 223 QQQP 226 Score = 38.9 bits (89), Expect = 0.019 Identities = 63/261 (24%), Positives = 88/261 (33%), Gaps = 43/261 (16%) Query: 520 PAPPWAEMRGPH------PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGY 573 PAPP A P PP T PPP V R P + P PG Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR----APRAAAAAATAPPSPGP 164 Query: 574 ----PSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVP 629 P ++ + P P V+ P++ A++ P P+PPA Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA----- 219 Query: 630 SAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSR--------PGPGWAGSPKT------ 675 + Q P QP + P G AG +R G G AG T Sbjct: 220 PPQQQQPPPPQP----QPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275 Query: 676 --EKE---KGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730 E+E +G R G A A P+ + P A + +G R K+E+ Sbjct: 276 LLEEEAAARGRLERTRLG-ALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDD 334 Query: 731 SLDDVFLPKDMDGVEMDETDR 751 D+ +G E+ E+DR Sbjct: 335 DEDEDEEDDVSEGSEVPESDR 355 Score = 33.9 bits (76), Expect = 0.60 Identities = 74/333 (22%), Positives = 105/333 (31%), Gaps = 81/333 (24%) Query: 100 SSGAMPGSSLGSPPTIP-GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGS 158 ++ A P + PP P A P + P SP P P + + + Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRA---QRAAPLAA 179 Query: 159 PPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSH 218 PP P A P + + P AA P P P Q P P P P Sbjct: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP------ 233 Query: 219 PCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEE 278 P G G +G P S + + G G + + +GL EEE Sbjct: 234 PPEG--GAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRV-----------QGLLEEE 280 Query: 279 DSSSERSSCT-----SSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRL 333 ++ R T + R G+ APPAA S + + R+ Sbjct: 281 AAARGRLERTRLGALALPRGDRPGR-------------APPAA--SARPSRSKRGGEERV 325 Query: 334 TRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKE 393 ++EE + D DE E S +VP S R A H+L Sbjct: 326 LEKEEE-----------------EDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQL---- 364 Query: 394 KEKAQLAAEALKQANRVSGSREPRPARERLLEW 426 +G R P+ A+ER+ EW Sbjct: 365 -----------------NGERGPQSAKERVKEW 380 Score = 32.0 bits (71), Expect = 2.3 Identities = 33/128 (25%), Positives = 39/128 (30%), Gaps = 8/128 (6%) Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVG- 651 +P G P R A + A+ AP P + P A A P + R Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159 Query: 652 -SCAEAGEGSRGSR------PGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPG 704 S A G R R P P A P G P A P QPP Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219 Query: 705 PARPQSLP 712 P + Q P Sbjct: 220 PPQQQQPP 227 >gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] Length = 379 Score = 55.8 bits (133), Expect = 1e-07 Identities = 61/244 (25%), Positives = 82/244 (33%), Gaps = 39/244 (15%) Query: 483 PPSNLSGSSEQQPDINLDLSPLTLGSPQNHTL-QAPGEPAPPWAEMRGPHPPWTEVRGPP 541 P G+ E P L+ L P+ +L PGE A +RGP P P Sbjct: 25 PRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAP 84 Query: 542 PGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKP 601 G+ + +W T +PG P++ +V +C + E GG P Sbjct: 85 DGL-----------------KHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFP 127 Query: 602 QKGKRQGS------------QAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPK 649 G R + ++ S AS PRP LE P + P++P P Sbjct: 128 HFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLE-PQRGPAASPPQEPSSRPPSPP 186 Query: 650 VGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQ 709 G E GPG A P + N P A P S P PA P Sbjct: 187 AGLSTEPA--------GPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPG 238 Query: 710 SLPQ 713 L Q Sbjct: 239 DLRQ 242 Score = 39.3 bits (90), Expect = 0.014 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 10/80 (12%) Query: 127 QHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA----PFPAQASECPV 182 Q +PP P+ P P + + + P+ G+ P P LP PA P PA A E P Sbjct: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRP-FLPGQPAEVDGNPPPA-APEAPA 224 Query: 183 A----AATAPHTPGPCQSSH 198 A A+ AP PG + H Sbjct: 225 ASPSTASPAPAAPGDLRQEH 244 Score = 31.2 bits (69), Expect = 3.9 Identities = 35/137 (25%), Positives = 44/137 (32%), Gaps = 39/137 (28%) Query: 116 PGEAFPVSEHHQHSDLT---APPNSPTGHHPQ--PASLIPSHPSSFGSPPHPHLLPTTPA 170 PG P H + S + APP G PQ PA+ P PSS PP P Sbjct: 137 PGRC-PAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSS--RPPSP-------- 185 Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230 P +T P PG LP + PPP + Sbjct: 186 ----------PAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAP-------------EA 222 Query: 231 PLLPPPSSQPLPSTHRD 247 P P ++ P P+ D Sbjct: 223 PAASPSTASPAPAAPGD 239 >gi|28559039 mediator complex subunit 1 [Homo sapiens] Length = 1581 Score = 54.7 bits (130), Expect = 3e-07 Identities = 70/272 (25%), Positives = 112/272 (41%), Gaps = 42/272 (15%) Query: 50 SCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSL 109 S G SH S SSSSSSS+S+S + + SS LS S +++S SSG+ + Sbjct: 1091 SSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLS----SSMYSSQGSSGSSQSKNS 1146 Query: 110 GSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLI----------PSH------P 153 PG + P+++H S ++ P G +P+SL+ PSH Sbjct: 1147 SQSGGKPGSS-PITKHGLSSGSSSTKMKPQG---KPSSLMNPSLSKPNISPSHSRPPGGS 1202 Query: 154 SSFGSPPHPHLLPTTPAAPFPAQASECPVAAAT-APHTPGPCQSSHLPSTS------MPL 206 SP P +P TP P+ ++ P+++ + H G SS + S+S Sbjct: 1203 DKLASPMKP--VPGTP----PSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256 Query: 207 LKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQ 266 K PP + C+ S SG + +Q S + P + K + + + +L Sbjct: 1257 QKTPPSSNSCTASSSSFSS---SGSSMSSSQNQHGSSKGKSPS-RNKKPSLTAVIDKLKH 1312 Query: 267 PCEADEGLGEEEDSSSERSSCTSSSTHQRDGK 298 G G E+ + T+SS+H K Sbjct: 1313 GV-VTSGPGGEDPLDGQMGVSTNSSSHPMSSK 1343 Score = 37.0 bits (84), Expect = 0.071 Identities = 45/180 (25%), Positives = 63/180 (35%), Gaps = 17/180 (9%) Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASL 626 K PK +E S S + P P S+GG G SQ A+P P P ++ Sbjct: 1008 KPPKRKKADTEGKSPSHSSSNRPFTP-PTSTGGSKSPGSAGRSQTPPGVATP-PIPKITI 1065 Query: 627 EVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSR--GSRPGPGWAGSPKTEKEKGSSWR 684 ++P V P + V S S S +G K+ K +GSS Sbjct: 1066 QIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125 Query: 685 NWPGE------AKARPQEQESVQPPGPARPQSLPQGK-----GRSRRSRNKQEKPASSLD 733 + Q + S Q G +P S P K G S Q KP+S ++ Sbjct: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGG--KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMN 1183 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 54.7 bits (130), Expect = 3e-07 Identities = 72/275 (26%), Positives = 102/275 (37%), Gaps = 53/275 (19%) Query: 470 SKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPLTLGSPQNHTLQAPGEPAPPWAEMR 528 S+ G A+P Q PS L+ QQP + + P P L PA P A+ Sbjct: 324 SQPGPAKPPAQ---PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG----PAKPPAQQT 376 Query: 529 GPHPPWTEVRGP-----PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKE 583 G P +E GP PPG+ G P V TPKP +++P + Sbjct: 377 GSEKPSSEQPGPKALAQPPGV----GKTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQS 429 Query: 584 VPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP-RPPASLEVPSAKGQVAGPKQPG 642 PV G + +Q K S P +PP+ L P+ P+QPG Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP----PQQPG 485 Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR---NWPGEAKARPQEQES 699 ++P P GS K ++ S + PG AK PQ+ S Sbjct: 486 P-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 700 VQP----PGPARPQSLPQGKGRSRRSRNKQEKPAS 730 +P PG A+P + Q ++ S + KP S Sbjct: 527 TKPPSQQPGSAKPSA--QQPSPAKPSAQQSTKPVS 559 Score = 47.0 bits (110), Expect = 7e-05 Identities = 133/601 (22%), Positives = 196/601 (32%), Gaps = 111/601 (18%) Query: 112 PPTIPGE-AFPVSEHHQHSDLTAPPNS------PTGHHPQPASLIPSHPSSFGSPPH-PH 163 P IP + A P Q + T PP+ P P PA P P S P P Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 164 LLPTTPAAPFPAQASECPVAAATAPHTPGPCQS-SHLPSTSMPLLKMPPPFSGCSHPCSG 222 P P PA+ S P PG + S P ++ P + P P + + Sbjct: 506 STKPPPQQPGPAKPS---------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556 Query: 223 HCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSS 282 SG L PP+ P S + P GL + C E L + ++ Sbjct: 557 PVSQTGSGKPLQPPTVSP--SAKQPPS--------QGLPKTICPLCNTTELLLHVPEKAN 606 Query: 283 ERSSCTSSST------------HQRDGKFCDCCYCEFF----GHNAP-PAAP-------- 317 ++CT T H + K C C+ G AP P++P Sbjct: 607 F-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665 Query: 318 ----------------TSRNYTEIREKLRSRLTRRKEELPM-KGGTLGGIPGEPAVDHRD 360 TS ++ S+ K+ P+ K TL G P A + Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725 Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420 D L + EP VP+ E++KA +A + KQ V + + + Sbjct: 726 ADSLSKPAPPKEPSVPS---------------EQDKAPVADDKPKQPKMVKPTTDLVSSS 770 Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480 + PD +V S + T DS + S S + F + P Sbjct: 771 SATTK-PDIPSSKVQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827 Query: 481 SLPPSNLSGSSEQQPDINLD--------LSPLTLGSPQNHTLQAP-GEPAPPWAEMRGPH 531 S S+ SSE + +D T SP+ P G P PP GP Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPR 882 Query: 532 PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEV---PSCK 588 P + P RR + NL + +P P E + K S Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSL--NLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIF 939 Query: 589 QELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELP 648 + +S+ G+P + G A +A +PP S P + GQ P P + + + Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVK 997 Query: 649 K 649 K Sbjct: 998 K 998 Score = 46.2 bits (108), Expect = 1e-04 Identities = 89/426 (20%), Positives = 147/426 (34%), Gaps = 64/426 (15%) Query: 336 RKEEL----PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPN---SARAAKRARHK 388 RK+EL P K PG PA + S E K+P S + K ++ + Sbjct: 83 RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRS-EQKLPGRSPSTISLKESKSR 141 Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSF---LSSRLQEI 445 KE+ K+ + L + N +S +++ N F S + Sbjct: 142 TDLKEEHKSSMMPGFLSEVNALSAVSSV--------------VNKFNPFDLISDSEASQE 187 Query: 446 KNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPL 504 + T K + + EG +P Q PP + D + D +P Sbjct: 188 ETTKKQKV----------VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK 237 Query: 505 TLGSPQNHTL--QAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPEN---GLVRRLNTVPN 559 ++ S Q + Q PG P + P ++ P+ +VR + P+ Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297 Query: 560 LSRVIW--VKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEAS 617 L ++ P PG P +++P ++ P P +P G + + Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK------SQPGPAKPPAQPS-GLTKPLAQQPGTVK 350 Query: 618 PAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG--------PGW 669 P +PP + + P+ Q GP +P + S + G + PG PG Sbjct: 351 PPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407 Query: 670 AGSPKTEKEKGSSWRNWPG---EAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQE 726 A P + PG AKA + VQ PGP + + G G++ + Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467 Query: 727 KPASSL 732 KP S L Sbjct: 468 KPPSQL 473 Score = 43.5 bits (101), Expect = 8e-04 Identities = 142/687 (20%), Positives = 219/687 (31%), Gaps = 121/687 (17%) Query: 97 SPHSSGAMPG-SSLGSPPTI-------PGEAFPVSEH-------HQHSDLTAPPNSPTG- 140 S S PG +L PP + PG A P ++ Q L +P +P Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437 Query: 141 ----HHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS 196 P P IP+ + G PT P + P A P A P S Sbjct: 438 KTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496 Query: 197 SHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP---LPSTHRDPGCKGH 253 + PS K PP G + P S G P P S++P PS + + Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKP-SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555 Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ------RDGKF-----CDC 302 K + + QP + ++ C +T + F C Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615 Query: 303 CYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVD 362 C G N P + TE++E L ++ GG L +P P Sbjct: 616 TVCSLCGFNPNP------HLTEVKEWLCLNCQMKR----ALGGDLAPVPSSP-------- 657 Query: 363 ELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARER 422 +PK+ + A K + ++ + A KQ S+ P P + Sbjct: 658 ---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----DLSKAPEPKKPP 704 Query: 423 LLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSL 482 L VK + S A P+ S+ Sbjct: 705 PL------------------------VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740 Query: 483 PPSN----LSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVR 538 P ++ +QP + + L S P AE + P T+ Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 539 GPPPGIVPENGLVRRLNT--VP---NLSRVIWVKTPKPGYPSSEEPSSKEV-PSCKQELP 592 P P V ++ +P + S++I PG PSSE K+V P K+E P Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKII----SHPG-PSSESKGQKQVDPVQKKEEP 855 Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGS 652 + + P+ + K S P PRP A VP+ + Q P++ R L +GS Sbjct: 856 KKAQTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPTPQ-QSPKPQEQSRRFSL-NLGS 911 Query: 653 CAEAGEGSRGSRPGP-------GWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705 +A + S+ + P G+ S ++ S PG Q P P Sbjct: 912 ITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970 Query: 706 ARPQSLPQGKGRSRRSRNKQEKPASSL 732 ++P P +G + + PA S+ Sbjct: 971 SQP---PTSQGPPKSTGQAPPAPAKSI 994 Score = 32.0 bits (71), Expect = 2.3 Identities = 53/193 (27%), Positives = 67/193 (34%), Gaps = 30/193 (15%) Query: 79 DWDPSSFLSAHKLSGLWNSPHSSGAM-----PGSSL--GSPPTIPGEAFPVSEHHQHS-D 130 D PSS ++ L + +SG P S L GSP A P S D Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400 Query: 131 LTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA------- 183 ++A P P P P P PP P L P T P + VA Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453 Query: 184 ----AATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ 239 A T T +S+ LP T + PP S SG H P PP + + Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513 Query: 240 P----LPSTHRDP 248 P LP+T + P Sbjct: 2514 PVIPQLPTTTQKP 2526 Score = 30.4 bits (67), Expect = 6.7 Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 11/130 (8%) Query: 112 PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH-PHLLPTTPA 170 P IP + P + Q P S + P+ I S P G P P P T Sbjct: 216 PKPIPKQQGPGRDPLQQD---GTPKSISSQQPEK---IKSQPPGTGKPIQGPTQTPQTDH 269 Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230 A P Q A G LPS S P ++ P P P + G S Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP----GKPPAQQPGHEKSQ 325 Query: 231 PLLPPPSSQP 240 P P +QP Sbjct: 326 PGPAKPPAQP 335 Score = 30.0 bits (66), Expect = 8.7 Identities = 55/248 (22%), Positives = 75/248 (30%), Gaps = 34/248 (13%) Query: 9 LGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSS 68 L E+ W+C +C+ +R G + A S K+ S S SS +S Sbjct: 629 LTEVKEWLCLNCQM-----KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683 Query: 69 SSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH 128 D P LS +P P L PT+ G ++ Sbjct: 684 PKK-------DAAPKQDLS--------KAPEPKKPPP---LVKQPTLHGSPSAKAKQPPE 725 Query: 129 SDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAP 188 +D + P P PS PS P P P P +A T P Sbjct: 726 ADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 189 HTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDP 248 P S + P LK S P +G +P P+S +H P Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836 Query: 249 G--CKGHK 254 KG K Sbjct: 837 SSESKGQK 844 Score = 30.0 bits (66), Expect = 8.7 Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 25/167 (14%) Query: 577 EEPSSKEVPSCKQEL-PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQV 635 E K+ S QE P P P++ K + + K P P +P AK Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK--T 1254 Query: 636 AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695 + P++ L +V E EG +PKT +E G PQ Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLEGRV----------APKTVQEGKQPQTKMEGLPSGTPQ 1304 Query: 696 E------------QESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730 +E QPP A+P + GK ++ + +K + +S Sbjct: 1305 SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 54.7 bits (130), Expect = 3e-07 Identities = 72/275 (26%), Positives = 102/275 (37%), Gaps = 53/275 (19%) Query: 470 SKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPLTLGSPQNHTLQAPGEPAPPWAEMR 528 S+ G A+P Q PS L+ QQP + + P P L PA P A+ Sbjct: 324 SQPGPAKPPAQ---PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG----PAKPPAQQT 376 Query: 529 GPHPPWTEVRGP-----PPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKE 583 G P +E GP PPG+ G P V TPKP +++P + Sbjct: 377 GSEKPSSEQPGPKALAQPPGV----GKTPAQQPGPAKPPTQQVGTPKP---LAQQPGLQS 429 Query: 584 VPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP-RPPASLEVPSAKGQVAGPKQPG 642 PV G + +Q K S P +PP+ L P+ P+QPG Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP----PQQPG 485 Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWR---NWPGEAKARPQEQES 699 ++P P GS K ++ S + PG AK PQ+ S Sbjct: 486 P-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 700 VQP----PGPARPQSLPQGKGRSRRSRNKQEKPAS 730 +P PG A+P + Q ++ S + KP S Sbjct: 527 TKPPSQQPGSAKPSA--QQPSPAKPSAQQSTKPVS 559 Score = 47.0 bits (110), Expect = 7e-05 Identities = 133/601 (22%), Positives = 196/601 (32%), Gaps = 111/601 (18%) Query: 112 PPTIPGE-AFPVSEHHQHSDLTAPPNS------PTGHHPQPASLIPSHPSSFGSPPH-PH 163 P IP + A P Q + T PP+ P P PA P P S P P Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 164 LLPTTPAAPFPAQASECPVAAATAPHTPGPCQS-SHLPSTSMPLLKMPPPFSGCSHPCSG 222 P P PA+ S P PG + S P ++ P + P P + + Sbjct: 506 STKPPPQQPGPAKPS---------PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556 Query: 223 HCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSS 282 SG L PP+ P S + P GL + C E L + ++ Sbjct: 557 PVSQTGSGKPLQPPTVSP--SAKQPPS--------QGLPKTICPLCNTTELLLHVPEKAN 606 Query: 283 ERSSCTSSST------------HQRDGKFCDCCYCEFF----GHNAP-PAAP-------- 317 ++CT T H + K C C+ G AP P++P Sbjct: 607 F-NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665 Query: 318 ----------------TSRNYTEIREKLRSRLTRRKEELPM-KGGTLGGIPGEPAVDHRD 360 TS ++ S+ K+ P+ K TL G P A + Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725 Query: 361 VDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPAR 420 D L + EP VP+ E++KA +A + KQ V + + + Sbjct: 726 ADSLSKPAPPKEPSVPS---------------EQDKAPVADDKPKQPKMVKPTTDLVSSS 770 Query: 421 ERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480 + PD +V S + T DS + S S + F + P Sbjct: 771 SATTK-PDIPSSKVQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827 Query: 481 SLPPSNLSGSSEQQPDINLD--------LSPLTLGSPQNHTLQAP-GEPAPPWAEMRGPH 531 S S+ SSE + +D T SP+ P G P PP GP Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP-----GPR 882 Query: 532 PPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEV---PSCK 588 P + P RR + NL + +P P E + K S Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSL--NLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIF 939 Query: 589 QELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELP 648 + +S+ G+P + G A +A +PP S P + GQ P P + + + Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVK 997 Query: 649 K 649 K Sbjct: 998 K 998 Score = 46.2 bits (108), Expect = 1e-04 Identities = 89/426 (20%), Positives = 147/426 (34%), Gaps = 64/426 (15%) Query: 336 RKEEL----PMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPN---SARAAKRARHK 388 RK+EL P K PG PA + S E K+P S + K ++ + Sbjct: 83 RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRS-EQKLPGRSPSTISLKESKSR 141 Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSF---LSSRLQEI 445 KE+ K+ + L + N +S +++ N F S + Sbjct: 142 TDLKEEHKSSMMPGFLSEVNALSAVSSV--------------VNKFNPFDLISDSEASQE 187 Query: 446 KNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPD-INLDLSPL 504 + T K + + EG +P Q PP + D + D +P Sbjct: 188 ETTKKQKV----------VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK 237 Query: 505 TLGSPQNHTL--QAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPEN---GLVRRLNTVPN 559 ++ S Q + Q PG P + P ++ P+ +VR + P+ Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297 Query: 560 LSRVIW--VKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEAS 617 L ++ P PG P +++P ++ P P +P G + + Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK------SQPGPAKPPAQPS-GLTKPLAQQPGTVK 350 Query: 618 PAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPG--------PGW 669 P +PP + + P+ Q GP +P + S + G + PG PG Sbjct: 351 PPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407 Query: 670 AGSPKTEKEKGSSWRNWPG---EAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQE 726 A P + PG AKA + VQ PGP + + G G++ + Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467 Query: 727 KPASSL 732 KP S L Sbjct: 468 KPPSQL 473 Score = 43.5 bits (101), Expect = 8e-04 Identities = 142/687 (20%), Positives = 219/687 (31%), Gaps = 121/687 (17%) Query: 97 SPHSSGAMPG-SSLGSPPTI-------PGEAFPVSEH-------HQHSDLTAPPNSPTG- 140 S S PG +L PP + PG A P ++ Q L +P +P Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437 Query: 141 ----HHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS 196 P P IP+ + G PT P + P A P A P S Sbjct: 438 KTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496 Query: 197 SHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQP---LPSTHRDPGCKGH 253 + PS K PP G + P S G P P S++P PS + + Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKP-SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555 Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ------RDGKF-----CDC 302 K + + QP + ++ C +T + F C Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615 Query: 303 CYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVD 362 C G N P + TE++E L ++ GG L +P P Sbjct: 616 TVCSLCGFNPNP------HLTEVKEWLCLNCQMKR----ALGGDLAPVPSSP-------- 657 Query: 363 ELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARER 422 +PK+ + A K + ++ + A KQ S+ P P + Sbjct: 658 ---------QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----DLSKAPEPKKPP 704 Query: 423 LLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSL 482 L VK + S A P+ S+ Sbjct: 705 PL------------------------VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740 Query: 483 PPSN----LSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVR 538 P ++ +QP + + L S P AE + P T+ Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 539 GPPPGIVPENGLVRRLNT--VP---NLSRVIWVKTPKPGYPSSEEPSSKEV-PSCKQELP 592 P P V ++ +P + S++I PG PSSE K+V P K+E P Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKII----SHPG-PSSESKGQKQVDPVQKKEEP 855 Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGS 652 + + P+ + K S P PRP A VP+ + Q P++ R L +GS Sbjct: 856 KKAQTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPTPQ-QSPKPQEQSRRFSL-NLGS 911 Query: 653 CAEAGEGSRGSRPGP-------GWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705 +A + S+ + P G+ S ++ S PG Q P P Sbjct: 912 ITDAPK-SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970 Query: 706 ARPQSLPQGKGRSRRSRNKQEKPASSL 732 ++P P +G + + PA S+ Sbjct: 971 SQP---PTSQGPPKSTGQAPPAPAKSI 994 Score = 32.0 bits (71), Expect = 2.3 Identities = 53/193 (27%), Positives = 67/193 (34%), Gaps = 30/193 (15%) Query: 79 DWDPSSFLSAHKLSGLWNSPHSSGAM-----PGSSL--GSPPTIPGEAFPVSEHHQHS-D 130 D PSS ++ L + +SG P S L GSP A P S D Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400 Query: 131 LTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA------- 183 ++A P P P P P PP P L P T P + VA Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453 Query: 184 ----AATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ 239 A T T +S+ LP T + PP S SG H P PP + + Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513 Query: 240 P----LPSTHRDP 248 P LP+T + P Sbjct: 2514 PVIPQLPTTTQKP 2526 Score = 30.4 bits (67), Expect = 6.7 Identities = 35/130 (26%), Positives = 43/130 (33%), Gaps = 11/130 (8%) Query: 112 PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPH-PHLLPTTPA 170 P IP + P + Q P S + P+ I S P G P P P T Sbjct: 216 PKPIPKQQGPGRDPLQQD---GTPKSISSQQPEK---IKSQPPGTGKPIQGPTQTPQTDH 269 Query: 171 APFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSG 230 A P Q A G LPS S P ++ P P P + G S Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP----GKPPAQQPGHEKSQ 325 Query: 231 PLLPPPSSQP 240 P P +QP Sbjct: 326 PGPAKPPAQP 335 Score = 30.0 bits (66), Expect = 8.7 Identities = 55/248 (22%), Positives = 75/248 (30%), Gaps = 34/248 (13%) Query: 9 LGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSS 68 L E+ W+C +C+ +R G + A S K+ S S SS +S Sbjct: 629 LTEVKEWLCLNCQM-----KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683 Query: 69 SSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH 128 D P LS +P P L PT+ G ++ Sbjct: 684 PKK-------DAAPKQDLS--------KAPEPKKPPP---LVKQPTLHGSPSAKAKQPPE 725 Query: 129 SDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAP 188 +D + P P PS PS P P P P +A T P Sbjct: 726 ADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 189 HTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTHRDP 248 P S + P LK S P +G +P P+S +H P Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836 Query: 249 G--CKGHK 254 KG K Sbjct: 837 SSESKGQK 844 Score = 30.0 bits (66), Expect = 8.7 Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 25/167 (14%) Query: 577 EEPSSKEVPSCKQEL-PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQV 635 E K+ S QE P P P++ K + + K P P +P AK Sbjct: 1197 ESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK--T 1254 Query: 636 AGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQ 695 + P++ L +V E EG +PKT +E G PQ Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLEGRV----------APKTVQEGKQPQTKMEGLPSGTPQ 1304 Query: 696 E------------QESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730 +E QPP A+P + GK ++ + +K + +S Sbjct: 1305 SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 54.3 bits (129), Expect = 4e-07 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 28/199 (14%) Query: 65 SSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP-PTIPGEAFPVS 123 SS + S P G PS + G + G++ S L S P P + Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 124 EHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA 183 D PP P G+ P H + PP + P P+ P P+ +S+ P Sbjct: 256 PSRALDDKPPPPPPPVGNRPS------IHREAVPPPPPQNNKPPVPSTPRPSASSQAP-P 308 Query: 184 AATAPHTPGPC----------QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLL 233 P PGP ++ LP ++ L PP P G SGPL Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-----PSPGR-----SGPLP 358 Query: 234 PPPSSQPLPSTHRDPGCKG 252 PPPS +P P PG G Sbjct: 359 PPPSERPPPPVRDPPGRSG 377 Score = 39.3 bits (90), Expect = 0.014 Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 35/177 (19%) Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535 +P P P N +P I+ + P PQN+ P P P + P PP Sbjct: 263 KPPPPPPPVGN-------RPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPP 313 Query: 536 EVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT---PKPGY------PSSEEPSS--KEV 584 GPPP + P + +P + + T P PG P SE P ++ Sbjct: 314 SRPGPPP-LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372 Query: 585 PSCKQEL--PEPVSSGGK--------PQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631 P L P PVS G PQ R G + +S PRPP + PSA Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS----GPRPPLPPDRPSA 425 Score = 30.8 bits (68), Expect = 5.1 Identities = 49/168 (29%), Positives = 56/168 (33%), Gaps = 42/168 (25%) Query: 111 SPPTIPGEAFPVSEHHQHS---------------DLTAPPNSPTGHHPQPASLIPSHPSS 155 SPP+ PG FPV S D+ + P+S P I S P + Sbjct: 142 SPPSGPGR-FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200 Query: 156 FGSPP------HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSH-------LPST 202 GSPP P PT P PFP A P SS LP T Sbjct: 201 RGSPPVPGGPRQPSPGPTPP--PFPGNRG---TALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 203 SMPLL--KMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ--PLPSTHR 246 L K PPP P H PPP + P+PST R Sbjct: 256 PSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 54.3 bits (129), Expect = 4e-07 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 28/199 (14%) Query: 65 SSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP-PTIPGEAFPVS 123 SS + S P G PS + G + G++ S L S P P + Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 124 EHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVA 183 D PP P G+ P H + PP + P P+ P P+ +S+ P Sbjct: 256 PSRALDDKPPPPPPPVGNRPS------IHREAVPPPPPQNNKPPVPSTPRPSASSQAP-P 308 Query: 184 AATAPHTPGPC----------QSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLL 233 P PGP ++ LP ++ L PP P G SGPL Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-----PSPGR-----SGPLP 358 Query: 234 PPPSSQPLPSTHRDPGCKG 252 PPPS +P P PG G Sbjct: 359 PPPSERPPPPVRDPPGRSG 377 Score = 39.3 bits (90), Expect = 0.014 Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 35/177 (19%) Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535 +P P P N +P I+ + P PQN+ P P P + P PP Sbjct: 263 KPPPPPPPVGN-------RPSIHREAVPPP--PPQNNKPPVPSTPRPSASSQAPPPPPPP 313 Query: 536 EVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKT---PKPGY------PSSEEPSS--KEV 584 GPPP + P + +P + + T P PG P SE P ++ Sbjct: 314 SRPGPPP-LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372 Query: 585 PSCKQEL--PEPVSSGGK--------PQKGKRQGSQAKKSEASPAPRPPASLEVPSA 631 P L P PVS G PQ R G + +S PRPP + PSA Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS----GPRPPLPPDRPSA 425 Score = 30.8 bits (68), Expect = 5.1 Identities = 49/168 (29%), Positives = 56/168 (33%), Gaps = 42/168 (25%) Query: 111 SPPTIPGEAFPVSEHHQHS---------------DLTAPPNSPTGHHPQPASLIPSHPSS 155 SPP+ PG FPV S D+ + P+S P I S P + Sbjct: 142 SPPSGPGR-FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHN 200 Query: 156 FGSPP------HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSH-------LPST 202 GSPP P PT P PFP A P SS LP T Sbjct: 201 RGSPPVPGGPRQPSPGPTPP--PFPGNRG---TALGGGSIRQSPLSSSSPFSNRPPLPPT 255 Query: 203 SMPLL--KMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQ--PLPSTHR 246 L K PPP P H PPP + P+PST R Sbjct: 256 PSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 53.1 bits (126), Expect = 1e-06 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%) Query: 60 SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116 + S+ S+ S + P G P L A L P G P +S G P T P Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335 Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176 A+P H+ L P + QP P P+ P H PTTP PA Sbjct: 336 AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 387 Query: 177 ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 P A PH GP S + P P HP S H PL P Sbjct: 388 ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 438 Query: 237 SSQPLPSTHRDP 248 SQPLPS+ P Sbjct: 439 QSQPLPSSPAQP 450 Score = 45.4 bits (106), Expect = 2e-04 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%) Query: 45 SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95 S S+S D+ S + S+S S P N D D S+ L A + Sbjct: 133 SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 192 Query: 96 NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148 +P S A PG+ L +P PT A P S P +PT H Q +L Sbjct: 193 VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252 Query: 149 IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172 P P S PPHP L P T P+AP Sbjct: 253 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312 Query: 173 -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205 P QAS+ T+P P S LP++ +MP Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372 Query: 206 LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253 +K PP P P + H SGP L PPP+ +PL STH P Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 432 Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294 + LP GL + ++ +S + HQ Sbjct: 433 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473 Score = 45.4 bits (106), Expect = 2e-04 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135 P + AMP + PPT P P + H+H ++L PP Sbjct: 365 PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422 Query: 136 -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178 + P HP P L+P PSS PP LP PA AP P A Sbjct: 423 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482 Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238 V P TP C PSTS P P + PCS G SG + SS Sbjct: 483 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 531 Query: 239 QPLPS 243 PLP+ Sbjct: 532 CPLPT 536 Score = 41.2 bits (95), Expect = 0.004 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%) Query: 24 MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83 + ED R +GR A S S K+++ + +SS S+ + D + + Sbjct: 48 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107 Query: 84 SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117 S+ K S P+S G S S P+IP Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 167 Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175 E+ S Q PP +PTG P P+S P G+P P PT A P Sbjct: 168 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 221 Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234 Q S A P P P +H+ + PP HP P Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 268 Query: 235 PPSSQPLPSTHRDPGCKGH 253 P QPL + P H Sbjct: 269 HPPLQPLTGSAGQPSAPSH 287 Score = 31.2 bits (69), Expect = 3.9 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%) Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449 +KK+ + + R SG P A D + + V +E + + Sbjct: 34 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 90 Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506 K + R V + +++ S + E P S PS G S +N + S Sbjct: 91 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 148 Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565 Q++ +P P+P E ++ + PP + G+ ++ P + + Sbjct: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 208 Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622 P P P P++ + P+ Q PV P +Q + A + P+P P Sbjct: 209 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 262 Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682 P PS P P + P GS + S P G G P Sbjct: 263 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 299 Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742 P +A P +Q PGP +P LP + + A + LP Sbjct: 300 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 351 Query: 743 GVEMDETDRE 752 ++ + RE Sbjct: 352 ALQSQQPPRE 361 Score = 30.8 bits (68), Expect = 5.1 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%) Query: 269 EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328 E D+GL + + RS + S+ G PA+P R + I E Sbjct: 7 EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 51 Query: 329 LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388 +RS G A D E + + KV A + Sbjct: 52 IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 89 Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443 LK ++++ ++A++ ++A+R S + RP E + VN SS + Sbjct: 90 LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 148 Query: 444 EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495 +I + + + S + DS+ +++ + +P +L PS+ + Q P Sbjct: 149 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 208 Query: 496 DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536 S + GSP QAP +P P A + PHPP Sbjct: 209 TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 264 Query: 537 VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594 P P + P G + + + + + P PG S + + P Q LP Sbjct: 265 HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 323 Query: 595 VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640 S G P Q Q + + P PPA L +P K P Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 380 Query: 641 PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696 P L P+ G S + P A P + P + PQ Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 440 Query: 697 Q----ESVQPPGPARPQSLP 712 Q QPPG + Q+LP Sbjct: 441 QPLPSSPAQPPGLTQSQNLP 460 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 53.1 bits (126), Expect = 1e-06 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%) Query: 60 SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116 + S+ S+ S + P G P L A L P G P +S G P T P Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176 A+P H+ L P + QP P P+ P H PTTP PA Sbjct: 890 AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 941 Query: 177 ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 P A PH GP S + P P HP S H PL P Sbjct: 942 ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 992 Query: 237 SSQPLPSTHRDP 248 SQPLPS+ P Sbjct: 993 QSQPLPSSPAQP 1004 Score = 45.4 bits (106), Expect = 2e-04 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%) Query: 45 SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95 S S+S D+ S + S+S S P N D D S+ L A + Sbjct: 687 SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 746 Query: 96 NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148 +P S A PG+ L +P PT A P S P +PT H Q +L Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806 Query: 149 IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172 P P S PPHP L P T P+AP Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866 Query: 173 -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205 P QAS+ T+P P S LP++ +MP Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 206 LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253 +K PP P P + H SGP L PPP+ +PL STH P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986 Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294 + LP GL + ++ +S + HQ Sbjct: 987 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027 Score = 45.4 bits (106), Expect = 2e-04 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135 P + AMP + PPT P P + H+H ++L PP Sbjct: 919 PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976 Query: 136 -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178 + P HP P L+P PSS PP LP PA AP P A Sbjct: 977 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036 Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238 V P TP C PSTS P P + PCS G SG + SS Sbjct: 1037 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 1085 Query: 239 QPLPS 243 PLP+ Sbjct: 1086 CPLPT 1090 Score = 41.2 bits (95), Expect = 0.004 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%) Query: 24 MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83 + ED R +GR A S S K+++ + +SS S+ + D + + Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 84 SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117 S+ K S P+S G S S P+IP Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 721 Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175 E+ S Q PP +PTG P P+S P G+P P PT A P Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 775 Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234 Q S A P P P +H+ + PP HP P Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 822 Query: 235 PPSSQPLPSTHRDPGCKGH 253 P QPL + P H Sbjct: 823 HPPLQPLTGSAGQPSAPSH 841 Score = 31.2 bits (69), Expect = 3.9 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%) Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449 +KK+ + + R SG P A D + + V +E + + Sbjct: 588 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 644 Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506 K + R V + +++ S + E P S PS G S +N + S Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 702 Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565 Q++ +P P+P E ++ + PP + G+ ++ P + + Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762 Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622 P P P P++ + P+ Q PV P +Q + A + P+P P Sbjct: 763 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 816 Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682 P PS P P + P GS + S P G G P Sbjct: 817 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 853 Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742 P +A P +Q PGP +P LP + + A + LP Sbjct: 854 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905 Query: 743 GVEMDETDRE 752 ++ + RE Sbjct: 906 ALQSQQPPRE 915 Score = 30.8 bits (68), Expect = 5.1 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%) Query: 269 EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328 E D+GL + + RS + S+ G PA+P R + I E Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 605 Query: 329 LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388 +RS G A D E + + KV A + Sbjct: 606 IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 643 Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443 LK ++++ ++A++ ++A+R S + RP E + VN SS + Sbjct: 644 LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 702 Query: 444 EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495 +I + + + S + DS+ +++ + +P +L PS+ + Q P Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762 Query: 496 DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536 S + GSP QAP +P P A + PHPP Sbjct: 763 TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 818 Query: 537 VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594 P P + P G + + + + + P PG S + + P Q LP Sbjct: 819 HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 877 Query: 595 VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640 S G P Q Q + + P PPA L +P K P Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 934 Query: 641 PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696 P L P+ G S + P A P + P + PQ Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994 Query: 697 Q----ESVQPPGPARPQSLP 712 Q QPPG + Q+LP Sbjct: 995 QPLPSSPAQPPGLTQSQNLP 1014 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 53.1 bits (126), Expect = 1e-06 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 20/192 (10%) Query: 60 SSSSSSSSSSSSSCPGNSGDWDPSSF-LSAHKLSGLWNSPHSSGAMPGSSLGSPP--TIP 116 + S+ S+ S + P G P L A L P G P +S G P T P Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 117 GEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQ 176 A+P H+ L P + QP P P+ P H PTTP PA Sbjct: 890 AAAYP------HTSLQLPASQSALQSQQPPREQPLPPAPLAMP-HIKPPPTTPIPQLPA- 941 Query: 177 ASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPP 236 P A PH GP S + P P HP S H PL P Sbjct: 942 ----PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-----PPPLQLMP 992 Query: 237 SSQPLPSTHRDP 248 SQPLPS+ P Sbjct: 993 QSQPLPSSPAQP 1004 Score = 45.4 bits (106), Expect = 2e-04 Identities = 84/341 (24%), Positives = 111/341 (32%), Gaps = 91/341 (26%) Query: 45 SCKSQSCGDDSHSSSSSSSSSSSSSSSSCPG---NSGDWDPSS---FLSAHK---LSGLW 95 S S+S D+ S + S+S S P N D D S+ L A + Sbjct: 687 SSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG 746 Query: 96 NSPHSSGAMPGS-SLGSP-PTIPGEAFPVSEHHQHSDLTAPPNSPTG-----HHPQPASL 148 +P S A PG+ L +P PT A P S P +PT H Q +L Sbjct: 747 VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806 Query: 149 IPSHPSSFGSPPHPH----LLPTT-----PAAP--------------------------- 172 P P S PPHP L P T P+AP Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866 Query: 173 -------FPAQASECPVAAATAPHTPGPCQSSHLPST--------------------SMP 205 P QAS+ T+P P S LP++ +MP Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 206 LLKMPP--PFSGCSHPCSGHCGGHCSGP--------LLPPPSSQPLP--STHRDPGCKGH 253 +K PP P P + H SGP L PPP+ +PL STH P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986 Query: 254 KFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQ 294 + LP GL + ++ +S + HQ Sbjct: 987 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027 Score = 45.4 bits (106), Expect = 2e-04 Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 52/185 (28%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQH-------------SDLTAPP--------- 135 P + AMP + PPT P P + H+H ++L PP Sbjct: 919 PPAPLAMP--HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976 Query: 136 -NSPTGHHPQPASLIPSH---PSSFGSPP---HPHLLPTTPA----------APFPAQAS 178 + P HP P L+P PSS PP LP PA AP P A Sbjct: 977 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036 Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSS 238 V P TP C PSTS P P + PCS G SG + SS Sbjct: 1037 HPFVPGGPPPITPPTC-----PSTSTP---PAGPGTSAQPPCS---GAAASGGSIAGGSS 1085 Query: 239 QPLPS 243 PLP+ Sbjct: 1086 CPLPT 1090 Score = 41.2 bits (95), Expect = 0.004 Identities = 61/259 (23%), Positives = 83/259 (32%), Gaps = 48/259 (18%) Query: 24 MEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWDPS 83 + ED R +GR A S S K+++ + +SS S+ + D + + Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 84 SFLSAHKLSGLWNS-PHSSGAMPGSSLGS---------------------PPTIP----G 117 S+ K S P+S G S S P+IP Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDN 721 Query: 118 EAFPVSEHHQHSDLTAPP--NSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPA 175 E+ S Q PP +PTG P P+S P G+P P PT A P Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------GTPQLPTPGPTPSATAVPP 775 Query: 176 QASECPVAAATAPHTP-GPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLP 234 Q S A P P P +H+ + PP HP P Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-------------P 822 Query: 235 PPSSQPLPSTHRDPGCKGH 253 P QPL + P H Sbjct: 823 HPPLQPLTGSAGQPSAPSH 841 Score = 31.2 bits (69), Expect = 3.9 Identities = 74/370 (20%), Positives = 123/370 (33%), Gaps = 49/370 (13%) Query: 390 KKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTV 449 +KK+ + + R SG P A D + + V +E + + Sbjct: 588 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS---NDSKAETVKKSAKKVKEEASSPL 644 Query: 450 KDSIRASFSVCELSMDSNGFSKEGAAEPE---PQSLPPSNLSGSSEQQPDINLDLSPLTL 506 K + R V + +++ S + E P S PS G S +N + S Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PSEGEGESSDSRSVNDEGSSDPK 702 Query: 507 GSPQNHTLQAPGEPAPPWAEMRGPHPPWTEV-RGPPPGIVPENGLVRRLNTVPNLSRVIW 565 Q++ +P P+P E ++ + PP + G+ ++ P + + Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762 Query: 566 VKTPKPG---YPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622 P P P P++ + P+ Q PV P +Q + A + P+P P Sbjct: 763 TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV-----PHTHIQQ-APALHPQRPPSPHP 816 Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682 P PS P P + P GS + S P G G P Sbjct: 817 PPH---PS-------PHPPLQ----PLTGSAGQPSAPSHAQPPLHG-QGPPG-------- 853 Query: 683 WRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMD 742 P +A P +Q PGP +P LP + + A + LP Sbjct: 854 ----PHSLQAGPL----LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905 Query: 743 GVEMDETDRE 752 ++ + RE Sbjct: 906 ALQSQQPPRE 915 Score = 30.8 bits (68), Expect = 5.1 Identities = 104/500 (20%), Positives = 163/500 (32%), Gaps = 102/500 (20%) Query: 269 EADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREK 328 E D+GL + + RS + S+ G PA+P R + I E Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRS--------------GRKKQPASPDGRT-SPINED 605 Query: 329 LRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHK 388 +RS G A D E + + KV A + Sbjct: 606 IRS----------------SGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP------ 643 Query: 389 LKKKEKEKAQLAAEALKQANRVSGSREP-----RPARERLLEWPDRELDRVNSFLSSRLQ 443 LK ++++ ++A++ ++A+R S + RP E + VN SS + Sbjct: 644 LKSNKRQREKVASDT-EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK 702 Query: 444 EIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLP--------PSNLSGSSEQQP 495 +I + + + S + DS+ +++ + +P +L PS+ + Q P Sbjct: 703 DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762 Query: 496 DINLDLSPLTL---GSPQNHTLQAPGEPAPPWAEMR----------------GPHPPWTE 536 S + GSP QAP +P P A + PHPP Sbjct: 763 TPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP--P 818 Query: 537 VRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQE--LPEP 594 P P + P G + + + + + P PG S + + P Q LP Sbjct: 819 HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQ 877 Query: 595 VSSGGKP--------------QKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQ 640 S G P Q Q + + P PPA L +P K P Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP---PTT 934 Query: 641 PGRVLELPKVGSCAEAGEG----SRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQE 696 P L P+ G S + P A P + P + PQ Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994 Query: 697 Q----ESVQPPGPARPQSLP 712 Q QPPG + Q+LP Sbjct: 995 QPLPSSPAQPPGLTQSQNLP 1014 >gi|13128980 proline rich 14 [Homo sapiens] Length = 585 Score = 53.1 bits (126), Expect = 1e-06 Identities = 62/211 (29%), Positives = 83/211 (39%), Gaps = 24/211 (11%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFG 157 P A+P L SPPT P A + S L P SP G P S + S SF Sbjct: 203 PFQPSALPADPLESPPTAPDPALELPSTPPPSSLLRPRLSPWGLAPLFRS-VRSKLESFA 261 Query: 158 S---PPHPHLLPTTPAAPFP-------AQASECPVAAATAPHTP-GPCQSSHLPSTSMPL 206 P+ P P+ P ++A + A TA +P P + + P Sbjct: 262 DIFLTPNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPA 321 Query: 207 LKMPPPFSGCSHPCS--GHCG-GHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQ 263 L +P P G S+ C G G G C+ P PP S+P P H G A Sbjct: 322 L-LPKPSLGRSYSCPDLGPPGPGTCTWPPAPPQPSRPRPRRHTVGG------GEMARAPP 374 Query: 264 LPQPCEADE--GLGEEEDSSSERSSCTSSST 292 P+PC E LG S S +SC+S+++ Sbjct: 375 PPRPCLRKEVFPLGGVGASPSLTTSCSSTAS 405 >gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo sapiens] Length = 1833 Score = 52.8 bits (125), Expect = 1e-06 Identities = 60/190 (31%), Positives = 73/190 (38%), Gaps = 35/190 (18%) Query: 510 QNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTP 569 Q+ Q P +P PP E G W GPPP P G VR N+ W P Sbjct: 819 QHQQQQPPQQPPPPQPEASGS---WG---GPPP---PPPGNVRPSNSS-------WSSGP 862 Query: 570 KPGYPSSEEPSSKEVP-----SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRP 622 +P P EEPS E P S K ++ + S+ G P K K S+ PAPR Sbjct: 863 QPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPRE 922 Query: 623 PASLEVP--SAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKG 680 P +L P S V P P G+ A GE + S PGW G Sbjct: 923 P-NLPTPMTSKSASVWSKSTP----PAPDNGTSA-WGEPNESS---PGW-GEMDDTGAST 972 Query: 681 SSWRNWPGEA 690 + W N P A Sbjct: 973 TGWGNTPANA 982 Score = 30.4 bits (67), Expect = 6.7 Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 28/156 (17%) Query: 567 KTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQ--------------AK 612 + P G+ S + +EV K E SS KP G +G Q A Sbjct: 736 RQPNQGWSSGKNGWGEEVDQTKNSNWE--SSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793 Query: 613 KSEASPAPRPPASLEV---PSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGW 669 K R PA E P++ + +QP + P+ GS G P P Sbjct: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQ-----PEASGSWGGPPPP-- 846 Query: 670 AGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGP 705 P + SSW + P A + +E + P P Sbjct: 847 --PPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880 >gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] Length = 1243 Score = 52.0 bits (123), Expect = 2e-06 Identities = 55/163 (33%), Positives = 68/163 (41%), Gaps = 46/163 (28%) Query: 95 WNSPHSSGAMPGSSL--GSP-----PTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPAS 147 W + +S + PG+ L G+P P PG FP+ T+PP P+ P P S Sbjct: 797 WTAFSTSSSSPGTPLSPGNPFSPGTPISPGPIFPI---------TSPPCHPS---PSPFS 844 Query: 148 LIPSHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLL 207 I S SS P PH PT+ PF + E PV + C S LP+TS Sbjct: 845 PISSQVSS---NPSPH--PTSSPLPFSSSTPEFPVPLS-------QCPWSSLPTTS---- 888 Query: 208 KMPPPFS-GCSHPCSGHCGGHCSGPLLPP-PSSQPLPSTHRDP 248 PP FS CS S P PP PS+ PST P Sbjct: 889 --PPTFSPTCSQVT-------LSSPFFPPCPSTSSFPSTTAAP 922 Score = 37.7 bits (86), Expect = 0.042 Identities = 50/194 (25%), Positives = 68/194 (35%), Gaps = 24/194 (12%) Query: 50 SCGDDSHSSSSSSSSSSSSSSSSCPGNSGDWD------PSSF---LSAHKLSGLWNSPHS 100 S H +SS SSS+ P + W P +F S LS + P Sbjct: 851 SSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCP 910 Query: 101 SGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAP-PNSPTGHHPQPASLIPSHP------ 153 S + S+ +P AF ++ L +P P + P P S +PS P Sbjct: 911 STSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVA 970 Query: 154 SSFGSPPHPHLLPTT------PAAPFPAQASECPVAAATAPHTPGPCQ--SSHLPSTSMP 205 P PH PA P P +A P++ P G Q SS P+ +P Sbjct: 971 PGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLP 1030 Query: 206 LLKMPPPFSGCSHP 219 L P SG P Sbjct: 1031 LQPTSPTLSGSPKP 1044 Score = 36.6 bits (83), Expect = 0.093 Identities = 78/295 (26%), Positives = 105/295 (35%), Gaps = 43/295 (14%) Query: 410 VSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGF 469 +S EP P + PD + + S S E ++ S +S LS N F Sbjct: 762 LSPQEEPAPLPALPVPLPDPSNEELQSSTSL---EHRSWTAFSTSSSSPGTPLS-PGNPF 817 Query: 470 SKEGAAEPEPQ---SLPPSNLSGS--SEQQPDINLDLSPLTLGSPQNHTLQAPGEPAP-- 522 S P P + PP + S S S ++ + SP SP + P P P Sbjct: 818 SPGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLS 877 Query: 523 --PWAEMRGPHPPW-------TEVRGP--PPGIVPENGLVRRLNTVPNLS-------RVI 564 PW+ + PP + P PP P P LS V+ Sbjct: 878 QCPWSSLPTTSPPTFSPTCSQVTLSSPFFPP--CPSTSSFPSTTAAPLLSLASAFSLAVM 935 Query: 565 WVK----TPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAP 620 V +P PG S+ P + P LP PV+ GG Q+ + +SEASP P Sbjct: 936 TVAQSLLSPSPGL-LSQSPPAPPSPLPSLPLPPPVAPGG--QESPSPHTAEVESEASPPP 992 Query: 621 RPPASLEVPSAKGQVAG-PKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPK 674 P E A G P+ GR +V S E E P +GSPK Sbjct: 993 ARPLPGEARLAPISEEGKPQLVGRF----QVTSSKEPAEPLPLQPTSPTLSGSPK 1043 Score = 32.7 bits (73), Expect = 1.3 Identities = 37/165 (22%), Positives = 65/165 (39%), Gaps = 24/165 (14%) Query: 592 PEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAK---GQVAGPKQPGRVLELP 648 P P+ + G+P+ G +A++ PRP +S + G ++ P P Sbjct: 25 PPPLGTAGQPRLGPPP-RRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSWSLPASPAPDP 83 Query: 649 KVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWP----GEAKARPQEQESVQPPG 704 + + PGP + P +++ +W E ARP+ +S PG Sbjct: 84 P--------DPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAAEDSARPELPDSAVGPG 135 Query: 705 PARPQSLPQGKGRSRRSRNKQEKP-------ASSLDDVFLPKDMD 742 P +P+ RR R ++EK A+S D +L D++ Sbjct: 136 SREPLRVPEAVALERR-REQEEKEDMETQAVATSPDGRYLKFDIE 179 Score = 31.6 bits (70), Expect = 3.0 Identities = 36/140 (25%), Positives = 47/140 (33%), Gaps = 32/140 (22%) Query: 574 PSSEEPSSKEVPSCKQELP-----EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEV 628 P + E S+ P + LP P+S GKPQ R + K A P P P S Sbjct: 979 PHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQPTS--- 1035 Query: 629 PSAKGQV-------------------AGPKQPGRVLELPKVGSCAEAG---EGSRGSRPG 666 P+ G GP+ + E + AG EG G P Sbjct: 1036 PTLSGSPKPSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGLGAGVEEEGDDGKEPQ 1095 Query: 667 PGWAGSPKTEKEKGSSWRNW 686 G GSP+ W N+ Sbjct: 1096 VG--GSPQPLSHPSPVWMNY 1113 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 52.0 bits (123), Expect = 2e-06 Identities = 79/348 (22%), Positives = 132/348 (37%), Gaps = 55/348 (15%) Query: 369 NSTEPKVPN-SARAAKRARHKLKKKEKEKAQLAAEALKQANR-------VSGSREPRPAR 420 NS E P SA A ++ + +E+ + A + L + R + GS+ + Sbjct: 591 NSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650 Query: 421 ERLLEWPDRE-LDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEP-- 477 + R+ LD + ++++ +N + +A + S+E A P Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAA----------SEEAAFPPVV 700 Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT-E 536 E + + S +SG+ E+ + + S ++ +P A GP PP T Sbjct: 701 EDEEMEASGVSGNEEEMVE---EAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLG 757 Query: 537 VRGPPPG--IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEP 594 GPPPG P + P S TP P PS P VP K+E E Sbjct: 758 ADGPPPGPPTPPPEDIPAPTEPTP-ASEATGAPTPPPAPPSPSAPPPV-VP--KEEKEEE 813 Query: 595 VSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLEL---PKVG 651 ++ ++G+ Q +PPA+ E+ G+ P + E P G Sbjct: 814 TAAAPPVEEGEEQ-------------KPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKG 860 Query: 652 SCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQES 699 AEA E + G+ K EK++G S R ++ PQ+ +S Sbjct: 861 KDAEAAEATA--------EGALKAEKKEGGSGRATTAKSSGAPQDSDS 900 Score = 35.8 bits (81), Expect = 0.16 Identities = 68/291 (23%), Positives = 110/291 (37%), Gaps = 47/291 (16%) Query: 16 VCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSC-GDDSHSSSSSSSSSSSSSSSSCP 74 V C + EE + G++ A + + + K++ G ++++ SS + S SS Sbjct: 845 VKSECTEEAEEGPAK-GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSAT 903 Query: 75 GNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPT--IPGEAFPVSEHHQHSDLT 132 ++ + D + ++L SP S P G P P + + + Q + Sbjct: 904 CSADEVDEAEGGDKNRLL----SPRPSLLTP---TGDPRANASPQKPLDLKQLKQRAAAI 956 Query: 133 APPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLP----------------TTPAAPFPAQ 176 P H P P+ P+ PP +L P +PA P + Sbjct: 957 PPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKE 1016 Query: 177 ASE---CPVAAATAPHTPG--PCQSSHLPSTSMP--LLKMPPPF---SGCSHPCSGH--- 223 A + P AA A PG PC +S LP P ++K P S S+ GH Sbjct: 1017 AEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1076 Query: 224 CGGH-CSGPLLPPP----SSQPLPSTHRDPGCKGHKFA--HSGLACQLPQP 267 G H + P+LP P + PL S+ + P + G++ QL P Sbjct: 1077 LGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVP 1127 Score = 33.5 bits (75), Expect = 0.79 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 17/111 (15%) Query: 112 PPTIPGEAFPVS-------EHHQHSDLTAPPNSPTGHHPQPASLI--------PSHPSSF 156 PP + E S E + ++ T +S T P P + P P++ Sbjct: 697 PPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATL 756 Query: 157 GSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLL 207 G+ P PT P PA P + AT TP P S PS P++ Sbjct: 757 GADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS--PSAPPPVV 805 Score = 30.0 bits (66), Expect = 8.7 Identities = 35/168 (20%), Positives = 59/168 (35%), Gaps = 28/168 (16%) Query: 16 VCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGDDSHSSSSSSSSSSS--SSSSSC 73 + Q + ME++ ++ + S + D+ +S S + + + Sbjct: 665 ILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEAT 724 Query: 74 PGNSGDWD--PSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDL 131 NS D + PS A K +G +G P ++LG+ PG Sbjct: 725 VNNSSDTESIPSPHTEAAKDTG------QNGPKPPATLGADGPPPG-------------- 764 Query: 132 TAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQASE 179 PP P P P P+ ++ P P P +P+AP P E Sbjct: 765 --PPTPPPEDIPAPTEPTPASEATGAPTPPP--APPSPSAPPPVVPKE 808 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 52.0 bits (123), Expect = 2e-06 Identities = 87/392 (22%), Positives = 143/392 (36%), Gaps = 61/392 (15%) Query: 372 EPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDREL 431 E K P A++ ++A+ +K++ K A+ + ++A + + P A+ E E Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE----EA 646 Query: 432 DRVNSFLSSRLQEIKNT--VKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSG 489 S +E K+ K ++A E + K A PE P + Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP---VKAEAKSPEKAKSPVKEEAK 703 Query: 490 SSEQ--QPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPE 547 S E+ P SP SP + P + P E E + P PE Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE---------EAKSPEKAKSPE 754 Query: 548 NGLVRRLNTVPNLSRVIWVKTPKPGYPSSEE---PSSKEVPSCKQELPEPVSSGGKPQKG 604 ++ + VK+P+ P+ EE P+ K K + E V S P+K Sbjct: 755 K------------AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS---PEKA 799 Query: 605 KRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSR 664 K S K+ +P P EV S + P++ +V E PK +A Sbjct: 800 K---SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV-KVKEPPKKAEEEKA-------- 847 Query: 665 PGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRSRRSRNK 724 +PKTE++K S P + +P+ +E +P +S + K + K Sbjct: 848 -----PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902 Query: 725 -----QEKPAS-SLDDVFLPKDMDGVEMDETD 750 +E PA + + PK+ V E D Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934 Score = 40.8 bits (94), Expect = 0.005 Identities = 86/388 (22%), Positives = 140/388 (36%), Gaps = 70/388 (18%) Query: 372 EPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGSREPRPARERLLEWPDREL 431 E K P A++ +A + K EK K+ + AEA S +E + E+ P +E Sbjct: 659 EAKSPEKAKSPVKA--EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS-PVKEE 715 Query: 432 DRVNSFLSSRLQE-----------IKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQ 480 + S ++E +K K +A ++D + A+ E + Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775 Query: 481 SLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGP-----HPPWT 535 S P++ + P SP SP +AP + P E++ P P Sbjct: 776 S--PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833 Query: 536 EVRGPPPGIVPENGLVRRLNTVPNLSRVIWV---KTPKPGYPSSEEPS------------ 580 +V+ PP E S+ + PKP +EP+ Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893 Query: 581 ------SKEVPSCKQELPE--PVSSGGKPQK----GKRQGSQAKKSEAS-PAPRPPASLE 627 K+VP+ ++E P V KP++ K++ AK E S PA + A+ E Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953 Query: 628 VPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWP 687 K + A K+P E PK + A+ + + P PK EK + SS Sbjct: 954 KKDTKEEKA--KKPE---EKPKTEAKAKEDDKTLSKEP-----SKPKAEKAEKSS----- 998 Query: 688 GEAKARPQEQESVQPPGPARPQSLPQGK 715 +Q+ +PP A +GK Sbjct: 999 ------STDQKDSKPPEKATEDKAAKGK 1020 Score = 38.9 bits (89), Expect = 0.019 Identities = 45/202 (22%), Positives = 83/202 (41%), Gaps = 13/202 (6%) Query: 539 GPPPGIVPENGLVRRLNTVPNLSRVIWVKTP---KPGYPSSEEPSSKEVPSCKQELPEPV 595 GP P +PE L +P++S I VK+ K S +E E + + ++ E V Sbjct: 416 GPIPFSLPEG-----LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470 Query: 596 SSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAE 655 + + + + +G + + E A + P A+ + A P++ + + S AE Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE-EAASPEKEAKSPVKEEAKSPAE 529 Query: 656 AGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP---PGPARPQSLP 712 A + P SP+ K P EAK+ P+++E+ P P + +S Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAEVKSPEKAKSPA 588 Query: 713 QGKGRSRRSRNKQEKPASSLDD 734 + + +S EK S + + Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKE 610 >gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 preproprotein [Homo sapiens] Length = 178 Score = 51.6 bits (122), Expect = 3e-06 Identities = 64/241 (26%), Positives = 83/241 (34%), Gaps = 86/241 (35%) Query: 487 LSGSSEQQPDINLDLSP-LTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPP--G 543 LS + D++ + SP L G+PQ + Q +P +GP PP + +GPPP G Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKP-------QGPPPPPGKPQGPPPQGG 65 Query: 544 IVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPS-----SKEVPSCKQELPEPVSSG 598 P+ P PG P P S P K + P P G Sbjct: 66 NKPQG-------------------PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP--QG 104 Query: 599 GKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGE 658 GKPQ QG +S SP +P GP Q E Sbjct: 105 GKPQGPPAQGGSKSQSARSPPGKP-------------QGPPQQ----------------E 135 Query: 659 GSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPPGPARPQSLPQGKGRS 718 G+ P P G+P+ +PQ + QP GP RP PQG S Sbjct: 136 GNNPQGPPPPAGGNPQ------------------QPQAPPAGQPQGPPRP---PQGGRPS 174 Query: 719 R 719 R Sbjct: 175 R 175 Score = 35.4 bits (80), Expect = 0.21 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 13/148 (8%) Query: 97 SPHSSGAMPGSSLGSPPTIPGEAF-PVSEHHQHSDLTAPPNSPTGHHPQ-PASLIPSHPS 154 +P G+ PP PG+ P + PP P G PQ S P P Sbjct: 35 NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94 Query: 155 SFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHTPG--PCQSSHLPSTSMPLLKMPPP 212 G P P P P PAQ +A + P P P Q + P PPP Sbjct: 95 --GKPQGPPPQGGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP------PPP 145 Query: 213 FSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 G G GP PP +P Sbjct: 146 AGGNPQQPQAPPAGQPQGPPRPPQGGRP 173 Score = 33.5 bits (75), Expect = 0.79 Identities = 39/146 (26%), Positives = 52/146 (35%), Gaps = 34/146 (23%) Query: 586 SCKQELPEPVSSGGKPQ--KGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGR 643 S Q L E VS P G QG + P PP G+ GP G Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPP--------GKPQGPPPQG- 64 Query: 644 VLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPP 703 G +G P PG P + +K S R+ PG+ + PP Sbjct: 65 -------------GNKPQGPPP-PGKPQGPPPQGDKSRSPRSPPGKPQG--------PPP 102 Query: 704 GPARPQSLP-QGKGRSRRSRNKQEKP 728 +PQ P QG +S+ +R+ KP Sbjct: 103 QGGKPQGPPAQGGSKSQSARSPPGKP 128 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 51.6 bits (122), Expect = 3e-06 Identities = 71/276 (25%), Positives = 101/276 (36%), Gaps = 52/276 (18%) Query: 487 LSGSSEQQPDINLDLSPLTL-----------GSPQNHTLQAPGEPA--PPWA--EMRGPH 531 LS + D++ + SP + G+ T PG+P PP + +GP Sbjct: 13 LSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPP 72 Query: 532 PPWTEVRGPPP-------GIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEP---SS 581 P + GPPP G P G + P P+PG P P + Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPG--KPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 130 Query: 582 KEVPSCKQELPE-PVSSGGK------PQKGKRQGSQAKKSEASPAPRP-PASLEVPSAKG 633 + P + PE P GG P+ GK +G + S P P P E P +G Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190 Query: 634 --QVAGPK-QPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEA 690 Q GP +PG+ P G G S+G P PG P+ +G + P Sbjct: 191 GNQSQGPPPRPGKPEGPPPQG-----GNQSQGPPPRPG---KPEGPPSQGGNKPQGPPPH 242 Query: 691 KARPQ------EQESVQPPGPARPQSLPQGKGRSRR 720 +PQ + +PP P RPQ P G ++ Sbjct: 243 PGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQ 278 Score = 33.1 bits (74), Expect = 1.0 Identities = 40/169 (23%), Positives = 55/169 (32%), Gaps = 34/169 (20%) Query: 478 EPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQN-----HTLQAPGEPAPPWAEMRGPHP 532 +P+ PP + S P P G Q+ H + G P + +GP P Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP 199 Query: 533 PWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELP 592 + GPP P+ G N S+ P+PG P P Sbjct: 200 RPGKPEGPP----PQGG---------NQSQ---GPPPRPGKPEGPPSQGGNKP------- 236 Query: 593 EPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQP 641 G P GK QG ++ P PP + P G P+QP Sbjct: 237 ----QGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPG--GNPQQP 279 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 51.2 bits (121), Expect = 4e-06 Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 25/191 (13%) Query: 60 SSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSPPTIPGEA 119 S S S S P S + P L LS SP P +L +P + P EA Sbjct: 492 SPLSPPPEESPLSPPPESSPFSP---LEESPLSPPEESP------PSPALETPLSPPPEA 542 Query: 120 FPVSEHHQHSDLTAPPNS-PTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAAPFPAQAS 178 P+S + S L+ PP PT P+ + L P S SPP P P +P P +AS Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-PEESPMSP----PPEAS 597 Query: 179 ECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPS- 237 +P +P P +S P L PP S S P P+ PPP Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE-------ESPMSPPPEV 650 Query: 238 --SQPLPSTHR 246 PLP R Sbjct: 651 SRLSPLPVVSR 661 Score = 42.4 bits (98), Expect = 0.002 Identities = 65/262 (24%), Positives = 88/262 (33%), Gaps = 36/262 (13%) Query: 471 KEGAAEPEPQSLPPSNLSGS-------SEQQPDINLDLSPLTLGSP-----QNHTLQAPG 518 +E P P+S P S L S S P + LSP SP + L P Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558 Query: 519 EPAP----PWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYP 574 E P P A P PP PPP P ++ P SR+ P P Sbjct: 559 EELPTSPPPEASRLSP-PPEESPMSPPPEESP-------MSPPPEASRLFPPFEESPLSP 610 Query: 575 SSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQ 634 EE P + P P S P ++S SP P +P + Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSP--------PPEESPMSPPPEVSRLSPLP-VVSR 661 Query: 635 VAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARP 694 ++ P + + P+ + E SR S P SP E S P ++ Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSLMSL 718 Query: 695 QEQESVQPPGPARPQSLPQGKG 716 +ES P P PQ P+ +G Sbjct: 719 PLEESPLLPLPEEPQLCPRSEG 740 Score = 39.7 bits (91), Expect = 0.011 Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 44/150 (29%) Query: 116 PGEAFPVSEHHQHSDLTAPPNS-------------PTGHHPQPASLIPSHPSSFGSP--- 159 P E P+S + S L+ PP S P P PA P P SP Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547 Query: 160 --------PHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPP 211 P P LPT+P P +AS +P +P P +S P ++ P Sbjct: 548 PFEESPLSPPPEELPTSP----PPEASRLSPPPEESPMSPPPEESPMSPPPEAS--RLFP 601 Query: 212 PFSGCSHPCSGHCGGHCSGPLLPPPSSQPL 241 PF PL PPP PL Sbjct: 602 PFE--------------ESPLSPPPEESPL 617 Score = 39.3 bits (90), Expect = 0.014 Identities = 60/221 (27%), Positives = 73/221 (33%), Gaps = 61/221 (27%) Query: 101 SGAMPGSS------LGSPPTIPGE-----------AFPVSEHHQHSDLTAPPN-SPTGHH 142 +G++PG L PP +P + A+P+ + T PP SPTG Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206 Query: 143 PQPASLIPSHPSSFGSPPHPHLLPT-----TPAAPFPAQASECP-VAAATAPHTPGPCQS 196 QP L S G P H P P+ P P CP + P +PG Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266 Query: 197 SHLPSTSMPLLKMPPPFS-------------GCSHPCSG----------HCGGHCSGPLL 233 S PLL PPPF G S P G G H G L Sbjct: 2267 ----KASEPLLS-PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321 Query: 234 PPPSSQPLPSTHR----DPGCKGHKFAHSGLACQLPQPCEA 270 P P T R +P G GL Q P P +A Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPG-----LGLRPQEPPPAQA 2357 Score = 38.1 bits (87), Expect = 0.032 Identities = 71/290 (24%), Positives = 101/290 (34%), Gaps = 38/290 (13%) Query: 447 NTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQ-QPDINLDLS--- 502 +T D A + C+ + EP P L + Q +P + L+ Sbjct: 379 DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEM 438 Query: 503 PLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSR 562 PL L P+ L P E +P PP PPP +P + L L +LSR Sbjct: 439 PL-LPPPEESPLSPPPEESPT------SPPPEASRLSPPPEELPASPLPEAL----HLSR 487 Query: 563 VIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRP 622 + P P E P S P P SS P + + + E+ P+P Sbjct: 488 PLEESPLSP--PPEESPLS----------PPPESSPFSPLE---ESPLSPPEESPPSPAL 532 Query: 623 PASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSS 682 L P ++ P + + P+ + E SR S P SP E+ S Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592 Query: 683 WRNWPGEAKA--RPQEQESVQPPGPARPQSLPQGKGRSRRSRNKQEKPAS 730 P EA P E+ + PP P S P SR S ++ P S Sbjct: 593 ----PPEASRLFPPFEESPLSPPPEESPLSPP--PEASRLSPPPEDSPMS 636 Score = 37.7 bits (86), Expect = 0.042 Identities = 50/169 (29%), Positives = 56/169 (33%), Gaps = 21/169 (12%) Query: 98 PHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNS----------PTGHHPQPAS 147 P S A+P SL S P A P S+ S LT P S P P P S Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451 Query: 148 LIPSHPSSFG--SPPHPHLLPTTPAAPFPAQA---SECPVAAATAPHTPGPCQSSH--LP 200 PS P S +P H P P F A + + A GP H +P Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511 Query: 201 STSMPLLKMPP---PFSGCSHPCSGHCGGHCSGPLLPPPSSQP-LPSTH 245 S P P F G P P L PP QP LP H Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH 2560 Score = 37.0 bits (84), Expect = 0.071 Identities = 63/261 (24%), Positives = 87/261 (33%), Gaps = 42/261 (16%) Query: 5 VKNLLGEMPL--WVCQSCRKSME----EDERQTGREHAVAISLSHTSCKSQSCGDDSHSS 58 +K + E+P W C++CR E E SL H K+Q G S Sbjct: 303 LKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQG-GQTIRSV 361 Query: 59 SSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMP------------- 105 + + S S PG++ +P + A G H + P Sbjct: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVA--CQGQPKGGHVTSMQPKEPGPLQCEAKPL 419 Query: 106 ---GSSLGSPPTIP-GEAFPVSEHHQHSDLTAPP-NSPTGHHPQPASLIPSHPSSFGSPP 160 G L P E P+ + S L+ PP SPT P+ + L P P + P Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP-PEELPASP 478 Query: 161 HPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPC 220 P L + P + S +P +P P S P PL PP P Sbjct: 479 LPEALHLSR----PLEESPLSPPPEESPLSPPPESSPFSPLEESPL---SPPEESPPSPA 531 Query: 221 SGHCGGHCSGPLLPPPSSQPL 241 PL PPP + PL Sbjct: 532 -------LETPLSPPPEASPL 545 Score = 37.0 bits (84), Expect = 0.071 Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 23/149 (15%) Query: 111 SPPTIPGEAFPVSEHHQHSDLTAPP-NSPTGHHPQPASLIPSHPSSFGSP--------PH 161 SP + P EA +S + S ++ PP SP P+ + L P S SP P Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674 Query: 162 PHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQS----------SHLPSTSMPLLKMPP 211 P PT+P P +AS +P +P P S LP PLL +P Sbjct: 675 PEESPTSP----PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730 Query: 212 PFSGCSHPCSGHCGGHCSGPLLPPPSSQP 240 C H P L P +P Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759 Score = 35.4 bits (80), Expect = 0.21 Identities = 53/202 (26%), Positives = 68/202 (33%), Gaps = 46/202 (22%) Query: 91 LSGLWNSPHSSGAMPGSSLGSPPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIP 150 LS L + GA S SP P P+S P + T P P ++P Sbjct: 951 LSPLGELEYPFGAKGDSDPESPLAAPILETPISP--------PPEANCTDPEPVPPMILP 1002 Query: 151 SHPSSFGSPPHPHLLPTTPAAPFPAQASECPVAAATAPHT-PGPCQSSHLPSTSMPLLKM 209 P S P P L+ P P Q S + ++ P C LP L + Sbjct: 1003 PSPGSPVGPASPILM-----EPLPPQCSPLLQHSLVPQNSPPSQCSPPALP------LSV 1051 Query: 210 PPPFS------GCS-----HPCSGHCGGHCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHS 258 P P S G S H P L P ++ PLPS D Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD----------- 1100 Query: 259 GLACQLPQPCEADE---GLGEE 277 L+C P P A + GLGE+ Sbjct: 1101 -LSCPAPSPAPALDDFSGLGED 1121 Score = 33.1 bits (74), Expect = 1.0 Identities = 55/211 (26%), Positives = 76/211 (36%), Gaps = 23/211 (10%) Query: 514 LQAPGEPAPPWAEMRGPHPPWTEVRGPPPG--IVPENGLVRRLNTVPNLSRVIWVKTPKP 571 L+ P P PP A P P + P PG + P + ++ P S ++ Sbjct: 978 LETPISP-PPEANCTDPEPVPPMILPPSPGSPVGPASPILME-PLPPQCSPLLQHSL--- 1032 Query: 572 GYPSSEEPSSKEVPSCKQELPEPVSSGGK-----PQKGKRQGSQAKKSEAS-PAPRPPAS 625 P + PS P+ +P P+S GK + + K SE PA P A+ Sbjct: 1033 -VPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091 Query: 626 LEVPSAKGQVAGPKQPGRVLELPKVGSCAE-----AGEGSRGSRPGPGWAGSPKTEKEKG 680 +PS G ++ P P L E G + GS+P PG + KG Sbjct: 1092 SPLPSPMGDLSCP-APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKG 1150 Query: 681 SSWRNWPGE-AKARPQE--QESVQPPGPARP 708 S P E A P E E Q G P Sbjct: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181 Score = 33.1 bits (74), Expect = 1.0 Identities = 64/303 (21%), Positives = 101/303 (33%), Gaps = 81/303 (26%) Query: 462 LSMDSNGFSKEGAAEPEPQSL---PPSNLSGSSEQQPDI----------NLDLSPLTLGS 508 LS DS + +P+P SL PP L G +QQ + L + S Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128 Query: 509 PQNHTLQAPG-----EPAPPWAEMRGPHPPWTE--------VRGPPPGIVPENGL-VRRL 554 H L P +P + GP P E + P PG V ++G + + Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGV 4188 Query: 555 NTVPNLSRV------IWVKTPKPGYPSSEEPSSKEVPSCKQELPE--------------- 593 +P + ++ + K P+ + S ++ + +++L + Sbjct: 4189 GIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGT 4248 Query: 594 ---PVSS--GGKPQKGKRQGSQA---KKSEASPAPRPPASLEVPS---AKGQVAGPKQPG 642 P+ G +PQ G G Q ++ A P P+ P L P + G V GP P Sbjct: 4249 QTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP- 4307 Query: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP 702 P P PK + S P EA+ P + +P Sbjct: 4308 ---------------------TPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346 Query: 703 PGP 705 GP Sbjct: 4347 QGP 4349 Score = 32.3 bits (72), Expect = 1.8 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 33/217 (15%) Query: 476 EPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPPWT 535 EP Q+ P L G QP + PQ LQ G P R P PP Sbjct: 4245 EPGTQTSPLQGLLGC---QPQLG------GFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295 Query: 536 EVRGP--------PPGIVPENGLVRRLNTVPNLSRVIWVK---------TPKPGYPSSEE 578 GP PP P+ +R + +P+ S + + TPKP P+ E Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEP--KRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP 4353 Query: 579 PSSKEVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGP 638 P + P+ Q S G P ++ +K E S P L+ GQV Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL--VPGHLD--QVNGQVVPE 4409 Query: 639 KQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKT 675 + + P+ CA + + G G+P T Sbjct: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEP-IGAPGT 4445 Score = 31.2 bits (69), Expect = 3.9 Identities = 29/104 (27%), Positives = 37/104 (35%), Gaps = 20/104 (19%) Query: 112 PPTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPAA 171 PPT + VS L+APP P PS PP P L +PA+ Sbjct: 4888 PPTQHSYTYNVSNLDVRQ-LSAPP--------------PEEPSP---PPSP--LAPSPAS 4927 Query: 172 PFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSG 215 P E P P P P + P ++ P + PP G Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEG 4971 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.127 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,428,004 Number of Sequences: 37866 Number of extensions: 2969692 Number of successful extensions: 29136 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 270 Number of HSP's successfully gapped in prelim test: 1713 Number of HSP's that attempted gapping in prelim test: 17063 Number of HSP's gapped (non-prelim): 9687 length of query: 789 length of database: 18,247,518 effective HSP length: 110 effective length of query: 679 effective length of database: 14,082,258 effective search space: 9561853182 effective search space used: 9561853182 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.