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Search of human proteins with 153791216
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791216 proteasome beta 11 subunit [Homo sapiens]
(300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791216 proteasome beta 11 subunit [Homo sapiens] 624 e-179
gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Hom... 244 5e-65
gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens] 238 6e-63
gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo... 233 1e-61
gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens] 176 3e-44
gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens] 133 2e-31
gi|23110925 proteasome beta 6 subunit [Homo sapiens] 102 3e-22
gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens] 89 5e-18
gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ... 86 5e-17
gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo... 85 7e-17
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens] 76 3e-14
gi|4506193 proteasome beta 1 subunit [Homo sapiens] 51 1e-06
gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 47 2e-05
gi|22538465 proteasome beta 3 subunit [Homo sapiens] 41 0.001
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 34 0.14
gi|22538467 proteasome beta 4 subunit [Homo sapiens] 33 0.23
gi|92859670 solute carrier family 6 (neurotransmitter transporte... 31 1.2
gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens] 31 1.5
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 31 1.5
gi|7657013 apoptosis antagonizing transcription factor [Homo sap... 30 3.4
gi|7662162 ALEX2 protein [Homo sapiens] 30 3.4
gi|29540562 ALEX2 protein [Homo sapiens] 30 3.4
gi|109633022 mucosal vascular addressin cell adhesion molecule 1... 29 5.8
gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo sap... 28 7.6
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 28 7.6
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 28 7.6
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 28 9.9
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 28 9.9
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 28 9.9
>gi|153791216 proteasome beta 11 subunit [Homo sapiens]
Length = 300
Score = 624 bits (1609), Expect = e-179
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHG 60
MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHG
Sbjct: 1 MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHG 60
Query: 61 VIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREG 120
VIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREG
Sbjct: 61 VIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREG 120
Query: 121 QLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSG 180
QLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSG
Sbjct: 121 QLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSG 180
Query: 181 SPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSD 240
SPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSD
Sbjct: 181 SPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSD 240
Query: 241 ACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV 300
ACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV
Sbjct: 241 ACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV 300
>gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Homo
sapiens]
Length = 276
Score = 244 bits (624), Expect = 5e-65
Identities = 130/265 (49%), Positives = 171/265 (64%), Gaps = 27/265 (10%)
Query: 1 MALQDVCKWQSPDTQGPSPHLPRAGGW-----------------AVPRGCDPQTFLQIHG 43
MAL DVC +P Q P LP AG A+PRG P F Q G
Sbjct: 1 MALLDVCG--APRGQRPESALPVAGSGRRSDPGHYSFSMRSPELALPRGMQPTEFFQSLG 58
Query: 44 P--------RLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTS 95
+AHGTTTLAF+F+HGVIAA D+R+S GSY++ KVI ++ +LLGT S
Sbjct: 59 GDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMS 118
Query: 96 GTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDR 155
G +ADC W R+L +E RL LR G+ SV++A+KLLS MM QYRG+ L + + +CGWD+
Sbjct: 119 GCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDK 178
Query: 156 SGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHR 215
GP L+YV GTRL G++FS GSG+ YAYGV+D GYR ++S +EAY L R A+A+ATHR
Sbjct: 179 KGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHR 238
Query: 216 DAYSGGSVDLFHVRESGWEHVSRSD 240
D+YSGG V+++H++E GW V +D
Sbjct: 239 DSYSGGVVNMYHMKEDGWVKVESTD 263
>gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]
Length = 263
Score = 238 bits (606), Expect = 6e-63
Identities = 117/222 (52%), Positives = 158/222 (71%), Gaps = 9/222 (4%)
Query: 24 AGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKV 83
A GW VP +P G + HGTTTLAF+FRHGVI AAD+R++ G+Y+A KV
Sbjct: 43 APGWGVPE--EP-------GIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKV 93
Query: 84 IPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLD 143
I ++ +LLGT +G +ADC+ W R+L R+ R+ ELR + SVA+A+KLL+ M+ QY+G+
Sbjct: 94 IEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMG 153
Query: 144 LCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYA 203
L + T +CGWD+ GP L+YV S+G R+ G FSVGSGS YAYGV+DRGY YD+ ++AY
Sbjct: 154 LSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYD 213
Query: 204 LARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLY 245
LAR A+ AT+RDAYSGG+V+L+HVRE GW VS + L+
Sbjct: 214 LARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLH 255
>gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo
sapiens]
Length = 272
Score = 233 bits (595), Expect = 1e-61
Identities = 114/217 (52%), Positives = 154/217 (70%), Gaps = 8/217 (3%)
Query: 32 GCDPQTFLQIHGP--------RLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKV 83
G +P F Q G +AHGTTTLAF+F+HGVIAA D+R+S GSY++ KV
Sbjct: 43 GLEPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKV 102
Query: 84 IPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLD 143
I ++ +LLGT SG +ADC W R+L +E RL LR G+ SV++A+KLLS MM QYRG+
Sbjct: 103 IEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMG 162
Query: 144 LCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYA 203
L + + +CGWD+ GP L+YV GTRL G++FS GSG+ YAYGV+D GYR ++S +EAY
Sbjct: 163 LSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYD 222
Query: 204 LARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSD 240
L R A+A+ATHRD+YSGG V+++H++E GW V +D
Sbjct: 223 LGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTD 259
>gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]
Length = 160
Score = 176 bits (445), Expect = 3e-44
Identities = 82/151 (54%), Positives = 112/151 (74%)
Query: 95 SGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWD 154
+G +ADC+ W R+L R+ R+ ELR + SVA+A+KLL+ M+ QY+G+ L + T +CGWD
Sbjct: 2 AGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD 61
Query: 155 RSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATH 214
+ GP L+YV S+G R+ G FSVGSGS YAYGV+DRGY YD+ ++AY LAR A+ AT+
Sbjct: 62 KRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATY 121
Query: 215 RDAYSGGSVDLFHVRESGWEHVSRSDACVLY 245
RDAYSGG+V+L+HVRE GW VS + L+
Sbjct: 122 RDAYSGGAVNLYHVREDGWIRVSSDNVADLH 152
>gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]
Length = 203
Score = 133 bits (334), Expect = 2e-31
Identities = 66/135 (48%), Positives = 93/135 (68%), Gaps = 9/135 (6%)
Query: 24 AGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKV 83
A GW VP +P G + HGTTTLAF+FRHGVI AAD+R++ G+Y+A KV
Sbjct: 43 APGWGVPE--EP-------GIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKV 93
Query: 84 IPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLD 143
I ++ +LLGT +G +ADC+ W R+L R+ R+ ELR + SVA+A+KLL+ M+ QY+G+
Sbjct: 94 IEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMG 153
Query: 144 LCVATALCGWDRSGP 158
L + T +CGWD+ GP
Sbjct: 154 LSMGTMICGWDKRGP 168
>gi|23110925 proteasome beta 6 subunit [Homo sapiens]
Length = 239
Score = 102 bits (255), Expect = 3e-22
Identities = 63/187 (33%), Positives = 95/187 (50%), Gaps = 2/187 (1%)
Query: 49 GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108
GTT +A +F GV+ AD+R++ GSY+A + K+ P+H + SG++AD +
Sbjct: 34 GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAV 93
Query: 109 QRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWD-RSGPELFYVYSDG 167
+L + + P V +AA L M +YR DL + GWD + G +++ V G
Sbjct: 94 TYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSVPMGG 152
Query: 168 TRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFH 227
++ GSGS Y YG +D YR M+ +E A+A A RD SGG + L
Sbjct: 153 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAA 212
Query: 228 VRESGWE 234
+ ESG E
Sbjct: 213 IAESGVE 219
>gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]
Length = 277
Score = 89.0 bits (219), Expect = 5e-18
Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 1/177 (0%)
Query: 49 GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108
GTT ++ G++ ADTR++ G VA K+ + ++ +GT+AD +++
Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102
Query: 109 QRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGT 168
L L L G+LP V +A ++L M+ +Y+G + A L G D +GP L+ +Y G+
Sbjct: 103 SSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDVTGPHLYSIYPHGS 161
Query: 169 RLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDL 225
+ ++GSGS A V + +R DM +EA L A+A D SG ++DL
Sbjct: 162 TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218
>gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo
sapiens]
Length = 219
Score = 85.5 bits (210), Expect = 5e-17
Identities = 66/221 (29%), Positives = 103/221 (46%), Gaps = 24/221 (10%)
Query: 17 PSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVA 76
P+ LPRAG ++H GTT +A F GV+ +D+R S G V
Sbjct: 7 PTGDLPRAG--------------EVHT-----GTTIMAVEFDGGVVMGSDSRVSAGEAVV 47
Query: 77 CPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMM 136
K+ P+H+ + SG++AD + +L L + + P V +AA ++ +
Sbjct: 48 NRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNIS 107
Query: 137 SQYRGLDLCVATALCGWD-RSGPELFYVYSDGTRLQGDIFSV-GSGSPYAYGVLDRGYRY 194
+YR DL + GWD R G +++ G L F++ GSGS + YG +D Y+
Sbjct: 108 YKYRE-DLSAHLMVAGWDQREGGQVYGTL--GGMLTRQPFAIGGSGSTFIYGYVDAAYKP 164
Query: 195 DMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEH 235
MS +E A+A A RD SGG + L + +G +H
Sbjct: 165 GMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDH 205
>gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo
sapiens]
Length = 209
Score = 85.1 bits (209), Expect = 7e-17
Identities = 59/189 (31%), Positives = 93/189 (49%), Gaps = 5/189 (2%)
Query: 49 GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108
GTT +A F GV+ +D+R S G V K+ P+H+ + SG++AD +
Sbjct: 10 GTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMA 69
Query: 109 QRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWD-RSGPELFYVYSDG 167
+L L + + P V +AA ++ + +YR DL + GWD R G +++ G
Sbjct: 70 AYQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGTL--G 126
Query: 168 TRLQGDIFSV-GSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLF 226
L F++ GSGS + YG +D Y+ MS +E A+A A RD SGG + L
Sbjct: 127 GMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLV 186
Query: 227 HVRESGWEH 235
+ +G +H
Sbjct: 187 TITAAGVDH 195
>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
Length = 273
Score = 76.3 bits (186), Expect = 3e-14
Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 8/220 (3%)
Query: 19 PHLPRAGGWAVPRGCDPQTFLQ--IHGPRLAH----GTTTLAFRFRHGVIAAADTRSSCG 72
P L GG++ C L+ + G ++ H GTT F+ GVI ADTR++
Sbjct: 4 PALEPRGGFSF-ENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATND 62
Query: 73 SYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLL 132
S VA + K+ + + +G +AD R++ ++ L L G+ P VA+ ++L
Sbjct: 63 SVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRIL 122
Query: 133 SAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGY 192
+ +Y+G + + + G D +GP+L+ V+ G+ + ++GSG A VL+ +
Sbjct: 123 RQTLFRYQG-HVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRF 181
Query: 193 RYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESG 232
+ +M+ + A L AV D SGG+VD + ++G
Sbjct: 182 QPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTG 221
>gi|4506193 proteasome beta 1 subunit [Homo sapiens]
Length = 241
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 10/199 (5%)
Query: 44 PRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCAT 103
P + +G T LA I A+DTR S G + S K + + SG DC T
Sbjct: 32 PYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLT 91
Query: 104 WYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYV 163
++++ L++ + + + + A +LS ++ R V + G D G Y
Sbjct: 92 LTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYS 151
Query: 164 YSDGTRLQGDIFSV-GSGSPYAYGVLDR--GYR-------YDMSTQEAYALARCAVAHAT 213
+ Q D F GS S +LD G++ +S A L + A
Sbjct: 152 FDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAA 211
Query: 214 HRDAYSGGSVDLFHVRESG 232
RD Y+G ++ + V + G
Sbjct: 212 ERDVYTGDALRICIVTKEG 230
>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
Length = 241
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 12/163 (7%)
Query: 49 GTTTLAFRFRHGVIAAADTRSSCGSYVACPASC-KVIPVHQHLLGTTSGTSADCATWYRV 107
G+T + + GV A + R + S + P+S K++ + H+ SG AD T
Sbjct: 34 GSTAIGIQTSEGVCLAVEKRIT--SPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDK 91
Query: 108 LQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLD---------LCVATALCGWDRSGP 158
+ E + + +V S + +S + Q+ D VA G D GP
Sbjct: 92 ARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGP 151
Query: 159 ELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEA 201
+LF++ GT +Q D ++GS S A L Y M+ +EA
Sbjct: 152 QLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEA 194
>gi|22538465 proteasome beta 3 subunit [Homo sapiens]
Length = 205
Score = 40.8 bits (94), Expect = 0.001
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 4/186 (2%)
Query: 48 HGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRV 107
+G +A + ++ V AAD R + + K+ P+ L +G + D T +
Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66
Query: 108 LQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSD- 166
L+ L L EL+EG+ + +++ ++ + R + G D + F D
Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126
Query: 167 -GTRLQGDIFSV-GSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVD 224
G + D F V G+ + YG+ + + +M + A+ +A RDA SG V
Sbjct: 127 IGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGV- 185
Query: 225 LFHVRE 230
+ H+ E
Sbjct: 186 IVHIIE 191
>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
Length = 234
Score = 34.3 bits (77), Expect = 0.14
Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 13/164 (7%)
Query: 46 LAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWY 105
+A G ++ + +GV+ A + + Y KV P+ +H+ SG D Y
Sbjct: 29 VAGGAPSVGIKAANGVVLATEKKQKSILYDERSVH-KVEPITKHIGLVYSGMGPD----Y 83
Query: 106 RVL-QRELRLRE----LREGQLPSVASAAKLLSAMM--SQYRGL-DLCVATALCGWDRSG 157
RVL R +L + + + +P+ ++ S M +Q G+ V+ +CGW+
Sbjct: 84 RVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGR 143
Query: 158 PELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEA 201
P LF G ++G L++ Y D+ ++A
Sbjct: 144 PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDA 187
>gi|22538467 proteasome beta 4 subunit [Homo sapiens]
Length = 264
Score = 33.5 bits (75), Expect = 0.23
Identities = 51/191 (26%), Positives = 75/191 (39%), Gaps = 5/191 (2%)
Query: 49 GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108
GT+ L +F GV+ AAD S GS +++ V+ + SG AD +VL
Sbjct: 53 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVL 112
Query: 109 -QRELRLRELREGQLPSV-ASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPE-LFYVYS 165
Q + L +G S A + L AM S+ ++ T + G G L YV
Sbjct: 113 GQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDM 172
Query: 166 DGTRLQGDIFSVGSGSPYAYGVLDRGYRYD--MSTQEAYALARCAVAHATHRDAYSGGSV 223
G + + G G+ A +L +S EA L + +RDA S
Sbjct: 173 LGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRF 232
Query: 224 DLFHVRESGWE 234
+ V E G E
Sbjct: 233 QIATVTEKGVE 243
>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
glycine), member 5 [Homo sapiens]
Length = 797
Score = 31.2 bits (69), Expect = 1.2
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 242 CVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTET 299
C E+ KL PE A+ HP+ A R + ++EL P P R+P T
Sbjct: 3 CSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQEL---PAAAAPPPPRVPRSAST 57
>gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens]
Length = 358
Score = 30.8 bits (68), Expect = 1.5
Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 10/53 (18%)
Query: 253 EPEPEEDASHAHPEPATAHRAAEDRELSVG----------PGEVTPGDSRMPA 295
+P P SH HP P AH AA + + PG TP + +P+
Sbjct: 182 QPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPS 234
>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
Length = 800
Score = 30.8 bits (68), Expect = 1.5
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 19/94 (20%)
Query: 9 WQSPDTQGPSPHLPRAGGWAVP----RGCDPQTFLQIHGPRLAHGTTTLAFRF------- 57
W P + P+P L GG +P RG P+T ++ GP+ + G +L+ F
Sbjct: 391 WPPPSLRTPTPGLTEGGGTGLPSKQRRGPSPKT--ELGGPQGSLGRASLSGPFGPGPQGG 448
Query: 58 ------RHGVIAAADTRSSCGSYVACPASCKVIP 85
RH + R GS + PA ++ P
Sbjct: 449 PPSRDRRHLGVQIGRVRVPLGSALPYPARSELAP 482
>gi|7657013 apoptosis antagonizing transcription factor [Homo
sapiens]
Length = 560
Score = 29.6 bits (65), Expect = 3.4
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 244 LYVELQKLLEPEPEEDASHAHPEPATAHRAAE 275
L ++L++LL P P E A PE ATA R +
Sbjct: 7 LALQLEQLLNPRPSEADPEADPEEATAARVID 38
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/133 (24%), Positives = 49/133 (36%), Gaps = 16/133 (12%)
Query: 175 FSVGSGSPYAYGVLDRGYRYDMSTQEAYAL----ARCAVAHATHRDAYSGGSVDLFHVRE 230
F++ GS ++ R D + EA AL A A+ +A SG +E
Sbjct: 61 FTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQ---AQE 117
Query: 231 SGWEHVSRSDACVLYVELQKLLEPEP---------EEDASHAHPEPATAHRAAEDRELSV 281
+ V V+ + + P P E A P+ A A R AE +V
Sbjct: 118 ADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAV 177
Query: 282 GPGEVTPGDSRMP 294
PG V P ++ P
Sbjct: 178 PPGTVVPTEAAAP 190
>gi|29540562 ALEX2 protein [Homo sapiens]
Length = 632
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/133 (24%), Positives = 49/133 (36%), Gaps = 16/133 (12%)
Query: 175 FSVGSGSPYAYGVLDRGYRYDMSTQEAYAL----ARCAVAHATHRDAYSGGSVDLFHVRE 230
F++ GS ++ R D + EA AL A A+ +A SG +E
Sbjct: 61 FTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQ---AQE 117
Query: 231 SGWEHVSRSDACVLYVELQKLLEPEP---------EEDASHAHPEPATAHRAAEDRELSV 281
+ V V+ + + P P E A P+ A A R AE +V
Sbjct: 118 ADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAV 177
Query: 282 GPGEVTPGDSRMP 294
PG V P ++ P
Sbjct: 178 PPGTVVPTEAAAP 190
>gi|109633022 mucosal vascular addressin cell adhesion molecule 1
isoform a precursor [Homo sapiens]
Length = 382
Score = 28.9 bits (63), Expect = 5.8
Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 253 EPEPEEDASHAHPEP-ATAHRAAEDRELSVGPGEVTPGDSRMPAGTE 298
EP P++ ++H P +T R E + GEV P S PAG +
Sbjct: 271 EPAPQQGSTHTPRSPGSTRTRRPEISQAGPTQGEVIPTGSSKPAGDQ 317
>gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo
sapiens]
Length = 328
Score = 28.5 bits (62), Expect = 7.6
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 7/60 (11%)
Query: 110 RELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTR 169
R LRLR R G A+AA +++ S+ C T++CG + P+L DGT+
Sbjct: 260 RRLRLRRPR-GPPGGAAAAASVMAPRRSR------CFCTSICGGRGARPQLPRTCGDGTQ 312
>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 1063
Score = 28.5 bits (62), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 231 SGWEHVSRSDACVLYVELQKLLEPE 255
SGW SD +Y+ELQ L++P+
Sbjct: 969 SGWAQAPLSDTAQVYMELQGLVDPQ 993
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 28.5 bits (62), Expect = 7.6
Identities = 16/39 (41%), Positives = 19/39 (48%)
Query: 92 GTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAK 130
G S S DC +RV +R E R G LP V AA+
Sbjct: 860 GPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAE 898
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 28.1 bits (61), Expect = 9.9
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 6/37 (16%)
Query: 260 ASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAG 296
+SH H H +AE+R L + G+ +PG+ R P G
Sbjct: 117 SSHGH-----LHDSAEERRL-IAEGDASPGEDRTPPG 147
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 28.1 bits (61), Expect = 9.9
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 6/85 (7%)
Query: 3 LQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFL---QIHGPRLAHGTTTLAFRFRH 59
+Q C+ SP T GP P W C L + R H T A R R
Sbjct: 58 VQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRT 117
Query: 60 GVIAAADTRSSCGSYVACPASCKVI 84
G A A C + +CP VI
Sbjct: 118 GFFAHA---GFCLEHASCPPGAGVI 139
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 28.1 bits (61), Expect = 9.9
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 6/85 (7%)
Query: 3 LQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFL---QIHGPRLAHGTTTLAFRFRH 59
+Q C+ SP T GP P W C L + R H T A R R
Sbjct: 58 VQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRT 117
Query: 60 GVIAAADTRSSCGSYVACPASCKVI 84
G A A C + +CP VI
Sbjct: 118 GFFAHA---GFCLEHASCPPGAGVI 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,466,170
Number of Sequences: 37866
Number of extensions: 651429
Number of successful extensions: 1881
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1854
Number of HSP's gapped (non-prelim): 30
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.