Guide to the Human Genome
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Search of human proteins with 151301096

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151301096 trimethylguanosine synthase homolog [Homo sapiens]
         (853 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151301096 trimethylguanosine synthase homolog [Homo sapiens]      1746   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    60   7e-09
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    57   9e-08
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    48   3e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    48   3e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    47   6e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           47   8e-05
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         45   2e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               43   0.001
gi|125656165 THO complex 2 [Homo sapiens]                              42   0.002
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                42   0.002
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 42   0.002
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    41   0.004
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    41   0.004
gi|16445033 ACRC protein [Homo sapiens]                                41   0.004
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            40   0.007
gi|62750354 matrin 3 [Homo sapiens]                                    40   0.007
gi|21626466 matrin 3 [Homo sapiens]                                    40   0.007
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    40   0.009
gi|50962882 G patch domain containing 8 [Homo sapiens]                 40   0.012
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    39   0.020
gi|55741677 SET domain containing 1A [Homo sapiens]                    39   0.020
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    39   0.020
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    39   0.020
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.020
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    39   0.020
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    39   0.027
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       38   0.046
gi|110349756 zygin 2 isoform 2 [Homo sapiens]                          38   0.046
gi|110349754 zygin 2 isoform 1 [Homo sapiens]                          38   0.046

>gi|151301096 trimethylguanosine synthase homolog [Homo sapiens]
          Length = 853

 Score = 1746 bits (4523), Expect = 0.0
 Identities = 853/853 (100%), Positives = 853/853 (100%)

Query: 1   MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT 60
           MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT
Sbjct: 1   MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQAT 60

Query: 61  EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN 120
           EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN
Sbjct: 61  EEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRN 120

Query: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180
           KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE
Sbjct: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180

Query: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH 240
           NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH
Sbjct: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQH 240

Query: 241 YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI 300
           YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI
Sbjct: 241 YSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPI 300

Query: 301 MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS 360
           MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS
Sbjct: 301 MVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPAS 360

Query: 361 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420
           GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK
Sbjct: 361 GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420

Query: 421 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480
           PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK
Sbjct: 421 PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480

Query: 481 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540
           YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV
Sbjct: 481 YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540

Query: 541 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600
           HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ
Sbjct: 541 HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600

Query: 601 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD 660
           DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD
Sbjct: 601 DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDD 660

Query: 661 GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI 720
           GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI
Sbjct: 661 GIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDI 720

Query: 721 DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR 780
           DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR
Sbjct: 721 DPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIR 780

Query: 781 TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA 840
           TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA
Sbjct: 781 TMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITA 840

Query: 841 YFGDLIRRPASET 853
           YFGDLIRRPASET
Sbjct: 841 YFGDLIRRPASET 853


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 74/372 (19%), Positives = 132/372 (35%), Gaps = 12/372 (3%)

Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
           D+S S D+D+  S + +D  + +     D     SS     +DSS +SD   S      S
Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSS-DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620

Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
           + K +S   ++S+ DS  S D     S+ +S      S  S+  N   + +S+ S +++ 
Sbjct: 621 DSKSDS---SKSESDSSDS-DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
              + DS  SS ++ S D  ++S +       D      S    S+  D D + +SD  D
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 443 SGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESE 502
           S +       S        + S       + +    S   D        + +        
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS--DSSDSSNSSDSNDSSNSSDS 794

Query: 503 KPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDL 562
                 S   +  +   +  +   D   S +SS+  +  D+S SSDS +   S   G D 
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS-SDGSDS 853

Query: 563 LETNNPEPEKCQSVSSAGELETENYERDSL----LATVPDEQDCVTQEVPDSRQAETEAE 618
             +N  +       S + +    +   DS      +   D  D       DS  +   ++
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 619 VKKKKNKKKNKK 630
                N   + +
Sbjct: 914 SSDSSNSSDSSE 925



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 64/329 (19%), Positives = 116/329 (35%), Gaps = 28/329 (8%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S D+   ++ ++++D ++         S  SS     +DSS +SD D S   D  +
Sbjct: 769  DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828

Query: 323  NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
            +   +    +    DS  S DG           +  +S +S+  N   + +S+ S N++ 
Sbjct: 829  SSDSSDSSNSSDSSDSSDSSDG----------SDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 383  DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
               + DS +SS ++ S D  ++S +D  +S         S    S E     + ++  D 
Sbjct: 879  SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938

Query: 443  SGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESE 502
            S                  N S         N    S   D        + +   + +S 
Sbjct: 939  S------------------NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 503  KPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDL 562
                      S      +  +   D   S +SS   N  D+S SSDS     S    D  
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 563  LETNNPEPEKCQSVSSAGELETENYERDS 591
              +++ +       S++ +    +   DS
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 41/182 (22%), Positives = 70/182 (38%), Gaps = 1/182 (0%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321
            D+S S D+   +  +++ D +D         S  SS     +DSS +SD  D S+  D  
Sbjct: 993  DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 322  SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381
             +   +    +    DS  S D         S     +S  S+  +   + +S+ S +++
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112

Query: 382  TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
                + DS  SS ++ S D   +S +       D  E   S          D + +SD  
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 442  DS 443
            DS
Sbjct: 1173 DS 1174



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 4/185 (2%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S D+   +  +++ D +D         S  SS     +DSS +SD   S      S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 323  NIKLNSEEVTQS----QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378
            N   +S+    S      DS  S D     +   S     +S  S+  N   + +S+ S 
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151

Query: 379  NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPAS 438
            +++    + DS  SS ++ S D   +S +       D  +   S          D + +S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211

Query: 439  DFDDS 443
            D  DS
Sbjct: 1212 DSSDS 1216



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 60/300 (20%), Positives = 102/300 (34%), Gaps = 19/300 (6%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321
            D+S S D+   +  +++ D +D         S  SS     +DSS +SD  D S+  D  
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 322  SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381
             + + +    + +  DS  S D         S     +S  S   +   + +S+ S +++
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139

Query: 382  TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
                + DS +SS ++ S D   +S +       D  +   S          D + +SD  
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 442  DSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKES 501
            DS         S        + S       + N    S                  +  S
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS------------------SDSS 1241

Query: 502  EKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDD 561
            +      S   S         +   DE  SQ  S + N + + + SDSE  D +    DD
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 1/181 (0%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S D+D+ +  + + D +D         S  SS     +DSS +SD   S      S
Sbjct: 896  DSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954

Query: 323  NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
            +   +S+    S      S D     +   S     +S  S+  +   + +S+ S +++ 
Sbjct: 955  DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014

Query: 383  DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
               + DS  SS ++ S D   +S +       D  +   S          D + +SD  D
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074

Query: 443  S 443
            S
Sbjct: 1075 S 1075



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 2/181 (1%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S D+   +  +++ D +D         S  SS     +DSS +SD  +S      S
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 323  NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
            +   +S+    S  DS  S +         S     +S  S+  +   + +S+ S N++ 
Sbjct: 1038 DSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095

Query: 383  DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
               + DS  SS ++ S D   +S +       D  +   S    +     D + +SD  D
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155

Query: 443  S 443
            S
Sbjct: 1156 S 1156



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S D+   ++ +++ + +D         S  SS     +DSS +SD  +S      S
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 323  NIKLNSEEVTQS-QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381
            +   +S+    S   DS  S D     +   S     +S  S+  +   + +S+ S N++
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124

Query: 382  TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
                + DS  SS ++ S D   +S +       D  +   S          D + +SD  
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 442  DS 443
            DS
Sbjct: 1185 DS 1186



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/195 (23%), Positives = 72/195 (36%), Gaps = 10/195 (5%)

Query: 261 TFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDG 320
           T D + S       +  + +DK+D    K D     SS     +DSS +SD D S+    
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577

Query: 321 ISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSS--- 377
             +   +S+    S  DS  S +         S     +S  S+ ++  +  ES+SS   
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637

Query: 378 -------GNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHEL 430
                   N++      DS  SS ++ S D   +S +    S  D      S        
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697

Query: 431 DIDENPASDFDDSGS 445
             + + +SD  DS S
Sbjct: 698 SSESSDSSDSSDSDS 712



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 40/184 (21%), Positives = 72/184 (39%), Gaps = 5/184 (2%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD-KDHSEILDGI 321
            D+S S D+    S   +D  N          S  SS     +DSS +SD  D S+  D  
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSD----SSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016

Query: 322  SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTN 381
            ++   ++   + +  DS  S D         S     +S  S+  +   + +S+ S +++
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076

Query: 382  TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
                + +S  SS ++ S D   +S +       D  +   S    +     D + +SD  
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 442  DSGS 445
            DS +
Sbjct: 1137 DSSN 1140



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 8/195 (4%)

Query: 257  AQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSE 316
            + G   D+S   D+   +  +++ D ++         S  SS     +DSS +SD D S+
Sbjct: 848  SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907

Query: 317  ILDGI-SNIKLNSEEVTQSQLDSCTSHDGHQQLSEVS-----SKRECPASGQSEPRNGGT 370
              +   S+   NS + ++S   S  S+      S  S     S     +S  S+  N   
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967

Query: 371  NEESNSSGNTNTDPPAE--DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSH 428
            + +SNSS ++++   ++  DS  SS ++ S D  ++S +       D      S      
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027

Query: 429  ELDIDENPASDFDDS 443
                D + +SD  DS
Sbjct: 1028 SNSSDSSDSSDSSDS 1042



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 39/183 (21%), Positives = 73/183 (39%), Gaps = 3/183 (1%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            D+S S ++   +  + + D ++         S  SS     +DSS +SD  +S   D   
Sbjct: 913  DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS--DSSD 970

Query: 323  NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
            +   +S + + S  DS  S D         S     +S  S+  +   + +S++S +++ 
Sbjct: 971  SNSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 383  DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
               + DS  SS ++ S D   +S +       D  +   S          D + +SD  D
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089

Query: 443  SGS 445
            S +
Sbjct: 1090 SSN 1092



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 4/185 (2%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSD----KDHSEIL 318
            D+S S D+   +  +++ + +D         S  SS     +DSS +SD     D S+  
Sbjct: 984  DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043

Query: 319  DGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378
            D   +   +    +    DS  S D         S     +S  S+  N   + +S+ S 
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103

Query: 379  NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPAS 438
            +++    + DS  SS ++ S D   +S +       +  +   S          D + +S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163

Query: 439  DFDDS 443
            D  DS
Sbjct: 1164 DSSDS 1168



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 43/189 (22%), Positives = 70/189 (37%), Gaps = 16/189 (8%)

Query: 263  DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
            ++S S D    +  + + D +D         S  SS     +DSS +SD   S   D  S
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSD------SSNSSDSSNSSDSSNSSDSSDSNSSD--S 976

Query: 323  NIKLNSEEVTQS--------QLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEES 374
            +   NS + + S          DS  S D         S     +S  S+  N   + +S
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036

Query: 375  NSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDE 434
            + S +++    + DS  SS ++ S D   +S +       D  +   S          D 
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096

Query: 435  NPASDFDDS 443
            + +SD  DS
Sbjct: 1097 SDSSDSSDS 1105



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 11/183 (6%)

Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
           DA+   D ++ +S+ +A   +DE     D  +   S    D+DS  TSD ++S   D   
Sbjct: 476 DANSESDNNS-SSRGDASYNSDES---KDNGNGSDSKGAEDDDSDSTSDTNNS---DSNG 528

Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
           N    +++  +S      S       S+ S+  +   S  S+  +  ++ +S+SS + ++
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588

Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDD 442
           D    DS  SS ++ S D    S    D S+        S   +S     D +  SD  D
Sbjct: 589 DSSDSDSSDSSNSSDSSD----SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644

Query: 443 SGS 445
           S S
Sbjct: 645 SNS 647



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 72/385 (18%), Positives = 131/385 (34%), Gaps = 40/385 (10%)

Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIM--VDNDSSGTSDKDHSEILDGISNIKLNSE 329
           T  S+T A  K+ +K +++   S  +  I   V   + G  DK    ++ G  N+K   E
Sbjct: 360 TKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGE 419

Query: 330 ---------------EVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNE-- 372
                          +V  S   S ++ DG+          +      S+  NG  +   
Sbjct: 420 VVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANS 479

Query: 373 -----------------ESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEED 415
                            ES  +GN +    AED    S ++T+    + +G +G++ + D
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND-DND 538

Query: 416 PPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNV 475
             +    K   S     D + +SD  DS         S        + S         + 
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598

Query: 476 KLKSKYLDMRRQIKMKNKHIFFTKESE--KPFFKKSKILSKVEKFLTWVNKPMDEEASQE 533
              S   D        +       +S+  K     S   SK +   +  +   D   S +
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658

Query: 534 SSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLL 593
           SS+  N  D+S SSDS +   S     +  ++++       S SS     +++   DS  
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSS-SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717

Query: 594 ATVPDEQDCVTQEVPDSRQAETEAE 618
           ++  +  D  +    DS  +   ++
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSD 742



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 22/180 (12%)

Query: 320 GISNIKLNSEEVTQSQLDSCTSHDGHQQLS-EVSSKRECPASGQSEPRNGGTNEESNSSG 378
           G +N   N +E+ ++   SC +     +++ +++SKR      +  P  G      NS G
Sbjct: 188 GSNNSTDNEDEIIEN---SCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDG 244

Query: 379 NTNTDPPAEDSQKSSG------ANTSKDRPHAS----GTD-GDESEEDPPEHKPSKLKRS 427
           + + +   ED  + SG      A   KD  + S    G D G E + D    + S  K  
Sbjct: 245 SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEY 304

Query: 428 HELDIDENPASDFDDSGSLLGFKYGSG-------QKYGGIPNFSHRQVRYLEKNVKLKSK 480
           ++ +  E+P ++ D   +    +  +G       Q+       +HR+ + +E  +  +S+
Sbjct: 305 YDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESE 364



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 524 KPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELE 583
           K   + +  +SS   N  D+S SSDS+  D +     D  ++++ +     S  S+   +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603

Query: 584 TENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKN 624
           + +    S  +   D  D  +    DS ++E+++     K+
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKS----DSSKSESDSSDSDSKS 640


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 75/292 (25%), Positives = 133/292 (45%), Gaps = 16/292 (5%)

Query: 346 QQLSEVSSKRECPASGQSEPRNGGTNEES-NSSGNTNTDPPAEDSQKSSGANTSKDRPHA 404
           +Q+ E  +KR+  A  ++  ++   NE+S  S  ++ T+P +++S+  S   + KD+  +
Sbjct: 145 KQIVEEKTKRQNEAD-KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDS 203

Query: 405 SGTDGDESEEDPPEHKPSK-LKRSHELDIDENPASDFDDSGSL-LGFKYGSGQKYGGIPN 462
             +    +E    ++ P K LKRS       +P S+     SL + F    GQ      N
Sbjct: 204 KNSKKTNTEFLHTKNNPKKDLKRS---KTSNDPISEICSENSLNVDFLMLVGQSDDESIN 260

Query: 463 FSHRQVRYLEKNVKLKS-KYLDMRRQIKMKNKHIFFTKESE--KPFFKKSKILSKVEKFL 519
           F      Y + N K  S KY    ++   KN       ESE  K   K SK   KV+K +
Sbjct: 261 FDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSK---KVKKNV 317

Query: 520 TWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSA 579
              +K  D +   ES+  ++        D+++    +KK DD  +     PE   + S  
Sbjct: 318 KKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK-DDKKKDTKKYPESTDTESGD 376

Query: 580 GELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKK-KKNKKKNKK 630
            + +  N  R+   A+  D++    +++  S  +E+E E K+ +K++KK+KK
Sbjct: 377 AK-DARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKK 427



 Score = 33.9 bits (76), Expect = 0.66
 Identities = 56/266 (21%), Positives = 96/266 (36%), Gaps = 26/266 (9%)

Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELD 431
           E   S       P  +DS+K  G+  +      S    +E  +   E   + LK SHE +
Sbjct: 114 EYKKSKDEKGGTPLKKDSKKKGGSYATNPE---SKQIVEEKTKRQNEADKTPLKSSHENE 170

Query: 432 IDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMK 491
             +   S  + +      K  S        N S +  +  + + K  +++L  +   K  
Sbjct: 171 QSKKSKSSSETNPESQNSKTVS-------KNCSQKDKKDSKNSKKTNTEFLHTKNNPKKD 223

Query: 492 NKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDE----EASQESSSHDNVHDAS--- 544
            K    +K S  P  +     S    FL  V +  DE    +A   + S +N  + S   
Sbjct: 224 LKR---SKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280

Query: 545 TSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVT 604
           T    ++   + KK  D       E E  +      +   +N ++D     V  + +   
Sbjct: 281 TKYTKKDTKKNAKKSSDA------ESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTD 334

Query: 605 QEVPDSRQAETEAEVKKKKNKKKNKK 630
            E  DS+    + +  KKK KK +KK
Sbjct: 335 AESGDSKDERKDTKKDKKKLKKDDKK 360


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 71/347 (20%), Positives = 133/347 (38%), Gaps = 40/347 (11%)

Query: 297  SSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRE 356
            S P+ VD+D      ++       +  IK N            +  DG         K+ 
Sbjct: 1215 SVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS----------SDEDGSSDDEPEEGKKR 1264

Query: 357  CPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANT--SKDRPHASGTDGDESEE 414
               +G+    N G +EE+ +  N+ +D  +E+S+K    +         + G  G+E + 
Sbjct: 1265 ---TGKQNEENPG-DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1320

Query: 415  DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474
             P EHK  K +   ++  +++  SDF +SG          ++     +    ++   +++
Sbjct: 1321 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1380

Query: 475  VKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQES 534
             K K K    RR+IK+        +E      K +    + EK      +  +EE  +E 
Sbjct: 1381 YKQKKK----RRRIKV--------QEDSSSENKSNSEEEEEEK-----EEEEEEEEEEEE 1423

Query: 535  SSHDNVHDASTSSDSEEQDMSVKKGDDL-LETNNPEPEKCQSVSSAGELETENYERDSLL 593
               D   D+ +     ++   + K D L  ET N   E+ +      E E E  +   ++
Sbjct: 1424 EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVI 1483

Query: 594  A---TVPDEQDCVTQEVPDSRQAETEAEVKKKKN---KKKNKKVNGL 634
                  P +    T+ V D  +   E  V+  +N   K K  +V+G+
Sbjct: 1484 EIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1530



 Score = 30.0 bits (66), Expect = 9.5
 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 7/98 (7%)

Query: 326 LNSEEVTQSQLDSCTS--HDGHQQLSEVSSKRECP---ASGQSEPRNGGTNEESNSSGNT 380
           + +E +++S+L++     HD     SE S +   P   A  Q+  +  G+   S+   N+
Sbjct: 1   MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60

Query: 381 NTD-PPAEDSQKSSGANTSKDRPHASGTDGDESEEDPP 417
             +   + +  KSSG++ SK +P +  T   ES+++ P
Sbjct: 61  KEEGTSSSEKSKSSGSSRSKRKP-SIVTKYVESDDEKP 97


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 71/347 (20%), Positives = 133/347 (38%), Gaps = 40/347 (11%)

Query: 297  SSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRE 356
            S P+ VD+D      ++       +  IK N            +  DG         K+ 
Sbjct: 1253 SVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS----------SDEDGSSDDEPEEGKKR 1302

Query: 357  CPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANT--SKDRPHASGTDGDESEE 414
               +G+    N G +EE+ +  N+ +D  +E+S+K    +         + G  G+E + 
Sbjct: 1303 ---TGKQNEENPG-DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1358

Query: 415  DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474
             P EHK  K +   ++  +++  SDF +SG          ++     +    ++   +++
Sbjct: 1359 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1418

Query: 475  VKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQES 534
             K K K    RR+IK+        +E      K +    + EK      +  +EE  +E 
Sbjct: 1419 YKQKKK----RRRIKV--------QEDSSSENKSNSEEEEEEK-----EEEEEEEEEEEE 1461

Query: 535  SSHDNVHDASTSSDSEEQDMSVKKGDDL-LETNNPEPEKCQSVSSAGELETENYERDSLL 593
               D   D+ +     ++   + K D L  ET N   E+ +      E E E  +   ++
Sbjct: 1462 EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVI 1521

Query: 594  A---TVPDEQDCVTQEVPDSRQAETEAEVKKKKN---KKKNKKVNGL 634
                  P +    T+ V D  +   E  V+  +N   K K  +V+G+
Sbjct: 1522 EIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1568



 Score = 30.0 bits (66), Expect = 9.5
 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 7/98 (7%)

Query: 326 LNSEEVTQSQLDSCTS--HDGHQQLSEVSSKRECP---ASGQSEPRNGGTNEESNSSGNT 380
           + +E +++S+L++     HD     SE S +   P   A  Q+  +  G+   S+   N+
Sbjct: 1   MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60

Query: 381 NTD-PPAEDSQKSSGANTSKDRPHASGTDGDESEEDPP 417
             +   + +  KSSG++ SK +P +  T   ES+++ P
Sbjct: 61  KEEGTSSSEKSKSSGSSRSKRKP-SIVTKYVESDDEKP 97


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 81/379 (21%), Positives = 148/379 (39%), Gaps = 55/379 (14%)

Query: 256 EAQGWTFDASQSCDTDTYTSKTEADDKNDEKC-MKVDLVSFPSSPIMVDNDSSGTSDKDH 314
           EAQG   D        T  ++ E   K+ +K   K    SF       DNDS    DKD 
Sbjct: 68  EAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFD------DNDSEELEDKDS 121

Query: 315 SEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEES 374
                        S++  + +++  +  D     +++  K +  A   ++  +G   +E 
Sbjct: 122 K------------SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169

Query: 375 NSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDE 434
           NS                      + R ++SG  GDES+E     K  K  + ++   + 
Sbjct: 170 NSK-----------------KIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212

Query: 435 NPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKH 494
              ++ DD+     FK  +  +         R+ R  E   K K + L  + +++   K 
Sbjct: 213 ESGNEDDDA----SFKIKTVAQKKAEKKERERKKRDEE---KAKLRKLKEKEELETGKKD 265

Query: 495 IFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDM 554
               KES++  F++  + SKV    T V    +E+A   +++ D+        D +++D 
Sbjct: 266 QSKQKESQRK-FEEETVKSKV-TVDTGVIPASEEKAETPTAAEDD-----NEGDKKKKDK 318

Query: 555 SVKKGDDLLETNNPEPEKCQS---VSSAGELETENYERDSLLATVPDEQDCVTQEVPDSR 611
             KKG+   E    E +K  S   V +  E   +  E +       +E+    +E+   R
Sbjct: 319 KKKKGEK--EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376

Query: 612 QAETEAEVKKKKNKKKNKK 630
           + E   E +K++ KK+ +K
Sbjct: 377 KEEERLEQEKRERKKQKEK 395



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 52/277 (18%), Positives = 103/277 (37%), Gaps = 39/277 (14%)

Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468
           G   E++P + K  K K   + D DE+      +  SL      + ++   +    + + 
Sbjct: 30  GAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEE 89

Query: 469 RYLEKNVKLKSKY----------------LDMRRQIKMKNKHIFFTKESEKPFFKK--SK 510
            +  K+ K K +                  D + +   K K   ++   +   F K   K
Sbjct: 90  EFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK 149

Query: 511 ILSKVEKF-LTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPE 569
              K +K    W     DE+ S++      ++ +  S D  ++ +  +KG    + N P 
Sbjct: 150 AKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPG 209

Query: 570 PE--------------KCQSVSSAGELETENYERD---SLLATVPDEQDCVTQEVPDSRQ 612
           P               K  +   A + E E  +RD   + L  + ++++  T +   S+Q
Sbjct: 210 PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQ 269

Query: 613 AETEAEVKKKKNKKKNKKVNGLPP---EIAAVPELAK 646
            E++ + +++  K K     G+ P   E A  P  A+
Sbjct: 270 KESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 105/555 (18%), Positives = 205/555 (36%), Gaps = 88/555 (15%)

Query: 121 KVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETE 180
           K K KKKK +KK           ++++EDDIL   +  S+E        E  + K   TE
Sbjct: 39  KSKGKKKKEKKK-----------QDFDEDDILKELEELSLEAQGIKADRETVAVK--PTE 85

Query: 181 NPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSS-EPWNFPDTKEEWEQ 239
           N   E T   K +  +K +K   +       +    K    A    E ++  D  +++ +
Sbjct: 86  NNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNK 145

Query: 240 HYSQLYWYYLEQFQYWEAQGWTFDASQSC-DTDTYTSKTEADDKNDE-----KCMKVDLV 293
              +      +  + W+      D S+   +     S  E+ D++DE     K  K +  
Sbjct: 146 LPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQK 205

Query: 294 SFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSS 353
           + P       N  SG  D D S  +  ++  K   +E  + + D     +   +L ++  
Sbjct: 206 NKPG-----PNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD-----EEKAKLRKLKE 255

Query: 354 KRECPA-----SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTD 408
           K E        S Q E +     E   S    +T       +K+     ++D       +
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAED-----DNE 310

Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468
           GD+ ++D  + K  K ++  E     + A+      +L   K               RQ 
Sbjct: 311 GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK-----------EEEERQK 359

Query: 469 RYLEKNVK---------LKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK-- 517
           R  E+ +K          + + L+  ++ + K K     KE ++   K+ K+L+K ++  
Sbjct: 360 REEEERIKRLEELEAKRKEEERLEQEKRERKKQKE----KERKERLKKEGKLLTKSQREA 415

Query: 518 -----------FLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQD----MSVKKGDDL 562
                          V  P  +   ++   +++          E ++    M +    ++
Sbjct: 416 RARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEV 475

Query: 563 LETNNPEPEKC-QSVSSAGELETENYERDSLLATVPDEQ------DCVTQEVPDSRQAET 615
           +E   PE E+    V    E +TE+   D   A   DE+      + V  EV ++ + E 
Sbjct: 476 MEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEE 535

Query: 616 EAEVKKKKNKKKNKK 630
           E E +++++++  ++
Sbjct: 536 EEEEEEEEDEESEEE 550


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 33/191 (17%)

Query: 472  EKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEAS 531
            E+ + ++   LD++ +     K    TK+ +K   K+ K+ +K+ + +    K  +EE+ 
Sbjct: 2108 ERRLSIEQSKLDIK-EWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166

Query: 532  QESSSHDNVHDASTSSDSEEQDM------------SVKKGD------------------- 560
                  + + D       EE+++              K+GD                   
Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF 2226

Query: 561  -DLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEV 619
             + +E+   E EK +S+SS  E E E  E         +E++   +E  + +Q E E E 
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286

Query: 620  KKKKNKKKNKK 630
            KKKK K+K K+
Sbjct: 2287 KKKKKKEKKKE 2297


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 75/387 (19%), Positives = 139/387 (35%), Gaps = 45/387 (11%)

Query: 48  IRDSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRIT 107
           + ++GN   D   EE         A   + K I +  S+ + E E               
Sbjct: 319 LEETGNQHNDVEIEE---------AGEEEEKEIAIVHSDAEKEQEEEEQK---------- 359

Query: 108 AHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQ-----ESWRKEYEEDDILASDDPSSIEQ 162
             ++ EV M    +V+ + +K Q    +E++      E+ +    + +++ ++   S+E 
Sbjct: 360 --QEMEVKMEEETEVR-ESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEP 416

Query: 163 YENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQA 222
            EN  + EL+ + + E E      +LSP  E         N     +  +S +++     
Sbjct: 417 SENEASKELEPEMEFEIEPDKECKSLSPGKE---------NVSALDMEKESEEKEEKESE 467

Query: 223 LSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDK 282
              EP   P  + + +          L+     + +  +    Q     T        ++
Sbjct: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPER 527

Query: 283 NDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSH 342
            D     V L   P  P++  +  S +  K  S       N    S   + S   S +S 
Sbjct: 528 KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSS- 586

Query: 343 DGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRP 402
                 S  SS     +SG S  R+  ++  S++SG+++ D  +  S  S   + S+ R 
Sbjct: 587 ------STSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRG 639

Query: 403 HASGTDGDESEEDPPEHKPSKLKRSHE 429
           H        S  D      S L+RSH+
Sbjct: 640 HNRDRKHRRS-VDRKRRDTSGLERSHK 665



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 37/181 (20%), Positives = 78/181 (43%), Gaps = 23/181 (12%)

Query: 463 FSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWV 522
           F  R++ + E+  K++++    RRQ   + +H     E +K   ++ K+  +        
Sbjct: 267 FEGRRIEFAEQINKMEAR---PRRQSMKEKEHQVVRNEEQKAEQEEGKVAQR-------- 315

Query: 523 NKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGEL 582
               +EE  +  + H++V +   + + EE+++++   D   E    E E+ Q +    E 
Sbjct: 316 ----EEELEETGNQHNDV-EIEEAGEEEEKEIAIVHSD--AEKEQEEEEQKQEMEVKMEE 368

Query: 583 ETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKK-----NKKKNKKVNGLPPE 637
           ETE  E +    + P+E   V + V + +    + EV +          +N+    L PE
Sbjct: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPE 428

Query: 638 I 638
           +
Sbjct: 429 M 429


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 70/383 (18%), Positives = 140/383 (36%), Gaps = 28/383 (7%)

Query: 276 KTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQ 335
           K+ A D   E  +K  +    S        S   +++     +    + +L   +V+ S+
Sbjct: 166 KSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE 225

Query: 336 LDSCTSHDGHQQLSEVSSK-RECPASGQSEPRNGGTNEESNS------SGNTNTDPPAED 388
            +    H      +E   K R   +  +  PR+  ++ E+        S + + DPP   
Sbjct: 226 SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPR-- 283

Query: 389 SQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLG 448
           +Q S   N    +P  S ++ +  ++ P     ++    H+   + +  SD ++ G    
Sbjct: 284 NQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTE 343

Query: 449 FKYGSGQKYGGIPNFS-HRQVRYLEKNVKLK------SKYLDMRRQIKMKNKHIFFTKES 501
            +  S      +     H      E++ K K       K  +  +  K K   +  +++ 
Sbjct: 344 MQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDE 403

Query: 502 EKPFFKKSKILSKVE------------KFLTWVNKPMDEEASQESSSHDNVHDASTSSDS 549
           EK   KKS+++S  +            K    +    +EEA +E S   N       SDS
Sbjct: 404 EKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDS 463

Query: 550 EEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPD 609
           E  +       D+   +  E E+  +  +  +LE E  E     A   D  D + +    
Sbjct: 464 ESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHM 523

Query: 610 SRQAETEAEVKKKKNKKKNKKVN 632
              ++ E  +++KK+    ++ N
Sbjct: 524 DFLSDFEMMLQRKKSMSGKRRRN 546



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 67/333 (20%), Positives = 126/333 (37%), Gaps = 46/333 (13%)

Query: 297 SSPIMVDNDSSGTSDKDHSEILDG--ISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354
           ++P+  + DS    + D +E   G    +++ +SE  T  + D      GH      + +
Sbjct: 16  ATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPK--GHHVTDSENDE 73

Query: 355 RECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEE 414
                +  SE       ++S+S      +PPA DS+            H S ++ +E+  
Sbjct: 74  PLNLNASDSESEELHRQKDSDSESEERAEPPASDSENED------VNQHGSDSESEETR- 126

Query: 415 DPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKN 474
                              + P SD ++   L G    S  +  G    S  ++  L+K+
Sbjct: 127 -------------------KLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKS 167

Query: 475 VKLKSKYLD-MRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEE--AS 531
               S+  D ++ QI           ESE+P   ++      E     ++    EE    
Sbjct: 168 PASDSETEDALKPQIS--------DSESEEPPRHQASDSENEEPPKPRMSDSESEELPKP 219

Query: 532 QESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDS 591
           Q S S         +SDSE +++   +   + ++ + +P + Q+  S  E   +    DS
Sbjct: 220 QVSDSESEEPPRHQASDSENEELPKPR---ISDSESEDPPRHQASDSENEELPKPRISDS 276

Query: 592 LLATVPDEQ--DCVTQEVPDSRQAETEAEVKKK 622
                P  Q  D   +E+P  R +++E+E  +K
Sbjct: 277 ESEDPPRNQASDSENEELPKPRVSDSESEGPQK 309


>gi|125656165 THO complex 2 [Homo sapiens]
          Length = 1593

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 60/283 (21%), Positives = 115/283 (40%), Gaps = 42/283 (14%)

Query: 361  GQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHK 420
            G S   N G+N  SN +   N     ++ +K     T    P A    G + +E P E +
Sbjct: 1251 GNSSNGNSGSN--SNKAVKENDKEKGKEKEKEKKEKTPATTPEAR-VLGKDGKEKPKEER 1307

Query: 421  PSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSK 480
            P+K +++ E   +  P SD +        K    +    +PN   +  +  E+  K  S+
Sbjct: 1308 PNKDEKARETK-ERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERERE-KEPSR 1365

Query: 481  YLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNV 540
              D+ +++K K       K  EK     S + S V +  + + +P  E+  ++  +H + 
Sbjct: 1366 ERDIAKEMKSKEN----VKGGEKTPVSGS-LKSPVPR--SDIPEPEREQKRRKIDTHPSP 1418

Query: 541  HDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQ 600
              +ST  DS    + +K+    L  N+  P   +S                       E+
Sbjct: 1419 SHSSTVKDSL---IELKESSAKLYINHTPPPLSKS----------------------KER 1453

Query: 601  DCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG-----LPPEI 638
            +   +++  SR+   E E K +K++K+ K+ +      +PP++
Sbjct: 1454 EMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDL 1496


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 39/295 (13%)

Query: 337 DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGAN 396
           +S    +  +   E  S+  CP  G     +   +EE N    +  D P ++S+K +  N
Sbjct: 451 ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKN 510

Query: 397 TSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQK 456
             ++   A  ++ D ++E   E  P+  K S E D ++    D  +  S    + GS ++
Sbjct: 511 DCEENGLAKESEDDLNKESEEEVGPT--KESEEDDSEKESDEDCSEKQS----EDGSERE 564

Query: 457 YGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVE 516
           +         +   LEK++  +    ++   +  K        +SE   F+         
Sbjct: 565 F---------EENGLEKDLDEEGSEKELHENVLDKELE---ENDSENSEFEDD------- 605

Query: 517 KFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV 576
                  K +DEE S+         D  +    EE+D   K  DD  +    E    +  
Sbjct: 606 ----GSEKVLDEEGSERE------FDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655

Query: 577 SSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKV 631
             A + + E  + D  L    +E D    E  D ++ E +A+ K  ++   N+K+
Sbjct: 656 LEAADKKAEEGDADEKLF---EESDDKEDEDADGKEVE-DADEKLFEDDDSNEKL 706


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 39/295 (13%)

Query: 337 DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGAN 396
           +S    +  +   E  S+  CP  G     +   +EE N    +  D P ++S+K +  N
Sbjct: 451 ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKN 510

Query: 397 TSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQK 456
             ++   A  ++ D ++E   E  P+  K S E D ++    D  +  S    + GS ++
Sbjct: 511 DCEENGLAKESEDDLNKESEEEVGPT--KESEEDDSEKESDEDCSEKQS----EDGSERE 564

Query: 457 YGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVE 516
           +         +   LEK++  +    ++   +  K        +SE   F+         
Sbjct: 565 F---------EENGLEKDLDEEGSEKELHENVLDKELE---ENDSENSEFEDD------- 605

Query: 517 KFLTWVNKPMDEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV 576
                  K +DEE S+         D  +    EE+D   K  DD  +    E    +  
Sbjct: 606 ----GSEKVLDEEGSERE------FDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655

Query: 577 SSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKV 631
             A + + E  + D  L    +E D    E  D ++ E +A+ K  ++   N+K+
Sbjct: 656 LEAADKKAEEGDADEKLF---EESDDKEDEDADGKEVE-DADEKLFEDDDSNEKL 706


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 44/184 (23%), Positives = 70/184 (38%), Gaps = 14/184 (7%)

Query: 276 KTEADDKNDEKCMKVDLVSFPSSP----IMVDNDSSGTSDKDHSEIL--DGISNIKLNSE 329
           ++E DD N  + +K D     +S          DS G S +D  E L  +   N+   S 
Sbjct: 279 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 338

Query: 330 EVTQSQLDSCTSHDGHQQLSEVSSKR---ECPASGQSEPRNGGTNEESNSS-----GNTN 381
           E +Q    S   +    Q   VS  R     P +   E +    + E +SS       + 
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 398

Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
           +     DS+ S   N S++ P +   +   S+E    H  S   +S E   +E+ +   D
Sbjct: 399 SREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 458

Query: 442 DSGS 445
            S S
Sbjct: 459 SSRS 462



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 66/355 (18%), Positives = 137/355 (38%), Gaps = 46/355 (12%)

Query: 303 DNDSSGT---SDKDHSEILDGISNIKLNSEEV-TQSQLDSCTSHDGHQQLSEVSSKRECP 358
           D DS  T   S++   +  D   +    S E+  + ++DS    +G     E  S+    
Sbjct: 137 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS--KPEGGDSTQESESEEHWV 194

Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQK-SSGANTSKDRPHASGTDGDESEEDPP 417
             G     + G   E +  G  + DP +  S++ +S  N++  +   SG + +++     
Sbjct: 195 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 254

Query: 418 ------EHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYG------------- 458
                 EH   K+ R   +  +E+  S+ DD+ ++   K  S +                
Sbjct: 255 GGSQLLEHPSRKIFRKSRIS-EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 313

Query: 459 -GIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517
            G      ++    E++  +     +  ++  + ++    + ES++    +S+     + 
Sbjct: 314 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN--SSESQEEVVSESRG-DNPDP 370

Query: 518 FLTWVNKPMDEEASQESSSHDNVHDASTSSD-------SEEQDMSVKKGDDLLETNNPEP 570
             ++V    D ++S+E SSH   H  S S +       SE  + S +  +   + N+   
Sbjct: 371 TTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQ 430

Query: 571 EKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNK 625
           E  QS SS+ E ++E         +  +E D  +Q+   S++     E K    +
Sbjct: 431 EGLQSHSSSAESQSEE--------SHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 9/153 (5%)

Query: 295 FPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354
           F  S I  ++D S   D +  E +   S    NS +   SQ    +  D  +   E  S 
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS- 326

Query: 355 RECPASGQSEPRN-GGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESE 413
                  Q E +N  G + ES+   N ++   + +SQ+   + +  D P  + +  ++ E
Sbjct: 327 -------QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 379

Query: 414 EDPPEHKPSKLKRSHELDIDENPASDFDDSGSL 446
           +     + S    SH         +D + S SL
Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSESL 412



 Score = 33.5 bits (75), Expect = 0.86
 Identities = 89/422 (21%), Positives = 150/422 (35%), Gaps = 69/422 (16%)

Query: 50  DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109
           D  ++SGD    +++ G      +   +  +G DE   DS+  +  S     Q G+ +A 
Sbjct: 104 DDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDE---DSDDTIQASEESAPQ-GQDSAQ 159

Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE-----------------EDDIL 152
                S    N+ ++  K        +  QES  +E+                  +D+ +
Sbjct: 160 DTTSESRELDNEDRVDSKPEG----GDSTQESESEEHWVGGGSDGESSHGDGSELDDEGM 215

Query: 153 ASDDPSSIEQYE-NTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLW 211
            SDDP SI     N+R      K     EN    NT                + GG  L 
Sbjct: 216 QSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT---------------QDSGGSQLL 260

Query: 212 QSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTD 271
           +     HP + +      F  ++   E   S+L     +     E +  + + S S DT 
Sbjct: 261 E-----HPSRKI------FRKSRISEEDDRSELD----DNNTMEEVKSDSTENSNSRDTG 305

Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEV 331
              S+   D K D +    + +S   S   VD  SS +S + +   L    N   + EEV
Sbjct: 306 L--SQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEAN---LSSQENSSESQEEV 359

Query: 332 TQSQL----DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAE 387
                    D  TS+   Q+ S+ S +        S+  +     +S SS + N    + 
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419

Query: 388 DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPA---SDFDDSG 444
           +S +   +++ +     S +   +SEE   E   S  + S     D N     S  ++ G
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 479

Query: 445 SL 446
            L
Sbjct: 480 QL 481


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 44/184 (23%), Positives = 70/184 (38%), Gaps = 14/184 (7%)

Query: 276 KTEADDKNDEKCMKVDLVSFPSSP----IMVDNDSSGTSDKDHSEIL--DGISNIKLNSE 329
           ++E DD N  + +K D     +S          DS G S +D  E L  +   N+   S 
Sbjct: 263 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 322

Query: 330 EVTQSQLDSCTSHDGHQQLSEVSSKR---ECPASGQSEPRNGGTNEESNSS-----GNTN 381
           E +Q    S   +    Q   VS  R     P +   E +    + E +SS       + 
Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 382

Query: 382 TDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPASDFD 441
           +     DS+ S   N S++ P +   +   S+E    H  S   +S E   +E+ +   D
Sbjct: 383 SREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 442

Query: 442 DSGS 445
            S S
Sbjct: 443 SSRS 446



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 66/355 (18%), Positives = 137/355 (38%), Gaps = 46/355 (12%)

Query: 303 DNDSSGT---SDKDHSEILDGISNIKLNSEEV-TQSQLDSCTSHDGHQQLSEVSSKRECP 358
           D DS  T   S++   +  D   +    S E+  + ++DS    +G     E  S+    
Sbjct: 121 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDS--KPEGGDSTQESESEEHWV 178

Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQK-SSGANTSKDRPHASGTDGDESEEDPP 417
             G     + G   E +  G  + DP +  S++ +S  N++  +   SG + +++     
Sbjct: 179 GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDS 238

Query: 418 ------EHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYG------------- 458
                 EH   K+ R   +  +E+  S+ DD+ ++   K  S +                
Sbjct: 239 GGSQLLEHPSRKIFRKSRIS-EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 297

Query: 459 -GIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517
            G      ++    E++  +     +  ++  + ++    + ES++    +S+     + 
Sbjct: 298 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN--SSESQEEVVSESRG-DNPDP 354

Query: 518 FLTWVNKPMDEEASQESSSHDNVHDASTSSD-------SEEQDMSVKKGDDLLETNNPEP 570
             ++V    D ++S+E SSH   H  S S +       SE  + S +  +   + N+   
Sbjct: 355 TTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQ 414

Query: 571 EKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNK 625
           E  QS SS+ E ++E         +  +E D  +Q+   S++     E K    +
Sbjct: 415 EGLQSHSSSAESQSEE--------SHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 461



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 9/153 (5%)

Query: 295 FPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK 354
           F  S I  ++D S   D +  E +   S    NS +   SQ    +  D  +   E  S 
Sbjct: 252 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS- 310

Query: 355 RECPASGQSEPRN-GGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESE 413
                  Q E +N  G + ES+   N ++   + +SQ+   + +  D P  + +  ++ E
Sbjct: 311 -------QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 363

Query: 414 EDPPEHKPSKLKRSHELDIDENPASDFDDSGSL 446
           +     + S    SH         +D + S SL
Sbjct: 364 DSDSSEEDSSHTLSHSKSESREEQADSESSESL 396



 Score = 33.5 bits (75), Expect = 0.86
 Identities = 89/422 (21%), Positives = 150/422 (35%), Gaps = 69/422 (16%)

Query: 50  DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109
           D  ++SGD    +++ G      +   +  +G DE   DS+  +  S     Q G+ +A 
Sbjct: 88  DDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDE---DSDDTIQASEESAPQ-GQDSAQ 143

Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE-----------------EDDIL 152
                S    N+ ++  K        +  QES  +E+                  +D+ +
Sbjct: 144 DTTSESRELDNEDRVDSKPEG----GDSTQESESEEHWVGGGSDGESSHGDGSELDDEGM 199

Query: 153 ASDDPSSIEQYE-NTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLW 211
            SDDP SI     N+R      K     EN    NT                + GG  L 
Sbjct: 200 QSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT---------------QDSGGSQLL 244

Query: 212 QSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTD 271
           +     HP + +      F  ++   E   S+L     +     E +  + + S S DT 
Sbjct: 245 E-----HPSRKI------FRKSRISEEDDRSELD----DNNTMEEVKSDSTENSNSRDTG 289

Query: 272 TYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEV 331
              S+   D K D +    + +S   S   VD  SS +S + +   L    N   + EEV
Sbjct: 290 L--SQPRRDSKGDSQEDSKENLSQEESQ-NVDGPSSESSQEAN---LSSQENSSESQEEV 343

Query: 332 TQSQL----DSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAE 387
                    D  TS+   Q+ S+ S +        S+  +     +S SS + N    + 
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 403

Query: 388 DSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENPA---SDFDDSG 444
           +S +   +++ +     S +   +SEE   E   S  + S     D N     S  ++ G
Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 463

Query: 445 SL 446
            L
Sbjct: 464 QL 465


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 13/174 (7%)

Query: 271 DTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEE 330
           D  +  +EA D N +     D  S  S    V +D+S  S  D+S   D  S+   +  +
Sbjct: 160 DDNSDDSEAPDDNSDDSEAPDDNSDDSD---VPDDNSDDSSDDNS---DDSSDDNSDDSD 213

Query: 331 VTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSE-PRNGGTNEESNSSGNTNTDPPAEDS 389
           V   + D     D     S+V       +S  SE P +   + E+    + +++ P + S
Sbjct: 214 VPDDKSDDSDVPDDSSDDSDVPDD----SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 269

Query: 390 QKSSGANTSKDRPHASGTDGDESE--EDPPEHKPSKLKRSHELDIDENPASDFD 441
             S   + S D   AS    D+SE  +D  +   +   +S + D+ E+ + D D
Sbjct: 270 DDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSD 323



 Score = 33.5 bits (75), Expect = 0.86
 Identities = 37/187 (19%), Positives = 65/187 (34%), Gaps = 22/187 (11%)

Query: 263 DASQSCDTDTYTS----KTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEIL 318
           D+ + C T         +  +DD++ E C     +  P  PI++ +D +   D D+    
Sbjct: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEP--PIVISDDDN---DDDNG--- 133

Query: 319 DGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSG 378
                   N  EV     D   + D +   SE        +    +  +     + NS  
Sbjct: 134 --------NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185

Query: 379 NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEED--PPEHKPSKLKRSHELDIDENP 436
           +   D  ++DS   +  ++S D    S    D+S++   P +            D  E P
Sbjct: 186 SDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP 245

Query: 437 ASDFDDS 443
               DDS
Sbjct: 246 DDSSDDS 252



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 29/153 (18%), Positives = 54/153 (35%), Gaps = 9/153 (5%)

Query: 263 DASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGIS 322
           D+    D    +S   +DD +D+     D+    S    V +DSS     D S++ D  S
Sbjct: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS-----DDSDVPDDSS 239

Query: 323 NIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNT 382
           +      E      D   + D     SE        +    +  +     + +S  +  +
Sbjct: 240 D----DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEAS 295

Query: 383 DPPAEDSQKSSGANTSKDRPHASGTDGDESEED 415
           D  ++DS+     +   D P     D D  +++
Sbjct: 296 DDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 9/152 (5%)

Query: 298 SPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKREC 357
           +P   DN S  T ++      D + + +L     +   +DS ++   H       S    
Sbjct: 625 NPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFI 684

Query: 358 PASGQSEPR--NGGTNEESNSSG---NTNTDPPAEDSQKSSGANTSKDRPHASGTDGDES 412
             SG  E +  +   N+E+ ++    N  T P ++D +  +G  TS       G D  ES
Sbjct: 685 SHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQR--TGKKTSVQGQVQKGNDESES 742

Query: 413 --EEDPPEHKPSKLKRSHELDIDENPASDFDD 442
             E DPP  K S+ +   + ++ +    DF+D
Sbjct: 743 DFESDPPSPKSSEEEEQDDEEVLQGEQGDFND 774


>gi|62750354 matrin 3 [Homo sapiens]
          Length = 847

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 6/79 (7%)

Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGD-ESEEDPPEHKPSKLKRSH-E 429
           +ES S   + TD     SQK+  +   K++   SG DG+ ++++D  E +P+ L  S  E
Sbjct: 602 KESPSDKKSKTD----GSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDE 657

Query: 430 LDIDENPASDFDDSGSLLG 448
           L +DE  A+   +SGS +G
Sbjct: 658 LLVDEEEAAALLESGSSVG 676



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 20/167 (11%)

Query: 278 EADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILD--GISNIKLNSEEVTQSQ 335
           E D K+D+   + +++      ++VD + +    +  S + D   ++N+   + +  +  
Sbjct: 636 EKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEP 695

Query: 336 LDSCTSHDGH------QQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDS 389
            D     DG       ++L +V    E     ++   NG  NEE       NT+P AE S
Sbjct: 696 SDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEE-------NTEPGAESS 748

Query: 390 QKSSGANTSKDRPHASGTDGDESEED---PPEHKPSKLKRSHELDID 433
           + +   N  KD    +    DE+++D   P E++    + +  + ID
Sbjct: 749 ENADDPN--KDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGID 793


>gi|21626466 matrin 3 [Homo sapiens]
          Length = 847

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 6/79 (7%)

Query: 372 EESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGD-ESEEDPPEHKPSKLKRSH-E 429
           +ES S   + TD     SQK+  +   K++   SG DG+ ++++D  E +P+ L  S  E
Sbjct: 602 KESPSDKKSKTD----GSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDE 657

Query: 430 LDIDENPASDFDDSGSLLG 448
           L +DE  A+   +SGS +G
Sbjct: 658 LLVDEEEAAALLESGSSVG 676



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 20/167 (11%)

Query: 278 EADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILD--GISNIKLNSEEVTQSQ 335
           E D K+D+   + +++      ++VD + +    +  S + D   ++N+   + +  +  
Sbjct: 636 EKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEP 695

Query: 336 LDSCTSHDGH------QQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDS 389
            D     DG       ++L +V    E     ++   NG  NEE       NT+P AE S
Sbjct: 696 SDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEE-------NTEPGAESS 748

Query: 390 QKSSGANTSKDRPHASGTDGDESEED---PPEHKPSKLKRSHELDID 433
           + +   N  KD    +    DE+++D   P E++    + +  + ID
Sbjct: 749 ENADDPN--KDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGID 793


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 58/294 (19%), Positives = 117/294 (39%), Gaps = 36/294 (12%)

Query: 359 ASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPE 418
           +S  S   +  ++  S+SS ++++   +  S  SS ++TS  +PH    +  E       
Sbjct: 153 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKE------- 205

Query: 419 HKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGG---IPNFSHRQVRYLEKNV 475
            KPSK  R H+    E P+ D + S      K    +       +P  + ++ + + K  
Sbjct: 206 -KPSKDSREHKSAFKE-PSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEP 263

Query: 476 KLKSKYLDMRR-QIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKP------MDE 528
           K  S  L +   Q K          +SE+   KK K  S    F ++ + P        +
Sbjct: 264 KPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSAD 323

Query: 529 EASQESSSHDNVHDASTSSD-SEEQDMSVKKGDDLLETNN---------------PEPEK 572
           +   +  SH  +      S+ SE++  ++   DD+++ N+               P P  
Sbjct: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPAS 383

Query: 573 CQSVSSAGELETENYERDSLLATVPD-EQDCVTQEVPDSRQAETEAEVKKKKNK 625
             S SS+    ++  ++  L + + D   D   +E  +    + ++E+++  N+
Sbjct: 384 SSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNR 437


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 20/181 (11%)

Query: 352 SSKRECPA----SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASG- 406
           S +R  PA    SG+ +   GG++ + +       + P    Q+ +G   S    H S  
Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813

Query: 407 TDGDESEEDPPEHK-----PSKLKRSHELDIDENPASDFDDSGSLLGFKY----GSGQKY 457
           + GDE  +D   H+     PS+     E   +E+  S+   S S  G ++     S + Y
Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEE---EEDSGSEHSRSRSRSGRRHSSHRSSRRSY 870

Query: 458 GGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEK 517
               + S  Q  Y  +       Y D   + +  +K    + +S+   +  SK  SK  K
Sbjct: 871 SSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKR---SHDSDDSDYASSKHRSKRHK 927

Query: 518 F 518
           +
Sbjct: 928 Y 928



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 82/355 (23%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 296 PSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSK- 354
           P+ P ++   +S   D D++         K  S    +S + +  S    + +SEVS + 
Sbjct: 406 PNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQP 465

Query: 355 RECPASGQSEPRNGGTNEESNSSGNTNTDPPAED-SQKSSG-----ANTSKDRPHASGTD 408
           +E   +  SEP  G   E   + G   +D   E  SQK S      +N+SK+   A+   
Sbjct: 466 KETSMTEPSEP--GSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPA- 522

Query: 409 GDESEEDPPEHKPSKLKRSHELDIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQV 468
           G ES+E P +H          L  DE+ A  +  S  L+  K      Y   P +   + 
Sbjct: 523 GKESQEGP-KHPTGPF--FPVLSKDESTALQWP-SELLIFTKAEPSISYSCNPLYFDFK- 577

Query: 469 RYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDE 528
             L +N   ++K  +  + I   +K      +  +P   KSK +   EK +      MD 
Sbjct: 578 --LSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEP--NKSKEVGG-EKIVRSSGGRMDA 632

Query: 529 EASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYE 588
            AS  + S  N  +   S  SE +D           T    P K +    +   + +   
Sbjct: 633 PASGSACSGLNKQEPGGSHGSETED-----------TGRSLPSKKERSGKSHRHKKKKKH 681

Query: 589 RDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAAVPE 643
           + S       + D  T+E     ++  +++ +KK+ +KKNK       E    PE
Sbjct: 682 KKSSKHKRKHKAD--TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPE 734


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 20/187 (10%)

Query: 257 AQGWT--FDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDH 314
           A+ WT    A Q      + S++E ++ + +     +  S   S    ++   G S++D 
Sbjct: 657 AKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDS 716

Query: 315 SEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNG-GTNEE 373
           SE     S+ + +SE   +S L++           + ++KR   A G+S+  +G   NE+
Sbjct: 717 SED----SSSEQDSESGRESGLEN-----------KRTAKRNSKAKGKSDSEDGEKENEK 761

Query: 374 SNSSGNTNTDPPA-EDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDI 432
           S +S ++N +  + EDS   S + +  +    S     E E+   + +    K    LD+
Sbjct: 762 SKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDL 821

Query: 433 DE-NPAS 438
           D+ NP S
Sbjct: 822 DDFNPVS 828



 Score = 30.4 bits (67), Expect = 7.3
 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 7/105 (6%)

Query: 528 EEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENY 587
           E   +  S+ D+  D+S+  DSE    S  +     + N+    K +  S + + E EN 
Sbjct: 705 ESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNS----KAKGKSDSEDGEKEN- 759

Query: 588 ERDSLLATVPDEQDCVTQEVPDSR-QAETEAEVKKKK-NKKKNKK 630
           E+     +  DE   +     DS  ++E E+E + ++  K+K KK
Sbjct: 760 EKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKK 804



 Score = 30.0 bits (66), Expect = 9.5
 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 17/142 (11%)

Query: 50  DSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAH 109
           DS + SG ++ E+ E G      E  DS     ++S  + ++E  R  GL     + TA 
Sbjct: 691 DSESESGSESGEQGESG------EEGDSNEDSSEDSSSEQDSESGRESGLE---NKRTAK 741

Query: 110 KDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYE--EDDILASDDPSSIEQYENTR 167
           +      N++ K K   +  +K+       +S   E    ED    S+  S  E    +R
Sbjct: 742 R------NSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESR 795

Query: 168 TYELQSKKDTETENPPVENTLS 189
               + +K T+ +  P+   +S
Sbjct: 796 RVTKEKEKKTKQDRTPLTKDVS 817


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 309  TSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNG 368
            +S+KD  +  D       + EE   +        DG  + S+ SSK  C     S+  N 
Sbjct: 973  SSEKDEED--DEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSK--CSLYADSDGEND 1028

Query: 369  GTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSH 428
             T++  +SS ++++   +  S  SS +++S+       +  DE EE+ P   PS      
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSE------SSSEDEEEEERPAALPSASPPPR 1082

Query: 429  ELDI 432
            E+ +
Sbjct: 1083 EVPV 1086



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 7/122 (5%)

Query: 528  EEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVS-------SAG 580
            EEASQESSS  +  D     + E+++ +V       E ++ E E+  S S       S G
Sbjct: 966  EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDG 1025

Query: 581  ELETENYERDSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNGLPPEIAA 640
            E ++ +    S  ++        +     S  +E+ +E ++++ +         PP    
Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085

Query: 641  VP 642
            VP
Sbjct: 1086 VP 1087


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 17/156 (10%)

Query: 89  SEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEE 148
           SE   + S   P    ++TA K  EVS    +K K  +   +KK      ++  RK+ +E
Sbjct: 26  SERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKK------EDKERKKKDE 77

Query: 149 DDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGG 208
           + + A ++    E+ E  +  E + KK  E      E   + +++  E+  +   E    
Sbjct: 78  EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE---- 133

Query: 209 LLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQL 244
               +W+  H  + L S+  N PD++ E E  +S+L
Sbjct: 134 ----AWERHHLRKELRSKNQNAPDSRPE-ENFFSRL 164


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 17/156 (10%)

Query: 89  SEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEE 148
           SE   + S   P    ++TA K  EVS    +K K  +   +KK      ++  RK+ +E
Sbjct: 26  SERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKK------EDKERKKKDE 77

Query: 149 DDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGG 208
           + + A ++    E+ E  +  E + KK  E      E   + +++  E+  +   E    
Sbjct: 78  EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE---- 133

Query: 209 LLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQL 244
               +W+  H  + L S+  N PD++ E E  +S+L
Sbjct: 134 ----AWERHHLRKELRSKNQNAPDSRPE-ENFFSRL 164


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 22/156 (14%)

Query: 473 KNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQ 532
           K +  KS  L    ++K KNK +   K++EK        L+K+ KF+         E ++
Sbjct: 349 KEINEKSNILS--NEMKAKNKDV---KDTEKK-------LNKITKFI---------EENK 387

Query: 533 ESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV-SSAGELETENYERDS 591
           E  +  ++ D       +      KK +  L+ +  + E+ +S+ + +  +  E   R++
Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNN 447

Query: 592 LLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKK 627
            L    ++++   +EV DS + ET+   K+K++++K
Sbjct: 448 ALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 22/156 (14%)

Query: 473 KNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQ 532
           K +  KS  L    ++K KNK +   K++EK        L+K+ KF+         E ++
Sbjct: 349 KEINEKSNILS--NEMKAKNKDV---KDTEKK-------LNKITKFI---------EENK 387

Query: 533 ESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSV-SSAGELETENYERDS 591
           E  +  ++ D       +      KK +  L+ +  + E+ +S+ + +  +  E   R++
Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNN 447

Query: 592 LLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKK 627
            L    ++++   +EV DS + ET+   K+K++++K
Sbjct: 448 ALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 38/166 (22%), Positives = 66/166 (39%), Gaps = 10/166 (6%)

Query: 274 TSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNI--KLNSEEV 331
           T+KT+   K +E         F SSP+ +      T   + + ++   S I      E+ 
Sbjct: 510 TTKTKMQSKINENIAAASSTPF-SSPVNLSTSGRRTPG-NQTPVMPSASPILHSQGKEKA 567

Query: 332 TQSQLDSC-TSHDGHQQLSEVSSKR----ECPASGQSEPRNGGTNEESNSSGNTNT-DPP 385
             + ++   T H  H   S V   R    + P+S  SE  N    E+       +  D  
Sbjct: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE 627

Query: 386 AEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELD 431
           ++DSQ  S +N+  D   +   D D+ ++D  +      K S +L+
Sbjct: 628 SDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLN 673



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 64/333 (19%), Positives = 132/333 (39%), Gaps = 56/333 (16%)

Query: 307 SGTSDKDHSEILDGISNIKLNSE-EVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEP 365
           +G+ +  ++  + GI+   L++    +  Q  S +S  G+++ ++  SK        ++P
Sbjct: 170 NGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSK--------NQP 221

Query: 366 RNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLK 425
            +   ++  +          + +S   SG ++       S +D D+ EED  E   S ++
Sbjct: 222 LDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQS-IE 280

Query: 426 RSHELDIDENPASDFDDSGSLLGFKYG-SGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDM 484
            S + D D    +    +  +L   +G S  K  G       Q + + + + L S+    
Sbjct: 281 ESEDDDSDSESEAQHKSNNQVL--LHGISDPKADGQKATEKAQEKRIHQPLPLASE---- 334

Query: 485 RRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDAS 544
                    H F +++      K+ ++LS+   F+         +A +ES +       S
Sbjct: 335 ------SQTHSFQSQQ------KQPQVLSQQLPFIF-----QSSQAKEESVNKHTSVIQS 377

Query: 545 TSSDSEEQDMSV---KKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQD 601
           T   S  + +S+    K +  ++   P P+    V  AG   T             +E  
Sbjct: 378 TGLVSNVKPLSLVNQAKKETYMKLIVPSPD----VLKAGNKNTS------------EESS 421

Query: 602 CVTQEVPDSRQAETEA---EVKKKKNKKKNKKV 631
            +T E+   R+   +A   ++KK+++ K  KKV
Sbjct: 422 LLTSELRSKREQYKQAFPSQLKKQESSKSLKKV 454



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 239 QHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSS 298
           QH+S      +EQF+  ++   +   S+  + D      E D+++DE     D  S    
Sbjct: 578 QHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQS---- 633

Query: 299 PIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECP 358
               ++DS+  SD + SE  D     +  S+  T+ +  S        +L++ +S  + P
Sbjct: 634 ----ESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTS-------MKLNKTTSSVKSP 682

Query: 359 A---SGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGT 407
           +   +G S PRN    +   S+           +   + ++T    PH SGT
Sbjct: 683 SMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPH-SGT 733


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 41/179 (22%), Positives = 72/179 (40%), Gaps = 13/179 (7%)

Query: 269  DTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNS 328
            + D    +   DD  +E   + D  +  + P M + DS   +  D+   LD  ++ K  S
Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDN---LDSGNSNKDKS 4826

Query: 329  EEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAED 388
            ++  + + +   + DG Q   +++         Q + R+   NE     GN    P  E 
Sbjct: 4827 QQDKKEEKEEAEADDGGQGEDKINE--------QIDERDYDENEVDPYHGNQEKVPEPEA 4878

Query: 389  SQKSSGANT-SKDRPHASGTDGDESEEDPP-EHKPSKLKRSHELDIDENPASDFDDSGS 445
                   N  S+D+     TD +E EE+ P E K    +  HE +      +D ++S S
Sbjct: 4879 LDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQS 4937



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 70/378 (18%), Positives = 129/378 (34%), Gaps = 59/378 (15%)

Query: 261  TFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVS-FPSSPIMVDNDSSGTSDKDHSEILD 319
            TF   Q  D +   SK++   +++   M  D         +    +    SD +  ++  
Sbjct: 4702 TFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDK 4761

Query: 320  GISNIKLNSEEVTQSQLDSCTSHDGHQQLSEVSSKRECPASGQSEPRNGGTNEESN-SSG 378
             + +  LN EE  +         D  +   E  +K E    G  E  +    ++ N  SG
Sbjct: 4762 HMGD--LNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSG 4819

Query: 379  NTNTDPPAEDSQKSS--------GANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHEL 430
            N+N D   +D ++          G    K        D DE+E DP      K+     L
Sbjct: 4820 NSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL 4879

Query: 431  DIDENPASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKM 490
            D+ ++   D +D             K GG    +  +    E  +++K K  +   + + 
Sbjct: 4880 DLPDDLNLDSED-------------KNGG--EDTDNEEGEEENPLEIKEKPEEAGHEAEE 4924

Query: 491  KNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEASQESSSHDNVHDASTSSDSE 550
            + +      ES+ P                   +P  EE   E    +   +  T +D +
Sbjct: 4925 RGETETDQNESQSP------------------QEP--EEGPSEDDKAEGEEEMDTGADDQ 4964

Query: 551  EQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDS 610
            + D +           +PE    +   S  E + E  E        P +Q    QE  + 
Sbjct: 4965 DGDAA----------QHPEEHSEEQQQSVEEKDKEADEEGG--ENGPADQGFQPQEEEER 5012

Query: 611  RQAETEAEVKKKKNKKKN 628
              ++TE +V +   +K++
Sbjct: 5013 EDSDTEEQVPEALERKEH 5030


>gi|110349756 zygin 2 isoform 2 [Homo sapiens]
          Length = 380

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 24/164 (14%)

Query: 483 DMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEA-------SQESS 535
           ++R Q+ M +  I  +  +++P F   +++ ++E+ +     P D+E        S  S 
Sbjct: 139 ELREQLDMHS--IIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQ 196

Query: 536 SHDNVHDASTSSDSEE-QDMSVKKGDDLLE-----TNNPEPEKCQSVSSAGELETENYER 589
               +  +ST S  E  + +SV + +++LE           E  Q ++   ELE E   +
Sbjct: 197 EIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVK 256

Query: 590 DSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG 633
           +S ++ + + Q         ++Q E +   KKKK  K     NG
Sbjct: 257 NSFISVLIEVQ---------NKQKEHKETAKKKKKLKNGSSQNG 291


>gi|110349754 zygin 2 isoform 1 [Homo sapiens]
          Length = 353

 Score = 37.7 bits (86), Expect = 0.046
 Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 24/164 (14%)

Query: 483 DMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPMDEEA-------SQESS 535
           ++R Q+ M +  I  +  +++P F   +++ ++E+ +     P D+E        S  S 
Sbjct: 139 ELREQLDMHS--IIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQ 196

Query: 536 SHDNVHDASTSSDSEE-QDMSVKKGDDLLE-----TNNPEPEKCQSVSSAGELETENYER 589
               +  +ST S  E  + +SV + +++LE           E  Q ++   ELE E   +
Sbjct: 197 EIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVK 256

Query: 590 DSLLATVPDEQDCVTQEVPDSRQAETEAEVKKKKNKKKNKKVNG 633
           +S ++ + + Q         ++Q E +   KKKK  K     NG
Sbjct: 257 NSFISVLIEVQ---------NKQKEHKETAKKKKKLKNGSSQNG 291


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,248,358
Number of Sequences: 37866
Number of extensions: 1726206
Number of successful extensions: 8887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 334
Number of HSP's that attempted gapping in prelim test: 7521
Number of HSP's gapped (non-prelim): 1488
length of query: 853
length of database: 18,247,518
effective HSP length: 111
effective length of query: 742
effective length of database: 14,044,392
effective search space: 10420938864
effective search space used: 10420938864
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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