BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|151301096 trimethylguanosine synthase homolog [Homo sapiens] (853 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|151301096 trimethylguanosine synthase homolog [Homo sapiens] 1746 0.0 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 60 7e-09 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 57 9e-08 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 48 3e-05 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 48 3e-05 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 6e-05 gi|221219020 NYD-SP11 protein [Homo sapiens] 47 8e-05 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 45 2e-04 gi|217330641 IWS1 homolog [Homo sapiens] 43 0.001 gi|125656165 THO complex 2 [Homo sapiens] 42 0.002 gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 42 0.002 gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 42 0.002 gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 41 0.004 gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 41 0.004 gi|16445033 ACRC protein [Homo sapiens] 41 0.004 gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 40 0.007 gi|62750354 matrin 3 [Homo sapiens] 40 0.007 gi|21626466 matrin 3 [Homo sapiens] 40 0.007 gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 40 0.009 gi|50962882 G patch domain containing 8 [Homo sapiens] 40 0.012 gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 39 0.020 gi|55741677 SET domain containing 1A [Homo sapiens] 39 0.020 gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.020 gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.020 gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.020 gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.020 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 39 0.027 gi|24415404 MDN1, midasin homolog [Homo sapiens] 38 0.046 gi|110349756 zygin 2 isoform 2 [Homo sapiens] 38 0.046 gi|110349754 zygin 2 isoform 1 [Homo sapiens] 38 0.046 >gi|151301096 trimethylguanosine synthase homolog [Homo sapiens] Length = 853 Score = 1746 bits (4523), Expect = 0.0 Identities = 853/853 (100%), Positives = 853/853 (100%) Query: 1 MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT 60 MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT Sbjct: 1 MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT 60 Query: 61 EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN 120 EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN Sbjct: 61 EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN 120 Query: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE Sbjct: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180 Query: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH 240 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH Sbjct: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH 240 Query: 241 YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI 300 YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI Sbjct: 241 YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI 300 Query: 301 MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS 360 MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS Sbjct: 301 MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS 360 Query: 361 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK Sbjct: 361 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420 Query: 421 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK Sbjct: 421 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480 Query: 481 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV Sbjct: 481 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540 Query: 541 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ Sbjct: 541 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600 Query: 601 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD 660 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD Sbjct: 601 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD 660 Query: 661 GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI 720 GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI Sbjct: 661 GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI 720 Query: 721 DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR 780 DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR Sbjct: 721 DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR 780 Query: 781 TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA 840 TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA Sbjct: 781 TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA 840 Query: 841 YFGDLIRRPASET 853 YFGDLIRRPASET Sbjct: 841 YFGDLIRRPASET 853 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 60.5 bits (145), Expect = 7e-09 Identities = 74/372 (19%), Positives = 132/372 (35%), Gaps = 12/372 (3%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+D+ S + +D + + D SS +DSS +SD S S Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSS-DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + K +S ++S+ DS S D S+ +S S S+ N + +S+ S +++ Sbjct: 621 DSKSDS---SKSESDSSDS-DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 + DS SS ++ S D ++S + D S S+ D D + +SD D Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736 Query: 443 SGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESE 502 S + S + S + + S D + + Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS--DSSDSSNSSDSNDSSNSSDS 794 Query: 503 KPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDL 562 S + + + + D S +SS+ + D+S SSDS + S G D Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS-SDGSDS 853 Query: 563 LETNNPEPEKCQSVSSAGELETENYERDSL----LATVPDEQDCVTQEVPDSRQAETEAE 618 +N + S + + + DS + D D DS + ++ Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913 Query: 619 VKKKKNKKKNKK 630 N + + Sbjct: 914 SSDSSNSSDSSE 925 Score = 59.3 bits (142), Expect = 1e-08 Identities = 64/329 (19%), Positives = 116/329 (35%), Gaps = 28/329 (8%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+ ++ ++++D ++ S SS +DSS +SD D S D + Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + + + DS S DG + +S +S+ N + +S+ S N++ Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDG----------SDSDSSNRSDSSNSSDSSDSSDSSNSSD 878 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 + DS +SS ++ S D ++S +D +S S S E + ++ D Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938 Query: 443 SGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESE 502 S N S N S D + + + +S Sbjct: 939 S------------------NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 503 KPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDL 562 S + + D S +SS N D+S SSDS S D Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040 Query: 563 LETNNPEPEKCQSVSSAGELETENYERDS 591 +++ + S++ + + DS Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069 Score = 55.5 bits (132), Expect = 2e-07 Identities = 41/182 (22%), Positives = 70/182 (38%), Gaps = 1/182 (0%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321 D+S S D+ + +++ D +D S SS +DSS +SD D S+ D Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 322 SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381 + + + DS S D S +S S+ + + +S+ S +++ Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + DS SS ++ S D +S + D E S D + +SD Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172 Query: 442 DS 443 DS Sbjct: 1173 DS 1174 Score = 55.1 bits (131), Expect = 3e-07 Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 4/185 (2%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+ + +++ D +D S SS +DSS +SD S S Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091 Query: 323 NIKLNSEEVTQS----QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378 N +S+ S DS S D + S +S S+ N + +S+ S Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151 Query: 379 NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPAS 438 +++ + DS SS ++ S D +S + D + S D + +S Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211 Query: 439 DFDDS 443 D DS Sbjct: 1212 DSSDS 1216 Score = 54.3 bits (129), Expect = 5e-07 Identities = 60/300 (20%), Positives = 102/300 (34%), Gaps = 19/300 (6%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321 D+S S D+ + +++ D +D S SS +DSS +SD D S+ D Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079 Query: 322 SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381 + + + + + DS S D S +S S + + +S+ S +++ Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + DS +SS ++ S D +S + D + S D + +SD Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199 Query: 442 DSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKES 501 DS S + S + N S + S Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS------------------SDSS 1241 Query: 502 EKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDD 561 + S S + DE SQ S + N + + + SDSE D + DD Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 53.5 bits (127), Expect = 8e-07 Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 1/181 (0%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+D+ + + + D +D S SS +DSS +SD S S Sbjct: 896 DSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + +S+ S S D + S +S S+ + + +S+ S +++ Sbjct: 955 DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 + DS SS ++ S D +S + D + S D + +SD D Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074 Query: 443 S 443 S Sbjct: 1075 S 1075 Score = 53.5 bits (127), Expect = 8e-07 Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 2/181 (1%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+ + +++ D +D S SS +DSS +SD +S S Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + +S+ S DS S + S +S S+ + + +S+ S N++ Sbjct: 1038 DSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 + DS SS ++ S D +S + D + S + D + +SD D Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155 Query: 443 S 443 S Sbjct: 1156 S 1156 Score = 52.4 bits (124), Expect = 2e-06 Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S D+ ++ +++ + +D S SS +DSS +SD +S S Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064 Query: 323 NIKLNSEEVTQS-QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381 + +S+ S DS S D + S +S S+ + + +S+ S N++ Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + DS SS ++ S D +S + D + S D + +SD Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184 Query: 442 DS 443 DS Sbjct: 1185 DS 1186 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/195 (23%), Positives = 72/195 (36%), Gaps = 10/195 (5%) Query: 261 TFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDG 320 T D + S + + +DK+D K D SS +DSS +SD D S+ Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577 Query: 321 ISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSS--- 377 + +S+ S DS S + S +S S+ ++ + ES+SS Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637 Query: 378 -------GNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHEL 430 N++ DS SS ++ S D +S + S D S Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697 Query: 431 DIDENPASDFDDSGS 445 + + +SD DS S Sbjct: 698 SSESSDSSDSSDSDS 712 Score = 50.8 bits (120), Expect = 5e-06 Identities = 40/184 (21%), Positives = 72/184 (39%), Gaps = 5/184 (2%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321 D+S S D+ S +D N S SS +DSS +SD D S+ D Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSD----SSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016 Query: 322 SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381 ++ ++ + + DS S D S +S S+ + + +S+ S +++ Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + +S SS ++ S D +S + D + S + D + +SD Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136 Query: 442 DSGS 445 DS + Sbjct: 1137 DSSN 1140 Score = 50.4 bits (119), Expect = 7e-06 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 8/195 (4%) Query: 257 AQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSE 316 + G D+S D+ + +++ D ++ S SS +DSS +SD D S+ Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907 Query: 317 ILDGI-SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVS-----SKRECPASGQSEPRNGGT 370 + S+ NS + ++S S S+ S S S +S S+ N Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967 Query: 371 NEESNSSGNTNTDPPAE--DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSH 428 + +SNSS ++++ ++ DS SS ++ S D ++S + D S Sbjct: 968 SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027 Query: 429 ELDIDENPASDFDDS 443 D + +SD DS Sbjct: 1028 SNSSDSSDSSDSSDS 1042 Score = 50.4 bits (119), Expect = 7e-06 Identities = 39/183 (21%), Positives = 73/183 (39%), Gaps = 3/183 (1%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+S S ++ + + + D ++ S SS +DSS +SD +S D Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS--DSSD 970 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + +S + + S DS S D S +S S+ + + +S++S +++ Sbjct: 971 SNSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 + DS SS ++ S D +S + D + S D + +SD D Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089 Query: 443 SGS 445 S + Sbjct: 1090 SSN 1092 Score = 50.4 bits (119), Expect = 7e-06 Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 4/185 (2%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD----KDHSEIL 318 D+S S D+ + +++ + +D S SS +DSS +SD D S+ Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043 Query: 319 DGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378 D + + + DS S D S +S S+ N + +S+ S Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103 Query: 379 NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPAS 438 +++ + DS SS ++ S D +S + + + S D + +S Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163 Query: 439 DFDDS 443 D DS Sbjct: 1164 DSSDS 1168 Score = 49.3 bits (116), Expect = 2e-05 Identities = 43/189 (22%), Positives = 70/189 (37%), Gaps = 16/189 (8%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 ++S S D + + + D +D S SS +DSS +SD S D S Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSD------SSNSSDSSNSSDSSNSSDSSDSNSSD--S 976 Query: 323 NIKLNSEEVTQS--------QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEES 374 + NS + + S DS S D S +S S+ N + +S Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036 Query: 375 NSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDE 434 + S +++ + DS SS ++ S D +S + D + S D Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096 Query: 435 NPASDFDDS 443 + +SD DS Sbjct: 1097 SDSSDSSDS 1105 Score = 48.5 bits (114), Expect = 3e-05 Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 11/183 (6%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 DA+ D ++ +S+ +A +DE D + S D+DS TSD ++S D Sbjct: 476 DANSESDNNS-SSRGDASYNSDES---KDNGNGSDSKGAEDDDSDSTSDTNNS---DSNG 528 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 N +++ +S S S+ S+ + S S+ + ++ +S+SS + ++ Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442 D DS SS ++ S D S D S+ S +S D + SD D Sbjct: 589 DSSDSDSSDSSNSSDSSD----SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644 Query: 443 SGS 445 S S Sbjct: 645 SNS 647 Score = 37.0 bits (84), Expect = 0.078 Identities = 72/385 (18%), Positives = 131/385 (34%), Gaps = 40/385 (10%) Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIM--VDNDSSGTSDKDHSEILDGISNIKLNSE 329 T S+T A K+ +K +++ S + I V + G DK ++ G N+K E Sbjct: 360 TKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGE 419 Query: 330 ---------------EVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNE-- 372 +V S S ++ DG+ + S+ NG + Sbjct: 420 VVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANS 479 Query: 373 -----------------ESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEED 415 ES +GN + AED S ++T+ + +G +G++ + D Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND-DND 538 Query: 416 PPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNV 475 + K S D + +SD DS S + S + Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598 Query: 476 KLKSKYLDMRRQIKMKNKHIFFTKESE--KPFFKKSKILSKVEKFLTWVNKPMDEEASQE 533 S D + +S+ K S SK + + + D S + Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658 Query: 534 SSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLL 593 SS+ N D+S SSDS + S + ++++ S SS +++ DS Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSS-SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717 Query: 594 ATVPDEQDCVTQEVPDSRQAETEAE 618 ++ + D + DS + ++ Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSD 742 Score = 35.0 bits (79), Expect = 0.30 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 22/180 (12%) Query: 320 GISNIKLNSEEVTQSQLDSCTSHDGHQQLS-EVSSKRECPASGQSEPRNGGTNEESNSSG 378 G +N N +E+ ++ SC + +++ +++SKR + P G NS G Sbjct: 188 GSNNSTDNEDEIIEN---SCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDG 244 Query: 379 NTNTDPPAEDSQKSSG------ANTSKDRPHAS----GTD-GDESEEDPPEHKPSKLKRS 427 + + + ED + SG A KD + S G D G E + D + S K Sbjct: 245 SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY 304 Query: 428 HELDIDENPASDFDDSGSLLGFKYGSG-------QKYGGIPNFSHRQVRYLEKNVKLKSK 480 ++ + E+P ++ D + + +G Q+ +HR+ + +E + +S+ Sbjct: 305 YDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESE 364 Score = 32.3 bits (72), Expect = 1.9 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 4/101 (3%) Query: 524 KPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELE 583 K + + +SS N D+S SSDS+ D + D ++++ + S S+ + Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603 Query: 584 TENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKN 624 + + S + D D + DS ++E+++ K+ Sbjct: 604 SSDSSDSSDSSDSSDSSDSKS----DSSKSESDSSDSDSKS 640 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 56.6 bits (135), Expect = 9e-08 Identities = 75/292 (25%), Positives = 133/292 (45%), Gaps = 16/292 (5%) Query: 346 QQLSEVSSKRECPASGQSEPRNGGTNEES-NSSGNTNTDPPAEDSQKSSGANTSKDRPHA 404 +Q+ E +KR+ A ++ ++ NE+S S ++ T+P +++S+ S + KD+ + Sbjct: 145 KQIVEEKTKRQNEAD-KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDS 203 Query: 405 SGTDGDESEEDPPEHKPSK-LKRSHELDIDENPASDFDDSGSL-LGFKYGSGQKYGGIPN 462 + +E ++ P K LKRS +P S+ SL + F GQ N Sbjct: 204 KNSKKTNTEFLHTKNNPKKDLKRS---KTSNDPISEICSENSLNVDFLMLVGQSDDESIN 260 Query: 463 FSHRQVRYLEKNVKLKS-KYLDMRRQIKMKNKHIFFTKESE--KPFFKKSKILSKVEKFL 519 F Y + N K S KY ++ KN ESE K K SK KV+K + Sbjct: 261 FDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSK---KVKKNV 317 Query: 520 TWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSA 579 +K D + ES+ ++ D+++ +KK DD + PE + S Sbjct: 318 KKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK-DDKKKDTKKYPESTDTESGD 376 Query: 580 GELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKK-KKNKKKNKK 630 + + N R+ A+ D++ +++ S +E+E E K+ +K++KK+KK Sbjct: 377 AK-DARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKK 427 Score = 33.9 bits (76), Expect = 0.66 Identities = 56/266 (21%), Positives = 96/266 (36%), Gaps = 26/266 (9%) Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELD 431 E S P +DS+K G+ + S +E + E + LK SHE + Sbjct: 114 EYKKSKDEKGGTPLKKDSKKKGGSYATNPE---SKQIVEEKTKRQNEADKTPLKSSHENE 170 Query: 432 IDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMK 491 + S + + K S N S + + + + K +++L + K Sbjct: 171 QSKKSKSSSETNPESQNSKTVS-------KNCSQKDKKDSKNSKKTNTEFLHTKNNPKKD 223 Query: 492 NKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDE----EASQESSSHDNVHDAS--- 544 K +K S P + S FL V + DE +A + S +N + S Sbjct: 224 LKR---SKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280 Query: 545 TSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVT 604 T ++ + KK D E E + + +N ++D V + + Sbjct: 281 TKYTKKDTKKNAKKSSDA------ESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTD 334 Query: 605 QEVPDSRQAETEAEVKKKKNKKKNKK 630 E DS+ + + KKK KK +KK Sbjct: 335 AESGDSKDERKDTKKDKKKLKKDDKK 360 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 48.1 bits (113), Expect = 3e-05 Identities = 71/347 (20%), Positives = 133/347 (38%), Gaps = 40/347 (11%) Query: 297 SSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRE 356 S P+ VD+D ++ + IK N + DG K+ Sbjct: 1215 SVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS----------SDEDGSSDDEPEEGKKR 1264 Query: 357 CPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANT--SKDRPHASGTDGDESEE 414 +G+ N G +EE+ + N+ +D +E+S+K + + G G+E + Sbjct: 1265 ---TGKQNEENPG-DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1320 Query: 415 DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474 P EHK K + ++ +++ SDF +SG ++ + ++ +++ Sbjct: 1321 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1380 Query: 475 VKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQES 534 K K K RR+IK+ +E K + + EK + +EE +E Sbjct: 1381 YKQKKK----RRRIKV--------QEDSSSENKSNSEEEEEEK-----EEEEEEEEEEEE 1423 Query: 535 SSHDNVHDASTSSDSEEQDMSVKKGDDL-LETNNPEPEKCQSVSSAGELETENYERDSLL 593 D D+ + ++ + K D L ET N E+ + E E E + ++ Sbjct: 1424 EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVI 1483 Query: 594 A---TVPDEQDCVTQEVPDSRQAETEAEVKKKKN---KKKNKKVNGL 634 P + T+ V D + E V+ +N K K +V+G+ Sbjct: 1484 EIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1530 Score = 30.0 bits (66), Expect = 9.5 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Query: 326 LNSEEVTQSQLDSCTS--HDGHQQLSEVSSKRECP---ASGQSEPRNGGTNEESNSSGNT 380 + +E +++S+L++ HD SE S + P A Q+ + G+ S+ N+ Sbjct: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60 Query: 381 NTD-PPAEDSQKSSGANTSKDRPHASGTDGDESEEDPP 417 + + + KSSG++ SK +P + T ES+++ P Sbjct: 61 KEEGTSSSEKSKSSGSSRSKRKP-SIVTKYVESDDEKP 97 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 48.1 bits (113), Expect = 3e-05 Identities = 71/347 (20%), Positives = 133/347 (38%), Gaps = 40/347 (11%) Query: 297 SSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRE 356 S P+ VD+D ++ + IK N + DG K+ Sbjct: 1253 SVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS----------SDEDGSSDDEPEEGKKR 1302 Query: 357 CPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANT--SKDRPHASGTDGDESEE 414 +G+ N G +EE+ + N+ +D +E+S+K + + G G+E + Sbjct: 1303 ---TGKQNEENPG-DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1358 Query: 415 DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474 P EHK K + ++ +++ SDF +SG ++ + ++ +++ Sbjct: 1359 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1418 Query: 475 VKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQES 534 K K K RR+IK+ +E K + + EK + +EE +E Sbjct: 1419 YKQKKK----RRRIKV--------QEDSSSENKSNSEEEEEEK-----EEEEEEEEEEEE 1461 Query: 535 SSHDNVHDASTSSDSEEQDMSVKKGDDL-LETNNPEPEKCQSVSSAGELETENYERDSLL 593 D D+ + ++ + K D L ET N E+ + E E E + ++ Sbjct: 1462 EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVI 1521 Query: 594 A---TVPDEQDCVTQEVPDSRQAETEAEVKKKKN---KKKNKKVNGL 634 P + T+ V D + E V+ +N K K +V+G+ Sbjct: 1522 EIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1568 Score = 30.0 bits (66), Expect = 9.5 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Query: 326 LNSEEVTQSQLDSCTS--HDGHQQLSEVSSKRECP---ASGQSEPRNGGTNEESNSSGNT 380 + +E +++S+L++ HD SE S + P A Q+ + G+ S+ N+ Sbjct: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60 Query: 381 NTD-PPAEDSQKSSGANTSKDRPHASGTDGDESEEDPP 417 + + + KSSG++ SK +P + T ES+++ P Sbjct: 61 KEEGTSSSEKSKSSGSSRSKRKP-SIVTKYVESDDEKP 97 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 47.4 bits (111), Expect = 6e-05 Identities = 81/379 (21%), Positives = 148/379 (39%), Gaps = 55/379 (14%) Query: 256 EAQGWTFDASQSCDTDTYTSKTEADDKNDEKC-MKVDLVSFPSSPIMVDNDSSGTSDKDH 314 EAQG D T ++ E K+ +K K SF DNDS DKD Sbjct: 68 EAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFD------DNDSEELEDKDS 121 Query: 315 SEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEES 374 S++ + +++ + D +++ K + A ++ +G +E Sbjct: 122 K------------SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169 Query: 375 NSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDE 434 NS + R ++SG GDES+E K K + ++ + Sbjct: 170 NSK-----------------KIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212 Query: 435 NPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKH 494 ++ DD+ FK + + R+ R E K K + L + +++ K Sbjct: 213 ESGNEDDDA----SFKIKTVAQKKAEKKERERKKRDEE---KAKLRKLKEKEELETGKKD 265 Query: 495 IFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDM 554 KES++ F++ + SKV T V +E+A +++ D+ D +++D Sbjct: 266 QSKQKESQRK-FEEETVKSKV-TVDTGVIPASEEKAETPTAAEDD-----NEGDKKKKDK 318 Query: 555 SVKKGDDLLETNNPEPEKCQS---VSSAGELETENYERDSLLATVPDEQDCVTQEVPDSR 611 KKG+ E E +K S V + E + E + +E+ +E+ R Sbjct: 319 KKKKGEK--EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376 Query: 612 QAETEAEVKKKKNKKKNKK 630 + E E +K++ KK+ +K Sbjct: 377 KEEERLEQEKRERKKQKEK 395 Score = 37.0 bits (84), Expect = 0.078 Identities = 52/277 (18%), Positives = 103/277 (37%), Gaps = 39/277 (14%) Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468 G E++P + K K K + D DE+ + SL + ++ + + + Sbjct: 30 GAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEE 89 Query: 469 RYLEKNVKLKSKY----------------LDMRRQIKMKNKHIFFTKESEKPFFKK--SK 510 + K+ K K + D + + K K ++ + F K K Sbjct: 90 EFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK 149 Query: 511 ILSKVEKF-LTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPE 569 K +K W DE+ S++ ++ + S D ++ + +KG + N P Sbjct: 150 AKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPG 209 Query: 570 PE--------------KCQSVSSAGELETENYERD---SLLATVPDEQDCVTQEVPDSRQ 612 P K + A + E E +RD + L + ++++ T + S+Q Sbjct: 210 PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQ 269 Query: 613 AETEAEVKKKKNKKKNKKVNGLPP---EIAAVPELAK 646 E++ + +++ K K G+ P E A P A+ Sbjct: 270 KESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306 Score = 31.6 bits (70), Expect = 3.3 Identities = 105/555 (18%), Positives = 205/555 (36%), Gaps = 88/555 (15%) Query: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180 K K KKKK +KK ++++EDDIL + S+E E + K TE Sbjct: 39 KSKGKKKKEKKK-----------QDFDEDDILKELEELSLEAQGIKADRETVAVK--PTE 85 Query: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSS-EPWNFPDTKEEWEQ 239 N E T K + +K +K + + K A E ++ D +++ + Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNK 145 Query: 240 HYSQLYWYYLEQFQYWEAQGWTFDASQSC-DTDTYTSKTEADDKNDE-----KCMKVDLV 293 + + + W+ D S+ + S E+ D++DE K K + Sbjct: 146 LPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQK 205 Query: 294 SFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSS 353 + P N SG D D S + ++ K +E + + D + +L ++ Sbjct: 206 NKPG-----PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD-----EEKAKLRKLKE 255 Query: 354 KRECPA-----SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTD 408 K E S Q E + E S +T +K+ ++D + Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAED-----DNE 310 Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468 GD+ ++D + K K ++ E + A+ +L K RQ Sbjct: 311 GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK-----------EEEERQK 359 Query: 469 RYLEKNVK---------LKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK-- 517 R E+ +K + + L+ ++ + K K KE ++ K+ K+L+K ++ Sbjct: 360 REEEERIKRLEELEAKRKEEERLEQEKRERKKQKE----KERKERLKKEGKLLTKSQREA 415 Query: 518 -----------FLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQD----MSVKKGDDL 562 V P + ++ +++ E ++ M + ++ Sbjct: 416 RARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEV 475 Query: 563 LETNNPEPEKC-QSVSSAGELETENYERDSLLATVPDEQ------DCVTQEVPDSRQAET 615 +E PE E+ V E +TE+ D A DE+ + V EV ++ + E Sbjct: 476 MEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEE 535 Query: 616 EAEVKKKKNKKKNKK 630 E E +++++++ ++ Sbjct: 536 EEEEEEEEDEESEEE 550 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 47.0 bits (110), Expect = 8e-05 Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 33/191 (17%) Query: 472 EKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEAS 531 E+ + ++ LD++ + K TK+ +K K+ K+ +K+ + + K +EE+ Sbjct: 2108 ERRLSIEQSKLDIK-EWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166 Query: 532 QESSSHDNVHDASTSSDSEEQDM------------SVKKGD------------------- 560 + + D EE+++ K+GD Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF 2226 Query: 561 -DLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEV 619 + +E+ E EK +S+SS E E E E +E++ +E + +Q E E E Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286 Query: 620 KKKKNKKKNKK 630 KKKK K+K K+ Sbjct: 2287 KKKKKKEKKKE 2297 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 45.4 bits (106), Expect = 2e-04 Identities = 75/387 (19%), Positives = 139/387 (35%), Gaps = 45/387 (11%) Query: 48 IRDSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRIT 107 + ++GN D EE A + K I + S+ + E E Sbjct: 319 LEETGNQHNDVEIEE---------AGEEEEKEIAIVHSDAEKEQEEEEQK---------- 359 Query: 108 AHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQ-----ESWRKEYEEDDILASDDPSSIEQ 162 ++ EV M +V+ + +K Q +E++ E+ + + +++ ++ S+E Sbjct: 360 --QEMEVKMEEETEVR-ESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEP 416 Query: 163 YENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQA 222 EN + EL+ + + E E +LSP E N + +S +++ Sbjct: 417 SENEASKELEPEMEFEIEPDKECKSLSPGKE---------NVSALDMEKESEEKEEKESE 467 Query: 223 LSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDK 282 EP P + + + L+ + + + Q T ++ Sbjct: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPER 527 Query: 283 NDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSH 342 D V L P P++ + S + K S N S + S S +S Sbjct: 528 KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSS- 586 Query: 343 DGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRP 402 S SS +SG S R+ ++ S++SG+++ D + S S + S+ R Sbjct: 587 ------STSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRG 639 Query: 403 HASGTDGDESEEDPPEHKPSKLKRSHE 429 H S D S L+RSH+ Sbjct: 640 HNRDRKHRRS-VDRKRRDTSGLERSHK 665 Score = 37.4 bits (85), Expect = 0.059 Identities = 37/181 (20%), Positives = 78/181 (43%), Gaps = 23/181 (12%) Query: 463 FSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWV 522 F R++ + E+ K++++ RRQ + +H E +K ++ K+ + Sbjct: 267 FEGRRIEFAEQINKMEAR---PRRQSMKEKEHQVVRNEEQKAEQEEGKVAQR-------- 315 Query: 523 NKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGEL 582 +EE + + H++V + + + EE+++++ D E E E+ Q + E Sbjct: 316 ----EEELEETGNQHNDV-EIEEAGEEEEKEIAIVHSD--AEKEQEEEEQKQEMEVKMEE 368 Query: 583 ETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKK-----NKKKNKKVNGLPPE 637 ETE E + + P+E V + V + + + EV + +N+ L PE Sbjct: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPE 428 Query: 638 I 638 + Sbjct: 429 M 429 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 42.7 bits (99), Expect = 0.001 Identities = 70/383 (18%), Positives = 140/383 (36%), Gaps = 28/383 (7%) Query: 276 KTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQ 335 K+ A D E +K + S S +++ + + +L +V+ S+ Sbjct: 166 KSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE 225 Query: 336 LDSCTSHDGHQQLSEVSSK-RECPASGQSEPRNGGTNEESNS------SGNTNTDPPAED 388 + H +E K R + + PR+ ++ E+ S + + DPP Sbjct: 226 SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPR-- 283 Query: 389 SQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLG 448 +Q S N +P S ++ + ++ P ++ H+ + + SD ++ G Sbjct: 284 NQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTE 343 Query: 449 FKYGSGQKYGGIPNFS-HRQVRYLEKNVKLK------SKYLDMRRQIKMKNKHIFFTKES 501 + S + H E++ K K K + + K K + +++ Sbjct: 344 MQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDE 403 Query: 502 EKPFFKKSKILSKVE------------KFLTWVNKPMDEEASQESSSHDNVHDASTSSDS 549 EK KKS+++S + K + +EEA +E S N SDS Sbjct: 404 EKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDS 463 Query: 550 EEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPD 609 E + D+ + E E+ + + +LE E E A D D + + Sbjct: 464 ESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHM 523 Query: 610 SRQAETEAEVKKKKNKKKNKKVN 632 ++ E +++KK+ ++ N Sbjct: 524 DFLSDFEMMLQRKKSMSGKRRRN 546 Score = 38.9 bits (89), Expect = 0.020 Identities = 67/333 (20%), Positives = 126/333 (37%), Gaps = 46/333 (13%) Query: 297 SSPIMVDNDSSGTSDKDHSEILDG--ISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354 ++P+ + DS + D +E G +++ +SE T + D GH + + Sbjct: 16 ATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPK--GHHVTDSENDE 73 Query: 355 RECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEE 414 + SE ++S+S +PPA DS+ H S ++ +E+ Sbjct: 74 PLNLNASDSESEELHRQKDSDSESEERAEPPASDSENED------VNQHGSDSESEETR- 126 Query: 415 DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474 + P SD ++ L G S + G S ++ L+K+ Sbjct: 127 -------------------KLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKS 167 Query: 475 VKLKSKYLD-MRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEE--AS 531 S+ D ++ QI ESE+P ++ E ++ EE Sbjct: 168 PASDSETEDALKPQIS--------DSESEEPPRHQASDSENEEPPKPRMSDSESEELPKP 219 Query: 532 QESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDS 591 Q S S +SDSE +++ + + ++ + +P + Q+ S E + DS Sbjct: 220 QVSDSESEEPPRHQASDSENEELPKPR---ISDSESEDPPRHQASDSENEELPKPRISDS 276 Query: 592 LLATVPDEQ--DCVTQEVPDSRQAETEAEVKKK 622 P Q D +E+P R +++E+E +K Sbjct: 277 ESEDPPRNQASDSENEELPKPRVSDSESEGPQK 309 >gi|125656165 THO complex 2 [Homo sapiens] Length = 1593 Score = 42.4 bits (98), Expect = 0.002 Identities = 60/283 (21%), Positives = 115/283 (40%), Gaps = 42/283 (14%) Query: 361 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420 G S N G+N SN + N ++ +K T P A G + +E P E + Sbjct: 1251 GNSSNGNSGSN--SNKAVKENDKEKGKEKEKEKKEKTPATTPEAR-VLGKDGKEKPKEER 1307 Query: 421 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480 P+K +++ E + P SD + K + +PN + + E+ K S+ Sbjct: 1308 PNKDEKARETK-ERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERERE-KEPSR 1365 Query: 481 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540 D+ +++K K K EK S + S V + + + +P E+ ++ +H + Sbjct: 1366 ERDIAKEMKSKEN----VKGGEKTPVSGS-LKSPVPR--SDIPEPEREQKRRKIDTHPSP 1418 Query: 541 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600 +ST DS + +K+ L N+ P +S E+ Sbjct: 1419 SHSSTVKDSL---IELKESSAKLYINHTPPPLSKS----------------------KER 1453 Query: 601 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG-----LPPEI 638 + +++ SR+ E E K +K++K+ K+ + +PP++ Sbjct: 1454 EMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDL 1496 >gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 42.0 bits (97), Expect = 0.002 Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 39/295 (13%) Query: 337 DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGAN 396 +S + + E S+ CP G + +EE N + D P ++S+K + N Sbjct: 451 ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKN 510 Query: 397 TSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQK 456 ++ A ++ D ++E E P+ K S E D ++ D + S + GS ++ Sbjct: 511 DCEENGLAKESEDDLNKESEEEVGPT--KESEEDDSEKESDEDCSEKQS----EDGSERE 564 Query: 457 YGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVE 516 + + LEK++ + ++ + K +SE F+ Sbjct: 565 F---------EENGLEKDLDEEGSEKELHENVLDKELE---ENDSENSEFEDD------- 605 Query: 517 KFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV 576 K +DEE S+ D + EE+D K DD + E + Sbjct: 606 ----GSEKVLDEEGSERE------FDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655 Query: 577 SSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKV 631 A + + E + D L +E D E D ++ E +A+ K ++ N+K+ Sbjct: 656 LEAADKKAEEGDADEKLF---EESDDKEDEDADGKEVE-DADEKLFEDDDSNEKL 706 >gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 42.0 bits (97), Expect = 0.002 Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 39/295 (13%) Query: 337 DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGAN 396 +S + + E S+ CP G + +EE N + D P ++S+K + N Sbjct: 451 ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKN 510 Query: 397 TSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQK 456 ++ A ++ D ++E E P+ K S E D ++ D + S + GS ++ Sbjct: 511 DCEENGLAKESEDDLNKESEEEVGPT--KESEEDDSEKESDEDCSEKQS----EDGSERE 564 Query: 457 YGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVE 516 + + LEK++ + ++ + K +SE F+ Sbjct: 565 F---------EENGLEKDLDEEGSEKELHENVLDKELE---ENDSENSEFEDD------- 605 Query: 517 KFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV 576 K +DEE S+ D + EE+D K DD + E + Sbjct: 606 ----GSEKVLDEEGSERE------FDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655 Query: 577 SSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKV 631 A + + E + D L +E D E D ++ E +A+ K ++ N+K+ Sbjct: 656 LEAADKKAEEGDADEKLF---EESDDKEDEDADGKEVE-DADEKLFEDDDSNEKL 706 >gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor [Homo sapiens] Length = 513 Score = 41.2 bits (95), Expect = 0.004 Identities = 44/184 (23%), Positives = 70/184 (38%), Gaps = 14/184 (7%) Query: 276 KTEADDKNDEKCMKVDLVSFPSSP----IMVDNDSSGTSDKDHSEIL--DGISNIKLNSE 329 ++E DD N + +K D +S DS G S +D E L + N+ S Sbjct: 279 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 338 Query: 330 EVTQSQLDSCTSHDGHQQLSEVSSKR---ECPASGQSEPRNGGTNEESNSS-----GNTN 381 E +Q S + Q VS R P + E + + E +SS + Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 398 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + DS+ S N S++ P + + S+E H S +S E +E+ + D Sbjct: 399 SREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 458 Query: 442 DSGS 445 S S Sbjct: 459 SSRS 462 Score = 40.4 bits (93), Expect = 0.007 Identities = 66/355 (18%), Positives = 137/355 (38%), Gaps = 46/355 (12%) Query: 303 DNDSSGT---SDKDHSEILDGISNIKLNSEEV-TQSQLDSCTSHDGHQQLSEVSSKRECP 358 D DS T S++ + D + S E+ + ++DS +G E S+ Sbjct: 137 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS--KPEGGDSTQESESEEHWV 194 Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQK-SSGANTSKDRPHASGTDGDESEEDPP 417 G + G E + G + DP + S++ +S N++ + SG + +++ Sbjct: 195 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 254 Query: 418 ------EHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYG------------- 458 EH K+ R + +E+ S+ DD+ ++ K S + Sbjct: 255 GGSQLLEHPSRKIFRKSRIS-EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 313 Query: 459 -GIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517 G ++ E++ + + ++ + ++ + ES++ +S+ + Sbjct: 314 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN--SSESQEEVVSESRG-DNPDP 370 Query: 518 FLTWVNKPMDEEASQESSSHDNVHDASTSSD-------SEEQDMSVKKGDDLLETNNPEP 570 ++V D ++S+E SSH H S S + SE + S + + + N+ Sbjct: 371 TTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQ 430 Query: 571 EKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNK 625 E QS SS+ E ++E + +E D +Q+ S++ E K + Sbjct: 431 EGLQSHSSSAESQSEE--------SHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477 Score = 35.4 bits (80), Expect = 0.23 Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 9/153 (5%) Query: 295 FPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354 F S I ++D S D + E + S NS + SQ + D + E S Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS- 326 Query: 355 RECPASGQSEPRN-GGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESE 413 Q E +N G + ES+ N ++ + +SQ+ + + D P + + ++ E Sbjct: 327 -------QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 379 Query: 414 EDPPEHKPSKLKRSHELDIDENPASDFDDSGSL 446 + + S SH +D + S SL Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSESL 412 Score = 33.5 bits (75), Expect = 0.86 Identities = 89/422 (21%), Positives = 150/422 (35%), Gaps = 69/422 (16%) Query: 50 DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109 D ++SGD +++ G + + +G DE DS+ + S Q G+ +A Sbjct: 104 DDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDE---DSDDTIQASEESAPQ-GQDSAQ 159 Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE-----------------EDDIL 152 S N+ ++ K + QES +E+ +D+ + Sbjct: 160 DTTSESRELDNEDRVDSKPEG----GDSTQESESEEHWVGGGSDGESSHGDGSELDDEGM 215 Query: 153 ASDDPSSIEQYE-NTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLW 211 SDDP SI N+R K EN NT + GG L Sbjct: 216 QSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT---------------QDSGGSQLL 260 Query: 212 QSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTD 271 + HP + + F ++ E S+L + E + + + S S DT Sbjct: 261 E-----HPSRKI------FRKSRISEEDDRSELD----DNNTMEEVKSDSTENSNSRDTG 305 Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEV 331 S+ D K D + + +S S VD SS +S + + L N + EEV Sbjct: 306 L--SQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEAN---LSSQENSSESQEEV 359 Query: 332 TQSQL----DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAE 387 D TS+ Q+ S+ S + S+ + +S SS + N + Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419 Query: 388 DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPA---SDFDDSG 444 +S + +++ + S + +SEE E S + S D N S ++ G Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 479 Query: 445 SL 446 L Sbjct: 480 QL 481 >gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 precursor [Homo sapiens] Length = 497 Score = 41.2 bits (95), Expect = 0.004 Identities = 44/184 (23%), Positives = 70/184 (38%), Gaps = 14/184 (7%) Query: 276 KTEADDKNDEKCMKVDLVSFPSSP----IMVDNDSSGTSDKDHSEIL--DGISNIKLNSE 329 ++E DD N + +K D +S DS G S +D E L + N+ S Sbjct: 263 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 322 Query: 330 EVTQSQLDSCTSHDGHQQLSEVSSKR---ECPASGQSEPRNGGTNEESNSS-----GNTN 381 E +Q S + Q VS R P + E + + E +SS + Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 382 Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441 + DS+ S N S++ P + + S+E H S +S E +E+ + D Sbjct: 383 SREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 442 Query: 442 DSGS 445 S S Sbjct: 443 SSRS 446 Score = 40.4 bits (93), Expect = 0.007 Identities = 66/355 (18%), Positives = 137/355 (38%), Gaps = 46/355 (12%) Query: 303 DNDSSGT---SDKDHSEILDGISNIKLNSEEV-TQSQLDSCTSHDGHQQLSEVSSKRECP 358 D DS T S++ + D + S E+ + ++DS +G E S+ Sbjct: 121 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS--KPEGGDSTQESESEEHWV 178 Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQK-SSGANTSKDRPHASGTDGDESEEDPP 417 G + G E + G + DP + S++ +S N++ + SG + +++ Sbjct: 179 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 238 Query: 418 ------EHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYG------------- 458 EH K+ R + +E+ S+ DD+ ++ K S + Sbjct: 239 GGSQLLEHPSRKIFRKSRIS-EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 297 Query: 459 -GIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517 G ++ E++ + + ++ + ++ + ES++ +S+ + Sbjct: 298 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN--SSESQEEVVSESRG-DNPDP 354 Query: 518 FLTWVNKPMDEEASQESSSHDNVHDASTSSD-------SEEQDMSVKKGDDLLETNNPEP 570 ++V D ++S+E SSH H S S + SE + S + + + N+ Sbjct: 355 TTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQ 414 Query: 571 EKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNK 625 E QS SS+ E ++E + +E D +Q+ S++ E K + Sbjct: 415 EGLQSHSSSAESQSEE--------SHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 461 Score = 35.4 bits (80), Expect = 0.23 Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 9/153 (5%) Query: 295 FPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354 F S I ++D S D + E + S NS + SQ + D + E S Sbjct: 252 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS- 310 Query: 355 RECPASGQSEPRN-GGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESE 413 Q E +N G + ES+ N ++ + +SQ+ + + D P + + ++ E Sbjct: 311 -------QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 363 Query: 414 EDPPEHKPSKLKRSHELDIDENPASDFDDSGSL 446 + + S SH +D + S SL Sbjct: 364 DSDSSEEDSSHTLSHSKSESREEQADSESSESL 396 Score = 33.5 bits (75), Expect = 0.86 Identities = 89/422 (21%), Positives = 150/422 (35%), Gaps = 69/422 (16%) Query: 50 DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109 D ++SGD +++ G + + +G DE DS+ + S Q G+ +A Sbjct: 88 DDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDE---DSDDTIQASEESAPQ-GQDSAQ 143 Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE-----------------EDDIL 152 S N+ ++ K + QES +E+ +D+ + Sbjct: 144 DTTSESRELDNEDRVDSKPEG----GDSTQESESEEHWVGGGSDGESSHGDGSELDDEGM 199 Query: 153 ASDDPSSIEQYE-NTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLW 211 SDDP SI N+R K EN NT + GG L Sbjct: 200 QSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT---------------QDSGGSQLL 244 Query: 212 QSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTD 271 + HP + + F ++ E S+L + E + + + S S DT Sbjct: 245 E-----HPSRKI------FRKSRISEEDDRSELD----DNNTMEEVKSDSTENSNSRDTG 289 Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEV 331 S+ D K D + + +S S VD SS +S + + L N + EEV Sbjct: 290 L--SQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEAN---LSSQENSSESQEEV 343 Query: 332 TQSQL----DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAE 387 D TS+ Q+ S+ S + S+ + +S SS + N + Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 403 Query: 388 DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPA---SDFDDSG 444 +S + +++ + S + +SEE E S + S D N S ++ G Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 463 Query: 445 SL 446 L Sbjct: 464 QL 465 >gi|16445033 ACRC protein [Homo sapiens] Length = 691 Score = 41.2 bits (95), Expect = 0.004 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 13/174 (7%) Query: 271 DTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEE 330 D + +EA D N + D S S V +D+S S D+S D S+ + + Sbjct: 160 DDNSDDSEAPDDNSDDSEAPDDNSDDSD---VPDDNSDDSSDDNS---DDSSDDNSDDSD 213 Query: 331 VTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSE-PRNGGTNEESNSSGNTNTDPPAEDS 389 V + D D S+V +S SE P + + E+ + +++ P + S Sbjct: 214 VPDDKSDDSDVPDDSSDDSDVPDD----SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 269 Query: 390 QKSSGANTSKDRPHASGTDGDESE--EDPPEHKPSKLKRSHELDIDENPASDFD 441 S + S D AS D+SE +D + + +S + D+ E+ + D D Sbjct: 270 DDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSD 323 Score = 33.5 bits (75), Expect = 0.86 Identities = 37/187 (19%), Positives = 65/187 (34%), Gaps = 22/187 (11%) Query: 263 DASQSCDTDTYTS----KTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEIL 318 D+ + C T + +DD++ E C + P PI++ +D + D D+ Sbjct: 82 DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEP--PIVISDDDN---DDDNG--- 133 Query: 319 DGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378 N EV D + D + SE + + + + NS Sbjct: 134 --------NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185 Query: 379 NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEED--PPEHKPSKLKRSHELDIDENP 436 + D ++DS + ++S D S D+S++ P + D E P Sbjct: 186 SDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP 245 Query: 437 ASDFDDS 443 DDS Sbjct: 246 DDSSDDS 252 Score = 32.0 bits (71), Expect = 2.5 Identities = 29/153 (18%), Positives = 54/153 (35%), Gaps = 9/153 (5%) Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322 D+ D +S +DD +D+ D+ S V +DSS D S++ D S Sbjct: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS-----DDSDVPDDSS 239 Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382 + E D + D SE + + + + +S + + Sbjct: 240 D----DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEAS 295 Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEED 415 D ++DS+ + D P D D +++ Sbjct: 296 DDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328 >gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] Length = 1161 Score = 40.4 bits (93), Expect = 0.007 Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 9/152 (5%) Query: 298 SPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKREC 357 +P DN S T ++ D + + +L + +DS ++ H S Sbjct: 625 NPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFI 684 Query: 358 PASGQSEPR--NGGTNEESNSSG---NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDES 412 SG E + + N+E+ ++ N T P ++D + +G TS G D ES Sbjct: 685 SHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQR--TGKKTSVQGQVQKGNDESES 742 Query: 413 --EEDPPEHKPSKLKRSHELDIDENPASDFDD 442 E DPP K S+ + + ++ + DF+D Sbjct: 743 DFESDPPSPKSSEEEEQDDEEVLQGEQGDFND 774 >gi|62750354 matrin 3 [Homo sapiens] Length = 847 Score = 40.4 bits (93), Expect = 0.007 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 6/79 (7%) Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGD-ESEEDPPEHKPSKLKRSH-E 429 +ES S + TD SQK+ + K++ SG DG+ ++++D E +P+ L S E Sbjct: 602 KESPSDKKSKTD----GSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDE 657 Query: 430 LDIDENPASDFDDSGSLLG 448 L +DE A+ +SGS +G Sbjct: 658 LLVDEEEAAALLESGSSVG 676 Score = 37.0 bits (84), Expect = 0.078 Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 20/167 (11%) Query: 278 EADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILD--GISNIKLNSEEVTQSQ 335 E D K+D+ + +++ ++VD + + + S + D ++N+ + + + Sbjct: 636 EKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEP 695 Query: 336 LDSCTSHDGH------QQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDS 389 D DG ++L +V E ++ NG NEE NT+P AE S Sbjct: 696 SDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEE-------NTEPGAESS 748 Query: 390 QKSSGANTSKDRPHASGTDGDESEED---PPEHKPSKLKRSHELDID 433 + + N KD + DE+++D P E++ + + + ID Sbjct: 749 ENADDPN--KDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGID 793 >gi|21626466 matrin 3 [Homo sapiens] Length = 847 Score = 40.4 bits (93), Expect = 0.007 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 6/79 (7%) Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGD-ESEEDPPEHKPSKLKRSH-E 429 +ES S + TD SQK+ + K++ SG DG+ ++++D E +P+ L S E Sbjct: 602 KESPSDKKSKTD----GSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDE 657 Query: 430 LDIDENPASDFDDSGSLLG 448 L +DE A+ +SGS +G Sbjct: 658 LLVDEEEAAALLESGSSVG 676 Score = 37.0 bits (84), Expect = 0.078 Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 20/167 (11%) Query: 278 EADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILD--GISNIKLNSEEVTQSQ 335 E D K+D+ + +++ ++VD + + + S + D ++N+ + + + Sbjct: 636 EKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEP 695 Query: 336 LDSCTSHDGH------QQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDS 389 D DG ++L +V E ++ NG NEE NT+P AE S Sbjct: 696 SDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEE-------NTEPGAESS 748 Query: 390 QKSSGANTSKDRPHASGTDGDESEED---PPEHKPSKLKRSHELDID 433 + + N KD + DE+++D P E++ + + + ID Sbjct: 749 ENADDPN--KDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGID 793 >gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [Homo sapiens] Length = 568 Score = 40.0 bits (92), Expect = 0.009 Identities = 58/294 (19%), Positives = 117/294 (39%), Gaps = 36/294 (12%) Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPE 418 +S S + ++ S+SS ++++ + S SS ++TS +PH + E Sbjct: 153 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKE------- 205 Query: 419 HKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGG---IPNFSHRQVRYLEKNV 475 KPSK R H+ E P+ D + S K + +P + ++ + + K Sbjct: 206 -KPSKDSREHKSAFKE-PSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEP 263 Query: 476 KLKSKYLDMRR-QIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKP------MDE 528 K S L + Q K +SE+ KK K S F ++ + P + Sbjct: 264 KPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSAD 323 Query: 529 EASQESSSHDNVHDASTSSD-SEEQDMSVKKGDDLLETNN---------------PEPEK 572 + + SH + S+ SE++ ++ DD+++ N+ P P Sbjct: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS 383 Query: 573 CQSVSSAGELETENYERDSLLATVPD-EQDCVTQEVPDSRQAETEAEVKKKKNK 625 S SS+ ++ ++ L + + D D +E + + ++E+++ N+ Sbjct: 384 SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNR 437 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 39.7 bits (91), Expect = 0.012 Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 20/181 (11%) Query: 352 SSKRECPA----SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASG- 406 S +R PA SG+ + GG++ + + + P Q+ +G S H S Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813 Query: 407 TDGDESEEDPPEHK-----PSKLKRSHELDIDENPASDFDDSGSLLGFKY----GSGQKY 457 + GDE +D H+ PS+ E +E+ S+ S S G ++ S + Y Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEE---EEDSGSEHSRSRSRSGRRHSSHRSSRRSY 870 Query: 458 GGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517 + S Q Y + Y D + + +K + +S+ + SK SK K Sbjct: 871 SSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKR---SHDSDDSDYASSKHRSKRHK 927 Query: 518 F 518 + Sbjct: 928 Y 928 Score = 36.6 bits (83), Expect = 0.10 Identities = 82/355 (23%), Positives = 137/355 (38%), Gaps = 33/355 (9%) Query: 296 PSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK- 354 P+ P ++ +S D D++ K S +S + + S + +SEVS + Sbjct: 406 PNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQP 465 Query: 355 RECPASGQSEPRNGGTNEESNSSGNTNTDPPAED-SQKSSG-----ANTSKDRPHASGTD 408 +E + SEP G E + G +D E SQK S +N+SK+ A+ Sbjct: 466 KETSMTEPSEP--GSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPA- 522 Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468 G ES+E P +H L DE+ A + S L+ K Y P + + Sbjct: 523 GKESQEGP-KHPTGPF--FPVLSKDESTALQWP-SELLIFTKAEPSISYSCNPLYFDFK- 577 Query: 469 RYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDE 528 L +N ++K + + I +K + +P KSK + EK + MD Sbjct: 578 --LSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEP--NKSKEVGG-EKIVRSSGGRMDA 632 Query: 529 EASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYE 588 AS + S N + S SE +D T P K + + + + Sbjct: 633 PASGSACSGLNKQEPGGSHGSETED-----------TGRSLPSKKERSGKSHRHKKKKKH 681 Query: 589 RDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPE 643 + S + D T+E ++ +++ +KK+ +KKNK E PE Sbjct: 682 KKSSKHKRKHKAD--TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPE 734 >gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo sapiens] Length = 1094 Score = 38.9 bits (89), Expect = 0.020 Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 20/187 (10%) Query: 257 AQGWT--FDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDH 314 A+ WT A Q + S++E ++ + + + S S ++ G S++D Sbjct: 657 AKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDS 716 Query: 315 SEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNG-GTNEE 373 SE S+ + +SE +S L++ + ++KR A G+S+ +G NE+ Sbjct: 717 SED----SSSEQDSESGRESGLEN-----------KRTAKRNSKAKGKSDSEDGEKENEK 761 Query: 374 SNSSGNTNTDPPA-EDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDI 432 S +S ++N + + EDS S + + + S E E+ + + K LD+ Sbjct: 762 SKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDL 821 Query: 433 DE-NPAS 438 D+ NP S Sbjct: 822 DDFNPVS 828 Score = 30.4 bits (67), Expect = 7.3 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 7/105 (6%) Query: 528 EEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENY 587 E + S+ D+ D+S+ DSE S + + N+ K + S + + E EN Sbjct: 705 ESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNS----KAKGKSDSEDGEKEN- 759 Query: 588 ERDSLLATVPDEQDCVTQEVPDSR-QAETEAEVKKKK-NKKKNKK 630 E+ + DE + DS ++E E+E + ++ K+K KK Sbjct: 760 EKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKK 804 Score = 30.0 bits (66), Expect = 9.5 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 17/142 (11%) Query: 50 DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109 DS + SG ++ E+ E G E DS ++S + ++E R GL + TA Sbjct: 691 DSESESGSESGEQGESG------EEGDSNEDSSEDSSSEQDSESGRESGLE---NKRTAK 741 Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE--EDDILASDDPSSIEQYENTR 167 + N++ K K + +K+ +S E ED S+ S E +R Sbjct: 742 R------NSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESR 795 Query: 168 TYELQSKKDTETENPPVENTLS 189 + +K T+ + P+ +S Sbjct: 796 RVTKEKEKKTKQDRTPLTKDVS 817 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 38.9 bits (89), Expect = 0.020 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 10/124 (8%) Query: 309 TSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNG 368 +S+KD + D + EE + DG + S+ SSK C S+ N Sbjct: 973 SSEKDEED--DEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSK--CSLYADSDGEND 1028 Query: 369 GTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSH 428 T++ +SS ++++ + S SS +++S+ + DE EE+ P PS Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSE------SSSEDEEEEERPAALPSASPPPR 1082 Query: 429 ELDI 432 E+ + Sbjct: 1083 EVPV 1086 Score = 34.7 bits (78), Expect = 0.39 Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 7/122 (5%) Query: 528 EEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVS-------SAG 580 EEASQESSS + D + E+++ +V E ++ E E+ S S S G Sbjct: 966 EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDG 1025 Query: 581 ELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAA 640 E ++ + S ++ + S +E+ +E ++++ + PP Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085 Query: 641 VP 642 VP Sbjct: 1086 VP 1087 >gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 38.9 bits (89), Expect = 0.020 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 17/156 (10%) Query: 89 SEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEE 148 SE + S P ++TA K EVS +K K + +KK ++ RK+ +E Sbjct: 26 SERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKK------EDKERKKKDE 77 Query: 149 DDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGG 208 + + A ++ E+ E + E + KK E E + +++ E+ + E Sbjct: 78 EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE---- 133 Query: 209 LLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQL 244 +W+ H + L S+ N PD++ E E +S+L Sbjct: 134 ----AWERHHLRKELRSKNQNAPDSRPE-ENFFSRL 164 >gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 38.9 bits (89), Expect = 0.020 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 17/156 (10%) Query: 89 SEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEE 148 SE + S P ++TA K EVS +K K + +KK ++ RK+ +E Sbjct: 26 SERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKK------EDKERKKKDE 77 Query: 149 DDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGG 208 + + A ++ E+ E + E + KK E E + +++ E+ + E Sbjct: 78 EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE---- 133 Query: 209 LLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQL 244 +W+ H + L S+ N PD++ E E +S+L Sbjct: 134 ----AWERHHLRKELRSKNQNAPDSRPE-ENFFSRL 164 >gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 38.9 bits (89), Expect = 0.020 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 22/156 (14%) Query: 473 KNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQ 532 K + KS L ++K KNK + K++EK L+K+ KF+ E ++ Sbjct: 349 KEINEKSNILS--NEMKAKNKDV---KDTEKK-------LNKITKFI---------EENK 387 Query: 533 ESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV-SSAGELETENYERDS 591 E + ++ D + KK + L+ + + E+ +S+ + + + E R++ Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNN 447 Query: 592 LLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKK 627 L ++++ +EV DS + ET+ K+K++++K Sbjct: 448 ALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483 >gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 38.9 bits (89), Expect = 0.020 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 22/156 (14%) Query: 473 KNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQ 532 K + KS L ++K KNK + K++EK L+K+ KF+ E ++ Sbjct: 349 KEINEKSNILS--NEMKAKNKDV---KDTEKK-------LNKITKFI---------EENK 387 Query: 533 ESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV-SSAGELETENYERDS 591 E + ++ D + KK + L+ + + E+ +S+ + + + E R++ Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNN 447 Query: 592 LLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKK 627 L ++++ +EV DS + ET+ K+K++++K Sbjct: 448 ALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 38.5 bits (88), Expect = 0.027 Identities = 38/166 (22%), Positives = 66/166 (39%), Gaps = 10/166 (6%) Query: 274 TSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNI--KLNSEEV 331 T+KT+ K +E F SSP+ + T + + ++ S I E+ Sbjct: 510 TTKTKMQSKINENIAAASSTPF-SSPVNLSTSGRRTPG-NQTPVMPSASPILHSQGKEKA 567 Query: 332 TQSQLDSC-TSHDGHQQLSEVSSKR----ECPASGQSEPRNGGTNEESNSSGNTNT-DPP 385 + ++ T H H S V R + P+S SE N E+ + D Sbjct: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE 627 Query: 386 AEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELD 431 ++DSQ S +N+ D + D D+ ++D + K S +L+ Sbjct: 628 SDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLN 673 Score = 32.0 bits (71), Expect = 2.5 Identities = 64/333 (19%), Positives = 132/333 (39%), Gaps = 56/333 (16%) Query: 307 SGTSDKDHSEILDGISNIKLNSE-EVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEP 365 +G+ + ++ + GI+ L++ + Q S +S G+++ ++ SK ++P Sbjct: 170 NGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSK--------NQP 221 Query: 366 RNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLK 425 + ++ + + +S SG ++ S +D D+ EED E S ++ Sbjct: 222 LDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQS-IE 280 Query: 426 RSHELDIDENPASDFDDSGSLLGFKYG-SGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDM 484 S + D D + + +L +G S K G Q + + + + L S+ Sbjct: 281 ESEDDDSDSESEAQHKSNNQVL--LHGISDPKADGQKATEKAQEKRIHQPLPLASE---- 334 Query: 485 RRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDAS 544 H F +++ K+ ++LS+ F+ +A +ES + S Sbjct: 335 ------SQTHSFQSQQ------KQPQVLSQQLPFIF-----QSSQAKEESVNKHTSVIQS 377 Query: 545 TSSDSEEQDMSV---KKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQD 601 T S + +S+ K + ++ P P+ V AG T +E Sbjct: 378 TGLVSNVKPLSLVNQAKKETYMKLIVPSPD----VLKAGNKNTS------------EESS 421 Query: 602 CVTQEVPDSRQAETEA---EVKKKKNKKKNKKV 631 +T E+ R+ +A ++KK+++ K KKV Sbjct: 422 LLTSELRSKREQYKQAFPSQLKKQESSKSLKKV 454 Score = 30.8 bits (68), Expect = 5.6 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 19/172 (11%) Query: 239 QHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSS 298 QH+S +EQF+ ++ + S+ + D E D+++DE D S Sbjct: 578 QHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQS---- 633 Query: 299 PIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECP 358 ++DS+ SD + SE D + S+ T+ + S +L++ +S + P Sbjct: 634 ----ESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTS-------MKLNKTTSSVKSP 682 Query: 359 A---SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGT 407 + +G S PRN + S+ + + ++T PH SGT Sbjct: 683 SMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPH-SGT 733 >gi|24415404 MDN1, midasin homolog [Homo sapiens] Length = 5596 Score = 37.7 bits (86), Expect = 0.046 Identities = 41/179 (22%), Positives = 72/179 (40%), Gaps = 13/179 (7%) Query: 269 DTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNS 328 + D + DD +E + D + + P M + DS + D+ LD ++ K S Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDN---LDSGNSNKDKS 4826 Query: 329 EEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAED 388 ++ + + + + DG Q +++ Q + R+ NE GN P E Sbjct: 4827 QQDKKEEKEEAEADDGGQGEDKINE--------QIDERDYDENEVDPYHGNQEKVPEPEA 4878 Query: 389 SQKSSGANT-SKDRPHASGTDGDESEEDPP-EHKPSKLKRSHELDIDENPASDFDDSGS 445 N S+D+ TD +E EE+ P E K + HE + +D ++S S Sbjct: 4879 LDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQS 4937 Score = 37.4 bits (85), Expect = 0.059 Identities = 70/378 (18%), Positives = 129/378 (34%), Gaps = 59/378 (15%) Query: 261 TFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVS-FPSSPIMVDNDSSGTSDKDHSEILD 319 TF Q D + SK++ +++ M D + + SD + ++ Sbjct: 4702 TFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDK 4761 Query: 320 GISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESN-SSG 378 + + LN EE + D + E +K E G E + ++ N SG Sbjct: 4762 HMGD--LNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSG 4819 Query: 379 NTNTDPPAEDSQKSS--------GANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHEL 430 N+N D +D ++ G K D DE+E DP K+ L Sbjct: 4820 NSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL 4879 Query: 431 DIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKM 490 D+ ++ D +D K GG + + E +++K K + + + Sbjct: 4880 DLPDDLNLDSED-------------KNGG--EDTDNEEGEEENPLEIKEKPEEAGHEAEE 4924 Query: 491 KNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSE 550 + + ES+ P +P EE E + + T +D + Sbjct: 4925 RGETETDQNESQSP------------------QEP--EEGPSEDDKAEGEEEMDTGADDQ 4964 Query: 551 EQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDS 610 + D + +PE + S E + E E P +Q QE + Sbjct: 4965 DGDAA----------QHPEEHSEEQQQSVEEKDKEADEEGG--ENGPADQGFQPQEEEER 5012 Query: 611 RQAETEAEVKKKKNKKKN 628 ++TE +V + +K++ Sbjct: 5013 EDSDTEEQVPEALERKEH 5030 >gi|110349756 zygin 2 isoform 2 [Homo sapiens] Length = 380 Score = 37.7 bits (86), Expect = 0.046 Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 24/164 (14%) Query: 483 DMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEA-------SQESS 535 ++R Q+ M + I + +++P F +++ ++E+ + P D+E S S Sbjct: 139 ELREQLDMHS--IIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQ 196 Query: 536 SHDNVHDASTSSDSEE-QDMSVKKGDDLLE-----TNNPEPEKCQSVSSAGELETENYER 589 + +ST S E + +SV + +++LE E Q ++ ELE E + Sbjct: 197 EIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVK 256 Query: 590 DSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG 633 +S ++ + + Q ++Q E + KKKK K NG Sbjct: 257 NSFISVLIEVQ---------NKQKEHKETAKKKKKLKNGSSQNG 291 >gi|110349754 zygin 2 isoform 1 [Homo sapiens] Length = 353 Score = 37.7 bits (86), Expect = 0.046 Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 24/164 (14%) Query: 483 DMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEA-------SQESS 535 ++R Q+ M + I + +++P F +++ ++E+ + P D+E S S Sbjct: 139 ELREQLDMHS--IIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQ 196 Query: 536 SHDNVHDASTSSDSEE-QDMSVKKGDDLLE-----TNNPEPEKCQSVSSAGELETENYER 589 + +ST S E + +SV + +++LE E Q ++ ELE E + Sbjct: 197 EIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVK 256 Query: 590 DSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG 633 +S ++ + + Q ++Q E + KKKK K NG Sbjct: 257 NSFISVLIEVQ---------NKQKEHKETAKKKKKLKNGSSQNG 291 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,248,358 Number of Sequences: 37866 Number of extensions: 1726206 Number of successful extensions: 8887 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 334 Number of HSP's that attempted gapping in prelim test: 7521 Number of HSP's gapped (non-prelim): 1488 length of query: 853 length of database: 18,247,518 effective HSP length: 111 effective length of query: 742 effective length of database: 14,044,392 effective search space: 10420938864 effective search space used: 10420938864 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.