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Search of human proteins with 154146193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
(805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 1624 0.0
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 1624 0.0
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 131 2e-30
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 129 1e-29
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 129 1e-29
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 129 1e-29
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 123 6e-28
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 118 2e-26
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 111 2e-24
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 108 3e-23
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 106 7e-23
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 101 2e-21
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 100 4e-21
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 100 7e-21
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 98 3e-20
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 97 8e-20
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 96 2e-19
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 95 2e-19
gi|148746195 trichohyalin [Homo sapiens] 94 4e-19
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 91 6e-18
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 91 6e-18
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 89 2e-17
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 89 2e-17
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 89 2e-17
gi|125656165 THO complex 2 [Homo sapiens] 89 2e-17
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 89 2e-17
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 88 4e-17
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 87 5e-17
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 87 5e-17
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 87 6e-17
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 1624 bits (4206), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM 60
MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM
Sbjct: 1 MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM 60
Query: 61 MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV 120
MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV
Sbjct: 61 MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV 120
Query: 121 PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH 180
PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH
Sbjct: 121 PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH 180
Query: 181 PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL 240
PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL
Sbjct: 181 PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL 240
Query: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV 300
EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV
Sbjct: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV 300
Query: 301 EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD 360
EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD
Sbjct: 301 EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD 360
Query: 361 AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR 420
AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR
Sbjct: 361 AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR 420
Query: 421 QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN 480
QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN
Sbjct: 421 QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN 480
Query: 481 EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS
Sbjct: 481 EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
Query: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
Query: 601 SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA
Sbjct: 601 SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT 720
KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT
Sbjct: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT 720
Query: 721 FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR 780
FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR
Sbjct: 721 FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR 780
Query: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805
SRSVEKSQRSGKKASRKHKSKSRSR
Sbjct: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 1624 bits (4206), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM 60
MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM
Sbjct: 1 MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGM 60
Query: 61 MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV 120
MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV
Sbjct: 61 MPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIV 120
Query: 121 PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH 180
PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH
Sbjct: 121 PPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFH 180
Query: 181 PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL 240
PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL
Sbjct: 181 PPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL 240
Query: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV 300
EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV
Sbjct: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENV 300
Query: 301 EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD 360
EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD
Sbjct: 301 EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKD 360
Query: 361 AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR 420
AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR
Sbjct: 361 AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIR 420
Query: 421 QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN 480
QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN
Sbjct: 421 QKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVN 480
Query: 481 EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS
Sbjct: 481 EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
Query: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
Query: 601 SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA
Sbjct: 601 SIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT 720
KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT
Sbjct: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT 720
Query: 721 FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR 780
FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR
Sbjct: 721 FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR 780
Query: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805
SRSVEKSQRSGKKASRKHKSKSRSR
Sbjct: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 131 bits (330), Expect = 2e-30
Identities = 108/353 (30%), Positives = 173/353 (49%), Gaps = 42/353 (11%)
Query: 475 DGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS 534
DG VN +K ++E K + + RSRS S S S S +SR S + S S S
Sbjct: 161 DGTEVNGRK------IRLVEDKPGSRRRRSYSRSRSHSRSR-SRSRHSRKSRSRSGSSKS 213
Query: 535 SYSSSSGSSRTSSRSSSPKRKKRHSRSRS-------PTIKARRSRSRSYSRRIKIESNRA 587
S+S S SR+ SRS S R + SRSRS P+ + RSRS S + ++A
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT---NRASRSRSRDRRKIDD 644
KI+ N +++ + + R+ S + + +SRSRS++RR R S SR R + K
Sbjct: 274 EEKIQ-----NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK--- 325
Query: 645 QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKF 704
S + + +K R + RSRS KD++K K E R + + E+ K
Sbjct: 326 -----SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
Query: 705 SSQDD------RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG 758
S+ D + K+K +++R+ SRS S SV R ++ +S + + +++G++
Sbjct: 381 GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
Query: 759 RSSSESPGSSK-----EKKAKKPKHSRSRSVEKSQ-RSGKKASRKHKSKSRSR 805
RS S S SK E +++ S++RS KS+ RS ++ + +S+S SR
Sbjct: 441 RSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 105 bits (263), Expect = 1e-22
Identities = 91/321 (28%), Positives = 146/321 (45%), Gaps = 40/321 (12%)
Query: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNS 522
++S S +R G K R+ +++ S KKE + +SRS S S+G S S S
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRS--RSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 523 RTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKI 582
+ + ++ + S + +S S R + R + SR RS + ++
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
Query: 583 ESNRARVKIRDRRRSNRNSIERERRRNRSPSRE--RRRSRSRSRDRRTNRASRSRSRDRR 640
+R+R K R RS S +++R+ R SRE R RSRSRS+ R+ R
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS-----------R 378
Query: 641 KIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
K +R + +G+S K K E ++ + + SRS+ KERE + + +++ R E
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV-------SKEREHAKSESSQREGRGES 431
Query: 701 DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRS 760
+ ++Q+ R + SRS S S + +SR SK + SK S S S RS
Sbjct: 432 ENAGTNQETRSR---------SRSNSKSKPNLPSESRSRSKSA----SKTRSRSKSRSRS 478
Query: 761 SSESPGSSKEKKAKKPKHSRS 781
+S SP S+ + HSRS
Sbjct: 479 ASRSPSRSRSR-----SHSRS 494
Score = 90.1 bits (222), Expect = 7e-18
Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 19/288 (6%)
Query: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVT 452
SG S+ S S S + R R + + +KEK + +K + +
Sbjct: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
Query: 453 KEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
K ++ K QN+ +V K R+P+ S + + +E+ + R
Sbjct: 268 KSKDQAEEKIQNN----------DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
Query: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPT-IKARRS 571
S S + R S + S S S S S++ + KR + SRSRS + K+ RS
Sbjct: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
Query: 572 RSRSYSRRIKIESNRARVK---IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT 628
R R R K S++ + K R + RS S+ +ER +S S +R R S + T
Sbjct: 378 RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES-SQREGRGESENAGT 436
Query: 629 NRASRSRSRDRRKIDDQRGNLSGNSH-KHKGEAKEQERKKERSRSIDK 675
N+ +RSRSR K + NL S + K +K + R K RSRS +
Sbjct: 437 NQETRSRSRSNSK---SKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
Score = 68.6 bits (166), Expect = 2e-11
Identities = 71/342 (20%), Positives = 129/342 (37%), Gaps = 71/342 (20%)
Query: 237 REGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEED 296
R G + + + + R ++++S+ KEK + G + +SK ++E+ ++
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAG---KSRSKSKDQAEEKIQN 279
Query: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
+NV S +R S S EEEK +
Sbjct: 280 NDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV---------------------- 317
Query: 357 VAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELR 416
++ K L QS + + G S+D+R R ++ R
Sbjct: 318 -------SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR---KRSREESRSR 367
Query: 417 HRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
R R K E ++ ++ +++K+ T+R
Sbjct: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR-------------------------- 401
Query: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
+ R+P+ + S ++EH + E R G S + ++ +R+ S S++ S +
Sbjct: 402 ----SQSRSPSRSVS---KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454
Query: 537 SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
S SR+ S+S+S R + SRSRS + RSRSRS+SR
Sbjct: 455 PS---ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/268 (22%), Positives = 113/268 (42%), Gaps = 28/268 (10%)
Query: 363 RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQK 422
++ +++P+K+ ++S + + +G S + D+ E +D + + R
Sbjct: 244 KEKSRSPSKEKSRSRS------------HSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 423 QEAFWRKEKEQQLLHDKQMEEEKQQT-------ERVTKEMNEFIHKEQNSLSLLEAREAD 475
K K + ++++EEEK+ + E+ ++ + S S +R
Sbjct: 292 SR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 476 GDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSS 535
D +KR+ E+ S + + K ++ R R S + SS + + S S
Sbjct: 351 KDKRKGRKRSREESRS----RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406
Query: 536 YSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR---RIKIES-NRARVKI 591
S S R ++S S +R+ R + T + RSRSRS S+ + ES +R++
Sbjct: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
Query: 592 RDRRRSNRNSIERERRRNRSPSRERRRS 619
+ R RS S R +RS SR RS
Sbjct: 467 KTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 38.9 bits (89), Expect = 0.019
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
K ++ E +F S D + + + T I + + SR+ S ++ +
Sbjct: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196
Query: 754 SDSSGRSSSESPGSSKEKKAKKPKHSR--SRSVEKSQRSGKKASRKHKSKSRS 804
R S GSSK +K SR SRS KS+ + SR K KSRS
Sbjct: 197 RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS 249
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 129 bits (324), Expect = 1e-29
Identities = 103/345 (29%), Positives = 166/345 (48%), Gaps = 48/345 (13%)
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG--SS 513
N I K A+E + +V+ + + ++ +EP+ + K GRSRS S
Sbjct: 257 NNAIVKPPEMTPQAAAKELE-EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 315
Query: 514 SSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
S SS S+SR + S S S++ S + RS SP +K+ SR R R+SRS
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER------RKSRS 369
Query: 574 RSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
RS+SR D+R+ R I +E+ R + RE+ R R + R++ R +
Sbjct: 370 RSHSR--------------DKRKDTREKI-KEKERVKEKDREKEREREKEREKEKER-GK 413
Query: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE 693
++ RD+ + K + + KE++R++ER + +KDR DKE+E+EQDK KE
Sbjct: 414 NKDRDKER------------EKDREKDKEKDREREREKEHEKDR---DKEKEKEQDKEKE 458
Query: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
++K K+ D ++K + RT RS + S + R SR+ ++ + S+
Sbjct: 459 REKDRSKEI------DEKRKKDKKSRTPPRSYNAS-RRSRSSSRERRRRRSRSSSRSPRT 511
Query: 754 SDSSGRSSSESPG-SSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
S + R SS SP S+ KK KK + R E+ +R + RK
Sbjct: 512 SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Score = 73.9 bits (180), Expect = 5e-13
Identities = 71/292 (24%), Positives = 117/292 (40%), Gaps = 51/292 (17%)
Query: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
S + R R S ++ R +I++K+ KEK+++ +++ E EK++ K+
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDREKEREREKEREKEKERGKNKDR 417
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
++ K++ ++ + D E+++ + + K++ KEKE++
Sbjct: 418 DKEREKDRE-------KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 516 GSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRS 575
SRT S S S SSS R SRSSS S S TIK + SRS S
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS------RSPRTSKTIKRKSSRSPS 524
Query: 576 YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSR 635
+RN +++R + R ER R R+R T+ S
Sbjct: 525 --------------------PRSRNKKDKKREKERDHISER-----RERERSTSMRKSSN 559
Query: 636 SRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
RD ++ K+ KE+E KE S+ K+ KD R E
Sbjct: 560 DRDGKE----------KLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEE 601
Score = 37.7 bits (86), Expect = 0.043
Identities = 64/336 (19%), Positives = 118/336 (35%), Gaps = 62/336 (18%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
++RR S + R +S + D K +E +++ +REK+++ EKER
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER 405
Query: 256 -MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP 314
E++R + ++K+ +D E + K E E + E+ + K
Sbjct: 406 EKEKERGKNKDRDKEREKDRE---------KDKEKDREREREKEHEKDRDKEKEKEQDKE 456
Query: 315 VPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLA 374
+E+ E+ E+ K KD K ++ P +
Sbjct: 457 KEREKDRSKEIDEKRK----------------------------KD---KKSRTPPRSYN 485
Query: 375 QSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQ 434
S S S R R S S + ++ + + R +K
Sbjct: 486 ASRRSRS-----------SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK--- 531
Query: 435 LLHDKQMEEEKQQ-TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
DK+ E+E+ +ER +E + + K N E E + + EK+ +SV
Sbjct: 532 ---DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV- 587
Query: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSS 529
KE +K+ + +G+ N ST +
Sbjct: 588 --SKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKT 621
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 129 bits (324), Expect = 1e-29
Identities = 103/345 (29%), Positives = 166/345 (48%), Gaps = 48/345 (13%)
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG--SS 513
N I K A+E + +V+ + + ++ +EP+ + K GRSRS S
Sbjct: 141 NNAIVKPPEMTPQAAAKELE-EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 199
Query: 514 SSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
S SS S+SR + S S S++ S + RS SP +K+ SR R R+SRS
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER------RKSRS 253
Query: 574 RSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
RS+SR D+R+ R I +E+ R + RE+ R R + R++ R +
Sbjct: 254 RSHSR--------------DKRKDTREKI-KEKERVKEKDREKEREREKEREKEKER-GK 297
Query: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE 693
++ RD+ + K + + KE++R++ER + +KDR DKE+E+EQDK KE
Sbjct: 298 NKDRDKER------------EKDREKDKEKDREREREKEHEKDR---DKEKEKEQDKEKE 342
Query: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
++K K+ D ++K + RT RS + S + R SR+ ++ + S+
Sbjct: 343 REKDRSKEI------DEKRKKDKKSRTPPRSYNAS-RRSRSSSRERRRRRSRSSSRSPRT 395
Query: 754 SDSSGRSSSESPG-SSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
S + R SS SP S+ KK KK + R E+ +R + RK
Sbjct: 396 SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Score = 73.9 bits (180), Expect = 5e-13
Identities = 71/292 (24%), Positives = 117/292 (40%), Gaps = 51/292 (17%)
Query: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
S + R R S ++ R +I++K+ KEK+++ +++ E EK++ K+
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDREKEREREKEREKEKERGKNKDR 301
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
++ K++ ++ + D E+++ + + K++ KEKE++
Sbjct: 302 DKEREKDRE-------KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 516 GSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRS 575
SRT S S S SSS R SRSSS S S TIK + SRS S
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS------RSPRTSKTIKRKSSRSPS 408
Query: 576 YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSR 635
+RN +++R + R ER R R+R T+ S
Sbjct: 409 --------------------PRSRNKKDKKREKERDHISER-----RERERSTSMRKSSN 443
Query: 636 SRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
RD ++ K+ KE+E KE S+ K+ KD R E
Sbjct: 444 DRDGKE----------KLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEE 485
Score = 37.7 bits (86), Expect = 0.043
Identities = 64/336 (19%), Positives = 118/336 (35%), Gaps = 62/336 (18%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
++RR S + R +S + D K +E +++ +REK+++ EKER
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER 289
Query: 256 -MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP 314
E++R + ++K+ +D E + K E E + E+ + K
Sbjct: 290 EKEKERGKNKDRDKEREKDRE---------KDKEKDREREREKEHEKDRDKEKEKEQDKE 340
Query: 315 VPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLA 374
+E+ E+ E+ K KD K ++ P +
Sbjct: 341 KEREKDRSKEIDEKRK----------------------------KD---KKSRTPPRSYN 369
Query: 375 QSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQ 434
S S S R R S S + ++ + + R +K
Sbjct: 370 ASRRSRS-----------SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK--- 415
Query: 435 LLHDKQMEEEKQQ-TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
DK+ E+E+ +ER +E + + K N E E + + EK+ +SV
Sbjct: 416 ---DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV- 471
Query: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSS 529
KE +K+ + +G+ N ST +
Sbjct: 472 --SKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKT 505
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 129 bits (323), Expect = 1e-29
Identities = 90/263 (34%), Positives = 145/263 (55%), Gaps = 19/263 (7%)
Query: 543 SRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARV----KIRDRRRSN 598
SR+ RS SP+R R SRSRS + S S + R ++ E R R+ K R++ R
Sbjct: 260 SRSPRRSLSPRRSPRRSRSRSHHREGHGSSS--FDRELEREKERQRLEREAKEREKERRR 317
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH-KHK 657
SI+R R RS SRER RSRSRSRDR+ +R R R R++ +++RG + K +
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK---ENERGRRRDRDYDKER 374
Query: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRES 717
G +E+ER++ R RS ++ + + +E++ ++DK + + +++D K + R + +
Sbjct: 375 GNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK 434
Query: 718 ERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPG-SSKEKKAKKP 776
R+ SRS + + SR SK+ ++K K S S+ RS S S G + +K+KK
Sbjct: 435 HRSRSRSRNAGKR-----SRSRSKEKSSK-HKNESKEKSNKRSRSGSQGRTDSVEKSKKR 488
Query: 777 KHSRSRSVEKSQRSGKKASRKHK 799
+HS S+ EKS++ + R HK
Sbjct: 489 EHSPSK--EKSRKRSRSKERSHK 509
Score = 109 bits (272), Expect = 1e-23
Identities = 91/337 (27%), Positives = 147/337 (43%), Gaps = 42/337 (12%)
Query: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530
A E D V + R+P + L P++ + + R G SS R
Sbjct: 248 AEEIDRHVERRRSRSPRRS---LSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQ-- 302
Query: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590
R + ++++R SRS ++ RRSRSR R +R+R +
Sbjct: 303 -------------RLEREAKEREKERRRSRSIDRGLERRRSRSRERHR----SRSRSRDR 345
Query: 591 ---IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRG 647
RDR R ER RRR+R +ER R + R+R R+ RSR ++++++
Sbjct: 346 KGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG--EVEEKKH 403
Query: 648 NLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ 707
+ +H+ + ++ +++K+ SRS ++RK + + R R KR + + +EK K ++
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR-SRSRSKEKSSKHKNE 462
Query: 708 DDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS 767
KR SRSGS R DS + SKK SK+ S S + S
Sbjct: 463 SKEKSNKR------SRSGSQG----RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH 512
Query: 768 SKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
S + K + KH R RS Q S +K +HK+K +
Sbjct: 513 S-DSKDQSDKHDRRRSQSIEQESQEK---QHKNKDET 545
Score = 103 bits (257), Expect = 6e-22
Identities = 76/253 (30%), Positives = 123/253 (48%), Gaps = 20/253 (7%)
Query: 566 IKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRD 625
++ RRSRS S + R+R + R +S +RE R + R R ++ R ++
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314
Query: 626 RRTNRA-------SRSRSRDRRKIDDQRGNLSGNSH-KHKGEAKEQERKKERSRSIDKDR 677
RR +R+ RSRSR+R + + + G+ + + KE ER + R R DK+R
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKER 374
Query: 678 -KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHD- 735
+++KERER +++ KE++ R E + K +D +R R+ +R S K +H
Sbjct: 375 GNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD-------SKKEKKHSR 427
Query: 736 SRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKAS 795
SR +K ++ +++G S RS +S E K K K SRS S ++ K
Sbjct: 428 SRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKK 487
Query: 796 RKH---KSKSRSR 805
R+H K KSR R
Sbjct: 488 REHSPSKEKSRKR 500
Score = 80.9 bits (198), Expect = 4e-15
Identities = 72/269 (26%), Positives = 117/269 (43%), Gaps = 16/269 (5%)
Query: 400 RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFI 459
R GS S D + E + R R ++EA KE+E++ + ++ ++ ++E +
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREA---KEREKERRRSRSIDRGLERRRSRSRERHRSR 339
Query: 460 HKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS 519
+ ++ R+ + + NE+ R + + KE+E+ R RS S
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERS-RERSKEQRSRGEV 398
Query: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
+ S + SRS S +RK R SRSRS +RSRSRS +
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR-SRSRSRNA-GKRSRSRSKEKS 456
Query: 580 IKIESNRARVKIRDRRRSNR----NSIERERRRNRSPSRERRRSRSRSRDRRTNR----- 630
K N ++ K R RS +S+E+ ++R SPS+E+ R RSRS++R R
Sbjct: 457 SK-HKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDS 515
Query: 631 ASRSRSRDRRKIDDQRGNLSGNSHKHKGE 659
+S DRR+ HK+K E
Sbjct: 516 KDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 60.5 bits (145), Expect = 6e-09
Identities = 92/414 (22%), Positives = 158/414 (38%), Gaps = 92/414 (22%)
Query: 213 IALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATE 272
I +PV++ Q + R + +EG E+++R +E+ R R LS +
Sbjct: 221 IPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRH----VERRRSRSPRRSLSPR------ 270
Query: 273 DAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEY 332
R P+RS+ S E S R + + + E E EKE
Sbjct: 271 --------RSPRRSRSRSHHRE-------GHGSSSFDRELEREKERQRLEREAKEREKER 315
Query: 333 QMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYG 392
+ +D E +++ HR +++ ++ G
Sbjct: 316 RRSRS---------IDRGLERRRSRSRERHRSRSRSRDRK----------------GDRR 350
Query: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQ-EAFWRKEKEQQLLHDKQMEEEKQQTERV 451
D E E+ + D D ++ R R+K+ E + KEQ R
Sbjct: 351 DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQ----------------RS 394
Query: 452 TKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG 511
E+ E HKE + R D ++K++ + + S +E++ RSRS
Sbjct: 395 RGEVEEKKHKEDKD----DRRHRDDKRDSKKEKKHSRSRS----------RERKHRSRSR 440
Query: 512 SSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRS 571
S ++G S SR+ SS + S S+ SR+ S+ + +K R SP+ + R
Sbjct: 441 SRNAG-KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Query: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRD 625
RSRS R K RD S S + +RRR++S +E + + +++D
Sbjct: 500 RSRSKERSHK----------RDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 123 bits (309), Expect = 6e-28
Identities = 173/716 (24%), Positives = 279/716 (38%), Gaps = 80/716 (11%)
Query: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQ 167
P P T + P S S S + AP NR + P + +
Sbjct: 46 PTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
Query: 168 HGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAV 227
+ G H PG RR SS R R+ ++ +
Sbjct: 106 ASDVRCHQRRGTHSRGRTPG----------RRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
Query: 228 KRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSK 287
R P ++G + + +ER + Q LSKK + GG G
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP----GGSGIG------ 205
Query: 288 FDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSD---PEMTEEEKEYQMMLLTKMLLTE 344
+E S+ K ++P+ +P +E SD P + + K Y M++ +
Sbjct: 206 -------RSSELAVTPSTAKC-QTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKS- 256
Query: 345 ILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG 404
+ E+ K ++ +T++ + +QS + SG + S
Sbjct: 257 ----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR---------SGSQKRTHSRVR 303
Query: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQN 464
S S + R R R K Q H K + + +T R + N
Sbjct: 304 SHSWKRNHSRARSRTR-KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNW------- 355
Query: 465 SLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRT 524
S + + R + K+R ++S P+KE GRS+SGS + S SR+
Sbjct: 356 SRNPSKERSHSHSRSSSKERDHRGSSS---PRKE------SGRSQSGSPNKQRDHSRSRS 406
Query: 525 SSTSSTVSSS---------SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRS 575
+ + S S S S S +R SRS SP + + SRSRSP SRSRS
Sbjct: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
Query: 576 YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER--RRSRSRSRDRRTNRASR 633
++ +R+ K RD + S ER+ RR+RSPS+ER R+SRS S++R +R SR
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER-DHRRSR 525
Query: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK---KDKEREREQDK 690
S S++R++ + N + + + ++E+E ++ RS S ++DR++ KERER Q
Sbjct: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ-S 584
Query: 691 RKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
R ++R+ + ++ R R S E+ SRS + S + SR SK+S S
Sbjct: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
Query: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
D + S S +K HS S Q + S+ + S++
Sbjct: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
Score = 120 bits (300), Expect = 7e-27
Identities = 103/311 (33%), Positives = 149/311 (47%), Gaps = 30/311 (9%)
Query: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTS-SRSSSPKRK 555
K + R RS + S S S + S SS+ SSS + S+S SP ++
Sbjct: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
Query: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
+ HSRSRSP RSRSRS + +R+ K RD RS R+R R+RSP++
Sbjct: 399 RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
Query: 616 RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDK 675
R SRSRS ++ +R SRSRS + + Q G+ S + + +ER+ +SRS K
Sbjct: 459 RDHSRSRSPNKARDR-SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK 517
Query: 676 DRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHD 735
+R + R + KE+Q+R+ + +E +R+ SRS S +
Sbjct: 518 ER-----DHRRSRSPSKERQRRQSRS-----------PNKERDRSQSRSPSEE-----RE 556
Query: 736 SRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK-SQRSGKKA 794
RQ S +D ++ S S R +S SS+E+ HSRSRS K S S +A
Sbjct: 557 HRQSRSPSKERDRRRWR-SPSKERERRQSRSSSEER-----DHSRSRSPNKQSGYSRPRA 610
Query: 795 SRKHKSKSRSR 805
S K K+ SRSR
Sbjct: 611 SSKEKAHSRSR 621
Score = 72.8 bits (177), Expect = 1e-12
Identities = 93/361 (25%), Positives = 140/361 (38%), Gaps = 42/361 (11%)
Query: 482 KKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSS-S 540
K TPN + +P S+S S+S + ++R SS S S + S S
Sbjct: 36 KSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVS 95
Query: 541 GSSRTSSRSSSP-----KRKKRHSRSRSPTIKARRSRSRSYSR-----RIKIE------S 584
+RTS S + +R+ HSR R+P + RS RS SR RI+ +
Sbjct: 96 TDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
Query: 585 NRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD------ 638
+R R ++ S S R R NR S + R+ S+ R + RS +
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215
Query: 639 -----------RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
++ D S K G+ R+K S + R K +
Sbjct: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
Query: 688 QDKRKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVK-IIRHDSRQDSKKST 744
+ Q R + + SQ R R +R SR+ S + K I+ R +S
Sbjct: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
Query: 745 TKD-SKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
+K S+ S + GRS + S SKE + HSRS S E+ R G + RK +S+
Sbjct: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKE---RSHSHSRSSSKERDHR-GSSSPRKESGRSQ 391
Query: 804 S 804
S
Sbjct: 392 S 392
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 118 bits (295), Expect = 2e-26
Identities = 97/435 (22%), Positives = 184/435 (42%), Gaps = 43/435 (9%)
Query: 384 GLGGLGGYGSGDSED----ERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDK 439
GLG GD + + +R E T+ E R R R++++ RK + ++
Sbjct: 41 GLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHR---ER 97
Query: 440 QMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEH 499
Q + EK++ + +E + KE+N +E + + E +R + T ++
Sbjct: 98 QRDREKERERQTDRERDRQREKERN-----RQKERERETEREGERGRDRQTDGQRERERQ 152
Query: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS 559
++ EK+ ++ + N + + R R K + RHS
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREK------NRQERRERERQREKENKTEDRHS 206
Query: 560 RSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE----------RRRN 609
R R R R + E+ R R R+R R + ERE R
Sbjct: 207 E---------RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 610 RSPSRERRRSRSRSRDRRTNRASRS--RSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK 667
R RER R R R RDRR R R R RR D+ + + +E+ RK+
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 668 ERSRSIDKDR-KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL-KRKRESERTFSRSG 725
ER R +++R ++++ ER+RE+++ ++++++ E D + + Q R +R+ E ER R
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Query: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
R + +D + K+ ++ + D G+ +E + +K ++ + R R E
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK--QREREKDRESERGRERGRE 435
Query: 786 KSQRSGKKASRKHKS 800
+ ++ G++ R+ ++
Sbjct: 436 REKQKGRERDRERQT 450
Score = 101 bits (251), Expect = 3e-21
Identities = 83/377 (22%), Positives = 150/377 (39%), Gaps = 34/377 (9%)
Query: 430 EKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNET 489
++E+ +++ EK+QTER T E ++ RE D E++R +
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 490 TSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
K+ +++KE++ + G + +T R
Sbjct: 113 RDRQREKERNRQKERERETER----EGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Query: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
+R ++ R R + RR R R + K E + R R R E E R
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE---RGRERERERETETETERK 225
Query: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
R RER R R R+R +A R R+ +R D+ +E+ER +
Sbjct: 226 RQTDRERDRQRKTERERE-KQAERERASERETERDKE--------------RERERDR-- 268
Query: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLK-RKRESERTFSRSGSIS 728
D+DR ++ KERER+ D++ +Q+R E+D + + +R + R+RE ER R
Sbjct: 269 ----DRDRDRRQKERERQTDRK--RQRRTERDRETERKRERQRERERERERNRKRERERE 322
Query: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ 788
+ R R+ + + +K R + G ++A++ R R E+ +
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER---ERERERERDR 379
Query: 789 RSGKKASRKHKSKSRSR 805
+S ++ + + + R R
Sbjct: 380 QSAREREERERDRDRDR 396
Score = 100 bits (248), Expect = 7e-21
Identities = 95/421 (22%), Positives = 167/421 (39%), Gaps = 50/421 (11%)
Query: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWR---KEKEQQLLHDKQMEEEKQQTERV 451
+ E ER TD + R R R ++ R +E+++Q ++Q E E+++ +
Sbjct: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
Query: 452 TKEMNEFIHKEQNS------LSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQ 505
+E KE + RE + + E+KR + +K +E+EKQ
Sbjct: 188 RRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD--RQRKTEREREKQ 245
Query: 506 G-RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSP--------KRKK 556
R R+ + R + R R + +R++
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Query: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN------R 610
R R K R R R R + E+ R R K R+R+R + ++RER R R
Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
Query: 611 SPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS----GNSHKHKGEAKEQERK 666
RER R R R R R R R RDR + ++ G K +E++R+
Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 667 KERSRSIDKDR-KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
ER R ++R K+K +ER+RE+ ++ ++ ++ + + R +RSG
Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRT----------ARSG 475
Query: 726 SISVKIIRHDSRQDSK----KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
+++ D + ++ KS+ +D K S GR + S G ++ +P+
Sbjct: 476 -----VVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEK 530
Query: 782 R 782
R
Sbjct: 531 R 531
Score = 90.5 bits (223), Expect = 6e-18
Identities = 66/275 (24%), Positives = 136/275 (49%), Gaps = 30/275 (10%)
Query: 542 SSRTSSRSSSPKRK---KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
S R SP+R+ + H + + R + R RR K ++ R + R+RRR
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERE-RRREKRQTERETDRKRERRR-- 83
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRA---SRSRSRDRRKIDDQRGNLSGNSHK 655
E++R R R RER+R R + R+R+T+R R + R+R+K ++ G +
Sbjct: 84 ----EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Query: 656 HKGEAKEQER------KKERSRSIDKDR-------KKKDKEREREQDKRKEKQKREEKDF 702
+ ++ER +KER R D++R ++K++ERE+ + +R+E++++ EK+
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Query: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSS 762
K + R+RE ER + + + + + D +D ++ T ++ +K + + + +
Sbjct: 200 KTEDRHSERGRERERER---ETETETERKRQTDRERDRQRKTEREREKQAERERASERET 256
Query: 763 ESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
E +E++ + + R E+ +++ +K R+
Sbjct: 257 ER-DKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Score = 79.3 bits (194), Expect = 1e-14
Identities = 66/268 (24%), Positives = 118/268 (44%), Gaps = 46/268 (17%)
Query: 555 KKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSR 614
++R SP RR +++ + R R K R+RRR R + ER +R R
Sbjct: 28 RRRPGSQESPR---RRGLGQAHKDADGDDRERNRQKERERRREKRQT---ERETDRKRER 81
Query: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
R + R R RDR R R RDR K + ++++R+KER+R +
Sbjct: 82 RREKDRHRKRDRH-----RERQRDREK----------ERERQTDRERDRQREKERNRQKE 126
Query: 675 KDR-----------KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
++R ++ D +RERE+ + EK++ + D + Q +R R++E ER +R
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER-NRQKEREREKNR 185
Query: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK------KAKKPK 777
R RQ K++ T+D G + +E+ K + + +K +
Sbjct: 186 QER------RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE 239
Query: 778 HSRSRSVEKSQRSGKKASRKHKSKSRSR 805
R + E+ +R+ ++ + + K + R R
Sbjct: 240 REREKQAER-ERASERETERDKERERER 266
Score = 76.3 bits (186), Expect = 1e-13
Identities = 86/411 (20%), Positives = 162/411 (39%), Gaps = 55/411 (13%)
Query: 237 REGLEKMEREKQKKLEKER---MEQQRSQLSKKEKKATEDAEGG-----DGPRLPQRSKF 288
RE E+E++++ ++ER E++R++ ++E++ + E G DG R +R +
Sbjct: 95 RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR- 153
Query: 289 DSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348
D E+E + + R+ + E + E E E++ + T+ +E +
Sbjct: 154 --DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESS 408
E + R+ + +Q + + ER +
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTER---------------EREKQAERERASERET 256
Query: 409 DTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEK-QQTERVTKEMNEFIHKEQNSLS 467
+ D E R R R + +KE+E+Q +Q E+ ++TER + E + + +
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE--RERERERN 314
Query: 468 LLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
RE + + E++R ET E ++E K K + R + +G
Sbjct: 315 RKRERERERERERERQR---ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
R R S+ +R++R + R R R R + E +R
Sbjct: 372 E-------------RERERDRQSAREREER---------ERDRDRDRQKERERQTEKDRD 409
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR-ASRSRSR 637
+ +++R E ER R R RE+++ R R R+R+T+R A R R R
Sbjct: 410 GQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 67.4 bits (163), Expect = 5e-11
Identities = 49/207 (23%), Positives = 99/207 (47%), Gaps = 17/207 (8%)
Query: 602 IERERRRNRSPSRERRRSRSRS-RDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
++ RRR S RRR ++ +D + R+R ++R + ++R
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQT-----------E 72
Query: 661 KEQERKKERSRSIDKDRKK-KDKEREREQDKRKEKQKREEKDFKFSSQDDRLK-RKRESE 718
+E +RK+ER R D+ RK+ + +ER+R+++K +E+Q E+D + + +R K R+RE+E
Sbjct: 73 RETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE 132
Query: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
R R R RQ + K+ ++ + + ++ + +K ++ +
Sbjct: 133 REGERGRDRQTDGQRERERQ---RDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 779 SRSRSVEKSQRSGKKASRKHKSKSRSR 805
R R EK ++ + S + + + R R
Sbjct: 190 ERERQREKENKTEDRHSERGRERERER 216
Score = 56.6 bits (135), Expect = 9e-08
Identities = 83/427 (19%), Positives = 150/427 (35%), Gaps = 92/427 (21%)
Query: 196 QNRRERPSSFR-DRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK--LE 252
Q RER + +R R ++ Q DA K R RE + ER +QK+ E
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT-DRERQRQTERNRQKERERE 182
Query: 253 KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSP 312
K R E++ + ++++ TED G + + +++ E + + E K R
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 313 SPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQ 372
+ E + TE +KE + +D R + ++
Sbjct: 243 EKQAERERASERETERDKERER-----------------------ERDRDRDRDRRQKER 279
Query: 373 LAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKE 432
Q+ D + R +E D + E R R R+++ R K
Sbjct: 280 ERQT---------------------DRKRQRRTE-RDRETERKRERQRERERERERNRKR 317
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
++ ++ E +++TER ++ E K Q + RE + E +R
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMD----RERNRQTGREGRRQAER---- 369
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSP 552
E ++E + + R R R R
Sbjct: 370 -ERERERERDRQSARER------------------------------EERERDRDRDRQK 398
Query: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSP 612
+R+++ + R + + R R R ES R R + R+R + +RER+ +R
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDR----ESERGRERGREREKQKGRERDRERQTDRQA 454
Query: 613 SRERRRS 619
R+R+RS
Sbjct: 455 GRQRKRS 461
Score = 46.2 bits (108), Expect = 1e-04
Identities = 80/392 (20%), Positives = 138/392 (35%), Gaps = 76/392 (19%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
+N+ E S R R+R ++ + + ++R R+ K ERE++K+ E+ER
Sbjct: 198 ENKTEDRHSERGRERE------RERETETETERKRQTDRE-RDRQRKTEREREKQAERER 250
Query: 256 MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPV 315
++ ++ KE++ D + R +R + + + TE + + K R
Sbjct: 251 ASERETE-RDKERERERDRDRDRDRRQKERERQTDRKRQRRTER-DRETERKRERQRERE 308
Query: 316 PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQ 375
+ E + E E+E + E +D ++ + +Q
Sbjct: 309 RERERNRKRERERERERER-----------------ERQRETERDREKERERKRKRQTEM 351
Query: 376 SSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQL 435
D E R + E R R R +Q A R+E+E+
Sbjct: 352 -------------------DRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 436 LHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEP 495
D+Q E E+ QTE ++ DG EK+R +
Sbjct: 393 DRDRQKERER-QTE----------------------KDRDGQRETEKQREREKDRESERG 429
Query: 496 KKEHKEKEKQ-GRSRSGSSSSGSSSSNSRTSST-------SSTVSSSSYSSSSGSSRTSS 547
++ +E+EKQ GR R + + R ST + S S + +R
Sbjct: 430 RERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIR 489
Query: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
SSP+ K S A+ SR R RR
Sbjct: 490 WKSSPEDPKAASTRFPWGRPAKASRGRVAGRR 521
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 111 bits (278), Expect = 2e-24
Identities = 99/326 (30%), Positives = 153/326 (46%), Gaps = 39/326 (11%)
Query: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK---- 555
+ +++GRSRS S S N++ S + S S ++R SRS +P R+
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR 585
Query: 556 -----KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR 610
+R SRSR+PT RRSRSR+ +RR R+R + RRRS S R R R+R
Sbjct: 586 SRTPARRRSRSRTPT--RRRSRSRTPARR-----GRSRSRTPARRRSRTRSPVRRRSRSR 638
Query: 611 SPSRERRRSRSRSRDRRTNRASRS---RSRDRRKIDDQRGNLSGN---SHKHKGEAKEQE 664
SP+R RSRSR+ RR SR+ R R R + +R S + + + + ++
Sbjct: 639 SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
Query: 665 RKKERSRSI-----DKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
R + RSRS+ R + + R +RK K + ++ + S+ +K+ R S R
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR-SNSSPEMKKSRISSR 757
Query: 720 TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHS 779
RS S+S S + KS + SGS + S++P + +PK +
Sbjct: 758 ---RSRSLS-------SPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPK-A 806
Query: 780 RSRSVEKSQRSGKKASRKHKSKSRSR 805
+SR+ + RS K KSK+ SR
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSR 832
Score = 99.0 bits (245), Expect = 2e-20
Identities = 142/640 (22%), Positives = 242/640 (37%), Gaps = 86/640 (13%)
Query: 203 SSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME----- 257
SSF ++R+ A EPP+ ++ R + + R K +++K+KK R E
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSS--RSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 258 QQRSQLSKKEKKATEDAEGGDGPRLPQ-RSKFDSDEEEEDTENVEAASSGKVTRSPSPVP 316
++R + SKK+K +E R P +SK S +++ K +RS +P P
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR-----------KRSRSTTPAP 255
Query: 317 QEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQS 376
+ + + + + D R +++ A + +
Sbjct: 256 KSRRAHRSTSADSAS--------------------------SSDTSRSRSRSAAAK-THT 288
Query: 377 SALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLL 436
+ALA + G G GD+ S + E + E + +KE+
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
Query: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
E + S L + VN P S +
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN-----PPSEASPTRDR 403
Query: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSR------TSSRSS 550
K EK +S S SS S + SS+ S + + GS R TS S
Sbjct: 404 SPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS 463
Query: 551 SPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRS---NRNSIERERR 607
+ K+ S S +P+ + RSRS + ++R + S + R RS R+ +
Sbjct: 464 HGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWG 523
Query: 608 RNRSPSRERRRSRSR-------SRDRRTNRASRSRS----RDRRKIDDQRGNLSGNSHKH 656
R+RSP +RR RSR SR R T R RSRS R + RG +
Sbjct: 524 RSRSP---QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR 580
Query: 657 KGEAKEQERKKERSRSIDKDRK--------KKDKEREREQDKRKEKQKREEKDFKFSSQD 708
+G ++ + + RSRS R+ ++ + R R +R+ + + + + S+
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR-RSRSRS 639
Query: 709 DRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDS-SGRSSSESP-- 765
+ R RT +R G + R S+ + + S + + GRS S +P
Sbjct: 640 PARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699
Query: 766 GSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
G S+ + + S SR+ ++ RSG + RK+KS++ R
Sbjct: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR 739
Score = 98.2 bits (243), Expect = 3e-20
Identities = 102/361 (28%), Positives = 158/361 (43%), Gaps = 25/361 (6%)
Query: 461 KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEK----QGRSRSGSSSSG 516
K ++S A + + R+P+ L+ + +EK + R RSGSS S
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST 1797
Query: 517 S---SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
S S SR+ T S Y S S + + SSR+SS ++R RSR+P +RSRS
Sbjct: 1798 SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS---RRRRGRSRTPPTSRKRSRS 1854
Query: 574 RSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
R+ K +RA R RS I R R R+R+ RRRSRSR+ T R SR
Sbjct: 1855 RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT--SVTRRRSR 1912
Query: 634 SRSR--DRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
SR+ RR+ R + + R++ RSR+ R ++ + R +R
Sbjct: 1913 SRASPVSRRR---SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR-RRSRSRTPPVTRR 1968
Query: 692 KEKQK-----REEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTK 746
+ + + R + S R R R S T RS S + + R SR + + +
Sbjct: 1969 RSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRR 2028
Query: 747 DSKKHSGSDSSGRSSSESP-GSSKEKKAKKPKHSR-SRSVEKSQRSGKKASRKHKSKSRS 804
S+ + RS S SP + +++ P+ +R RS+ +S + ++ S S RS
Sbjct: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS 2088
Query: 805 R 805
R
Sbjct: 2089 R 2089
Score = 95.9 bits (237), Expect = 1e-19
Identities = 108/377 (28%), Positives = 157/377 (41%), Gaps = 37/377 (9%)
Query: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQG---RSRSGSSSSGSSS 519
++ LS +R V +K R S + E K + RSRSGSSS G
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP 1647
Query: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSS-SPKRKKR-HSRSRSPTIKARRSRSRSYS 577
S +SST SS + S ++R SRSS PK K R R RS +R S
Sbjct: 1648 S---PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704
Query: 578 RRIKIESN----RARVKIRDRRRSNRNSIE-----RERRRNRSPSRER-----RRSRSRS 623
RR + S+ R+R R RR + +S E R RR RS S R RR RS S
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 624 RDRRTNRASRSRSRDRRKIDDQRGNLSGNS-----HKHKGEAKEQERKKER------SRS 672
R + SRSRSR + +R + SG+S + + ++ + ++ R SRS
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 673 IDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKII 732
+ + R R R R+ + S + R R S T RS S + I
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 733 RHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP----KHSRSRSVEKSQ 788
R SR + + + S+ + S SP S + +++ P + SRSR+ +
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 789 RSGKKASRKHKSKSRSR 805
RS + + +SRSR
Sbjct: 1945 RSRSRTPPVTRRRSRSR 1961
Score = 90.9 bits (224), Expect = 4e-18
Identities = 155/675 (22%), Positives = 255/675 (37%), Gaps = 84/675 (12%)
Query: 166 YQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQID 225
Y G++F P + QP P PP P RE SS RSP K++ + D
Sbjct: 145 YVDGSSFDPQRRAREAK--QPAPE-PPKPYSLVRESSSS-----RSPTPKQKKKKKKK-D 195
Query: 226 AVKRRTLPAWIREGLEKMEREKQK-----KLEKERMEQQRSQLSKKEKKATEDAEGGDGP 280
+R + RE + +++K + K K R +S+ K+KK P
Sbjct: 196 RGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAP 255
Query: 281 --RLPQRSKFDSDEEEEDTENVEAASSGKVT-------RSPSPVPQEE------HSDPEM 325
R RS DT + S+ T RSPSP S+P
Sbjct: 256 KSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGT 315
Query: 326 TEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSA------- 378
T ++ TK + D++ KD K+ P+ +SS
Sbjct: 316 TSTQRPSSPETATKQPSSPY----EDKD-----KDKKEKSATRPSPSPERSSTGPEPPAP 366
Query: 379 ---LASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQL 435
LA G G + E + SE+S T D K +
Sbjct: 367 TPLLAERHG-GSPQPLATTPLSQEPVNPPSEASPTRDRS--------------PPKSPEK 411
Query: 436 LHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEK-KRTPNETTSVLE 494
L E + + TK ++ S A + ++ + + + + +
Sbjct: 412 LPQSSSSESSPPSPQPTK-VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD 470
Query: 495 PKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKR 554
H + GRSRS +++ S + + + S S S S++ RS SP+R
Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530
Query: 555 KKRHSRSRSPT----IKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR 610
+ RSRSP ++R ++ R SR + + +R R +R R R R+R
Sbjct: 531 R---GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSR 587
Query: 611 SPSRERRRSRSRSRDRRTNRA--SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
+P+R RRSRSR+ RR +R+ R R R + +R + + + + + ++ R+
Sbjct: 588 TPAR--RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
Query: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
RSRS R+ + + R + R + + + S+ +R R RT R S S
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP-ARRGRSRSRTPRRGRSRS 704
Query: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ 788
++ R+ S T + SGS SS R + + + P+ +SR S+
Sbjct: 705 RSLV----RRGRSHSRTPQRRGRSGS-SSERKNKSRTSQRRSRSNSSPEMKKSRI--SSR 757
Query: 789 RSGKKASRKHKSKSR 803
RS +S + K+KSR
Sbjct: 758 RSRSLSSPRSKAKSR 772
Score = 87.8 bits (216), Expect = 4e-17
Identities = 96/377 (25%), Positives = 158/377 (41%), Gaps = 36/377 (9%)
Query: 465 SLSLLEAREADGDVVNEKK-RTP--NETTSVLEPKKEHKEKEKQGRSRSGSS-------- 513
S S E E+D ++ K RTP + S P+ + K + RSRSGSS
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
Query: 514 -----SSGSSSSNSRTSSTSSTVSSSSYSSSSGSSR------TSSRSSSPKR--KKRHSR 560
SGS SS + + S S SS R +SS SSP+ K R +R
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669
Query: 561 SRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERR--- 617
S + +++SR+ RR S+ + R +R++ R+R+P R RR
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
Query: 618 -RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD 676
S + R++R RS S R K +RG + ++ + R+++ + +D
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 677 RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS---RSGSISVKIIR 733
R + R + + + + + + S R ++ES RT S R S + R
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSR 1849
Query: 734 HDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP-----KHSRSRSVEKSQ 788
SR + + K S+ + + RS S +P S+ + + + SRSR+ +
Sbjct: 1850 KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRR 1909
Query: 789 RSGKKASRKHKSKSRSR 805
RS +AS + +SRSR
Sbjct: 1910 RSRSRASPVSRRRSRSR 1926
Score = 86.3 bits (212), Expect = 1e-16
Identities = 152/683 (22%), Positives = 249/683 (36%), Gaps = 99/683 (14%)
Query: 182 PYWQPGPPGP--PAPPQNRRERPSS-FRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIRE 238
P+ +PG P+ P+ ++PSS + D+ + + P + P
Sbjct: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Query: 239 GLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGP-RLPQRSKFDSDEEEEDT 297
L + + L + Q+ E T D P +LPQ S +S
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVN-PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427
Query: 298 ENVEA-ASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
V ASS + P+P P EI T + +
Sbjct: 428 TKVSRHASSSPESPKPAPAPGSHR-----------------------EISSSPTSKNRSH 464
Query: 357 VAKDAHRKATKAPAKQLAQSSALA------SLTGLGGLGGYGSGDSEDERSDRGSES-SD 409
+ + P++++ +S + A S + G+ S R R ++
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 410 TDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLL 469
+ + R R R Q W + + Q + ++ R + + S S
Sbjct: 525 SRSPQRRGRSRSPQRPGWSRSRNTQ-------RRGRSRSARRGRSHSRSPATRGRSRSRT 577
Query: 470 EAREADGDVVNEKKRTP----NETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNS--- 522
AR + RTP + + + + + ++GRSRS + + S + S
Sbjct: 578 PARRG-----RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632
Query: 523 -RTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIK 581
R+ S S S S + + R SRS +P R+ R SRSR+P ++ RSRSR+ +RR +
Sbjct: 633 RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR-SRSRTPARRSGRSRSRTPARRGR 691
Query: 582 IESN---RARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT---------- 628
S R R + R R R+ +RR RS S R+++SR+ RR+
Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751
Query: 629 ----NRASRSRSRDRRKIDDQ---RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681
+R SRS S R K + R +LSG+S K +++ R+ S K + +
Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811
Query: 682 KEREREQDKRKEKQKRE---EKDFKFSSQDDRLKR---KRESERTFSRSGSISVKIIRHD 735
R R KQK + + SS ++K R+ T ++ SV R
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS 871
Query: 736 SRQDSK----KSTTKDSKKHSGSD------------SSGRSSSESPGSSKEKKAKKPKHS 779
+ S KS T SGS S RSSS P ++ HS
Sbjct: 872 CFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS 931
Query: 780 RSRSVEKSQRSGKKASRKHKSKS 802
S S S+ + + R+ +S S
Sbjct: 932 GSSSPSPSRVTSRTTPRRSRSVS 954
Score = 75.5 bits (184), Expect = 2e-13
Identities = 70/179 (39%), Positives = 90/179 (50%), Gaps = 31/179 (17%)
Query: 483 KRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGS 542
KR P+ T + E +E + E R SSS SSSS+S +SS+SS+ SSSS SSSS S
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 543 SRTSSRSSS----------------------PKRKKRHSRS-RSPTIKARRSRSRSYSRR 579
S +SS SSS P +R SRS R P R SRS SYS
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS-- 2694
Query: 580 IKIESNR--ARVKIRDRRRSN--RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRS 634
+E R + RD++ S+ R S +R +RSPS +RRR R R +R+SRS
Sbjct: 2695 -PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR-HRSSRS 2751
Score = 71.6 bits (174), Expect = 3e-12
Identities = 103/408 (25%), Positives = 152/408 (37%), Gaps = 74/408 (18%)
Query: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQ---GRSRSGSS-------------- 513
+R +N K TP S E + K + RSRSGSS
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556
Query: 514 ----SSGSSSSNSRT-------SSTSSTVSSSS----YSSSSGSS-------RTSSRSSS 551
SS S + +RT S +S V S S S SGSS R + R+ S
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 552 PKRKKRHSRSRSPTIKARRSRSRSYSR--------RIKIESNRAR-VKIRDRRRSNRNSI 602
++ +P RRSRS S S+ ES+ K R RR +R+S
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676
Query: 603 ERERRRNRSPSRER---------------RRSRSRSRDRRTNRASRSRSRDRRKIDDQRG 647
E + ++R+P R R RRSRS S T + R R +
Sbjct: 1677 E-PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
Query: 648 NLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ 707
S + + A K R K + +R R + +R++ + +D SSQ
Sbjct: 1736 AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795
Query: 708 DD--RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSES- 764
R +R R R R S R +RQ+S +++++ + S + + R S S
Sbjct: 1796 STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR 1855
Query: 765 ----PGSSKEKKAKKPKHSRSRS---VEKSQRSGKKASRKHKSKSRSR 805
P +A H RSRS + +RS + S + +SRSR
Sbjct: 1856 TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
Score = 65.5 bits (158), Expect = 2e-10
Identities = 117/512 (22%), Positives = 176/512 (34%), Gaps = 94/512 (18%)
Query: 185 QPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKME 244
+P P P A P+ R SS + R SP + P+ K RT R G
Sbjct: 1623 EPKAPAPRALPRRSRSGSSS-KGRGPSPEGSSSTESSPE-HPPKSRTA----RRGSRSSP 1676
Query: 245 REKQKKLEKERMEQQRS--QLSKKEKKATEDAEGGDGP-----------RLPQRSKFDSD 291
K K R RS +L++K + + P R P S +
Sbjct: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA 1736
Query: 292 EEEEDTENVEAASSGKVT------RSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEI 345
E+ + +ASS + RSPSP P+ + EK
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR------------- 1783
Query: 346 LLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGS 405
+ R + + Q S S GG G RS
Sbjct: 1784 -----------TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY----HSRSPARQ 1828
Query: 406 ESSDTDDEELRHRIR-----------QKQEAFWRKEKEQQ--LLHDKQMEE----EKQQT 448
ESS T R R R + A W++ + + H + ++++
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 449 ERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
T ++ + + S++ +R V ++R+ + T V + + + RS
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPV--SRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
Query: 509 RSGSSSSGSSSSNSRT---------------------SSTSSTVSSSSYSSSSGSSRTSS 547
RS + S SRT S TS S S +S +R S
Sbjct: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
Query: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR 607
RS + +R SRSR+P RRSRSR+ K +R+ + IR R RS R +R
Sbjct: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
Query: 608 R-NRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
RSP RRRS S S R+ A+ +R+
Sbjct: 2067 SLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Score = 60.8 bits (146), Expect = 5e-09
Identities = 82/392 (20%), Positives = 141/392 (35%), Gaps = 43/392 (10%)
Query: 442 EEEKQQTERVTK-----EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPK 496
EE Q VT+ E+NE ++ + + DG + ++R EP
Sbjct: 109 EETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPP 168
Query: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
K + + SRS + S + S S + S K++K
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
RSPT K++R S+ K + +R+ RR++R++ + + S +
Sbjct: 229 H----RSPTPKSKRK-----SKDKKRKRSRSTTPAPKSRRAHRST-----SADSASSSDT 274
Query: 617 RRSRSRSRDRRTNRA-----SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
RSRSRS +T+ S S + RR D + G + + + E K+ S
Sbjct: 275 SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
Query: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDR-----------------LKRK 714
DKD+ KK+K R + E +R +
Sbjct: 335 YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
Query: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK--KHSGSDSSGRSSSESPGSSKEKK 772
E+ T RS S + + S +S + + +K +H+ S + +PGS +E
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 773 AKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
+ +RS K +S + +SRS
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRS 486
Score = 60.1 bits (144), Expect = 8e-09
Identities = 64/221 (28%), Positives = 83/221 (37%), Gaps = 54/221 (24%)
Query: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS----------RTSSRSSSPK 553
K+ RS S SSSS SSSS+S +SS+SS+ S SS S S GSS R S + +PK
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSI----------- 602
R R PT R+ RS S S S+ + S+ +S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 603 ------------------------ERERRRNRSPSRERRRSRS---------RSRDRRTN 629
ER R R P R SRS R + +
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERS 670
R +S S +R QRG+ SHK + E + RS
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 55.8 bits (133), Expect = 2e-07
Identities = 77/304 (25%), Positives = 116/304 (38%), Gaps = 27/304 (8%)
Query: 514 SSGSSSSNSRTSSTSSTVSSSSYSSSS----GSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
SSG SSS + SS+ S SS RT SR S + P +R
Sbjct: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR 1437
Query: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTN 629
RSRS S S ++ S R S S + R+PSR R S +
Sbjct: 1438 RSRSGS-SPGLRDGSG------TPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
Query: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
+ R RSR + N + + ++ +K +R+ R + +E +
Sbjct: 1491 QTPRPRSRS--PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVK 1548
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGS---------ISVKIIRHDSRQDS 740
Q+R E D SS D + K R R SRSGS +S + R S +
Sbjct: 1549 PSASPQERSESD---SSPDSKAK-TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
Query: 741 KKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKS 800
K + SGSDSS + +P + ++++ S+ R S ++S +H
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAP-RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 801 KSRS 804
KSR+
Sbjct: 1664 KSRT 1667
Score = 53.5 bits (127), Expect = 8e-07
Identities = 63/283 (22%), Positives = 105/283 (37%), Gaps = 25/283 (8%)
Query: 487 NETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS---SNSRTSSTSSTVSSSSYSSSSGSS 543
N SV P H + + S S ++ + R SS+SS+ SSSS SSSS SS
Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550
Query: 544 RTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
+SS S S S S S + ++ A ++ + + ++
Sbjct: 2551 SSSSSSGS-------------------SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQ 663
R +P++ +RRS S S ++ +S S S + S +S +
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 664 ERKKERSRSIDKDRKKKDKEREREQDKRKE-KQKREEKDFKFSSQDDRLKRKRESERTFS 722
+ ++ KK R + RK R+ + +S + R + S R
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR--D 2709
Query: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
+ S S + R R DS+ + K ++ SS SP
Sbjct: 2710 QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 49.7 bits (117), Expect = 1e-05
Identities = 93/429 (21%), Positives = 161/429 (37%), Gaps = 43/429 (10%)
Query: 403 RGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE 462
RG S T R +++ R + + + ++ + + R ++ ++ K
Sbjct: 710 RGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKA 769
Query: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNS 522
++ LSL + +K +TP + + + K + RSRS SS S
Sbjct: 770 KSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP--PPKQKS 827
Query: 523 RTSSTSSTVSSSSY----------SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR--R 570
+T S S SSS + S S + + +S +P+R+ S P +K+R
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887
Query: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE-----RERRRNRSPSRERRRSRSRSRD 625
S S S +++S+ + R S + ++ R+R + S S R SR+
Sbjct: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947
Query: 626 RRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERE 685
RR+ S + + R + R + SG+S E ++ S SI K K +
Sbjct: 948 RRSRSVSPCSNVESRLL--PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPP 1005
Query: 686 RE--QDKRKEKQKREEKDFKFSSQDDRL------KRKRESERTFSRSGSISVKIIRHDSR 737
+ + + KD S L K ++ S+ +K
Sbjct: 1006 GPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK------- 1058
Query: 738 QDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS----VEKSQRSGKK 793
+ T+ D + + S +S SESP S + K PK RSRS E + RS +
Sbjct: 1059 --GQSQTSPDHRSDTSSPEVRQSHSESP-SLQSKSQTSPKGGRSRSSSPVTELASRSPIR 1115
Query: 794 ASRKHKSKS 802
R S S
Sbjct: 1116 QDRGEFSAS 1124
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 507 RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS-------SSSGSSRTSSRSSSPKRKKRHS 559
RSRS S + S SRT T+ S + S S+SGSS SRS++P + HS
Sbjct: 2041 RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
Query: 560 RSRSPTIKARRSRSRSYSR 578
SR+P + SR +SR
Sbjct: 2101 GSRTPPVALNSSRMSCFSR 2119
Score = 38.1 bits (87), Expect = 0.033
Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
Query: 712 KRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK 771
KRKR S + S S S S S S S++ S S S SS SSS SP +K
Sbjct: 2602 KRKRRSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Query: 772 KAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
PK + + +R + + S SR
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Score = 37.4 bits (85), Expect = 0.056
Identities = 50/226 (22%), Positives = 84/226 (37%), Gaps = 18/226 (7%)
Query: 483 KRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY-----S 537
+ TP + SV P + + S SGSSS + S + S S Y
Sbjct: 944 RTTPRRSRSV-SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002
Query: 538 SSSGSSRTSSRSSSPKRKKRHSRSRS--------PTIKARRSRSRSYSRRIKIESNRARV 589
+ G S + S+S P+ K + S +S +K+ SY ++ + +
Sbjct: 1003 TPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQL-KGQS 1061
Query: 590 KIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNL 649
+ RS+ +S E + + SPS + + S R + + + R I RG
Sbjct: 1062 QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121
Query: 650 SGNSHKHKGEAKEQERKKERSRS---IDKDRKKKDKEREREQDKRK 692
S + G + EQ R + S S +D + E + K K
Sbjct: 1122 SASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
Score = 34.7 bits (78), Expect = 0.36
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 8/77 (10%)
Query: 736 SRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSS---KEKKAKKPKHSRSRSVEKSQRSGK 792
S S S++ S S S SSG SSS+S GSS + + A K S + + +++ R G+
Sbjct: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
Query: 793 -----KASRKHKSKSRS 804
A RK +S S S
Sbjct: 2595 PPEPTPAKRKRRSSSSS 2611
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 108 bits (269), Expect = 3e-23
Identities = 107/373 (28%), Positives = 155/373 (41%), Gaps = 71/373 (19%)
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSP 552
L PK + K++EK+ S SSSS SS S+S + S S SS S S +++ S
Sbjct: 177 LIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS--------SSDSSDSESATEEKSK 228
Query: 553 KRKKRH---SRSRSPTIKARRSRSRSYSRRIKIESNRAR--------------------- 588
KRKK+H SR K R+ +S S + E+ A+
Sbjct: 229 KRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMR 288
Query: 589 ---VKIRDRRRSNRNSIERERRRNRSP------SRERRRSRSRS-------RDRRTNRAS 632
K ++ R NR ERER R +P S +RR +RS RR S
Sbjct: 289 KSPPKADEKERKNR---ERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS 345
Query: 633 RSRSRDRRKIDD------------QRGNLSGNSHKHKGEAKEQERKKERSRS--IDKDRK 678
RSRSRDR + + QR +S KG+ E KE RS K+RK
Sbjct: 346 RSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ 738
D E RK +++++ KD K +S++ ++R E + + K +
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 739 DSKKSTTKDSK------KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGK 792
+ KS +DSK K S S GR K+ +K RSRS EKS++
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 793 KASRKHKSKSRSR 805
K++ SKS+ +
Sbjct: 526 KSNEHDHSKSKEK 538
Score = 105 bits (261), Expect = 2e-22
Identities = 129/586 (22%), Positives = 230/586 (39%), Gaps = 57/586 (9%)
Query: 241 EKMEREKQKKLEKERMEQQRSQLSK----------KEKKATEDAEGGDGPRLPQRSKFDS 290
E + + K KK EK+R + S S + + D+E + +R K
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 291 DEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVT 350
+ + + K + S + + P+ T +E + + L+ +
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD 295
Query: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDT 410
++E ++ R+ P Q A +T SG R R +
Sbjct: 296 EKERKNRERERERECNP-PNSQPASYQRRLLVTR--------SGRKIKGRGPRRYRTPSR 346
Query: 411 DDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLE 470
R R R + WR+E Q ++ ++ + E+NE +++ + + E
Sbjct: 347 SRSRDRFR-RSETPPHWRQE--MQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKE 403
Query: 471 AREADGDVVNEKKRTPNETTS-VLEPKKEHKEK------EKQGRSRSGSSSSGSSSSNSR 523
+ D V+E NE V + K KE+ EK + ++ S S S+
Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSK 463
Query: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKR---KKRHSRSRSPTIKARRSRSRSYSRRI 580
+ S + S + + R SRS K++ +S S RSRS+ S+++
Sbjct: 464 SKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQL 523
Query: 581 KIESNR---ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSR 637
+ +SN ++ K +DRR +R S E + + + R R RSRSRDR SR+ R
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQSR-SRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDR 582
Query: 638 DRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK-----KDKEREREQDKRK 692
DR + + ++ +G ++ +ER+ RS KDR++ + ERE Q + K
Sbjct: 583 DRSRSKEYH-RYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641
Query: 693 EKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS 752
+K + +E S R + +R +S+S H+S +S++ K + S
Sbjct: 642 DKYRNQE-----SKSSHRKENSESEKRMYSKSRD-------HNSSNNSREK--KADRDQS 687
Query: 753 GSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKH 798
+SS ++ S K K+ + RS SVEK + K H
Sbjct: 688 PFSKIKQSSQDNELKSSMLKNKEDEKIRS-SVEKENQKSKGQENDH 732
Score = 98.2 bits (243), Expect = 3e-20
Identities = 111/467 (23%), Positives = 188/467 (40%), Gaps = 65/467 (13%)
Query: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVT 452
S S+ + S SSD+ D E + K+ +K ++ H K+ ++ K+ + +
Sbjct: 199 SSSSDSDSSSDSQSSSDSSDSESATEEKSKKRK--KKHRKNSRKHKKEKKKRKKSKKSAS 256
Query: 453 KEMNEFIHKEQNSLSLLEAREADGDVVNE--KKRTPNETTSVLEPKKEHKEKEKQGRSRS 510
E +E + E S + E N +++P PK + KE++ + R R
Sbjct: 257 SE-SEAENLEAQPQSTVRPEEIPPIPENRFLMRKSP--------PKADEKERKNRERERE 307
Query: 511 GSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS-RTSSRSSSPKRKKRHSRS---RSPTI 566
+ +S S T S RT SRS S R +R R
Sbjct: 308 RECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQ 367
Query: 567 KARRSRSRSYSRRIK---------IESNRARVKIRDRRRSNRNSIERERRRNRSPSRERR 617
+A+R R S R IK E+ R+ V++++R+ ++ ++ R ++ +
Sbjct: 368 RAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVK 427
Query: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQ-------ERKKERS 670
+S S++R R S + + K+ + + S + K K ++KE+ E K+ RS
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRS 487
Query: 671 RSIDKDR------------KKKDKEREREQDKRKE-KQKREEKDFKFSSQDDRLKRKRES 717
RS +D K KD+ER R ++K K+ + K E D S + DR + R
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 718 E----------------RTFSRSGSISVKIIRHDSRQDSKKS--TTKDSKKHSGSDSSGR 759
E R+ SR S V+ HD + K ++ + S R
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSR 607
Query: 760 SSSESPGSSKEK-KAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
PG S+ K + ++ + SRS E+SQ K R +SKS R
Sbjct: 608 ERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHR 654
Score = 90.5 bits (223), Expect = 6e-18
Identities = 126/594 (21%), Positives = 228/594 (38%), Gaps = 106/594 (17%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDA-----VKRRTLPAWIREGLEKMEREKQKK 250
+N R+ + R++S + + E ++A V+ +P I E M + K
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP-IPENRFLMRKSPPKA 294
Query: 251 LEKERMEQQR----------SQLSKKEKKATEDAEG----GDGPR---LPQRSKFDSDEE 293
EKER ++R SQ + +++ G G GPR P RS+
Sbjct: 295 DEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFR 354
Query: 294 EEDT-----ENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348
+T + ++ A +V+ + ++ E+ E ++ + K
Sbjct: 355 RSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK--------- 405
Query: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESS 408
+TD HR +++P ++ + + +S++ R SE
Sbjct: 406 ITD----------HRNVSESPNRKNEKEKKVKD----------HKSNSKERDIRRNSEKD 445
Query: 409 DTDDEELRHRIRQKQEAFWR---KEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNS 465
D +++ R + K + + K KE+ H++ EEK+ R +E + KE+
Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN--EEKRMRSRSKGRDHENV-KEKEK 502
Query: 466 LSLLEAREADGDVVNEK-KRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRT 524
S + ++ + EK K+ +++ K + K++ Q RSR + G S NSRT
Sbjct: 503 QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRT 562
Query: 525 SSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIES 584
S SR SR R + H R RS + + R R + Y R
Sbjct: 563 RERS-------------RSRDRSRR---VRSRTHDRDRSRSKEYHRYREQEYRR------ 600
Query: 585 NRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDD 644
R R + R+RR S ++RRR R SR R S+SR++ R S+S R++ +
Sbjct: 601 -RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 645 QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKF 704
+ S H +E+K +R +S K+ ++ E + K K
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNK---------- 709
Query: 705 SSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG 758
+D++++ E E S+ +D + K +S + D SG
Sbjct: 710 --EDEKIRSSVEKENQKSKGQ-------ENDHVHEKNKKFDHESSPGTDEDKSG 754
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 713 RKRESERTFSRSGSIS-VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK 771
R+ E+++T + S + V+I+ K ++ K+H S SS SSS+S SS +
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ 211
Query: 772 KAKKPKHSRSRSVEKSQRSGK---KASRKHKSKSRSR 805
+ S S + EKS++ K K SRKHK + + R
Sbjct: 212 SSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKR 248
Score = 39.3 bits (90), Expect = 0.015
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 13/123 (10%)
Query: 682 KEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSK 741
+E E ++ K E + + K K+E ++ S S S DS DS+
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ 211
Query: 742 KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSK 801
S SDS S SES K KK KK SR +K ++ KK+ + S+
Sbjct: 212 ----------SSSDS---SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSE 258
Query: 802 SRS 804
S +
Sbjct: 259 SEA 261
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 106 bits (265), Expect = 7e-23
Identities = 111/438 (25%), Positives = 182/438 (41%), Gaps = 51/438 (11%)
Query: 393 SGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVT 452
S D D RS R ++ D D E R R K++ + + + H + EE +TE
Sbjct: 492 SRDPRDSRSTR--DAHDYRDREGRDTHR-KEDTYPEESRSYGRNH---LREESSRTEIRN 545
Query: 453 KEMNEFIHKEQNS-----------LSLLEAREADGDVVNEKKRTPN-----ETTSVLEPK 496
+ NE + +N L +R + G ++ N ET S +
Sbjct: 546 ESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPER 605
Query: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
+ E++ + ++R S + R + SS R R+ +R +
Sbjct: 606 DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPI-------RHQGRNDELERDE 658
Query: 557 RHSRSRSPTIKARR---SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
R R + RR +R R R E R R + RDR R +ERER R R
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERE 718
Query: 614 RERRRSRSRSRDRRTNRA-SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRS 672
RE+ R R R RDR +R R R RDR K + +R + + +E+ER++ER R+
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREK-EREREREERERERERERERERERERERERA 777
Query: 673 IDKDRKKKDKEREREQD-KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKI 731
+++DKERER++D + K+K + + ++ + ++DR R ER S K
Sbjct: 778 -----RERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK-------SKKR 825
Query: 732 IRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS----VEKS 787
R++ ++S + + SD+ ++ + +P+ SRS S E
Sbjct: 826 YRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 788 QRSGKKASRKHKSKSRSR 805
Q K+ RK + K SR
Sbjct: 886 QGRWKEEDRKPERKESSR 903
Score = 77.8 bits (190), Expect = 4e-14
Identities = 121/600 (20%), Positives = 220/600 (36%), Gaps = 60/600 (10%)
Query: 242 KMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPR--LPQRSKFDSDEEEEDTEN 299
K +REK + E+E + Q S ++ + D R +R DS + + E
Sbjct: 423 KRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREM 482
Query: 300 VEAASSGKVTRSP----SPVPQEEHSDPE----------MTEEEKEY-QMMLLTKMLLTE 344
+ + K +R P S ++ D E EE + Y + L + TE
Sbjct: 483 RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542
Query: 345 ILLDVTDEEIYYVAKD----AHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDER 400
I + +E + D + + + P K ++ S + + Y DS + R
Sbjct: 543 IRNESRNESRSEIRNDRMGRSRGRVPELPEKG-SRGSRGSQIDSHSSNSNYH--DSWETR 599
Query: 401 S-----DRGSESSDTDDE-----ELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTER 450
S DR E + D E RH R +++ R ++ + + +E ++ ER
Sbjct: 600 SSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDER 659
Query: 451 VTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRS 510
+ + + ++ + RE + D E++R E E ++E + + + R R
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERE-RERDREREKERELERERARERERE 718
Query: 511 GSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARR 570
R R +R++ R R + R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
R + R+ E + K RD RR R I +R N + R+S+ R R+ +
Sbjct: 779 ERDKERERQRDWED---KDKGRDDRREKREEIREDR--NPRDGHDERKSKKRYRNEGSPS 833
Query: 631 ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID-----KDRKKKDKERE 685
+S R R D SG+ K Q + + SRS+ +DR+ + KE +
Sbjct: 834 PRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED 893
Query: 686 REQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRH---------DS 736
R+ ++++ ++ EE++ K + + ++RE S + II H D
Sbjct: 894 RKPERKESSRRYEEQELK--EKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 737 RQDSKKSTTKDSK---KHSGSDSSGRSSSESPGSSKEKKAKKPKH-SRSRSVEKSQRSGK 792
D K K K K D G +S++ + PK + +S+EK ++ K
Sbjct: 952 AHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSK 1011
Score = 72.4 bits (176), Expect = 2e-12
Identities = 72/321 (22%), Positives = 136/321 (42%), Gaps = 29/321 (9%)
Query: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
+ E +R D + E R R R+K+ R+E+E++ +++ E E+++ +E
Sbjct: 720 EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARE 779
Query: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS 514
+ KE+ E ++ D EK+ E + P+ H E++ + R R+ S
Sbjct: 780 RD----KERERQRDWEDKDKGRDDRREKREEIREDRN---PRDGHDERKSKKRYRNEGSP 832
Query: 515 SGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-------- 566
S S R + + + +S + R S+ P+ SRS SP+
Sbjct: 833 SPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE----SRSLSPSHLTEDRQGR 888
Query: 567 ---KARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS----PSRERRRS 619
+ R+ + SRR + + + +V D++R +E R R + E R +
Sbjct: 889 WKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRET 948
Query: 620 RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK-ERSRSIDKDRK 678
R+ D +A + ++K +D G GN + + KK ++ +SI+K RK
Sbjct: 949 SDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRK 1008
Query: 679 KK--DKEREREQDKRKEKQKR 697
K D + E+ ++ K+KR
Sbjct: 1009 KSKGDSDISDEEAAQQSKKKR 1029
Score = 72.0 bits (175), Expect = 2e-12
Identities = 138/708 (19%), Positives = 276/708 (38%), Gaps = 135/708 (19%)
Query: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLE 252
A + R R+R R ++ + D K R RE + ERE++++ E
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771
Query: 253 KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSP 312
+ER + ++ ++ ED + G R +R + D D + E S +
Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHD-ERKSKKRYRNEG 830
Query: 313 SPVPQE------EHS---DPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
SP P++ EHS D + ++K + LL++++ + ++ + + +
Sbjct: 831 SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWK 890
Query: 364 KATKAPA---------------------KQLAQSSALAS--LTGLGGLGGYGSGDSE--- 397
+ + P KQ Q+ L S + +G + S D E
Sbjct: 891 EEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSD 950
Query: 398 -----------------------DERSDRGS-ESSDTDDEELRHRIRQKQEAFWRKEKEQ 433
D +RG+ E++ D + + QK+++ +K K+
Sbjct: 951 RAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKS 1010
Query: 434 QLLHDKQMEEEKQQTER----------VTKEMNEFIHKEQNSLSLLEARE-------ADG 476
+ D EE QQ+++ +E+ E + + L + +E +D
Sbjct: 1011 KGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDE 1070
Query: 477 DV-----VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTV 531
DV V E + T TT P + ++++ ++ + T++ +++
Sbjct: 1071 DVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSF 1130
Query: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR-SRSYSRRIKIESNRARVK 590
S+S+ + S+ ++ T++ +++ + H K R+R + + + IE + R
Sbjct: 1131 STSAITISTSATPTNTTNNTFANEDSHR-------KCHRTRVEKVETPHVTIEDAQHRKP 1183
Query: 591 IRDRRRS----NRNSIERERRRNRSPSRE------------RRRSRSRSRDRRTNRASRS 634
+ +R S NR++ R RSPS + +R S SRDR ++
Sbjct: 1184 MDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEI 1243
Query: 635 RSRDRRKIDD-QRGNLS---------GNSHKHKGEAKEQERK--------KERSRSIDKD 676
+ +ID +RG S SH + + E +R+ R R ++D
Sbjct: 1244 TGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERD 1303
Query: 677 RKKKDKEREREQ--DKRKEKQKREEKDFKFSSQDDRLK---------RKRESERTFSRSG 725
R + D+ERERE+ +++E + +KD+ + DRL+ ++R+ +R R
Sbjct: 1304 RYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLI 1363
Query: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKA 773
S SV+ R R + +S+ +S K + G + +S++ A
Sbjct: 1364 SDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLA 1411
Score = 67.8 bits (164), Expect = 4e-11
Identities = 89/404 (22%), Positives = 159/404 (39%), Gaps = 42/404 (10%)
Query: 416 RHRIRQKQEAFWRKEKEQQLLHDK-----QMEEEKQQTERVTKEMNEFIHKEQNSLSLLE 470
+ + +++E +KE +++ K + + + +R + + K+ S +
Sbjct: 182 QENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVS 241
Query: 471 AREAD---GDVVNEKK----RTPNETTSVLEP---KKEHKEKEK-----QGRSRSGSSSS 515
+ D N+ K RTP+ + E K++KEK K + ++R G
Sbjct: 242 SPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRG 301
Query: 516 GS-SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSR 574
+ ST + + S S SS S S +RHS P+ + +R+ S
Sbjct: 302 RDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHS----PSPRRKRTPSP 357
Query: 575 SYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRS 634
SY R + R+ S+ +R +SP R R R + R R S+S
Sbjct: 358 SYQRTLTPPLRRSASPYPSHSLSS-------PQRKQSPPRHRSPMREKGRHDH-ERTSQS 409
Query: 635 RSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD-KEREREQDKRKE 693
R + +D RG + K E +E E+ + SR DR+ +D ++R +D R
Sbjct: 410 HDRRHERREDTRG--KRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSR-QDSKKSTTKDSKKHS 752
++ R+ +D + S + R + R S S HD R ++ + + K+
Sbjct: 468 RELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR---DAHDYRDREGRDTHRKEDTYPE 524
Query: 753 GSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASR 796
S S GR+ S E + + SRS ++ R G+ R
Sbjct: 525 ESRSYGRNHLREESSRTE--IRNESRNESRSEIRNDRMGRSRGR 566
Score = 65.5 bits (158), Expect = 2e-10
Identities = 90/327 (27%), Positives = 131/327 (40%), Gaps = 76/327 (23%)
Query: 481 EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
EK TP+ T +E + K +++ S GS+ S S ++ R S S+ + S S
Sbjct: 1166 EKVETPHVT---IEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQS 1222
Query: 541 GSSR-----------------TSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIE 583
G R T R S + KR SRS + + SRS S SRR E
Sbjct: 1223 GRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS-SRRSSPE 1281
Query: 584 SNRA------------RVKIRDRRRSNRNSIERERRRNRSPSRE----------RRRSRS 621
S+R R++ RDR +R ERER R + RE R R R
Sbjct: 1282 SDRQVHSRSGSFDSRDRLQERDRYEHDR---ERERERRDTRQREWDRDADKDWPRNRDRD 1338
Query: 622 RSRDRRTNRASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKK 680
R R+R R R RD RR +D +R L +S ER R D+DR +
Sbjct: 1339 RLRER-----ERERERDKRRDLDRERERLISDS-------------VERDRDRDRDRTFE 1380
Query: 681 DKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
+ E + + + E+D + +S+D K ER GS+ +++
Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDK---ERMDKDLGSV-------QGFEET 1430
Query: 741 KKSTTKDSKKHSGSDSSGRSSSESPGS 767
KS +S + +G D S + S GS
Sbjct: 1431 NKSERTESLE-AGDDESKLDDAHSLGS 1456
Score = 56.2 bits (134), Expect = 1e-07
Identities = 125/649 (19%), Positives = 230/649 (35%), Gaps = 115/649 (17%)
Query: 236 IREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEE 295
+RE ++ ++ + +K E+ S + +KE E D +R+ +E E
Sbjct: 85 LRERMKNKRQDVDTEPQKRNTEESSSPV-RKESSRGRHREKEDIKITKERTPESEEENVE 143
Query: 296 DTENVEAASSGKVT----RSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTD 351
N + + +G + S + + E+ + E+E ++ E+ +V
Sbjct: 144 WETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVR 203
Query: 352 EEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTD 411
++ + RK++K+P ++ + S+ AS +D ++ + SS
Sbjct: 204 SKLS--PSPSLRKSSKSPKRKSSPKSSSAS--------------KKDRKTS--AVSSPLL 245
Query: 412 DEELRHRIRQKQEAFWRKEKE-----QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSL 466
D++ + Q ++ R + + K+ +E+ + +R+ ++ +
Sbjct: 246 DQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDG-------- 297
Query: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
+ R D + EK+ P T+ P +H R S SS SGSS S
Sbjct: 298 ---KDRGRDFERQREKRDKPRSTS----PAGQH-HSPISSRHHSSSSQSGSSIQRHSPSP 349
Query: 527 TSSTVSSSSYSSS-------SGSSRTSSRSSSPKRKKRHSRSRSPTIKARR--------S 571
S SY + S S S SSP+RK+ R RSP + R S
Sbjct: 350 RRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQS 409
Query: 572 RSRSYSRRIKIESNRARVK-----------------------------------IRDRRR 596
R + RR R R K RDRR
Sbjct: 410 HDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRE 469
Query: 597 SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD----RRKID--DQRGNLS 650
+ R+ R R SR+ + SR R T A R R+ RK D +
Sbjct: 470 LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSY 529
Query: 651 GNSHKHKGEAKEQERKKERSRS---IDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS- 706
G +H + ++ + R + R+ S I DR + + R E ++ + R + SS
Sbjct: 530 GRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSN 589
Query: 707 ---------QDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS 757
+ +R R ER +R + R +D + + +D + S
Sbjct: 590 SNYHDSWETRSSYPERDRYPERD-NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQ 648
Query: 758 GRSSS-ESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GR+ E +E++ + R + R ++ + + + R R
Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERER 697
Score = 44.3 bits (103), Expect = 5e-04
Identities = 85/414 (20%), Positives = 162/414 (39%), Gaps = 49/414 (11%)
Query: 196 QNRRERPSS-FRDRQRSP-IALPVKQEPPQIDAVK-RRTLPAWIREGLEKMEREKQKKLE 252
+ R +RPSS R + R+ + ++E ++D V RR A R+ + +RE++++ E
Sbjct: 635 RERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERE 694
Query: 253 KER---------MEQQRSQLSKKEKKATEDAE---GGDGPRLPQRSKFDSDEEEEDTENV 300
+ER +E++R++ ++E++ D E D R +R + E+E + E
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 301 EAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDE-EIYYVAK 359
E + R + E ++E+E Q K + + +E +
Sbjct: 755 ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPR 814
Query: 360 DAH--RKATKAPAKQLAQS---SALASLTGLGGLGGYGSGDSEDERSD------RGSESS 408
D H RK+ K + + S S Y SGD ++E+ R ES
Sbjct: 815 DGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESR 874
Query: 409 DTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL 468
L + ++ W++E + ++ E ++ E+ KE + K++ +
Sbjct: 875 SLSPSHL----TEDRQGRWKEEDRK----PERKESSRRYEEQELKEKVSSVDKQREQTEI 926
Query: 469 LE-AREADGDVVNEKKRTPNETTSVLEPKKEHKEK-EKQGRSRSGSSSSGSSSSNSRTSS 526
LE +R D++ + ET+ + + K K +K+ + G N T+S
Sbjct: 927 LESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTS 986
Query: 527 TSSTVSS-----------SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
V S S G S S ++ + KK+ R+P I +
Sbjct: 987 EDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRG-PRTPPITTK 1039
Score = 42.7 bits (99), Expect = 0.001
Identities = 46/238 (19%), Positives = 97/238 (40%), Gaps = 20/238 (8%)
Query: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
R + YS + R +R+R ++ R ++ E ++R S S R+ +
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTE-------PQKRNTEESSSPVRKESSR 118
Query: 632 SRSRSRDRRKIDDQRGNLSGNSH----KHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
R R ++ KI +R S + ++ ++ + + + + K++ +RE
Sbjct: 119 GRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELM 178
Query: 688 QDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
+ +++ +KREE K + ++ K + +S + R+ S KS++
Sbjct: 179 KLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSS-------KSPKRKSSPKSSSAS 231
Query: 748 SK-KHSGSDSSGRSSSESPGSSKEKKAKKPK-HSRSRSVEKSQRSGKKASRKHKSKSR 803
K + + + SS + + + K K P+ S + + GKK K+K K R
Sbjct: 232 KKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDR 289
Score = 33.1 bits (74), Expect = 1.1
Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 9/124 (7%)
Query: 687 EQDKRKEKQKREEK-DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTT 745
E RK + R EK + + +D RK ++ RS S+ +S +
Sbjct: 1154 EDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQK---RSSSLGSNRSNRSHTSGRLRSPS 1210
Query: 746 KDSKKHSGSDSSGRSSSESPGSSKEKKAKK-----PKHSRSRSVEKSQRSGKKASRKHKS 800
DS SG D SGR GS +K K + SR +++ + S +S + S
Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDS 1270
Query: 801 KSRS 804
+S S
Sbjct: 1271 RSHS 1274
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 101 bits (252), Expect = 2e-21
Identities = 128/489 (26%), Positives = 207/489 (42%), Gaps = 87/489 (17%)
Query: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
E + KME ++ + M+++ Q+ + E++ E EG ++ QR +EE E+T
Sbjct: 276 EQINKMEARPRR----QSMKEKEHQVVRNEEQKAEQEEG----KVAQR-----EEELEET 322
Query: 298 EN----VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKM------------- 340
N VE +G+ + HSD E +EE+E + + KM
Sbjct: 323 GNQHNDVEIEEAGEEEEKEIAIV---HSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQ 379
Query: 341 -LLTEILLDVTD--EEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSE 397
E ++DV + E + +V D T + + S AS + D E
Sbjct: 380 DSQPEEVMDVLEMVENVKHVIADQEVMETNR-VESVEPSENEASKELEPEMEFEIEPDKE 438
Query: 398 DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNE 457
+ G E+ D E ++++E+ + E Q Q + + Q + +
Sbjct: 439 CKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQP 498
Query: 458 FIHKEQNSLSLLE----AREADGDVVNEKKRTPNETTSVLE----------PKKEHKEKE 503
E SL++L+ + G ++ E+K P E+ + E P+ + K K
Sbjct: 499 PSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKT 558
Query: 504 K---QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG--SSRTSSRSSSPKRKKRH 558
+ +GR+R+ +S S S SS+S +SS+SST SSS SSSSG SSR+SS SSS
Sbjct: 559 RSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSS 618
Query: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
S S T + SRSRS R +R R +R S++R+RR R +
Sbjct: 619 RDSSSSTSSSSESRSRSRGRG------------HNRDRKHRRSVDRKRRDTSGLERSHKS 666
Query: 619 SR-SRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
S+ SRD + ++ SRS +R I E R +RS ++DR
Sbjct: 667 SKGGSSRDTKGSKDKNSRSDRKRSI------------------SESSRSGKRSSRSERDR 708
Query: 678 KKKDKERER 686
K K++ R
Sbjct: 709 KSDRKDKRR 717
Score = 75.9 bits (185), Expect = 1e-13
Identities = 119/630 (18%), Positives = 240/630 (38%), Gaps = 98/630 (15%)
Query: 218 KQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME----QQRSQLSKKEKKATED 273
KQ +I + TL + +E ER+K+++ ++++E ++R Q+ + ++ E+
Sbjct: 139 KQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEE 198
Query: 274 --AEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP--VPQEEHSDPEMTEEE 329
A+ + L Q+ + +EE + N + + P +P + EE
Sbjct: 199 RRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEE 258
Query: 330 KEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLG 389
+ +M L + E E+I + R++ K Q+ ++ + G +
Sbjct: 259 SQRKMNALFEGRRIEFA-----EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVA 313
Query: 390 GYGSGDSEDERSDRGSESSDTDDEELRHRI------------RQKQEAFWRKEKEQQLLH 437
E+E + G++ +D + EE ++++E ++E E ++
Sbjct: 314 -----QREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE 368
Query: 438 DKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA-DGDVVNEKKRTPNETTSVLEPK 496
+ ++ E ++Q + +E+ + + +N ++ +E + + V + + NE + LEP+
Sbjct: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPE 428
Query: 497 KEHK-EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS-----------------SYSS 538
E + E +K+ +S S + S+ + S S S
Sbjct: 429 MEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQS 488
Query: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
S S S P+ +P + + + +ES VK+ +
Sbjct: 489 QSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVES----VKLTEVPVEP 544
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
++ E S+ + ++RSRSR R N+ S+SRSR + S +S
Sbjct: 545 VLTVHPE-------SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSS 597
Query: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
R S S +D SS + R + +
Sbjct: 598 SGSSSSRSSSSSSSSTSGSSSRDSSSSTS-----------------SSSESRSRSRGRG- 639
Query: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
H+ + ++S + + SG + S +SS GSS++ K K K+
Sbjct: 640 ---------------HNRDRKHRRSVDRKRRDTSGLERSHKSS--KGGSSRDTKGSKDKN 682
Query: 779 SRS---RSVEKSQRSGKKASRKHKSKSRSR 805
SRS RS+ +S RSGK++SR + + R
Sbjct: 683 SRSDRKRSISESSRSGKRSSRSERDRKSDR 712
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/432 (16%), Positives = 168/432 (38%), Gaps = 42/432 (9%)
Query: 369 PAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWR 428
PAKQ A++ L G+ R R + SD +D++++ Q
Sbjct: 73 PAKQRDLEGAVSRL----------GGERRTRRESR--QESDPEDDDVKKPALQSSVVATS 120
Query: 429 KEKEQQ-LLHDKQMEEE-KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTP 486
KE+ ++ L+ D+ M+E+ KQ+ R+ + + L+ + + V E+++
Sbjct: 121 KERTRRDLIQDQNMDEKGKQRNRRIFGLL----------MGTLQKFKQESTVATERQKRR 170
Query: 487 NETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTS 546
E LE + E + K+ + R + + R ++ + +++
Sbjct: 171 QEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKII 230
Query: 547 SRSSSPKRKKRHSRSRS-PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
++ R+++ P + R ++++ ES R + + RR IE
Sbjct: 231 ----------KYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRR-----IEFA 275
Query: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
+ N+ +R RR+S + + ++ K+ + L ++H + + +E
Sbjct: 276 EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQH-NDVEIEEA 334
Query: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
+E + I +KE+E E+ K++ + K EE+ S+ + + E
Sbjct: 335 GEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE 394
Query: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
++ I + + ++ + + S+ + + E KE K+ P +++
Sbjct: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIE-PDKECKSLSPGKENVSALD 453
Query: 786 KSQRSGKKASRK 797
+ S +K ++
Sbjct: 454 MEKESEEKEEKE 465
Score = 33.5 bits (75), Expect = 0.81
Identities = 44/235 (18%), Positives = 98/235 (41%), Gaps = 34/235 (14%)
Query: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT-----NRASRSRSRDRRKIDDQR 646
R RR S + S + + + + S+ R RR N + + R+RR
Sbjct: 91 RTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIF---- 146
Query: 647 GNLSGNSHKHKGEA----KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDF 702
G L G K K E+ + Q+R++E + ++ +++ K+ E E+ + E+++ ++ +
Sbjct: 147 GLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTEL 206
Query: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ----------DSKKSTTKDSKKHS 752
+ Q L + +E ++ + +K IR ++ + + ++S++
Sbjct: 207 RLLEQKVELAQLQEE---WNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKM 263
Query: 753 GSDSSGR--------SSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
+ GR + E+ + K K+ + R+ + Q GK A R+ +
Sbjct: 264 NALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEE 318
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 100 bits (250), Expect = 4e-21
Identities = 76/224 (33%), Positives = 116/224 (51%), Gaps = 28/224 (12%)
Query: 490 TSVLEP-KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
++ +EP KKE K + + RSRS + SSS + R+ S S S S SR+ R
Sbjct: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSK-------SRSRRR 286
Query: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSR-RIKIESNRARVKIRDR-----RRSNRNSI 602
S SP+R++ HSR R RRSRS S +R + K + + R K + RRS S
Sbjct: 287 SKSPRRRRSHSRERG-----RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR 341
Query: 603 ERERRRNRSPSRERRRSRS------RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
ER RRR+RS +R ++ RS RS R ++ + + +D+ + D+R + K
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
Query: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
K + K++ERK E + + + + D+E EQ EK+K+EEK
Sbjct: 402 KDKEKDRERKSESDKDVKQVTRDYDEE---EQGYDSEKEKKEEK 442
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/298 (28%), Positives = 137/298 (45%), Gaps = 24/298 (8%)
Query: 491 SVLEPKKEHKEKEKQGRS-RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
S ++PK H S +S +SS + R S +S++ R SRS
Sbjct: 192 STVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRS 251
Query: 550 SSPKRKKR------HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
S R++R H RSRS + RRS S+S SRR R R R+R R +R++
Sbjct: 252 RSRSRRRRTPSSSRHRRSRSRS--RRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRST-- 307
Query: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQ 663
+ R + +E++RS++ + T R SRS SR+RR+ + G S K + ++
Sbjct: 308 SKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK--KPRSPKRKL 365
Query: 664 ERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
R R + +K KDKER R++ +R +K++ KD + DR +RK ES++ +
Sbjct: 366 SRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKD----KEKDR-ERKSESDKDVKQ 420
Query: 724 SGSISVKIIRHDSRQDSKKSTTKDSKK-HSGSDSSGRSSSE--SPGSSKEKKAKKPKH 778
++ + DS+K ++ K +GS + S E + S +E K H
Sbjct: 421 ---VTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
Score = 88.6 bits (218), Expect = 2e-17
Identities = 78/283 (27%), Positives = 127/283 (44%), Gaps = 26/283 (9%)
Query: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
S S S TSS + + S + P +K+ K R SRSRS SRR
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEE---------KRRHSRSRSRSRR 257
Query: 580 IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
+ S+ + R R R +S R RRR++SP RRRS SR R RR+ S++R + +
Sbjct: 258 RRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSP--RRRRSHSRERGRRSRSTSKTRDKKK 315
Query: 640 RKIDDQRGNLSGNSH----KHKGEAKEQERKKERS--RSIDKDRKKKDKEREREQDKRKE 693
+ +R S+ + + ++E+ R++ RS RS K R K K +R +
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
Query: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
K+K+++KD K S+D+R ER+ S+ K + + +S K + ++ +
Sbjct: 376 KEKKKDKD-KERSRDER-------ERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
Query: 754 SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASR 796
+ S E K + PK ++ SVEK + S+
Sbjct: 428 EEQGYDSEKEKKEEKKPIETGSPK-TKECSVEKGTGDSLRESK 469
Score = 80.9 bits (198), Expect = 4e-15
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 10/243 (4%)
Query: 563 SPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSR 622
SP++K+ S S+ +K A+ I ++ +R R+RS SR RRR+ S
Sbjct: 207 SPSLKSDTS-SKEIEEAMK-RVREAQSLISAAIEPDKKEEKRRHSRSRSRSR-RRRTPSS 263
Query: 623 SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
SR RR SRSRSR R + S + + + ++E+ R RSRS K R KK +
Sbjct: 264 SRHRR----SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGR---RSRSTSKTRDKKKE 316
Query: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
++E+++ K K + + +S++ R +R R R+ + S K+ R S + KK
Sbjct: 317 DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKK 376
Query: 743 STTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
KD K D RS+S+ S ++K ++ K + V++ R + + + S+
Sbjct: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 803 RSR 805
+
Sbjct: 437 EKK 439
Score = 35.8 bits (81), Expect = 0.16
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 196 QNRRERPSS-FRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKE 254
+ RR R +S RD+++ + PP+ + RR+ A RE + R + +K
Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA-SRERRRRRSRSGTRSPKKP 358
Query: 255 RMEQQRSQLS------KKEKKATEDAEGG--DGPRLPQRSKFDSDEEEEDTENVEAASSG 306
R +++ S KKEKK +D E + R + K D+E++ E+
Sbjct: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
Query: 307 K-VTRSPSPVPQEEHSDPEMTEEEK 330
K VTR Q S+ E EE+K
Sbjct: 419 KQVTRDYDEEEQGYDSEKEKKEEKK 443
Score = 33.9 bits (76), Expect = 0.62
Identities = 38/178 (21%), Positives = 66/178 (37%), Gaps = 18/178 (10%)
Query: 359 KDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
+D +K +K P K + + S S + RS G+ S R
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRS----------ASRERRRRRSRSGTRSPKKPRSPKRKL 365
Query: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
R +KEK++ DK E + + ER T + + KE++ E +
Sbjct: 366 SRSPSPRRHKKEKKK----DKDKERSRDERERSTSKKKKSKDKEKDR----ERKSESDKD 417
Query: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
V + R +E + +KE KE++K + S + S + S S V+ +
Sbjct: 418 VKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDH 475
Score = 33.1 bits (74), Expect = 1.1
Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 727 ISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEK 786
++ ++ + D+ +++ K S S++ P +EK+ +HSRSRS +
Sbjct: 201 VAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKR----RHSRSRSRSR 256
Query: 787 SQRSGKKASRKHKSKSRSR 805
+R+ +SR +S+SRSR
Sbjct: 257 RRRT-PSSSRHRRSRSRSR 274
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/173 (17%), Positives = 57/173 (32%), Gaps = 8/173 (4%)
Query: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
S R S + R R +E R + K+ ++EK++++ K
Sbjct: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
+ S R G +K R+P S + HK+++K+ + + S
Sbjct: 331 STARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE 390
Query: 516 GSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS--------SSPKRKKRHSR 560
S++ + S S S + +R S K KK +
Sbjct: 391 RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 100 bits (248), Expect = 7e-21
Identities = 72/227 (31%), Positives = 110/227 (48%), Gaps = 18/227 (7%)
Query: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSR 560
+ E+ G + +S S S S YS S SR R S + +K SR
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 561 SRSPTIKARRSRSRSYSRRIKIESN---RARVKIRDRRRSNRNSIERERRRNRSPSRERR 617
SRS + S+ +S + E N + K R+R S+ N +R +R+ R SR R
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
SRSRSR+RR RSRSR+R+K + S + + K ++ +ERKK RSRS ++ R
Sbjct: 125 HSRSRSRERR----HRSRSRERKK------SRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Query: 678 KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRS 724
+ + + R R + + + + + + S DR K++ E R FSRS
Sbjct: 175 RIRSRSRSRSRHRHRTRSRSRTR----SRSRDR-KKRIEKPRRFSRS 216
Score = 89.7 bits (221), Expect = 9e-18
Identities = 59/183 (32%), Positives = 89/183 (48%), Gaps = 23/183 (12%)
Query: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
K +++ ++ + RSRS S S S + +SS G R +S + R
Sbjct: 53 KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH 112
Query: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
KR R K+ R RS S SR S R + R R R S RER+++RS SRE
Sbjct: 113 KRKER------KSSRGRSHSRSR-----SRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
Query: 616 RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDK 675
R++SRSRSR+R+ SRSRSR R + H+ + ++ + R ++R + I+K
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHR------------HRTRSRSRTRSRSRDRKKRIEK 209
Query: 676 DRK 678
R+
Sbjct: 210 PRR 212
Score = 83.6 bits (205), Expect = 7e-16
Identities = 79/268 (29%), Positives = 132/268 (49%), Gaps = 33/268 (12%)
Query: 442 EEEKQQTE-RVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHK 500
+++K+Q+E V+ ++ + S S R++D + + R+ ++ E K +
Sbjct: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
Query: 501 EKEK--QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRH 558
+K K + + SS G NS + + SS G S + SRS ++R
Sbjct: 81 KKHKSEEHNDKEHSSDKGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRS-----RERR 134
Query: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR-RNRSPSRERR 617
RSRS K RSRSR E ++R + R+R++S S ER+RR R+RS SR R
Sbjct: 135 HRSRSRERKKSRSRSR--------ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 186
Query: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK------HKGEAKEQERKKERSR 671
R R+RSR R +RSRSRDR+K ++ S + + +G + ++ +R
Sbjct: 187 RHRTRSRSR-----TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
Query: 672 SIDKDRKKKDKEREREQDKRKEKQKREE 699
+++ KK ++RE+E EKQK++E
Sbjct: 242 RLER-AKKLQEQREKEM---VEKQKQQE 265
Score = 78.2 bits (191), Expect = 3e-14
Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 18/196 (9%)
Query: 611 SPSRERRRSRSR-SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
SP R++++ +S S R ++ SRSR R + ++ + G H+ + +KE R + +
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
Query: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
+S K + ++ ++E DK +E+ E + R +RK R+ SRS S
Sbjct: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENG---EDRHKRKERKSSRGRSHSRSRS--- 130
Query: 730 KIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQR 789
+ RH SR +K + S++ S S R +S S+E+K + SRSRS
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS------ 184
Query: 790 SGKKASRKHKSKSRSR 805
+H+++SRSR
Sbjct: 185 -----RHRHRTRSRSR 195
Score = 75.9 bits (185), Expect = 1e-13
Identities = 66/264 (25%), Positives = 124/264 (46%), Gaps = 23/264 (8%)
Query: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
+SP R K+ + +S + R+ YSR +R + R+R+R + N E R++
Sbjct: 16 TSPDRDKK--KEQSEVSVSPRASKHHYSR--------SRSRSRERKRKSDN----EGRKH 61
Query: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
RS SR + R S+D+ + + D+ D+ +S + K +ERK R
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
Query: 670 SRSIDKDRKKKDKEREREQDKRKEKQK-REEKDFKFSSQDDRLKRKRESERTFS-RSGSI 727
RS + R ++ + R R ++++K + + RE K + S++ + R R ER RS S
Sbjct: 122 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
Query: 728 SVKIIRHDSRQDSK-KSTTKDSKK-----HSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
S RH +R S+ +S ++D KK S S R+ S P + A + + +
Sbjct: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR-NTAMDAQEALA 240
Query: 782 RSVEKSQRSGKKASRKHKSKSRSR 805
R +E++++ ++ ++ K + +
Sbjct: 241 RRLERAKKLQEQREKEMVEKQKQQ 264
Score = 58.2 bits (139), Expect = 3e-08
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 662 EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
E++ S D+D+KK+ E K R S+ KRK ++E
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSR------SRSRERKRKSDNEGRK 60
Query: 722 SRSGSISVKIIRHDSRQDSK---KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP-- 776
RS S S + RH+S+ S KS + K+HS R +S G + K+ ++
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 777 ---KHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
HSRSRS E+ RS + +K +S+SR R
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
Score = 39.3 bits (90), Expect = 0.015
Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 400 RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEK-QQTERVT---KEM 455
RS G D +H+ + + +K ++ L+ + E++ ++ ER + +
Sbjct: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 125
Query: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
+ +E+ S R+ E+K++ + + + + +E++++ RSRS S S
Sbjct: 126 SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
Query: 516 GS--SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
+ S SRT S S SR+ SR+ SP R R+ + A+ + +
Sbjct: 186 HRHRTRSRSRTRSRSRD-RKKRIEKPRRFSRSLSRTPSPP----PFRGRNTAMDAQEALA 240
Query: 574 RSYSRRIKIESNRARVKIRDRRR 596
R R K++ R + + +++
Sbjct: 241 RRLERAKKLQEQREKEMVEKQKQ 263
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 98.2 bits (243), Expect = 3e-20
Identities = 86/270 (31%), Positives = 123/270 (45%), Gaps = 34/270 (12%)
Query: 535 SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDR 594
S S SR+ SRS S KR KR RRSRSR RR R R + RD+
Sbjct: 12 SASRGRSGSRSRSRSPSDKRSKRGD--------DRRSRSRDRDRR------RERSRSRDK 57
Query: 595 RRS---NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSG 651
RRS +R + R R R R SRERRRSRSR R R SRSRSR RR GN
Sbjct: 58 RRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR-----RRSRSRSRGRRSRSSSPGN--- 109
Query: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
S K + ++ +E+ S +K + K DKE E+E+D Q + E++ + + +R+
Sbjct: 110 KSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMR--KRKERV 167
Query: 712 KRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSS--- 768
++ RE +R + +K + +Q K S D + + +E G
Sbjct: 168 EKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDP 227
Query: 769 ----KEKKAKKPKHSRSRSVEKSQRSGKKA 794
E+ ++ K RSV+ + KK+
Sbjct: 228 LDAYMEEVKEEVKKFNMRSVKGGGGNEKKS 257
Score = 85.1 bits (209), Expect = 2e-16
Identities = 77/277 (27%), Positives = 119/277 (42%), Gaps = 20/277 (7%)
Query: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
+ H K R RSGS S S S+ R+ S S R R S R
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSR-------DRDRRRERSRSRD 56
Query: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
KR SRSR + RRSRSR R R R + RDRRRS S R R R+ SP +
Sbjct: 57 KRRSRSRDRK-RLRRSRSRERDR----SRERRRSRSRDRRRSRSRSRGR-RSRSSSPGNK 110
Query: 616 RRRSRSRSRDRRT---NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRS 672
+++ +RSR + +S+ + +D+ +D++ +GN ++K E +E ++KER
Sbjct: 111 SKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLE-EEMRKRKERVEK 169
Query: 673 IDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKII 732
++++KK E E K E+ K+ +K + DD E+E+ + + +
Sbjct: 170 WREEQRKKAMENIGELKKEIEEMKQGKK-WSLEDDDDDEDDPAEAEKEGNEMEGEELDPL 228
Query: 733 RHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSK 769
D+ + K K S G P +K
Sbjct: 229 --DAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTK 263
Score = 71.6 bits (174), Expect = 3e-12
Identities = 59/204 (28%), Positives = 94/204 (46%), Gaps = 34/204 (16%)
Query: 603 ERERRRNRSPSRERRRSRSRSR---DRRTNRAS--RSRSRDRRKIDDQRGNLSGNSHKHK 657
E R RS SR R SRSRSR D+R+ R RSRSRDR D+R
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDR----DRR----------- 48
Query: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRES 717
+E+ R +++ RS +DRK+ + R RE+D+ +E+++ +D + S R +R
Sbjct: 49 ---RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRR---- 101
Query: 718 ERTFSRSGSISVKIIRHDSRQDSKKST---TKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
SRS S K + ++R SK+ T +K D + G+ + K +
Sbjct: 102 ----SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLE 157
Query: 775 KPKHSRSRSVEKSQRSGKKASRKH 798
+ R VEK + +K + ++
Sbjct: 158 EEMRKRKERVEKWREEQRKKAMEN 181
Score = 59.7 bits (143), Expect = 1e-08
Identities = 59/198 (29%), Positives = 82/198 (41%), Gaps = 63/198 (31%)
Query: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQ 663
RE R R S R RS SRSR SRS S R K D R
Sbjct: 3 RESRHYRKRSASRGRSGSRSR-------SRSPSDKRSKRGDDR----------------- 38
Query: 664 ERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
RSRS D+DR++ ER R +DKR+ + + + RL+R R ER
Sbjct: 39 -----RSRSRDRDRRR---ERSRSRDKRRSRSRDRK----------RLRRSRSRER---- 76
Query: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
D ++ ++S ++D ++ RS S SPG+ +K +RSRS
Sbjct: 77 -----------DRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK-----TENRSRS 120
Query: 784 VEKSQRSGKKASRKHKSK 801
EK+ G+ + K K K
Sbjct: 121 KEKTD-GGESSKEKKKDK 137
Score = 45.4 bits (106), Expect = 2e-04
Identities = 70/325 (21%), Positives = 120/325 (36%), Gaps = 63/325 (19%)
Query: 471 AREADGDVVNEKKRTPNETTSVLEPKKE--HKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
+R D D E+ R+ ++ S +K ++ RSR S SR
Sbjct: 40 SRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSR----- 94
Query: 529 STVSSSSYSSSSGSSRTSSRSSSP--KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586
S S SRSSSP K KK +RSRS K + S + K + ++
Sbjct: 95 -----------SRSRGRRSRSSSPGNKSKKTENRSRS---KEKTDGGESSKEKKKDKDDK 140
Query: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646
K +D ++N +E E R +R R + R R+K +
Sbjct: 141 EDEKEKDAGNFDQNKLEEEMR------------------KRKERVEKWREEQRKKAMENI 182
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE-----------QDKRKEKQ 695
G L K E +E ++ K+ S D D + E E+E D E+
Sbjct: 183 GEL-------KKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEV 235
Query: 696 KREEKDFKFSSQDDRLKRKRESERTFSRSGSI---SVKIIRHDSRQDSKKSTTKDSKKHS 752
K E K F S +++S T ++ ++ ++ D ++ +D+ ++S
Sbjct: 236 KEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYS 295
Query: 753 GSDSSGRSSSESPG-SSKEKKAKKP 776
+ + G +K++K +P
Sbjct: 296 SEEEEVDLQTALTGYQTKQRKLLEP 320
Score = 44.3 bits (103), Expect = 5e-04
Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 26/143 (18%)
Query: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722
+E + R RS + R DKR ++ DDR R R+ +R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRG------------DDRRSRSRDRDRRRE 50
Query: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSR 782
RS S +D ++S ++D K+ S S R S S+ + ++ SRSR
Sbjct: 51 RSRS-----------RDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRR---SRSR 96
Query: 783 SVEKSQRSGKKASRKHKSKSRSR 805
S + RS ++ K+++RSR
Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSR 119
Score = 34.7 bits (78), Expect = 0.36
Identities = 62/331 (18%), Positives = 115/331 (34%), Gaps = 46/331 (13%)
Query: 393 SGDSEDERSDRG----SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQT 448
S D+RS RG S S D D R R R K+ + R ++L + E ++ +
Sbjct: 24 SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS--RSRDRKRLRRSRSRERDRSRE 81
Query: 449 ERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
R R D + R+ + P +K K+ + RS
Sbjct: 82 RR---------------------RSRSRDRRRSRSRSRGRRSRSSSP--GNKSKKTENRS 118
Query: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
RS + G SS + + + KRK+R + R +
Sbjct: 119 RSKEKTDGGESSKEKKKDKDDK-EDEKEKDAGNFDQNKLEEEMRKRKERVEKWR----EE 173
Query: 569 RRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSR-ERRRSRSRSRDRR 627
+R ++ +K E I + ++ + S+E + P+ E+ + +
Sbjct: 174 QRKKAMENIGELKKE-------IEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
Query: 628 TNRASRSRSRDRRKIDDQRGNLSGNSHKHKG---EAKEQERKKERSRSIDKDRKKKDKER 684
A ++ K + R G ++ K K + +D D KKK +
Sbjct: 227 PLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSD-KKKGELM 285
Query: 685 EREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
E +QD + + EE D + + + K+++
Sbjct: 286 ENDQDAMEYSSEEEEVDLQTALTGYQTKQRK 316
Score = 32.3 bits (72), Expect = 1.8
Identities = 32/148 (21%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 189 PGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQ 248
PG + R R D S + K++ + K + + + LE+ R+++
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGES--SKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK 164
Query: 249 KKLEKERMEQQRSQLSK--KEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSG 306
+++EK R EQ++ + + KK E+ + G ++ + D+++ED + EA G
Sbjct: 165 ERVEKWREEQRKKAMENIGELKKEIEEMKQG------KKWSLEDDDDDED-DPAEAEKEG 217
Query: 307 KVTRSPSPVPQEEHSDPEMTEEEKEYQM 334
P + + + E+ EE K++ M
Sbjct: 218 NEMEGEELDPLDAYME-EVKEEVKKFNM 244
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 96.7 bits (239), Expect = 8e-20
Identities = 140/588 (23%), Positives = 236/588 (40%), Gaps = 91/588 (15%)
Query: 289 DSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348
+ + E+ ++N + K + S + +HS E +++K+++ K + ++D
Sbjct: 28 NGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEE--DKDKKHKHKHKHKKHKRKEIID 85
Query: 349 VTDEEIYYVAK-------------DAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGD 395
+D+E AK + R KA + S GL L GY SG
Sbjct: 86 ASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLI-LQGYESGS 144
Query: 396 SED----ERSDRGSESSDTDD------EELRHRIRQKQEAFWRKEKEQQLLHDKQ----- 440
E+ E++ G+ SS E + ++I K+ + R ++ + DK+
Sbjct: 145 EEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGG 204
Query: 441 MEEEKQQTERV-TKEMNEFIHKEQNSLSLLEAREADGDVVNE-------KKRTPNETTSV 492
+E K++T R +KE + + S S +AR++ + K R+P +
Sbjct: 205 IEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVK 264
Query: 493 LEPKKEHKEKEK-----QGRSRS------------GSSSSGSSSSNSRTSSTSST----- 530
+E K + K+++K + RSR G S S S R S S T
Sbjct: 265 IEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKK 324
Query: 531 -VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARV 589
+ S S +SSG S + KR S S P K+RRSRS + R +S
Sbjct: 325 PIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSR 384
Query: 590 KIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID----DQ 645
+ RR+ S+ER+R R P R RR S R+R R + R RS+D I+ +
Sbjct: 385 TLSPGRRAKSRSLERKR---REPER-RRLSSPRTRPRDDILSRRERSKDASPINRWSPTR 440
Query: 646 RGNLSGNSHKHKGEAKEQERKKERSRS---IDKDRKKKDKEREREQDK--RKEKQKREEK 700
R + S + + + + RSRS D+ R+ + + R R + + R+ + + + K
Sbjct: 441 RRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVK 500
Query: 701 DFKF-------------SSQDDRLKR---KRESERTFSRSGSISVKIIRHDSRQDSKKST 744
+ KF SS DD L+ + E E I + I + ++ S
Sbjct: 501 EDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSN 560
Query: 745 TKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGK 792
+ S SS R+ S SP E+ A K +V+ + S K
Sbjct: 561 MSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVK 608
Score = 91.3 bits (225), Expect = 3e-18
Identities = 111/480 (23%), Positives = 207/480 (43%), Gaps = 83/480 (17%)
Query: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
D+ E+S ++D+ R K++ + K ++ H + +++K K
Sbjct: 17 DANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDK-------KH 69
Query: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEP--------KKEHKEKEKQG 506
++ HK+ +++A + +G ++ KRT + ++LE K E + +G
Sbjct: 70 KHKHKHKKHKRKEIIDASDKEG--MSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEG 127
Query: 507 RSRSG-----------SSSSGSSSSNSRTSSTSSTVSSSSYSSSS-GSSRTSSRSSSPKR 554
+ +SG S G +R + SST SSS+ ++ +++ S R
Sbjct: 128 KVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSR 187
Query: 555 KKRHSRSRSPT---------IKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
K +R RS +K + +RS+S R+ K +S R K +D+ R +++ R
Sbjct: 188 SKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERK-KSKSPSKRSKSQDQARKSKSPTLRR 246
Query: 606 RRRN-----RSPSRERRR--SRSRSRDRRTNRA-SRSRSRDRRKIDDQRGNLSGNSHKHK 657
R + RSP+ ++ + +S+S+DR+ + + SRSRDR K +L G S +
Sbjct: 247 RSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRR 306
Query: 658 GEAKEQERKKE-------------RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKF 704
+KE++ K+ + S K+ + + R +R K +K +
Sbjct: 307 SRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRS 366
Query: 705 SS---QDDRLKRKRESERTFS---RSGSISVKIIRHDS---RQDSKKSTTKD---SKKHS 752
S D R K+ + RT S R+ S S++ R + R S ++ +D S++
Sbjct: 367 RSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRER 426
Query: 753 GSDSSG-------RSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
D+S R S SP ++++ P RSRS + RS ++ R +S+SR R
Sbjct: 427 SKDASPINRWSPTRRRSRSP---IRRRSRSPLR-RSRSPRRRSRSPRRRDRGRRSRSRLR 482
Score = 35.0 bits (79), Expect = 0.28
Identities = 70/351 (19%), Positives = 134/351 (38%), Gaps = 48/351 (13%)
Query: 187 GPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMERE 246
G P + + E S +DR++SPI E D K+ P +R G K R
Sbjct: 253 GKARSPTDDKVKIEDKSKSKDRKKSPII----NESRSRDRGKKSRSPVDLR-GKSKDRRS 307
Query: 247 KQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQR-----------SKFDSDEEEE 295
+ K+ + +R E + + K K ++DA G R P R S D+
Sbjct: 308 RSKERKSKRSETDKEK--KPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRR 365
Query: 296 DTENVEAASSGKVTRSP----SPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTD 351
+ K ++SP SP + + E E E + + + + +L +
Sbjct: 366 SRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRE 425
Query: 352 EEIYYVAKDAH--------RKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDR 403
+KDA R+ +++P ++ ++S S + R DR
Sbjct: 426 R-----SKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSP-------RRRSRSPRRRDR 473
Query: 404 GSESSDTDDEELRHR--IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK 461
G S R R R++ + +++K + L + E++ ++ + +F +
Sbjct: 474 GRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSD---DNLEDFDVE 530
Query: 462 EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGS 512
E++ +L+E R + +K + E +++ P E + R+RS S
Sbjct: 531 EEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVP-SEPSSPQSSTRTRSPS 580
Score = 30.0 bits (66), Expect = 8.9
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 33/175 (18%)
Query: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKR--EEKDFKFSSQDDRLKRKRESER- 719
++ E+S + + +D+ + + +K+K K + K K SS++D+ K+ + +
Sbjct: 16 EDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKH 75
Query: 720 ----------TFSRSGSISVKIIRHD--------SRQDSKKSTTKDSKKHSGSDSSG--- 758
+ G K + D +Q + D++ G SG
Sbjct: 76 KKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGL 135
Query: 759 -----RSSSESPGSSKEKKAKKPKHSRSRSVE---KSQRSGKKASRKHKSKSRSR 805
S SE G E KA+ S +RS K + K + K +SKSRS+
Sbjct: 136 ILQGYESGSEEEGEIHE-KARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSK 189
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 95.5 bits (236), Expect = 2e-19
Identities = 100/480 (20%), Positives = 191/480 (39%), Gaps = 43/480 (8%)
Query: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDT 410
D++ A++ R+A + +Q + +L +T + S E+ ++ + +
Sbjct: 31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 411 DDEEL-------RHRIRQK--QEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK 461
DDE R RQK QEA R+++ + D + ++ + T E NE K
Sbjct: 91 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE-NETTEK 149
Query: 462 EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-- 519
E+ S S E E + K N+ E KKE KEKE++ + S G +
Sbjct: 150 EEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVE 209
Query: 520 ---SNSRTSSTSSTVSSSSYSSS-------------SGSSRTSSRSSSPKRKKRHSRSRS 563
T S TV S + GS S + K + +
Sbjct: 210 VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAER 269
Query: 564 PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRS 623
++A + KI RAR++ ++ + ERERR R R + +
Sbjct: 270 ARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ----ERERREAEERERMREEEKRAA 325
Query: 624 RDR-RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
+R R + + +R++I ++ + + K E K +++R+R+ +++ K K +
Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA-EEEEKAKVE 384
Query: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
E++R + ++K +E K + +++ K +E+ ++ + +++ +Q +K
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK-AQEDKLQTAVLK---KQGEEK 440
Query: 743 STTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
T +K+ + E K KK K+PK KS KK + KS++
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE-----VKSFMDRKKGFTEVKSQN 495
Score = 73.9 bits (180), Expect = 5e-13
Identities = 81/426 (19%), Positives = 170/426 (39%), Gaps = 46/426 (10%)
Query: 411 DDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLE 470
DD E R +R+++ R E E+ +EE+ ER + E + ++Q SL +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 471 ARE-----ADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTS 525
+ A V +E+ +T T V E E E+ R R + R
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQV-EGDDEAAFLERLAR-REERRQKRLQEALERQK 119
Query: 526 STSSTVSSSSYS--SSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYS------ 577
T++ +S S S + T+ ++ K +K SR I+ + ++SY
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 578 -------------------RRIKIESNRARVKIRDR-RRSNRNSIERERRRNRSPSRERR 617
+R I N+ V + ++ S ++ + + S E +
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK 239
Query: 618 RSRSRSR-DRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD 676
+ R + + + D+ + + +R L + ++++ ER+R I+ +
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR-IEAE 298
Query: 677 RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDS 736
K +ERER + + +E+ + EEK + ++R + K E + R+ +I +
Sbjct: 299 EKAAAQERERREAEERERMREEEK----RAAEERQRIKEEEK----RAAEERQRIKEEEK 350
Query: 737 RQDSKKSTTKDSKKHSGSD-SSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKAS 795
R ++ K+ +K + + R+ E +E+K K + ++++++ G+K
Sbjct: 351 RAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Query: 796 RKHKSK 801
+K + K
Sbjct: 411 QKIEGK 416
Score = 72.8 bits (177), Expect = 1e-12
Identities = 94/582 (16%), Positives = 226/582 (38%), Gaps = 80/582 (13%)
Query: 241 EKMEREKQKKLEKERMEQQRSQLS------KKEKKATEDAEGGDGPRLPQRSKFDSDEEE 294
E+ RE++++ +ER+ Q++ + S + E A + ++ + D+E
Sbjct: 35 EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA 94
Query: 295 EDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEI 354
E + + R + +++ DP +T+
Sbjct: 95 AFLERLARREERRQKRLQEALERQKEFDPTITD--------------------------- 127
Query: 355 YYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEE 414
+ P++++ +A T ++E+S+ E + ++ E
Sbjct: 128 ---------ASLSLPSRRMQNDTAENETT------------EKEEKSESRQERYEIEETE 166
Query: 415 LRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTER---VTKEMNEFIHKEQNSLSLLEA 471
+ QK + WR + E+ DK+ EEE+++ + + + E + +E+ + S E
Sbjct: 167 TVTKSYQKND--WR-DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET 223
Query: 472 ---READGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
+G + +E+ + E + H++ E++ + R+ + + +
Sbjct: 224 VVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAE 283
Query: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA- 587
+ ++++ +R++R + R ++ R+ +RIK E RA
Sbjct: 284 ---QDKKIADERARIEAEEKAAAQERERREAEERE-RMREEEKRAAEERQRIKEEEKRAA 339
Query: 588 --RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDR-RTNRASRSRSRDRRKIDD 644
R +I++ + +R + + + ER+R+R+ ++ + R++ + +K
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399
Query: 645 QRGNLSGNSHKHKGEAK-EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
Q + G + K E K E+K + + KK+ +E+ + ++EK + ++ FK
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459
Query: 704 FSS-QDDRLKRKRESERTFS-----RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS 757
+D+++K+ +E + + G VK + K T + G S
Sbjct: 460 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASV 519
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
+ E+ G+ + + K+ + R R E +K +K +
Sbjct: 520 --DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ 559
Score = 69.3 bits (168), Expect = 1e-11
Identities = 95/516 (18%), Positives = 201/516 (38%), Gaps = 43/516 (8%)
Query: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
E E +K EK Q+R ++ + E T+ + D + K D ++EEE+ E +
Sbjct: 143 ENETTEKEEKSESRQERYEIEETET-VTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
S G+ + V EE + TE ++E +M L ++ +E + +H
Sbjct: 202 SIGE---NQVEVMVEEKT----TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 364 KATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQ 423
+ + K+ A++ ++E+ + + DE R +K
Sbjct: 255 EKMEEEDKERAEAERARL-------------EAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 424 EAFWRKEKEQQLLHDKQMEEEKQQTE--RVTKEMNEFIHKEQNSLSLLEAREADGD--VV 479
A R+ +E + ++ EEEK+ E + KE + +E+ + E R A+ +
Sbjct: 302 AAQERERREAEE-RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIK 360
Query: 480 NEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSS 539
E+KR E + E +EK K + + T V
Sbjct: 361 EEEKRAAEERQRA---RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW 417
Query: 540 SGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR 599
+ K+ + ++A+R + + K E + +D+
Sbjct: 418 VNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 477
Query: 600 NSIERERRRN----RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDD----QRGNLSG 651
+R++ +S + E + + + +R S D ++ + + G
Sbjct: 478 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 537
Query: 652 NSHKHKGEAKEQE----RKKERSRSID-KDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
+ +GE + +E ++K++ +++ ++ KKK +ER + ++ ++++K+EE D K
Sbjct: 538 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLRE 597
Query: 707 QDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
++++ + K E ER + + K + D D KK
Sbjct: 598 EEEKRRLKEEIERRRAEAAEKRQK-MPEDGLSDDKK 632
Score = 48.1 bits (113), Expect = 3e-05
Identities = 70/409 (17%), Positives = 147/409 (35%), Gaps = 63/409 (15%)
Query: 237 REGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEED 296
R LE ERE+ K + +++ +R+++ +EK A ++ E R + + E +
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERE---------RREAEERERMRE 319
Query: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
E A ++ +E + EEEK EE
Sbjct: 320 EEKRAAEERQRIKEEEKRAAEERQ---RIKEEEKR------------------AAEERQR 358
Query: 357 VAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELR 416
+ K+ ++A + + A+ A + E+++ ++ E +E +
Sbjct: 359 I-KEEEKRAAEERQRARAEEEEKAKV--------------EEQKRNKQLEEKKHAMQETK 403
Query: 417 ---HRIRQKQEAFWRKEKEQQLLHDK-QMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAR 472
++ QK E W EK+ Q DK Q K+Q E ++ K Q +
Sbjct: 404 IKGEKVEQKIEGKWVNEKKAQ--EDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461
Query: 473 EADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVS 532
E + + + K E S ++ KK E +S++G + T S +
Sbjct: 462 EIKDEKIKKDKEPKEEVKSFMDRKKGFTEV----KSQNGEFMTHKLKHTENTFSRPGGRA 517
Query: 533 SSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR 592
S + G+ + + + ++R + S + + + + + ++ +++
Sbjct: 518 SVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE--------ELK 569
Query: 593 DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRK 641
+R R +E E +R + +R+ + R R R+ K
Sbjct: 570 KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/228 (14%), Positives = 92/228 (40%), Gaps = 25/228 (10%)
Query: 602 IERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAK 661
+ER RR + + + R ++ S S R++ + + K E++
Sbjct: 97 LERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESR 156
Query: 662 EQERKKERSRSIDK-----------DRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDR 710
++ + E + ++ K + KK+DKE+E E++++ ++ E + ++
Sbjct: 157 QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKT 216
Query: 711 LKRKRESERTFSRSGSISV--------------KIIRHDSRQDSKKSTTKDSKKHSGSDS 756
+ + E+ ++G IS +I H+ ++ K + + ++
Sbjct: 217 TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE 276
Query: 757 SGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
R +E +++A+ ++ + E+ +R ++ R + + R+
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324
Score = 38.5 bits (88), Expect = 0.025
Identities = 71/336 (21%), Positives = 133/336 (39%), Gaps = 64/336 (19%)
Query: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLE 252
A Q R R + R+R R +E + ++R I+E ++ E+Q+ E
Sbjct: 301 AAAQERERREAEERERMR--------EEEKRAAEERQR-----IKEEEKRAAEERQRIKE 347
Query: 253 KE-RMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRS 311
+E R ++R ++ ++EK+A E+ QR++ EEE+ VE K
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEER---------QRAR----AEEEEKAKVEEQKRNKQLEE 394
Query: 312 PSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAK 371
QE E E++ E + + K ++ V + K K TK AK
Sbjct: 395 KKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAV-------LKKQGEEKGTKVQAK 447
Query: 372 --QLAQSSALASLTGLGGLGGYGSGDSEDE------RSDRGSESSDTDDEELRHRIRQKQ 423
+L + + + ++E R +E + E + H+++ +
Sbjct: 448 REKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTE 507
Query: 424 EAFWR---------KEKE--QQLLHDKQMEE-EKQQTERVTKEMNEFIHKEQNSLSLLEA 471
F R KE E Q+ K++EE +++ E ++E + K+Q + LE
Sbjct: 508 NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE- 566
Query: 472 READGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGR 507
E K+ E VLE +++ +++E+ R
Sbjct: 567 ---------ELKKKREERRKVLEEEEQRRKQEEADR 593
Score = 36.6 bits (83), Expect = 0.095
Identities = 62/361 (17%), Positives = 140/361 (38%), Gaps = 22/361 (6%)
Query: 198 RRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME 257
+ E + +RQR +K+E + A +R+ + + E+ +R + ++ EK ++E
Sbjct: 332 KEEEKRAAEERQR------IKEEEKRA-AEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 258 QQRSQLSKKEKKATEDAEGGDGPRLPQR------SKFDSDEEEEDTENVEAASSGKVTRS 311
+Q+ +EKK G ++ Q+ ++ + E++ T ++ K T+
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 312 PSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAK 371
+ + + P +EE + + + K E+ + ++ + K + + K
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 372 QLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWR-KE 430
+ + GG S D+++ E+ +E R R + E F + K+
Sbjct: 505 HTENTFSRP--------GGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQ 556
Query: 431 KEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETT 490
K+Q+ + + ++K++ R E E K++ + L E + E +R E
Sbjct: 557 KQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 616
Query: 491 SVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSS 550
+ E + + + + S R + +V SS S+ + S+
Sbjct: 617 EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKID 676
Query: 551 S 551
S
Sbjct: 677 S 677
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 95.1 bits (235), Expect = 2e-19
Identities = 87/286 (30%), Positives = 134/286 (46%), Gaps = 18/286 (6%)
Query: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPK 553
+ ++E + K K+ R SSSS SS+SRT S S S S S RS S
Sbjct: 7 DTEEESRSKRKKKHRRRSSSSS---SSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYD 63
Query: 554 RKKRHSRSRSPTIKARRSRSRSYSRRI--KIESNRARVKIRDRRRSNRNSIERERRRNRS 611
R++RH S S + +RR RSRS SR R+R K R RR +R + R +
Sbjct: 64 RRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSER 123
Query: 612 PSRERRRSRSRSRDRRTNRASRSRSRDRRKIDD------QRGNLSGNSHKHKGEAKEQER 665
S R RSRSR R+RR R R +++ K D +RG SGN E+
Sbjct: 124 SSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGE-SGNIKAGLEHLPPAEQ 182
Query: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
K R + + + K D+ + ++ +E ++R+E+D ++ +++KR +E E S
Sbjct: 183 AKARLQLVLEAAAKADEALKAKERNEEEAKRRKEED--QATLVEQVKRVKEIEAI--ESD 238
Query: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK 771
S + R S ++ KKS K + S S S+ P S++++
Sbjct: 239 SFVQQTFR--SSKEVKKSVEPSEVKQATSTSGPASAVADPPSTEKE 282
Score = 83.2 bits (204), Expect = 9e-16
Identities = 70/224 (31%), Positives = 112/224 (50%), Gaps = 16/224 (7%)
Query: 542 SSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNS 601
SS T S S KRKK+H R S + S SR+YSR+ +R++ + R R+
Sbjct: 5 SSDTEEESRS-KRKKKHRRRSS---SSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSH 60
Query: 602 IERERRRNRSPS-----RERRRSRSRSRDR-RTNRASRSRSRDRRKIDDQRGNLSGNSHK 655
RRR+RS S R+RSRSRSR R ++ R RSRS+ R + R L
Sbjct: 61 SYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRL----RS 116
Query: 656 HKGEAKEQERKKERSRSIDKDRKK-KDKE-REREQDKRKEKQKREEKDFKFSSQDDRLKR 713
H ++ ++ RSRS D++R+K +DKE RE+E+DK K+K+ K + + L+
Sbjct: 117 HSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEH 176
Query: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS 757
+E+ +R + + D +K+ +++K+ D +
Sbjct: 177 LPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQA 220
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 16/168 (9%)
Query: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKR 697
RR D + + S KH+ + R+ S K RK + K R +D +
Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSY 62
Query: 698 EEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS 757
+ + SS +R+ R+ SR S ++ R S+ +++S ++ + S S SS
Sbjct: 63 DRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRP-RLRSHSRSS 121
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
RSS + +RSRS ++ +R G+ ++ K K + +
Sbjct: 122 ERSSH--------------RRTRSRSRDRERRKGRDKEKREKEKDKGK 155
Score = 35.4 bits (80), Expect = 0.21
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQR--SGKKASRKHKSKSRS 804
GR SS++ S+ K+ KK + S S R S KK RK +SKSRS
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRS 50
Score = 31.6 bits (70), Expect = 3.1
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 406 ESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNS 465
E++ DE L+ + R ++EA RKE++Q L +E+ K+ E E + F+ + S
Sbjct: 192 EAAAKADEALKAKERNEEEAKRRKEEDQATL----VEQVKRVKEIEAIESDSFVQQTFRS 247
Query: 466 LSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501
++ + + V + T ++V +P KE
Sbjct: 248 SKEVK-KSVEPSEVKQATSTSGPASAVADPPSTEKE 282
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 94.4 bits (233), Expect = 4e-19
Identities = 122/614 (19%), Positives = 242/614 (39%), Gaps = 84/614 (13%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
+ R E+ R+RQ V QE + + KR T+ E L++ E ++Q++L++E
Sbjct: 221 KGREEKQQQRRERQDR-----VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE- 274
Query: 256 MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPV 315
E+Q +L ++E + E RL + + +EEE E E + R
Sbjct: 275 -EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ--- 330
Query: 316 PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQ 375
QEE + ++ E++E + L + ++ R+ + +Q
Sbjct: 331 -QEERREQQLRREQEERREQQLRR------------------EQEEERREQQLRREQ--- 368
Query: 376 SSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE----K 431
E+ER ++ +++LR + ++E R+E +
Sbjct: 369 ---------------------EEERREQQLRR----EQQLRREQQLRREQQLRREQQLRR 403
Query: 432 EQQLLHDKQMEEEKQ--QTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNET 489
EQQL ++Q+ E+Q + +++ +E E H++++ E R KR E
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR---------LKREQEER 454
Query: 490 TSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
L+ ++E E+ +Q R + R R R
Sbjct: 455 RDWLK-REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR---RE 510
Query: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
+R++R R +R RS RR + E +K + +R +E+ERR
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR-----LEQERREQ 565
Query: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
R RE+ R + R R + R++ + +QR + E +EQ K+E
Sbjct: 566 RL-KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 670 SRSIDKDR--KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSI 727
+ + K +++E R+Q R+E+Q+R E+ K +++RL+++ + E R
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 728 SVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS 787
+ + +R+ K K + + +S S +E + ++ + R +S
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 788 QRSGKKASRKHKSK 801
+ ++ R H+ +
Sbjct: 745 ELQWQEEERAHRQQ 758
Score = 93.6 bits (231), Expect = 7e-19
Identities = 126/627 (20%), Positives = 246/627 (39%), Gaps = 75/627 (11%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
Q +R RDRQ +++EP Q KR+ + EG E + EKQ++LE+
Sbjct: 115 QEEDQRRFEPRDRQ-------LEEEPGQRRRQKRQEQERELAEGEE--QSEKQERLEQRD 165
Query: 256 MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPV 315
+++ +L ++ ++ E E Q K EE D E + ++ R
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 316 PQEEHSDPE----MTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAK 371
Q++ + + EEEKE++ E +L +E++ + P +
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKR--------ETVLRKEEEKLQ----------EEEPQR 267
Query: 372 QLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE- 430
Q L L + ++ R +R E ++R+KQE R++
Sbjct: 268 QRELQEEEEQLRKL---------ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 431 ---KEQQLLHDKQMEEEKQQTERVTKEMNEF-IHKEQNSLSLLEAREADGDVVNEKKRTP 486
+EQQ ++Q E +QQ R +E E + +EQ E RE E++R
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEE----ERREQQLRREQEEERRE 374
Query: 487 NETTSVLEPKKEHK-EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
+ + ++E + +E+Q R + R
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 546 SSRSSSPKRK---KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSI 602
+ +R+ KR R +K R R K + R + + RR +
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ---EEERRERWLKL 491
Query: 603 ERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
E E RR + RE++ R + +RR R R +R + QR + + E +E
Sbjct: 492 EEEERREQQERREQQLRREQE-ERREQRLKRQEEEERLQ---QRLRSEQQLRREQEERRE 547
Query: 663 QERKKERSRSIDKDRK----KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Q K+E + ++++R+ K+++E R+Q ++E+++R++ RLKR++E E
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ----------RLKREQE-E 596
Query: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
R R V+ + + R++ + + ++ E ++ ++ +
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 779 SRSRSVEKSQRSGKKASRKHKSKSRSR 805
R + E+ +R ++ R+H+ + R +
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQ 683
Score = 89.7 bits (221), Expect = 9e-18
Identities = 108/572 (18%), Positives = 234/572 (40%), Gaps = 95/572 (16%)
Query: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
E L + EREK+++ E ER +++ +L ++E++ + + RL +R + +EEE
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER--EKRRLQERERQYREEEELQQ 1058
Query: 298 ENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYV 357
E + + TR + ++ + E+ +EE++ LL E
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQ---------LLRE------------- 1096
Query: 358 AKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRH 417
+ ++ + +Q + L ++E E +EL
Sbjct: 1097 --EPEKRRRQERERQCREEEEL----------------QQEEEQLLREEREKRRRQELER 1138
Query: 418 RIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGD 477
+ R+++E +++E+QLL ++ + +Q+ ER +E E +E+ L RE
Sbjct: 1139 QYREEEEV---QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL-----REEQEK 1190
Query: 478 VVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS 537
E++R E + K++ + +++ RS + R + Y
Sbjct: 1191 RRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV--------YC 1242
Query: 538 SSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRS 597
+ + S R ++ + + ++ R R RR R + RDR
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR--------RWQQRDRHFP 1294
Query: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
+ERE ++ +RR R +++ R R R R++ D + +
Sbjct: 1295 EEEQLEREEQK-----EAKRRDRKSQEEKQLLREEREEKRRRQETDRK---------FRE 1340
Query: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRK-----EKQKREEKDFKFSSQDDRLK 712
E QER+++ R ++DRK +++E ++ RK ++ +R+E++ KF ++ +L+
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 713 -RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEK 771
++RE + R + R + +Q S++ +D K R E +E+
Sbjct: 1401 CQEREQQLRQDRD-----RKFREEEQQLSRQE--RDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 772 KAKKPKHSRSRSVEK--SQRSGKKASRKHKSK 801
+ ++ +H + R E+ +R ++ R+ + +
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Score = 88.6 bits (218), Expect = 2e-17
Identities = 116/642 (18%), Positives = 253/642 (39%), Gaps = 67/642 (10%)
Query: 198 RRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME 257
+RE+ R + ++QE + +KR R+ L K E +++++ ++ R E
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 258 QQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ 317
QQ + + +++ E+ RL QR K + +EE + E E R S +P+
Sbjct: 651 QQERREQRLKREEEEE-------RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Query: 318 EE--------------HSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
+ +S P E ++ Q K E L +EE AHR
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQE-EKRRRRESELQWQEEE------RAHR 756
Query: 364 KATKAPAKQ---LAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTD------DEE 414
+ + ++ + S G L + ER R E + +EE
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 415 LRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA 474
R RQ++E +EKE Q L +++ + +++ +++ +E + ++ S + R+
Sbjct: 817 KEQRRRQRRE----REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 475 DG--DVVNEKKRTPN--------------ETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
+ E+KR + E + E ++E + +E++ R R
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
+ R + ++K+ P + R+ R + Y
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 579 RIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
+++ ++ +R + R ER+ R+ +E + R++R + + R+
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Query: 639 RRKIDDQRGNLSGNSH--KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
++ + L G + + E + Q RK+E + ++ +++ E+ R Q++ E+Q
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER--ERQC 1110
Query: 697 REEKDFKFSSQ----DDRLKRKR-ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
REE++ + + ++R KR+R E ER + + + R++ +K ++ ++
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE-EEQLLREEPEKRRRQELERQ 1169
Query: 752 SGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKK 793
+ + E +++K ++ + + R E+ QR +K
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Score = 84.0 bits (206), Expect = 5e-16
Identities = 120/645 (18%), Positives = 255/645 (39%), Gaps = 112/645 (17%)
Query: 241 EKMEREKQKKLEKERMEQQRSQLSKKEK---KATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
E+ E ++K E+ER EQ+ + ++ + K E+ E + R Q+ K D +EE +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 298 ----ENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEE 353
E E + QEE + + +E+E + L + L +E L EE
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER---LQQRLRSEQQLRREQEE 544
Query: 354 IYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDE 413
+ + K+L Q L + E+ +R + ++E
Sbjct: 545 ------RREQLLKREEEKRLEQERREQRL--------------KREQEERRDQLLKREEE 584
Query: 414 ELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEARE 473
+ R++++QE R E+ + +++E+E+++ +R+ +E E E+ LL++ E
Sbjct: 585 RRQQRLKREQEE--RLEQRLKREEVERLEQEERREQRLKREEPE----EERRQQLLKSEE 638
Query: 474 ADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS------SGSSSSNSRTSST 527
+ + +R E ++E +E+ +Q R + +R
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS--------RSYSRR 579
S S +R S S P++++ R + K RR S R++ ++
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Query: 580 IKIESNR--------------------ARVKIRDRRRSNRNSIERERRRNR----SPSRE 615
+ E R AR +R++R + ER++R R +E
Sbjct: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKE 818
Query: 616 RRRSRSRSRDR------------RTNRAS--------------RSRSRDRRKIDDQRGNL 649
+RR + R R++ R RA R RS+++R+ R L
Sbjct: 819 QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878
Query: 650 SGNSHKHKGEA-----------KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
+ + KEQ+ +E + ++ ++K + +E+E+ R+E+Q ++
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 699 EKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG 758
E++ + ++ +R++E ER + + + K + + K+ + KK+ +
Sbjct: 939 EEEQLLREEREK-RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 759 RSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
+ + +EK+ ++ + R ++ Q+ ++ R+ + K R
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Score = 83.6 bits (205), Expect = 7e-16
Identities = 108/583 (18%), Positives = 235/583 (40%), Gaps = 61/583 (10%)
Query: 194 PPQNRRERPSSFRDRQ-RSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK-L 251
P + +RER +RQ R LP ++E Q +RR ++ EREK+ + L
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQ----RRR----------QRREREKELQFL 834
Query: 252 EKERMEQQRS---QLSKKEKKATEDAEG--GDGPRLPQRSKFDSDEEEEDTENVEAASSG 306
E+E Q+R QL ++E ED E R Q+ ++ +EE + + A
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 307 --KVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRK 364
+ R + QEE + + E EK + + E L +E++ ++ R+
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQ-ERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 365 ATKAPA----KQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR-- 418
+ K+L Q G+ ++R + E ++EEL+
Sbjct: 954 QERERQYRKDKKLQQKEEQLL------------GEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 419 --IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
+R+++E R+E E+Q ++++E++Q R +E +E+ E ++ +
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
++ E++ T + +KE + ++++ + R +
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE- 1120
Query: 537 SSSSGSSRTSSRSSSPKRKKRHSRS----------RSPTIKARRSRSRSYSRRIKIESNR 586
R R +R+ R P + R+ R Y +++
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646
++ +R+ + R ER+ R R++R+ R R D+R++ + + D +
Sbjct: 1181 EQL-LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
G ++ + ++ + + +S+ + + +ER+REQ++R+ +Q+ ++ F
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR--DRHF---P 1294
Query: 707 QDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
++++L+R+ + E S K + + R++ ++ D K
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Score = 74.3 bits (181), Expect = 4e-13
Identities = 101/539 (18%), Positives = 230/539 (42%), Gaps = 46/539 (8%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
Q R ++ RDR+ ++E Q+ +R + + + ERE++ E+++
Sbjct: 1402 QEREQQLRQDRDRK-------FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 256 MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPV 315
+ Q+R + ++E++ ++ E R + KF +E++ + + + RS P
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP- 1513
Query: 316 PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQ 375
+ + EEE++ + L E E +D RK + +QL Q
Sbjct: 1514 ------ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE--EQLRQ 1565
Query: 376 SSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQL 435
L+ + + + R ++ + + D+++LR + Q+Q R+E++++
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFME-DEQQLRRQEGQQQ---LRQERDRKF 1621
Query: 436 LHDKQM--EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
D+Q+ E E+QQ R ++ +F+ +E L +E + + +++ R E +L
Sbjct: 1622 REDEQLLQEREEQQLHRQERD-RKFLEEEPQ----LRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPK 553
+ + E ++ +Q R R R + R +
Sbjct: 1677 Q-EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ------------EEQQLRRQELER 1723
Query: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
+ + + R T + + R Y + ++ E R + + RR R+ RE + R
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-E 1782
Query: 614 RERRRSRSRSRDRRTNRASRSRS-RDRRKIDDQR--GNLSGNSHKHKGEAKEQERKKERS 670
RE ++ RS+ DR+ + R R+ +++ Q+ G + + E +EQ ++ER
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 671 RSIDKDRK--KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSI 727
R + + ++K R EQ+ +E++++ ++ + +++ ++R+++ E+ + G I
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEI 1901
Score = 73.9 bits (180), Expect = 5e-13
Identities = 118/631 (18%), Positives = 247/631 (39%), Gaps = 82/631 (12%)
Query: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKAT-EDAEGGDGPRLPQRSKFDSDEEEED 296
E L + EREK+++ E ER ++ ++ ++E++ E+ E L ++ + + + ++E+
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEE--KEYQMMLLTKMLLTEILLDVTDEEI 354
+ + + +EE + ++ E Q L E V D ++
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
Query: 355 YYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEE 414
Y ++ + + + QL + L L LG D E ER +EE
Sbjct: 1241 YCKGRE-NEQFRQLEDSQLRDRQSQQDLQHL--LGEQQERDREQERRRWQQRDRHFPEEE 1297
Query: 415 LRHRIRQKQ--EAFWRKEKEQQLLHDKQMEEEK-QQTERVTKEMNEFIHKEQNSLSLLEA 471
R QK+ + ++E+QLL +++ E+ + Q+T+R +E + + + + L
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP--LRR 1355
Query: 472 READGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTV 531
+E D E+ R + LE ++ + +E++ + +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRS---PTIKARRSRSRSYSRRIKIESNRAR 588
S R ++ +R R R + R+ R R + ++ R
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 589 VKI----RDR---------RRSNRNSIERERR-RNRSPSRE------------------- 615
++ RDR RR R+ RE+ R++ P R+
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 616 -----RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK-----HKGEAKEQER 665
RR+ R + R + +R R + R++ ++Q+ + K K +EQER
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 666 K----------KERSRSIDKDRKKKDKEREREQDKRKEKQ-KREEKDFKFSSQDDRLKRK 714
K +E + + ++R +K +E E+ +R+E+Q R+E+D KF ++ +L+R+
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
++ +RHD +D K + + R + +E++ +
Sbjct: 1656 EREQQ------------LRHD--RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Query: 775 KPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
+ + R E+ Q ++ RK + + + R
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Score = 60.5 bits (145), Expect = 6e-09
Identities = 114/617 (18%), Positives = 248/617 (40%), Gaps = 65/617 (10%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGL-----EKMEREKQKK 250
Q R+ S RDRQ + E + D + R W + E++ERE+QK+
Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR--RWQQRDRHFPEEEQLEREEQKE 1306
Query: 251 LEK-ERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEE---EEDTENVEAASSG 306
++ +R Q+ QL ++E++ + D KF +E+ E + + +
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETD-------RKFREEEQLLQEREEQPLRRQERD 1359
Query: 307 KVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKAT 366
+ R QE+ + EEE+ + + L E E + +D RK
Sbjct: 1360 RKFREEELRHQEQGR--KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF- 1416
Query: 367 KAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDE--ELRHRIRQKQE 424
+ +QL++ + + + R +R + + + + + RHR +++E
Sbjct: 1417 REEEQQLSRQERDRK---------FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 425 AFWRKEKEQQLLH---DKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNE 481
++ +EQQL D++ EE+QQ R ++ +EQ L ++E + + E
Sbjct: 1468 QLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK---FREQE----LRSQEPERKFLEE 1520
Query: 482 KKRTPNETTS--VLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSS 539
+++ + L+ +++ + +E+ + R R +S
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 540 SGSSRTSSRSSSPKRK----KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRR 595
R +RK ++ R + + R+ R R + ++ R ++ R+
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH-RQ 1639
Query: 596 RSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK 655
+R +E E + R +ER + RDR+ R + ++ ++Q+ K
Sbjct: 1640 ERDRKFLEEEPQLRR---QEREQQLRHDRDRKF----REEEQLLQEGEEQQLRRQERDRK 1692
Query: 656 HKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
+ E ++Q R++ER R ++ ++ + +E E+ R+E+Q R+E + + + +R ++
Sbjct: 1693 FR-EEEQQLRRQERERKFLQEEQQL-RRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Query: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK 775
E E+ ++ RQ+ + ++ + + S ES +E++ +
Sbjct: 1751 EEEQLRPEREEQQLR------RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 776 PKHSRSRSVEKSQRSGK 792
+ + + QR GK
Sbjct: 1805 -QEREEQQLRPQQRDGK 1820
Score = 54.7 bits (130), Expect = 3e-07
Identities = 47/248 (18%), Positives = 99/248 (39%), Gaps = 20/248 (8%)
Query: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRA 631
R RR + + + RRR R ERE S ++ R R R RR
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 632 SRSR----SRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
R R R+ R+ ++++ + +EQ R++E K R++K ++R
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 688 QDK------RKEKQKRE----EKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSR 737
QD+ KE +KRE +++ K ++ + +R+ + E R K+ R + R
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR------KLERQELR 287
Query: 738 QDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
++ ++ + + + E +E++ ++ + + + Q ++ R+
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 798 HKSKSRSR 805
+ R +
Sbjct: 348 EQQLRREQ 355
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/209 (19%), Positives = 88/209 (42%), Gaps = 20/209 (9%)
Query: 595 RRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
R + S+ ++RR+ E + R RDR+ R R +R+ + +R G
Sbjct: 102 RCDGKESLLQDRRQ------EEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELAEGEEQ 154
Query: 655 KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK 714
K E EQ ++ R + + R++ +ERE+ + +E+Q + K + D + +
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEW---QEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
R R G R + +Q ++ + ++ + R E+ +E+K +
Sbjct: 212 RRELLELRRKG-------REEKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQ 261
Query: 775 KPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
+ + R R +++ + +K R+ + R
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRER 290
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 90.5 bits (223), Expect = 6e-18
Identities = 93/288 (32%), Positives = 138/288 (47%), Gaps = 17/288 (5%)
Query: 462 EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQG--RSRSGSSSSGSSS 519
E+ S S E ++ D ++ + K T ++ K KEK++ RSRS S S
Sbjct: 1777 ERASESSSEEKD-DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK 1835
Query: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
S RTS + S S S S S+T SRS S +R++R SRSRS K+R RS S +R
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRS-RRRRRSSRSRS---KSRGRRSVSKEKR 1891
Query: 580 IKIESNRARVKIRDRRRSN-RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
+ +R++ + R R+RS+ R++ + R R+R+PSR R RS + SR RR+ R RS
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRS-- 1948
Query: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
I R + + S + + ++ RSR+ R+ + R R+ + +
Sbjct: 1949 -FSISPSRRSRT-PSRRSRTPSRRSRTPSRRSRT--PSRRSRTPSRRSRTPSRRRRSRSV 2004
Query: 699 EKDFKFSSQDDRLKRKRES-ERTFSRSGSISVKIIRHDSRQDSKKSTT 745
+ FS RL+R R R FSRS I K R R S K T
Sbjct: 2005 VRRRSFSISPVRLRRSRTPLRRRFSRS-PIRRKRSRSSERGRSPKRLT 2051
Score = 90.1 bits (222), Expect = 7e-18
Identities = 83/316 (26%), Positives = 134/316 (42%), Gaps = 31/316 (9%)
Query: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSS---------RSS 550
K+ E+ R+G +S R S +S V SS +S SS + +
Sbjct: 1740 KDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDT 1799
Query: 551 SPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR 610
K KK +R + K R S RS S+R K +++R + + R R R+R+
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESR-------SRARKRSS 1852
Query: 611 SPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERS 670
R ++RSRSR RR R+SRSRS+ R R ++S K + + + R+++R
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSR-----GRRSVSKEKRKRSPKHRSKSRERKRK 1907
Query: 671 RSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVK 730
RS +D +K + R R +R + R R R+FS S S +
Sbjct: 1908 RSSSRDNRKTVRARSRTPSRRSRSHTPSRR---------RRSRSVGRRRSFSISPSRRSR 1958
Query: 731 IIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ-R 789
SR S++S T + + S S S S S+ ++++ RS S+ + R
Sbjct: 1959 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLR 2018
Query: 790 SGKKASRKHKSKSRSR 805
+ R+ S+S R
Sbjct: 2019 RSRTPLRRRFSRSPIR 2034
Score = 87.8 bits (216), Expect = 4e-17
Identities = 90/306 (29%), Positives = 131/306 (42%), Gaps = 41/306 (13%)
Query: 472 READGDVVNEKKRTPNETTSVLEPKKEH----KEKEKQGRSRSGSSSSGSSSSNSRTSST 527
R A VV+ +E++S E K ++ K K+ +S+ + R SS
Sbjct: 1765 RSAASPVVSSMPERASESSS--EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 528 SSTVSSSSYSSSSGSSRTS-SRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586
S S S RTS SRS + KR + RS T RSRSRS RR S+R
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT----RSRSRSRRRR---RSSR 1875
Query: 587 ARVKIRDRRRSNRNSIERERR----RNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI 642
+R K R RR S+ +E+R ++RS SRER+R RS SRD R +RSR+ RR
Sbjct: 1876 SRSKSRGRR-----SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR-- 1928
Query: 643 DDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRK-----EKQKR 697
SH + + + RS SI R+ + R R+ + +
Sbjct: 1929 --------SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1980
Query: 698 EEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIR-HDSRQDSKK--STTKDSKKHSGS 754
+ + S+ R +R R+ R S S+ +R SR ++ S + +K S S
Sbjct: 1981 PSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Query: 755 DSSGRS 760
GRS
Sbjct: 2041 SERGRS 2046
Score = 72.4 bits (176), Expect = 2e-12
Identities = 86/294 (29%), Positives = 122/294 (41%), Gaps = 52/294 (17%)
Query: 443 EEKQQTERVTK--EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHK 500
EEK E K + +E K +N + ++ D + + KR+ + E K +
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS-----EHKSRKR 1839
Query: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSR 560
E + R+R SS S S S +R+ S S SS S S R S KR +H R
Sbjct: 1840 TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH-R 1898
Query: 561 SRSPTIKARRSRSRSYSRRIKIESN----RARVKIRDRRRSNRNSIERER-------RRN 609
S+S K +RS SR + ++ S R+R RRR +R S+ R R RR+
Sbjct: 1899 SKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR-SVGRRRSFSISPSRRS 1957
Query: 610 RSPSRERR----RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
R+PSR R RSR+ SR RT + RSR+ RR R + +
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSR------------RRRSRSV 2004
Query: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
+ RS SI R ++ + R +FS R KR R SER
Sbjct: 2005 VRRRSFSISPVRLRRSRTPLRR---------------RFSRSPIRRKRSRSSER 2043
Score = 69.3 bits (168), Expect = 1e-11
Identities = 69/256 (26%), Positives = 114/256 (44%), Gaps = 24/256 (9%)
Query: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMN 456
+++ D+G E D LR R ++ + + + K + E + +R +K +
Sbjct: 1805 KNKNRDKG-EKEKKRDSSLRSRSKRSKSSEHKSRK-------RTSESRSRARKRSSKSKS 1856
Query: 457 EFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSG 516
S S R + + +R+ ++ PK K +E++ + S +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916
Query: 517 SSSSNSRT---SSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR--RS 571
+ + SRT S S T S S S G R+ S S S + + RSR+P+ ++R
Sbjct: 1917 TVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR 1976
Query: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERER--------RRNRSPSRERRRSRSRS 623
RSR+ SRR + S R+R RRR +R+ + R RR+R+P R RR SRS
Sbjct: 1977 RSRTPSRRSRTPSRRSRTP--SRRRRSRSVVRRRSFSISPVRLRRSRTPLR-RRFSRSPI 2033
Query: 624 RDRRTNRASRSRSRDR 639
R +R+ + R RS R
Sbjct: 2034 RRKRSRSSERGRSPKR 2049
Score = 55.8 bits (133), Expect = 2e-07
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 47/293 (16%)
Query: 351 DEEIYYVAKDAHRKATKAP-----AKQLAQSSALASLTGLGGLGGYGSGDSEDE---RSD 402
D EI+ KD H K+ K K+ + S+L S + + S E R+
Sbjct: 1789 DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRAR 1848
Query: 403 RGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE 462
+ S S + + R R R ++ R+ + + K++ +R K ++ ++
Sbjct: 1849 KRSSKSKSHRSQTRSRSRSRRR---RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERK 1905
Query: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKE----------KQGRSRSGS 512
+ S + R+ V + RTP+ + P + + + RSR+ S
Sbjct: 1906 RKRSSSRDNRKT----VRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR 572
S + S SRT S S S + S SRT SR R RS ++ RRS
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-----------RRRSRSVVRRRSF 2010
Query: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRD 625
S S + R+R + RRR +R+ I RR RS S ER RS R D
Sbjct: 2011 SIS-----PVRLRRSRTPL--RRRFSRSPI----RRKRSRSSERGRSPKRLTD 2052
Score = 37.7 bits (86), Expect = 0.043
Identities = 20/83 (24%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 640 RKIDDQRGNLSGNSHKHKGEAKEQERKKE----RSRSIDKDRKKKDKEREREQDKRKEKQ 695
+KI++ + ++K + KE RK ++ D+ KK K+ ++ ++K+K+K+
Sbjct: 63 QKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKK 122
Query: 696 KREEKDFKFSSQDDRLKRKRESE 718
K +EK +K ++ K K +
Sbjct: 123 KEKEKKYKRQPEESESKTKSHDD 145
Score = 32.7 bits (73), Expect = 1.4
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 242 KMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTE-NV 300
K + K+KK +KE+ ++ + Q + E K +G KFDS+ E
Sbjct: 112 KKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPT 171
Query: 301 EAASSGKVTRSPS-----PVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEI 354
A + SP+ PV E S+P + E K ++ T ++ + +++ +
Sbjct: 172 RAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSV 230
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 90.5 bits (223), Expect = 6e-18
Identities = 93/288 (32%), Positives = 138/288 (47%), Gaps = 17/288 (5%)
Query: 462 EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQG--RSRSGSSSSGSSS 519
E+ S S E ++ D ++ + K T ++ K KEK++ RSRS S S
Sbjct: 1777 ERASESSSEEKD-DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK 1835
Query: 520 SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRR 579
S RTS + S S S S S+T SRS S +R++R SRSRS K+R RS S +R
Sbjct: 1836 SRKRTSESRSRARKRSSKSKSHRSQTRSRSRS-RRRRRSSRSRS---KSRGRRSVSKEKR 1891
Query: 580 IKIESNRARVKIRDRRRSN-RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
+ +R++ + R R+RS+ R++ + R R+R+PSR R RS + SR RR+ R RS
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRS-- 1948
Query: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
I R + + S + + ++ RSR+ R+ + R R+ + +
Sbjct: 1949 -FSISPSRRSRT-PSRRSRTPSRRSRTPSRRSRT--PSRRSRTPSRRSRTPSRRRRSRSV 2004
Query: 699 EKDFKFSSQDDRLKRKRES-ERTFSRSGSISVKIIRHDSRQDSKKSTT 745
+ FS RL+R R R FSRS I K R R S K T
Sbjct: 2005 VRRRSFSISPVRLRRSRTPLRRRFSRS-PIRRKRSRSSERGRSPKRLT 2051
Score = 90.1 bits (222), Expect = 7e-18
Identities = 83/316 (26%), Positives = 134/316 (42%), Gaps = 31/316 (9%)
Query: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSS---------RSS 550
K+ E+ R+G +S R S +S V SS +S SS + +
Sbjct: 1740 KDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDT 1799
Query: 551 SPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNR 610
K KK +R + K R S RS S+R K +++R + + R R R+R+
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESR-------SRARKRSS 1852
Query: 611 SPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERS 670
R ++RSRSR RR R+SRSRS+ R R ++S K + + + R+++R
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSR-----GRRSVSKEKRKRSPKHRSKSRERKRK 1907
Query: 671 RSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVK 730
RS +D +K + R R +R + R R R+FS S S +
Sbjct: 1908 RSSSRDNRKTVRARSRTPSRRSRSHTPSRR---------RRSRSVGRRRSFSISPSRRSR 1958
Query: 731 IIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ-R 789
SR S++S T + + S S S S S+ ++++ RS S+ + R
Sbjct: 1959 TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLR 2018
Query: 790 SGKKASRKHKSKSRSR 805
+ R+ S+S R
Sbjct: 2019 RSRTPLRRRFSRSPIR 2034
Score = 87.8 bits (216), Expect = 4e-17
Identities = 90/306 (29%), Positives = 131/306 (42%), Gaps = 41/306 (13%)
Query: 472 READGDVVNEKKRTPNETTSVLEPKKEH----KEKEKQGRSRSGSSSSGSSSSNSRTSST 527
R A VV+ +E++S E K ++ K K+ +S+ + R SS
Sbjct: 1765 RSAASPVVSSMPERASESSS--EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 528 SSTVSSSSYSSSSGSSRTS-SRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586
S S S RTS SRS + KR + RS T RSRSRS RR S+R
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT----RSRSRSRRRR---RSSR 1875
Query: 587 ARVKIRDRRRSNRNSIERERR----RNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI 642
+R K R RR S+ +E+R ++RS SRER+R RS SRD R +RSR+ RR
Sbjct: 1876 SRSKSRGRR-----SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR-- 1928
Query: 643 DDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRK-----EKQKR 697
SH + + + RS SI R+ + R R+ + +
Sbjct: 1929 --------SRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1980
Query: 698 EEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIR-HDSRQDSKK--STTKDSKKHSGS 754
+ + S+ R +R R+ R S S+ +R SR ++ S + +K S S
Sbjct: 1981 PSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Query: 755 DSSGRS 760
GRS
Sbjct: 2041 SERGRS 2046
Score = 72.4 bits (176), Expect = 2e-12
Identities = 86/294 (29%), Positives = 122/294 (41%), Gaps = 52/294 (17%)
Query: 443 EEKQQTERVTK--EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHK 500
EEK E K + +E K +N + ++ D + + KR+ + E K +
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS-----EHKSRKR 1839
Query: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSR 560
E + R+R SS S S S +R+ S S SS S S R S KR +H R
Sbjct: 1840 TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKH-R 1898
Query: 561 SRSPTIKARRSRSRSYSRRIKIESN----RARVKIRDRRRSNRNSIERER-------RRN 609
S+S K +RS SR + ++ S R+R RRR +R S+ R R RR+
Sbjct: 1899 SKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR-SVGRRRSFSISPSRRS 1957
Query: 610 RSPSRERR----RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
R+PSR R RSR+ SR RT + RSR+ RR R + +
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTP-SRRSRTPSRRSRTPSR------------RRRSRSV 2004
Query: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
+ RS SI R ++ + R +FS R KR R SER
Sbjct: 2005 VRRRSFSISPVRLRRSRTPLRR---------------RFSRSPIRRKRSRSSER 2043
Score = 69.3 bits (168), Expect = 1e-11
Identities = 69/256 (26%), Positives = 114/256 (44%), Gaps = 24/256 (9%)
Query: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMN 456
+++ D+G E D LR R ++ + + + K + E + +R +K +
Sbjct: 1805 KNKNRDKG-EKEKKRDSSLRSRSKRSKSSEHKSRK-------RTSESRSRARKRSSKSKS 1856
Query: 457 EFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSG 516
S S R + + +R+ ++ PK K +E++ + S +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916
Query: 517 SSSSNSRT---SSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR--RS 571
+ + SRT S S T S S S G R+ S S S + + RSR+P+ ++R
Sbjct: 1917 TVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR 1976
Query: 572 RSRSYSRRIKIESNRARVKIRDRRRSNRNSIERER--------RRNRSPSRERRRSRSRS 623
RSR+ SRR + S R+R RRR +R+ + R RR+R+P R RR SRS
Sbjct: 1977 RSRTPSRRSRTPSRRSRTP--SRRRRSRSVVRRRSFSISPVRLRRSRTPLR-RRFSRSPI 2033
Query: 624 RDRRTNRASRSRSRDR 639
R +R+ + R RS R
Sbjct: 2034 RRKRSRSSERGRSPKR 2049
Score = 55.8 bits (133), Expect = 2e-07
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 47/293 (16%)
Query: 351 DEEIYYVAKDAHRKATKAP-----AKQLAQSSALASLTGLGGLGGYGSGDSEDE---RSD 402
D EI+ KD H K+ K K+ + S+L S + + S E R+
Sbjct: 1789 DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRAR 1848
Query: 403 RGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE 462
+ S S + + R R R ++ R+ + + K++ +R K ++ ++
Sbjct: 1849 KRSSKSKSHRSQTRSRSRSRRR---RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERK 1905
Query: 463 QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKE----------KQGRSRSGS 512
+ S + R+ V + RTP+ + P + + + RSR+ S
Sbjct: 1906 RKRSSSRDNRKT----VRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR 572
S + S SRT S S S + S SRT SR R RS ++ RRS
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-----------RRRSRSVVRRRSF 2010
Query: 573 SRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRD 625
S S + R+R + RRR +R+ I RR RS S ER RS R D
Sbjct: 2011 SIS-----PVRLRRSRTPL--RRRFSRSPI----RRKRSRSSERGRSPKRLTD 2052
Score = 37.7 bits (86), Expect = 0.043
Identities = 20/83 (24%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 640 RKIDDQRGNLSGNSHKHKGEAKEQERKKE----RSRSIDKDRKKKDKEREREQDKRKEKQ 695
+KI++ + ++K + KE RK ++ D+ KK K+ ++ ++K+K+K+
Sbjct: 63 QKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKK 122
Query: 696 KREEKDFKFSSQDDRLKRKRESE 718
K +EK +K ++ K K +
Sbjct: 123 KEKEKKYKRQPEESESKTKSHDD 145
Score = 32.7 bits (73), Expect = 1.4
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 242 KMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTE-NV 300
K + K+KK +KE+ ++ + Q + E K +G KFDS+ E
Sbjct: 112 KKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPT 171
Query: 301 EAASSGKVTRSPS-----PVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEI 354
A + SP+ PV E S+P + E K ++ T ++ + +++ +
Sbjct: 172 RAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSV 230
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/283 (33%), Positives = 129/283 (45%), Gaps = 32/283 (11%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
+NRA + R R + RR +RSP R RSRSRS RR+
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
Query: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEES 175
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 176 PLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
Query: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
S S S S++P S AK S S++ S +RSG
Sbjct: 233 PPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
Score = 55.5 bits (132), Expect = 2e-07
Identities = 88/398 (22%), Positives = 160/398 (40%), Gaps = 52/398 (13%)
Query: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIRQKQEAFWRKEKEQQLLH 437
G + ++ED R R S +D T++E L+++ + + + ++ +
Sbjct: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
Query: 438 DKQMEE----EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
DK E E+ T TK+ ++ K +++ + ++ V +EK + + + L
Sbjct: 457 DKHKETGYVVERPST---TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
Query: 494 EPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSRS 549
+ +EK ++ R +S S + + S+ +S R +S
Sbjct: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
Query: 550 SSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRSN 598
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 574 VHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSY 633
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
+ + E R +SP RR S S R+ D R ++R N KG
Sbjct: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRK----------DTRLAGEERVFKEENQ---KG 680
Query: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLKR 713
+ K + + ID RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 681 DKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKH 740
Query: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
KRE + + S S S S ++SKK ++ K H
Sbjct: 741 KREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Score = 53.1 bits (126), Expect = 1e-06
Identities = 137/713 (19%), Positives = 261/713 (36%), Gaps = 116/713 (16%)
Query: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 219 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 277
Query: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
++ +P QN P +RSP Q P+
Sbjct: 278 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 310
Query: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 311 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 365
Query: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 366 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 417
Query: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
K T + +E + Y +K D R+ K+ S T
Sbjct: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTK---- 473
Query: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 474 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 530
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 531 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 586
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
+ H + + +S S S S S + T+S S + S+
Sbjct: 587 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHST 642
Query: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR 607
R SP+ +R S P+ + +R R K E+ + K+R R+ I+ R+
Sbjct: 643 RQKSPEIHRRIDIS--PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRK 700
Query: 608 RNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK 667
ER + R S+ R +R SR + + + + + + HK + +
Sbjct: 701 -------ERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKRE-QDHSLSSSS 752
Query: 668 ERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ------DDRLKRKRESERTF 721
S S R++K+ ++ERE++ + + +E F S+ DDR + +
Sbjct: 753 SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDR----DDGVDYW 808
Query: 722 SRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG--RSSSESPGSSKEKK 772
++ G R R + KKS + H G E+ +++EKK
Sbjct: 809 AKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKK 861
Score = 46.6 bits (109), Expect = 9e-05
Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDR------RTNRASRSRSRDRRKIDDQRGNLSGN 652
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + N
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
Query: 653 -------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
++ +G Q R + R +R + R K S
Sbjct: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 119
Query: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
SQ R + +R + S S S + SK+ + S++ + G ESP
Sbjct: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEESP 176
Query: 766 GSSKEKKAKKP--KHSRSRSVEKSQRS 790
SK ++ K +H S S+++ +S
Sbjct: 177 LKSKSQEEPKDTFEHDPSESIDEFNKS 203
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
Query: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
R+ R + R G V RH SR S K+ + +
Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
Query: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
Score = 45.1 bits (105), Expect = 3e-04
Identities = 151/738 (20%), Positives = 259/738 (35%), Gaps = 137/738 (18%)
Query: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
DY++ A P G G Y+Q G G P NRR S R R RS
Sbjct: 58 DYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 110
Query: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 111 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
Query: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
Query: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
+ + ML T T + + + +
Sbjct: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
Query: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSE------------DERS----- 401
H + ++PAK +A +A + GD E DE S
Sbjct: 289 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLL 348
Query: 402 DRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEK------QQTERVTKEM 455
DRG+ + D + + + + + E W ++ DK+ ++K TE T++
Sbjct: 349 DRGN-TRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEE-TEDY 406
Query: 456 NEFIH-----------------------KEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
+F K ++ +SL RE+DG EK ET V
Sbjct: 407 RQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDG-FREEKNDKHKETGYV 465
Query: 493 LE----PKKEHKEKEKQGRSRSGSSSSGSSSS-NSRTSSTSSTVSSSSYSSSSGSSRTSS 547
+E K +HKE++K + + S S S + + +++
Sbjct: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
Query: 548 RSSSPKRKKR-HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR--NSIER 604
R SP R K S S P +K + + +SNR +DR ++ +S+++
Sbjct: 526 REESPLRIKMIASDSHRPEVKLKMAPVPLD------DSNRPASLTKDRLLASTLVHSVKK 579
Query: 605 ER--RRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
E+ R + + S+S S + S + LS ++ +E
Sbjct: 580 EQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEE 639
Query: 663 QERKKE-----RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-----DRLK 712
+++ R I +KD E+ KE+ ++ +K + S D D +
Sbjct: 640 HSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRR 699
Query: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKS--TTKDSKKHS-----GSDSSGRSSSESP 765
++R ER S+ S + + K + KD KH SS +S SP
Sbjct: 700 KERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSP 759
Query: 766 GSSKEKKAKKPKHSRSRS 783
S +EK++KK + ++
Sbjct: 760 SSREEKESKKEREEEFKT 777
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 163 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 219
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
R S N R SP RS ++ A R SR R
Sbjct: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
Query: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
Query: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
Query: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 440 VSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
Score = 42.0 bits (97), Expect = 0.002
Identities = 97/464 (20%), Positives = 160/464 (34%), Gaps = 48/464 (10%)
Query: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
E E K K ++ R +E+K + E G P +K EE++++E +
Sbjct: 430 EEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK 489
Query: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
K T+SP V E+ D + K E + I +A D+HR
Sbjct: 490 ---KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
Query: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
K AP L S+ ASLT L + E+ R S T +
Sbjct: 543 PEVKLKMAPV-PLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
Query: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE---QNS 465
++H + K++ F + L ++ +K E T++ + IH+ S
Sbjct: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
Query: 466 LSLLEAREADGDVVNEKKRTPNE-----TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
+ R A + V +++ + ++ L +H+ KE RS+ S GS S
Sbjct: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE---RSKERGDSKGSRES 715
Query: 521 NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRI 580
+ Y S S+ KR++ HS S S + SR
Sbjct: 716 RGSRKQEKTPKDYKEYKSYKDDSK-------HKREQDHSLSSSSSASPSSPSSREEKESK 768
Query: 581 KIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640
K + + S + R R +R R R + R R R
Sbjct: 769 KEREEEFKTHHEMKEYSGFAGVSRPRGTFHD---DRDDGVDYWAKRGRGRGTFQRGRGRF 825
Query: 641 KIDDQRGNLSGNSHKHKGEA-KEQERKKERSRSIDKDRKKKDKE 683
+ N K++G+ E E + + KDR K++KE
Sbjct: 826 NFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582
S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
Query: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
Query: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
Query: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
Query: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
S S S S++P S AK S S++ S +RSG
Sbjct: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 18/170 (10%)
Query: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646
A + + +R S + + E R +SP RR S S R+ R + + R ++
Sbjct: 451 AAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN 506
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDF 702
KG+ K + + ID+ RK++ KER + R+ KQ++ KD+
Sbjct: 507 ---------QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDY 557
Query: 703 K-FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
K + S D K KRE + + S S S S ++SKK ++ K H
Sbjct: 558 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
Score = 50.4 bits (119), Expect = 6e-06
Identities = 115/578 (19%), Positives = 209/578 (36%), Gaps = 86/578 (14%)
Query: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
Query: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
Query: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
Query: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
+ + ML T T + + + +
Sbjct: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
Query: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
H + ++PAK +A +A + GD E ++ + +S L
Sbjct: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPP-----LHKN 345
Query: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
+ ++++ +R+E ++ K + + + E K + SL + R +
Sbjct: 346 LDAREKSTFREESPLRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 402
Query: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSS 533
V+ K+ E S+ + H + + +S S S S S + T++
Sbjct: 403 VHSVKKE-QEFRSIFD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE 457
Query: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR- 592
S + S+R SP+ +R S P+ + +R R K E+ + K+R
Sbjct: 458 RFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
Query: 593 ---------DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643
DRRR R+ + + +R S R++ ++ +D + ++ + S+ +R+ D
Sbjct: 516 DSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQD 574
Query: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681
R + S S +E+E KKER + K+
Sbjct: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
G + SH + +++ Q + RSRS + ++ + R R + + + + +D++
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
Query: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
+++R R+ R + R G V RH +S ++ K+ S
Sbjct: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
Query: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801
SS RS S S S + ++ + SRS S KS S ++ S++ ++K
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R +
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
Query: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
N ++ +G Q R + R +R + R K
Sbjct: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
Query: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
SSQ R + +R + S S S + SK+ + S++ + G E
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
Query: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790
SP SK ++ K +H S S+++ +S
Sbjct: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
Score = 45.8 bits (107), Expect = 2e-04
Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 19/226 (8%)
Query: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530
+RE+ G EK TP + K + K K +Q SRS SSS+ SS +SR S
Sbjct: 541 SRESSGSRKQEK--TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 598
Query: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590
+ + S + SR R R R R +R + +N
Sbjct: 599 EREEEFKTHHEMKEYSGFAGV-------SRPRGTFF---RIRGRGRARGVFAGTNTG--- 645
Query: 591 IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS 650
SN +R + P + + D R + R R + QRG
Sbjct: 646 ---PNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGR 702
Query: 651 GNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
N K G + + K + I +D ++ + E ++D+RKE+++
Sbjct: 703 FN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
Score = 45.1 bits (105), Expect = 3e-04
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%)
Query: 631 ASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
++R +S + R+ID L KH A E+ KE ++ DK + + + D
Sbjct: 470 STRQKSPEIHRRIDISPSTL----RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
+R++++ +E D K S + +++ ++ + + S + DSK +D
Sbjct: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD-- 574
Query: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
HS S SS S S SP S +EK++KK + ++
Sbjct: 575 -HSRSSSSSASPS-SPSSREEKESKKEREEEFKT 606
Score = 43.5 bits (101), Expect = 8e-04
Identities = 103/473 (21%), Positives = 160/473 (33%), Gaps = 63/473 (13%)
Query: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
Query: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
E ++EF S + A + R+P+ + + P +
Sbjct: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
Query: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-- 566
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
Query: 567 -KARRSRSRSYSRRIKIESNRARVKIRDRRRS-----NRNSIERERRRNRSPSR------ 614
A R SR S ++ K +S N ++ E+ R SP R
Sbjct: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
Query: 615 -----------------ERRRSRSRSRDR---RTNRASRSRSRDRRKIDD-----QRGNL 649
+ R S ++DR T S + ++ R I D Q
Sbjct: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
Query: 650 SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709
+ S + K++ +S ++ ++ ++ +QK E +
Sbjct: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
Query: 710 RLKRKRE---SERTFSRSGSISVKIIR-------HDSRQDSK-KSTTKDSKKHSGSDSSG 758
L++ ER F K +R HD + K +S + K S S
Sbjct: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
Query: 759 RSSSESPGSSKEKKAKK--PKHSR----SRSVEKSQRSGKKASRKHKSKSRSR 805
R ++P KE K+ K KH R SRS S +SR+ K + R
Sbjct: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600
Score = 34.3 bits (77), Expect = 0.47
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GRS+S S S + +++ SRSRS + +R ++ + S+SRSR
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
+S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+
Sbjct: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582
S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
Query: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
Query: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
Query: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
Query: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
S S S S++P S AK S S++ S +RSG
Sbjct: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
Score = 57.0 bits (136), Expect = 7e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 399 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 458
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 459 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 514
Query: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 515 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 574
Query: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 575 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 634
Query: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 635 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 681
Query: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 682 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 741
Query: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
KRE + + S S S S ++SKK ++ K H
Sbjct: 742 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 221 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
Query: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
++ +P QN P +RSP Q P+
Sbjct: 280 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 312
Query: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 313 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 367
Query: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 368 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 419
Query: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
K T + +E + Y +K D R+ K+ S T
Sbjct: 420 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 475
Query: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 476 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 532
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 533 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 588
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
+ H + + +S S S S S + T++ S + S+
Sbjct: 589 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 644
Query: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 645 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 702
Query: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 703 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 761
Query: 658 GEAKEQERKKERSRSIDKDRKKKD 681
+E+E KKER + K+
Sbjct: 762 SSREEKESKKEREEEFKTHHEMKE 785
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
G + SH + +++ Q + RSRS + ++ + R R + + + + +D++
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
Query: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754
+++R R+ R + R G V RH +S ++ K+ S
Sbjct: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
Query: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801
SS RS S S S + ++ + SRS S KS S ++ S++ ++K
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
Score = 47.4 bits (111), Expect = 5e-05
Identities = 105/507 (20%), Positives = 178/507 (35%), Gaps = 67/507 (13%)
Query: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 432 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 488
Query: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 489 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 544
Query: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
K AP L S+ ASLT L + E+ R S T +
Sbjct: 545 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 603
Query: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK------- 461
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 604 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
Query: 462 ---EQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
+ L+ E + + +KK + + + KE+ K+ GS S S
Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
Query: 519 SSNSRTSSTSSTVSS----SSYSSSSGSSRTSSRSSSP-----KRKKRHSRSRSPTIKAR 569
+T S S + SR+SS S+SP + +K + R K
Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
Query: 570 RSRSRSYSRRIKIESNRA---RVKIRDRRR------------SNRNSIERERRRNRSPSR 614
+ YS + R R++ R R R SN +R + P
Sbjct: 781 HEM-KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY 839
Query: 615 ERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSID 674
+ + D R + R R + QRG N K K K + ++
Sbjct: 840 TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVE 899
Query: 675 KDRKKKDKEREREQDKRKEKQKREEKD 701
D+E E ++ K+ +++EEK+
Sbjct: 900 ------DEEETMENNEEKKDRRKEEKE 920
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R +
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
Query: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
N ++ +G Q R + R +R + R K
Sbjct: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
Query: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
SSQ R + +R + S S S + SK+ + S++ + G E
Sbjct: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
Query: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790
SP SK ++ K +H S S+++ +S
Sbjct: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 165 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 222 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 270
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
R S N R SP RS ++ A R SR R
Sbjct: 271 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 326
Query: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 327 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 384
Query: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 385 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 441
Query: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 442 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 496
Score = 40.0 bits (92), Expect = 0.009
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
Query: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
E ++EF S + A + R+P+ + + P +
Sbjct: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
Query: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
Query: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
+ SR RS + +R E +R R RD+ S E
Sbjct: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 367
Query: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
+ R N S + + + R++ A + +S
Sbjct: 368 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 427
Query: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 428 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 487
Query: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 488 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 546
Query: 741 KK 742
K
Sbjct: 547 VK 548
Score = 39.7 bits (91), Expect = 0.011
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
Query: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
Query: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
Query: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
+ + ML T T + + + +
Sbjct: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
Query: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 291 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 348
Query: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 349 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 403
Query: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 404 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 463
Query: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 464 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 513
Query: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
N ++ E+ R SP R + R S ++DR
Sbjct: 514 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 573
Query: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 574 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 633
Query: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
++ ++ +QK E + L++ ER F K +R
Sbjct: 634 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 693
Query: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 694 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 753
Query: 786 KSQRSGKKASRKHKSKSRSR 805
S +SR+ K + R
Sbjct: 754 SSASPSSPSSREEKESKKER 773
Score = 34.3 bits (77), Expect = 0.47
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GRS+S S S + +++ SRSRS + +R ++ + S+SRSR
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
+S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+
Sbjct: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 88.6 bits (218), Expect = 2e-17
Identities = 89/412 (21%), Positives = 163/412 (39%), Gaps = 64/412 (15%)
Query: 456 NEFIHKE---QNSLSLLEAREADG---DVVNEKKRTPNETTSVLEPKKEHKE------KE 503
NEF HK+ +N+++ ++ G + ++ +T + +E + +
Sbjct: 1184 NEFHHKDPPPRNAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSRERSQCGVKAVNK 1243
Query: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS-----------SSP 552
+ G+SS+G+S SNS + + +T + + P
Sbjct: 1244 ASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKP 1303
Query: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSP 612
K ++ + ++ K R +S + K E K + + + +ER R + P
Sbjct: 1304 KEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEP 1363
Query: 613 SRERRRSRS-------------------RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNS 653
SRER ++ +S R++ R + RRKID ++
Sbjct: 1364 SRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSST 1423
Query: 654 HKHKG-EAKEQERK-----------KERSRSIDKDRKKKDKEREREQDKRKEKQKREEKD 701
K E KE K K + R +DK K +ER RE++K+ EK ++E K
Sbjct: 1424 VKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERK- 1482
Query: 702 FKFSSQDDR------LKRKRESERTF--SRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG 753
+ S +DR KR++E T S+ S S + + +D +K+ +K S K G
Sbjct: 1483 -RDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKG 1541
Query: 754 SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
SDS + S +K+++ K + ++ GK+ + HKS + R
Sbjct: 1542 SDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR 1593
Score = 66.2 bits (160), Expect = 1e-10
Identities = 67/322 (20%), Positives = 132/322 (40%), Gaps = 35/322 (10%)
Query: 431 KEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETT 490
KE K+ E+EK++ T + K+ E D K+RTP
Sbjct: 1267 KENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDK 1326
Query: 491 SVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS------------STVSSSSYSS 538
+ KKE K K+++ ++ ++ S S+ R S V +
Sbjct: 1327 EKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTP 1386
Query: 539 SSGSSRTS-SRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRS 597
SGS ++ RS P+ ++ R + T + S I+++ + A++ I
Sbjct: 1387 VSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYINHTPPP 1446
Query: 598 NRNSIERER-RRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI--------DDQRGN 648
S ERE +++ SRER R R + ++ R S + R++ ++ G
Sbjct: 1447 LSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTKRRKEENGT 1506
Query: 649 LSGNSHKHKGEAK-----EQERKKERSRSIDKDRKKKDKERER--------EQDKRKEKQ 695
+ + HK + + E++++K +S+S K++ + E+ +++ R +K+
Sbjct: 1507 MGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGGKKESRHDKE 1566
Query: 696 KREEKDFKFSSQDDRLKRKRES 717
K E+K+ + SS K+ +S
Sbjct: 1567 KIEKKEKRDSSGGKEEKKHHKS 1588
Score = 52.4 bits (124), Expect = 2e-06
Identities = 74/346 (21%), Positives = 126/346 (36%), Gaps = 75/346 (21%)
Query: 237 REGLEKMEREKQKKLEKERMEQQRSQLS-------KKEKKATEDAEGGDGPRLPQRSKFD 289
++G EK + E+ K EK R ++R+ S KKE+KA ++ P +S +
Sbjct: 1297 KDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQE 1356
Query: 290 SDEEEEDT------------ENVEAASSGKVTRS-PSPVPQEEHSDPEMTEEEKEYQMML 336
+ E+E + ENV+ V+ S SPVP+ + +PE ++ +
Sbjct: 1357 REREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRR------ 1410
Query: 337 LTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDS 396
+I +H K +L +SSA + +
Sbjct: 1411 ----------------KIDTHPSPSHSSTVKDSLIELKESSAKLYIN--------HTPPP 1446
Query: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMN 456
+ +R + D D R R R+K++ RKE+++ +++ +TK
Sbjct: 1447 LSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRD-----HSNNDREVPPDLTKR-- 1499
Query: 457 EFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSG 516
KE+N V K +P E+ P K+KEK SG
Sbjct: 1500 ---RKEENGTM---------GVSKHKSESPCES-----PYPNEKDKEKNKSKSSGKEKGS 1542
Query: 517 SSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR-SSSPKRKKRHSRS 561
S + + SS S + R SS K +K+H +S
Sbjct: 1543 DSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKS 1588
Score = 34.3 bits (77), Expect = 0.47
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 8/127 (6%)
Query: 195 PQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKE 254
P + S + + S L + PP + K R + + + RE++KK EK+
Sbjct: 1418 PSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKD 1477
Query: 255 RMEQQRSQLSKKEK---KATEDAEGGDGPRLPQRSKFDSDEE-----EEDTENVEAASSG 306
R E++R + + T+ + +G + K +S E E+D E ++ SSG
Sbjct: 1478 RKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSG 1537
Query: 307 KVTRSPS 313
K S S
Sbjct: 1538 KEKGSDS 1544
Score = 32.7 bits (73), Expect = 1.4
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 191 PPAPPQNRRERPSSF---RDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREK 247
PP + R+E + + + SP P P + D K ++ + +G + + EK
Sbjct: 1493 PPDLTKRRKEENGTMGVSKHKSESPCESPY---PNEKDKEKNKSKSSGKEKGSDSFKSEK 1549
Query: 248 QKKLEKERMEQQRSQLSKKEKKATEDAEGG 277
K+ ++ R K EKK D+ GG
Sbjct: 1550 MDKISSGGKKESRHDKEKIEKKEKRDSSGG 1579
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 88.6 bits (218), Expect = 2e-17
Identities = 59/219 (26%), Positives = 107/219 (48%), Gaps = 23/219 (10%)
Query: 574 RSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
R R+ + + + + RDR+R N ERE +R R+R R R RDR+T+R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERE-------NRHRQRDRHRERDRQTDR--- 52
Query: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR-KKKDKEREREQDKRK 692
+ R+R+K D++ + + +E++R++ER R D++R K +D+ER+RE D+ +
Sbjct: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
Query: 693 EKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS 752
E+ ++ ++ +D + +R+R+ ER R R RQ +K T D ++
Sbjct: 113 ERNRKGGRE-----RDKQTERERDRERERQRQRE------RERQRQRERKRET-DRERQR 160
Query: 753 GSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSG 791
++ R KE+K KK + R ++ G
Sbjct: 161 WAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
Score = 87.0 bits (214), Expect = 6e-17
Identities = 57/205 (27%), Positives = 93/205 (45%), Gaps = 10/205 (4%)
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSP 552
+E ++E K + +G+ N + R R
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSP 612
+R ++ R R + R R R R K +++R R K RDR R + +R R RNR
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER--KRETDRNRERNRKG 118
Query: 613 SRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRS 672
RER + R RDR R R R R+R++ QR + + A+ +ERKKER
Sbjct: 119 GRERDKQTERERDRERER-QRQRERERQR---QRERKRETDRERQRWAEREERKKERK-- 172
Query: 673 IDKDRKKKDKEREREQDKRKEKQKR 697
K+RKK+ KE+++E+ +R++K+++
Sbjct: 173 --KERKKERKEKKKEEKRREDKKRK 195
Score = 87.0 bits (214), Expect = 6e-17
Identities = 55/202 (27%), Positives = 105/202 (51%), Gaps = 28/202 (13%)
Query: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSP 612
+R+++ R + R R R + + E+ R + RDR R +RE+ R R
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTEREN---RHRQRDRHRERDRQTDREKERERQK 60
Query: 613 SRERRRSRSRSRDRRTNRA-SRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
R+R+R R R +R T R R R R+R++ D + + + +++ERK+E R
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTD----------RERDKDRDRERKRETDR 110
Query: 672 SIDKDRK---KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
+ +++RK ++DK+ ERE+D+ +E+Q++ E++ + + +RKRE++R R
Sbjct: 111 NRERNRKGGRERDKQTERERDRERERQRQRERE-----RQRQRERKRETDRERQRWAE-- 163
Query: 729 VKIIRHDSRQDSKKSTTKDSKK 750
R + +++ KK K+ K+
Sbjct: 164 ----REERKKERKKERKKERKE 181
Score = 86.3 bits (212), Expect = 1e-16
Identities = 53/174 (30%), Positives = 95/174 (54%), Gaps = 15/174 (8%)
Query: 553 KRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIER--ERRRNR 610
++++R +++ +R R R R+ E R R K RDR+R ER ER+R R
Sbjct: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRER 82
Query: 611 SPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERS 670
RER+R R RD+ +R R R DR + +++G + + +E+ER+++R
Sbjct: 83 QRQRERKRQTDRERDKDRDR-ERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRE 141
Query: 671 RSIDKDRKKK---DKERER--EQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
R + R++K D+ER+R E+++RK+++K+E K +R ++K+E +R
Sbjct: 142 RERQRQRERKRETDRERQRWAEREERKKERKKERK-------KERKEKKKEEKR 188
Score = 82.0 bits (201), Expect = 2e-15
Identities = 51/204 (25%), Positives = 100/204 (49%), Gaps = 22/204 (10%)
Query: 603 ERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
ER+R +R ER R R R R+ +T R +R R RDR + D++ + KE
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTD----------REKE 55
Query: 663 QERKKERSRSIDKDRK-KKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
+ER+KER R ++R+ +++ ER+RE+ +++E++++ +++ +D +RKRE++R
Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRE---RDKDRDRERKRETDRNR 112
Query: 722 SRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
R+ R R+ K++ + ++ R +E ++ + +
Sbjct: 113 ERN--------RKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
Query: 782 RSVEKSQRSGKKASRKHKSKSRSR 805
+K ++ +K RK K K R
Sbjct: 165 EERKKERKKERKKERKEKKKEEKR 188
Score = 53.5 bits (127), Expect = 8e-07
Identities = 65/295 (22%), Positives = 106/295 (35%), Gaps = 101/295 (34%)
Query: 399 ERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEF 458
ER +D E R R RQ++ + + + D+ E + +QT+R
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERD-RQTDR-------- 52
Query: 459 IHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
KE+ R+ + D +++R T ++ +E+++Q
Sbjct: 53 -EKERE-------RQKERDRQRQRERETERETERQRERQRQRERKRQ------------- 91
Query: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
+ R + +RK+ R+R K R R + R
Sbjct: 92 -----------------------TDRERDKDRDRERKRETDRNRERNRKGGRERDKQTER 128
Query: 579 RIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
RDR ERER+R R R+R+R R R DR R + R+
Sbjct: 129 E------------RDR--------ERERQRQRERERQRQRERKRETDRERQRWA---ERE 165
Query: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE 693
RK +ERKKER K+RK+K KE +R +DK+++
Sbjct: 166 ERK---------------------KERKKERK----KERKEKKKEEKRREDKKRK 195
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/153 (20%), Positives = 71/153 (46%), Gaps = 14/153 (9%)
Query: 664 ERKKERSRSIDKDR---KKKDKERERE-----QDKRKEKQKREEKDFKFSSQDDRLKRK- 714
ER++ER R D+ + +++D++RERE +++ +++ + E+D + + +R ++K
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTT-----KDSKKHSGSDSSGRSSSESPGSSK 769
R+ +R R + R RQ +K T KD + ++ G +
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 770 EKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
K + + R R ++ + ++ R+ K ++
Sbjct: 122 RDKQTERERDRERERQRQRERERQRQRERKRET 154
Score = 43.5 bits (101), Expect = 8e-04
Identities = 30/158 (18%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Query: 661 KEQERKKERSRSIDKDRKK-KDKERE---------REQDKRKEKQK---REEKDFKFSSQ 707
+++ERK+E R + +R++ + +ERE R++D+ +E+ + RE++ + +
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 708 DDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS 767
D + +R+RE+ER R + R RQ ++ ++ R + G
Sbjct: 63 DRQRQRERETERETERQRERQRQ--RERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 768 SKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
++K+ ++ + + +R ++ + + R R
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRER 158
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 87.8 bits (216), Expect = 4e-17
Identities = 91/283 (32%), Positives = 122/283 (43%), Gaps = 32/283 (11%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
+NRA + R R + RR +RSP R RSRSRS RR+
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
Query: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
+ RSRSR RR R S +S +K K+ S+ +K KK + E + E
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGELQEESP 176
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
+ + Q+ + F+ S ES F++S + I S D +
Sbjct: 177 LKSKSQEEPKDTFEHDSS--------ESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPS 228
Query: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
+ S S S++P S AK S S++ S +RSG
Sbjct: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
Score = 55.5 bits (132), Expect = 2e-07
Identities = 88/398 (22%), Positives = 160/398 (40%), Gaps = 52/398 (13%)
Query: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIRQKQEAFWRKEKEQQLLH 437
G + ++ED R R S +D T++E L+++ + + + ++ +
Sbjct: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
Query: 438 DKQMEE----EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
DK E E+ T TK+ ++ K +++ + ++ V +EK + + + L
Sbjct: 457 DKHKETGYVVERPST---TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
Query: 494 EPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSRS 549
+ +EK ++ R +S S + + S+ +S R +S
Sbjct: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
Query: 550 SSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRSN 598
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 574 VHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSY 633
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
+ + E R +SP RR S S R+ D R ++R N KG
Sbjct: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRK----------DTRLAGEERVFKEENQ---KG 680
Query: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLKR 713
+ K + + ID RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 681 DKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKH 740
Query: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
KRE + + S S S S ++SKK ++ K H
Sbjct: 741 KREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Score = 52.8 bits (125), Expect = 1e-06
Identities = 137/711 (19%), Positives = 260/711 (36%), Gaps = 116/711 (16%)
Query: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQFD 165
P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 221 PRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
Query: 166 YQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQID 225
++ +P QN P +RSP Q P+ +
Sbjct: 280 SRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPRDE 312
Query: 226 AVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQR 285
+ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 313 S---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE---- 365
Query: 286 SKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT---K 339
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L K
Sbjct: 366 -KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQGK 419
Query: 340 MLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGLGG 390
T + +E + Y +K D R+ K+ S T
Sbjct: 420 SFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTK------ 473
Query: 391 YGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKEQQ 434
ED+ S+R + +T E L + ++++ +R+E +
Sbjct: 474 -DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLR 532
Query: 435 LLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE 494
+ K + + + E K + SL + R +V+ K+ E S+ +
Sbjct: 533 I---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSIFD 588
Query: 495 PKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
H + + +S S S S S + T+S S + S+R
Sbjct: 589 ----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQ 644
Query: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
SP+ +R S P+ + +R R K E+ + K+R R+ I+ R+
Sbjct: 645 KSPEIHRRIDIS--PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRK-- 700
Query: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
ER + R S+ R +R SR + + + + + + HK + +
Sbjct: 701 -----ERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKRE-QDHSLSSSSSA 754
Query: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ------DDRLKRKRESERTFSR 723
S S R++K+ ++ERE++ + + +E F S+ DDR + +++
Sbjct: 755 SPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDR----DDGVDYWAK 810
Query: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG--RSSSESPGSSKEKK 772
G R R + KKS + H G E+ +++EKK
Sbjct: 811 RGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKK 861
Score = 46.6 bits (109), Expect = 9e-05
Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDR------RTNRASRSRSRDRRKIDDQRGNLSGN 652
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + N
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
Query: 653 -------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
++ +G Q R + R +R + R K S
Sbjct: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 119
Query: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
SQ R + +R + S S S + SK+ + S++ + G ESP
Sbjct: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGELQEESP 176
Query: 766 GSSKEKKAKKP--KHSRSRSVEKSQRS 790
SK ++ K +H S S+++ +S
Sbjct: 177 LKSKSQEEPKDTFEHDSSESIDEFNKS 203
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
Query: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
R+ R + R G V RH SR S K+ + +
Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
Query: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
Score = 43.9 bits (102), Expect = 6e-04
Identities = 76/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
+ ++A+G++ E +P ++ S EPK EH E S++ G
Sbjct: 163 QTKKAEGELQEE---SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDX 219
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
R S N R SP RS ++ A R SR R
Sbjct: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
Query: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
Query: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
Query: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 440 VSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
Score = 43.9 bits (102), Expect = 6e-04
Identities = 87/427 (20%), Positives = 165/427 (38%), Gaps = 47/427 (11%)
Query: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
S+++ S++G + +D+E K E+ +K + + ++ E+ +Q + V +
Sbjct: 359 SKEKGSEKGRAEGEWEDQEALDYFSDK-ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
Query: 456 NEFIH------------KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE----PKKEH 499
+ K ++ +SL RE+DG EK ET V+E K +H
Sbjct: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDG-FREEKNDKHKETGYVVERPSTTKDKH 476
Query: 500 KEKEKQGRSRSGSSSSGSSSS-NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKR- 557
KE++K + + S S S + + +++ R SP R K
Sbjct: 477 KEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMI 536
Query: 558 HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR--NSIERER--RRNRSPS 613
S S P +K + + +SNR +DR ++ +S+++E+ R
Sbjct: 537 ASDSHRPEVKLKMAPVPLD------DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI 590
Query: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE----- 668
+ + S+S S + S + LS ++ +E +++
Sbjct: 591 KLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIH 650
Query: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-----DRLKRKRESERTFSR 723
R I +KD E+ KE+ ++ +K + S D D +++R ER S+
Sbjct: 651 RRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSK 710
Query: 724 SGSISVKIIRHDSRQDSKKS--TTKDSKKHS-----GSDSSGRSSSESPGSSKEKKAKKP 776
S + + K + KD KH SS +S SP S +EK++KK
Sbjct: 711 GSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKE 770
Query: 777 KHSRSRS 783
+ ++
Sbjct: 771 REEEFKT 777
Score = 42.0 bits (97), Expect = 0.002
Identities = 97/464 (20%), Positives = 160/464 (34%), Gaps = 48/464 (10%)
Query: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
E E K K ++ R +E+K + E G P +K EE++++E +
Sbjct: 430 EEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK 489
Query: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
K T+SP V E+ D + K E + I +A D+HR
Sbjct: 490 ---KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
Query: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
K AP L S+ ASLT L + E+ R S T +
Sbjct: 543 PEVKLKMAPV-PLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
Query: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE---QNS 465
++H + K++ F + L ++ +K E T++ + IH+ S
Sbjct: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
Query: 466 LSLLEAREADGDVVNEKKRTPNE-----TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
+ R A + V +++ + ++ L +H+ KE RS+ S GS S
Sbjct: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE---RSKERGDSKGSRES 715
Query: 521 NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRI 580
+ Y S S+ KR++ HS S S + SR
Sbjct: 716 RGSRKQEKTPKDYKEYKSYKDDSK-------HKREQDHSLSSSSSASPSSPSSREEKESK 768
Query: 581 KIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640
K + + S + R R +R R R + R R R
Sbjct: 769 KEREEEFKTHHEMKEYSGFAGVSRPRGTFHD---DRDDGVDYWAKRGRGRGTFQRGRGRF 825
Query: 641 KIDDQRGNLSGNSHKHKGEA-KEQERKKERSRSIDKDRKKKDKE 683
+ N K++G+ E E + + KDR K++KE
Sbjct: 826 NFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
Score = 37.7 bits (86), Expect = 0.043
Identities = 23/66 (34%), Positives = 32/66 (48%)
Query: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
+ H ++GRSRS S S SS S + + SS SS S +S S SP K+
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
Query: 557 RHSRSR 562
R S+ +
Sbjct: 157 RGSQEK 162
Score = 34.3 bits (77), Expect = 0.47
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
R+P S K ++ RSR S S +SR+ +SS+ SSS YS S S
Sbjct: 101 RSPRRGRSRSRSPKRRSVSSQRSRSR-----SRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
Query: 544 RTSSRSSSPKRKKRHSRSRSP 564
R S+ K+ + + SP
Sbjct: 156 RRGSQEKQTKKAEGELQEESP 176
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 87.4 bits (215), Expect = 5e-17
Identities = 52/207 (25%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR------- 578
+T + S S+ S + R S R + +++ R R K R + R
Sbjct: 14 NTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK 73
Query: 579 ---RIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSR 635
R + E + R + R++ R R +++R R + RER++ + R R N+ R R
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 636 SRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE-RSRSIDKDRKKKDKEREREQDKRKEK 694
R +R+ +R + K E K ++RKKE R + +++RK++ KERER++ + ++K
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Query: 695 QKREEKDFKFSSQDDRLKRKRESERTF 721
++++E+ K + DR ++ + F
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDSQVF 220
Score = 84.0 bits (206), Expect = 5e-16
Identities = 66/235 (28%), Positives = 94/235 (40%), Gaps = 44/235 (18%)
Query: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPK 553
E KKE +E+EK+ R R R + K
Sbjct: 35 ERKKERREREKRKREREKERK-----------------------------RERGKKEKKK 65
Query: 554 RKKRH-----SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRR 608
RKKR R R K R+ R R+ K E + K R RR + +ER R
Sbjct: 66 RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 609 NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
RER+R + R + RR R R ++R K + +R + K E +ERKKE
Sbjct: 126 ENKQRRERKRKKRRKKKRRKER---KREKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
Query: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
R R K+ +ER++E+ K + K+K +KD K Q D + E F+R
Sbjct: 183 RER-------KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
Score = 82.8 bits (203), Expect = 1e-15
Identities = 62/194 (31%), Positives = 95/194 (48%), Gaps = 13/194 (6%)
Query: 569 RRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT 628
+R R RR + + R R K R R R + +R ++R R RER+R + R + R+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKR-KKRERGKERERKR-KEREKQRKE 88
Query: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER--KKERSRSIDKDRKK---KDKE 683
R R R + K +R K K E KE+ER K+ R R K RKK K+++
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 684 REREQDKRKEKQKREEKDFKFSSQD-DRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
RE+E+ KR+ K+K+ +K+ + ++ +R +RK+E ER R K + KK
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK-----KERRKKK 203
Query: 743 STTKDSKKHSGSDS 756
KD K +DS
Sbjct: 204 ERKKDRKTDRQTDS 217
Score = 82.0 bits (201), Expect = 2e-15
Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 43/241 (17%)
Query: 580 IKIESNRARVKIRDR--------------RRSNRNSIERERRRNRSPSRERRRSRSRSRD 625
+K S+RA VK+ +R + ER R R RE+ R R R +
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKK 61
Query: 626 RRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRK-----KK 680
+ R R R ++R + +R K + E +E+ER+K + ++RK ++
Sbjct: 62 EKKKRKKRERGKERERKRKER-------EKQRKERREKERRKRKKEKKKRERKQRGRRER 114
Query: 681 DKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
K++ER++ +R+ KQ+RE K K + R +RKRE ER + + ++
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG------------KRERKRKK 162
Query: 741 KKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKS 800
+K ++ K+ R + KE++ +K + + R +K ++ +K R+ S
Sbjct: 163 RKKEEREKKR-----ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
Query: 801 K 801
+
Sbjct: 218 Q 218
Score = 77.4 bits (189), Expect = 5e-14
Identities = 50/200 (25%), Positives = 92/200 (46%), Gaps = 21/200 (10%)
Query: 603 ERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKE 662
E ER++ R +R+R R + R R + + + + R + G + K + +E
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRER---------GKERERKRKERE 83
Query: 663 QERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFS 722
++RK+ R + K RKK+ K+RER+Q R+E++K++E+ + R +RKR+ R
Sbjct: 84 KQRKERREKERRK-RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 723 RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSR 782
R R + +++ ++ K +K R + KK ++ K R R
Sbjct: 143 R---------RKERKREKERG--KRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Query: 783 SVEKSQRSGKKASRKHKSKS 802
E+ + KK RK K+
Sbjct: 192 KKERKKERRKKKERKKDRKT 211
Score = 72.4 bits (176), Expect = 2e-12
Identities = 46/181 (25%), Positives = 90/181 (49%), Gaps = 13/181 (7%)
Query: 626 RRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERE 685
R + R R R++RK + ++ + K E ++E+KK + R K+R++K KERE
Sbjct: 32 RESERKKERREREKRKREREK--------ERKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 686 REQDKRKEKQKR---EEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKK 742
+++ +R+EK++R +EK + Q R +RK++ ER + + + R+ KK
Sbjct: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR--KK 141
Query: 743 STTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
K+ K+ R + +EKK ++ + R + E+ +R +K RK + +
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 803 R 803
+
Sbjct: 202 K 202
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/145 (26%), Positives = 76/145 (52%), Gaps = 4/145 (2%)
Query: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERT 720
+E ERKKER R +K +++++KER+RE+ K KEK+KR++++ + +R +++RE +R
Sbjct: 32 RESERKKER-REREKRKREREKERKRERGK-KEKKKRKKRE--RGKERERKRKEREKQRK 87
Query: 721 FSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSR 780
R + R+ ++ + KK + + K+++ KK + R
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
Query: 781 SRSVEKSQRSGKKASRKHKSKSRSR 805
R E+ +R K+ RK + + + R
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKR 172
Score = 60.8 bits (146), Expect = 5e-09
Identities = 58/256 (22%), Positives = 99/256 (38%), Gaps = 59/256 (23%)
Query: 445 KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEK 504
K T+R ++ E +E+ + R+ + +KKR E E +++ KE+EK
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK--ERERKRKEREK 84
Query: 505 QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSP 564
Q + R + R ++KK+ + R
Sbjct: 85 QRKERREKERRKRKKEKKKRER-------------------KQRGRRERKKKKERKERER 125
Query: 565 TIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRS- 623
K RR R R R+ K R R K R +R ER+R++ + RE++R R+R
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKR-------ERKRKKRKKEEREKKRERNRKE 178
Query: 624 -RDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
+ R + R R ++R+ KE+ +KKER KKD+
Sbjct: 179 RKKERERKERRERKKERK--------------------KERRKKKER---------KKDR 209
Query: 683 EREREQDKRKEKQKRE 698
+ +R+ D + + RE
Sbjct: 210 KTDRQTDSQVFRPLRE 225
Score = 55.1 bits (131), Expect = 3e-07
Identities = 56/242 (23%), Positives = 96/242 (39%), Gaps = 57/242 (23%)
Query: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHD-KQMEEEKQQTERVTK 453
+SE ++ R E + E+ R R R K+E RK++E+ + K+ E EKQ+ ER K
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 454 EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSS 513
E + KE+ + + E+K E E K++ + K+K+ + R
Sbjct: 93 ERRKR-KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 514 SSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
G KRKKR R + +R R+
Sbjct: 152 ERGKRER--------------------------------KRKKRKKEER----EKKRERN 175
Query: 574 RSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
R ++R++ RER++ R +ERR+ + R +DR+T+R +
Sbjct: 176 R-----------------KERKKERERKERRERKKER--KKERRKKKERKKDRKTDRQTD 216
Query: 634 SR 635
S+
Sbjct: 217 SQ 218
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/185 (19%), Positives = 65/185 (35%)
Query: 398 DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNE 457
+ +R E + ++ + R R K+ RKE+E+Q ++ E K++ E+ +E +
Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108
Query: 458 FIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGS 517
+E+ + RE + E+KR + +K KE+ K+ R R
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 518 SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYS 577
R R R +RKK R + R S
Sbjct: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAF 228
Query: 578 RRIKI 582
R+ +
Sbjct: 229 NRVTV 233
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 31/121 (25%)
Query: 685 EREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKST 744
+RE +++KE+++RE++ KR+RE ER R+ KK
Sbjct: 31 QRESERKKERREREKR-----------KREREKER----------------KRERGKKEK 63
Query: 745 TKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
K K+ G + + K++K ++ K R R EK +R K+ R+ + K +
Sbjct: 64 KKRKKRERGKERERKRKER----EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
Query: 805 R 805
R
Sbjct: 120 R 120
Score = 40.8 bits (94), Expect = 0.005
Identities = 39/229 (17%), Positives = 88/229 (38%), Gaps = 35/229 (15%)
Query: 233 PAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDE 292
P RE K ER +++K ++ER ++++ + KKEKK + E G ++ + +
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
Query: 293 EEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDE 352
E + E + K +E E E E+E + K
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK------------- 134
Query: 353 EIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDD 412
K +K + K+ + G E +R R E +
Sbjct: 135 -----RKKRRKKKRRKERKREKE-----------------RGKRERKRKKRKKEEREKKR 172
Query: 413 EELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHK 461
E R ++++E R+E++++ +++ ++E+++ + ++ + + +
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
Score = 39.3 bits (90), Expect = 0.015
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 199 RERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQ 258
RER R++QR +++ + + KR RE +K ER+++++ K+R E+
Sbjct: 75 RERKRKEREKQRKERREKERRKRKK-EKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 259 QRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTE 298
+R + KK+++ E G R +R K +E E+ E
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRE 173
Score = 38.9 bits (89), Expect = 0.019
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 14/136 (10%)
Query: 196 QNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER 255
+ RRER R+R++ K+E + + KR+ ++ EREKQ+K +E+
Sbjct: 38 KERREREKRKREREKER-----KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 256 MEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPV 315
++R KKEKK E + G R K + +E + EN + + R
Sbjct: 93 ERRKR----KKEKKKRERKQRGRRER-----KKKKERKERERENKQRRERKRKKRRKKKR 143
Query: 316 PQEEHSDPEMTEEEKE 331
+E + E + E++
Sbjct: 144 RKERKREKERGKRERK 159
Score = 30.8 bits (68), Expect = 5.2
Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 2/137 (1%)
Query: 196 QNRRERPSSF-RDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKE 254
+ +RER R+R + K+E + KR+ +E EK R K+KK +K+
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR-KRKKEKKK 103
Query: 255 RMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP 314
R +QR + +K+KK ++ E + R ++ K ++ E + +
Sbjct: 104 RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
Query: 315 VPQEEHSDPEMTEEEKE 331
+E E +E++
Sbjct: 164 KKEEREKKRERNRKERK 180
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 87.4 bits (215), Expect = 5e-17
Identities = 94/283 (33%), Positives = 128/283 (45%), Gaps = 32/283 (11%)
Query: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
Query: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEES 175
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 176 PLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
Query: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
S S S S++P S AK S S++ S +RSG
Sbjct: 233 PPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
Score = 57.0 bits (136), Expect = 7e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 457 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 512
Query: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 513 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 572
Query: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 573 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 632
Query: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 633 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 679
Query: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 680 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 739
Query: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
KRE + + S S S S ++SKK ++ K H
Sbjct: 740 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 219 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 277
Query: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
++ +P QN P +RSP Q P+
Sbjct: 278 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 310
Query: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 311 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 365
Query: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 366 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 417
Query: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
K T + +E + Y +K D R+ K+ S T
Sbjct: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 473
Query: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 474 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 530
Query: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 531 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 586
Query: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
+ H + + +S S S S S + T++ S + S+
Sbjct: 587 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 642
Query: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 643 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 700
Query: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 701 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 759
Query: 658 GEAKEQERKKERSRSIDKDRKKKD 681
+E+E KKER + K+
Sbjct: 760 SSREEKESKKEREEEFKTHHEMKE 783
Score = 47.4 bits (111), Expect = 5e-05
Identities = 94/472 (19%), Positives = 170/472 (36%), Gaps = 51/472 (10%)
Query: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 430 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 486
Query: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 487 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
Query: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
K AP L S+ ASLT L + E+ R S T +
Sbjct: 543 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
Query: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL 468
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRR------ 652
Query: 469 LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
++ T + T + ++ KE+ ++G + S+ R
Sbjct: 653 ----------IDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 702
Query: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRAR 588
S S GS +S K K + +S ++ R + +SR ++ +
Sbjct: 703 S----KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
Query: 589 VKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSR----DRRTNRASRSRSRDRRKIDD 644
R+ + S + E + + SR R D R + R R +
Sbjct: 759 PSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF 818
Query: 645 QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
QRG N K G + + K + I +D ++ + E ++D+RKE+++
Sbjct: 819 QRGRGRFN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
Score = 46.6 bits (109), Expect = 9e-05
Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDR------RTNRASRSRSRDRRKIDDQRGNLSGN 652
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + N
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
Query: 653 -------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
++ +G Q R + R +R + R K S
Sbjct: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 119
Query: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
SQ R + +R + S S S + SK+ + S++ + G ESP
Sbjct: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEESP 176
Query: 766 GSSKEKKAKKP--KHSRSRSVEKSQRS 790
SK ++ K +H S S+++ +S
Sbjct: 177 LKSKSQEEPKDTFEHDPSESIDEFNKS 203
Score = 44.7 bits (104), Expect = 3e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 64
Query: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
R+ R + R G V RH SR S K+ + +
Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
Query: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 163 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 219
Query: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
Query: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
R S N R SP RS ++ A R SR R
Sbjct: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
Query: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
Query: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
Query: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 440 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
Score = 40.0 bits (92), Expect = 0.009
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 131 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 190
Query: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
E ++EF S + A + R+P+ + + P +
Sbjct: 191 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 246
Query: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 247 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
Query: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
+ SR RS + +R E +R R RD+ S E
Sbjct: 306 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 365
Query: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
+ R N S + + + R++ A + +S
Sbjct: 366 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 425
Query: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 426 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 485
Query: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 486 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 544
Query: 741 KK 742
K
Sbjct: 545 VK 546
Score = 39.7 bits (91), Expect = 0.011
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 58 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 110
Query: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 111 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
Query: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
Query: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
+ + ML T T + + + +
Sbjct: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
Query: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 289 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 346
Query: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 347 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 401
Query: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 402 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 461
Query: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 462 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 511
Query: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
N ++ E+ R SP R + R S ++DR
Sbjct: 512 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 571
Query: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 572 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 631
Query: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
++ ++ +QK E + L++ ER F K +R
Sbjct: 632 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 691
Query: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 692 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 751
Query: 786 KSQRSGKKASRKHKSKSRSR 805
S +SR+ K + R
Sbjct: 752 SSASPSSPSSREEKESKKER 771
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 87.0 bits (214), Expect = 6e-17
Identities = 90/419 (21%), Positives = 154/419 (36%), Gaps = 41/419 (9%)
Query: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE-- 462
++ + DEE + R + + A +E + +E + KE E I +
Sbjct: 190 NDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFP 249
Query: 463 -----------QNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSG 511
+ ++ +E E D+++ + +T LE +K KEKE+Q +
Sbjct: 250 VAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER 309
Query: 512 SSSSGSSS-SNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARR 570
R R R R K R R R
Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
R RS R + +R+R K RDR R ERER R R RER R R R R+R
Sbjct: 370 DRERSSDRNK--DRSRSREKSRDRERERERERERERERERERERERERERERERER---E 424
Query: 631 ASRSRSRDRRKIDDQRGNLSGNSHK-HKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
+ + RDR + ++ K + EA QER K K ++ +KE ERE++
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484
Query: 690 KRKE--KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
+R+E K+ + K+F DDR + + R ++ ++ + ++ + K
Sbjct: 485 RRREMAKEAKRLKEFLEDYDDDR------DDPKYYRGSALQKRLRDREKEMEADERDRKR 538
Query: 748 SKK-------------HSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKK 793
K+ H D+ + + ++ + K+ S EK ++ K+
Sbjct: 539 EKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKR 597
Score = 76.3 bits (186), Expect = 1e-13
Identities = 55/219 (25%), Positives = 99/219 (45%), Gaps = 22/219 (10%)
Query: 590 KIRDRRRS---NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646
K RD + + E+ER+ RER R R R R+RR R R R+R K
Sbjct: 283 KFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK----- 337
Query: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDR---KKKDKEREREQDKRKEKQKREEKDFK 703
K + +E++R ++R++ D+DR + +D++RER D+ K++ + EK
Sbjct: 338 -------EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS-- 388
Query: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
++ +R+RE ER R + R R+ ++ K ++ D+ R E
Sbjct: 389 -RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447
Query: 764 SPGSSKEKK-AKKPKHSRSRSVEKSQRSGKKASRKHKSK 801
KE ++ K+ R +K++ K+A R+ + +
Sbjct: 448 RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Score = 76.3 bits (186), Expect = 1e-13
Identities = 76/400 (19%), Positives = 159/400 (39%), Gaps = 28/400 (7%)
Query: 394 GDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTK 453
G E ER + E + + E R R R+++E +E+E++ +++ E E+ + TK
Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTK 355
Query: 454 EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQ-GRSRSGS 512
E + +E++ RE D ++ R+ ++ ++ +E+E++ R R
Sbjct: 356 ERDRDRDRERDR---DRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412
Query: 513 SSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR 572
R + R R K R ++ I+ R+ +
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK-K 471
Query: 573 SRSYSRRIKIESNRARVKIRDRRRSNR--NSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
+R Y + + E R R ++ +R + +R + + R R R++
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531
Query: 631 ASRSRSRDRRKIDDQRGNLSGNSHKH-KGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
R R R++ ++++ R L H E + E++ ER R + + K++ E E E++
Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR---QPQIKQEPESEEEEE 588
Query: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVK-----------------II 732
+++EK+++ E+ + + ++ + + R S + S+S II
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIII 648
Query: 733 RHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKK 772
H++ D ++ K +S P S K KK
Sbjct: 649 PHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKK 688
Score = 62.8 bits (151), Expect = 1e-09
Identities = 59/275 (21%), Positives = 125/275 (45%), Gaps = 33/275 (12%)
Query: 538 SSSGSSRTSSRSSSPKRK-KRHSRSRSPTIK-ARRSRSRSYSRRIKIESNRARVKIRDRR 595
+S+G++R + ++ + ++ R IK A R YS + S + R ++
Sbjct: 178 ASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKK 237
Query: 596 RSNRNSIERERRRNRSP-------SRERRRSRSRSRDRRTNRASRSRSRDR---RKIDDQ 645
+ + I R R +P ++E + D+R + SR S+ R +K++++
Sbjct: 238 KEKKEDIFR--RFPVAPLIPYPLITKEDINAIEMEEDKR-DLISREISKFRDTHKKLEEE 294
Query: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
+G K + E +++ R++ER R +++R+++++ERERE+++ +EK+K E++ +
Sbjct: 295 KGK----KEKERQEIEKERRERERER--ERERERREREREREREREREKEKERERERERD 348
Query: 706 SQDDRLK---RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSS 762
DR K R R+ ER R + D K ++ +K +
Sbjct: 349 RDRDRTKERDRDRDRERDRDRD---------RERSSDRNKDRSRSREKSRDRERERERER 399
Query: 763 ESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
E + ++ ++ + R R E+ + KK R+
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDRE 434
Score = 59.7 bits (143), Expect = 1e-08
Identities = 57/263 (21%), Positives = 105/263 (39%), Gaps = 28/263 (10%)
Query: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
SS + S S S RKK+ + + + Y K + N ++ D+R
Sbjct: 219 SSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEME-EDKRDLI 277
Query: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
I + R ++ E+ + ++ R R R R+R + + +
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER-------------ERRE 324
Query: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
+E+ER++ER K+K++ERERE+D+ +++ K ++D DR R+R S+
Sbjct: 325 RERERERERER-------EKEKERERERERDRDRDRTKERDRDRDRERDRDR-DRERSSD 376
Query: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
R RS S R SR ++ + ++ R +E++ +K K
Sbjct: 377 RNKDRSRS------REKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Query: 779 SRSRSVEKSQRSGKKASRKHKSK 801
E+ +K RK + K
Sbjct: 431 RDREEDEEDAYERRKLERKLREK 453
Score = 57.4 bits (137), Expect = 5e-08
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 10/168 (5%)
Query: 643 DDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDF 702
+D+R +S K + K+ E +K + ++ +K+ +ERERE+++ +E+++RE +
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330
Query: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSS 762
+ ++ +R+RE ER R + D +D ++ +D ++ S + S
Sbjct: 331 REREREKEKERERERERDRDRD-----RTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 763 ESPGSSKEKKAKKPKHSRSRSVEKS-----QRSGKKASRKHKSKSRSR 805
E + ++ ++ + R R E+ +R ++ + K K R R
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Score = 46.6 bits (109), Expect = 9e-05
Identities = 50/275 (18%), Positives = 107/275 (38%), Gaps = 54/275 (19%)
Query: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAE-----GGDGPRLPQRSKFDSDEEEE 295
E+ ERE++++ E+ER E++R + ++E++ ++ E D R +R + D D E +
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR-DRDRERD 366
Query: 296 DTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIY 355
+ E +S RS S + E E+E +
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERER--------------------- 405
Query: 356 YVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDT-DDEE 414
++ R+ + ++ + +D++ DR + D + +
Sbjct: 406 --ERERERERERERERERERER------------------EKDKKRDREEDEEDAYERRK 445
Query: 415 LRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA 474
L ++R+K+ A+ + K ++ K+ E +++ ER + E + + LE +
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDD 505
Query: 475 DGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSR 509
D D + S L+ + +EKE + R
Sbjct: 506 DRDDPKYYR------GSALQKRLRDREKEMEADER 534
Score = 44.7 bits (104), Expect = 3e-04
Identities = 36/149 (24%), Positives = 63/149 (42%), Gaps = 6/149 (4%)
Query: 662 EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQ----KREEKDFKFSSQDDRLKRKRES 717
E++++ SR I K R K E + K KE+Q +R E++ + + +R +R+RE
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 718 ERTFSRSGSISVKIIR-HDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP 776
ER R + R D +D K +D + D SS+ + K
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 777 KHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
R R E+ +R ++ + + + R R
Sbjct: 390 DRERERERER-ERERERERERERERERER 417
Score = 44.7 bits (104), Expect = 3e-04
Identities = 56/295 (18%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 237 REGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEED 296
RE + ERE++++ E+ER ++ + KK + ++ + + +L ++ + +E
Sbjct: 401 REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460
Query: 297 TENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYY 356
+N E K +EE EM +E K + L E D D+ YY
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL-------EDYDDDRDDPKYY 513
Query: 357 VA-------KDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSD 409
+D ++ + + L + G+ D+E +R ++ E+
Sbjct: 514 RGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ--EAER 571
Query: 410 TDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQ-NSLSL 468
+++ ++E ++EKE++ + EEE +Q + + +S S
Sbjct: 572 RRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASG 631
Query: 469 LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSR 523
GD P+E + + +EH+ K S+S G +S R
Sbjct: 632 NATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKR 686
Score = 37.4 bits (85), Expect = 0.056
Identities = 68/359 (18%), Positives = 130/359 (36%), Gaps = 32/359 (8%)
Query: 200 ERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQ 259
E ++++R I ++ + + + R RE + E+EK+++ E+ER +
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 260 RSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEE 319
+ + E D R R+K D E + + E + R + E
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNK-DRSRSREKSRDRERERERERERERERERERE 410
Query: 320 HSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSAL 379
E E+E + K E DEE Y + RK + K+ A L
Sbjct: 411 REREREREREREREREKDKKRDREE------DEEDAYERRKLERKLRE---KEAAYQERL 461
Query: 380 ASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQE-----AFWRKEKEQQ 434
+ + + E ER + + + L+ + + ++R Q+
Sbjct: 462 KNWE-IRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 435 LLHD--KQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV----VNEKKRTPNE 488
L D K+ME +++ +R +E+ E + LL D D + ++ +
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQR------LLAEGHPDPDAELQRMEQEAERRRQ 574
Query: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTV----SSSSYSSSSGSS 543
EP+ E +E+EKQ + + T+ S+ S SS+SG++
Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNA 633
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.122 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,953,323
Number of Sequences: 37866
Number of extensions: 2258395
Number of successful extensions: 69444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1016
Number of HSP's successfully gapped in prelim test: 1664
Number of HSP's that attempted gapping in prelim test: 18672
Number of HSP's gapped (non-prelim): 22707
length of query: 805
length of database: 18,247,518
effective HSP length: 110
effective length of query: 695
effective length of database: 14,082,258
effective search space: 9787169310
effective search space used: 9787169310
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.