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Search of human proteins with 15147246
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15147246 guanine nucleotide binding protein (G protein),
gamma 8 [Homo sapiens]
(70 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15147246 guanine nucleotide binding protein (G protein), gamm... 140 3e-34
gi|54114974 guanine nucleotide binding protein (G protein), gamm... 109 4e-25
gi|148922937 guanine nucleotide binding protein (G protein), gam... 98 1e-21
gi|148922892 guanine nucleotide binding protein (G protein), gam... 98 1e-21
gi|4758450 guanine nucleotide binding protein (G protein), gamma... 98 1e-21
gi|6912394 guanine nucleotide binding protein (G protein), gamma... 91 2e-19
gi|32698769 guanine nucleotide binding protein (G protein), gamm... 81 2e-16
gi|51036603 G-protein gamma-12 subunit [Homo sapiens] 80 3e-16
gi|4885287 guanine nucleotide binding protein (G protein), gamma... 62 1e-10
gi|63055067 guanine nucleotide binding protein (G protein), gamm... 62 1e-10
gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens] 56 7e-09
gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens] 56 7e-09
gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens] 56 7e-09
gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo ... 52 1e-07
gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo ... 52 1e-07
gi|11386179 guanine nucleotide binding protein (G protein), gamm... 48 1e-06
gi|4758448 guanine nucleotide binding protein gamma 11 precursor... 46 6e-06
gi|14589849 guanine nucleotide binding protein-gamma transducing... 45 1e-05
gi|21361097 DNAJC25-GNG10 protein [Homo sapiens] 45 1e-05
gi|31742476 regulator of G-protein signalling 6 [Homo sapiens] 34 0.028
gi|7706567 guanine nucleotide binding protein (G protein), gamma... 33 0.048
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens] 31 0.18
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 29 0.70
gi|33624861 spectrin repeat containing, nuclear envelope 2 isofo... 29 0.70
gi|221307502 WEE1 tyrosine kinase isoform 2 [Homo sapiens] 27 4.5
gi|4507917 WEE1 tyrosine kinase isoform 1 [Homo sapiens] 27 4.5
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 26 5.9
gi|33624873 spectrin repeat containing, nuclear envelope 2 isofo... 26 5.9
>gi|15147246 guanine nucleotide binding protein (G protein), gamma
8 [Homo sapiens]
Length = 70
Score = 140 bits (352), Expect = 3e-34
Identities = 70/70 (100%), Positives = 70/70 (100%)
Query: 1 MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60
MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF
Sbjct: 1 MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60
Query: 61 RDKRLFCVLL 70
RDKRLFCVLL
Sbjct: 61 RDKRLFCVLL 70
>gi|54114974 guanine nucleotide binding protein (G protein), gamma
2 [Homo sapiens]
Length = 71
Score = 109 bits (273), Expect = 4e-25
Identities = 49/69 (71%), Positives = 62/69 (89%)
Query: 2 SNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFR 61
SNN A IA+ARK VEQLK+E NIDR+KVS+AAA+L+A+CE HAK+DPL+TPVPA+ENPFR
Sbjct: 3 SNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR 62
Query: 62 DKRLFCVLL 70
+K+ FC +L
Sbjct: 63 EKKFFCAIL 71
>gi|148922937 guanine nucleotide binding protein (G protein),
gamma 4 [Homo sapiens]
Length = 75
Score = 98.2 bits (243), Expect = 1e-21
Identities = 45/71 (63%), Positives = 59/71 (83%), Gaps = 1/71 (1%)
Query: 1 MSNNMA-KIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENP 59
MSNN I++ARK VEQLK+E +DR+KVSQAAA+LLA+CE H ++DPL+ PVPA+ENP
Sbjct: 5 MSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENP 64
Query: 60 FRDKRLFCVLL 70
FR+K+ FC +L
Sbjct: 65 FREKKFFCTIL 75
>gi|148922892 guanine nucleotide binding protein (G protein),
gamma 4 [Homo sapiens]
Length = 75
Score = 98.2 bits (243), Expect = 1e-21
Identities = 45/71 (63%), Positives = 59/71 (83%), Gaps = 1/71 (1%)
Query: 1 MSNNMA-KIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENP 59
MSNN I++ARK VEQLK+E +DR+KVSQAAA+LLA+CE H ++DPL+ PVPA+ENP
Sbjct: 5 MSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENP 64
Query: 60 FRDKRLFCVLL 70
FR+K+ FC +L
Sbjct: 65 FREKKFFCTIL 75
>gi|4758450 guanine nucleotide binding protein (G protein), gamma
4 [Homo sapiens]
Length = 75
Score = 98.2 bits (243), Expect = 1e-21
Identities = 45/71 (63%), Positives = 59/71 (83%), Gaps = 1/71 (1%)
Query: 1 MSNNMA-KIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENP 59
MSNN I++ARK VEQLK+E +DR+KVSQAAA+LLA+CE H ++DPL+ PVPA+ENP
Sbjct: 5 MSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENP 64
Query: 60 FRDKRLFCVLL 70
FR+K+ FC +L
Sbjct: 65 FREKKFFCTIL 75
>gi|6912394 guanine nucleotide binding protein (G protein), gamma
3 [Homo sapiens]
Length = 75
Score = 90.9 bits (224), Expect = 2e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Query: 3 NNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRD 62
N+ I +ARK VEQLK+E ++ R+KVS+AAA+L+ +C+ HA +DPL+TPVP +ENPFR+
Sbjct: 8 NSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSENPFRE 67
Query: 63 KRLFCVLL 70
K+ FC LL
Sbjct: 68 KKFFCALL 75
>gi|32698769 guanine nucleotide binding protein (G protein), gamma
7 [Homo sapiens]
Length = 68
Score = 81.3 bits (199), Expect = 2e-16
Identities = 36/63 (57%), Positives = 55/63 (87%), Gaps = 1/63 (1%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67
IA+ARK VEQL++E I+R+KVS+AA++L+++CE HA++DPL+ VPA+ENPF+DK+ C
Sbjct: 7 IAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFKDKKP-C 65
Query: 68 VLL 70
++L
Sbjct: 66 IIL 68
>gi|51036603 G-protein gamma-12 subunit [Homo sapiens]
Length = 72
Score = 80.5 bits (197), Expect = 3e-16
Identities = 34/63 (53%), Positives = 55/63 (87%), Gaps = 1/63 (1%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67
IA+AR+TV+QL+LE +I+R+KVS+A+A+L+++CE HA+ DPL+ +P +ENPF+DK+ C
Sbjct: 11 IAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKT-C 69
Query: 68 VLL 70
++L
Sbjct: 70 IIL 72
>gi|4885287 guanine nucleotide binding protein (G protein), gamma
5 [Homo sapiens]
Length = 68
Score = 62.0 bits (149), Expect = 1e-10
Identities = 28/60 (46%), Positives = 45/60 (75%)
Query: 6 AKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRL 65
+ +A +K V+QL+LE ++R+KVSQAAA+L FC +A+ DPL+T V ++ NPFR +++
Sbjct: 5 SSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKV 64
>gi|63055067 guanine nucleotide binding protein (G protein), gamma
10 [Homo sapiens]
Length = 68
Score = 62.0 bits (149), Expect = 1e-10
Identities = 33/65 (50%), Positives = 43/65 (66%), Gaps = 1/65 (1%)
Query: 6 AKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRL 65
A + ++ VEQLKLE ++R+KVSQAAAEL +C +A D L+ VPA NPFR+ R
Sbjct: 5 ASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPR- 63
Query: 66 FCVLL 70
C LL
Sbjct: 64 SCALL 68
>gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]
Length = 69
Score = 55.8 bits (133), Expect = 7e-09
Identities = 27/62 (43%), Positives = 42/62 (67%), Gaps = 3/62 (4%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67
I +A VEQL++E ID++K+ AA+LL FC AK+DP + +PAA N F++K+ +
Sbjct: 11 IGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKKPYA 67
Query: 68 VL 69
+L
Sbjct: 68 IL 69
>gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]
Length = 69
Score = 55.8 bits (133), Expect = 7e-09
Identities = 27/62 (43%), Positives = 42/62 (67%), Gaps = 3/62 (4%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67
I +A VEQL++E ID++K+ AA+LL FC AK+DP + +PAA N F++K+ +
Sbjct: 11 IGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKKPYA 67
Query: 68 VL 69
+L
Sbjct: 68 IL 69
>gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]
Length = 69
Score = 55.8 bits (133), Expect = 7e-09
Identities = 27/62 (43%), Positives = 42/62 (67%), Gaps = 3/62 (4%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67
I +A VEQL++E ID++K+ AA+LL FC AK+DP + +PAA N F++K+ +
Sbjct: 11 IGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKKPYA 67
Query: 68 VL 69
+L
Sbjct: 68 IL 69
>gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo
sapiens]
Length = 68
Score = 51.6 bits (122), Expect = 1e-07
Identities = 29/56 (51%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Query: 15 VEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVLL 70
VEQLKLE ++R+ VSQAAAEL +C +A D L+ V A NPF + R C LL
Sbjct: 14 VEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWEPR-SCALL 68
>gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo
sapiens]
Length = 68
Score = 51.6 bits (122), Expect = 1e-07
Identities = 29/56 (51%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Query: 15 VEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVLL 70
VEQLKLE ++R+ VSQAAAEL +C +A D L+ V A NPF + R C LL
Sbjct: 14 VEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWEPR-SCALL 68
>gi|11386179 guanine nucleotide binding protein (G protein), gamma
transducing activity polypeptide 1 [Homo sapiens]
Length = 74
Score = 48.1 bits (113), Expect = 1e-06
Identities = 22/55 (40%), Positives = 36/55 (65%)
Query: 15 VEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVL 69
V+QLK EV ++RM VS+ E+ + E + +DPLV +P +NPF++ + CV+
Sbjct: 19 VDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPEDKNPFKELKGGCVI 73
>gi|4758448 guanine nucleotide binding protein gamma 11 precursor
[Homo sapiens]
Length = 73
Score = 46.2 bits (108), Expect = 6e-06
Identities = 20/49 (40%), Positives = 33/49 (67%)
Query: 15 VEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDK 63
VEQL+ EV + R +VS+ + E+ + E + +DPLV +P +NPF++K
Sbjct: 19 VEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPEDKNPFKEK 67
>gi|14589849 guanine nucleotide binding protein-gamma transducing
activity polypeptide 2 [Homo sapiens]
Length = 69
Score = 45.1 bits (105), Expect = 1e-05
Identities = 21/63 (33%), Positives = 38/63 (60%)
Query: 1 MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60
M+ ++++ + VEQLK EV R+ +S+A E+ + E A +DP + +P +NPF
Sbjct: 1 MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF 60
Query: 61 RDK 63
++K
Sbjct: 61 KEK 63
>gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]
Length = 153
Score = 45.1 bits (105), Expect = 1e-05
Identities = 24/46 (52%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Query: 25 DRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFCVLL 70
+ +KVSQAAAEL +C +A D L+ VPA NPFR+ R C LL
Sbjct: 109 ETLKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPR-SCALL 153
>gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]
Length = 472
Score = 33.9 bits (76), Expect = 0.028
Identities = 16/51 (31%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 10 EARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60
+ RK + L +++ +K+S+ A L+A+ E + + DPL+TP + NP+
Sbjct: 260 DIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLITPAEPS-NPW 309
>gi|7706567 guanine nucleotide binding protein (G protein), gamma
13 [Homo sapiens]
Length = 67
Score = 33.1 bits (74), Expect = 0.048
Identities = 17/56 (30%), Positives = 27/56 (48%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDK 63
+ + +K VE LK ++ R S+ ELL + E DP + P NP+ +K
Sbjct: 6 VPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEK 61
>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
Length = 487
Score = 31.2 bits (69), Expect = 0.18
Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 10 EARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60
E ++ ++ +++++ R+K+S+ A LL++ E + + DP + P P NP+
Sbjct: 257 ELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP-PDPSNPW 306
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 29.3 bits (64), Expect = 0.70
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 7 KIAEARKTVEQLKLEVNIDRMKVS---QAAAELLAFCETHAKDDPLVTPVPAAENPFRDK 63
K+ K ++QL+ +V+ D M + A+ L +F E + D P T VPA FR
Sbjct: 6768 KVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRAKFRAV 6827
Query: 64 R 64
R
Sbjct: 6828 R 6828
>gi|33624861 spectrin repeat containing, nuclear envelope 2 isoform
2 [Homo sapiens]
Length = 429
Score = 29.3 bits (64), Expect = 0.70
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 7 KIAEARKTVEQLKLEVNIDRMKVS---QAAAELLAFCETHAKDDPLVTPVPAAENPFRDK 63
K+ K ++QL+ +V+ D M + A+ L +F E + D P T VPA FR
Sbjct: 290 KVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPAPRAKFRAV 349
Query: 64 R 64
R
Sbjct: 350 R 350
>gi|221307502 WEE1 tyrosine kinase isoform 2 [Homo sapiens]
Length = 432
Score = 26.6 bits (57), Expect = 4.5
Identities = 11/29 (37%), Positives = 20/29 (68%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAEL 36
++ +RK+ EQL++E+N ++ K S EL
Sbjct: 356 LSASRKSAEQLRIELNAEKFKNSLLQKEL 384
>gi|4507917 WEE1 tyrosine kinase isoform 1 [Homo sapiens]
Length = 646
Score = 26.6 bits (57), Expect = 4.5
Identities = 11/29 (37%), Positives = 20/29 (68%)
Query: 8 IAEARKTVEQLKLEVNIDRMKVSQAAAEL 36
++ +RK+ EQL++E+N ++ K S EL
Sbjct: 570 LSASRKSAEQLRIELNAEKFKNSLLQKEL 598
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 26.2 bits (56), Expect = 5.9
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 7 KIAEARKTVEQLKLEVNIDRMKVS---QAAAELLAFCETHAKDDPLVTPVPA 55
K+ K ++QL+ +V+ D M + A+ L +F E + D P T VPA
Sbjct: 6745 KVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPA 6796
>gi|33624873 spectrin repeat containing, nuclear envelope 2 isoform
4 [Homo sapiens]
Length = 556
Score = 26.2 bits (56), Expect = 5.9
Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 7 KIAEARKTVEQLKLEVNIDRMKVS---QAAAELLAFCETHAKDDPLVTPVPA 55
K+ K ++QL+ +V+ D M + A+ L +F E + D P T VPA
Sbjct: 416 KVHVIEKKLKQLREQVSQDLMALQGTQNPASPLPSFDEVDSGDQPPATSVPA 467
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.131 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,165,980
Number of Sequences: 37866
Number of extensions: 61238
Number of successful extensions: 251
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 224
Number of HSP's gapped (non-prelim): 28
length of query: 70
length of database: 18,247,518
effective HSP length: 43
effective length of query: 27
effective length of database: 16,619,280
effective search space: 448720560
effective search space used: 448720560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.