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Search of human proteins with 154091314
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154091314 transient receptor potential cation channel,
subfamily M, member 3 isoform k [Homo sapiens]
(1707 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154091314 transient receptor potential cation channel, subfam... 3443 0.0
gi|154091320 transient receptor potential cation channel, subfam... 3121 0.0
gi|154091312 transient receptor potential cation channel, subfam... 3112 0.0
gi|154091308 transient receptor potential cation channel, subfam... 3107 0.0
gi|154091318 transient receptor potential cation channel, subfam... 3094 0.0
gi|154091316 transient receptor potential cation channel, subfam... 3085 0.0
gi|154091310 transient receptor potential cation channel, subfam... 3080 0.0
gi|148612863 transient receptor potential cation channel, subfam... 1462 0.0
gi|18921093 transient receptor potential cation channel, subfami... 1358 0.0
gi|94538366 transient receptor potential cation channel, subfami... 1234 0.0
gi|4507689 transient receptor potential cation channel, subfamil... 564 e-160
gi|21314671 transient receptor potential cation channel, subfami... 507 e-143
gi|11225266 transient receptor potential cation channel, subfami... 470 e-132
gi|45935368 transient receptor potential cation channel, subfami... 464 e-130
gi|55953096 transient receptor potential cation channel, subfami... 450 e-126
gi|109689695 transient receptor potential cation channel, subfam... 322 3e-87
gi|209863032 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863030 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863026 transient receptor potential cation channel, subfam... 80 1e-14
gi|7706747 transient receptor potential cation channel, subfamil... 80 1e-14
gi|209863024 transient receptor potential cation channel, subfam... 78 6e-14
gi|6912736 transient receptor potential cation channel, subfamil... 71 8e-12
gi|209863028 transient receptor potential cation channel, subfam... 62 4e-09
gi|9966865 transient receptor potential cation channel, subfamil... 57 2e-07
gi|194733735 transient receptor potential cation channel, subfam... 57 2e-07
gi|4507687 transient receptor potential cation channel, subfamil... 57 2e-07
gi|5730102 transient receptor potential cation channel, subfamil... 54 1e-06
gi|21314682 transient receptor potential cation channel, subfami... 53 3e-06
gi|17505200 transient receptor potential cation channel, subfami... 50 1e-05
gi|4507685 transient receptor potential cation channel, subfamil... 47 2e-04
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 3443 bits (8928), Expect = 0.0
Identities = 1707/1707 (100%), Positives = 1707/1707 (100%)
Query: 1 MPEPWGTVYFLGIAQVFSFLFSWWNLEGVMNQADAPRPLNWTIRKLCHAAFLPSVRLLKA 60
MPEPWGTVYFLGIAQVFSFLFSWWNLEGVMNQADAPRPLNWTIRKLCHAAFLPSVRLLKA
Sbjct: 1 MPEPWGTVYFLGIAQVFSFLFSWWNLEGVMNQADAPRPLNWTIRKLCHAAFLPSVRLLKA 60
Query: 61 QKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDI 120
QKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDI
Sbjct: 61 QKSWIERAFYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDI 120
Query: 121 QSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELP 180
QSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELP
Sbjct: 121 QSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELP 180
Query: 181 KLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS 240
KLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS
Sbjct: 181 KLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHAS 240
Query: 241 KSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTT 300
KSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTT
Sbjct: 241 KSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTT 300
Query: 301 GKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVV 360
GKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVV
Sbjct: 301 GKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVV 360
Query: 361 VCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMK 420
VCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMK
Sbjct: 361 VCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMK 420
Query: 421 KKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQ 480
KKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQ
Sbjct: 421 KKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQ 480
Query: 481 WPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVR 540
WPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVR
Sbjct: 481 WPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVR 540
Query: 541 DVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGM 600
DVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGM
Sbjct: 541 DVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGM 600
Query: 601 EDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGE 660
EDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGE
Sbjct: 601 EDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGE 660
Query: 661 EAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAM 720
EAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAM
Sbjct: 661 EAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAM 720
Query: 721 KLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL 780
KLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL
Sbjct: 721 KLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGIL 780
Query: 781 LPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGES 840
LPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGES
Sbjct: 781 LPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGES 840
Query: 841 SRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPS 900
SRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPS
Sbjct: 841 SRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPS 900
Query: 901 TQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRL 960
TQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRL
Sbjct: 901 TQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRL 960
Query: 961 QDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLM 1020
QDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLM
Sbjct: 961 QDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLM 1020
Query: 1021 SFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLP 1080
SFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLP
Sbjct: 1021 SFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLP 1080
Query: 1081 PCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHE 1140
PCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHE
Sbjct: 1081 PCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHE 1140
Query: 1141 RPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIE 1200
RPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIE
Sbjct: 1141 RPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIE 1200
Query: 1201 EYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLI 1260
EYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLI
Sbjct: 1201 EYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLI 1260
Query: 1261 GRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGE 1320
GRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGE
Sbjct: 1261 GRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGE 1320
Query: 1321 ETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAP 1380
ETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAP
Sbjct: 1321 ETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAP 1380
Query: 1381 AAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAP 1440
AAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAP
Sbjct: 1381 AAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAP 1440
Query: 1441 SSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSK 1500
SSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSK
Sbjct: 1441 SSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSK 1500
Query: 1501 SSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQ 1560
SSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQ
Sbjct: 1501 SSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQ 1560
Query: 1561 AIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSE 1620
AIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSE
Sbjct: 1561 AIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSE 1620
Query: 1621 RTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSK 1680
RTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSK
Sbjct: 1621 RTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSK 1680
Query: 1681 PEGRGDSLSMRRLSRTSAFQSFESKHN 1707
PEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1681 PEGRGDSLSMRRLSRTSAFQSFESKHN 1707
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 3121 bits (8091), Expect = 0.0
Identities = 1554/1554 (100%), Positives = 1554/1554 (100%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 573
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
Query: 574 YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 633
YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP
Sbjct: 421 YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 480
Query: 634 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 693
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL
Sbjct: 481 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 540
Query: 694 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 753
NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS
Sbjct: 541 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 600
Query: 754 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 813
QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE
Sbjct: 601 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 660
Query: 814 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 873
EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF
Sbjct: 661 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 720
Query: 874 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 933
WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV
Sbjct: 721 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 780
Query: 934 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 993
KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY
Sbjct: 781 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 840
Query: 994 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 1053
LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY
Sbjct: 841 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 900
Query: 1054 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 1113
GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN
Sbjct: 901 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 960
Query: 1114 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1173
NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD
Sbjct: 961 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1020
Query: 1174 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1233
ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE
Sbjct: 1021 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1080
Query: 1234 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1293
EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA
Sbjct: 1081 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1140
Query: 1294 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1353
YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL
Sbjct: 1141 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1200
Query: 1354 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1413
ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD
Sbjct: 1201 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1260
Query: 1414 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1473
IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS
Sbjct: 1261 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1320
Query: 1474 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1533
SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA
Sbjct: 1321 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1380
Query: 1534 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1593
NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP
Sbjct: 1381 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1440
Query: 1594 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1653
SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS
Sbjct: 1441 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1500
Query: 1654 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1707
FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1501 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1554
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 3112 bits (8068), Expect = 0.0
Identities = 1554/1566 (99%), Positives = 1554/1566 (99%), Gaps = 12/1566 (0%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 561
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 562 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 621
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 480
Query: 622 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 681
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 481 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 540
Query: 682 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 741
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 541 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 600
Query: 742 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 801
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 601 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 660
Query: 802 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 861
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 661 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 720
Query: 862 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 921
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 721 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 780
Query: 922 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 981
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 781 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 840
Query: 982 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 1041
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 841 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 900
Query: 1042 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 1101
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 901 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 960
Query: 1102 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1161
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 961 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1020
Query: 1162 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1221
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1021 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1080
Query: 1222 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1281
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1081 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1140
Query: 1282 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1341
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1141 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1200
Query: 1342 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1401
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1201 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1260
Query: 1402 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1461
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1261 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1320
Query: 1462 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1521
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1321 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1380
Query: 1522 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1581
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1381 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1440
Query: 1582 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1641
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1441 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1500
Query: 1642 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1701
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1501 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1560
Query: 1702 FESKHN 1707
FESKHN
Sbjct: 1561 FESKHN 1566
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 3107 bits (8055), Expect = 0.0
Identities = 1554/1579 (98%), Positives = 1554/1579 (98%), Gaps = 25/1579 (1%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 325
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 326 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 368
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 369 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 428
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 429 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 488
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 489 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 548
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 549 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 608
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 480
Query: 609 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 668
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 481 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 540
Query: 669 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 728
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 541 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 600
Query: 729 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 788
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 601 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 660
Query: 789 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 848
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 661 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 720
Query: 849 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 908
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 721 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 780
Query: 909 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 968
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 781 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 840
Query: 969 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 1028
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 841 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 900
Query: 1029 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 1088
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 901 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 960
Query: 1089 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1148
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 961 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1020
Query: 1149 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1208
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 1021 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1080
Query: 1209 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1268
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1081 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1140
Query: 1269 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1328
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1141 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1200
Query: 1329 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1388
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1201 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1260
Query: 1389 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1448
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1261 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1320
Query: 1449 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1508
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1321 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1380
Query: 1509 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1568
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1381 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1440
Query: 1569 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1628
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1441 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1500
Query: 1629 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1688
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1501 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1560
Query: 1689 SMRRLSRTSAFQSFESKHN 1707
SMRRLSRTSAFQSFESKHN
Sbjct: 1561 SMRRLSRTSAFQSFESKHN 1579
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 3094 bits (8021), Expect = 0.0
Identities = 1544/1554 (99%), Positives = 1544/1554 (99%), Gaps = 10/1554 (0%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 573
RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCN 420
Query: 574 YTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 633
YTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP
Sbjct: 421 YTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVDIDLDDPEINHFP 470
Query: 634 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 693
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL
Sbjct: 471 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 530
Query: 694 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 753
NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS
Sbjct: 531 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 590
Query: 754 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 813
QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE
Sbjct: 591 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAE 650
Query: 814 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 873
EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF
Sbjct: 651 EPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKF 710
Query: 874 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 933
WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV
Sbjct: 711 WFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKV 770
Query: 934 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 993
KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY
Sbjct: 771 KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKY 830
Query: 994 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 1053
LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY
Sbjct: 831 LGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY 890
Query: 1054 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 1113
GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN
Sbjct: 891 GEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFN 950
Query: 1114 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1173
NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD
Sbjct: 951 NTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPD 1010
Query: 1174 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1233
ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE
Sbjct: 1011 ERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE 1070
Query: 1234 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1293
EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA
Sbjct: 1071 EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAA 1130
Query: 1294 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1353
YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL
Sbjct: 1131 YIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL 1190
Query: 1354 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1413
ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD
Sbjct: 1191 ESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCD 1250
Query: 1414 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1473
IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS
Sbjct: 1251 IDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFS 1310
Query: 1474 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1533
SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA
Sbjct: 1311 SDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA 1370
Query: 1534 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1593
NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP
Sbjct: 1371 NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHP 1430
Query: 1594 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1653
SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS
Sbjct: 1431 SSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKS 1490
Query: 1654 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1707
FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1491 FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1544
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 3085 bits (7998), Expect = 0.0
Identities = 1544/1566 (98%), Positives = 1544/1566 (98%), Gaps = 22/1566 (1%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 393
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQL 240
Query: 394 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 453
LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS
Sbjct: 241 LVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANAS 300
Query: 454 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 513
APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH
Sbjct: 301 APDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMH 360
Query: 514 RFLTISRLEELYNTRHGPSNTLYHLVRDVKK------------GNLPPDYRISLIDIGLV 561
RFLTISRLEELYNTRHGPSNTLYHLVRDVKK GNLPPDYRISLIDIGLV
Sbjct: 361 RFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYPGFGWIYFKGNLPPDYRISLIDIGLV 420
Query: 562 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVD 621
IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRRGRKTTKKREEEVD
Sbjct: 421 IEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRRGRKTTKKREEEVD 470
Query: 622 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 681
IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS
Sbjct: 471 IDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEAS 530
Query: 682 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 741
ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA
Sbjct: 531 ENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVA 590
Query: 742 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 801
AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
Sbjct: 591 AKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ 650
Query: 802 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 861
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK
Sbjct: 651 AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRK 710
Query: 862 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 921
IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI
Sbjct: 711 IYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREI 770
Query: 922 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 981
LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY
Sbjct: 771 LMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWY 830
Query: 982 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 1041
IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA
Sbjct: 831 IRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLA 890
Query: 1042 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 1101
KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
Sbjct: 891 KNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN 950
Query: 1102 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1161
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL
Sbjct: 951 ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHL 1010
Query: 1162 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1221
CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT
Sbjct: 1011 CCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVT 1070
Query: 1222 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1281
SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI
Sbjct: 1071 SERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNKI 1130
Query: 1282 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1341
RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS
Sbjct: 1131 RSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHSFYS 1190
Query: 1342 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1401
VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
Sbjct: 1191 VNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID 1250
Query: 1402 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1461
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF
Sbjct: 1251 IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDF 1310
Query: 1462 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1521
EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH
Sbjct: 1311 EDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKSH 1370
Query: 1522 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1581
SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC
Sbjct: 1371 SFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVEDLTC 1430
Query: 1582 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1641
CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE
Sbjct: 1431 CHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSYSAE 1490
Query: 1642 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1701
EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
Sbjct: 1491 EPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS 1550
Query: 1702 FESKHN 1707
FESKHN
Sbjct: 1551 FESKHN 1556
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 3080 bits (7985), Expect = 0.0
Identities = 1544/1579 (97%), Positives = 1544/1579 (97%), Gaps = 35/1579 (2%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 325
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 326 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 368
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 369 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 428
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 429 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 488
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 489 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 548
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 549 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 608
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRR
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRR 470
Query: 609 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 668
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 471 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 530
Query: 669 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 728
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 531 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 590
Query: 729 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 788
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 591 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 650
Query: 789 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 848
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 651 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 710
Query: 849 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 908
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 711 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 770
Query: 909 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 968
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 771 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 830
Query: 969 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 1028
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
Query: 1029 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 1088
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 891 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 950
Query: 1089 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1148
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 951 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1010
Query: 1149 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1208
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 1011 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1070
Query: 1209 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1268
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1071 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1130
Query: 1269 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1328
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1131 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1190
Query: 1329 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1388
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1191 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1250
Query: 1389 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1448
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1251 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1310
Query: 1449 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1508
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1311 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1370
Query: 1509 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1568
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1371 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1430
Query: 1569 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1628
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1431 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1490
Query: 1629 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1688
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1491 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1550
Query: 1689 SMRRLSRTSAFQSFESKHN 1707
SMRRLSRTSAFQSFESKHN
Sbjct: 1551 SMRRLSRTSAFQSFESKHN 1569
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 1462 bits (3786), Expect = 0.0
Identities = 737/1296 (56%), Positives = 961/1296 (74%), Gaps = 79/1296 (6%)
Query: 60 AQKSWIERAFYKRECVHIIPSTKDPHRCC-------------CGRLIGQHVGLTPSISVL 106
+QKSWIE KRECV+IIPS+KDPHRC CGRL+ QH T S+++
Sbjct: 2 SQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM- 60
Query: 107 QNEKNESRLSRNDIQS-EKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPD 165
+ ++ +L + Q+ E+WS+ KHT+ SPTDA+G I FQGG HS +A YVR+S+DTKP+
Sbjct: 61 --KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPE 118
Query: 166 LLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNT 225
++L L+ KEWQ+ELPKL+ISVHGG+Q FEL P++KQ+ GKGLIKAA+TTGAWI TGGVNT
Sbjct: 119 VILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNT 178
Query: 226 GVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVL 285
GV +HVGDALK+HAS+S KICTIGIAPWG++EN+ DL+GRDVV PYQT+ NP+SKL VL
Sbjct: 179 GVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVL 238
Query: 286 NSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVIS 345
N++HSHFIL D+GT GKYGAEV+LRR+LEK I+ Q+I+ RIGQGVPVVALI EGGPNVI
Sbjct: 239 NNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVIL 298
Query: 346 IVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTR 405
VLEYL+++PPVPVVVC+G+GRA+D+LA+ HK +EEGG + ++ ++ TI+KTF + +
Sbjct: 299 TVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQ 358
Query: 406 TQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWN 465
+A HLF LMECMK+KELITVF +GS+ HQDID+AILTALLKG NASA DQL L LAW+
Sbjct: 359 NEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWD 418
Query: 466 RVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELY 525
RVDIA++ +F+YGQQW VGSLEQAMLDALV+DRV FVKLLIENGVSMH+FLTI RLEELY
Sbjct: 419 RVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELY 478
Query: 526 NTRHGPSN-TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH 584
NT+ GP+N L+HLVRDVK+GNLPP Y+I+LIDIGLVIEYLMGG YRC YTRKRFR +Y+
Sbjct: 479 NTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYN 538
Query: 585 NLFG-------------PKRPKALKLLGMEDD--------------IPLRRGRKTT---- 613
+L G P+ K+ + G D P R T
Sbjct: 539 SLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEG 598
Query: 614 -KKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKL 672
KKR ++ +D+DDPE FP+P +EL++WA LMKRQ MA F WQHGEE+MAKALVACK+
Sbjct: 599 KKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKI 658
Query: 673 CKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSN 732
++MA+EA ++D+VDD S+EL S DFGQLAVELL+QS++QDE +AMKLLTYELKNWSN
Sbjct: 659 YRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSN 718
Query: 733 ATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKN 792
+TCL+LAV+++ R F+AHTC+QMLL+DMWMGRL MRKNS KVIL IL+PP+IL LE+K
Sbjct: 719 STCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKT 778
Query: 793 KDDMPYMSQAQEIHLQEKEAEEP--EKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQ 850
K +M ++ Q+Q+ H + E + T+E E + +L N G K+E E+Q
Sbjct: 779 KAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEG-----KNEMEIQ 833
Query: 851 SKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYI 910
K + +P+ RK Y FY+APIVKFWF TLAY+G+LML+ ++VLV+ME+ PS QEWIVI+YI
Sbjct: 834 MKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYI 893
Query: 911 FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRL---------Q 961
FT IEK+REI MSE GK+ QK+KVW +Y+N++D IAI+ F +G LR
Sbjct: 894 FTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAY 953
Query: 962 DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMS 1021
D GR+IYC+NII+WY+RLLD VN+ GPYVMMIGKM+ +M Y V+IM +VL+S
Sbjct: 954 DNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLS 1013
Query: 1022 FGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPP 1081
FGV R+AIL+P+E PSW LAK+I + PYWMI+GEV+A +ID D I Q+
Sbjct: 1014 FGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEID------VCANDSVIPQI-- 1065
Query: 1082 CKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHER 1141
C G W+ P + A YL V I++VNLLIA FNN + +VK+ISN VWK+QRY IM +HE+
Sbjct: 1066 CGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEK 1125
Query: 1142 PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEE 1201
PVLPPPLII SH+ +F +C R +K D+ G KLF+T+++ KK+HDFEEQC+E
Sbjct: 1126 PVLPPPLIILSHIVSLFCCICKRRKK-----DKTSDGPKLFLTEEDQKKLHDFEEQCVEM 1180
Query: 1202 YFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIG 1261
YF EKDD+F+S ++ERIRVT ERVE M ++++EV +R + +K SLQ++D ++ L+DL
Sbjct: 1181 YFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSA 1240
Query: 1262 RMATALERLTGLERAESNKIRSRTSSDCTDAAYIVR 1297
L+ LT + +E++K+ + + + + + ++ +
Sbjct: 1241 LTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQ 1276
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 1358 bits (3515), Expect = 0.0
Identities = 690/1278 (53%), Positives = 912/1278 (71%), Gaps = 77/1278 (6%)
Query: 53 PSVRLLKAQKSWIERAFYKRECVHIIPSTKDPHRCC-------------CGRLIGQHVGL 99
P + L++QKSWI+ F KREC IIPS+K+PHRC CGRLIG H G+
Sbjct: 5 PVLERLQSQKSWIKGVFDKRECSTIIPSSKNPHRCTPVCQVCQNLIRCYCGRLIGDHAGI 64
Query: 100 TPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVS 159
S ++ + ES E+WS+ KHT SPTD FGTI FQ G H++ A Y+R S
Sbjct: 65 DYSWTISAAKGKES---------EQWSVEKHTTKSPTDTFGTINFQDGEHTHHAKYIRTS 115
Query: 160 FDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIF 219
+DTK D LLHLM KEW++ELPKL+ISVHGG+QNF + K K++F +GL+KAA TTGAWI
Sbjct: 116 YDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETTGAWII 175
Query: 220 TGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPM 279
T G+NTGV +HVGDALK H+S S KI T+GI PWG++ENQ DLIG+DVV YQT+ NP+
Sbjct: 176 TEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQTLDNPL 235
Query: 280 SKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEG 339
SKLT LNSMHSHFIL+D+GT GKYG E+KLRR LEK++SLQKI+ R QGVPVV L+VEG
Sbjct: 236 SKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCRSRQGVPVVGLVVEG 295
Query: 340 GPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQK 399
GPNVI V E ++D PVVVC+G+GRA+D+LAF HK+ + G++ ++++++ IQ
Sbjct: 296 GPNVILSVWETVKDKD--PVVVCEGTGRAADLLAFTHKHLADEGMLRPQVKEEIICMIQN 353
Query: 400 TFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPDQLS 459
TF ++ Q++HLF ILMECM ++ IT+F SE QD+DLAILTALLKG N SA +QL+
Sbjct: 354 TFNFSLKQSKHLFQILMECMVHRDCITIFDADSEEQQDLDLAILTALLKGTNLSASEQLN 413
Query: 460 LALAWNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTIS 519
LA+AW+RVDIA+ I IY Q W +LEQAM DALV+DRVDFVKLLIE GV++HRFLTI
Sbjct: 414 LAMAWDRVDIAKKHILIYEQHWKPDALEQAMSDALVMDRVDFVKLLIEYGVNLHRFLTIP 473
Query: 520 RLEELYNTRHGPSNT-LYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKR 578
RLEELYNT+ GP+NT L+HLV+DVK+ L YRI+LIDIGLV+EYL+G AYR NYTRK
Sbjct: 474 RLEELYNTKQGPTNTLLHHLVQDVKQHTLLSGYRITLIDIGLVVEYLIGRAYRSNYTRKH 533
Query: 579 FRTLYHNLF----------GPKRPKALKLLG------------MEDDIPLRRGRKTTKKR 616
FR LY+NL+ G + A L E I L + RK K +
Sbjct: 534 FRALYNNLYRKYKHQRHSSGNRNESAESTLHSQFIRTAQPYKFKEKSIVLHKSRK--KSK 591
Query: 617 EEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAM 676
E+ V DDPE F +P+++L+VWAVLMKRQKMA+FFWQHGEEA KA++AC L +AM
Sbjct: 592 EQNVS---DDPESTGFLYPYNDLLVWAVLMKRQKMAMFFWQHGEEATVKAVIACILYRAM 648
Query: 677 AHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCL 736
AHEA E+ MVDD S+EL + S+ FGQLA++LL++++KQ+E++AM LLTYEL+NWSN+TCL
Sbjct: 649 AHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMAMTLLTYELRNWSNSTCL 708
Query: 737 QLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDM 796
+LAV+ R F++HTC+QMLLTDMWMGRL+MRKNS LK+I+ I+LPP+IL+LEFK+K +M
Sbjct: 709 KLAVSGGLRPFVSHTCTQMLLTDMWMGRLKMRKNSWLKIIISIILPPTILTLEFKSKAEM 768
Query: 797 PYMSQAQEIHLQEKEAEEPEKPTKEK---EEEDMELTAMLGRNNGESSRKKDEEEVQSKH 853
++ Q+Q+ +++ +KE +E D+E R + E + ++S H
Sbjct: 769 SHVPQSQDFQFMWYYSDQNASSSKESASVKEYDLE------RGHDEKLDENQHFGLESGH 822
Query: 854 RLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTL 913
+ +P RK+YEFY+APIVKFWFYT+AY+ +LMLF Y VLV+M+ PS QEW+V YIFT
Sbjct: 823 QHLPWTRKVYEFYSAPIVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVQEWLVSIYIFTN 882
Query: 914 GIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIY 973
IE +REI +SEPGK QKVKVW+ EYWN+T+ +AI LFS G +LR D PF + GR+IY
Sbjct: 883 AIEVVREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGFVLRWGDPPFHTAGRLIY 942
Query: 974 CVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN 1033
C++II+W+ RLLD F VN++ GPYV MI KM +M Y VIIM +VL+SFGVAR+AIL P
Sbjct: 943 CIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLSFGVARKAILSPK 1002
Query: 1034 EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIM 1093
E PSW LA++I + PYWMIYGEV+A +ID Q P C G+++ P +
Sbjct: 1003 EPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQ------------PSCPPGSFLTPFLQ 1050
Query: 1094 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 1153
A YL V I++VNLLIA FNN + +++SISN +WK+ RY+ IMT+HE+P LPPPLI+ SH
Sbjct: 1051 AVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTYHEKPWLPPPLILLSH 1110
Query: 1154 MTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSS 1213
+ ++ + LCC H D +E D GLKL+++ ++LKK+HDFEEQC+E+YF EK + N S
Sbjct: 1111 VGLLLRRLCCHRAPH--DQEEGDVGLKLYLSKEDLKKLHDFEEQCVEKYFHEKMEDVNCS 1168
Query: 1214 NDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGL 1273
+ERIRVTSERV M +L+E+NE+ +K SL ++D ++ L+DL L+ L+ +
Sbjct: 1169 CEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSALTVDTLKVLSAV 1228
Query: 1274 ERAESNK--IRSRTSSDC 1289
+ + ++ + R S C
Sbjct: 1229 DTLQEDEALLAKRKHSTC 1246
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 1234 bits (3192), Expect = 0.0
Identities = 684/1204 (56%), Positives = 829/1204 (68%), Gaps = 102/1204 (8%)
Query: 483 VGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV 542
V +LEQAMLDALVLDRVDFVKLLIENGV+M FLTI RLEELYNTR GP NTL+ LVRDV
Sbjct: 458 VNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDV 517
Query: 543 KKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMED 602
KK NLPPDY ISLIDIGLV+EYLMGGAYRCNYTRK FRTLY+NLFGPKRPKALKLLGMED
Sbjct: 518 KKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKALKLLGMED 577
Query: 603 DIPLRRGRKTTKKR-EEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEE 661
D P +G+K KK+ EEE+DID+DDP ++ F +PFHELMVWAVLMKRQKMA+F WQ GEE
Sbjct: 578 DEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEE 637
Query: 662 AMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMK 721
+MAKALVACKL KAMAHE+SE+D+VDDISQ+L++NS+DFGQLA+ELLDQSYK DEQ+AMK
Sbjct: 638 SMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMK 697
Query: 722 LLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILL 781
LLTYELKNWSN+TCL+LAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKN GLKVI+GILL
Sbjct: 698 LLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILL 757
Query: 782 PPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESS 841
PP+IL LEF+ DD Y + KE E+ KEKEEE+ + A G S
Sbjct: 758 PPTILFLEFRTYDDFSYQTS--------KENEDG----KEKEEENTDANADAG------S 799
Query: 842 RKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST 901
RK DEE K R IP+G KI EFYNAPIVKFWFYT++Y+GYL+LFNY++LV+M+ WPS
Sbjct: 800 RKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSL 859
Query: 902 QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ 961
QEWIVISYI +L +EK+REILMSEPGKL QK+KVWLQEYWN+TDL+AI F +G ILRLQ
Sbjct: 860 QEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQ 919
Query: 962 DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMS 1021
+QP+ GRVIYCV+II+WYIR+LDIFGVNKYLGPYVMMIGKMMIDM+YFV+IMLVVLMS
Sbjct: 920 NQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMS 979
Query: 1022 FGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID-------PPCGQNETREDG 1074
FGVARQAIL P E+PSWKLA+NIFYMPYWMIYGEVFADQID PPCG+N E+G
Sbjct: 980 FGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEG 1039
Query: 1075 KIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 1134
K +LPPC GAW+ PA+MACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL
Sbjct: 1040 K--RLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 1097
Query: 1135 IMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR-KHESDPDERDYGLKLFITDDELKKVHD 1193
IMTFH+RPVLPPP+II SH+ +I L R R K E D +ERD GLKLF++D+ELK++H+
Sbjct: 1098 IMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHE 1157
Query: 1194 FEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRL 1253
FEEQC++E+FREK+D SS+DERIRVTSERVENMSMRLEE+NERE MK SLQTVD+RL
Sbjct: 1158 FEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMKTSLQTVDLRL 1217
Query: 1254 AQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNT----- 1308
AQLE+L RM ALE L G++R++ + RSR SS+C +A Y++RQSS NS +G +
Sbjct: 1218 AQLEELSNRMVNALENLAGIDRSDLIQARSRASSEC-EATYLLRQSSINSADGYSLYRYH 1276
Query: 1309 FKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRAT 1368
F +E + E+T TSP R ++ SF KD + E SLH +
Sbjct: 1277 FNGEELL---FEDTSLSTSPGTGVRKKTCSFRIKEEKD-----VKTHLVPECQNSLHLSL 1328
Query: 1369 SSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGE 1428
+ + A PD H +D L N+ E
Sbjct: 1329 GTSTSA---------------TPDGS----------------HLAVDDLKNA-------E 1350
Query: 1429 PSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDS 1488
S P + T + + S S++ D+ +S + E N
Sbjct: 1351 ESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNTQLTVETTN---I 1407
Query: 1489 EPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSIT 1548
E + + +E +K +RY + +KS SF++S R V EY+SIT
Sbjct: 1408 EGTISYPLEETKITRYFPDE--TINACKTMKSRSFVYSRGRKLVGGVNQDV---EYSSIT 1462
Query: 1549 D---CIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGR 1605
D + +C + P + E + + + + EA R
Sbjct: 1463 DQQLTTEWQCQVQKITRSHSTDIP-----YIVSEAAVQAEHKEQFADMQDEHHVAEAIPR 1517
Query: 1606 RATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRN 1665
++++ + + E LS K ++ + + + + H R SI KLDR +
Sbjct: 1518 IPRLSLTITDRNGMENLLS-----VKPDQTLGFPSLRSKSLHGHPRNVKSIQGKLDRSGH 1572
Query: 1666 TASL 1669
+S+
Sbjct: 1573 ASSV 1576
Score = 651 bits (1679), Expect = 0.0
Identities = 310/406 (76%), Positives = 360/406 (88%), Gaps = 4/406 (0%)
Query: 82 KDPHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGT 141
KD +RCCCG+ QH+ PS + +NE+ ++ + Q EKWS++KHTQ PTD++G
Sbjct: 2 KDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQV---ETQPEKWSVAKHTQSYPTDSYGV 58
Query: 142 IEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ 201
+EFQGGG+SNKAMY+RVS+DTKPD LLHLM K+WQLELPKLLISVHGGLQNFE+QPKLKQ
Sbjct: 59 LEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQ 118
Query: 202 VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQE 261
VFGKGLIKAAMTTGAWIFTGGV+TGVI HVGDALKDH+SKSRG++C IGIAPWGIVEN+E
Sbjct: 119 VFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKE 178
Query: 262 DLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQK 321
DL+G+DV R YQTMSNP+SKL+VLN+ H+HFILADNGT GKYGAEVKLRR LEKHISLQK
Sbjct: 179 DLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQK 238
Query: 322 INTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEE 381
INTR+GQGVP+V L+VEGGPNV+SIVLEYL++ PP+PVV+CDGSGRASDIL+F HKY EE
Sbjct: 239 INTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEE 298
Query: 382 GGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLA 441
GG+INESLR+QLLVTIQKTF Y + Q+ LF I+MECMKKKEL+TVFRMGSEG QDI++A
Sbjct: 299 GGIINESLREQLLVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSEGQQDIEMA 358
Query: 442 ILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQW-PVGSL 486
ILTALLKG N SAPDQLSLALAWNRVDIARSQIF++G W P+GSL
Sbjct: 359 ILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSL 404
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 564 bits (1453), Expect = e-160
Identities = 405/1255 (32%), Positives = 634/1255 (50%), Gaps = 156/1255 (12%)
Query: 63 SWIERAFYKRECVHIIPSTK--DPHR--CCCGRLIGQHVGLTPSISVLQNEKNESRLSRN 118
SWI K+ECV+ + S+K D + C CG QH+ E +
Sbjct: 61 SWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHL--------------EEATKPH 106
Query: 119 DIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLE 178
Q +W KH Q PTDAFG I F G K YVRVS DT ++ HLMT+ W L+
Sbjct: 107 TFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKK-YVRVSQDTPSSVIYHLMTQHWGLD 165
Query: 179 LPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDH 238
+P LLISV GG +NF ++P+LK +F +GL+K A TTGAWI TGG +TGV++ VG+A++D
Sbjct: 166 VPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDF 225
Query: 239 ASKS---RGKICTIGIAPWGIVENQEDLIGRDVVRP--YQTMSNPMSKLTVLNSMHSHFI 293
+ S G++ TIG+A WG V +E LI P Y + LT L+S HSHFI
Sbjct: 226 SLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFI 285
Query: 294 LADNGTTGKYGAEVKLRRQLEKHISLQ-KINTRIGQGVPVVALIVEGGPNVISIVLEYLR 352
L D+GT G+YG E+ LR +LEK IS Q K + +P+V +++EGGP + +
Sbjct: 286 LVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDN--A 343
Query: 353 DTPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTF-TYTRTQAQHL 411
T P VV +GSGR +D++A I+ ++ +L V Q+ F T+T ++
Sbjct: 344 TTNGTPCVVVEGSGRVADVIAQVANLPVSDITIS-LIQQKLSVFFQEMFETFTESRIVEW 402
Query: 412 FIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAW 464
+ + +++++L+TVFR G +G QD+D+AIL ALLK + + QL LA+AW
Sbjct: 403 TKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAW 462
Query: 465 NRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEEL 524
NRVDIARS+IF+ QW L M AL+ ++ +FVKL +ENGV + F+T L L
Sbjct: 463 NRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYL 522
Query: 525 YNTRHGPSNTLYH------LVRDVKKGNLPPDY-RISLIDIGLVIEYLMGGAYRCNYTRK 577
Y + L+H LV D ++ P R+ + + V+ L+G + Y R
Sbjct: 523 YENLD--PSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRP 580
Query: 578 RFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFH 637
R L K L + G+ R K+ V +D P
Sbjct: 581 RHNDRLRLLLPVPHVK-LNVQGVSL-------RSLYKRSSGHVTFTMD---------PIR 623
Query: 638 ELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNS 697
+L++WA++ R+++A W ++ +A AL K+ K ++ E + D S+E+ +
Sbjct: 624 DLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDS----SEEMLALA 679
Query: 698 RDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLL 757
++ A+ + + Y++DE+ A KLLT + W TCLQLA+ AK F++H Q L
Sbjct: 680 EEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFL 739
Query: 758 TDMWMGRLRMRKNSGL-KVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPE 816
T +W G+L + ++GL +V L +L P +
Sbjct: 740 TKVWWGQLSV--DNGLWRVTLCMLAFPLL------------------------------- 766
Query: 817 KPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFY 876
LT ++ S R+K ++V + + F+ AP+V F
Sbjct: 767 ------------LTGLI------SFREKRLQDVGTP------AARARAFFTAPVVVFHLN 802
Query: 877 TLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGK--LLQKVK 934
L+Y +L LF Y+++V + PS E + ++F+L E+MR+ L +P + L++K
Sbjct: 803 ILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQ-LFYDPDECGLMKKAA 861
Query: 935 VWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYL 994
++ ++WN D+ AILLF G+ RL GRVI ++ I + +RL+ IF ++K L
Sbjct: 862 LYFSDFWNKLDVGAILLFVAGLTCRLIPATLYP-GRVILSLDFILFCLRLMHIFTISKTL 920
Query: 995 GPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYG 1054
GP ++++ +MM D+ +F+ ++ V ++SFGVA+QAIL NE L + Y Y I+G
Sbjct: 921 GPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFG 980
Query: 1055 EV--FADQID---PPCGQNETR-------EDGKIIQLPPCKTGAWIVPAIMACYLLVANI 1102
++ + D ++ C N T E Q P W+ ++ YLL NI
Sbjct: 981 QIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPE--WLTVLLLCLYLLFTNI 1038
Query: 1103 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLC 1162
LL+NLLIA+FN TF +V+ ++Q+WKFQR+ LI +H RP PPP I+ SH+ + + +
Sbjct: 1039 LLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVV 1098
Query: 1163 CRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTS 1222
+ P +R LK + +E + +E E Y + + + +++I S
Sbjct: 1099 LK------TPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDIS 1152
Query: 1223 ERVENMSMRLE-EVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERA 1276
+V+ M L+ + +R SM+ RLA LE+ + + A AL + RA
Sbjct: 1153 NKVDAMVDLLDLDPLKRSGSMEQ-------RLASLEEQVAQTARALHWIVRTLRA 1200
>gi|21314671 transient receptor potential cation channel, subfamily M,
member 4 [Homo sapiens]
Length = 1214
Score = 507 bits (1306), Expect = e-143
Identities = 378/1256 (30%), Positives = 629/1256 (50%), Gaps = 114/1256 (9%)
Query: 61 QKSWIERAFYKRECVHIIPSTKDPHR--CCCGRLIGQHVGLTPSISVLQNEKNESRLSRN 118
++SWI + F K+ C I + DP C CGR H P++++ E
Sbjct: 7 EQSWIPKIFKKKTCTTFIVDSTDPGGTLCQCGRPRTAH----PAVAM------EDAFGAA 56
Query: 119 DIQSEKWSISKHTQLSPTDAFGTIEFQGGG--HSNKAMYVRVSFDTKPDLLLHLMTKEWQ 176
+ W HT PTDA+G ++F G G HSN ++R+S T P + L+T+ W
Sbjct: 57 VVTV--WDSDAHTTEKPTDAYGELDFTGAGRKHSN---FLRLSDRTDPAAVYSLVTRTWG 111
Query: 177 LELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK 236
P L++SV GG LQ L+ + +GL++AA +TGAWI TGG++TG+ RHVG A++
Sbjct: 112 FRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVR 171
Query: 237 DHASKSRG--KICTIGIAPWGIVENQEDLIGRDVVRP--YQTMSNPMSKLTV-LNSMHSH 291
DH S G K+ +G+APWG+V N++ LI P Y+ +P + L+ +S
Sbjct: 172 DHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSA 231
Query: 292 FILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-IGQGVPVVALIVEGGPNVISIVLEY 350
F L D+GT G G E + R +LE +IS QK G +PV+ L+++G +++ +
Sbjct: 232 FFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENA 291
Query: 351 LRDTPPVPVVVCDGSGRASDILAFGHKYS---EEGGLINESLRDQLLVTIQKTFTYTRTQ 407
+ +P ++ GSG A+D LA + + GG RD++ + F + +
Sbjct: 292 TQ--AQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRI-----RRF-FPKGD 343
Query: 408 AQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALA 463
+ L + M +KEL+TV+ +G ++ + +L AL+K +S D+L LA+A
Sbjct: 344 LEVLQAQVERIMTRKELLTVYS-SEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVA 402
Query: 464 WNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEE 523
WNRVDIA+S++F QW LE +++DAL+ DR +FV+LLI +G+S+ FLT RL +
Sbjct: 403 WNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQ 462
Query: 524 LYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGA--YRCNYTRKRFRT 581
LY+ PSN+L + D + G L GGA R R
Sbjct: 463 LYSA--APSNSLIRNLLDQASHSA-----------GTKAPALKGGAAELRPPDVGHVLRM 509
Query: 582 LYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLD-DPEINHFPFPFHELM 640
L + P+ P G D P + ++ ++ L D + P+ +L+
Sbjct: 510 LLGKMCAPRYPSG----GAWDPHPGQGFGESMYLLSDKATSPLSLDAGLGQAPWS--DLL 563
Query: 641 VWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH---EASENDMVDDISQELNHNS 697
+WA+L+ R +MA++FW+ G A++ AL AC L + MA +A E D++ +
Sbjct: 564 LWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFK----- 618
Query: 698 RDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLL 757
F + V+L + Y+ E A +LL W +ATCLQLA+ A R F A Q LL
Sbjct: 619 --FEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLL 676
Query: 758 TDMWMGRLRMRKNSGLKVILGILLPPSILS--LEFKNKDDMPYMSQAQEIHLQEKEAEEP 815
T W G + ++L PP I + + F+ ++ P + + E P
Sbjct: 677 TQKWWGDMASTTPIWA-LVLAFFCPPLIYTRLITFRKSEEEPTREELEFDMDSVINGEGP 735
Query: 816 EKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWF 875
E+ + + GR R + R+ + F+ AP+ F
Sbjct: 736 VGTADPAEKTPLGVPRQSGRPGCCGGRCGGRRCL----------RRWFHFWGAPVTIFMG 785
Query: 876 YTLAYIGYLMLFNYIVLVKMERWP-STQEWIVISYIFTLGIEKMREILMSEPGKLL---- 930
++Y+ +L+LF+ ++LV + P + E ++ + FTL E++R+ L G L
Sbjct: 786 NVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGGGGSLASGGP 845
Query: 931 --------QKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYI 982
Q+++++L + WN DL+A+ F +G+ RL + GR + C++ + + +
Sbjct: 846 GPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHL-GRTVLCIDFMVFTV 904
Query: 983 RLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAK 1042
RLL IF VNK LGP ++++ KMM D+ +F+ + V L+++GVA + +L P + + +
Sbjct: 905 RLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILR 964
Query: 1043 NIFYMPYWMIYGEVFADQIDPPCGQ--NETREDGKIIQLPPCKTGA-------WIVPAIM 1093
+FY PY I+G++ + +D + N + E G P + G W+V ++
Sbjct: 965 RVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLL 1024
Query: 1094 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 1153
+LLVANILLVNLLIA+F+ TF +V+ S+ WK QRY+LI FH RP L PP I+ SH
Sbjct: 1025 VIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISH 1084
Query: 1154 MTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSS 1213
+ ++ + LC R R + ++ +++++ + +K+ +E E + + S
Sbjct: 1085 LRLLLRQLCRRPRSPQPSSPALEH-FRVYLSKEAERKLLTWESVHKENFLLARARDKRES 1143
Query: 1214 NDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALER 1269
+ ER++ TS++V+ +L + E E +K ++ + Q ++G +A AL R
Sbjct: 1144 DSERLKRTSQKVDLALKQLGHIREYEQRLK----VLEREVQQCSRVLGWVAEALSR 1195
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 470 bits (1209), Expect = e-132
Identities = 349/1160 (30%), Positives = 569/1160 (49%), Gaps = 138/1160 (11%)
Query: 140 GTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKL 199
G + F G G + +VRV P +L L+ EW L P L++S+ G Q F ++ L
Sbjct: 26 GEVNFGGSG-KKRGKFVRVPSGVAPSVLFDLLLAEWHLPAPNLVVSLVGEEQPFAMKSWL 84
Query: 200 KQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDHA---SKSRGKICTIGIAPWGI 256
+ V KGL+KAA +TGAWI T + G+ RHVG A++DH+ + ++ ++ +G+A G
Sbjct: 85 RDVLRKGLVKAAQSTGAWILTSALRVGLARHVGQAVRDHSLASTSTKVRVVAVGMASLGR 144
Query: 257 V-------ENQEDLIGRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKL 309
V E QED V + L L+S SHFIL + G GK +L
Sbjct: 145 VLHRRILEEAQEDF----PVHYPEDDGGSQGPLCSLDSNLSHFILVEPGPPGKGDGLTEL 200
Query: 310 RRQLEKHISLQKINTRIGQG------VPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCD 363
R +LEKHIS Q R G G +PV+ L+V G PN + + + P ++V
Sbjct: 201 RLRLEKHISEQ----RAGYGGTGSIEIPVLCLLVNGDPNTLERISRAVEQAAPWLILV-- 254
Query: 364 GSGRASDILAFGHKYSEEGGLINESLRDQLLV--TIQKTFTYTRTQAQHLFI-------- 413
GSG +D+LA L+N+ LLV +K F + ++H
Sbjct: 255 GSGGIADVLA---------ALVNQP---HLLVPKVAEKQFK-EKFPSKHFSWEDIVRWTK 301
Query: 414 ILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP------DQLSLALAWNRV 467
+L + L+TV+ EG +++D IL AL+K + + D+L LA+AW+RV
Sbjct: 302 LLQNITSHQHLLTVYDFEQEGSEELDTVILKALVKACKSHSQEPQDYLDELKLAVAWDRV 361
Query: 468 DIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNT 527
DIA+S+IF +W LE+ M+DALV ++ +FV+L ++NG + FLT RL+ELY +
Sbjct: 362 DIAKSEIFNGDVEWKSCDLEEVMVDALVSNKPEFVRLFVDNGADVADFLTYGRLQELYRS 421
Query: 528 RHGPSNTLYHLVRDVKKGNL----------------PPDYRISLIDIGLVIEYLMGGAYR 571
S L R ++ L PP + SL ++ V++ + A R
Sbjct: 422 VSRKSLLFDLLQRKQEEARLTLAGLGTQQAREPPAGPPAF--SLHEVSRVLKDFLQDACR 479
Query: 572 CNYTRKRFRTLYHNLFGP-KRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEIN 630
Y R GP KRP K L +DL+ N
Sbjct: 480 GFYQDGRPGDRRRAEKGPAKRPTGQKWL-----------------------LDLNQKSEN 516
Query: 631 HFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDIS 690
P+ +L +WAVL R +MA +FW G+E +A AL ACK+ K M+H +E +
Sbjct: 517 ----PWRDLFLWAVLQNRHEMATYFWAMGQEGVAAALAACKILKEMSHLETEAEAARATR 572
Query: 691 QELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAH 750
+ + +LA++L + Y E A LL + WS TCL LA A + F AH
Sbjct: 573 EA------KYERLALDLFSECYSNSEARAFALLVRRNRCWSKTTCLHLATEADAKAFFAH 626
Query: 751 TCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKN-KDDMPYMSQAQEIHLQE 809
Q LT +W G M + + +LG L P+++ ++ P + ++ LQ+
Sbjct: 627 DGVQAFLTRIWWGD--MAAGTPILRLLGAFLCPALVYTNLITFSEEAPLRTGLED--LQD 682
Query: 810 KEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAP 869
++ + EK + +E R G+ R + L + +F+ AP
Sbjct: 683 LDSLDTEKSPLYGLQSRVEELVEAPRAQGDRGP-----------RAVFLLTRWRKFWGAP 731
Query: 870 IVKFWFYTLAYIGYLMLFNYIVLVKME---RWPSTQEWIVISYIFTLGIEKMRE-ILMSE 925
+ F + Y +L LF Y++LV + PS E + ++FTL +E++R+ E
Sbjct: 732 VTVFLGNVVMYFAFLFLFTYVLLVDFRPPPQGPSGPEVTLYFWVFTLVLEEIRQGFFTDE 791
Query: 926 PGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLL 985
L++K +++ + WN D++AI LF VG+ R+ F + GR + ++ + + +RL+
Sbjct: 792 DTHLVKKFTLYVGDNWNKCDMVAIFLFIVGVTCRMLPSAFEA-GRTVLAMDFMVFTLRLI 850
Query: 986 DIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIF 1045
IF ++K LGP ++++ +MM D+ +F+ + V L+++GV QA+L P++ + + +
Sbjct: 851 HIFAIHKQLGPKIIVVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVL 910
Query: 1046 YMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKT--GAWIVPAIMACYLLVANIL 1103
Y PY I+G++ D+ID N + + P C + W+V ++ +LLV N+L
Sbjct: 911 YRPYLQIFGQIPLDEIDE-ARVNCSTHPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVL 969
Query: 1104 LVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCC 1163
L+NLLIA+F+ TF V+ ++ WKFQRY LI+ +HERP L PP I+ SH+++ + +
Sbjct: 970 LMNLLIAMFSYTFQVVQGNADMFWKFQRYNLIVEYHERPALAPPFILLSHLSLTLRRVFK 1029
Query: 1164 RWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSE 1223
+ +H+ + ERD + D +KV +E E + + + R S E +R T+
Sbjct: 1030 KEAEHKREHLERD------LPDPLDQKVVTWETVQKENFLSKMEKRRRDSEGEVLRKTAH 1083
Query: 1224 RVENMSMRLEEVNEREHSMK 1243
RV+ ++ L + E+E +K
Sbjct: 1084 RVDFIAKYLGGLREQEKRIK 1103
>gi|45935368 transient receptor potential cation channel, subfamily
M, member 3 isoform h [Homo sapiens]
Length = 230
Score = 464 bits (1194), Expect = e-130
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 333
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQGVPVV 180
Query: 334 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 383
ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG
Sbjct: 181 ALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG 230
>gi|55953096 transient receptor potential cation channel, subfamily
M, member 3 isoform c [Homo sapiens]
Length = 255
Score = 450 bits (1158), Expect = e-126
Identities = 230/255 (90%), Positives = 230/255 (90%), Gaps = 25/255 (9%)
Query: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 325
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 326 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 368
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 369 SDILAFGHKYSEEGG 383
SDILAFGHKYSEEGG
Sbjct: 241 SDILAFGHKYSEEGG 255
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 322 bits (824), Expect = 3e-87
Identities = 226/741 (30%), Positives = 363/741 (48%), Gaps = 96/741 (12%)
Query: 63 SWIERAFYKRECVHIIPSTKDPHRCC-CGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQ 121
++I+ F KRECV +K C CG QH+ T Q
Sbjct: 43 NFIQANFKKRECVFFTKDSKATENVCKCGYAQSQHMEGTQIN-----------------Q 85
Query: 122 SEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQLELPK 181
SEKW+ KHT+ PTDAFG I+F+ G K Y+R+S DT ++L L+T+ W L+ P
Sbjct: 86 SEKWNYKKHTKEFPTDAFGDIQFETLGKKGK--YIRLSCDTDAEILYELLTQHWHLKTPN 143
Query: 182 LLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKDH--A 239
L+ISV GG +NF L+P+++++F + LI A + GAWI TGG + G+++++G+ ++D+ +
Sbjct: 144 LVISVTGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTIS 202
Query: 240 SKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMSNPMSKLT-----VLNSMHSHFIL 294
S I IGIA WG+V N++ LI Y M T +L++ H+H +L
Sbjct: 203 RSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGYFLAQYLMDDFTRDPLYILDNNHTHLLL 262
Query: 295 ADNGTTGKYGAEVKLRRQLEKHISLQKI-NTRIGQGVPVVALIVEGGPNVISIVLEYLRD 353
DNG G E KLR QLEK+IS + I ++ G +P+V GG + + +++
Sbjct: 263 VDNGCHGHPTVEAKLRNQLEKYISERTIQDSNYGGKIPIVCFAQGGGKETLKAINTSIKN 322
Query: 354 TPPVPVVVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFI 413
+P VV +GSG+ +D++A E L + +++++L+ + +T + + +I
Sbjct: 323 K--IPCVVVEGSGQIADVIA--SLVEVEDALTSSAVKEKLVRFLPRTVSRLPEEETESWI 378
Query: 414 I-LMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAPD------QLSLALAWNR 466
L E ++ L+TV +M G + + AI AL K + S D QL L L WN+
Sbjct: 379 KWLKEILECSHLLTVIKMEEAGDEIVSNAISYALYKAFSTSEQDKDNWNGQLKLLLEWNQ 438
Query: 467 VDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYN 526
+D+A +IF ++W L++ M AL+ DR FV+L +ENG+++ +FLT L EL++
Sbjct: 439 LDLANDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLRKFLTHDVLTELFS 498
Query: 527 TRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNL 586
S +Y ++ K S D L + + +R
Sbjct: 499 NHF--STLVYRNLQIAKN---------SYNDALLTFVWKLVANFR--------------- 532
Query: 587 FGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDD--PEINHFPFPFHELMVWAV 644
R RK + +E+DI+L D P H P L +WA+
Sbjct: 533 --------------------RGFRKEDRNGRDEMDIELHDVSPITRH---PLQALFIWAI 569
Query: 645 LMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLA 704
L +++++ W+ AL A KL K +A ++ + + S+EL + ++ A
Sbjct: 570 LQNKKELSKVIWEQTRGCTLAALGASKLLKTLAKVKNDINAAGE-SEEL---ANEYETRA 625
Query: 705 VELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGR 764
VEL + Y DE LA +LL Y + W + CL+LAV A + FIA Q L+ W G
Sbjct: 626 VELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGE 685
Query: 765 LRMRKNSGLKVILGILLPPSI 785
+ R K+IL + + P +
Sbjct: 686 I-SRDTKNWKIILCLFIIPLV 705
Score = 172 bits (435), Expect = 3e-42
Identities = 109/370 (29%), Positives = 193/370 (52%), Gaps = 32/370 (8%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMS 924
F+ +P V F + + YI +L+LF Y++L+ P E ++ S +F L +++R+ ++
Sbjct: 730 FFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVN 789
Query: 925 EPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRS--DGRVIYCVNIIYWYI 982
+ + WNV D + + F G++ RL S GRVI+C++ I + +
Sbjct: 790 GVN--------YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTL 841
Query: 983 RLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAK 1042
RL+ IF V++ LGP ++M+ +M+ID+ +F+ + V +++FGVARQ IL NE+ + +
Sbjct: 842 RLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFR 901
Query: 1043 NIFYMPYWMIYGEVFADQID------PPCGQNETREDGKIIQLPP---CKTGAWIVPAIM 1093
++ Y PY ++G+V +D +D C ++L + WI ++
Sbjct: 902 SVIYEPYLAMFGQVPSD-VDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLV 960
Query: 1094 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 1153
Y+L NILLVNLL+A+F T V+ ++QVWKFQRY L+ + R +P P I+F++
Sbjct: 961 CIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAY 1020
Query: 1154 MTMIFQ---HLCCRWRKHES------DPDERDYGLKLFITDDELKKVHDFEEQCIEEY-- 1202
M+ + CC+ + ES + D + + ++ L K++ EE
Sbjct: 1021 FYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRH 1080
Query: 1203 -FREKDDRFN 1211
FR+ D + N
Sbjct: 1081 RFRQLDTKLN 1090
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
Query: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1179
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
Query: 1180 KLFITDDELKKVHDFEE 1196
D L++ H ++E
Sbjct: 519 IGRRAADNLRRHHQYQE 535
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1179
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1180 KLFITDDELKKVHDFEE 1196
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 687 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 739
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 740 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 782
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1179
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1180 KLFITDDELKKVHDFEE 1196
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 687 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 739
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 740 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 782
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|7706747 transient receptor potential cation channel, subfamily C,
member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1179
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1180 KLFITDDELKKVHDFEE 1196
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 687 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 739
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 740 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 782
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 78.2 bits (191), Expect = 6e-14
Identities = 71/343 (20%), Positives = 150/343 (43%), Gaps = 67/343 (19%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLC 1162
KF R +L M++ E V+P P ++ + I+ HLC
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLC 678
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 687 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 739
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 740 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 782
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|6912736 transient receptor potential cation channel, subfamily C,
member 5 [Homo sapiens]
Length = 973
Score = 71.2 bits (173), Expect = 8e-12
Identities = 76/360 (21%), Positives = 154/360 (42%), Gaps = 77/360 (21%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L + +IV + P+ EW+++ ++ +
Sbjct: 359 FIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGE 418
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGR------- 970
++E M + G ++ ++WN+ D L+ + L++ + R
Sbjct: 419 IKE--MWDGG-----FTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEM 471
Query: 971 --------VIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ ++ I +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 472 WHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 531
Query: 1023 GVARQAILF---------PNEEPSWKLAK--NIF-------YMPYWMIYG--EVFADQID 1062
+ F PN + K N F +W ++G ++ +
Sbjct: 532 ANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 1063 PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 1122
++E E ++ + Y +++ ++L+N+LIA+ NN++ +
Sbjct: 592 ---ARHEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 634
Query: 1123 SNQVWKFQRYQLIMT-FHERPVLPPPLII------FSHMTMIFQHLCCRWRKHESDPDER 1175
++ WKF R +L M+ F E LPPP I F ++ F + C R DPD R
Sbjct: 635 ADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKR----DPDGR 690
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 4e-09
Identities = 60/310 (19%), Positives = 135/310 (43%), Gaps = 60/310 (19%)
Query: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTF-FEVKSISNQV 1126
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ +
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRAADNL 635
Query: 1127 WKFQRYQLIM 1136
+ +YQ +M
Sbjct: 636 RRHHQYQEVM 645
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 687 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 739
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 740 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 782
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|9966865 transient receptor potential cation channel, subfamily C,
member 7 [Homo sapiens]
Length = 862
Score = 57.0 bits (136), Expect = 2e-07
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 961 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 1016
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
Query: 1017 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 1070
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
Query: 1071 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 1130
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
Query: 1131 RYQLIMT-FHERPVLPPP 1147
R +L ++ F E LP P
Sbjct: 691 RAKLWLSYFDEGRTLPAP 708
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 932 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 986
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 569 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 628
Query: 987 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 1042
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 629 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 688
Query: 1043 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 1102
F +W I+G + + D K I+ I + Y + +
Sbjct: 689 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 733
Query: 1103 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 1147
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 734 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 779
Score = 32.7 bits (73), Expect = 3.1
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 856 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 914
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 641 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 700
Query: 915 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 957
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 701 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 743
>gi|4507687 transient receptor potential cation channel, subfamily C,
member 3 isoform b [Homo sapiens]
Length = 848
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 932 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 986
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 496 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 555
Query: 987 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 1042
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 556 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 615
Query: 1043 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 1102
F +W I+G + + D K I+ I + Y + +
Sbjct: 616 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 660
Query: 1103 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 1147
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 661 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 706
Score = 32.7 bits (73), Expect = 3.1
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 856 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 914
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 568 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 627
Query: 915 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 957
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 628 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 670
>gi|5730102 transient receptor potential cation channel, subfamily C,
member 6 [Homo sapiens]
Length = 931
Score = 54.3 bits (129), Expect = 1e-06
Identities = 70/349 (20%), Positives = 133/349 (38%), Gaps = 89/349 (25%)
Query: 900 STQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR 959
S E ++IS++ + + +EI P K +L E WN+ D + +F+ I R
Sbjct: 492 SWMEMLIISWVIGMIWAECKEIWTQGP-------KEYLFELWNMLDFGMLAIFAASFIAR 544
Query: 960 LQ-------------------------------------------DQPFRSDGRVIYCVN 976
D S+G +Y +
Sbjct: 545 FMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEG--LYAIA 602
Query: 977 IIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGV-----------A 1025
++ + R+ I N+ GP + +G+ + D+ F++I ++V ++F + A
Sbjct: 603 VVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA 662
Query: 1026 RQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTG 1085
+Q F E S+K +W I+G + G ++
Sbjct: 663 KQNEAFTTVEESFKTL-------FWAIFGLSEVKSVVINYNHKFIENIGYVLY------- 708
Query: 1086 AWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVL 1144
Y + I+L+N+LIA+ N++F E++ ++ WKF R +L + F E L
Sbjct: 709 --------GVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTL 760
Query: 1145 PPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHD 1193
P P + +F +L + +K S+ + K F D E+ K+++
Sbjct: 761 PVPFNLVPSPKSLF-YLLLKLKKWISELFQGH--KKGFQEDAEMNKINE 806
Score = 36.6 bits (83), Expect = 0.21
Identities = 21/103 (20%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 856 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM-ERWPSTQEWIVISYIFTLG 914
I LGR + + + ++ + IG L++Y + K E + + +E + G
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFG 684
Query: 915 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 957
+ +++ ++++ K ++ + L +NVT +I +L + MI
Sbjct: 685 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMI 727
>gi|21314682 transient receptor potential cation channel, subfamily V,
member 6 [Homo sapiens]
Length = 725
Score = 52.8 bits (125), Expect = 3e-06
Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 994 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 1052
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P +L Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPE-ELGHFYDYPMALFS 532
Query: 1053 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 1112
E+F ID P N + LP ++ A + ++A +L++NLLIA+
Sbjct: 533 TFELFLTIIDGPANYN--------VDLP------FMYSITYAAFAIIATLLMLNLLIAMM 578
Query: 1113 NNTFFEVKSISNQVWKFQ 1130
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAHERDELWRAQ 596
>gi|17505200 transient receptor potential cation channel, subfamily V,
member 5 [Homo sapiens]
Length = 729
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 994 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 1052
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P+ L + Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPT-SLGQFYDYPMALFT 532
Query: 1053 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 1112
E+F ID P + + LP ++ + + ++A +L++NL IA+
Sbjct: 533 TFELFLTVIDAPANYD--------VDLP------FMFSIVNFAFAIIATLLMLNLFIAMM 578
Query: 1113 NNTFFEVKSISNQVWKFQ 1130
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAQERDELWRAQ 596
>gi|4507685 transient receptor potential cation channel, subfamily C,
member 1 [Homo sapiens]
Length = 759
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 867 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 924
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
Query: 925 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 968
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
Query: 969 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 1028
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
Query: 1029 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 1069
+ + ++E K IF + +W I+ E
Sbjct: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
Query: 1070 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 1129
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
Query: 1130 QRYQLIMT-FHERPVLPPPLII 1150
R +L ++ F ++ LPPP I
Sbjct: 629 ARAKLWLSYFDDKCTLPPPFNI 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,577,978
Number of Sequences: 37866
Number of extensions: 3037187
Number of successful extensions: 14187
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 13406
Number of HSP's gapped (non-prelim): 699
length of query: 1707
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1591
effective length of database: 13,855,062
effective search space: 22043403642
effective search space used: 22043403642
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.