Search of human proteins with 153945711

Search of human proteins with 153945711

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153945711 inter-alpha trypsin inhibitor heavy chain
precursor 5 isoform 2 [Homo sapiens]
         (742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor...  1499   0.0  
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor...  1490   0.0  
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ...   922   0.0  
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ...   419   e-117
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...   409   e-114
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]       379   e-105
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]   308   9e-84
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]        304   2e-82
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...    68   4e-11
gi|218505703 von Willebrand factor A domain containing 3A [Homo ...    50   8e-06
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    47   5e-05
gi|110578649 cache domain containing 1 [Homo sapiens]                  45   2e-04
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun...    44   5e-04
gi|118918435 von Willebrand factor A domain containing 3B [Homo ...    43   0.001
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo...    36   0.11 
gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]     35   0.19 
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                 35   0.33 
gi|34452173 integrin alpha X precursor [Homo sapiens]                  33   0.96 
gi|239749207 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  
gi|239508971 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          32   2.1  
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          32   2.1  
gi|4826988 ribosomal protein L3-like [Homo sapiens]                    30   6.2  
gi|30578412 potassium channel tetramerisation domain containing ...    30   8.1  

>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 2 [Homo sapiens]
          Length = 742

 Score = 1499 bits (3880), Expect = 0.0
 Identities = 742/742 (100%), Positives = 742/742 (100%)

Query: 1   MRNYDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQ 60
           MRNYDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQ
Sbjct: 1   MRNYDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQ 60

Query: 61  VLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSII 120
           VLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSII
Sbjct: 61  VLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSII 120

Query: 121 GFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIG 180
           GFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIG
Sbjct: 121 GFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIG 180

Query: 181 DRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLEN 240
           DRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLEN
Sbjct: 181 DRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLEN 240

Query: 241 CGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIII 300
           CGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIII
Sbjct: 241 CGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIII 300

Query: 301 AGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIE 360
           AGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIE
Sbjct: 301 AGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIE 360

Query: 361 RLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLE 420
           RLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLE
Sbjct: 361 RLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLE 420

Query: 421 EAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLT 480
           EAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLT
Sbjct: 421 EAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLT 480

Query: 481 VCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERS 540
           VCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERS
Sbjct: 481 VCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERS 540

Query: 541 YLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYK 600
           YLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYK
Sbjct: 541 YLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYK 600

Query: 601 KPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEG 660
           KPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEG
Sbjct: 601 KPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEG 660

Query: 661 PEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDT 720
           PEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDT
Sbjct: 661 PEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDT 720

Query: 721 WPGNVQGALKLAALKMQVHEGQ 742
           WPGNVQGALKLAALKMQVHEGQ
Sbjct: 721 WPGNVQGALKLAALKMQVHEGQ 742


>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 1 [Homo sapiens]
          Length = 956

 Score = 1490 bits (3857), Expect = 0.0
 Identities = 738/738 (100%), Positives = 738/738 (100%)

Query: 5   DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 64
           DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG
Sbjct: 219 DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 278

Query: 65  YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 124
           YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN
Sbjct: 279 YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 338

Query: 125 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 184
           RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV
Sbjct: 339 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 398

Query: 185 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 244
           SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT
Sbjct: 399 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 458

Query: 245 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 304
           RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL
Sbjct: 459 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 518

Query: 305 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 364
           VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS
Sbjct: 519 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 578

Query: 365 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 424
           YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG
Sbjct: 579 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 638

Query: 425 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFN 484
           MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFN
Sbjct: 639 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFN 698

Query: 485 IDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEI 544
           IDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEI
Sbjct: 699 IDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEI 758

Query: 545 TPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAP 604
           TPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAP
Sbjct: 759 TPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAP 818

Query: 605 FQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAV 664
           FQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAV
Sbjct: 819 FQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAV 878

Query: 665 LTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDTWPGN 724
           LTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDTWPGN
Sbjct: 879 LTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLAFHPFDTGMDTWPGN 938

Query: 725 VQGALKLAALKMQVHEGQ 742
           VQGALKLAALKMQVHEGQ
Sbjct: 939 VQGALKLAALKMQVHEGQ 956


>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 3 [Homo sapiens]
          Length = 702

 Score =  922 bits (2382), Expect = 0.0
 Identities = 461/462 (99%), Positives = 461/462 (99%)

Query: 5   DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 64
           DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG
Sbjct: 219 DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 278

Query: 65  YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 124
           YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN
Sbjct: 279 YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 338

Query: 125 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 184
           RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV
Sbjct: 339 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 398

Query: 185 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 244
           SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT
Sbjct: 399 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 458

Query: 245 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 304
           RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL
Sbjct: 459 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 518

Query: 305 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 364
           VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS
Sbjct: 519 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 578

Query: 365 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 424
           YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG
Sbjct: 579 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 638

Query: 425 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDG 466
           MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSV G
Sbjct: 639 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVRG 680


>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
           sapiens]
          Length = 946

 Score =  419 bits (1077), Expect = e-117
 Identities = 251/719 (34%), Positives = 390/719 (54%), Gaps = 46/719 (6%)

Query: 13  VINQNETFANIIFKPTVVQQARIAQN----GILGDFIIRYDVNREQSIGDIQVLNGYFVH 68
           VI++ +  A++ FKPTV QQ RI  N     + G+ ++ YDV RE+  G+++V NGYFVH
Sbjct: 239 VISKGQQKAHVSFKPTVAQQ-RICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVH 297

Query: 69  YFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV 128
           +FAP +L P+PKN++FV+D S SM G K++QT +A+ TIL DLR +D FS+I F+  I+ 
Sbjct: 298 FFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRT 357

Query: 129 WKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIV 188
           W++ LIS T   + D K YI  + P+GGT+IN AL RAI +LN+      +   SVSLI+
Sbjct: 358 WRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLII 417

Query: 189 FLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVH 248
            ++DG PTVGE    KI  N +E  +  + +F++G+G DVD+  L++LS EN G+ +R++
Sbjct: 418 LVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIY 477

Query: 249 EEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRK 308
             +D  SQL  FY+++ TPLL +++ +YP +SV   T+  F NYF GSEI++AGK    K
Sbjct: 478 GNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAK 537

Query: 309 LDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTT 368
           LD +   +TA+++   ++L+T   +      +D         D   D +   +LW+YLT 
Sbjct: 538 LDQIESVITATSANTQLVLET---LAQMDDLQDFLSK-----DKHADPDFTRKLWAYLTI 589

Query: 369 KELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAA 428
            +LL+    +     K R+ +    +++ +  +TP TS+ +         L +A     +
Sbjct: 590 NQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPS 649

Query: 429 -------MGPEPVVQSVRG-AGTQPGPLLKKPYQPRIKISKT------SVDGDPHFVVDF 474
                   G + V  S    A   P P++    Q    +  T       V+ DPHF++  
Sbjct: 650 CCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYL 709

Query: 475 PLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILI 534
           P S+  +CFNID +PG IL LVSD  +SG+ VNG+L+GA  P NG  K  TY   +    
Sbjct: 710 PKSQKNICFNIDSEPGKILNLVSD-PESGIVVNGQLVGAKKPNNG--KLSTYFGKLGFYF 766

Query: 535 NKPERSYLEITPSRVILD-GGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFV 593
            + E   +EI+   + L  G     L  + +  V +  +++SV     VT+T+   ++F 
Sbjct: 767 -QSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFS 825

Query: 594 ILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPL 653
           +L+H   K  P     LG YI  +   S   HGL+GQF+ +          P  ++ +  
Sbjct: 826 VLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQE----------PKIHIFNER 875

Query: 654 LLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDY 708
             +  E PEA + VKG ++ +    +K Y  +      + CWF  N+    IDG YKDY
Sbjct: 876 PGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDY 934


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score =  409 bits (1052), Expect = e-114
 Identities = 246/707 (34%), Positives = 374/707 (52%), Gaps = 63/707 (8%)

Query: 22  NIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPL 78
           ++ FKP++ QQ        + + GDF I YDVNRE S G++Q++NGYFVH+FAP+ LP +
Sbjct: 223 HVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRE-SPGNVQIVNGYFVHFFAPQGLPVV 281

Query: 79  PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 138
           PKNV FV+D S SM G KL QTK+AL  IL D++ +D  + I FS  +  WK+HL+  TP
Sbjct: 282 PKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATP 341

Query: 139 DSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVG 198
           +++++ + ++  M   G T+IN  L R I +LNK      I +RS S+++ LTDG   VG
Sbjct: 342 ENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVG 401

Query: 199 ETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLI 258
           E+   KI  N R A  G+  ++ +G GN++++  LE ++LEN G  RR++E+ DA  QL 
Sbjct: 402 ESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQ 461

Query: 259 GFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTA 318
           GFY+E+  PLL+ + ++YP ++++  T+  + ++++GSEI++AG+LVD  ++    +V  
Sbjct: 462 GFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKG 521

Query: 319 SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGD---TNHIERLWSYLTTKELLSSW 375
             +   +    +V ++  +               E D    N+IERLW+YLT ++LL   
Sbjct: 522 HGATNDLTFTEEVDMKEMEKALQ-----------ERDYIFGNYIERLWAYLTIEQLLEKR 570

Query: 376 LQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMD--GLEEAHGMSAAMGPEP 433
             +  E EKE L  RA  L++ Y F+TP TSM +  P    D   + +  G  A   P  
Sbjct: 571 KNAHGE-EKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVS 629

Query: 434 VVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDIL 493
              S   +   P    + PY          VDGDPHF++  P     +CFNID  PG +L
Sbjct: 630 PAMSYLTSYQPP----QNPYY--------YVDGDPHFIIQIPEKDDALCFNIDEAPGTVL 677

Query: 494 RLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVIL-D 552
           RL+ D   +G+TVNG++ G        K ++TY   + I  N      +E+T  ++ L +
Sbjct: 678 RLIQD-AVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGI-ANAQMDFQVEVTTEKITLWN 735

Query: 553 GGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGF 612
                      +V V   GL + ++   N+ V+    + FV+++H   K  P  R  LGF
Sbjct: 736 RAVPSTFSWLDTVTVTQDGLSMMIN-RKNMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGF 794

Query: 613 YIANSEGLSSNCHGLLGQFLN------QDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLT 666
           Y+ +S  +S+  HGLLGQF         D R   DP                  P+A L 
Sbjct: 795 YVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPT----------------KPDATLV 838

Query: 667 VKGHQVPVVWKQRKIYNGEEQID----CWFARNNAAKLIDGEYKDYL 709
           VK HQ+ V    +K Y  +  I     CWF  NN   LIDG + DY+
Sbjct: 839 VKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYI 885


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score =  379 bits (973), Expect = e-105
 Identities = 237/701 (33%), Positives = 373/701 (53%), Gaps = 38/701 (5%)

Query: 22  NIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPL 78
           +++F+PTV QQ      + + + G F + YDV+R++ I D+ V N +F H+FAP++L  +
Sbjct: 231 HVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFAPQNLTNM 289

Query: 79  PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 138
            KNVVFV+D S SM G K++QTK+AL  IL D++P D F ++ F  R++ WK  L+  + 
Sbjct: 290 NKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASE 349

Query: 139 DSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVG 198
            +++  + ++   S    T++NG L R I +LN+            S+++ LTDG PT G
Sbjct: 350 ANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEG 409

Query: 199 ETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLI 258
            T   +IL N R A RG+  ++ +G G++VDF  LE +S+EN G  +R++E+ DA  QL 
Sbjct: 410 VTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQ 469

Query: 259 GFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTA 318
           GFY ++  PLL D+ + YP  +V+  T+     Y+ GSEI++AG++ D K      +V A
Sbjct: 470 GFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQA 529

Query: 319 -SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQ 377
               ++F I         +K  ++          G    NH+ERLW+YLT +ELL+  ++
Sbjct: 530 HGEGQEFSITCLVDEEEMKKLLRE---------RGHMLENHVERLWAYLTIQELLAKRMK 580

Query: 378 SDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQS 437
            D E E+  L  +A  +++ Y F+TP TSM +RG +   DGL+      +   P   +  
Sbjct: 581 VDRE-ERANLSSQALQMSLDYGFVTPLTSMSIRG-MADQDGLKPTIDKPSEDSPPLEMLG 638

Query: 438 VRG----AGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDIL 493
            R     +  QP P        R+    T VD DPHF++  P    T+CFNI+ +PG IL
Sbjct: 639 PRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVIL 698

Query: 494 RLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDG 553
            LV D  ++G +VNG+LIG  A   G +   TY   + I  N      LE+TP  + L+ 
Sbjct: 699 SLVQD-PNTGFSVNGQLIGNKARSPG-QHDGTYFGRLGI-ANPATDFQLEVTPQNITLNP 755

Query: 554 G-DRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGF 612
           G    V       V+   G+ V+++   N+ V++     F +++H   K +   +  LGF
Sbjct: 756 GFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGF 815

Query: 613 YIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQV 672
           Y+ +S  +S+  HGLLGQF +        P G   +  HP        P+A + V+  ++
Sbjct: 816 YVLDSHRMSARTHGLLGQFFH--------PIGFEVSDIHP--GSDPTKPDATMVVRNRRL 865

Query: 673 PVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDYL 709
            V    +K Y+ +     ++ CWF  NN A LIDG Y DY+
Sbjct: 866 TVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYI 906


>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
          Length = 1313

 Score =  308 bits (790), Expect = 9e-84
 Identities = 179/471 (38%), Positives = 264/471 (56%), Gaps = 23/471 (4%)

Query: 9   PPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVH 68
           PPST I + ET   I + PT+  Q+ I+ +GI+ DF+++YDV  E  IGD+Q+ + YF+H
Sbjct: 211 PPSTRIERGETCVRITYCPTLQDQSSISGSGIMADFLVQYDVVMEDIIGDVQIYDDYFIH 270

Query: 69  YFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV 128
           YFAP+ LPP+ KNVVFV+D S+SM GTK+ QTK A+  IL DL+  D F+II FS+ + V
Sbjct: 271 YFAPRGLPPMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNV 330

Query: 129 WK-DHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDR--SVS 185
           WK    I  T  ++   K Y+H M   G TD+N AL  A  +LN      G G     + 
Sbjct: 331 WKAGGSIQATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRIP 390

Query: 186 LIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTR 245
           LI+FLTDG+PT G T    IL+N R+A   +V +F++  G+D DF LL +LSLEN G+ R
Sbjct: 391 LIIFLTDGEPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIAR 450

Query: 246 RVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLV 305
           R++E+ DA  QL G Y+EI  PLL+D+R++Y    V  +   +FPNYF GSE+++AG++ 
Sbjct: 451 RIYEDTDAALQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQVQ 510

Query: 306 DRKLD-HLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 364
             K +  +H+       +  +   ++      +      G P P        + I RLW+
Sbjct: 511 PGKQELGIHLAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAP-----NVAHFIRRLWA 565

Query: 365 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 424
           Y+T  ELL +  Q+ D   +  L  +   L++ Y F+TP TS+ +    P+    E    
Sbjct: 566 YVTIGELLDAHFQARDTTTRHLLAAKVLNLSLEYNFVTPLTSLVM--VQPKQASEETRRQ 623

Query: 425 MSAAMGPE---PVVQSVRGAG---TQPGPLLK------KPYQPRIKISKTS 463
            S + GP+   P   S  G G    QP  + K      +P +P+  +S T+
Sbjct: 624 TSTSAGPDTIMPSSSSRHGLGVSTAQPALVPKVISPKSRPVKPKFYLSSTT 674



 Score =  156 bits (395), Expect = 6e-38
 Identities = 109/318 (34%), Positives = 159/318 (50%), Gaps = 39/318 (12%)

Query: 398  YRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRI 457
            Y FLTP          P  DG  E   +  A G      S+   G+  G  L K   P I
Sbjct: 1028 YTFLTPDEDGS-----PNWDGNSEEI-LGGAGG------SMESQGSSVG--LAKGTLPSI 1073

Query: 458  KISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPP 517
                +SVDGDPHFV+  P S   +CF ++G PGD+L+L+ D + +G+ V+G+L+GAP  P
Sbjct: 1074 FTFSSSVDGDPHFVIQIPHSEEKICFTLNGHPGDLLQLIEDPK-AGLHVSGKLLGAPPRP 1132

Query: 518  NGHKKQ-RTYLRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSV 576
             GHK Q RTY + IT+  +KP    + I+ S + L G   L L  +Q  ++    LE+ V
Sbjct: 1133 -GHKDQTRTYFQIITVTTDKPRAYTITISRSSISLRGEGTLRLSWDQPALLKRPQLELYV 1191

Query: 577  SANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDA 636
            +A A +T+ +   + F++L H Y+ P+  Q  HLGFY+AN  GLS +  GL+GQF + D 
Sbjct: 1192 AAAARLTLRLGPYLEFLVLRHRYRHPSTLQLPHLGFYVANGSGLSPSARGLIGQFQHADI 1251

Query: 637  RLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQI----DCWF 692
            RL   P GP     H                 G  VPV+  +R + +    +     CW 
Sbjct: 1252 RLVTGPMGPCLRRHH-----------------GPDVPVILGKRLLKDSPRLLPRWASCWL 1294

Query: 693  ARNNAAKLIDGE-YKDYL 709
             + +  +L+ G  Y  Y+
Sbjct: 1295 VKRSHVELLLGHPYLSYV 1312


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score =  304 bits (779), Expect = 2e-82
 Identities = 181/456 (39%), Positives = 264/456 (57%), Gaps = 21/456 (4%)

Query: 16  QNETFANIIFKPTVVQQARIA--QNGIL-GDFIIRYDVNREQSIGDIQVLNGYFVHYFAP 72
           QN+T A+I FKPT+ QQ +    Q  +L G+ IIRYDV+R  S G IQ+ NGYFVHYFAP
Sbjct: 206 QNKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAP 265

Query: 73  KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDH 132
           + L  +PKNVVFV+D S SM G K++QT++AL  IL DL P+D+F++I FS     W+  
Sbjct: 266 EGLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPS 325

Query: 133 LISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTD 192
           L+  + +++   + +   +   GGT+IN A+  A++LL+       + + SVSLI+ LTD
Sbjct: 326 LVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTD 385

Query: 193 GKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEED 252
           G PTVGET+   I NN REA  G+  +F +G G DV +  LEKL+L+N GL RR+HE+ D
Sbjct: 386 GDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSD 445

Query: 253 AGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHL 312
           +  QL  FY E+  PLL+ +  +YP ++V + T+  F   F GSE+++AGKL DR  D L
Sbjct: 446 SALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVL 505

Query: 313 HVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELL 372
              V+     + I  +T+  V  Q+A      SP+         N +ERLW+YLT ++LL
Sbjct: 506 TATVSGKLPTQNITFQTESSVAEQEAEFQ---SPK-----YIFHNFMERLWAYLTIQQLL 557

Query: 373 SSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPE 432
              + + D  +++ LR +A  L+++Y F+TP TSM +  P    D  E++      +  +
Sbjct: 558 EQTVSASD-ADQQALRNQALNLSLAYSFVTPLTSMVVTKP----DDQEQSQ-----VAEK 607

Query: 433 PVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDP 468
           P+    R      G    K Y    KI K      P
Sbjct: 608 PMEGESRNRNVHSGSTFFKYYLQGAKIPKPEASFSP 643


>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
           sapiens]
          Length = 1215

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 19/244 (7%)

Query: 83  VFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIR 142
           +F++D S+SM G  + + KDA+   L  L P   F+IIGF +  K       + + DS+ 
Sbjct: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422

Query: 143 DGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETH 201
                I  M +  GGT+I   L+  IR       H G       L+  +TDG       +
Sbjct: 423 MACDDIQRMKADMGGTNILSPLKWVIR----QPVHRG----HPRLLFVITDG----AVNN 470

Query: 202 TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFY 261
           T K+L   R  A    C ++ GIG +V  RL++ L+  + G    + E E    +++   
Sbjct: 471 TGKVLELVRNHAFSTRC-YSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529

Query: 262 DEIRTPLLSDIRID--YPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTAS 319
            +   P+LSD+ ++  +P ++ V  +     + F G  ++  G + D     LH+    S
Sbjct: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDAS---LHISNPRS 586

Query: 320 NSKK 323
           + ++
Sbjct: 587 DKRR 590


>gi|218505703 von Willebrand factor A domain containing 3A [Homo
            sapiens]
          Length = 1184

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 15/162 (9%)

Query: 78   LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--DRFSIIGFSNRIKVWKDHLIS 135
            L   V  +LD+S SM G  L+Q K  L  ++ +   +  D F+++ F+   + W+D L+ 
Sbjct: 956  LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVE 1014

Query: 136  VTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 195
             T  +  +   ++ H+   G T I  AL +A                 +  +  LTDGKP
Sbjct: 1015 TTDAACHEAMQWVTHLQAQGSTSILQALLKAFSF------------HDLEGLYLLTDGKP 1062

Query: 196  TVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLS 237
                +  L  +   RE    +V   ++   +      L KL+
Sbjct: 1063 DTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 17/219 (7%)

Query: 79  PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 138
           PK+VV ++D S SM G +L   K  + +IL  L   D F+II ++  +   +  L     
Sbjct: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313

Query: 139 DSIRDGK----VYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 194
            + R  K     ++  +   G   ++ AL  A  +L+ +  H+G G      I+ +TDG 
Sbjct: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDF-NHTGQGSICSQAIMLITDGA 372

Query: 195 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 253
               +T   K     R     +V IFT  IG +  F   L+ ++  N G   ++    D 
Sbjct: 373 VDTYDTIFAKYNWPDR-----KVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADV 427

Query: 254 GSQLIGFYDEIRTPLLSDIRID------YPPSSVVQATK 286
              ++ +   +  P + D   D      Y  S++ QA K
Sbjct: 428 QENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQK 466


>gi|110578649 cache domain containing 1 [Homo sapiens]
          Length = 1223

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 17/183 (9%)

Query: 77  PLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV------WK 130
           P  K++V +LD  AS+  T+L+  KDA   IL  +   D+ S++  ++ ++       +K
Sbjct: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYK 232

Query: 131 DHLISVTPDSIRDGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 189
             L   T ++ R    ++  + S    T      Q+A +L+     ++     +  +I++
Sbjct: 233 TFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIY 292

Query: 190 LTDGKPTVGETH-----TLKILNNTREAARGQVCIFTIGIGND-----VDFRLLEKLSLE 239
           L+ G  +   +      TL+++N         V I T  + ND      +   L  L+ +
Sbjct: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352

Query: 240 NCG 242
           N G
Sbjct: 353 NSG 355


>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
           [Homo sapiens]
          Length = 1137

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/196 (21%), Positives = 89/196 (45%), Gaps = 11/196 (5%)

Query: 79  PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRI----KVWKDHLI 134
           PK++V ++D S SM G ++   K  + TIL  L   D  +II +++ +      +K  L+
Sbjct: 289 PKDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILV 348

Query: 135 SVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 194
               D+    K+ +  +   G   ++ AL+ A ++L ++   +  G      I+ ++DG 
Sbjct: 349 QADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQF-QEAKQGSLCNQAIMLISDG- 406

Query: 195 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 253
             V +   +    N  +    +V +FT  IG +V F   ++ ++  N G   ++    D 
Sbjct: 407 -AVEDYEPVFEKYNWPDC---KVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADT 462

Query: 254 GSQLIGFYDEIRTPLL 269
              ++ +   +  P++
Sbjct: 463 QENVMEYLHVLSRPMV 478


>gi|118918435 von Willebrand factor A domain containing 3B [Homo
           sapiens]
          Length = 1294

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)

Query: 78  LPKNVVFVLDSSASMVGTKLRQTKDALFTILHD-LRPQDRFSIIGFSNRIKVWKDHLISV 136
           L  + +++L  ++  + +KL   KD +   + + L+ + +F+ + F  +   W++ L  V
Sbjct: 504 LHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEV 563

Query: 137 TPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 195
             D++   + +I  +     T+   AL+ A              D+    I  LTDG+P
Sbjct: 564 NEDNLEQAQSWIRDIKIGSSTNTLSALKTAF------------ADKETQAIYLLTDGRP 610


>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
           sapiens]
          Length = 1242

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 72/326 (22%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 72  PKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRI----- 126
           P  L    + ++F+LDSS+          KDA+   +  L PQ   ++  F   +     
Sbjct: 345 PGHLGTATRELLFLLDSSSVA-------HKDAIVLAVKSLPPQTLINLAVFGTLVQPLFP 397

Query: 127 --KVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 184
             +   D  + +  +SI   +V      P+G  D+  AL  A+        H     +  
Sbjct: 398 ESRPCSDDAVQLICESIETLQV------PSGPPDVLAALDWAVG----QPQHRAYPRQ-- 445

Query: 185 SLIVFLTDGKPTVGETH-TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGL 243
             +  LT   P    TH TL+++   R  AR     F+ G+G     +LL+ LS  + G 
Sbjct: 446 --LFLLTAASPMAATTHRTLELMRWHRGTAR----CFSFGLGPTCH-QLLQGLSALSRGQ 498

Query: 244 TRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQA--TKTLFPNYFNGSEIIIA 301
              +   +     L+    +   P LSDI +D+     V+A  T    P  + G +++  
Sbjct: 499 AYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGY 558

Query: 302 GKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIER 361
             L   ++D             +      V   P++A       P     G   T   E 
Sbjct: 559 CSLF--RVDGFRSRPPGGQEPGWQSSGGSVFPSPEEA-------PSAASPGTEPTGTSEP 609

Query: 362 LWSYLTTKELLSSWLQSDDEPEKERL 387
           L +   + EL S W   D E   + L
Sbjct: 610 LGTGTVSAELSSPWAARDSEQSTDAL 635


>gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]
          Length = 393

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 8/97 (8%)

Query: 360 ERLWSYLTTKELLSSWLQSDDEPEKERLRQRA--QALAVSYRFLT---PFTSMKLRGPVP 414
           ++ W Y    E LS    S+  P + RL +R   QALA+++   +   P T +  +GP  
Sbjct: 140 KKAWIYC---ESLSGPAPSEPTPGRGRLCRRGCVQALALAFALRSWRPPGTEVTSQGPRQ 196

Query: 415 RMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKK 451
                 +   + AA+GP+P   ++R     PG L  K
Sbjct: 197 PSSSGAKRRRLRAALGPQPTRSALRFPSASPGSLKAK 233


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 37/166 (22%), Positives = 77/166 (46%), Gaps = 19/166 (11%)

Query: 75  LPPLPKNVVFVLDSSASMVGTKLRQTKDALFTIL--HDLRPQD-RFSIIGFSNRIKV-WK 130
           LPP+P ++VF++D S S+  +  +Q KD L +++   ++ P   +  +  +S   +  W 
Sbjct: 173 LPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWD 232

Query: 131 DHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFL 190
            + +S     +      +  +   GG    G     +   N   A +G+   +  +++ +
Sbjct: 233 LNSLSTKEQVL----AAVRRLRYKGGNTFTGLALTHVLGQNLQPA-AGLRPEAAKVVILV 287

Query: 191 TDGKPTVGETHT-LKILNNTREAARGQVCIFTIGIGN--DVDFRLL 233
           TDGK +  + HT  ++L +        V +F +G+ N  + + RLL
Sbjct: 288 TDGK-SQDDVHTAARVLKDL------GVNVFAVGVKNADEAELRLL 326


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 33.1 bits (74), Expect = 0.96
 Identities = 35/157 (22%), Positives = 73/157 (46%), Gaps = 14/157 (8%)

Query: 73  KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDL-RPQDRFSIIGFSNRIK---V 128
           ++ P   +++VF++D S S+         + +  ++    RP  +FS++ FSN+ +    
Sbjct: 143 QECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPSTQFSLMQFSNKFQTHFT 202

Query: 129 WKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIV 188
           +++   S  P S+      +H +   G T    A+Q  +  L  + A  G    +  +++
Sbjct: 203 FEEFRRSSNPLSL---LASVHQLQ--GFTYTATAIQNVVHRL--FHASYGARRDAAKILI 255

Query: 189 FLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIG 225
            +TDGK   G++   K +    +AA   +  + IG+G
Sbjct: 256 VITDGKKE-GDSLDYKDVIPMADAA--GIIRYAIGVG 289


>gi|239749207 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 369

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 423 HGMSAAMGPEPVVQSVRGAGTQPGPLLKKP-YQPRIKISKTSVDGDPHFVVDFP---LSR 478
           H   A    E  V    G G QP P L++P  Q  + +S   + G+P      P    S 
Sbjct: 40  HTGGAEQFGEEAVPEGAGLGAQPPPHLQRPQVQTNVLLSPRRLSGEPQRTRPLPPTTFSN 99

Query: 479 LTVCFNIDGQPGDILRLVS 497
           + V   + G P D L LV+
Sbjct: 100 VRVSRGVQGDPKDELDLVA 118


>gi|239508971 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 369

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 423 HGMSAAMGPEPVVQSVRGAGTQPGPLLKKP-YQPRIKISKTSVDGDPHFVVDFP---LSR 478
           H   A    E  V    G G QP P L++P  Q  + +S   + G+P      P    S 
Sbjct: 40  HTGGAEQFGEEAVPEGAGLGAQPPPHLQRPQVQTNVLLSPRRLSGEPQRTRPLPPTTFSN 99

Query: 479 LTVCFNIDGQPGDILRLVS 497
           + V   + G P D L LV+
Sbjct: 100 VRVSRGVQGDPKDELDLVA 118


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 10/135 (7%)

Query: 78  LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--------DRFSIIGFSNRIKVW 129
           LP+   F+LD    +      Q ++ + + L D   +        D F    FS    VW
Sbjct: 251 LPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVW 310

Query: 130 KDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 189
              L +V PD++ +   + + +S +  T + G    +   L  Y     +G R + L  +
Sbjct: 311 NSQLDAVCPDTMNNPLSH-YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW 369

Query: 190 -LTDGKPTVGETHTL 203
              DG P +   HTL
Sbjct: 370 DGPDGMPVIYHGHTL 384


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 10/135 (7%)

Query: 78  LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--------DRFSIIGFSNRIKVW 129
           LP+   F+LD    +      Q ++ + + L D   +        D F    FS    VW
Sbjct: 251 LPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVW 310

Query: 130 KDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 189
              L +V PD++ +   + + +S +  T + G    +   L  Y     +G R + L  +
Sbjct: 311 NSQLDAVCPDTMNNPLSH-YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW 369

Query: 190 -LTDGKPTVGETHTL 203
              DG P +   HTL
Sbjct: 370 DGPDGMPVIYHGHTL 384


>gi|4826988 ribosomal protein L3-like [Homo sapiens]
          Length = 407

 Score = 30.4 bits (67), Expect = 6.2
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 3/81 (3%)

Query: 142 RDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGET- 200
           R  K +I  +   GGT          RL  +   HS      V  ++ +T G+   G T 
Sbjct: 174 RQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTS 233

Query: 201 --HTLKILNNTREAARGQVCI 219
             HT K+   T +  R   CI
Sbjct: 234 RWHTKKLPRKTHKGLRKVACI 254


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 30.0 bits (66), Expect = 8.1
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)

Query: 421 EAHGMSAAMGPEPVVQSVRGAGTQPGPLL--KKPYQPRIKISKTSVDGDPHF 470
           EA G +AA  P   +++ + +G +PGP     KP  P  K  K +V G  H+
Sbjct: 4   EASGPAAAAAPS--LEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHY 53


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,486,447
Number of Sequences: 37866
Number of extensions: 1458616
Number of successful extensions: 3358
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3313
Number of HSP's gapped (non-prelim): 26
length of query: 742
length of database: 18,247,518
effective HSP length: 110
effective length of query: 632
effective length of database: 14,082,258
effective search space: 8899987056
effective search space used: 8899987056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.