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Search of human proteins with 153792329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792329 microfibrillar-associated protein 3-like isoform 1
[Homo sapiens]
(409 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792329 microfibrillar-associated protein 3-like isoform 1 ... 811 0.0
gi|57222338 microfibrillar-associated protein 3-like isoform 2 [... 605 e-173
gi|5174555 microfibrillar-associated protein 3 isoform 1 [Homo s... 303 2e-82
gi|205277369 microfibrillar-associated protein 3 isoform 2 [Homo... 239 3e-63
gi|222144233 fibroblast growth factor receptor 2 isoform 4 precu... 56 5e-08
gi|154275767 ADAMTS-like 1 isoform 4 precursor [Homo sapiens] 56 7e-08
gi|153792294 myopalladin [Homo sapiens] 55 9e-08
gi|31542244 leucine rich repeat and fibronectin type III domain ... 55 1e-07
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 55 1e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 53 4e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 53 4e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 53 4e-07
gi|224994173 roundabout 1 isoform d [Homo sapiens] 53 6e-07
gi|224994171 roundabout 1 isoform c [Homo sapiens] 53 6e-07
gi|19743806 roundabout 1 isoform b [Homo sapiens] 53 6e-07
gi|110349717 titin isoform novex-2 [Homo sapiens] 53 6e-07
gi|110349713 titin isoform novex-1 [Homo sapiens] 53 6e-07
gi|110349715 titin isoform N2-B [Homo sapiens] 53 6e-07
gi|119220552 sidekick 1 [Homo sapiens] 53 6e-07
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 53 6e-07
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 53 6e-07
gi|4506569 roundabout 1 isoform a [Homo sapiens] 53 6e-07
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 52 1e-06
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 52 1e-06
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 52 1e-06
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 52 1e-06
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 52 1e-06
gi|55956790 neurotrophic tyrosine kinase, receptor, type 2 isofo... 52 1e-06
gi|65506779 neurotrophic tyrosine kinase, receptor, type 2 isofo... 52 1e-06
gi|65506769 neurotrophic tyrosine kinase, receptor, type 2 isofo... 52 1e-06
>gi|153792329 microfibrillar-associated protein 3-like isoform 1
[Homo sapiens]
Length = 409
Score = 811 bits (2095), Expect = 0.0
Identities = 409/409 (100%), Positives = 409/409 (100%)
Query: 1 MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKE 60
MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKE
Sbjct: 1 MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKE 60
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR
Sbjct: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
Query: 121 GKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLK 180
GKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLK
Sbjct: 121 GKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLK 180
Query: 181 KTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARS 240
KTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARS
Sbjct: 181 KTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARS 240
Query: 241 VPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSLKRSDSPA 300
VPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSLKRSDSPA
Sbjct: 241 VPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSLKRSDSPA 300
Query: 301 ADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPS 360
ADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPS
Sbjct: 301 ADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPS 360
Query: 361 TDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV 409
TDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV
Sbjct: 361 TDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV 409
>gi|57222338 microfibrillar-associated protein 3-like isoform 2
[Homo sapiens]
Length = 306
Score = 605 bits (1561), Expect = e-173
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTI 163
MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTI
Sbjct: 1 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTI 60
Query: 164 VMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVT 223
VMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVT
Sbjct: 61 VMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVT 120
Query: 224 QFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADR 283
QFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADR
Sbjct: 121 QFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADR 180
Query: 284 DEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDV 343
DEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDV
Sbjct: 181 DEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDV 240
Query: 344 EETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCI 403
EETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCI
Sbjct: 241 EETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCI 300
Query: 404 IYESHV 409
IYESHV
Sbjct: 301 IYESHV 306
>gi|5174555 microfibrillar-associated protein 3 isoform 1 [Homo
sapiens]
Length = 362
Score = 303 bits (776), Expect = 2e-82
Identities = 167/283 (59%), Positives = 202/283 (71%), Gaps = 8/283 (2%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D II KEG S I C + W+NS G+ L D + RGG KW + D+ LNIT
Sbjct: 59 DVIIAKEGTSVSIECLLTASHYEDVHWHNSKGQQL----DGRSRGG-KWLVSDN-FLNIT 112
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLC 173
V+F DRG YTC ++ + +VTLRVIFTSGDM VYYM+VCL+AFTI ++LN+TRLC
Sbjct: 113 NVAFDDRGLYTCFVTSPI-RASYSVTLRVIFTSGDMSVYYMIVCLIAFTITLILNVTRLC 171
Query: 174 MMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARY 233
MMSSHL+KTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARY
Sbjct: 172 MMSSHLRKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARY 231
Query: 234 IEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSL 293
IEELARSVPLPPLI+NCR +EE+ E V +++ + E + +Y I +
Sbjct: 232 IEELARSVPLPPLILNCRAFVEEMFEAVRVDDP-DDLGERIKERPALNAQGGIYVINPEM 290
Query: 294 KRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGG 336
RS+SP DSD SL+EQ Q+IA++VSVH QS+ + D + G
Sbjct: 291 GRSNSPGGDSDDGSLNEQGQEIAVQVSVHLQSETKSIDTESQG 333
>gi|205277369 microfibrillar-associated protein 3 isoform 2 [Homo
sapiens]
Length = 216
Score = 239 bits (610), Expect = 3e-63
Identities = 123/188 (65%), Positives = 147/188 (78%), Gaps = 1/188 (0%)
Query: 149 MGVYYMVVCLVAFTIVMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRI 208
M VYYM+VCL+AFTI ++LN+TRLCMMSSHL+KTEKAINEFFRTEGAEKLQKAFEIAKRI
Sbjct: 1 MSVYYMIVCLIAFTITLILNVTRLCMMSSHLRKTEKAINEFFRTEGAEKLQKAFEIAKRI 60
Query: 209 PIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQ 268
PIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLI+NCR +EE+ E V +++
Sbjct: 61 PIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLILNCRAFVEEMFEAVRVDDP-D 119
Query: 269 NFVRHTPEGQEAADRDEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKE 328
+ E + +Y I + RS+SP DSD SL+EQ Q+IA++VSVH QS+ +
Sbjct: 120 DLGERIKERPALNAQGGIYVINPEMGRSNSPGGDSDDGSLNEQGQEIAVQVSVHLQSETK 179
Query: 329 HADDQEGG 336
D + G
Sbjct: 180 SIDTESQG 187
>gi|222144233 fibroblast growth factor receptor 2 isoform 4
precursor [Homo sapiens]
Length = 709
Score = 56.2 bits (134), Expect = 5e-08
Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
V N+ C G P P +W + GK K+E R GG + L + V
Sbjct: 169 VPAANTVKFRCPAGGNPMPTMRWLKN-GKEFKQEH----RIGGYKVRNQHWSLIMESVVP 223
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRVI-------FTSGDMGVYYMVVCLVAFTIVMVLNIT 170
SD+G YTCV N YG++N+T L V+ T+ + + C+ F I ++
Sbjct: 224 SDKGNYTCVVENEYGSINHTYHLDVVAPGREKEITASPDYLEIAIYCIGVFLIACMVVTV 283
Query: 171 RLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPI 210
LC M + KK +F KL K + +++ +
Sbjct: 284 ILCRMKNTTKKP-----DFSSQPAVHKLTKRIPLRRQVTV 318
>gi|154275767 ADAMTS-like 1 isoform 4 precursor [Homo sapiens]
Length = 1762
Score = 55.8 bits (133), Expect = 7e-08
Identities = 37/120 (30%), Positives = 58/120 (48%), Gaps = 14/120 (11%)
Query: 24 TLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNS 83
TLA V S + N +V V I T I +G + INC V G+P+ + W+ +
Sbjct: 1266 TLAGKPLVKTSRMTVINTEKPAVTVDIGST--IKTVQGVNVTINCQVAGVPEAEVTWFRN 1323
Query: 84 IGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
KL G +H+ LL +T VS SD+G Y+C A+N++G + + L ++
Sbjct: 1324 KSKL-----------GSPHHLHEGSLL-LTNVSSSDQGLYSCRAANLHGELTESTQLLIL 1371
Score = 35.4 bits (80), Expect = 0.094
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
+++ GNSAL+ C + G P P W++ ++ G + +L + +
Sbjct: 1406 LVLDPGNSALLGCPIKGHPVPNITWFHGGQPIV------TATGLTHHILAAGQILQVANL 1459
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTL 140
S +G+++C+A N G + +L
Sbjct: 1460 SGGSQGEFSCLAQNEAGVLMQKASL 1484
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 55.5 bits (132), Expect = 9e-08
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 8/126 (6%)
Query: 22 VSTLATAKSVTN--STLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFK 79
V+T+ +S TN L+G ++ + PV ++ EG + C V G P P+ +
Sbjct: 410 VATIQQCQSPTNYLQGLDGKPII--AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVE 467
Query: 80 WYNSIGKLLKEEEDEK---ERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNN 136
WY G L+++ D + ++ + + L I +V D G +TC ASN YGTV++
Sbjct: 468 WYRE-GTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSS 526
Query: 137 TVTLRV 142
L V
Sbjct: 527 IAQLHV 532
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
LG P + V EG ++C V GIP PQ +WY GK L+ D G
Sbjct: 265 LGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCE-GKELENSPDIHIVQAG-- 321
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+H L I + D G+Y+C ASNIYGT + + + +
Sbjct: 322 NLHS---LTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKER--GGGKWQM 104
P+ R H V EG+ C + GIP P+ W+ ++ K E K R G G +
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVN 135
H I + D G YT +A+N G ++
Sbjct: 1005 H------IESTTSDDDGNYTIMAANPQGRIS 1029
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 25 LATAKSVTNSTLNGTNVVLGSV---PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
+AT K+ NS +VV V PVI+ + + V EG+ + C V G+P P F W
Sbjct: 1147 IATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYW- 1205
Query: 82 NSIGKLLKEEEDEKERGGGKWQMHDS----GLLNITKVSFSDRGKYTCVASNIYGTVNNT 137
K++ + + MH L I SD G YT A N G V+ T
Sbjct: 1206 -------KKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 138 VTLRV 142
L +
Sbjct: 1259 ARLDI 1263
Score = 35.4 bits (80), Expect = 0.094
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + ++ EG ++C V G+P P+ W + +L + K + +
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPD-------ASHKMLVRE 1125
Query: 107 SGL--LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+G+ L I ++ D G Y C+A+N G + ++ L V+
Sbjct: 1126 TGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1164
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P+I T + V EG A + C G P+P W + GKL+ + ++D
Sbjct: 287 PLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLIS--------NATRSLVYD 338
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+G L+I + D G +TC+ASN G V L +I
Sbjct: 339 NGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHII 375
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 54.7 bits (130), Expect = 1e-07
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
V G S LI C G+P P F+WY KL ++ G +L +T V+
Sbjct: 235 VTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQ-----GIIIQNFSTRSILTVTNVTQ 289
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRV-------IFTSGDM--GVYYMVVCLVAFTIVMVL 167
G YTCVA+N GT N ++ L I S D+ +Y+V+ L +FT + L
Sbjct: 290 EHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYL 348
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 53.1 bits (126), Expect = 4e-07
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D ++V+ G+ A+++C +P+P WY L+ + + RGG + L I
Sbjct: 1849 DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR--------LEIQ 1900
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD+G Y+C SN+ G T TL V
Sbjct: 1901 EAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1929
Score = 52.4 bits (124), Expect = 7e-07
Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 12/121 (9%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L AK+ S + T +V+ PVI + EG+ A + C G P+P W
Sbjct: 2825 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITW---- 2880
Query: 85 GKLLKEEEDEKERGG--GKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
++D + G GK+ + SG L + + D G YTC A N G V L +
Sbjct: 2881 ------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934
Query: 143 I 143
+
Sbjct: 2935 L 2935
Score = 45.8 bits (107), Expect = 7e-05
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
TA++ ST V + +VP I + + V +AL+ C G+P P W
Sbjct: 2462 TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW------ 2515
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+++ + ++++ G L I V D G Y C+ASN G+ LRV+
Sbjct: 2516 --RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 2570
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 13/107 (12%)
Query: 40 NVVLGSVPVIIARTDHII-VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
N+ + PV R H + V+EG+ ++C G+P P+ W ++ + G
Sbjct: 964 NLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISW---------RKDGQPLPG 1014
Query: 99 GGKWQMHDSG---LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G H S LL + + + G YTC SN+ G + + L V
Sbjct: 1015 EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEV 1061
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I V +G +A + C+V G P P+ W+ G+ L RG D LL + +
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKD-GRPLA-------RGDAHHISPDGVLLQVLQA 1315
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ S G Y+C+A+N G L V+ +G
Sbjct: 1316 NLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 1350
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 41 VVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGG 100
+VL S PV + V+ G+ + C G P P +W + + R
Sbjct: 3112 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL---------QAGQPLRASR 3162
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGT 133
+ + G L + V D G Y CVA N+ G+
Sbjct: 3163 RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGS 3195
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T + V E + + C G+P P W+ L + RGG + L +
Sbjct: 318 TGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQ--------LQL 369
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD G YTC ASN G L V
Sbjct: 370 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 399
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 8/85 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
V E S + C G+P P W+ G D +L I +
Sbjct: 706 VLENASVTLECLASGVPPPDVSWFKG--------HQPVSSWMGVTVSVDGRVLRIEQAQL 757
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y CVASN+ G+ LRV
Sbjct: 758 SDAGSYRCVASNVAGSTELRYGLRV 782
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 13/90 (14%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
LG V V +T K ++ + C + +P P +WY G+ + + G G+
Sbjct: 1450 LGEVGVKEVKT-----KVNSTLTLECESWAVPPPTIRWYKD-GQPVTPSSRLQVLGEGR- 1502
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
LL I SD G+Y CVA+N+ G
Sbjct: 1503 ------LLQIQPTQVSDSGRYLCVATNVAG 1526
Score = 38.5 bits (88), Expect = 0.011
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T++ + E N A + C IP P WY L +E +GG +L I
Sbjct: 1566 TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGG--------RVLQI 1617
Query: 113 TKVSFSDRGKYTCVASNIYG 132
V + G+Y+C ASN G
Sbjct: 1618 PLVRAENAGRYSCKASNEVG 1637
Score = 37.7 bits (86), Expect = 0.019
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 68 CSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVA 127
C GIP P +W+ E+ G + + +L +T+ D G Y+C+A
Sbjct: 1183 CEAMGIPPPAIRWFRG--------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1234
Query: 128 SNIYGTVNNTVTLRVI 143
SN G ++ V+
Sbjct: 1235 SNEAGEARRNFSVEVL 1250
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 10/95 (10%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSG 108
+AR H++ EG ++C G P P W LK+ + G + + D G
Sbjct: 2032 VAREHHVL--EGQEVRLDCEADGQPPPDVAW-------LKDGSPLGQDMGPHLRFYLDGG 2082
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L + + SD G YTCVA N G T+ V+
Sbjct: 2083 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 2117
Score = 36.2 bits (82), Expect = 0.055
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 8/82 (9%)
Query: 62 NSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRG 121
+S + C V+ P+P+ WY L EE + + + L + + SD G
Sbjct: 1762 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEE--------VFLLPGTHTLQLGRARLSDSG 1813
Query: 122 KYTCVASNIYGTVNNTVTLRVI 143
YTC A N G V L V+
Sbjct: 1814 MYTCEALNAAGRDQKLVQLSVL 1835
Score = 35.8 bits (81), Expect = 0.072
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 9/83 (10%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSD 119
G + C G+P PQ +W +L GG Q+ + G +L IT D
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLP--------GGPHLQVQEDGQVLRITGSHVGD 283
Query: 120 RGKYTCVASNIYGTVNNTVTLRV 142
G+Y CVA + G LRV
Sbjct: 284 EGRYQCVAFSPAGQQARDFQLRV 306
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 12/100 (12%)
Query: 47 PVIIARTDHII----VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
PVI+ T+ ++ V ++ + C G P P W + +
Sbjct: 1651 PVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV------- 1703
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D +L ++ +D Y CVA N G+ TLRV
Sbjct: 1704 -LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 1742
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 9/78 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
L+ C GIP P W ++E G Q+ G L I S D G Y
Sbjct: 2775 LLPCEASGIPRPTITW---------QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYL 2825
Query: 125 CVASNIYGTVNNTVTLRV 142
C+A N G+ L V
Sbjct: 2826 CIAKNSAGSAMGKTRLVV 2843
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 9/86 (10%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+++ G S ++C V G P P W L RG +G L I +
Sbjct: 3036 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL---------RGSHLRHQLQNGSLTIHR 3086
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTL 140
D G+Y C+A N G V L
Sbjct: 3087 TERDDAGRYQCLAENEMGVAKKVVIL 3112
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 66 INCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSDRGKYT 124
+ C+ G P P W LK+ G Q+ G +L + SD G+Y+
Sbjct: 806 LTCNATGAPSPTLMW-------LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 858
Query: 125 CVASNIYGTVNNTVTLRV 142
CVA + G V L+V
Sbjct: 859 CVAVSAVGEDRQDVVLQV 876
Score = 34.3 bits (77), Expect = 0.21
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 8/96 (8%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ ++ V S + C + +P P W+ G+ L+ G D
Sbjct: 880 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKD-GRPLEPRP-------GVHLSAD 931
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
LL + + D G YTC A N G L V
Sbjct: 932 KALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITK 114
++ + G + C V G P W L + + +H SG L I+K
Sbjct: 2132 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQ---------RTLLHGSGHTLRISK 2182
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRV 142
V +D G +TCVA++ G + TL+V
Sbjct: 2183 VQLADAGIFTCVAASPAGVADRNFTLQV 2210
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ C GIP P W + +L RG G +++ SG L I + G+YT
Sbjct: 2684 VLTCHSTGIPAPTVSWSKAGAQL-------GARGSG-YRVSPSGALEIGQALPIHAGRYT 2735
Query: 125 CVASNIYGTVNNTVTLRV 142
C A N G + V L V
Sbjct: 2736 CSARNSAGVAHKHVFLTV 2753
Score = 33.5 bits (75), Expect = 0.36
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 7/75 (9%)
Query: 68 CSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVA 127
C +G P PQ W K E G + + G L + VS +D G Y C A
Sbjct: 24 CGTHGTPKPQVTWR-------KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQA 76
Query: 128 SNIYGTVNNTVTLRV 142
+N G+ + L V
Sbjct: 77 TNEVGSTSRRAKLVV 91
Score = 33.5 bits (75), Expect = 0.36
Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 8/126 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L A + S G ++ + P I ++ + AL+ C G P P W+
Sbjct: 2551 LCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2610
Query: 85 GKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNN--TVTLRV 142
KL + G +++ S L +T D ++ CV SN G + VT+ V
Sbjct: 2611 QKL------DFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 2664
Query: 143 IFTSGD 148
T D
Sbjct: 2665 PPTIAD 2670
Score = 33.1 bits (74), Expect = 0.47
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I KV D G YTC A+N+ G V L+V+
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 692
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 8/92 (8%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLN 111
+T+ + G+ ++ C V G+P P W ++ E + G L
Sbjct: 1939 KTETVSQVAGSPLVLTCDVSGVPAPTVTWL--------KDRMPVESSAVHGVVSRGGRLQ 1990
Query: 112 ITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
++++ + G YTCVA N + V+
Sbjct: 1991 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVL 2022
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ CSV P P+ W+ G +L+E+ + G++ L + +S +D G Y+
Sbjct: 2409 VLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERGRF-------LQLQALSTADSGDYS 2460
Query: 125 CVASNIYGTVN 135
C A N G+ +
Sbjct: 2461 CTARNAAGSTS 2471
Score = 31.6 bits (70), Expect = 1.4
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 13/89 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQMHDSGLLNITK 114
+V++G A + C+ G P P W E D + G G + L++ +
Sbjct: 1079 VVQDG-VATLECNATGKPPPTVTW----------ERDGQPVGAELGLQLQNQGQSLHVER 1127
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+ G+Y+CVA N+ G L V+
Sbjct: 1128 AQAAHTGRYSCVAENLAGRAERKFELSVL 1156
Score = 29.6 bits (65), Expect = 5.2
Identities = 20/88 (22%), Positives = 31/88 (35%), Gaps = 12/88 (13%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
++V G+ + C G+P P W LL + + L + V
Sbjct: 2225 VVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS------------LEQGPSLQLEAV 2272
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVI 143
D G Y+CVA + G L V+
Sbjct: 2273 GAGDSGTYSCVAVSEAGEARRHFQLTVM 2300
Score = 28.9 bits (63), Expect = 8.8
Identities = 17/72 (23%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
G + C G P P W++ + + E E D +L + +
Sbjct: 420 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLET--------DGSVLRLESPGEASS 471
Query: 121 GKYTCVASNIYG 132
G Y+CVAS+ G
Sbjct: 472 GLYSCVASSPAG 483
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 53.1 bits (126), Expect = 4e-07
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D ++V+ G+ A+++C +P+P WY L+ + + RGG + L I
Sbjct: 3040 DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR--------LEIQ 3091
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD+G Y+C SN+ G T TL V
Sbjct: 3092 EAQVSDKGLYSCKVSNVAGEAVRTFTLTV 3120
Score = 52.4 bits (124), Expect = 7e-07
Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 12/121 (9%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L AK+ S + T +V+ PVI + EG+ A + C G P+P W
Sbjct: 4016 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITW---- 4071
Query: 85 GKLLKEEEDEKERGG--GKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
++D + G GK+ + SG L + + D G YTC A N G V L +
Sbjct: 4072 ------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Query: 143 I 143
+
Sbjct: 4126 L 4126
Score = 45.8 bits (107), Expect = 7e-05
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
TA++ ST V + +VP I + + V +AL+ C G+P P W
Sbjct: 3653 TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW------ 3706
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+++ + ++++ G L I V D G Y C+ASN G+ LRV+
Sbjct: 3707 --RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 3761
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 41 VVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGG 100
+ +G P + + V+ G SAL+ C G P P W G+ L G
Sbjct: 780 LAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGR--GS 837
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ + DSG+L V+ D+ Y C A N++G V L V
Sbjct: 838 RSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 13/107 (12%)
Query: 40 NVVLGSVPVIIARTDHII-VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
N+ + PV R H + V+EG+ ++C G+P P+ W ++ + G
Sbjct: 2155 NLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISW---------RKDGQPLPG 2205
Query: 99 GGKWQMHDSG---LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G H S LL + + + G YTC SN+ G + + L V
Sbjct: 2206 EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEV 2252
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/115 (26%), Positives = 41/115 (35%), Gaps = 8/115 (6%)
Query: 28 AKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKL 87
A + S +V+ P I H I EG A + C G+P P W L
Sbjct: 957 ATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL 1016
Query: 88 LKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G + + G L I + S D G Y C A+N G + + L V
Sbjct: 1017 TSR--------GPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I V +G +A + C+V G P P+ W+ G+ L RG D LL + +
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKD-GRPLA-------RGDAHHISPDGVLLQVLQA 2506
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ S G Y+C+A+N G L V+ +G
Sbjct: 2507 NLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 2541
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 41 VVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGG 100
+++ P + T +G ++CS G P P W E + +
Sbjct: 602 LLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW---------SRESQALQEDS 652
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
+ + G L I V+ D G Y+C A+N GT TVTL
Sbjct: 653 RIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 692
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 41 VVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGG 100
+VL S PV + V+ G+ + C G P P +W + + R
Sbjct: 4303 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL---------QAGQPLRASR 4353
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGT 133
+ + G L + V D G Y CVA N+ G+
Sbjct: 4354 RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGS 4386
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T + V E + + C G+P P W+ L + RGG + L +
Sbjct: 1509 TGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQ--------LQL 1560
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD G YTC ASN G L V
Sbjct: 1561 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 8/85 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
V E S + C G+P P W+ G D +L I +
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFKG--------HQPVSSWMGVTVSVDGRVLRIEQAQL 1948
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y CVASN+ G+ LRV
Sbjct: 1949 SDAGSYRCVASNVAGSTELRYGLRV 1973
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 11/96 (11%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + A ++V G A++ C G+P P+ WY +++ E
Sbjct: 698 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-----------S 746
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
SG L I D G YTC A N G + + L V
Sbjct: 747 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 13/90 (14%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
LG V V +T K ++ + C + +P P +WY G+ + + G G+
Sbjct: 2641 LGEVGVKEVKT-----KVNSTLTLECESWAVPPPTIRWYKD-GQPVTPSSRLQVLGEGR- 2693
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
LL I SD G+Y CVA+N+ G
Sbjct: 2694 ------LLQIQPTQVSDSGRYLCVATNVAG 2717
Score = 38.5 bits (88), Expect = 0.011
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T++ + E N A + C IP P WY L +E +GG +L I
Sbjct: 2757 TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGG--------RVLQI 2808
Query: 113 TKVSFSDRGKYTCVASNIYG 132
V + G+Y+C ASN G
Sbjct: 2809 PLVRAENAGRYSCKASNEVG 2828
Score = 37.7 bits (86), Expect = 0.019
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 68 CSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVA 127
C GIP P +W+ E+ G + + +L +T+ D G Y+C+A
Sbjct: 2374 CEAMGIPPPAIRWFRG--------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 2425
Query: 128 SNIYGTVNNTVTLRVI 143
SN G ++ V+
Sbjct: 2426 SNEAGEARRNFSVEVL 2441
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 10/95 (10%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSG 108
+AR H++ EG ++C G P P W LK+ + G + + D G
Sbjct: 3223 VAREHHVL--EGQEVRLDCEADGQPPPDVAW-------LKDGSPLGQDMGPHLRFYLDGG 3273
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L + + SD G YTCVA N G T+ V+
Sbjct: 3274 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 3308
Score = 36.2 bits (82), Expect = 0.055
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 8/82 (9%)
Query: 62 NSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRG 121
+S + C V+ P+P+ WY L EE + + + L + + SD G
Sbjct: 2953 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEE--------VFLLPGTHTLQLGRARLSDSG 3004
Query: 122 KYTCVASNIYGTVNNTVTLRVI 143
YTC A N G V L V+
Sbjct: 3005 MYTCEALNAAGRDQKLVQLSVL 3026
Score = 35.8 bits (81), Expect = 0.072
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 9/83 (10%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSD 119
G + C G+P PQ +W +L GG Q+ + G +L IT D
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLP--------GGPHLQVQEDGQVLRITGSHVGD 1474
Query: 120 RGKYTCVASNIYGTVNNTVTLRV 142
G+Y CVA + G LRV
Sbjct: 1475 EGRYQCVAFSPAGQQARDFQLRV 1497
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
G + +NC G P+PQ W G +L+ G G G ++ + SD
Sbjct: 1134 GEALDLNCVAEGNPEPQLSWSKD-GVVLQ--------GRGP-----QGSVHFAAIRTSDA 1179
Query: 121 GKYTCVASNIYGTVNNTVTLRVI 143
G+Y C ASN G V LRV+
Sbjct: 1180 GRYRCEASNSAGVDAWEVELRVL 1202
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
G +A + C G P PQ W K E G + + G L + VS +D
Sbjct: 1221 GENASLPCPARGTPKPQVTWR-------KGPSSEPLHGQPGVAVLEEGSLFLASVSPADS 1273
Query: 121 GKYTCVASNIYGTVNNTVTLRV 142
G Y C A+N G+ + L V
Sbjct: 1274 GDYECQATNEVGSTSRRAKLVV 1295
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 12/100 (12%)
Query: 47 PVIIARTDHII----VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
PVI+ T+ ++ V ++ + C G P P W + +
Sbjct: 2842 PVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV------- 2894
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D +L ++ +D Y CVA N G+ TLRV
Sbjct: 2895 -LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 2933
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 9/78 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
L+ C GIP P W ++E G Q+ G L I S D G Y
Sbjct: 3966 LLPCEASGIPRPTITW---------QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYL 4016
Query: 125 CVASNIYGTVNNTVTLRV 142
C+A N G+ L V
Sbjct: 4017 CIAKNSAGSAMGKTRLVV 4034
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 9/86 (10%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+++ G S ++C V G P P W L RG +G L I +
Sbjct: 4227 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL---------RGSHLRHQLQNGSLTIHR 4277
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTL 140
D G+Y C+A N G V L
Sbjct: 4278 TERDDAGRYQCLAENEMGVAKKVVIL 4303
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 66 INCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSDRGKYT 124
+ C+ G P P W LK+ G Q+ G +L + SD G+Y+
Sbjct: 1997 LTCNATGAPSPTLMW-------LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 2049
Query: 125 CVASNIYGTVNNTVTLRV 142
CVA + G V L+V
Sbjct: 2050 CVAVSAVGEDRQDVVLQV 2067
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 8/96 (8%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ ++ V S + C + +P P W+ G+ L+ G D
Sbjct: 2071 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKD-GRPLEPRP-------GVHLSAD 2122
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
LL + + D G YTC A N G L V
Sbjct: 2123 KALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 2158
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITK 114
++ + G + C V G P W L + + +H SG L I+K
Sbjct: 3323 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQ---------RTLLHGSGHTLRISK 3373
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRV 142
V +D G +TCVA++ G + TL+V
Sbjct: 3374 VQLADAGIFTCVAASPAGVADRNFTLQV 3401
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ C GIP P W + +L RG G +++ SG L I + G+YT
Sbjct: 3875 VLTCHSTGIPAPTVSWSKAGAQL-------GARGSG-YRVSPSGALEIGQALPIHAGRYT 3926
Query: 125 CVASNIYGTVNNTVTLRV 142
C A N G + V L V
Sbjct: 3927 CSARNSAGVAHKHVFLTV 3944
Score = 33.5 bits (75), Expect = 0.36
Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 8/116 (6%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
TA S + +V+ P + ++ V G +A+++C V G W
Sbjct: 497 TAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRV 556
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L G Q+ D L I+ + +D G+Y CVASN G +V L V
Sbjct: 557 LPAST-------GRVAQLADLSL-EISGIIPTDGGRYQCVASNANGVTRASVWLLV 604
Score = 33.5 bits (75), Expect = 0.36
Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 8/126 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L A + S G ++ + P I ++ + AL+ C G P P W+
Sbjct: 3742 LCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 3801
Query: 85 GKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNN--TVTLRV 142
KL + G +++ S L +T D ++ CV SN G + VT+ V
Sbjct: 3802 QKL------DFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 3855
Query: 143 IFTSGD 148
T D
Sbjct: 3856 PPTIAD 3861
Score = 33.1 bits (74), Expect = 0.47
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I KV D G YTC A+N+ G V L+V+
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 1883
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 8/92 (8%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLN 111
+T+ + G+ ++ C V G+P P W ++ E + G L
Sbjct: 3130 KTETVSQVAGSPLVLTCDVSGVPAPTVTWL--------KDRMPVESSAVHGVVSRGGRLQ 3181
Query: 112 ITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
++++ + G YTCVA N + V+
Sbjct: 3182 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVL 3213
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ CSV P P+ W+ G +L+E+ + G++ L + +S +D G Y+
Sbjct: 3600 VLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERGRF-------LQLQALSTADSGDYS 3651
Query: 125 CVASNIYGTVN 135
C A N G+ +
Sbjct: 3652 CTARNAAGSTS 3662
Score = 32.3 bits (72), Expect = 0.80
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 11/104 (10%)
Query: 41 VVLGSVPVIIARTDHII-VKEGNSALINCSVY-GIPDPQFKWYNSIGKLLKEEEDEKERG 98
+V G P IA + + V EG + C V G P P+ W G+ L
Sbjct: 878 IVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKD-GRPLPP-------- 928
Query: 99 GGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G + + G L++ + G+Y+CVA+N G+ + V L V
Sbjct: 929 GSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV 972
Score = 31.6 bits (70), Expect = 1.4
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 13/89 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQMHDSGLLNITK 114
+V++G A + C+ G P P W E D + G G + L++ +
Sbjct: 2270 VVQDG-VATLECNATGKPPPTVTW----------ERDGQPVGAELGLQLQNQGQSLHVER 2318
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+ G+Y+CVA N+ G L V+
Sbjct: 2319 AQAAHTGRYSCVAENLAGRAERKFELSVL 2347
Score = 30.8 bits (68), Expect = 2.3
Identities = 24/97 (24%), Positives = 36/97 (37%), Gaps = 7/97 (7%)
Query: 61 GNSALINCSVYGIPDPQFKWYNS---IGKLLKEEEDEKERG----GGKWQMHDSGLLNIT 113
G S + C G P P+ W +G L + G GG + + L+
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 1374
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
++ D G Y+C A N GT L V+ +G
Sbjct: 1375 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLG 1411
Score = 29.6 bits (65), Expect = 5.2
Identities = 20/88 (22%), Positives = 31/88 (35%), Gaps = 12/88 (13%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
++V G+ + C G+P P W LL + + L + V
Sbjct: 3416 VVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS------------LEQGPSLQLEAV 3463
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVI 143
D G Y+CVA + G L V+
Sbjct: 3464 GAGDSGTYSCVAVSEAGEARRHFQLTVM 3491
Score = 28.9 bits (63), Expect = 8.8
Identities = 17/72 (23%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
G + C G P P W++ + + E E D +L + +
Sbjct: 1611 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLET--------DGSVLRLESPGEASS 1662
Query: 121 GKYTCVASNIYG 132
G Y+CVAS+ G
Sbjct: 1663 GLYSCVASSPAG 1674
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 53.1 bits (126), Expect = 4e-07
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D ++V+ G+ A+++C +P+P WY L+ + + RGG + L I
Sbjct: 1758 DAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR--------LEIQ 1809
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD+G Y+C SN+ G T TL V
Sbjct: 1810 EAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1838
Score = 52.4 bits (124), Expect = 7e-07
Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 12/121 (9%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L AK+ S + T +V+ PVI + EG+ A + C G P+P W
Sbjct: 2734 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITW---- 2789
Query: 85 GKLLKEEEDEKERGG--GKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
++D + G GK+ + SG L + + D G YTC A N G V L +
Sbjct: 2790 ------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843
Query: 143 I 143
+
Sbjct: 2844 L 2844
Score = 45.8 bits (107), Expect = 7e-05
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
TA++ ST V + +VP I + + V +AL+ C G+P P W
Sbjct: 2371 TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW------ 2424
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+++ + ++++ G L I V D G Y C+ASN G+ LRV+
Sbjct: 2425 --RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 2479
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 13/107 (12%)
Query: 40 NVVLGSVPVIIARTDHII-VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
N+ + PV R H + V+EG+ ++C G+P P+ W ++ + G
Sbjct: 873 NLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISW---------RKDGQPLPG 923
Query: 99 GGKWQMHDSG---LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G H S LL + + + G YTC SN+ G + + L V
Sbjct: 924 EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEV 970
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I V +G +A + C+V G P P+ W+ G+ L RG D LL + +
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKD-GRPLA-------RGDAHHISPDGVLLQVLQA 1224
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ S G Y+C+A+N G L V+ +G
Sbjct: 1225 NLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 1259
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 41 VVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGG 100
+VL S PV + V+ G+ + C G P P +W + + R
Sbjct: 3021 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL---------QAGQPLRASR 3071
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGT 133
+ + G L + V D G Y CVA N+ G+
Sbjct: 3072 RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGS 3104
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T + V E + + C G+P P W+ L + RGG + L +
Sbjct: 227 TGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQ--------LQL 278
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ SD G YTC ASN G L V
Sbjct: 279 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 8/85 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
V E S + C G+P P W+ G D +L I +
Sbjct: 615 VLENASVTLECLASGVPPPDVSWFKG--------HQPVSSWMGVTVSVDGRVLRIEQAQL 666
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y CVASN+ G+ LRV
Sbjct: 667 SDAGSYRCVASNVAGSTELRYGLRV 691
Score = 39.3 bits (90), Expect = 0.007
Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 8/86 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P+ + K ++ + C + +P P +WY G+ + + G G+
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKD-GQPVTPSSRLQVLGEGR----- 1411
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYG 132
LL I SD G+Y CVA+N+ G
Sbjct: 1412 --LLQIQPTQVSDSGRYLCVATNVAG 1435
Score = 38.5 bits (88), Expect = 0.011
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 53 TDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
T++ + E N A + C IP P WY L +E +GG +L I
Sbjct: 1475 TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGG--------RVLQI 1526
Query: 113 TKVSFSDRGKYTCVASNIYG 132
V + G+Y+C ASN G
Sbjct: 1527 PLVRAENAGRYSCKASNEVG 1546
Score = 37.7 bits (86), Expect = 0.019
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 68 CSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVA 127
C GIP P +W+ E+ G + + +L +T+ D G Y+C+A
Sbjct: 1092 CEAMGIPPPAIRWFRG--------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1143
Query: 128 SNIYGTVNNTVTLRVI 143
SN G ++ V+
Sbjct: 1144 SNEAGEARRNFSVEVL 1159
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 10/95 (10%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSG 108
+AR H++ EG ++C G P P W LK+ + G + + D G
Sbjct: 1941 VAREHHVL--EGQEVRLDCEADGQPPPDVAW-------LKDGSPLGQDMGPHLRFYLDGG 1991
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L + + SD G YTCVA N G T+ V+
Sbjct: 1992 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 2026
Score = 36.2 bits (82), Expect = 0.055
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 8/82 (9%)
Query: 62 NSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRG 121
+S + C V+ P+P+ WY L EE + + + L + + SD G
Sbjct: 1671 SSVSLPCDVHAHPNPEVTWYKDSQALSLGEE--------VFLLPGTHTLQLGRARLSDSG 1722
Query: 122 KYTCVASNIYGTVNNTVTLRVI 143
YTC A N G V L V+
Sbjct: 1723 MYTCEALNAAGRDQKLVQLSVL 1744
Score = 35.8 bits (81), Expect = 0.072
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 9/83 (10%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSD 119
G + C G+P PQ +W +L GG Q+ + G +L IT D
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLP--------GGPHLQVQEDGQVLRITGSHVGD 192
Query: 120 RGKYTCVASNIYGTVNNTVTLRV 142
G+Y CVA + G LRV
Sbjct: 193 EGRYQCVAFSPAGQQARDFQLRV 215
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 9/86 (10%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+++ G S ++C V G P P W L RG +G L I +
Sbjct: 2945 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL---------RGSHLRHQLQNGSLTIRR 2995
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTL 140
D G+Y C+A N G V L
Sbjct: 2996 TERDDAGRYQCLAENEMGVAKKVVIL 3021
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 12/100 (12%)
Query: 47 PVIIARTDHII----VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
PVI+ T+ ++ V ++ + C G P P W + +
Sbjct: 1560 PVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV------- 1612
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D +L ++ +D Y CVA N G+ TLRV
Sbjct: 1613 -LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 1651
Score = 34.7 bits (78), Expect = 0.16
Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 9/78 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
L+ C GIP P W ++E G Q+ G L I S D G Y
Sbjct: 2684 LLPCEASGIPRPTITW---------QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYL 2734
Query: 125 CVASNIYGTVNNTVTLRV 142
C+A N G+ L V
Sbjct: 2735 CIAKNSAGSAMGKTRLVV 2752
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 66 INCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITKVSFSDRGKYT 124
+ C+ G P P W LK+ G Q+ G +L + SD G+Y+
Sbjct: 715 LTCNATGAPSPTLMW-------LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYS 767
Query: 125 CVASNIYGTVNNTVTLRV 142
CVA + G V L+V
Sbjct: 768 CVAVSAVGEDRQDVVLQV 785
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 8/96 (8%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ ++ V S + C + +P P W+ G+ L+ G D
Sbjct: 789 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKD-GRPLEPRP-------GVHLSAD 840
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
LL + + D G YTC A N G L V
Sbjct: 841 KALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 10/88 (11%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG-LLNITK 114
++ + G + C V G P W L + + +H SG L I+K
Sbjct: 2041 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQ---------RTLLHGSGHTLRISK 2091
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRV 142
V +D G +TCVA++ G + TL+V
Sbjct: 2092 VQLADAGIFTCVAASPAGVADRNFTLQV 2119
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ C GIP P W + +L RG G +++ SG L I + G+YT
Sbjct: 2593 VLTCHSTGIPAPTVSWSKAGAQL-------GARGSG-YRVSPSGALEIGQALPIHAGRYT 2644
Query: 125 CVASNIYGTVNNTVTLRV 142
C A N G + V L V
Sbjct: 2645 CSARNSAGVAHKHVFLTV 2662
Score = 33.5 bits (75), Expect = 0.36
Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 8/126 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSI 84
L A + S G ++ + P I ++ + AL+ C G P P W+
Sbjct: 2460 LCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2519
Query: 85 GKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNN--TVTLRV 142
KL + G +++ S L +T D ++ CV SN G + VT+ V
Sbjct: 2520 QKL------DFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 2573
Query: 143 IFTSGD 148
T D
Sbjct: 2574 PPTIAD 2579
Score = 33.1 bits (74), Expect = 0.47
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I KV D G YTC A+N+ G V L+V+
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 601
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 8/92 (8%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLN 111
+T+ + G+ ++ C V G+P P W ++ E + G L
Sbjct: 1848 KTETVSQVAGSPLVLTCDVSGVPAPTVTWL--------KDRMPVESSAVHGVVSRGGRLQ 1899
Query: 112 ITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
++++ + G YTCVA N + V+
Sbjct: 1900 LSRLQPAQAGTYTCVAENTQAEARKDFVVAVL 1931
Score = 32.7 bits (73), Expect = 0.61
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 65 LINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYT 124
++ CSV P P+ W+ G +L+E+ + G++ L + +S +D G Y+
Sbjct: 2318 VLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERGRF-------LQLQALSTADSGDYS 2369
Query: 125 CVASNIYGTVN 135
C A N G+ +
Sbjct: 2370 CTARNAAGSTS 2380
Score = 31.6 bits (70), Expect = 1.4
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 13/89 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQMHDSGLLNITK 114
+V++G A + C+ G P P W E D + G G + L++ +
Sbjct: 988 VVQDG-VATLECNATGKPPPTVTW----------ERDGQPVGAELGLQLQNQGQSLHVER 1036
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
+ G+Y+CVA N+ G L V+
Sbjct: 1037 AQAAHTGRYSCVAENLAGRAERKFELSVL 1065
Score = 30.8 bits (68), Expect = 2.3
Identities = 24/97 (24%), Positives = 36/97 (37%), Gaps = 7/97 (7%)
Query: 61 GNSALINCSVYGIPDPQFKWYNS---IGKLLKEEEDEKERG----GGKWQMHDSGLLNIT 113
G S + C G P P+ W +G L + G GG + + L+
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
++ D G Y+C A N GT L V+ +G
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLG 129
Score = 29.6 bits (65), Expect = 5.2
Identities = 20/88 (22%), Positives = 31/88 (35%), Gaps = 12/88 (13%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
++V G+ + C G+P P W LL + + L + V
Sbjct: 2134 VVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS------------LEQGPSLQLEAV 2181
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVI 143
D G Y+CVA + G L V+
Sbjct: 2182 GAGDSGTYSCVAVSEAGEARRHFQLTVM 2209
Score = 28.9 bits (63), Expect = 8.8
Identities = 17/72 (23%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 61 GNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
G + C G P P W++ + + E E D +L + +
Sbjct: 329 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLET--------DGSVLRLESPGEASS 380
Query: 121 GKYTCVASNIYG 132
G Y+CVAS+ G
Sbjct: 381 GLYSCVASSPAG 392
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 272
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 273 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 84
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 132
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 123 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 181
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 182 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 208
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 449
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 450 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 496
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 272
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 273 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 84
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 132
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 123 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 181
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 182 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 208
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 449
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 450 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 496
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 272
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 273 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 84
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 132
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 123 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 181
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 182 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 208
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 388 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 446
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 447 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 493
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
+ K+ T++ L VV + PVI + + + V G+ A C + P+ +F+W+ + +
Sbjct: 4512 SGKTATSAKLT---VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4568
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTS 146
+ E D+ K+ L I + D G+YTC ASN YG+V+ T TL V
Sbjct: 4569 IY--ESDKCSIRSSKY----ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPG 4622
Query: 147 GDMGV 151
G+ V
Sbjct: 4623 GEKKV 4627
Score = 48.9 bits (115), Expect = 8e-06
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 44 GSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQ 103
G+ P+ I + + G+ A ++ +V GIP P+ +W+ + G LL D K G
Sbjct: 3646 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDG--- 3701
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
D L I D G+YTC+ASN YG + L++
Sbjct: 3702 --DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 39 TNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
T + G P I + K G +A ++C + G P P KWY GK L + K
Sbjct: 24220 TKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSS 24278
Query: 99 GGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
G+ + L + D G YTC+A+N G V + L
Sbjct: 24279 DGR-----THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24315
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 6/101 (5%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
L P I++ + EG + L C + G P P+ +W+ + + R +
Sbjct: 26825 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26884
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I S SD GKYT A N G + T +L V+
Sbjct: 26885 S------LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26919
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM-H 105
P +++ ++ V EG S + C + G P P WY ED + +Q+
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY---------REDYQIESSIDFQITF 947
Query: 106 DSGL--LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
SG+ L I + D G++TC A N GTV+ + L V
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P II + EG A C V G D + WY+ K+++ + R Q D
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYS------KDKKIKPSRFFRMTQFED 3351
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
+ L I + D G YT VASN G V++T L
Sbjct: 3352 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 6/102 (5%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH 105
+ + +A + VK G + ++ +V+G P P W G LLK E K
Sbjct: 12990 IDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMA-----MQR 13043
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ L + V+ D G YT A N G+ + T+ L+V+ G
Sbjct: 13044 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG 13085
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
T +VT T + S PVI+ V + A G P P W GK
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GK 26585
Query: 87 LLKEEEDEKERGGGKWQM-HDSG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ + GGK+++ D G L I K SD G YTC N G+V+++ L +
Sbjct: 26586 AITQ--------GGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26636
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ + + V EG +A C V G P P+ WY + G+L+++ + + R G +H
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDG---IH- 1849
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I D G+ A N G + + V L +
Sbjct: 1850 --YLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 38.1 bits (87), Expect = 0.015
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQ 103
+P I + I +K G I VYG P P KW K+ EDE +
Sbjct: 12593 LPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW--------KKGEDEVVTSSHLAVHK 12644
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S +L I V+ D G Y+ A N GT + + V+ G
Sbjct: 12645 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12688
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEE------DEKERGGGKWQMH 105
R D I VK G I V G+P P+ +W + + K + +E R K +
Sbjct: 9099 RGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-- 9156
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I K D+G YT ASN G+V V + V
Sbjct: 9157 ----LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I+V+ G SA I+ G P P+ W G+ + + EK G Q L+I
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK--GVNYTQ------LSIDNC 17780
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D GKY N G+ + VT++V+ T G
Sbjct: 17781 DRNDAGKYILKLENSSGSKSAFVTVKVLDTPG 17812
Score = 37.4 bits (85), Expect = 0.025
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
Query: 26 ATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIG 85
A S ++T+ + +P I + + V+EG + I + G+P P W+ +
Sbjct: 9791 AAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPP 9850
Query: 86 KLLKEEEDE-KERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIF 144
K +E + K + D+ L I + SD G YT A N GT + + L V+
Sbjct: 9851 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9910
Query: 145 TSG 147
G
Sbjct: 9911 RPG 9913
Score = 37.4 bits (85), Expect = 0.025
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
+I K G++ + V G P P W L + + E S +LNI +
Sbjct: 14770 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTA------TSTILNINEC 14823
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y A NI G V + +T++V
Sbjct: 14824 VRSDSGPYPLTARNIVGEVGDVITIQV 14850
Score = 36.6 bits (83), Expect = 0.042
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 22 VSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
+S + +S T+ L + G P I A I + EG + C+ G P P+ W
Sbjct: 27001 ISNMTQLESSTSKMLKAG--IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS 27058
Query: 82 NSIGKLLKEEEDEKERGGGKWQMH---DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTV 138
K+ +E+ G++ + D L I V D G YT N +G+ + TV
Sbjct: 27059 CGGRKIHSQEQ-------GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 27111
Query: 139 TLRV 142
+ +
Sbjct: 27112 NIHI 27115
Score = 35.8 bits (81), Expect = 0.072
Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 6/101 (5%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I T IIV EG I +P P W+ GK +K + + H
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD-GKEVKASDRLTMKND-----HI 8135
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S L + K +D G YT N G+ ++ ++VI G
Sbjct: 8136 SAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 8176
Score = 35.4 bits (80), Expect = 0.094
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 51 ARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM----HD 106
+R + + EG +C + G P P+ WY GK +K G ++QM
Sbjct: 1249 SRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKD-GKRIKH--------GERYQMDFLQDG 1299
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYG 132
L I V D G YT ASNI G
Sbjct: 1300 RASLRIPVVLPEDEGIYTAFASNIKG 1325
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 14/95 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+ KE ++ + + G P P W L + E S +N T +
Sbjct: 13688 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE----------SSAVNTTLIV 13737
Query: 117 F----SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ SD GKYT N+ GT T++++V+ G
Sbjct: 13738 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPG 13772
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 54 DHIIVKEGNSALINC-SVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
D + +K G++ ++N S+ G P P+ W + GK ++ + + S +L I
Sbjct: 14081 DGLTIKAGDTIVLNAISILGKPLPKSSW-SKAGKDIRPSDITQITS-----TPTSSMLTI 14134
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ D G+YT A+N +GT V + V+ G G
Sbjct: 14135 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPG 14172
Score = 34.7 bits (78), Expect = 0.16
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++ + V+ G A + G P P+ WY +EE G +HD
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY--------KEEQLLSTGFKCKFLHD 3244
Query: 107 SG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L + + D YTC A N YG + +L V
Sbjct: 3245 GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 74 PDPQFKWYNSIGKLLKEEEDEK---ERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNI 130
P+P WY S K+ + D+K E G +Q L I V+ D +YT VA N
Sbjct: 25412 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ------LTINSVTTDDDAEYTVVARNK 25465
Query: 131 YG 132
YG
Sbjct: 25466 YG 25467
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 6/93 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSGLLNITK 114
+ VK G++ + V G P P+ W K+ D K DS ++TK
Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKD-----KDATDLTRSPRVKIDTRADSSKFSLTK 11960
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
SD GKY A+N G+ T+ V+ G
Sbjct: 11961 AKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11993
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D + ++ G+ +++ +V G P+P+ W +E D E K + +G
Sbjct: 22750 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKG-----DKELDLCE----KVSLQYTGKRATA 22800
Query: 114 KVSFSDR---GKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ F DR GKYT N GT +V ++V+ + G G
Sbjct: 22801 VIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCG 22840
Score = 33.5 bits (75), Expect = 0.36
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 6/103 (5%)
Query: 45 SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM 104
SV + + + ++VK G + + G+P P KW ++ +E E
Sbjct: 11204 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD------ 11257
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ S +L I D G+Y SN G+ V L V+ G
Sbjct: 11258 NFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPG 11300
Score = 33.5 bits (75), Expect = 0.36
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 6/94 (6%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D +I+K G S I V G P P+ W+ E EK + S L +
Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFKD------GVEIEKRMNMEITDVLGSTSLFVR 21714
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ RG YT A N G+ + ++V T G
Sbjct: 21715 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748
Score = 33.1 bits (74), Expect = 0.47
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R + V++G+ + V GIP P K+Y ++ + + + G D
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG------D 157
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I + D G Y+ A+N G +T L V
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 33.1 bits (74), Expect = 0.47
Identities = 26/99 (26%), Positives = 38/99 (38%), Gaps = 6/99 (6%)
Query: 44 GSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQ 103
G P I + VK G++A C + W + G ++E E K+ G Q
Sbjct: 3486 GEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHE-GAKIEESERLKQSQNGNIQ 3544
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I V D+G Y+C+ N G + L V
Sbjct: 3545 F-----LTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 3578
Score = 32.7 bits (73), Expect = 0.61
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 26/99 (26%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK- 114
I ++ G S + + G P P+ KW G++ D+ ++++T
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----------------RDAAIIDVTSS 16689
Query: 115 --------VSFSDRGKYTCVASNIYGTVNNTVTLRVIFT 145
V+ D GKYT N GT + VT+RV+ T
Sbjct: 16690 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16728
Score = 32.3 bits (72), Expect = 0.80
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + + V+G P P +W L+ +++ +E + + D L I
Sbjct: 17328 DTIVVNAGETFRLEADVHGKPLPTIEW-------LRGDKEIEESARCEIKNTDFKALLIV 17380
Query: 114 KVSFS-DRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
K + D G+Y ASN+ G+ + V ++V+ G
Sbjct: 17381 KDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPG 17415
Score = 32.0 bits (71), Expect = 1.0
Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 8/121 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLG---SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
LA +T T + L P I R V +G+ A V G PDP+ +WY
Sbjct: 2007 LAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWY 2066
Query: 82 NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLR 141
+ K+ + +R W + L I V+ D A NI G ++ L
Sbjct: 2067 KNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2121
Query: 142 V 142
V
Sbjct: 2122 V 2122
Score = 32.0 bits (71), Expect = 1.0
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD-SGLLNI 112
D I+V G S ++ +YG P P +W +K +++ + + D + L++
Sbjct: 16246 DTIVVHAGESFKVDADIYGKPIPTIQW-------IKGDQELSNTARLEIKSTDFATSLSV 16298
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G Y A N+ G + TV ++V+ G
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG 16333
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNS-IGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+ ++ G S + SV G P P W I + D E LL + K
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE---------SYSLLIVDK 23201
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
V+ D GKYT A N G + TV ++V T G
Sbjct: 23202 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 23234
Score = 32.0 bits (71), Expect = 1.0
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKE--EEDEKERGGGKWQMHDSGLLNITKV 115
V+ ++A + C V G P P KWY +++ + + +E GG Q L I V
Sbjct: 24634 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ------LIIASV 24687
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D Y A+N G+V+ T +L V
Sbjct: 24688 TDDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 31.6 bits (70), Expect = 1.4
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
++ G I V G P P W G+ LK+ + S +L+I + +
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVE-----ETATSTVLHIKEGNK 18071
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D GKYT A+N GT +++ V+ G
Sbjct: 18072 DDFGKYTVTATNSAGTATENLSVIVLEKPG 18101
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNI 112
D I+VK G IN + G P P W K+ + +ER + D+ LL +
Sbjct: 19492 DVIVVKAGEVLKINADIAGRPLPVISW-------AKDGIEIEERARTEIISTDNHTLLTV 19544
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G+Y N+ GT + V +V+ G
Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG 19579
Score = 31.6 bits (70), Expect = 1.4
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 15/101 (14%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG-GKWQMHD-- 106
+A +I K G + G P P W +DEK G ++ + +
Sbjct: 20970 VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW----------RKDEKNLGSDARYSIENTD 21019
Query: 107 -SGLLNITKVSFSDRGKYTCVASNIYG-TVNNTVTLRVIFT 145
S LL I +V+ +D GKY N G ++TV+++V+ T
Sbjct: 21020 SSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 21060
Score = 31.2 bits (69), Expect = 1.8
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++V EG++A + G P P+ W+ G+++ G + D
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRD-GQVI----STSTLPGVQISFSD 60
Query: 107 S-GLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I V+ ++ G+Y+ A+N G +T L V
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 30.8 bits (68), Expect = 2.3
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + ++ + G P P W K KE E+ R K + + L+ +
Sbjct: 18410 DVIVVHAGETFVLEADIRGKPIPDVVW----SKDGKELEETAARMEIKSTIQKTTLV-VK 18464
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D G+Y SN+ GT + +T++V+ G
Sbjct: 18465 DCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG 18498
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNITK 114
I V G + + G P P W+ + KL + E E H L I +
Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVET-------HTKVAKLTIRE 23495
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ D G+YT N+ GT + T+ + ++ G
Sbjct: 23496 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPG 23528
Score = 30.8 bits (68), Expect = 2.3
Identities = 24/94 (25%), Positives = 34/94 (36%), Gaps = 6/94 (6%)
Query: 49 IIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG 108
I+ + + V EG SA +C G P P W G++L +
Sbjct: 26258 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVT-----TTKYKS 26311
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
I+ V SD G Y+ V N G TL +
Sbjct: 26312 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26345
Score = 30.4 bits (67), Expect = 3.0
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 70 VYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASN 129
+ G P P+ KW G+ L + E LL + V+ D GKY N
Sbjct: 15579 IKGRPAPEVKWARDHGESLDKASIESTSS--------YTLLIVGNVNRFDSGKYILTVEN 15630
Query: 130 IYGTVNNTVTLRVIFTSG 147
G+ + V +RV+ T G
Sbjct: 15631 SSGSKSAFVNVRVLDTPG 15648
Score = 30.0 bits (66), Expect = 4.0
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 11/99 (11%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDE---KERGGGKWQ 103
PV + + EG +A + V G P P+ W++ +++ + + KE G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG----- 1465
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ L I + SD G++T VA N G + +V L V
Sbjct: 1466 ---TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 30.0 bits (66), Expect = 4.0
Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGL-LNITK 114
+IVK G S + G P P W + D R DS L I
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLW---------SKPDTDLRTRAYVDTTDSRTSLTIEN 19941
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ +D GKYT N+ + T+ ++V+ T G
Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG 19974
Score = 28.9 bits (63), Expect = 8.8
Identities = 29/124 (23%), Positives = 48/124 (38%), Gaps = 24/124 (19%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEK-----ERGGGK 101
P +I RT + VK G+ ++ S+ G P P W ++ EE ++ R G+
Sbjct: 8376 PKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGE 8434
Query: 102 WQMHDSGLLNIT-KVSFS-----------------DRGKYTCVASNIYGTVNNTVTLRVI 143
Q + +L +T ++S D G Y N +G T+ V+
Sbjct: 8435 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8494
Query: 144 FTSG 147
T G
Sbjct: 8495 DTPG 8498
Score = 28.9 bits (63), Expect = 8.8
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
L + + +D GKYT N G+ + T T++V+ T G G
Sbjct: 22108 LTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22148
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
+ K+ T++ L VV + PVI + + + V G+ A C + P+ +F+W+ + +
Sbjct: 4445 SGKTATSAKLT---VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4501
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTS 146
+ E D+ K+ L I + D G+YTC ASN YG+V+ T TL V
Sbjct: 4502 IY--ESDKCSIRSSKY----ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPG 4555
Query: 147 GDMGV 151
G+ V
Sbjct: 4556 GEKKV 4560
Score = 48.9 bits (115), Expect = 8e-06
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 44 GSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQ 103
G+ P+ I + + G+ A ++ +V GIP P+ +W+ + G LL D K G
Sbjct: 3579 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDG--- 3634
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
D L I D G+YTC+ASN YG + L++
Sbjct: 3635 --DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3671
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 39 TNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
T + G P I + K G +A ++C + G P P KWY GK L + K
Sbjct: 24153 TKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSS 24211
Query: 99 GGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
G+ + L + D G YTC+A+N G V + L
Sbjct: 24212 DGR-----THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24248
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 6/101 (5%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
L P I++ + EG + L C + G P P+ +W+ + + R +
Sbjct: 26758 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26817
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I S SD GKYT A N G + T +L V+
Sbjct: 26818 S------LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26852
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM-H 105
P +++ ++ V EG S + C + G P P WY ED + +Q+
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY---------REDYQIESSIDFQITF 947
Query: 106 DSGL--LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
SG+ L I + D G++TC A N GTV+ + L V
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P II + EG A C V G D + WY+ K+++ + R Q D
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYS------KDKKIKPSRFFRMTQFED 3351
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
+ L I + D G YT VASN G V++T L
Sbjct: 3352 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 6/102 (5%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH 105
+ + +A + VK G + ++ +V+G P P W G LLK E K
Sbjct: 12923 IDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMA-----MQR 12976
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ L + V+ D G YT A N G+ + T+ L+V+ G
Sbjct: 12977 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG 13018
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
T +VT T + S PVI+ V + A G P P W GK
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GK 26518
Query: 87 LLKEEEDEKERGGGKWQM-HDSG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ + GGK+++ D G L I K SD G YTC N G+V+++ L +
Sbjct: 26519 AITQ--------GGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26569
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ + + V EG +A C V G P P+ WY + G+L+++ + + R G +H
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDG---IH- 1849
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I D G+ A N G + + V L +
Sbjct: 1850 --YLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 38.1 bits (87), Expect = 0.015
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQ 103
+P I + I +K G I VYG P P KW K+ EDE +
Sbjct: 12526 LPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW--------KKGEDEVVTSSHLAVHK 12577
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S +L I V+ D G Y+ A N GT + + V+ G
Sbjct: 12578 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12621
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEE------DEKERGGGKWQMH 105
R D I VK G I V G+P P+ +W + + K + +E R K +
Sbjct: 9032 RGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-- 9089
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I K D+G YT ASN G+V V + V
Sbjct: 9090 ----LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I+V+ G SA I+ G P P+ W G+ + + EK G Q L+I
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK--GVNYTQ------LSIDNC 17713
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D GKY N G+ + VT++V+ T G
Sbjct: 17714 DRNDAGKYILKLENSSGSKSAFVTVKVLDTPG 17745
Score = 37.4 bits (85), Expect = 0.025
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
Query: 26 ATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIG 85
A S ++T+ + +P I + + V+EG + I + G+P P W+ +
Sbjct: 9724 AAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPP 9783
Query: 86 KLLKEEEDE-KERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIF 144
K +E + K + D+ L I + SD G YT A N GT + + L V+
Sbjct: 9784 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9843
Query: 145 TSG 147
G
Sbjct: 9844 RPG 9846
Score = 37.4 bits (85), Expect = 0.025
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
+I K G++ + V G P P W L + + E S +LNI +
Sbjct: 14703 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTA------TSTILNINEC 14756
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y A NI G V + +T++V
Sbjct: 14757 VRSDSGPYPLTARNIVGEVGDVITIQV 14783
Score = 36.6 bits (83), Expect = 0.042
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 22 VSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
+S + +S T+ L + G P I A I + EG + C+ G P P+ W
Sbjct: 26934 ISNMTQLESSTSKMLKAG--IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS 26991
Query: 82 NSIGKLLKEEEDEKERGGGKWQMH---DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTV 138
K+ +E+ G++ + D L I V D G YT N +G+ + TV
Sbjct: 26992 CGGRKIHSQEQ-------GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 27044
Query: 139 TLRV 142
+ +
Sbjct: 27045 NIHI 27048
Score = 35.8 bits (81), Expect = 0.072
Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 6/101 (5%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I T IIV EG I +P P W+ GK +K + + H
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD-GKEVKASDRLTMKND-----HI 8068
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S L + K +D G YT N G+ ++ ++VI G
Sbjct: 8069 SAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 8109
Score = 35.4 bits (80), Expect = 0.094
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 51 ARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM----HD 106
+R + + EG +C + G P P+ WY GK +K G ++QM
Sbjct: 1249 SRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKD-GKRIKH--------GERYQMDFLQDG 1299
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYG 132
L I V D G YT ASNI G
Sbjct: 1300 RASLRIPVVLPEDEGIYTAFASNIKG 1325
Score = 35.4 bits (80), Expect = 0.094
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 8/102 (7%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLL--KEEEDEKERGGG 100
LG P I + V G + + V GIP P+ +W+++ +L K+ E G
Sbjct: 3415 LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTG 3474
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+ I G+Y+C A+N G TL V
Sbjct: 3475 ------MALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 14/95 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+ KE ++ + + G P P W L + E S +N T +
Sbjct: 13621 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE----------SSAVNTTLIV 13670
Query: 117 F----SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ SD GKYT N+ GT T++++V+ G
Sbjct: 13671 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPG 13705
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 54 DHIIVKEGNSALINC-SVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
D + +K G++ ++N S+ G P P+ W + GK ++ + + S +L I
Sbjct: 14014 DGLTIKAGDTIVLNAISILGKPLPKSSW-SKAGKDIRPSDITQITS-----TPTSSMLTI 14067
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ D G+YT A+N +GT V + V+ G G
Sbjct: 14068 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPG 14105
Score = 34.7 bits (78), Expect = 0.16
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++ + V+ G A + G P P+ WY +EE G +HD
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY--------KEEQLLSTGFKCKFLHD 3244
Query: 107 SG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L + + D YTC A N YG + +L V
Sbjct: 3245 GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 74 PDPQFKWYNSIGKLLKEEEDEK---ERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNI 130
P+P WY S K+ + D+K E G +Q L I V+ D +YT VA N
Sbjct: 25345 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ------LTINSVTTDDDAEYTVVARNK 25398
Query: 131 YG 132
YG
Sbjct: 25399 YG 25400
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 6/93 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSGLLNITK 114
+ VK G++ + V G P P+ W K+ D K DS ++TK
Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKD-----KDATDLTRSPRVKIDTRADSSKFSLTK 11893
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
SD GKY A+N G+ T+ V+ G
Sbjct: 11894 AKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11926
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D + ++ G+ +++ +V G P+P+ W +E D E K + +G
Sbjct: 22683 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKG-----DKELDLCE----KVSLQYTGKRATA 22733
Query: 114 KVSFSDR---GKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ F DR GKYT N GT +V ++V+ + G G
Sbjct: 22734 VIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCG 22773
Score = 33.5 bits (75), Expect = 0.36
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 6/103 (5%)
Query: 45 SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM 104
SV + + + ++VK G + + G+P P KW ++ +E E
Sbjct: 11137 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD------ 11190
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ S +L I D G+Y SN G+ V L V+ G
Sbjct: 11191 NFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPG 11233
Score = 33.5 bits (75), Expect = 0.36
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 6/94 (6%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D +I+K G S I V G P P+ W+ E EK + S L +
Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFKD------GVEIEKRMNMEITDVLGSTSLFVR 21647
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ RG YT A N G+ + ++V T G
Sbjct: 21648 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681
Score = 33.1 bits (74), Expect = 0.47
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R + V++G+ + V GIP P K+Y ++ + + + G D
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG------D 157
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I + D G Y+ A+N G +T L V
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 32.7 bits (73), Expect = 0.61
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 26/99 (26%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK- 114
I ++ G S + + G P P+ KW G++ D+ ++++T
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----------------RDAAIIDVTSS 16622
Query: 115 --------VSFSDRGKYTCVASNIYGTVNNTVTLRVIFT 145
V+ D GKYT N GT + VT+RV+ T
Sbjct: 16623 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16661
Score = 32.3 bits (72), Expect = 0.80
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + + V+G P P +W L+ +++ +E + + D L I
Sbjct: 17261 DTIVVNAGETFRLEADVHGKPLPTIEW-------LRGDKEIEESARCEIKNTDFKALLIV 17313
Query: 114 KVSFS-DRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
K + D G+Y ASN+ G+ + V ++V+ G
Sbjct: 17314 KDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPG 17348
Score = 32.0 bits (71), Expect = 1.0
Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 8/121 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLG---SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
LA +T T + L P I R V +G+ A V G PDP+ +WY
Sbjct: 2007 LAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWY 2066
Query: 82 NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLR 141
+ K+ + +R W + L I V+ D A NI G ++ L
Sbjct: 2067 KNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2121
Query: 142 V 142
V
Sbjct: 2122 V 2122
Score = 32.0 bits (71), Expect = 1.0
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD-SGLLNI 112
D I+V G S ++ +YG P P +W +K +++ + + D + L++
Sbjct: 16179 DTIVVHAGESFKVDADIYGKPIPTIQW-------IKGDQELSNTARLEIKSTDFATSLSV 16231
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G Y A N+ G + TV ++V+ G
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG 16266
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNS-IGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+ ++ G S + SV G P P W I + D E LL + K
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE---------SYSLLIVDK 23134
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
V+ D GKYT A N G + TV ++V T G
Sbjct: 23135 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 23167
Score = 32.0 bits (71), Expect = 1.0
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKE--EEDEKERGGGKWQMHDSGLLNITKV 115
V+ ++A + C V G P P KWY +++ + + +E GG Q L I V
Sbjct: 24567 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ------LIIASV 24620
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D Y A+N G+V+ T +L V
Sbjct: 24621 TDDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 31.6 bits (70), Expect = 1.4
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
++ G I V G P P W G+ LK+ + S +L+I + +
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVE-----ETATSTVLHIKEGNK 18004
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D GKYT A+N GT +++ V+ G
Sbjct: 18005 DDFGKYTVTATNSAGTATENLSVIVLEKPG 18034
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNI 112
D I+VK G IN + G P P W K+ + +ER + D+ LL +
Sbjct: 19425 DVIVVKAGEVLKINADIAGRPLPVISW-------AKDGIEIEERARTEIISTDNHTLLTV 19477
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G+Y N+ GT + V +V+ G
Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG 19512
Score = 31.6 bits (70), Expect = 1.4
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 15/101 (14%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG-GKWQMHD-- 106
+A +I K G + G P P W +DEK G ++ + +
Sbjct: 20903 VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW----------RKDEKNLGSDARYSIENTD 20952
Query: 107 -SGLLNITKVSFSDRGKYTCVASNIYG-TVNNTVTLRVIFT 145
S LL I +V+ +D GKY N G ++TV+++V+ T
Sbjct: 20953 SSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 20993
Score = 31.2 bits (69), Expect = 1.8
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++V EG++A + G P P+ W+ G+++ G + D
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRD-GQVI----STSTLPGVQISFSD 60
Query: 107 S-GLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I V+ ++ G+Y+ A+N G +T L V
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 30.8 bits (68), Expect = 2.3
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + ++ + G P P W K KE E+ R K + + L+ +
Sbjct: 18343 DVIVVHAGETFVLEADIRGKPIPDVVW----SKDGKELEETAARMEIKSTIQKTTLV-VK 18397
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D G+Y SN+ GT + +T++V+ G
Sbjct: 18398 DCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG 18431
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNITK 114
I V G + + G P P W+ + KL + E E H L I +
Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVET-------HTKVAKLTIRE 23428
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ D G+YT N+ GT + T+ + ++ G
Sbjct: 23429 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPG 23461
Score = 30.8 bits (68), Expect = 2.3
Identities = 24/94 (25%), Positives = 34/94 (36%), Gaps = 6/94 (6%)
Query: 49 IIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG 108
I+ + + V EG SA +C G P P W G++L +
Sbjct: 26191 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVT-----TTKYKS 26244
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
I+ V SD G Y+ V N G TL +
Sbjct: 26245 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26278
Score = 30.4 bits (67), Expect = 3.0
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 70 VYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASN 129
+ G P P+ KW G+ L + E LL + V+ D GKY N
Sbjct: 15512 IKGRPAPEVKWARDHGESLDKASIESTSS--------YTLLIVGNVNRFDSGKYILTVEN 15563
Query: 130 IYGTVNNTVTLRVIFTSG 147
G+ + V +RV+ T G
Sbjct: 15564 SSGSKSAFVNVRVLDTPG 15581
Score = 30.0 bits (66), Expect = 4.0
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 11/99 (11%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDE---KERGGGKWQ 103
PV + + EG +A + V G P P+ W++ +++ + + KE G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG----- 1465
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ L I + SD G++T VA N G + +V L V
Sbjct: 1466 ---TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 30.0 bits (66), Expect = 4.0
Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGL-LNITK 114
+IVK G S + G P P W + D R DS L I
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLW---------SKPDTDLRTRAYVDTTDSRTSLTIEN 19874
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ +D GKYT N+ + T+ ++V+ T G
Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG 19907
Score = 28.9 bits (63), Expect = 8.8
Identities = 29/124 (23%), Positives = 48/124 (38%), Gaps = 24/124 (19%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEK-----ERGGGK 101
P +I RT + VK G+ ++ S+ G P P W ++ EE ++ R G+
Sbjct: 8309 PKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGE 8367
Query: 102 WQMHDSGLLNIT-KVSFS-----------------DRGKYTCVASNIYGTVNNTVTLRVI 143
Q + +L +T ++S D G Y N +G T+ V+
Sbjct: 8368 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8427
Query: 144 FTSG 147
T G
Sbjct: 8428 DTPG 8431
Score = 28.9 bits (63), Expect = 8.8
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
L + + +D GKYT N G+ + T T++V+ T G G
Sbjct: 22041 LTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22081
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
+ K+ T++ L VV + PVI + + + V G+ A C + P+ +F+W+ + +
Sbjct: 4320 SGKTATSAKLT---VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4376
Query: 87 LLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTS 146
+ E D+ K+ L I + D G+YTC ASN YG+V+ T TL V
Sbjct: 4377 IY--ESDKCSIRSSKY----ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPG 4430
Query: 147 GDMGV 151
G+ V
Sbjct: 4431 GEKKV 4435
Score = 48.9 bits (115), Expect = 8e-06
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 44 GSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQ 103
G+ P+ I + + G+ A ++ +V GIP P+ +W+ + G LL D K G
Sbjct: 3454 GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDG--- 3509
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
D L I D G+YTC+ASN YG + L++
Sbjct: 3510 --DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 39 TNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG 98
T + G P I + K G +A ++C + G P P KWY GK L + K
Sbjct: 24028 TKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSS 24086
Query: 99 GGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
G+ + L + D G YTC+A+N G V + L
Sbjct: 24087 DGR-----THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 6/101 (5%)
Query: 43 LGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKW 102
L P I++ + EG + L C + G P P+ +W+ + + R +
Sbjct: 26633 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26692
Query: 103 QMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143
L I S SD GKYT A N G + T +L V+
Sbjct: 26693 S------LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM-H 105
P +++ ++ V EG S + C + G P P WY ED + +Q+
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY---------REDYQIESSIDFQITF 947
Query: 106 DSGL--LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
SG+ L I + D G++TC A N GTV+ + L V
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P II + EG A C V G D + WY+ K+++ + R Q D
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYS------KDKKIKPSRFFRMTQFED 3351
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTL 140
+ L I + D G YT VASN G V++T L
Sbjct: 3352 TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 6/102 (5%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH 105
+ + +A + VK G + ++ +V+G P P W G LLK E K
Sbjct: 12798 IDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMA-----MQR 12851
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ L + V+ D G YT A N G+ + T+ L+V+ G
Sbjct: 12852 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG 12893
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 27 TAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGK 86
T +VT T + S PVI+ V + A G P P W GK
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GK 26393
Query: 87 LLKEEEDEKERGGGKWQM-HDSG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ + GGK+++ D G L I K SD G YTC N G+V+++ L +
Sbjct: 26394 AITQ--------GGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ + + V EG +A C V G P P+ WY + G+L+++ + + R G +H
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDG---IH- 1849
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I D G+ A N G + + V L +
Sbjct: 1850 --YLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1883
Score = 38.1 bits (87), Expect = 0.015
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 46 VPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG--GKWQ 103
+P I + I +K G I VYG P P KW K+ EDE +
Sbjct: 12401 LPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW--------KKGEDEVVTSSHLAVHK 12452
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S +L I V+ D G Y+ A N GT + + V+ G
Sbjct: 12453 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
Query: 52 RTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEE------DEKERGGGKWQMH 105
R D I VK G I V G+P P+ +W + + K + +E R K +
Sbjct: 8907 RGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-- 8964
Query: 106 DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L+I K D+G YT ASN G+V V + V
Sbjct: 8965 ----LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
I+V+ G SA I+ G P P+ W G+ + + EK G Q L+I
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEK--GVNYTQ------LSIDNC 17588
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D GKY N G+ + VT++V+ T G
Sbjct: 17589 DRNDAGKYILKLENSSGSKSAFVTVKVLDTPG 17620
Score = 37.4 bits (85), Expect = 0.025
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
Query: 26 ATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIG 85
A S ++T+ + +P I + + V+EG + I + G+P P W+ +
Sbjct: 9599 AAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPP 9658
Query: 86 KLLKEEEDE-KERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIF 144
K +E + K + D+ L I + SD G YT A N GT + + L V+
Sbjct: 9659 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Query: 145 TSG 147
G
Sbjct: 9719 RPG 9721
Score = 37.4 bits (85), Expect = 0.025
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKV 115
+I K G++ + V G P P W L + + E S +LNI +
Sbjct: 14578 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTA------TSTILNINEC 14631
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
SD G Y A NI G V + +T++V
Sbjct: 14632 VRSDSGPYPLTARNIVGEVGDVITIQV 14658
Score = 36.6 bits (83), Expect = 0.042
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 22 VSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
+S + +S T+ L + G P I A I + EG + C+ G P P+ W
Sbjct: 26809 ISNMTQLESSTSKMLKAG--IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS 26866
Query: 82 NSIGKLLKEEEDEKERGGGKWQMH---DSGLLNITKVSFSDRGKYTCVASNIYGTVNNTV 138
K+ +E+ G++ + D L I V D G YT N +G+ + TV
Sbjct: 26867 CGGRKIHSQEQ-------GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 26919
Query: 139 TLRV 142
+ +
Sbjct: 26920 NIHI 26923
Score = 35.8 bits (81), Expect = 0.072
Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 6/101 (5%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I T IIV EG I +P P W+ GK +K + + H
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD-GKEVKASDRLTMKND-----HI 7943
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
S L + K +D G YT N G+ ++ ++VI G
Sbjct: 7944 SAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 7984
Score = 35.4 bits (80), Expect = 0.094
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 51 ARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM----HD 106
+R + + EG +C + G P P+ WY GK +K G ++QM
Sbjct: 1249 SRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKD-GKRIKH--------GERYQMDFLQDG 1299
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYG 132
L I V D G YT ASNI G
Sbjct: 1300 RASLRIPVVLPEDEGIYTAFASNIKG 1325
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 14/95 (14%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+ KE ++ + + G P P W L + E S +N T +
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE----------SSAVNTTLIV 13545
Query: 117 F----SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ SD GKYT N+ GT T++++V+ G
Sbjct: 13546 YDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPG 13580
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 54 DHIIVKEGNSALINC-SVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNI 112
D + +K G++ ++N S+ G P P+ W + GK ++ + + S +L I
Sbjct: 13889 DGLTIKAGDTIVLNAISILGKPLPKSSW-SKAGKDIRPSDITQITS-----TPTSSMLTI 13942
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ D G+YT A+N +GT V + V+ G G
Sbjct: 13943 KYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPG 13980
Score = 34.7 bits (78), Expect = 0.16
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++ + V+ G A + G P P+ WY +EE G +HD
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY--------KEEQLLSTGFKCKFLHD 3244
Query: 107 SG--LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L + + D YTC A N YG + +L V
Sbjct: 3245 GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 34.3 bits (77), Expect = 0.21
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 74 PDPQFKWYNSIGKLLKEEEDEK---ERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNI 130
P+P WY S K+ + D+K E G +Q L I V+ D +YT VA N
Sbjct: 25220 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ------LTINSVTTDDDAEYTVVARNK 25273
Query: 131 YG 132
YG
Sbjct: 25274 YG 25275
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 6/93 (6%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMH-DSGLLNITK 114
+ VK G++ + V G P P+ W K+ D K DS ++TK
Sbjct: 11714 LTVKAGDTIRLEAGVRGKPFPEVAWTKD-----KDATDLTRSPRVKIDTRADSSKFSLTK 11768
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
SD GKY A+N G+ T+ V+ G
Sbjct: 11769 AKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11801
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 12/100 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D + ++ G+ +++ +V G P+P+ W +E D E K + +G
Sbjct: 22558 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKG-----DKELDLCE----KVSLQYTGKRATA 22608
Query: 114 KVSFSDR---GKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
+ F DR GKYT N GT +V ++V+ + G G
Sbjct: 22609 VIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCG 22648
Score = 33.5 bits (75), Expect = 0.36
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 6/103 (5%)
Query: 45 SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM 104
SV + + + ++VK G + + G+P P KW ++ +E E
Sbjct: 11012 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD------ 11065
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ S +L I D G+Y SN G+ V L V+ G
Sbjct: 11066 NFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPG 11108
Score = 33.5 bits (75), Expect = 0.36
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 6/94 (6%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D +I+K G S I V G P P+ W+ E EK + S L +
Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFKD------GVEIEKRMNMEITDVLGSTSLFVR 21522
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ RG YT A N G+ + ++V T G
Sbjct: 21523 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Score = 33.1 bits (74), Expect = 0.47
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R + V++G+ + V GIP P K+Y ++ + + + G D
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG------D 157
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I + D G Y+ A+N G +T L V
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 32.7 bits (73), Expect = 0.61
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 26/99 (26%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK- 114
I ++ G S + + G P P+ KW G++ D+ ++++T
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----------------RDAAIIDVTSS 16497
Query: 115 --------VSFSDRGKYTCVASNIYGTVNNTVTLRVIFT 145
V+ D GKYT N GT + VT+RV+ T
Sbjct: 16498 FTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16536
Score = 32.3 bits (72), Expect = 0.80
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + + V+G P P +W L+ +++ +E + + D L I
Sbjct: 17136 DTIVVNAGETFRLEADVHGKPLPTIEW-------LRGDKEIEESARCEIKNTDFKALLIV 17188
Query: 114 KVSFS-DRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
K + D G+Y ASN+ G+ + V ++V+ G
Sbjct: 17189 KDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPG 17223
Score = 32.0 bits (71), Expect = 1.0
Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 8/121 (6%)
Query: 25 LATAKSVTNSTLNGTNVVLG---SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWY 81
LA +T T + L P I R V +G+ A V G PDP+ +WY
Sbjct: 2007 LAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWY 2066
Query: 82 NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLR 141
+ K+ + +R W + L I V+ D A NI G ++ L
Sbjct: 2067 KNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLL 2121
Query: 142 V 142
V
Sbjct: 2122 V 2122
Score = 32.0 bits (71), Expect = 1.0
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD-SGLLNI 112
D I+V G S ++ +YG P P +W +K +++ + + D + L++
Sbjct: 16054 DTIVVHAGESFKVDADIYGKPIPTIQW-------IKGDQELSNTARLEIKSTDFATSLSV 16106
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G Y A N+ G + TV ++V+ G
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG 16141
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNS-IGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
+ ++ G S + SV G P P W I + D E LL + K
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE---------SYSLLIVDK 23009
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
V+ D GKYT A N G + TV ++V T G
Sbjct: 23010 VNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG 23042
Score = 32.0 bits (71), Expect = 1.0
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKE--EEDEKERGGGKWQMHDSGLLNITKV 115
V+ ++A + C V G P P KWY +++ + + +E GG Q L I V
Sbjct: 24442 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ------LIIASV 24495
Query: 116 SFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ D Y A+N G+V+ T +L V
Sbjct: 24496 TDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 31.6 bits (70), Expect = 1.4
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSF 117
++ G I V G P P W G+ LK+ + S +L+I + +
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVE-----ETATSTVLHIKEGNK 17879
Query: 118 SDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D GKYT A+N GT +++ V+ G
Sbjct: 17880 DDFGKYTVTATNSAGTATENLSVIVLEKPG 17909
Score = 31.6 bits (70), Expect = 1.4
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 8/95 (8%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNI 112
D I+VK G IN + G P P W K+ + +ER + D+ LL +
Sbjct: 19300 DVIVVKAGEVLKINADIAGRPLPVISW-------AKDGIEIEERARTEIISTDNHTLLTV 19352
Query: 113 TKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
D G+Y N+ GT + V +V+ G
Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPG 19387
Score = 31.6 bits (70), Expect = 1.4
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 15/101 (14%)
Query: 50 IARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGG-GKWQMHD-- 106
+A +I K G + G P P W +DEK G ++ + +
Sbjct: 20778 VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW----------RKDEKNLGSDARYSIENTD 20827
Query: 107 -SGLLNITKVSFSDRGKYTCVASNIYG-TVNNTVTLRVIFT 145
S LL I +V+ +D GKY N G ++TV+++V+ T
Sbjct: 20828 SSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 20868
Score = 31.2 bits (69), Expect = 1.8
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P ++V EG++A + G P P+ W+ G+++ G + D
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRD-GQVI----STSTLPGVQISFSD 60
Query: 107 S-GLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I V+ ++ G+Y+ A+N G +T L V
Sbjct: 61 GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 30.8 bits (68), Expect = 2.3
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
D I+V G + ++ + G P P W K KE E+ R K + + L+ +
Sbjct: 18218 DVIVVHAGETFVLEADIRGKPIPDVVW----SKDGKELEETAARMEIKSTIQKTTLV-VK 18272
Query: 114 KVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+D G+Y SN+ GT + +T++V+ G
Sbjct: 18273 DCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG 18306
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDS-GLLNITK 114
I V G + + G P P W+ + KL + E E H L I +
Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVET-------HTKVAKLTIRE 23303
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ D G+YT N+ GT + T+ + ++ G
Sbjct: 23304 TTIRDTGEYTLELKNVTGTTSETIKVIILDKPG 23336
Score = 30.8 bits (68), Expect = 2.3
Identities = 24/94 (25%), Positives = 34/94 (36%), Gaps = 6/94 (6%)
Query: 49 IIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSG 108
I+ + + V EG SA +C G P P W G++L +
Sbjct: 26066 ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK-GQVLSTSARHQVT-----TTKYKS 26119
Query: 109 LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
I+ V SD G Y+ V N G TL +
Sbjct: 26120 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Score = 30.4 bits (67), Expect = 3.0
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 8/78 (10%)
Query: 70 VYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASN 129
+ G P P+ KW G+ L + E LL + V+ D GKY N
Sbjct: 15387 IKGRPAPEVKWARDHGESLDKASIESTSS--------YTLLIVGNVNRFDSGKYILTVEN 15438
Query: 130 IYGTVNNTVTLRVIFTSG 147
G+ + V +RV+ T G
Sbjct: 15439 SSGSKSAFVNVRVLDTPG 15456
Score = 30.0 bits (66), Expect = 4.0
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 11/99 (11%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDE---KERGGGKWQ 103
PV + + EG +A + V G P P+ W++ +++ + + KE G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG----- 1465
Query: 104 MHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
+ L I + SD G++T VA N G + +V L V
Sbjct: 1466 ---TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 30.0 bits (66), Expect = 4.0
Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 10/93 (10%)
Query: 56 IIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGL-LNITK 114
+IVK G S + G P P W + D R DS L I
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLW---------SKPDTDLRTRAYVDTTDSRTSLTIEN 19749
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSG 147
+ +D GKYT N+ + T+ ++V+ T G
Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG 19782
Score = 28.9 bits (63), Expect = 8.8
Identities = 29/124 (23%), Positives = 48/124 (38%), Gaps = 24/124 (19%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEK-----ERGGGK 101
P +I RT + VK G+ ++ S+ G P P W ++ EE ++ R G+
Sbjct: 8184 PKVILRTS-LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGE 8242
Query: 102 WQMHDSGLLNIT-KVSFS-----------------DRGKYTCVASNIYGTVNNTVTLRVI 143
Q + +L +T ++S D G Y N +G T+ V+
Sbjct: 8243 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8302
Query: 144 FTSG 147
T G
Sbjct: 8303 DTPG 8306
Score = 28.9 bits (63), Expect = 8.8
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 110 LNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMG 150
L + + +D GKYT N G+ + T T++V+ T G G
Sbjct: 21916 LTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 21956
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 52.8 bits (125), Expect = 6e-07
Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 15/114 (13%)
Query: 32 TNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEE 91
T++ L+ TN+ PV R V +G +A++ C V G P P W K E
Sbjct: 469 THTYLDVTNIA----PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITW--------KRE 516
Query: 92 EDEKERGG---GKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G ++ + +SG L I V D G YTC A+N G++N + TL V
Sbjct: 517 NHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570
Score = 34.3 bits (77), Expect = 0.21
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 7/77 (9%)
Query: 66 INCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTC 125
I C G+P P +WY + + + ++++ SG L I K+ D G + C
Sbjct: 406 IGCQAMGVPLPTLQWYKDAISISRLQNP-------RYKVLASGGLRIQKLRPEDSGIFQC 458
Query: 126 VASNIYGTVNNTVTLRV 142
ASN G + L V
Sbjct: 459 FASNEGGEIQTHTYLDV 475
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 272
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 273 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 84
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 132
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 123 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 181
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 182 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 208
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 449
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 450 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 496
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 272
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 273 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 84
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 132
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 123 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 181
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 182 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 208
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 449
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 450 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 496
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R ++ V +SA C G P P +W G+L K ++++ D
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS----------RYEIRD 311
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
L I KV+ D G YTCVA N+ G + TL V
Sbjct: 312 DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P I+ +IV +G A +NC G P P +WY ++ +++D + +
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR----MLLP 123
Query: 107 SGLLNITKV-----SFSDRGKYTCVASNIYG-TVNNTVTLRVIFTSGD 148
SG L ++ S D G Y CVA N G V++ +L V D
Sbjct: 124 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 171
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 45 SVPVIIARTDH------IIVKEGNSALINCSV-YGIPDPQFKWYNSIGKLLKEEEDEKER 97
S+ V I R D ++V G A++ C G P+P W G L ++++
Sbjct: 162 SLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKD-GSPLDDKDERITI 220
Query: 98 GGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
GGK L IT SD GKY CV +N+ G
Sbjct: 221 RGGK--------LMITYTRKSDAGKYVCVGTNMVG 247
Score = 36.6 bits (83), Expect = 0.042
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 21 LVSTLATAKSV-TNSTLNGTNVVLGSVPVIIAR--TDHIIVKEGNSALINCSVYGIPDPQ 77
+ TL A S+ T + L T+V+ P +I + + + +G L +C G P P
Sbjct: 427 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPT 485
Query: 78 FKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYG 132
W G L+ ++ + + ++G+L I D G+YTC+AS G
Sbjct: 486 ILWRKD-GVLVSTQDS-------RIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 532
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/108 (32%), Positives = 53/108 (49%), Gaps = 13/108 (12%)
Query: 45 SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEE----DEKERGGG 100
+ PV + + V++G +C V G P P +W+ GKLL+E++ +E ++GG
Sbjct: 5124 AAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKD-GKLLEEDDHYMINEDQQGGH 5182
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGD 148
+ L IT V +D G Y C+A N G + LRV TS D
Sbjct: 5183 Q--------LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTD 5222
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R +V G A ++C + G P PQ W E++ + G ++++
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW---------EKDQQPVAAGARFRLAQ 60
Query: 107 SG---LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G L I ++ D G+Y C A N G V L+V
Sbjct: 61 DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLN-ITKVS 116
V EG A ++C V G P P+ W G+L+ E G + +++ N + K+
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKD-GQLVTE--------GRRHVVYEDAQENFVLKIL 299
Query: 117 F---SDRGKYTCVASNIYGTVNNTVTLRV 142
F SDRG YTC ASN+ G ++V + V
Sbjct: 300 FCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 60 EGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD---SGL--LNITK 114
EG A C++ G P PQ +WY G LL G K+Q SGL L I
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKD-GALLTT--------GNKFQTLSEPRSGLLVLVIRA 6171
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRV 142
S D G Y C N G+ + LR+
Sbjct: 6172 ASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 35.0 bits (79), Expect = 0.12
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 4/102 (3%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R I V+EG+ A C V G P P W + G+ L E + + R ++ +
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW-SKDGRRLGEPDGPRVR---VEELGE 165
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGD 148
+ L I D G Y A N G + L V + D
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207
Score = 32.0 bits (71), Expect = 1.0
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 26/98 (26%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG-------------GGKWQM 104
VK+G+S + V G P P W +E ERG Q
Sbjct: 5382 VKKGSSITFSVKVEGRPVPTVHWLR----------EEAERGVLWIGPDTPGYTVASSAQQ 5431
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
H LL++ + +G YTC+ASN G + +L V
Sbjct: 5432 HSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHV 5466
Score = 31.6 bits (70), Expect = 1.4
Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 12/136 (8%)
Query: 19 LILVSTLATAKSVTNSTL----NGTNVVLGSVPVIIART-DHIIVKEGNSALINCSVYGI 73
L+L T +T + T+ + +V+ +PV++ R + +E S +++C
Sbjct: 2436 LMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPA 2495
Query: 74 PDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGT 133
P +WY L E+ + G QM + L I ++ +D G Y C A + + +
Sbjct: 2496 PKA-VQWYKDDTPLSPSEKFKMSLEG---QMAE---LRILRLMPADAGVYRCQAGSAHSS 2548
Query: 134 VNNTVTLRVIFTSGDM 149
TV R + +G +
Sbjct: 2549 TEVTVEAREVTVTGPL 2564
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/108 (32%), Positives = 53/108 (49%), Gaps = 13/108 (12%)
Query: 45 SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEE----DEKERGGG 100
+ PV + + V++G +C V G P P +W+ GKLL+E++ +E ++GG
Sbjct: 5124 AAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKD-GKLLEEDDHYMINEDQQGGH 5182
Query: 101 KWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGD 148
+ L IT V +D G Y C+A N G + LRV TS D
Sbjct: 5183 Q--------LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTD 5222
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R +V G A ++C + G P PQ W E++ + G ++++
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW---------EKDQQPVAAGARFRLAQ 60
Query: 107 SG---LLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
G L I ++ D G+Y C A N G V L+V
Sbjct: 61 DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLN-ITKVS 116
V EG A ++C V G P P+ W G+L+ E G + +++ N + K+
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKD-GQLVTE--------GRRHVVYEDAQENFVLKIL 299
Query: 117 F---SDRGKYTCVASNIYGTVNNTVTLRV 142
F SDRG YTC ASN+ G ++V + V
Sbjct: 300 FCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 37.7 bits (86), Expect = 0.019
Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 60 EGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD---SGL--LNITK 114
EG A C++ G P PQ +WY G LL G K+Q SGL L I
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKD-GALLTT--------GNKFQTLSEPRSGLLVLVIRA 6171
Query: 115 VSFSDRGKYTCVASNIYGTVNNTVTLRV 142
S D G Y C N G+ + LR+
Sbjct: 6172 ASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 35.0 bits (79), Expect = 0.12
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 4/102 (3%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + R I V+EG+ A C V G P P W + G+ L E + + R ++ +
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSW-SKDGRRLGEPDGPRVR---VEELGE 165
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGD 148
+ L I D G Y A N G + L V + D
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD 207
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + + + + G +A + G P P WY +L+ +++ G +
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS--- 6413
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTV 134
L + V+ D G YTC+A N G V
Sbjct: 6414 ---LVLRHVASKDAGVYTCLAQNTGGQV 6438
Score = 33.9 bits (76), Expect = 0.27
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 5/95 (5%)
Query: 47 PVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHD 106
P + V G S + C V P Q W L + R + +
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPL-----ESSSRVLISATLKN 7517
Query: 107 SGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLR 141
LL I V D G YTC SN GTV T LR
Sbjct: 7518 FQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 7552
Score = 32.0 bits (71), Expect = 1.0
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 26/98 (26%)
Query: 58 VKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERG-------------GGKWQM 104
VK+G+S + V G P P W +E ERG Q
Sbjct: 5382 VKKGSSITFSVKVEGRPVPTVHWLR----------EEAERGVLWIGPDTPGYTVASSAQQ 5431
Query: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRV 142
H LL++ + +G YTC+ASN G + +L V
Sbjct: 5432 HSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHV 5466
Score = 31.6 bits (70), Expect = 1.4
Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 12/136 (8%)
Query: 19 LILVSTLATAKSVTNSTL----NGTNVVLGSVPVIIART-DHIIVKEGNSALINCSVYGI 73
L+L T +T + T+ + +V+ +PV++ R + +E S +++C
Sbjct: 2436 LMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPA 2495
Query: 74 PDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGT 133
P +WY L E+ + G QM + L I ++ +D G Y C A + + +
Sbjct: 2496 PKA-VQWYKDDTPLSPSEKFKMSLEG---QMAE---LRILRLMPADAGVYRCQAGSAHSS 2548
Query: 134 VNNTVTLRVIFTSGDM 149
TV R + +G +
Sbjct: 2549 TEVTVEAREVTVTGPL 2564
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 51.6 bits (122), Expect = 1e-06
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 10/82 (12%)
Query: 62 NSALINCSVYGIPDPQFKWY-NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
N ++C +G P P +W+ N G L GG + ++++G L I + D+
Sbjct: 457 NRTRLDCPFFGSPIPTLRWFKNGQGSNLD---------GGNYHVYENGSLEIKMIRKEDQ 507
Query: 121 GKYTCVASNIYGTVNNTVTLRV 142
G YTCVA+NI G N V L V
Sbjct: 508 GIYTCVATNILGKAENQVRLEV 529
Score = 51.2 bits (121), Expect = 2e-06
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+V G L+ C G+P P WY G L ++ K++ + L IT VS
Sbjct: 268 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK--------AKFENFNKAL-RITNVS 318
Query: 117 FSDRGKYTCVASNIYGTVNNTVTLRV 142
D G+Y C+ASN G++ +T+++RV
Sbjct: 319 EEDSGEYFCLASNKMGSIRHTISVRV 344
Score = 29.3 bits (64), Expect = 6.7
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 12/94 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
DHI+ N LI C G P P F W + + +D + SG L I
Sbjct: 44 DHIVDPRDN-ILIECEAKGNPAPSFHWTRN-SRFFNIAKDPRVS-----MRRRSGTLVID 96
Query: 114 KVSFSD----RGKYTCVASNIYGT-VNNTVTLRV 142
S G+Y C A N +GT ++N + L+V
Sbjct: 97 FRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV 130
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 51.6 bits (122), Expect = 1e-06
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 10/82 (12%)
Query: 62 NSALINCSVYGIPDPQFKWY-NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
N ++C +G P P +W+ N G L GG + ++++G L I + D+
Sbjct: 457 NRTRLDCPFFGSPIPTLRWFKNGQGSNLD---------GGNYHVYENGSLEIKMIRKEDQ 507
Query: 121 GKYTCVASNIYGTVNNTVTLRV 142
G YTCVA+NI G N V L V
Sbjct: 508 GIYTCVATNILGKAENQVRLEV 529
Score = 51.2 bits (121), Expect = 2e-06
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+V G L+ C G+P P WY G L ++ K++ + L IT VS
Sbjct: 268 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK--------AKFENFNKAL-RITNVS 318
Query: 117 FSDRGKYTCVASNIYGTVNNTVTLRV 142
D G+Y C+ASN G++ +T+++RV
Sbjct: 319 EEDSGEYFCLASNKMGSIRHTISVRV 344
Score = 29.3 bits (64), Expect = 6.7
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 12/94 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
DHI+ N LI C G P P F W + + +D + SG L I
Sbjct: 44 DHIVDPRDN-ILIECEAKGNPAPSFHWTRN-SRFFNIAKDPRVS-----MRRRSGTLVID 96
Query: 114 KVSFSD----RGKYTCVASNIYGT-VNNTVTLRV 142
S G+Y C A N +GT ++N + L+V
Sbjct: 97 FRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV 130
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 51.6 bits (122), Expect = 1e-06
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 10/82 (12%)
Query: 62 NSALINCSVYGIPDPQFKWY-NSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDR 120
N ++C +G P P +W+ N G L GG + ++++G L I + D+
Sbjct: 457 NRTRLDCPFFGSPIPTLRWFKNGQGSNLD---------GGNYHVYENGSLEIKMIRKEDQ 507
Query: 121 GKYTCVASNIYGTVNNTVTLRV 142
G YTCVA+NI G N V L V
Sbjct: 508 GIYTCVATNILGKAENQVRLEV 529
Score = 51.2 bits (121), Expect = 2e-06
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 57 IVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVS 116
+V G L+ C G+P P WY G L ++ K++ + L IT VS
Sbjct: 268 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK--------AKFENFNKAL-RITNVS 318
Query: 117 FSDRGKYTCVASNIYGTVNNTVTLRV 142
D G+Y C+ASN G++ +T+++RV
Sbjct: 319 EEDSGEYFCLASNKMGSIRHTISVRV 344
Score = 29.3 bits (64), Expect = 6.7
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 12/94 (12%)
Query: 54 DHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNIT 113
DHI+ N LI C G P P F W + + +D + SG L I
Sbjct: 44 DHIVDPRDN-ILIECEAKGNPAPSFHWTRN-SRFFNIAKDPRVS-----MRRRSGTLVID 96
Query: 114 KVSFSD----RGKYTCVASNIYGT-VNNTVTLRV 142
S G+Y C A N +GT ++N + L+V
Sbjct: 97 FRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV 130
>gi|55956790 neurotrophic tyrosine kinase, receptor, type 2 isoform
b precursor [Homo sapiens]
Length = 477
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
++ V+EG S ++CSV G P P W +G L+ + +E H G L IT
Sbjct: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETS--------HTQGSLRITN 254
Query: 115 VSFSDRGK-YTCVASNIYGTVNNTVTLRVIF 144
+S D GK +CVA N+ G ++V L V F
Sbjct: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
>gi|65506779 neurotrophic tyrosine kinase, receptor, type 2 isoform
e precursor [Homo sapiens]
Length = 537
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
++ V+EG S ++CSV G P P W +G L+ + +E H G L IT
Sbjct: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETS--------HTQGSLRITN 254
Query: 115 VSFSDRGK-YTCVASNIYGTVNNTVTLRVIF 144
+S D GK +CVA N+ G ++V L V F
Sbjct: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
>gi|65506769 neurotrophic tyrosine kinase, receptor, type 2 isoform
d precursor [Homo sapiens]
Length = 553
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Query: 55 HIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITK 114
++ V+EG S ++CSV G P P W +G L+ + +E H G L IT
Sbjct: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETS--------HTQGSLRITN 254
Query: 115 VSFSDRGK-YTCVASNIYGTVNNTVTLRVIF 144
+S D GK +CVA N+ G ++V L V F
Sbjct: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,384,850
Number of Sequences: 37866
Number of extensions: 695494
Number of successful extensions: 4501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 2656
Number of HSP's gapped (non-prelim): 1525
length of query: 409
length of database: 18,247,518
effective HSP length: 105
effective length of query: 304
effective length of database: 14,271,588
effective search space: 4338562752
effective search space used: 4338562752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.