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Search of human proteins with 154091318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154091318 transient receptor potential cation channel,
subfamily M, member 3 isoform d [Homo sapiens]
(1544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154091318 transient receptor potential cation channel, subfam... 3102 0.0
gi|154091320 transient receptor potential cation channel, subfam... 3094 0.0
gi|154091314 transient receptor potential cation channel, subfam... 3094 0.0
gi|154091316 transient receptor potential cation channel, subfam... 3093 0.0
gi|154091310 transient receptor potential cation channel, subfam... 3088 0.0
gi|154091312 transient receptor potential cation channel, subfam... 3085 0.0
gi|154091308 transient receptor potential cation channel, subfam... 3080 0.0
gi|148612863 transient receptor potential cation channel, subfam... 1368 0.0
gi|18921093 transient receptor potential cation channel, subfami... 1265 0.0
gi|94538366 transient receptor potential cation channel, subfami... 1207 0.0
gi|4507689 transient receptor potential cation channel, subfamil... 528 e-149
gi|21314671 transient receptor potential cation channel, subfami... 474 e-133
gi|11225266 transient receptor potential cation channel, subfami... 466 e-130
gi|45935368 transient receptor potential cation channel, subfami... 464 e-130
gi|55953096 transient receptor potential cation channel, subfami... 450 e-126
gi|109689695 transient receptor potential cation channel, subfam... 286 1e-76
gi|209863032 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863030 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863026 transient receptor potential cation channel, subfam... 80 1e-14
gi|7706747 transient receptor potential cation channel, subfamil... 80 1e-14
gi|209863024 transient receptor potential cation channel, subfam... 78 6e-14
gi|6912736 transient receptor potential cation channel, subfamil... 71 7e-12
gi|209863028 transient receptor potential cation channel, subfam... 62 3e-09
gi|9966865 transient receptor potential cation channel, subfamil... 57 1e-07
gi|194733735 transient receptor potential cation channel, subfam... 57 2e-07
gi|4507687 transient receptor potential cation channel, subfamil... 57 2e-07
gi|5730102 transient receptor potential cation channel, subfamil... 54 9e-07
gi|21314682 transient receptor potential cation channel, subfami... 53 3e-06
gi|17505200 transient receptor potential cation channel, subfami... 50 1e-05
gi|4507685 transient receptor potential cation channel, subfamil... 47 2e-04
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 3102 bits (8042), Expect = 0.0
Identities = 1544/1544 (100%), Positives = 1544/1544 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
Query: 421 YTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWA 480
YTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWA
Sbjct: 421 YTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWA 480
Query: 481 VLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQL 540
VLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQL
Sbjct: 481 VLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQL 540
Query: 541 AVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMG 600
AVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMG
Sbjct: 541 AVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMG 600
Query: 601 RLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKE 660
RLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKE
Sbjct: 601 RLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKE 660
Query: 661 EEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGY 720
EEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGY
Sbjct: 661 EEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGY 720
Query: 721 LMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNV 780
LMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNV
Sbjct: 721 LMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNV 780
Query: 781 TDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGK 840
TDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGK
Sbjct: 781 TDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGK 840
Query: 841 MMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP 900
MMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP
Sbjct: 841 MMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP 900
Query: 901 PCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSIS 960
PCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSIS
Sbjct: 901 PCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSIS 960
Query: 961 NQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFI 1020
NQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFI
Sbjct: 961 NQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFI 1020
Query: 1021 TDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK 1080
TDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK
Sbjct: 1021 TDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK 1080
Query: 1081 ASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNS 1140
ASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNS
Sbjct: 1081 ASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNS 1140
Query: 1141 QEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLS 1200
QEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLS
Sbjct: 1141 QEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLS 1200
Query: 1201 LHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNI 1260
LHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNI
Sbjct: 1201 LHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNI 1260
Query: 1261 LGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQ 1320
LGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQ
Sbjct: 1261 LGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQ 1320
Query: 1321 NPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAE 1380
NPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAE
Sbjct: 1321 NPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAE 1380
Query: 1381 YTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAK 1440
YTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAK
Sbjct: 1381 YTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAK 1440
Query: 1441 GRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQ 1500
GRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQ
Sbjct: 1441 GRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQ 1500
Query: 1501 RNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
RNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1501 RNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 3094 bits (8021), Expect = 0.0
Identities = 1544/1554 (99%), Positives = 1544/1554 (99%), Gaps = 10/1554 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
Query: 421 YTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 470
YTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP
Sbjct: 421 YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 480
Query: 471 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 530
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL
Sbjct: 481 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 540
Query: 531 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 590
NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS
Sbjct: 541 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 600
Query: 591 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 650
QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE
Sbjct: 601 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 660
Query: 651 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 710
EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF
Sbjct: 661 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 720
Query: 711 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 770
WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV
Sbjct: 721 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 780
Query: 771 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 830
KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY
Sbjct: 781 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 840
Query: 831 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 890
LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY
Sbjct: 841 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 900
Query: 891 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 950
GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN
Sbjct: 901 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 960
Query: 951 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1010
NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD
Sbjct: 961 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1020
Query: 1011 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1070
ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE
Sbjct: 1021 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1080
Query: 1071 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1130
EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA
Sbjct: 1081 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1140
Query: 1131 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1190
YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL
Sbjct: 1141 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1200
Query: 1191 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1250
ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD
Sbjct: 1201 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1260
Query: 1251 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1310
IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS
Sbjct: 1261 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1320
Query: 1311 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1370
SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA
Sbjct: 1321 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1380
Query: 1371 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1430
NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP
Sbjct: 1381 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1440
Query: 1431 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1490
SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS
Sbjct: 1441 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1500
Query: 1491 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1501 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1554
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 3094 bits (8021), Expect = 0.0
Identities = 1544/1554 (99%), Positives = 1544/1554 (99%), Gaps = 10/1554 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN
Sbjct: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 573
Query: 421 YTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 470
YTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP
Sbjct: 574 YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 633
Query: 471 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 530
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL
Sbjct: 634 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 693
Query: 531 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 590
NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS
Sbjct: 694 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 753
Query: 591 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 650
QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE
Sbjct: 754 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 813
Query: 651 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 710
EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF
Sbjct: 814 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 873
Query: 711 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 770
WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV
Sbjct: 874 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 933
Query: 771 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 830
KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY
Sbjct: 934 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 993
Query: 831 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 890
LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY
Sbjct: 994 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 1053
Query: 891 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 950
GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN
Sbjct: 1054 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 1113
Query: 951 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1010
NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD
Sbjct: 1114 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1173
Query: 1011 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1070
ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE
Sbjct: 1174 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1233
Query: 1071 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1130
EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA
Sbjct: 1234 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1293
Query: 1131 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1190
YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL
Sbjct: 1294 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1353
Query: 1191 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1250
ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD
Sbjct: 1354 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1413
Query: 1251 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1310
IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS
Sbjct: 1414 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1473
Query: 1311 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1370
SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA
Sbjct: 1474 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1533
Query: 1371 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1430
NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP
Sbjct: 1534 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1593
Query: 1431 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1490
SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS
Sbjct: 1594 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1653
Query: 1491 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1654 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1707
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 3093 bits (8019), Expect = 0.0
Identities = 1544/1556 (99%), Positives = 1544/1556 (99%), Gaps = 12/1556 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 408
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 409 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 468
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 480
Query: 469 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 528
FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ
Sbjct: 481 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 540
Query: 529 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 588
ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT
Sbjct: 541 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 600
Query: 589 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 648
CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE
Sbjct: 601 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 660
Query: 649 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 708
AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV
Sbjct: 661 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 720
Query: 709 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 768
KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ
Sbjct: 721 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 780
Query: 769 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 828
KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN
Sbjct: 781 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 840
Query: 829 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 888
KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM
Sbjct: 841 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 900
Query: 889 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 948
IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV
Sbjct: 901 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 960
Query: 949 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1008
FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD
Sbjct: 961 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1020
Query: 1009 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1068
PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR
Sbjct: 1021 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1080
Query: 1069 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1128
LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD
Sbjct: 1081 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1140
Query: 1129 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1188
AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE
Sbjct: 1141 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1200
Query: 1189 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1248
KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH
Sbjct: 1201 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1260
Query: 1249 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1308
CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS
Sbjct: 1261 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1320
Query: 1309 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1368
FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY
Sbjct: 1321 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1380
Query: 1369 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1428
YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS
Sbjct: 1381 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1440
Query: 1429 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1488
HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR
Sbjct: 1441 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1500
Query: 1489 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1501 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1556
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 3088 bits (8006), Expect = 0.0
Identities = 1544/1569 (98%), Positives = 1544/1569 (98%), Gaps = 25/1569 (1%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 395
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 396 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 455
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 480
Query: 456 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 515
EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH
Sbjct: 481 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 540
Query: 516 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 575
EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL
Sbjct: 541 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 600
Query: 576 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 635
AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY
Sbjct: 601 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 660
Query: 636 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 695
MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL
Sbjct: 661 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 720
Query: 696 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 755
GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM
Sbjct: 721 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 780
Query: 756 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 815
REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII
Sbjct: 781 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 840
Query: 816 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 875
YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW
Sbjct: 841 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 900
Query: 876 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 935
KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL
Sbjct: 901 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 960
Query: 936 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 995
VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF
Sbjct: 961 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 1020
Query: 996 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1055
QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI
Sbjct: 1021 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1080
Query: 1056 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1115
RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES
Sbjct: 1081 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1140
Query: 1116 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1175
NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS
Sbjct: 1141 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1200
Query: 1176 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1235
FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS
Sbjct: 1201 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1260
Query: 1236 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1295
CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS
Sbjct: 1261 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1320
Query: 1296 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1355
IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV
Sbjct: 1321 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1380
Query: 1356 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1415
KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED
Sbjct: 1381 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1440
Query: 1416 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1475
LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY
Sbjct: 1441 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1500
Query: 1476 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1535
SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA
Sbjct: 1501 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1560
Query: 1536 FQSFESKHN 1544
FQSFESKHN
Sbjct: 1561 FQSFESKHN 1569
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 3085 bits (7998), Expect = 0.0
Identities = 1544/1566 (98%), Positives = 1544/1566 (98%), Gaps = 22/1566 (1%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 408
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 409 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVD 458
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVD
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 480
Query: 459 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 518
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 481 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 540
Query: 519 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 578
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 541 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 600
Query: 579 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 638
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 601 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 660
Query: 639 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 698
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 661 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 720
Query: 699 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 758
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 721 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 780
Query: 759 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 818
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 781 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 840
Query: 819 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 878
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 841 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 900
Query: 879 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 938
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 901 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 960
Query: 939 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 998
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 961 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1020
Query: 999 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1058
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1021 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1080
Query: 1059 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1118
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1081 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1140
Query: 1119 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1178
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1141 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1200
Query: 1179 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1238
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1201 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1260
Query: 1239 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1298
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1261 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1320
Query: 1299 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1358
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1321 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1380
Query: 1359 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1418
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1381 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1440
Query: 1419 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1478
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1441 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1500
Query: 1479 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1538
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1501 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1560
Query: 1539 FESKHN 1544
FESKHN
Sbjct: 1561 FESKHN 1566
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 3080 bits (7985), Expect = 0.0
Identities = 1544/1579 (97%), Positives = 1544/1579 (97%), Gaps = 35/1579 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 395
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 396 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRR 445
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRR
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 480
Query: 446 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 505
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 481 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 540
Query: 506 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 565
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 541 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 600
Query: 566 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 625
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 601 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 660
Query: 626 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 685
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 661 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 720
Query: 686 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 745
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 721 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 780
Query: 746 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 805
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 781 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 840
Query: 806 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 865
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 841 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 900
Query: 866 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 925
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 901 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 960
Query: 926 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 985
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 961 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1020
Query: 986 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1045
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 1021 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1080
Query: 1046 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1105
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1081 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1140
Query: 1106 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1165
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1141 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1200
Query: 1166 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1225
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1201 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1260
Query: 1226 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1285
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1261 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1320
Query: 1286 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1345
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1321 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1380
Query: 1346 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1405
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1381 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1440
Query: 1406 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1465
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1441 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1500
Query: 1466 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1525
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1501 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1560
Query: 1526 SMRRLSRTSAFQSFESKHN 1544
SMRRLSRTSAFQSFESKHN
Sbjct: 1561 SMRRLSRTSAFQSFESKHN 1579
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 1368 bits (3540), Expect = 0.0
Identities = 684/1192 (57%), Positives = 888/1192 (74%), Gaps = 82/1192 (6%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVR+S+DTKP+++L L+ KEWQ+ELPKL+ISVHGG+Q FEL P++KQ+ GKGLIKAA+TT
Sbjct: 108 YVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTT 167
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI TGGVNTGV +HVGDALK+HAS+S KICTIGIAPWG++EN+ DL+GRDVV PYQT
Sbjct: 168 GAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQT 227
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVA 181
+ NP+SKL VLN++HSHFIL D+GT GKYGAEV+LRR+LEK I+ Q+I+ RIGQGVPVVA
Sbjct: 228 LLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVA 287
Query: 182 LIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLL 241
LI EGGPNVI VLEYL+++PPVPVVVC+G+GRA+D+LA+ HK +EEGG + ++ ++
Sbjct: 288 LIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDII 347
Query: 242 VTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA 301
TI+KTF + + +A HLF LMECMK+KELITVF +GS+ HQDID+AILTALLKG NASA
Sbjct: 348 STIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASA 407
Query: 302 PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHR 361
DQL L LAW+RVDIA++ +F+YGQQW VGSLEQAMLDALV+DRV FVKLLIENGVSMH+
Sbjct: 408 FDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHK 467
Query: 362 FLTISRLEELYNTRHGPSNT-LYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
FLTI RLEELYNT+ GP+N L+HLVRDVK+GNLPP Y+I+LIDIGLVIEYLMGG YRC
Sbjct: 468 FLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCT 527
Query: 421 YTRKRFRTLYHNLFGPKRDDIPLRRGRKTT------------------------------ 450
YTRKRFR +Y++L G R R GR T+
Sbjct: 528 YTRKRFRLIYNSLGGNNR-----RSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIK 582
Query: 451 -----------------KKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW 493
KKR ++ +D+DDPE FP+P +EL++WA LMKRQ MA F W
Sbjct: 583 TAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLW 642
Query: 494 QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE 553
QHGEE+MAKALVACK+ ++MA+EA ++D+VDD S+EL S DFGQLAVELL+QS++QDE
Sbjct: 643 QHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDE 702
Query: 554 QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI 613
+AMKLLTYELKNWSN+TCL+LAV+++ R F+AHTC+QMLL+DMWMGRL MRKNS KVI
Sbjct: 703 TMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVI 762
Query: 614 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEP--EKPTKEKEEEDMELTAMLG 671
L IL+PP+IL LE+K K +M ++ Q+Q+ H + E + T+E E + +L
Sbjct: 763 LSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILD 822
Query: 672 RNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK 731
N G K+E E+Q K + +P+ RK Y FY+APIVKFWF TLAY+G+LML+ ++VLV+
Sbjct: 823 SNEG-----KNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQ 877
Query: 732 MERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSV 791
ME+ PS QEWIVI+YIFT IEK+REI MSE GK+ QK+KVW +Y+N++D IAI+ F +
Sbjct: 878 MEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFI 937
Query: 792 GMILRL---------QDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMM 842
G LR D GR+IYC+NII+WY+RLLD VN+ GPYVMMIGKM+
Sbjct: 938 GFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMV 997
Query: 843 IDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPC 902
+M Y V+IM +VL+SFGV R+AIL+P+E PSW LAK+I + PYWMI+GEV+A +ID
Sbjct: 998 ANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEID--- 1054
Query: 903 GQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQ 962
D I Q+ C G W+ P + A YL V I++VNLLIA FNN + +VK+ISN
Sbjct: 1055 ---VCANDSVIPQI--CGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNI 1109
Query: 963 VWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD 1022
VWK+QRY IM +HE+PVLPPPLII SH+ +F +C R +K D+ G KLF+T+
Sbjct: 1110 VWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKK-----DKTSDGPKLFLTE 1164
Query: 1023 DELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKAS 1082
++ KK+HDFEEQC+E YF EKDD+F+S ++ERIRVT ERVE M ++++EV +R + +K S
Sbjct: 1165 EDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRS 1224
Query: 1083 LQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVR 1134
LQ++D ++ L+DL L+ LT + +E++K+ + + + + + ++ +
Sbjct: 1225 LQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQ 1276
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 1265 bits (3274), Expect = 0.0
Identities = 636/1163 (54%), Positives = 843/1163 (72%), Gaps = 65/1163 (5%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R S+DTK D LLHLM KEW++ELPKL+ISVHGG+QNF + K K++F +GL+KAA TT
Sbjct: 111 YIRTSYDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETT 170
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI T G+NTGV +HVGDALK H+S S KI T+GI PWG++ENQ DLIG+DVV YQT
Sbjct: 171 GAWIITEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQT 230
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVA 181
+ NP+SKLT LNSMHSHFIL+D+GT GKYG E+KLRR LEK++SLQKI+ R QGVPVV
Sbjct: 231 LDNPLSKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCRSRQGVPVVG 290
Query: 182 LIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLL 241
L+VEGGPNVI V E ++D PV VVC+G+GRA+D+LAF HK+ + G++ ++++++
Sbjct: 291 LVVEGGPNVILSVWETVKDKDPV--VVCEGTGRAADLLAFTHKHLADEGMLRPQVKEEII 348
Query: 242 VTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA 301
IQ TF ++ Q++HLF ILMECM ++ IT+F SE QD+DLAILTALLKG N SA
Sbjct: 349 CMIQNTFNFSLKQSKHLFQILMECMVHRDCITIFDADSEEQQDLDLAILTALLKGTNLSA 408
Query: 302 PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHR 361
+QL+LA+AW+RVDIA+ I IY Q W +LEQAM DALV+DRVDFVKLLIE GV++HR
Sbjct: 409 SEQLNLAMAWDRVDIAKKHILIYEQHWKPDALEQAMSDALVMDRVDFVKLLIEYGVNLHR 468
Query: 362 FLTISRLEELYNTRHGPSNTL-YHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
FLTI RLEELYNT+ GP+NTL +HLV+DVK+ L YRI+LIDIGLV+EYL+G AYR N
Sbjct: 469 FLTIPRLEELYNTKQGPTNTLLHHLVQDVKQHTLLSGYRITLIDIGLVVEYLIGRAYRSN 528
Query: 421 YTRKRFRTLYHNLFGP--------------------------------KRDDIPLRRGRK 448
YTRK FR LY+NL+ K I L + RK
Sbjct: 529 YTRKHFRALYNNLYRKYKHQRHSSGNRNESAESTLHSQFIRTAQPYKFKEKSIVLHKSRK 588
Query: 449 TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACK 508
K +E+ V DDPE F +P+++L+VWAVLMKRQKMA+FFWQHGEEA KA++AC
Sbjct: 589 --KSKEQNVS---DDPESTGFLYPYNDLLVWAVLMKRQKMAMFFWQHGEEATVKAVIACI 643
Query: 509 LCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWS 568
L +AMAHEA E+ MVDD S+EL + S+ FGQLA++LL++++KQ+E++AM LLTYEL+NWS
Sbjct: 644 LYRAMAHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMAMTLLTYELRNWS 703
Query: 569 NATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFK 628
N+TCL+LAV+ R F++HTC+QMLLTDMWMGRL+MRKNS LK+I+ I+LPP+IL+LEFK
Sbjct: 704 NSTCLKLAVSGGLRPFVSHTCTQMLLTDMWMGRLKMRKNSWLKIIISIILPPTILTLEFK 763
Query: 629 NKDDMPYMSQAQEIHLQEKEAEEPEKPTKEK---EEEDMELTAMLGRNNGESSRKKDEEE 685
+K +M ++ Q+Q+ +++ +KE +E D+E R + E +
Sbjct: 764 SKAEMSHVPQSQDFQFMWYYSDQNASSSKESASVKEYDLE------RGHDEKLDENQHFG 817
Query: 686 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 745
++S H+ +P RK+YEFY+APIVKFWFYT+AY+ +LMLF Y VLV+M+ PS QEW+V
Sbjct: 818 LESGHQHLPWTRKVYEFYSAPIVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVQEWLVSI 877
Query: 746 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 805
YIFT IE +REI +SEPGK QKVKVW+ EYWN+T+ +AI LFS G +LR D PF +
Sbjct: 878 YIFTNAIEVVREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGFVLRWGDPPFHTA 937
Query: 806 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 865
GR+IYC++II+W+ RLLD F VN++ GPYV MI KM +M Y VIIM +VL+SFGVAR+A
Sbjct: 938 GRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLSFGVARKA 997
Query: 866 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 925
IL P E PSW LA++I + PYWMIYGEV+A +ID Q P C G+++
Sbjct: 998 ILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQ------------PSCPPGSFL 1045
Query: 926 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 985
P + A YL V I++VNLLIA FNN + +++SISN +WK+ RY+ IMT+HE+P LPPPL
Sbjct: 1046 TPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTYHEKPWLPPPL 1105
Query: 986 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1045
I+ SH+ ++ + LCC H D +E D GLKL+++ ++LKK+HDFEEQC+E+YF EK +
Sbjct: 1106 ILLSHVGLLLRRLCCHRAPH--DQEEGDVGLKLYLSKEDLKKLHDFEEQCVEKYFHEKME 1163
Query: 1046 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1105
N S +ERIRVTSERV M +L+E+NE+ +K SL ++D ++ L+DL L+
Sbjct: 1164 DVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSALTVDTLK 1223
Query: 1106 RLTGLERAESNK--IRSRTSSDC 1126
L+ ++ + ++ + R S C
Sbjct: 1224 VLSAVDTLQEDEALLAKRKHSTC 1246
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 1207 bits (3122), Expect = 0.0
Identities = 672/1204 (55%), Positives = 818/1204 (67%), Gaps = 112/1204 (9%)
Query: 330 VGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV 389
V +LEQAMLDALVLDRVDFVKLLIENGV+M FLTI RLEELYNTR GP NTL+ LVRDV
Sbjct: 458 VNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDV 517
Query: 390 KKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------- 438
KK NLPPDY ISLIDIGLV+EYLMGGAYRCNYTRK FRTLY+NLFGPKR
Sbjct: 518 KKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKALKLLGMED 577
Query: 439 DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEE 498
D+ P + +K KK+EEE+DID+DDP ++ F +PFHELMVWAVLMKRQKMA+F WQ GEE
Sbjct: 578 DEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEE 637
Query: 499 AMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMK 558
+MAKALVACKL KAMAHE+SE+D+VDDISQ+L++NS+DFGQLA+ELLDQSYK DEQ+AMK
Sbjct: 638 SMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMK 697
Query: 559 LLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILL 618
LLTYELKNWSN+TCL+LAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKN GLKVI+GILL
Sbjct: 698 LLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILL 757
Query: 619 PPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESS 678
PP+IL LEF+ DD Y + KE E+ KEKEEE+ + A G S
Sbjct: 758 PPTILFLEFRTYDDFSYQTS--------KENEDG----KEKEEENTDANADAG------S 799
Query: 679 RKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST 738
RK DEE K R IP+G KI EFYNAPIVKFWFYT++Y+GYL+LFNY++LV+M+ WPS
Sbjct: 800 RKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSL 859
Query: 739 QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ 798
QEWIVISYI +L +EK+REILMSEPGKL QK+KVWLQEYWN+TDL+AI F +G ILRLQ
Sbjct: 860 QEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQ 919
Query: 799 DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMS 858
+QP+ GRVIYCV+II+WYIR+LDIFGVNKYLGPYVMMIGKMMIDM+YFV+IMLVVLMS
Sbjct: 920 NQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMS 979
Query: 859 FGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID-------PPCGQNETREDG 911
FGVARQAIL P E+PSWKLA+NIFYMPYWMIYGEVFADQID PPCG+N E+G
Sbjct: 980 FGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEG 1039
Query: 912 KIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 971
K +LPPC GAW+ PA+MACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL
Sbjct: 1040 K--RLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 1097
Query: 972 IMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR-KHESDPDERDYGLKLFITDDELKKVHD 1030
IMTFH+RPVLPPP+II SH+ +I L R R K E D +ERD GLKLF++D+ELK++H+
Sbjct: 1098 IMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHE 1157
Query: 1031 FEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRL 1090
FEEQC++E+FREK+D SS+DERIRVTSERVENMSMRLEE+NERE MK SLQTVD+RL
Sbjct: 1158 FEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMKTSLQTVDLRL 1217
Query: 1091 AQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNT----- 1145
AQLE+L RM ALE L G++R++ + RSR SS+C +A Y++RQSS NS +G +
Sbjct: 1218 AQLEELSNRMVNALENLAGIDRSDLIQARSRASSEC-EATYLLRQSSINSADGYSLYRYH 1276
Query: 1146 FKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRAT 1205
F +E + E+T TSP R ++ SF KD + E SLH +
Sbjct: 1277 FNGEELL---FEDTSLSTSPGTGVRKKTCSFRIKEEKD-----VKTHLVPECQNSLHLSL 1328
Query: 1206 SSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGE 1265
+ + A PD H +D L N+ E
Sbjct: 1329 GTSTSA---------------TPDGS----------------HLAVDDLKNA-------E 1350
Query: 1266 PSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDS 1325
S P + T + + S S++ D+ +S + E N
Sbjct: 1351 ESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNTQLTVETTN---I 1407
Query: 1326 EPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSIT 1385
E + + +E +K +RY + +KS SF++S R V EY+SIT
Sbjct: 1408 EGTISYPLEETKITRYFPDE--TINACKTMKSRSFVYSRGRKLVGGVNQDV---EYSSIT 1462
Query: 1386 D---CIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGR 1442
D + +C + P + E + + + + EA R
Sbjct: 1463 DQQLTTEWQCQVQKITRSHSTDIP-----YIVSEAAVQAEHKEQFADMQDEHHVAEAIPR 1517
Query: 1443 RATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRN 1502
++++ + + E LS K ++ + + + + H R SI KLDR +
Sbjct: 1518 IPRLSLTITDRNGMENLLS-----VKPDQTLGFPSLRSKSLHGHPRNVKSIQGKLDRSGH 1572
Query: 1503 TASL 1506
+S+
Sbjct: 1573 ASSV 1576
Score = 572 bits (1474), Expect = e-162
Identities = 274/334 (82%), Positives = 309/334 (92%), Gaps = 1/334 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MY+RVS+DTKPD LLHLM K+WQLELPKLLISVHGGLQNFE+QPKLKQVFGKGLIKAAMT
Sbjct: 71 MYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMT 130
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGV+TGVI HVGDALKDH+SKSRG++C IGIAPWGIVEN+EDL+G+DV R YQ
Sbjct: 131 TGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQ 190
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNP+SKL+VLN+ H+HFILADNGT GKYGAEVKLRR LEKHISLQKINTR+GQGVP+V
Sbjct: 191 TMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLV 250
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
L+VEGGPNV+SIVLEYL++ PP+PVV+CDGSGRASDIL+F HKY EEGG+INESLR+QL
Sbjct: 251 GLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEEGGIINESLREQL 310
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTF Y + Q+ LF I+MECMKKKEL+TVFRMGSEG QDI++AILTALLKG N S
Sbjct: 311 LVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNVS 370
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQW-PVGSL 333
APDQLSLALAWNRVDIARSQIF++G W P+GSL
Sbjct: 371 APDQLSLALAWNRVDIARSQIFVFGPHWPPLGSL 404
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 528 bits (1361), Expect = e-149
Identities = 371/1151 (32%), Positives = 593/1151 (51%), Gaps = 131/1151 (11%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVRVS DT ++ HLMT+ W L++P LLISV GG +NF ++P+LK +F +GL+K A TT
Sbjct: 142 YVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTT 201
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKS---RGKICTIGIAPWGIVENQEDLIGRDVVRP 118
GAWI TGG +TGV++ VG+A++D + S G++ TIG+A WG V +E LI P
Sbjct: 202 GAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFP 261
Query: 119 --YQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQ-KINTRIGQ 175
Y + LT L+S HSHFIL D+GT G+YG E+ LR +LEK IS Q K +
Sbjct: 262 AEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAI 321
Query: 176 GVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINES 235
+P+V +++EGGP + + T P VV +GSGR +D++A I+
Sbjct: 322 KIPIVCVVLEGGPGTLHTIDN--ATTNGTPCVVVEGSGRVADVIAQVANLPVSDITIS-L 378
Query: 236 LRDQLLVTIQKTF-TYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALL 294
++ +L V Q+ F T+T ++ + + +++++L+TVFR G +G QD+D+AIL ALL
Sbjct: 379 IQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALL 438
Query: 295 KGANASA-------PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVD 347
K + + QL LA+AWNRVDIARS+IF+ QW L M AL+ ++ +
Sbjct: 439 KASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPE 498
Query: 348 FVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYH------LVRDVKKGNLPPDY-RI 400
FVKL +ENGV + F+T L LY + L+H LV D ++ P R+
Sbjct: 499 FVKLFLENGVQLKEFVTWDTLLYLYENLD--PSCLFHSKLQKVLVEDPERPACAPAAPRL 556
Query: 401 SLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRG--RKTTKKREEEVD 458
+ + V+ L+G + Y R R L + ++ R K+ V
Sbjct: 557 QMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVT 616
Query: 459 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 518
+D P +L++WA++ R+++A W ++ +A AL K+ K ++ E
Sbjct: 617 FTMD---------PIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEE 667
Query: 519 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 578
+ D S+E+ + ++ A+ + + Y++DE+ A KLLT + W TCLQLA+
Sbjct: 668 DTDS----SEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALE 723
Query: 579 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGL-KVILGILLPPSILSLEFKNKDDMPYMS 637
AK F++H Q LT +W G+L + ++GL +V L +L P +
Sbjct: 724 AKDMKFVSHGGIQAFLTKVWWGQLSV--DNGLWRVTLCMLAFPLL--------------- 766
Query: 638 QAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR 697
LT ++ S R+K ++V +
Sbjct: 767 ----------------------------LTGLI------SFREKRLQDVGTP------AA 786
Query: 698 KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMRE 757
+ F+ AP+V F L+Y +L LF Y+++V + PS E + ++F+L E+MR+
Sbjct: 787 RARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQ 846
Query: 758 ILMSEPGK--LLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 815
L +P + L++K ++ ++WN D+ AILLF G+ RL GRVI ++ I
Sbjct: 847 -LFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYP-GRVILSLDFI 904
Query: 816 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 875
+ +RL+ IF ++K LGP ++++ +MM D+ +F+ ++ V ++SFGVA+QAIL NE
Sbjct: 905 LFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVD 964
Query: 876 KLAKNIFYMPYWMIYGEV--FADQID---PPCGQNETR-------EDGKIIQLPPCKTGA 923
L + Y Y I+G++ + D ++ C N T E Q P
Sbjct: 965 WLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPE-- 1022
Query: 924 WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP 983
W+ ++ YLL NILL+NLLIA+FN TF +V+ ++Q+WKFQR+ LI +H RP PP
Sbjct: 1023 WLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPP 1082
Query: 984 PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK 1043
P I+ SH+ + + + + P +R LK + +E + +E E Y + +
Sbjct: 1083 PFILLSHLQLFIKRVVLK------TPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNR 1136
Query: 1044 DDRFNSSNDERIRVTSERVENMSMRLE-EVNEREHSMKASLQTVDIRLAQLEDLIGRMAT 1102
+ +++I S +V+ M L+ + +R SM+ RLA LE+ + + A
Sbjct: 1137 QFQQKQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQ-------RLASLEEQVAQTAR 1189
Query: 1103 ALERLTGLERA 1113
AL + RA
Sbjct: 1190 ALHWIVRTLRA 1200
>gi|21314671 transient receptor potential cation channel, subfamily M,
member 4 [Homo sapiens]
Length = 1214
Score = 474 bits (1219), Expect = e-133
Identities = 346/1154 (29%), Positives = 586/1154 (50%), Gaps = 97/1154 (8%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
++R+S T P + L+T+ W P L++SV GG LQ L+ + +GL++AA +T
Sbjct: 90 FLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQST 149
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRG--KICTIGIAPWGIVENQEDLIGRDVVRP- 118
GAWI TGG++TG+ RHVG A++DH S G K+ +G+APWG+V N++ LI P
Sbjct: 150 GAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPA 209
Query: 119 -YQTMSNPMSKLTV-LNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-IGQ 175
Y+ +P + L+ +S F L D+GT G G E + R +LE +IS QK G
Sbjct: 210 RYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGI 269
Query: 176 GVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYS---EEGGLI 232
+PV+ L+++G +++ + + +P ++ GSG A+D LA + + GG
Sbjct: 270 DIPVLLLLIDGDEKMLTRIENATQ--AQLPCLLVAGSGGAADCLAETLEDTLAPGSGGAR 327
Query: 233 NESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTA 292
RD++ + F + + + L + M +KEL+TV+ +G ++ + +L A
Sbjct: 328 QGEARDRI-----RRF-FPKGDLEVLQAQVERIMTRKELLTVYS-SEDGSEEFETIVLKA 380
Query: 293 LLKGANASAP----DQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF 348
L+K +S D+L LA+AWNRVDIA+S++F QW LE +++DAL+ DR +F
Sbjct: 381 LVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEF 440
Query: 349 VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK---GNLPPDYR-----I 400
V+LLI +G+S+ FLT RL +LY+ PSN+L + D G P + +
Sbjct: 441 VRLLISHGLSLGHFLTPMRLAQLYSA--APSNSLIRNLLDQASHSAGTKAPALKGGAAEL 498
Query: 401 SLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDID 460
D+G V+ L+G Y G D P + ++ ++
Sbjct: 499 RPPDVGHVLRMLLGKMCAPRYPS-----------GGAWDPHPGQGFGESMYLLSDKATSP 547
Query: 461 LD-DPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH---E 516
L D + P+ +L++WA+L+ R +MA++FW+ G A++ AL AC L + MA +
Sbjct: 548 LSLDAGLGQAPWS--DLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPD 605
Query: 517 ASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLA 576
A E D++ + F + V+L + Y+ E A +LL W +ATCLQLA
Sbjct: 606 AEEAARRKDLAFK-------FEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLA 658
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILS--LEFKNKDDMP 634
+ A R F A Q LLT W G + ++L PP I + + F+ ++ P
Sbjct: 659 MQADARAFFAQDGVQSLLTQKWWGDMASTTPIWA-LVLAFFCPPLIYTRLITFRKSEEEP 717
Query: 635 YMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIP 694
+ + E P E+ + + GR R +
Sbjct: 718 TREELEFDMDSVINGEGPVGTADPAEKTPLGVPRQSGRPGCCGGRCGGRRCL-------- 769
Query: 695 LGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWP-STQEWIVISYIFTLGIE 753
R+ + F+ AP+ F ++Y+ +L+LF+ ++LV + P + E ++ + FTL E
Sbjct: 770 --RRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCE 827
Query: 754 KMREILMSEPGKLL------------QKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQP 801
++R+ L G L Q+++++L + WN DL+A+ F +G+ RL
Sbjct: 828 ELRQGLSGGGGSLASGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGL 887
Query: 802 FRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGV 861
+ GR + C++ + + +RLL IF VNK LGP ++++ KMM D+ +F+ + V L+++GV
Sbjct: 888 YHL-GRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGV 946
Query: 862 ARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQ--NETREDGKIIQLPPC 919
A + +L P + + + +FY PY I+G++ + +D + N + E G P
Sbjct: 947 ATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGA 1006
Query: 920 KTGA-------WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLI 972
+ G W+V ++ +LLVANILLVNLLIA+F+ TF +V+ S+ WK QRY+LI
Sbjct: 1007 QAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLI 1066
Query: 973 MTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFE 1032
FH RP L PP I+ SH+ ++ + LC R R + ++ +++++ + +K+ +E
Sbjct: 1067 REFHSRPALAPPFIVISHLRLLLRQLCRRPRSPQPSSPALEH-FRVYLSKEAERKLLTWE 1125
Query: 1033 EQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQ 1092
E + + S+ ER++ TS++V+ +L + E E +K ++ + Q
Sbjct: 1126 SVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLK----VLEREVQQ 1181
Query: 1093 LEDLIGRMATALER 1106
++G +A AL R
Sbjct: 1182 CSRVLGWVAEALSR 1195
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 466 bits (1198), Expect = e-130
Identities = 344/1138 (30%), Positives = 565/1138 (49%), Gaps = 133/1138 (11%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
+VRV P +L L+ EW L P L++S+ G Q F ++ L+ V KGL+KAA +T
Sbjct: 40 FVRVPSGVAPSVLFDLLLAEWHLPAPNLVVSLVGEEQPFAMKSWLRDVLRKGLVKAAQST 99
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHA---SKSRGKICTIGIAPWGIV-------ENQEDLI 111
GAWI T + G+ RHVG A++DH+ + ++ ++ +G+A G V E QED
Sbjct: 100 GAWILTSALRVGLARHVGQAVRDHSLASTSTKVRVVAVGMASLGRVLHRRILEEAQEDF- 158
Query: 112 GRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINT 171
V + L L+S SHFIL + G GK +LR +LEKHIS Q
Sbjct: 159 ---PVHYPEDDGGSQGPLCSLDSNLSHFILVEPGPPGKGDGLTELRLRLEKHISEQ---- 211
Query: 172 RIGQG------VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKY 225
R G G +PV+ L+V G PN + + + P ++V GSG +D+LA
Sbjct: 212 RAGYGGTGSIEIPVLCLLVNGDPNTLERISRAVEQAAPWLILV--GSGGIADVLA----- 264
Query: 226 SEEGGLINESLRDQLLV--TIQKTFTYTRTQAQHLFI--------ILMECMKKKELITVF 275
L+N+ LLV +K F + ++H +L + L+TV+
Sbjct: 265 ----ALVNQP---HLLVPKVAEKQFK-EKFPSKHFSWEDIVRWTKLLQNITSHQHLLTVY 316
Query: 276 RMGSEGHQDIDLAILTALLKGANASAP------DQLSLALAWNRVDIARSQIFIYGQQWP 329
EG +++D IL AL+K + + D+L LA+AW+RVDIA+S+IF +W
Sbjct: 317 DFEQEGSEELDTVILKALVKACKSHSQEPQDYLDELKLAVAWDRVDIAKSEIFNGDVEWK 376
Query: 330 VGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV 389
LE+ M+DALV ++ +FV+L ++NG + FLT RL+ELY + S L R
Sbjct: 377 SCDLEEVMVDALVSNKPEFVRLFVDNGADVADFLTYGRLQELYRSVSRKSLLFDLLQRKQ 436
Query: 390 KKGNL----------------PPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNL 433
++ L PP + SL ++ V++ + A R Y
Sbjct: 437 EEARLTLAGLGTQQAREPPAGPPAF--SLHEVSRVLKDFLQDACRGFY------------ 482
Query: 434 FGPKRDDIP--LRRGRKTTKKRE--EEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMA 489
+D P RR K KR ++ +DL+ N P+ +L +WAVL R +MA
Sbjct: 483 ----QDGRPGDRRRAEKGPAKRPTGQKWLLDLNQKSEN----PWRDLFLWAVLQNRHEMA 534
Query: 490 LFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSY 549
+FW G+E +A AL ACK+ K M+H +E + + + +LA++L + Y
Sbjct: 535 TYFWAMGQEGVAAALAACKILKEMSHLETEAEAARATREA------KYERLALDLFSECY 588
Query: 550 KQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSG 609
E A LL + WS TCL LA A + F AH Q LT +W G M +
Sbjct: 589 SNSEARAFALLVRRNRCWSKTTCLHLATEADAKAFFAHDGVQAFLTRIWWGD--MAAGTP 646
Query: 610 LKVILGILLPPSILSLEFKN-KDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTA 668
+ +LG L P+++ ++ P + ++ LQ+ ++ + EK + +E
Sbjct: 647 ILRLLGAFLCPALVYTNLITFSEEAPLRTGLED--LQDLDSLDTEKSPLYGLQSRVEELV 704
Query: 669 MLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIV 728
R G+ R + L + +F+ AP+ F + Y +L LF Y++
Sbjct: 705 EAPRAQGDRGP-----------RAVFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFTYVL 753
Query: 729 LVKME---RWPSTQEWIVISYIFTLGIEKMRE-ILMSEPGKLLQKVKVWLQEYWNVTDLI 784
LV + PS E + ++FTL +E++R+ E L++K +++ + WN D++
Sbjct: 754 LVDFRPPPQGPSGPEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVGDNWNKCDMV 813
Query: 785 AILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMID 844
AI LF VG+ R+ F + GR + ++ + + +RL+ IF ++K LGP ++++ +MM D
Sbjct: 814 AIFLFIVGVTCRMLPSAFEA-GRTVLAMDFMVFTLRLIHIFAIHKQLGPKIIVVERMMKD 872
Query: 845 MMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQ 904
+ +F+ + V L+++GV QA+L P++ + + + Y PY I+G++ D+ID
Sbjct: 873 VFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDE-ARV 931
Query: 905 NETREDGKIIQLPPCKT--GAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQ 962
N + + P C + W+V ++ +LLV N+LL+NLLIA+F+ TF V+ ++
Sbjct: 932 NCSTHPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADM 991
Query: 963 VWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITD 1022
WKFQRY LI+ +HERP L PP I+ SH+++ + + + +H+ + ERD + D
Sbjct: 992 FWKFQRYNLIVEYHERPALAPPFILLSHLSLTLRRVFKKEAEHKREHLERD------LPD 1045
Query: 1023 DELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK 1080
+KV +E E + + + R S E +R T+ RV+ ++ L + E+E +K
Sbjct: 1046 PLDQKVVTWETVQKENFLSKMEKRRRDSEGEVLRKTAHRVDFIAKYLGGLREQEKRIK 1103
>gi|45935368 transient receptor potential cation channel, subfamily
M, member 3 isoform h [Homo sapiens]
Length = 230
Score = 464 bits (1194), Expect = e-130
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 230
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 230
>gi|55953096 transient receptor potential cation channel, subfamily
M, member 3 isoform c [Homo sapiens]
Length = 255
Score = 450 bits (1158), Expect = e-126
Identities = 230/255 (90%), Positives = 230/255 (90%), Gaps = 25/255 (9%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGG 230
SDILAFGHKYSEEGG
Sbjct: 241 SDILAFGHKYSEEGG 255
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 286 bits (731), Expect = 1e-76
Identities = 194/638 (30%), Positives = 322/638 (50%), Gaps = 66/638 (10%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R+S DT ++L L+T+ W L+ P L+ISV GG +NF L+P+++++F + LI A +
Sbjct: 117 YIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSR-LIYIAQSK 175
Query: 62 GAWIFTGGVNTGVIRHVGDALKDH--ASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPY 119
GAWI TGG + G+++++G+ ++D+ + S I IGIA WG+V N++ LI Y
Sbjct: 176 GAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGY 235
Query: 120 QTMSNPMSKLT-----VLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI-NTRI 173
M T +L++ H+H +L DNG G E KLR QLEK+IS + I ++
Sbjct: 236 FLAQYLMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQDSNY 295
Query: 174 GQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLIN 233
G +P+V GG + + +++ +P VV +GSG+ +D++A E L +
Sbjct: 296 GGKIPIVCFAQGGGKETLKAINTSIKNK--IPCVVVEGSGQIADVIA--SLVEVEDALTS 351
Query: 234 ESLRDQLLVTIQKTFTYTRTQAQHLFII-LMECMKKKELITVFRMGSEGHQDIDLAILTA 292
+++++L+ + +T + + +I L E ++ L+TV +M G + + AI A
Sbjct: 352 SAVKEKLVRFLPRTVSRLPEEETESWIKWLKEILECSHLLTVIKMEEAGDEIVSNAISYA 411
Query: 293 LLKGANASAPD------QLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRV 346
L K + S D QL L L WN++D+A +IF ++W L++ M AL+ DR
Sbjct: 412 LYKAFSTSEQDKDNWNGQLKLLLEWNQLDLANDEIFTNDRRWESADLQEVMFTALIKDRP 471
Query: 347 DFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIG 406
FV+L +ENG+++ +FLT L EL++ S +Y ++ K S D
Sbjct: 472 KFVRLFLENGLNLRKFLTHDVLTELFSNHF--STLVYRNLQIAKN---------SYNDAL 520
Query: 407 LVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDD--P 464
L + + +R R RK + +E+DI+L D P
Sbjct: 521 LTFVWKLVANFR-------------------------RGFRKEDRNGRDEMDIELHDVSP 555
Query: 465 EINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVD 524
H P L +WA+L +++++ W+ AL A KL K +A ++ +
Sbjct: 556 ITRH---PLQALFIWAILQNKKELSKVIWEQTRGCTLAALGASKLLKTLAKVKNDINAAG 612
Query: 525 DISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDF 584
+ S+EL + ++ AVEL + Y DE LA +LL Y + W + CL+LAV A + F
Sbjct: 613 E-SEEL---ANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHF 668
Query: 585 IAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSI 622
IA Q L+ W G + R K+IL + + P +
Sbjct: 669 IAQPGVQNFLSKQWYGEI-SRDTKNWKIILCLFIIPLV 705
Score = 172 bits (435), Expect = 3e-42
Identities = 109/370 (29%), Positives = 193/370 (52%), Gaps = 32/370 (8%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMS 761
F+ +P V F + + YI +L+LF Y++L+ P E ++ S +F L +++R+ ++
Sbjct: 730 FFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVN 789
Query: 762 EPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRS--DGRVIYCVNIIYWYI 819
+ + WNV D + + F G++ RL S GRVI+C++ I + +
Sbjct: 790 GVN--------YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTL 841
Query: 820 RLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAK 879
RL+ IF V++ LGP ++M+ +M+ID+ +F+ + V +++FGVARQ IL NE+ + +
Sbjct: 842 RLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFR 901
Query: 880 NIFYMPYWMIYGEVFADQID------PPCGQNETREDGKIIQLPP---CKTGAWIVPAIM 930
++ Y PY ++G+V +D +D C ++L + WI ++
Sbjct: 902 SVIYEPYLAMFGQVPSD-VDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLV 960
Query: 931 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 990
Y+L NILLVNLL+A+F T V+ ++QVWKFQRY L+ + R +P P I+F++
Sbjct: 961 CIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAY 1020
Query: 991 MTMIFQ---HLCCRWRKHES------DPDERDYGLKLFITDDELKKVHDFEEQCIEEY-- 1039
M+ + CC+ + ES + D + + ++ L K++ EE
Sbjct: 1021 FYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRH 1080
Query: 1040 -FREKDDRFN 1048
FR+ D + N
Sbjct: 1081 RFRQLDTKLN 1090
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
Query: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1016
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
Query: 1017 KLFITDDELKKVHDFEE 1033
D L++ H ++E
Sbjct: 519 IGRRAADNLRRHHQYQE 535
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1016
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1017 KLFITDDELKKVHDFEE 1033
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 524 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 576
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 619
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1016
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1017 KLFITDDELKKVHDFEE 1033
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 524 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 576
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 619
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|7706747 transient receptor potential cation channel, subfamily C,
member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1016
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1017 KLFITDDELKKVHDFEE 1033
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 524 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 576
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 619
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 78.2 bits (191), Expect = 6e-14
Identities = 71/343 (20%), Positives = 150/343 (43%), Gaps = 67/343 (19%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLC 999
KF R +L M++ E V+P P ++ + I+ HLC
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLC 678
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 524 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 576
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 619
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|6912736 transient receptor potential cation channel, subfamily C,
member 5 [Homo sapiens]
Length = 973
Score = 71.2 bits (173), Expect = 7e-12
Identities = 76/360 (21%), Positives = 154/360 (42%), Gaps = 77/360 (21%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L + +IV + P+ EW+++ ++ +
Sbjct: 359 FIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGE 418
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGR------- 807
++E M + G ++ ++WN+ D L+ + L++ + R
Sbjct: 419 IKE--MWDGG-----FTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEM 471
Query: 808 --------VIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ ++ I +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 472 WHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 531
Query: 860 GVARQAILF---------PNEEPSWKLAK--NIF-------YMPYWMIYG--EVFADQID 899
+ F PN + K N F +W ++G ++ +
Sbjct: 532 ANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 900 PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 959
++E E ++ + Y +++ ++L+N+LIA+ NN++ +
Sbjct: 592 ---ARHEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 634
Query: 960 SNQVWKFQRYQLIMT-FHERPVLPPPLII------FSHMTMIFQHLCCRWRKHESDPDER 1012
++ WKF R +L M+ F E LPPP I F ++ F + C R DPD R
Sbjct: 635 ADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKR----DPDGR 690
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 3e-09
Identities = 60/310 (19%), Positives = 135/310 (43%), Gaps = 60/310 (19%)
Query: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTF-FEVKSISNQV 963
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ +
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRAADNL 635
Query: 964 WKFQRYQLIM 973
+ +YQ +M
Sbjct: 636 RRHHQYQEVM 645
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 524 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 576
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 577 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 619
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 57.0 bits (136), Expect = 1e-07
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 798 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 853
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
Query: 854 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 907
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
Query: 908 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 967
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
Query: 968 RYQLIMT-FHERPVLPPP 984
R +L ++ F E LP P
Sbjct: 691 RAKLWLSYFDEGRTLPAP 708
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 769 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 823
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 569 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 628
Query: 824 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 879
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 629 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 688
Query: 880 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 939
F +W I+G + + D K I+ I + Y + +
Sbjct: 689 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 733
Query: 940 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 984
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 734 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 779
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 693 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 751
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 641 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 700
Query: 752 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 794
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 701 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 743
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 769 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 823
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 496 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 555
Query: 824 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 879
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 556 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 615
Query: 880 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 939
F +W I+G + + D K I+ I + Y + +
Sbjct: 616 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 660
Query: 940 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 984
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 661 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 706
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 693 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 751
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 568 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 627
Query: 752 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 794
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 628 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 670
>gi|5730102 transient receptor potential cation channel, subfamily C,
member 6 [Homo sapiens]
Length = 931
Score = 54.3 bits (129), Expect = 9e-07
Identities = 70/349 (20%), Positives = 133/349 (38%), Gaps = 89/349 (25%)
Query: 737 STQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR 796
S E ++IS++ + + +EI P K +L E WN+ D + +F+ I R
Sbjct: 492 SWMEMLIISWVIGMIWAECKEIWTQGP-------KEYLFELWNMLDFGMLAIFAASFIAR 544
Query: 797 LQ-------------------------------------------DQPFRSDGRVIYCVN 813
D S+G +Y +
Sbjct: 545 FMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEG--LYAIA 602
Query: 814 IIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGV-----------A 862
++ + R+ I N+ GP + +G+ + D+ F++I ++V ++F + A
Sbjct: 603 VVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA 662
Query: 863 RQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTG 922
+Q F E S+K +W I+G + G ++
Sbjct: 663 KQNEAFTTVEESFKTL-------FWAIFGLSEVKSVVINYNHKFIENIGYVLY------- 708
Query: 923 AWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVL 981
Y + I+L+N+LIA+ N++F E++ ++ WKF R +L + F E L
Sbjct: 709 --------GVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTL 760
Query: 982 PPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHD 1030
P P + +F +L + +K S+ + K F D E+ K+++
Sbjct: 761 PVPFNLVPSPKSLF-YLLLKLKKWISELFQGH--KKGFQEDAEMNKINE 806
Score = 36.6 bits (83), Expect = 0.19
Identities = 21/103 (20%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 693 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM-ERWPSTQEWIVISYIFTLG 751
I LGR + + + ++ + IG L++Y + K E + + +E + G
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFG 684
Query: 752 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 794
+ +++ ++++ K ++ + L +NVT +I +L + MI
Sbjct: 685 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMI 727
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 52.8 bits (125), Expect = 3e-06
Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 831 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 889
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P +L Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPE-ELGHFYDYPMALFS 532
Query: 890 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 949
E+F ID P N + LP ++ A + ++A +L++NLLIA+
Sbjct: 533 TFELFLTIIDGPANYN--------VDLP------FMYSITYAAFAIIATLLMLNLLIAMM 578
Query: 950 NNTFFEVKSISNQVWKFQ 967
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAHERDELWRAQ 596
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 831 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 889
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P+ L + Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPT-SLGQFYDYPMALFT 532
Query: 890 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 949
E+F ID P + + LP ++ + + ++A +L++NL IA+
Sbjct: 533 TFELFLTVIDAPANYD--------VDLP------FMFSIVNFAFAIIATLLMLNLFIAMM 578
Query: 950 NNTFFEVKSISNQVWKFQ 967
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAQERDELWRAQ 596
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 704 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 761
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
Query: 762 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 805
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
Query: 806 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 865
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
Query: 866 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 906
+ + ++E K IF + +W I+ E
Sbjct: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
Query: 907 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 966
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
Query: 967 QRYQLIMT-FHERPVLPPPLII 987
R +L ++ F ++ LPPP I
Sbjct: 629 ARAKLWLSYFDDKCTLPPPFNI 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,724,663
Number of Sequences: 37866
Number of extensions: 2716929
Number of successful extensions: 13498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 12743
Number of HSP's gapped (non-prelim): 684
length of query: 1544
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1429
effective length of database: 13,892,928
effective search space: 19852994112
effective search space used: 19852994112
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.