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Search of human proteins with 154091316
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154091316 transient receptor potential cation channel,
subfamily M, member 3 isoform e [Homo sapiens]
(1556 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154091316 transient receptor potential cation channel, subfam... 3131 0.0
gi|154091312 transient receptor potential cation channel, subfam... 3123 0.0
gi|154091318 transient receptor potential cation channel, subfam... 3093 0.0
gi|154091320 transient receptor potential cation channel, subfam... 3085 0.0
gi|154091314 transient receptor potential cation channel, subfam... 3085 0.0
gi|154091310 transient receptor potential cation channel, subfam... 3079 0.0
gi|154091308 transient receptor potential cation channel, subfam... 3071 0.0
gi|148612863 transient receptor potential cation channel, subfam... 1359 0.0
gi|18921093 transient receptor potential cation channel, subfami... 1257 0.0
gi|94538366 transient receptor potential cation channel, subfami... 1198 0.0
gi|4507689 transient receptor potential cation channel, subfamil... 525 e-148
gi|21314671 transient receptor potential cation channel, subfami... 473 e-133
gi|11225266 transient receptor potential cation channel, subfami... 466 e-131
gi|45935368 transient receptor potential cation channel, subfami... 464 e-130
gi|55953096 transient receptor potential cation channel, subfami... 450 e-126
gi|109689695 transient receptor potential cation channel, subfam... 283 9e-76
gi|209863032 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863030 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863026 transient receptor potential cation channel, subfam... 80 1e-14
gi|7706747 transient receptor potential cation channel, subfamil... 80 1e-14
gi|209863024 transient receptor potential cation channel, subfam... 78 6e-14
gi|6912736 transient receptor potential cation channel, subfamil... 71 7e-12
gi|209863028 transient receptor potential cation channel, subfam... 62 3e-09
gi|9966865 transient receptor potential cation channel, subfamil... 57 1e-07
gi|194733735 transient receptor potential cation channel, subfam... 57 2e-07
gi|4507687 transient receptor potential cation channel, subfamil... 57 2e-07
gi|5730102 transient receptor potential cation channel, subfamil... 54 9e-07
gi|21314682 transient receptor potential cation channel, subfami... 53 3e-06
gi|17505200 transient receptor potential cation channel, subfami... 50 1e-05
gi|4507685 transient receptor potential cation channel, subfamil... 47 2e-04
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 3131 bits (8117), Expect = 0.0
Identities = 1556/1556 (100%), Positives = 1556/1556 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 480
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 480
Query: 481 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 540
FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ
Sbjct: 481 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 540
Query: 541 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 600
ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT
Sbjct: 541 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 600
Query: 601 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 660
CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE
Sbjct: 601 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 660
Query: 661 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 720
AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV
Sbjct: 661 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 720
Query: 721 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 780
KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ
Sbjct: 721 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 780
Query: 781 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 840
KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN
Sbjct: 781 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 840
Query: 841 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 900
KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM
Sbjct: 841 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 900
Query: 901 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 960
IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV
Sbjct: 901 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 960
Query: 961 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1020
FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD
Sbjct: 961 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1020
Query: 1021 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1080
PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR
Sbjct: 1021 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1080
Query: 1081 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1140
LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD
Sbjct: 1081 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1140
Query: 1141 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1200
AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE
Sbjct: 1141 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1200
Query: 1201 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1260
KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH
Sbjct: 1201 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1260
Query: 1261 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1320
CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS
Sbjct: 1261 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1320
Query: 1321 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1380
FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY
Sbjct: 1321 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1380
Query: 1381 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1440
YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS
Sbjct: 1381 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1440
Query: 1441 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1500
HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR
Sbjct: 1441 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1500
Query: 1501 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1556
KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1501 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1556
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 3123 bits (8096), Expect = 0.0
Identities = 1556/1566 (99%), Positives = 1556/1566 (99%), Gaps = 10/1566 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVD 470
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVD
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 480
Query: 471 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 530
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 481 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 540
Query: 531 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 590
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 541 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 600
Query: 591 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 650
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 601 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 660
Query: 651 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 710
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 661 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 720
Query: 711 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 770
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 721 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 780
Query: 771 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 830
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 781 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 840
Query: 831 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 890
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 841 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 900
Query: 891 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 950
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 901 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 960
Query: 951 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1010
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 961 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1020
Query: 1011 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1070
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1021 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1080
Query: 1071 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1130
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1081 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1140
Query: 1131 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1190
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1141 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1200
Query: 1191 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1250
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1201 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1260
Query: 1251 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1310
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1261 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1320
Query: 1311 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1370
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1321 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1380
Query: 1371 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1430
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1381 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1440
Query: 1431 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1490
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1441 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1500
Query: 1491 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1550
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1501 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1560
Query: 1551 FESKHN 1556
FESKHN
Sbjct: 1561 FESKHN 1566
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 3093 bits (8019), Expect = 0.0
Identities = 1544/1556 (99%), Positives = 1544/1556 (99%), Gaps = 12/1556 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 408
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 480
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH
Sbjct: 409 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINH 468
Query: 481 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 540
FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ
Sbjct: 469 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 528
Query: 541 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 600
ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT
Sbjct: 529 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 588
Query: 601 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 660
CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE
Sbjct: 589 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 648
Query: 661 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 720
AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV
Sbjct: 649 AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIV 708
Query: 721 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 780
KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ
Sbjct: 709 KFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQ 768
Query: 781 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 840
KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN
Sbjct: 769 KVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVN 828
Query: 841 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 900
KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM
Sbjct: 829 KYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWM 888
Query: 901 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 960
IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV
Sbjct: 889 IYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAV 948
Query: 961 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1020
FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD
Sbjct: 949 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1008
Query: 1021 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1080
PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR
Sbjct: 1009 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1068
Query: 1081 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1140
LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD
Sbjct: 1069 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTD 1128
Query: 1141 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1200
AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE
Sbjct: 1129 AAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIE 1188
Query: 1201 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1260
KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH
Sbjct: 1189 KLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELH 1248
Query: 1261 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1320
CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS
Sbjct: 1249 CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRS 1308
Query: 1321 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1380
FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY
Sbjct: 1309 FSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSY 1368
Query: 1381 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1440
YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS
Sbjct: 1369 YANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELS 1428
Query: 1441 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1500
HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR
Sbjct: 1429 HPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTR 1488
Query: 1501 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1556
KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1489 KSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 3085 bits (7998), Expect = 0.0
Identities = 1544/1566 (98%), Positives = 1544/1566 (98%), Gaps = 22/1566 (1%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 408
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVD 470
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVD
Sbjct: 409 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 468
Query: 471 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 530
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 469 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 528
Query: 531 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 590
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 529 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 588
Query: 591 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 650
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 589 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 648
Query: 651 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 710
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 649 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 708
Query: 711 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 770
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 709 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 768
Query: 771 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 830
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 769 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 828
Query: 831 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 890
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 829 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 888
Query: 891 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 950
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 889 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 948
Query: 951 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1010
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 949 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1008
Query: 1011 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1070
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1009 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1068
Query: 1071 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1130
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1069 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1128
Query: 1131 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1190
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1129 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1188
Query: 1191 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1250
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1189 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1248
Query: 1251 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1310
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1249 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1308
Query: 1311 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1370
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1309 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1368
Query: 1371 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1430
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1369 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1428
Query: 1431 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1490
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1429 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1488
Query: 1491 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1550
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1489 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1548
Query: 1551 FESKHN 1556
FESKHN
Sbjct: 1549 FESKHN 1554
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 3085 bits (7998), Expect = 0.0
Identities = 1544/1566 (98%), Positives = 1544/1566 (98%), Gaps = 22/1566 (1%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
Query: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 561
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVD 470
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVD
Sbjct: 562 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 621
Query: 471 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 530
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 622 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 681
Query: 531 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 590
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 682 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 741
Query: 591 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 650
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 742 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 801
Query: 651 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 710
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 802 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 861
Query: 711 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 770
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 862 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 921
Query: 771 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 830
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 922 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 981
Query: 831 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 890
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 982 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 1041
Query: 891 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 950
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 1042 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 1101
Query: 951 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1010
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 1102 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1161
Query: 1011 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1070
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1162 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1221
Query: 1071 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1130
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1222 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1281
Query: 1131 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1190
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1282 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1341
Query: 1191 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1250
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1342 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1401
Query: 1251 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1310
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1402 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1461
Query: 1311 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1370
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1462 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1521
Query: 1371 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1430
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1522 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1581
Query: 1431 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1490
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1582 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1641
Query: 1491 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1550
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1642 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1701
Query: 1551 FESKHN 1556
FESKHN
Sbjct: 1702 FESKHN 1707
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 3079 bits (7983), Expect = 0.0
Identities = 1544/1581 (97%), Positives = 1544/1581 (97%), Gaps = 37/1581 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYP 395
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK---- 416
Query: 396 GFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL 455
GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL
Sbjct: 417 --------GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL 468
Query: 456 RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA 515
RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA
Sbjct: 469 RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA 528
Query: 516 LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE 575
LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE
Sbjct: 529 LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE 588
Query: 576 LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL 635
LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL
Sbjct: 589 LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL 648
Query: 636 SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE 695
SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE
Sbjct: 649 SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE 708
Query: 696 EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV 755
EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV
Sbjct: 709 EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV 768
Query: 756 ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR 815
ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR
Sbjct: 769 ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR 828
Query: 816 SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR 875
SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR
Sbjct: 829 SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR 888
Query: 876 QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA 935
QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA
Sbjct: 889 QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA 948
Query: 936 WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP 995
WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP
Sbjct: 949 WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP 1008
Query: 996 PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK 1055
PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK
Sbjct: 1009 PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK 1068
Query: 1056 DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA 1115
DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA
Sbjct: 1069 DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA 1128
Query: 1116 LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT 1175
LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT
Sbjct: 1129 LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT 1188
Query: 1176 SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT 1235
SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT
Sbjct: 1189 SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT 1248
Query: 1236 LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA 1295
LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA
Sbjct: 1249 LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA 1308
Query: 1296 TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA 1355
TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA
Sbjct: 1309 TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA 1368
Query: 1356 TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA 1415
TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA
Sbjct: 1369 TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA 1428
Query: 1416 AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN 1475
AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN
Sbjct: 1429 AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN 1488
Query: 1476 ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD 1535
ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD
Sbjct: 1489 ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD 1548
Query: 1536 SLSMRRLSRTSAFQSFESKHN 1556
SLSMRRLSRTSAFQSFESKHN
Sbjct: 1549 SLSMRRLSRTSAFQSFESKHN 1569
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 3071 bits (7962), Expect = 0.0
Identities = 1544/1591 (97%), Positives = 1544/1591 (97%), Gaps = 47/1591 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYP 395
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK---- 416
Query: 396 GFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----- 450
GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR
Sbjct: 417 --------GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALK 468
Query: 451 -----DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW 505
DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW
Sbjct: 469 LLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW 528
Query: 506 QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE 565
QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE
Sbjct: 529 QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE 588
Query: 566 QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI 625
QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI
Sbjct: 589 QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI 648
Query: 626 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN 685
LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN
Sbjct: 649 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN 708
Query: 686 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 745
NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME
Sbjct: 709 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 768
Query: 746 RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM 805
RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM
Sbjct: 769 RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM 828
Query: 806 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 865
ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML
Sbjct: 829 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 888
Query: 866 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI 925
VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI
Sbjct: 889 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI 948
Query: 926 IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM 985
IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM
Sbjct: 949 IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM 1008
Query: 986 TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE 1045
TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE
Sbjct: 1009 TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE 1068
Query: 1046 QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL 1105
QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL
Sbjct: 1069 QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL 1128
Query: 1106 EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID 1165
EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID
Sbjct: 1129 EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID 1188
Query: 1166 PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE 1225
PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE
Sbjct: 1189 PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE 1248
Query: 1226 PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP 1285
PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP
Sbjct: 1249 PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP 1308
Query: 1286 STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI 1345
STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI
Sbjct: 1309 STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI 1368
Query: 1346 ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV 1405
ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV
Sbjct: 1369 ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV 1428
Query: 1406 NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG 1465
NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG
Sbjct: 1429 NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG 1488
Query: 1466 DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS 1525
DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS
Sbjct: 1489 DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS 1548
Query: 1526 KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1556
KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1549 KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1579
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 1359 bits (3517), Expect = 0.0
Identities = 684/1204 (56%), Positives = 888/1204 (73%), Gaps = 94/1204 (7%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVR+S+DTKP+++L L+ KEWQ+ELPKL+ISVHGG+Q FEL P++KQ+ GKGLIKAA+TT
Sbjct: 108 YVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTT 167
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI TGGVNTGV +HVGDALK+HAS+S KICTIGIAPWG++EN+ DL+GRDVV PYQT
Sbjct: 168 GAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQT 227
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVA 181
+ NP+SKL VLN++HSHFIL D+GT GKYGAEV+LRR+LEK I+ Q+I+ RIGQGVPVVA
Sbjct: 228 LLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVA 287
Query: 182 LIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLL 241
LI EGGPNVI VLEYL+++PPVPVVVC+G+GRA+D+LA+ HK +EEGG + ++ ++
Sbjct: 288 LIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDII 347
Query: 242 VTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA 301
TI+KTF + + +A HLF LMECMK+KELITVF +GS+ HQDID+AILTALLKG NASA
Sbjct: 348 STIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASA 407
Query: 302 PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHR 361
DQL L LAW+RVDIA++ +F+YGQQW VGSLEQAMLDALV+DRV FVKLLIENGVSMH+
Sbjct: 408 FDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHK 467
Query: 362 FLTISRLEELYNTRHGPSNT-LYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
FLTI RLEELYNT+ GP+N L+HLVRDVK+ GNLPP Y+I+LIDIGLV
Sbjct: 468 FLTIPRLEELYNTKQGPTNPMLFHLVRDVKQ------------GNLPPGYKITLIDIGLV 515
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTT------------------ 462
IEYLMGG YRC YTRKRFR +Y++L G R R GR T+
Sbjct: 516 IEYLMGGTYRCTYTRKRFRLIYNSLGGNNR-----RSGRNTSSSTPQLRKSHESFGNRAD 570
Query: 463 -----------------------------KKREEEVDIDLDDPEINHFPFPFHELMVWAV 493
KKR ++ +D+DDPE FP+P +EL++WA
Sbjct: 571 KKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWAC 630
Query: 494 LMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLA 553
LMKRQ MA F WQHGEE+MAKALVACK+ ++MA+EA ++D+VDD S+EL S DFGQLA
Sbjct: 631 LMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLA 690
Query: 554 VELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 613
VELL+QS++QDE +AMKLLTYELKNWSN+TCL+LAV+++ R F+AHTC+QMLL+DMWMGR
Sbjct: 691 VELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGR 750
Query: 614 LRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEP--EKPTKEK 671
L MRKNS KVIL IL+PP+IL LE+K K +M ++ Q+Q+ H + E + T+E
Sbjct: 751 LNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEI 810
Query: 672 EEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIG 731
E + +L N G K+E E+Q K + +P+ RK Y FY+APIVKFWF TLAY+G
Sbjct: 811 PMEVFKEVRILDSNEG-----KNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLG 865
Query: 732 YLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWN 791
+LML+ ++VLV+ME+ PS QEWIVI+YIFT IEK+REI MSE GK+ QK+KVW +Y+N
Sbjct: 866 FLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFN 925
Query: 792 VTDLIAILLFSVGMILRL---------QDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 842
++D IAI+ F +G LR D GR+IYC+NII+WY+RLLD VN+
Sbjct: 926 ISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQ 985
Query: 843 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 902
GPYVMMIGKM+ +M Y V+IM +VL+SFGV R+AIL+P+E PSW LAK+I + PYWMI+
Sbjct: 986 AGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIF 1045
Query: 903 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 962
GEV+A +ID D I Q+ C G W+ P + A YL V I++VNLLIA FN
Sbjct: 1046 GEVYAYEID------VCANDSVIPQI--CGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFN 1097
Query: 963 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1022
N + +VK+ISN VWK+QRY IM +HE+PVLPPPLII SH+ +F +C R +K D
Sbjct: 1098 NVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKK-----D 1152
Query: 1023 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1082
+ G KLF+T+++ KK+HDFEEQC+E YF EKDD+F+S ++ERIRVT ERVE M ++++
Sbjct: 1153 KTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIK 1212
Query: 1083 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1142
EV +R + +K SLQ++D ++ L+DL L+ LT + +E++K+ + + + + +
Sbjct: 1213 EVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISK 1272
Query: 1143 YIVR 1146
++ +
Sbjct: 1273 HLAQ 1276
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 1257 bits (3253), Expect = 0.0
Identities = 636/1175 (54%), Positives = 843/1175 (71%), Gaps = 77/1175 (6%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R S+DTK D LLHLM KEW++ELPKL+ISVHGG+QNF + K K++F +GL+KAA TT
Sbjct: 111 YIRTSYDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETT 170
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI T G+NTGV +HVGDALK H+S S KI T+GI PWG++ENQ DLIG+DVV YQT
Sbjct: 171 GAWIITEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQT 230
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVA 181
+ NP+SKLT LNSMHSHFIL+D+GT GKYG E+KLRR LEK++SLQKI+ R QGVPVV
Sbjct: 231 LDNPLSKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCRSRQGVPVVG 290
Query: 182 LIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLL 241
L+VEGGPNVI V E ++D PV VVC+G+GRA+D+LAF HK+ + G++ ++++++
Sbjct: 291 LVVEGGPNVILSVWETVKDKDPV--VVCEGTGRAADLLAFTHKHLADEGMLRPQVKEEII 348
Query: 242 VTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA 301
IQ TF ++ Q++HLF ILMECM ++ IT+F SE QD+DLAILTALLKG N SA
Sbjct: 349 CMIQNTFNFSLKQSKHLFQILMECMVHRDCITIFDADSEEQQDLDLAILTALLKGTNLSA 408
Query: 302 PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHR 361
+QL+LA+AW+RVDIA+ I IY Q W +LEQAM DALV+DRVDFVKLLIE GV++HR
Sbjct: 409 SEQLNLAMAWDRVDIAKKHILIYEQHWKPDALEQAMSDALVMDRVDFVKLLIEYGVNLHR 468
Query: 362 FLTISRLEELYNTRHGPSNTL-YHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
FLTI RLEELYNT+ GP+NTL +HLV+DVK+ L YRI+LIDIGLV
Sbjct: 469 FLTIPRLEELYNTKQGPTNTLLHHLVQDVKQH------------TLLSGYRITLIDIGLV 516
Query: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGP-------------------------------- 448
+EYL+G AYR NYTRK FR LY+NL+
Sbjct: 517 VEYLIGRAYRSNYTRKHFRALYNNLYRKYKHQRHSSGNRNESAESTLHSQFIRTAQPYKF 576
Query: 449 KRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHG 508
K I L + RK K +E+ V DDPE F +P+++L+VWAVLMKRQKMA+FFWQHG
Sbjct: 577 KEKSIVLHKSRK--KSKEQNVS---DDPESTGFLYPYNDLLVWAVLMKRQKMAMFFWQHG 631
Query: 509 EEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLA 568
EEA KA++AC L +AMAHEA E+ MVDD S+EL + S+ FGQLA++LL++++KQ+E++A
Sbjct: 632 EEATVKAVIACILYRAMAHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMA 691
Query: 569 MKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGI 628
M LLTYEL+NWSN+TCL+LAV+ R F++HTC+QMLLTDMWMGRL+MRKNS LK+I+ I
Sbjct: 692 MTLLTYELRNWSNSTCLKLAVSGGLRPFVSHTCTQMLLTDMWMGRLKMRKNSWLKIIISI 751
Query: 629 LLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEK---EEEDMELTAMLGRN 685
+LPP+IL+LEFK+K +M ++ Q+Q+ +++ +KE +E D+E R
Sbjct: 752 ILPPTILTLEFKSKAEMSHVPQSQDFQFMWYYSDQNASSSKESASVKEYDLE------RG 805
Query: 686 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 745
+ E + ++S H+ +P RK+YEFY+APIVKFWFYT+AY+ +LMLF Y VLV+M+
Sbjct: 806 HDEKLDENQHFGLESGHQHLPWTRKVYEFYSAPIVKFWFYTMAYLAFLMLFTYTVLVEMQ 865
Query: 746 RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM 805
PS QEW+V YIFT IE +REI +SEPGK QKVKVW+ EYWN+T+ +AI LFS G
Sbjct: 866 PQPSVQEWLVSIYIFTNAIEVVREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGF 925
Query: 806 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 865
+LR D PF + GR+IYC++II+W+ RLLD F VN++ GPYV MI KM +M Y VIIM
Sbjct: 926 VLRWGDPPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMA 985
Query: 866 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI 925
+VL+SFGVAR+AIL P E PSW LA++I + PYWMIYGEV+A +ID Q
Sbjct: 986 IVLLSFGVARKAILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQ--------- 1036
Query: 926 IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM 985
P C G+++ P + A YL V I++VNLLIA FNN + +++SISN +WK+ RY+ IM
Sbjct: 1037 ---PSCPPGSFLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIM 1093
Query: 986 TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE 1045
T+HE+P LPPPLI+ SH+ ++ + LCC H D +E D GLKL+++ ++LKK+HDFEE
Sbjct: 1094 TYHEKPWLPPPLILLSHVGLLLRRLCCHRAPH--DQEEGDVGLKLYLSKEDLKKLHDFEE 1151
Query: 1046 QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL 1105
QC+E+YF EK + N S +ERIRVTSERV M +L+E+NE+ +K SL ++D ++ L
Sbjct: 1152 QCVEKYFHEKMEDVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSLDSQVGHL 1211
Query: 1106 EDLIGRMATALERLTGLERAESNK--IRSRTSSDC 1138
+DL L+ L+ ++ + ++ + R S C
Sbjct: 1212 QDLSALTVDTLKVLSAVDTLQEDEALLAKRKHSTC 1246
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 1198 bits (3099), Expect = 0.0
Identities = 672/1216 (55%), Positives = 818/1216 (67%), Gaps = 124/1216 (10%)
Query: 330 VGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV 389
V +LEQAMLDALVLDRVDFVKLLIENGV+M FLTI RLEELYNTR GP NTL+ LVRDV
Sbjct: 458 VNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDV 517
Query: 390 KKREYPGFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPK 449
KK NLPPDY ISLIDIGLV+EYLMGGAYRCNYTRK FRTLY+NLFGPK
Sbjct: 518 KK------------SNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPK 565
Query: 450 R-----------DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQ 498
R D+ P + +K KK+EEE+DID+DDP ++ F +PFHELMVWAVLMKRQ
Sbjct: 566 RPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQ 625
Query: 499 KMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLD 558
KMA+F WQ GEE+MAKALVACKL KAMAHE+SE+D+VDDISQ+L++NS+DFGQLA+ELLD
Sbjct: 626 KMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLD 685
Query: 559 QSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRK 618
QSYK DEQ+AMKLLTYELKNWSN+TCL+LAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRK
Sbjct: 686 QSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRK 745
Query: 619 NSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMEL 678
N GLKVI+GILLPP+IL LEF+ DD Y + KE E+ KEKEEE+ +
Sbjct: 746 NPGLKVIMGILLPPTILFLEFRTYDDFSYQTS--------KENEDG----KEKEEENTDA 793
Query: 679 TAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNY 738
A G SRK DEE K R IP+G KI EFYNAPIVKFWFYT++Y+GYL+LFNY
Sbjct: 794 NADAG------SRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNY 847
Query: 739 IVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAI 798
++LV+M+ WPS QEWIVISYI +L +EK+REILMSEPGKL QK+KVWLQEYWN+TDL+AI
Sbjct: 848 VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAI 907
Query: 799 LLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMM 858
F +G ILRLQ+QP+ GRVIYCV+II+WYIR+LDIFGVNKYLGPYVMMIGKMMIDM+
Sbjct: 908 STFMIGAILRLQNQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDML 967
Query: 859 YFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID------- 911
YFV+IMLVVLMSFGVARQAIL P E+PSWKLA+NIFYMPYWMIYGEVFADQID
Sbjct: 968 YFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN 1027
Query: 912 PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 971
PPCG+N E+GK +LPPC GAW+ PA+MACYLLVANILLVNLLIAVFNNTFFEVKSI
Sbjct: 1028 PPCGENLYDEEGK--RLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSI 1085
Query: 972 SNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR-KHESDPDERDYGLKL 1030
SNQVWKFQRYQLIMTFH+RPVLPPP+II SH+ +I L R R K E D +ERD GLKL
Sbjct: 1086 SNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKL 1145
Query: 1031 FITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHS 1090
F++D+ELK++H+FEEQC++E+FREK+D SS+DERIRVTSERVENMSMRLEE+NERE
Sbjct: 1146 FLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETF 1205
Query: 1091 MKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSF 1150
MK SLQTVD+RLAQLE+L RM ALE L G++R++ + RSR SS+C +A Y++RQSS
Sbjct: 1206 MKTSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSEC-EATYLLRQSSI 1264
Query: 1151 NSQEGNT-----FKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESI 1205
NS +G + F +E + E+T TSP R ++ SF KD +
Sbjct: 1265 NSADGYSLYRYHFNGEELL---FEDTSLSTSPGTGVRKKTCSFRIKEEKD-----VKTHL 1316
Query: 1206 FKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDP 1265
E SLH + + + A PD H +D
Sbjct: 1317 VPECQNSLHLSLGTSTSA---------------TPDGS----------------HLAVDD 1345
Query: 1266 LDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDY 1325
L N+ E S P + T + + S S++ D+ +S +
Sbjct: 1346 LKNA-------EESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNT 1398
Query: 1326 THLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFG 1385
E N E + + +E +K +RY + +KS SF++S R
Sbjct: 1399 QLTVETTN---IEGTISYPLEETKITRYFPDE--TINACKTMKSRSFVYSRGRKLVGGVN 1453
Query: 1386 VPVKTAEYTSITD---CIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1442
V EY+SITD + +C + P + E + + +
Sbjct: 1454 QDV---EYSSITDQQLTTEWQCQVQKITRSHSTDIP-----YIVSEAAVQAEHKEQFADM 1505
Query: 1443 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1502
+ EA R ++++ + + E LS K ++ + + + + H R
Sbjct: 1506 QDEHHVAEAIPRIPRLSLTITDRNGMENLLS-----VKPDQTLGFPSLRSKSLHGHPRNV 1560
Query: 1503 FSISDKLDRQRNTASL 1518
SI KLDR + +S+
Sbjct: 1561 KSIQGKLDRSGHASSV 1576
Score = 572 bits (1474), Expect = e-162
Identities = 274/334 (82%), Positives = 309/334 (92%), Gaps = 1/334 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MY+RVS+DTKPD LLHLM K+WQLELPKLLISVHGGLQNFE+QPKLKQVFGKGLIKAAMT
Sbjct: 71 MYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMT 130
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGV+TGVI HVGDALKDH+SKSRG++C IGIAPWGIVEN+EDL+G+DV R YQ
Sbjct: 131 TGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQ 190
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNP+SKL+VLN+ H+HFILADNGT GKYGAEVKLRR LEKHISLQKINTR+GQGVP+V
Sbjct: 191 TMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLV 250
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
L+VEGGPNV+SIVLEYL++ PP+PVV+CDGSGRASDIL+F HKY EEGG+INESLR+QL
Sbjct: 251 GLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEEGGIINESLREQL 310
Query: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
LVTIQKTF Y + Q+ LF I+MECMKKKEL+TVFRMGSEG QDI++AILTALLKG N S
Sbjct: 311 LVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNVS 370
Query: 301 APDQLSLALAWNRVDIARSQIFIYGQQW-PVGSL 333
APDQLSLALAWNRVDIARSQIF++G W P+GSL
Sbjct: 371 APDQLSLALAWNRVDIARSQIFVFGPHWPPLGSL 404
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 525 bits (1351), Expect = e-148
Identities = 371/1158 (32%), Positives = 593/1158 (51%), Gaps = 133/1158 (11%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVRVS DT ++ HLMT+ W L++P LLISV GG +NF ++P+LK +F +GL+K A TT
Sbjct: 142 YVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTT 201
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKS---RGKICTIGIAPWGIVENQEDLIGRDVVRP 118
GAWI TGG +TGV++ VG+A++D + S G++ TIG+A WG V +E LI P
Sbjct: 202 GAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFP 261
Query: 119 --YQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQ-KINTRIGQ 175
Y + LT L+S HSHFIL D+GT G+YG E+ LR +LEK IS Q K +
Sbjct: 262 AEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAI 321
Query: 176 GVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINES 235
+P+V +++EGGP + + T P VV +GSGR +D++A I+
Sbjct: 322 KIPIVCVVLEGGPGTLHTIDN--ATTNGTPCVVVEGSGRVADVIAQVANLPVSDITIS-L 378
Query: 236 LRDQLLVTIQKTF-TYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALL 294
++ +L V Q+ F T+T ++ + + +++++L+TVFR G +G QD+D+AIL ALL
Sbjct: 379 IQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALL 438
Query: 295 KGANASA-------PDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVD 347
K + + QL LA+AWNRVDIARS+IF+ QW L M AL+ ++ +
Sbjct: 439 KASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPE 498
Query: 348 FVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV--KKREYPGFGWIYFKGN 405
FVKL +ENGV + F+T L LY PS + ++ V + E P
Sbjct: 499 FVKLFLENGVQLKEFVTWDTLLYLYENLD-PSCLFHSKLQKVLVEDPERPACA------- 550
Query: 406 LPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRG--RKTTK 463
P R+ + + V+ L+G + Y R R L + ++ R K
Sbjct: 551 -PAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYK 609
Query: 464 KREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCK 523
+ V +D P +L++WA++ R+++A W ++ +A AL K+ K
Sbjct: 610 RSSGHVTFTMD---------PIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILK 660
Query: 524 AMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNAT 583
++ E + D S+E+ + ++ A+ + + Y++DE+ A KLLT + W T
Sbjct: 661 ELSKEEEDTDS----SEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTT 716
Query: 584 CLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGL-KVILGILLPPSILSLEFKNK 642
CLQLA+ AK F++H Q LT +W G+L + ++GL +V L +L P +
Sbjct: 717 CLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSV--DNGLWRVTLCMLAFPLL-------- 766
Query: 643 DDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKH 702
LT ++ S R+K ++V +
Sbjct: 767 -----------------------------------LTGLI------SFREKRLQDVGTP- 784
Query: 703 RLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTL 762
+ F+ AP+V F L+Y +L LF Y+++V + PS E + ++F+L
Sbjct: 785 -----AARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSL 839
Query: 763 GIEKMREILMSEPGK--LLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRV 820
E+MR+ L +P + L++K ++ ++WN D+ AILLF G+ RL GRV
Sbjct: 840 VCEEMRQ-LFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYP-GRV 897
Query: 821 IYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILF 880
I ++ I + +RL+ IF ++K LGP ++++ +MM D+ +F+ ++ V ++SFGVA+QAIL
Sbjct: 898 ILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILI 957
Query: 881 PNEEPSWKLAKNIFYMPYWMIYGEV--FADQID---PPCGQNETR-------EDGKIIQL 928
NE L + Y Y I+G++ + D ++ C N T E Q
Sbjct: 958 HNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQR 1017
Query: 929 PPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFH 988
P W+ ++ YLL NILL+NLLIA+FN TF +V+ ++Q+WKFQR+ LI +H
Sbjct: 1018 PAFPE--WLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYH 1075
Query: 989 ERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCI 1048
RP PPP I+ SH+ + + + + P +R LK + +E + +E
Sbjct: 1076 GRPAAPPPFILLSHLQLFIKRVVLK------TPAKRHKQLKNKLEKNEEAALLSWEIYLK 1129
Query: 1049 EEYFREKDDRFNSSNDERIRVTSERVENMSMRLE-EVNEREHSMKASLQTVDIRLAQLED 1107
E Y + + + +++I S +V+ M L+ + +R SM+ RLA LE+
Sbjct: 1130 ENYLQNRQFQQKQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQ-------RLASLEE 1182
Query: 1108 LIGRMATALERLTGLERA 1125
+ + A AL + RA
Sbjct: 1183 QVAQTARALHWIVRTLRA 1200
>gi|21314671 transient receptor potential cation channel, subfamily M,
member 4 [Homo sapiens]
Length = 1214
Score = 473 bits (1217), Expect = e-133
Identities = 349/1162 (30%), Positives = 587/1162 (50%), Gaps = 101/1162 (8%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
++R+S T P + L+T+ W P L++SV GG LQ L+ + +GL++AA +T
Sbjct: 90 FLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQST 149
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRG--KICTIGIAPWGIVENQEDLIGRDVVRP- 118
GAWI TGG++TG+ RHVG A++DH S G K+ +G+APWG+V N++ LI P
Sbjct: 150 GAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPA 209
Query: 119 -YQTMSNPMSKLTV-LNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-IGQ 175
Y+ +P + L+ +S F L D+GT G G E + R +LE +IS QK G
Sbjct: 210 RYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGI 269
Query: 176 GVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYS---EEGGLI 232
+PV+ L+++G +++ + + +P ++ GSG A+D LA + + GG
Sbjct: 270 DIPVLLLLIDGDEKMLTRIENATQ--AQLPCLLVAGSGGAADCLAETLEDTLAPGSGGAR 327
Query: 233 NESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTA 292
RD++ + F + + + L + M +KEL+TV+ +G ++ + +L A
Sbjct: 328 QGEARDRI-----RRF-FPKGDLEVLQAQVERIMTRKELLTVYS-SEDGSEEFETIVLKA 380
Query: 293 LLKGANASAP----DQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF 348
L+K +S D+L LA+AWNRVDIA+S++F QW LE +++DAL+ DR +F
Sbjct: 381 LVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEF 440
Query: 349 VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNL-- 406
V+LLI +G+S+ FLT RL +LY+ PSN+L + D G KG
Sbjct: 441 VRLLISHGLSLGHFLTPMRLAQLYSA--APSNSLIRNLLDQASHS-AGTKAPALKGGAAE 497
Query: 407 --PPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKK 464
PPD +G V+ L+G Y G D P + ++
Sbjct: 498 LRPPD-------VGHVLRMLLGKMCAPRYPS-----------GGAWDPHPGQGFGESMYL 539
Query: 465 REEEVDIDLD-DPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCK 523
++ L D + P+ +L++WA+L+ R +MA++FW+ G A++ AL AC L +
Sbjct: 540 LSDKATSPLSLDAGLGQAPWS--DLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLR 597
Query: 524 AMAH---EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWS 580
MA +A E D++ + F + V+L + Y+ E A +LL W
Sbjct: 598 VMARLEPDAEEAARRKDLAFK-------FEGMGVDLFGECYRSSEVRAARLLLRRCPLWG 650
Query: 581 NATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILS--LE 638
+ATCLQLA+ A R F A Q LLT W G + ++L PP I + +
Sbjct: 651 DATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWA-LVLAFFCPPLIYTRLIT 709
Query: 639 FKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEV 698
F+ ++ P + + E P E+ + + GR R +
Sbjct: 710 FRKSEEEPTREELEFDMDSVINGEGPVGTADPAEKTPLGVPRQSGRPGCCGGRCGGRRCL 769
Query: 699 QSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWP-STQEWIVIS 757
R+ + F+ AP+ F ++Y+ +L+LF+ ++LV + P + E ++
Sbjct: 770 ----------RRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYF 819
Query: 758 YIFTLGIEKMREILMSEPGKLL------------QKVKVWLQEYWNVTDLIAILLFSVGM 805
+ FTL E++R+ L G L Q+++++L + WN DL+A+ F +G+
Sbjct: 820 WAFTLLCEELRQGLSGGGGSLASGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGV 879
Query: 806 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 865
RL + GR + C++ + + +RLL IF VNK LGP ++++ KMM D+ +F+ +
Sbjct: 880 GCRLTPGLYHL-GRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLG 938
Query: 866 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQ--NETREDG 923
V L+++GVA + +L P + + + +FY PY I+G++ + +D + N + E G
Sbjct: 939 VWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPG 998
Query: 924 KIIQLPPCKTGA-------WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
P + G W+V ++ +LLVANILLVNLLIA+F+ TF +V+ S+ W
Sbjct: 999 FWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYW 1058
Query: 977 KFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDE 1036
K QRY+LI FH RP L PP I+ SH+ ++ + LC R R + ++ +++++ +
Sbjct: 1059 KAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRSPQPSSPALEH-FRVYLSKEA 1117
Query: 1037 LKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQ 1096
+K+ +E E + + S+ ER++ TS++V+ +L + E E +K
Sbjct: 1118 ERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLK---- 1173
Query: 1097 TVDIRLAQLEDLIGRMATALER 1118
++ + Q ++G +A AL R
Sbjct: 1174 VLEREVQQCSRVLGWVAEALSR 1195
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 466 bits (1199), Expect = e-131
Identities = 343/1135 (30%), Positives = 563/1135 (49%), Gaps = 115/1135 (10%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
+VRV P +L L+ EW L P L++S+ G Q F ++ L+ V KGL+KAA +T
Sbjct: 40 FVRVPSGVAPSVLFDLLLAEWHLPAPNLVVSLVGEEQPFAMKSWLRDVLRKGLVKAAQST 99
Query: 62 GAWIFTGGVNTGVIRHVGDALKDH---ASKSRGKICTIGIAPWGIV-------ENQEDLI 111
GAWI T + G+ RHVG A++DH ++ ++ ++ +G+A G V E QED
Sbjct: 100 GAWILTSALRVGLARHVGQAVRDHSLASTSTKVRVVAVGMASLGRVLHRRILEEAQEDF- 158
Query: 112 GRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINT 171
V + L L+S SHFIL + G GK +LR +LEKHIS Q
Sbjct: 159 ---PVHYPEDDGGSQGPLCSLDSNLSHFILVEPGPPGKGDGLTELRLRLEKHISEQ---- 211
Query: 172 RIGQG------VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKY 225
R G G +PV+ L+V G PN + + + P ++V GSG +D+LA
Sbjct: 212 RAGYGGTGSIEIPVLCLLVNGDPNTLERISRAVEQAAPWLILV--GSGGIADVLA----- 264
Query: 226 SEEGGLINESLRDQLLV--TIQKTFT-------YTRTQAQHLFIILMECMKKKELITVFR 276
L+N+ LLV +K F ++ +L + L+TV+
Sbjct: 265 ----ALVNQ---PHLLVPKVAEKQFKEKFPSKHFSWEDIVRWTKLLQNITSHQHLLTVYD 317
Query: 277 MGSEGHQDIDLAILTALLKGANASAP------DQLSLALAWNRVDIARSQIFIYGQQWPV 330
EG +++D IL AL+K + + D+L LA+AW+RVDIA+S+IF +W
Sbjct: 318 FEQEGSEELDTVILKALVKACKSHSQEPQDYLDELKLAVAWDRVDIAKSEIFNGDVEWKS 377
Query: 331 GSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVK 390
LE+ M+DALV ++ +FV+L ++NG + FLT RL+ELY + S L R +
Sbjct: 378 CDLEEVMVDALVSNKPEFVRLFVDNGADVADFLTYGRLQELYRSVSRKSLLFDLLQRKQE 437
Query: 391 KREYPGFGWIYFKGNLPP--DYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP 448
+ G + PP SL ++ V++ + A R Y
Sbjct: 438 EARLTLAGLGTQQAREPPAGPPAFSLHEVSRVLKDFLQDACRGFY--------------- 482
Query: 449 KRDDIP--LRRGRKTTKKRE--EEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFF 504
+D P RR K KR ++ +DL+ N P+ +L +WAVL R +MA +F
Sbjct: 483 -QDGRPGDRRRAEKGPAKRPTGQKWLLDLNQKSEN----PWRDLFLWAVLQNRHEMATYF 537
Query: 505 WQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQD 564
W G+E +A AL ACK+ K M+H +E + + + +LA++L + Y
Sbjct: 538 WAMGQEGVAAALAACKILKEMSHLETEAEAARATRE------AKYERLALDLFSECYSNS 591
Query: 565 EQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKV 624
E A LL + WS TCL LA A + F AH Q LT +W G M + +
Sbjct: 592 EARAFALLVRRNRCWSKTTCLHLATEADAKAFFAHDGVQAFLTRIWWG--DMAAGTPILR 649
Query: 625 ILGILLPPSILSLEFKN-KDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLG 683
+LG L P+++ ++ P + ++ LQ+ ++ + EK + +E
Sbjct: 650 LLGAFLCPALVYTNLITFSEEAPLRTGLED--LQDLDSLDTEKSPLYGLQSRVEELVEAP 707
Query: 684 RNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVK 743
R G+ R + L + +F+ AP+ F + Y +L LF Y++LV
Sbjct: 708 RAQGDRG-----------PRAVFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFTYVLLVD 756
Query: 744 ME---RWPSTQEWIVISYIFTLGIEKMRE-ILMSEPGKLLQKVKVWLQEYWNVTDLIAIL 799
+ PS E + ++FTL +E++R+ E L++K +++ + WN D++AI
Sbjct: 757 FRPPPQGPSGPEVTLYFWVFTLVLEEIRQGFFTDEDTHLVKKFTLYVGDNWNKCDMVAIF 816
Query: 800 LFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMY 859
LF VG+ R+ F + GR + ++ + + +RL+ IF ++K LGP ++++ +MM D+ +
Sbjct: 817 LFIVGVTCRMLPSAFEA-GRTVLAMDFMVFTLRLIHIFAIHKQLGPKIIVVERMMKDVFF 875
Query: 860 FVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNET 919
F+ + V L+++GV QA+L P++ + + + Y PY I+G++ D+ID N +
Sbjct: 876 FLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEID-EARVNCS 934
Query: 920 REDGKIIQLPPCKT--GAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWK 977
+ P C + W+V ++ +LLV N+LL+NLLIA+F+ TF V+ ++ WK
Sbjct: 935 THPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWK 994
Query: 978 FQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDEL 1037
FQRY LI+ +HERP L PP I+ SH+++ + + + +H+ + ERD + D
Sbjct: 995 FQRYNLIVEYHERPALAPPFILLSHLSLTLRRVFKKEAEHKREHLERD------LPDPLD 1048
Query: 1038 KKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK 1092
+KV +E E + + + R S E +R T+ RV+ ++ L + E+E +K
Sbjct: 1049 QKVVTWETVQKENFLSKMEKRRRDSEGEVLRKTAHRVDFIAKYLGGLREQEKRIK 1103
>gi|45935368 transient receptor potential cation channel, subfamily
M, member 3 isoform h [Homo sapiens]
Length = 230
Score = 464 bits (1194), Expect = e-130
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 230
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 230
>gi|55953096 transient receptor potential cation channel, subfamily
M, member 3 isoform c [Homo sapiens]
Length = 255
Score = 450 bits (1158), Expect = e-126
Identities = 230/255 (90%), Positives = 230/255 (90%), Gaps = 25/255 (9%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 216 SDILAFGHKYSEEGG 230
SDILAFGHKYSEEGG
Sbjct: 241 SDILAFGHKYSEEGG 255
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 283 bits (724), Expect = 9e-76
Identities = 194/650 (29%), Positives = 322/650 (49%), Gaps = 78/650 (12%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R+S DT ++L L+T+ W L+ P L+ISV GG +NF L+P+++++F + LI A +
Sbjct: 117 YIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSR-LIYIAQSK 175
Query: 62 GAWIFTGGVNTGVIRHVGDALKDH--ASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPY 119
GAWI TGG + G+++++G+ ++D+ + S I IGIA WG+V N++ LI Y
Sbjct: 176 GAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGY 235
Query: 120 QTMSNPMSKLT-----VLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKI-NTRI 173
M T +L++ H+H +L DNG G E KLR QLEK+IS + I ++
Sbjct: 236 FLAQYLMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQDSNY 295
Query: 174 GQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLIN 233
G +P+V GG + + +++ +P VV +GSG+ +D++A E L +
Sbjct: 296 GGKIPIVCFAQGGGKETLKAINTSIKNK--IPCVVVEGSGQIADVIA--SLVEVEDALTS 351
Query: 234 ESLRDQLLVTIQKTFTYTRTQAQHLFII-LMECMKKKELITVFRMGSEGHQDIDLAILTA 292
+++++L+ + +T + + +I L E ++ L+TV +M G + + AI A
Sbjct: 352 SAVKEKLVRFLPRTVSRLPEEETESWIKWLKEILECSHLLTVIKMEEAGDEIVSNAISYA 411
Query: 293 LLKGANASAPD------QLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRV 346
L K + S D QL L L WN++D+A +IF ++W L++ M AL+ DR
Sbjct: 412 LYKAFSTSEQDKDNWNGQLKLLLEWNQLDLANDEIFTNDRRWESADLQEVMFTALIKDRP 471
Query: 347 DFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNL 406
FV+L +ENG+++ +FLT L EL++ +TL + + K Y + F L
Sbjct: 472 KFVRLFLENGLNLRKFLTHDVLTELFSNHF---STLVYRNLQIAKNSY-NDALLTFVWKL 527
Query: 407 PPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKRE 466
++R R RK +
Sbjct: 528 VANFR--------------------------------------------RGFRKEDRNGR 543
Query: 467 EEVDIDLDD--PEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKA 524
+E+DI+L D P H P L +WA+L +++++ W+ AL A KL K
Sbjct: 544 DEMDIELHDVSPITRH---PLQALFIWAILQNKKELSKVIWEQTRGCTLAALGASKLLKT 600
Query: 525 MAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATC 584
+A ++ + + S+EL + ++ AVEL + Y DE LA +LL Y + W + C
Sbjct: 601 LAKVKNDINAAGE-SEEL---ANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNC 656
Query: 585 LQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSI 634
L+LAV A + FIA Q L+ W G + R K+IL + + P +
Sbjct: 657 LELAVEATDQHFIAQPGVQNFLSKQWYGEI-SRDTKNWKIILCLFIIPLV 705
Score = 172 bits (435), Expect = 3e-42
Identities = 109/370 (29%), Positives = 193/370 (52%), Gaps = 32/370 (8%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMS 773
F+ +P V F + + YI +L+LF Y++L+ P E ++ S +F L +++R+ ++
Sbjct: 730 FFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVN 789
Query: 774 EPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRS--DGRVIYCVNIIYWYI 831
+ + WNV D + + F G++ RL S GRVI+C++ I + +
Sbjct: 790 GVN--------YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTL 841
Query: 832 RLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAK 891
RL+ IF V++ LGP ++M+ +M+ID+ +F+ + V +++FGVARQ IL NE+ + +
Sbjct: 842 RLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFR 901
Query: 892 NIFYMPYWMIYGEVFADQID------PPCGQNETREDGKIIQLPP---CKTGAWIVPAIM 942
++ Y PY ++G+V +D +D C ++L + WI ++
Sbjct: 902 SVIYEPYLAMFGQVPSD-VDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLV 960
Query: 943 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 1002
Y+L NILLVNLL+A+F T V+ ++QVWKFQRY L+ + R +P P I+F++
Sbjct: 961 CIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAY 1020
Query: 1003 MTMIFQ---HLCCRWRKHES------DPDERDYGLKLFITDDELKKVHDFEEQCIEEY-- 1051
M+ + CC+ + ES + D + + ++ L K++ EE
Sbjct: 1021 FYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRH 1080
Query: 1052 -FREKDDRFN 1060
FR+ D + N
Sbjct: 1081 RFRQLDTKLN 1090
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
Query: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1028
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
Query: 1029 KLFITDDELKKVHDFEE 1045
D L++ H ++E
Sbjct: 519 IGRRAADNLRRHHQYQE 535
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1028
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1029 KLFITDDELKKVHDFEE 1045
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 536 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 588
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 589 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 631
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1028
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1029 KLFITDDELKKVHDFEE 1045
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 536 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 588
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 589 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 631
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|7706747 transient receptor potential cation channel, subfamily C,
member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1028
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1029 KLFITDDELKKVHDFEE 1045
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 536 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 588
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 589 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 631
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 78.2 bits (191), Expect = 6e-14
Identities = 71/343 (20%), Positives = 150/343 (43%), Gaps = 67/343 (19%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLC 1011
KF R +L M++ E V+P P ++ + I+ HLC
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLC 678
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 536 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 588
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 589 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 631
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|6912736 transient receptor potential cation channel, subfamily C,
member 5 [Homo sapiens]
Length = 973
Score = 71.2 bits (173), Expect = 7e-12
Identities = 76/360 (21%), Positives = 154/360 (42%), Gaps = 77/360 (21%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L + +IV + P+ EW+++ ++ +
Sbjct: 359 FIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGE 418
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGR------- 819
++E M + G ++ ++WN+ D L+ + L++ + R
Sbjct: 419 IKE--MWDGG-----FTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEM 471
Query: 820 --------VIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ ++ I +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 472 WHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 531
Query: 872 GVARQAILF---------PNEEPSWKLAK--NIF-------YMPYWMIYG--EVFADQID 911
+ F PN + K N F +W ++G ++ +
Sbjct: 532 ANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 912 PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 971
++E E ++ + Y +++ ++L+N+LIA+ NN++ +
Sbjct: 592 ---ARHEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 634
Query: 972 SNQVWKFQRYQLIMT-FHERPVLPPPLII------FSHMTMIFQHLCCRWRKHESDPDER 1024
++ WKF R +L M+ F E LPPP I F ++ F + C R DPD R
Sbjct: 635 ADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKR----DPDGR 690
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 3e-09
Identities = 60/310 (19%), Positives = 135/310 (43%), Gaps = 60/310 (19%)
Query: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTF-FEVKSISNQV 975
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ +
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRAADNL 635
Query: 976 WKFQRYQLIM 985
+ +YQ +M
Sbjct: 636 RRHHQYQEVM 645
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 536 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 588
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 589 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 631
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 57.0 bits (136), Expect = 1e-07
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 810 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 865
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
Query: 866 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 919
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
Query: 920 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 979
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
Query: 980 RYQLIMT-FHERPVLPPP 996
R +L ++ F E LP P
Sbjct: 691 RAKLWLSYFDEGRTLPAP 708
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 781 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 835
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 569 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 628
Query: 836 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 891
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 629 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 688
Query: 892 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 951
F +W I+G + + D K I+ I + Y + +
Sbjct: 689 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 733
Query: 952 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 996
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 734 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 779
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 705 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 763
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 641 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 700
Query: 764 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 806
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 701 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 743
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 781 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 835
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 496 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 555
Query: 836 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 891
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 556 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 615
Query: 892 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 951
F +W I+G + + D K I+ I + Y + +
Sbjct: 616 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 660
Query: 952 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 996
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 661 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 706
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 705 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 763
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 568 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 627
Query: 764 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 806
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 628 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 670
>gi|5730102 transient receptor potential cation channel, subfamily C,
member 6 [Homo sapiens]
Length = 931
Score = 54.3 bits (129), Expect = 9e-07
Identities = 70/349 (20%), Positives = 133/349 (38%), Gaps = 89/349 (25%)
Query: 749 STQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR 808
S E ++IS++ + + +EI P K +L E WN+ D + +F+ I R
Sbjct: 492 SWMEMLIISWVIGMIWAECKEIWTQGP-------KEYLFELWNMLDFGMLAIFAASFIAR 544
Query: 809 LQ-------------------------------------------DQPFRSDGRVIYCVN 825
D S+G +Y +
Sbjct: 545 FMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEG--LYAIA 602
Query: 826 IIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGV-----------A 874
++ + R+ I N+ GP + +G+ + D+ F++I ++V ++F + A
Sbjct: 603 VVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA 662
Query: 875 RQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTG 934
+Q F E S+K +W I+G + G ++
Sbjct: 663 KQNEAFTTVEESFKTL-------FWAIFGLSEVKSVVINYNHKFIENIGYVLY------- 708
Query: 935 AWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVL 993
Y + I+L+N+LIA+ N++F E++ ++ WKF R +L + F E L
Sbjct: 709 --------GVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTL 760
Query: 994 PPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHD 1042
P P + +F +L + +K S+ + K F D E+ K+++
Sbjct: 761 PVPFNLVPSPKSLF-YLLLKLKKWISELFQGH--KKGFQEDAEMNKINE 806
Score = 36.6 bits (83), Expect = 0.19
Identities = 21/103 (20%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 705 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM-ERWPSTQEWIVISYIFTLG 763
I LGR + + + ++ + IG L++Y + K E + + +E + G
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFG 684
Query: 764 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 806
+ +++ ++++ K ++ + L +NVT +I +L + MI
Sbjct: 685 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMI 727
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 52.8 bits (125), Expect = 3e-06
Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 843 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 901
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P +L Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPE-ELGHFYDYPMALFS 532
Query: 902 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 961
E+F ID P N + LP ++ A + ++A +L++NLLIA+
Sbjct: 533 TFELFLTIIDGPANYN--------VDLP------FMYSITYAAFAIIATLLMLNLLIAMM 578
Query: 962 NNTFFEVKSISNQVWKFQ 979
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAHERDELWRAQ 596
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 843 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 901
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P+ L + Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPT-SLGQFYDYPMALFT 532
Query: 902 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 961
E+F ID P + + LP ++ + + ++A +L++NL IA+
Sbjct: 533 TFELFLTVIDAPANYD--------VDLP------FMFSIVNFAFAIIATLLMLNLFIAMM 578
Query: 962 NNTFFEVKSISNQVWKFQ 979
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAQERDELWRAQ 596
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 716 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 773
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
Query: 774 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 817
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
Query: 818 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 877
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
Query: 878 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 918
+ + ++E K IF + +W I+ E
Sbjct: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
Query: 919 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 978
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
Query: 979 QRYQLIMT-FHERPVLPPPLII 999
R +L ++ F ++ LPPP I
Sbjct: 629 ARAKLWLSYFDDKCTLPPPFNI 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,409,470
Number of Sequences: 37866
Number of extensions: 2756396
Number of successful extensions: 13568
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 12808
Number of HSP's gapped (non-prelim): 684
length of query: 1556
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1440
effective length of database: 13,855,062
effective search space: 19951289280
effective search space used: 19951289280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.