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Search of human proteins with 151101270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151101270 troponin I, cardiac [Homo sapiens]
(210 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151101270 troponin I, cardiac [Homo sapiens] 409 e-115
gi|56682969 troponin I, skeletal, slow [Homo sapiens] 217 7e-57
gi|224967106 fast-twitch skeletal muscle troponin I isoform 2 [H... 205 2e-53
gi|4507621 fast-twitch skeletal muscle troponin I isoform 1 [Hom... 204 6e-53
gi|224967057 fast-twitch skeletal muscle troponin I isoform 1 [H... 204 6e-53
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 41 8e-04
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 41 8e-04
gi|155722985 SMC5 protein [Homo sapiens] 37 0.016
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 36 0.021
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 36 0.021
gi|92091575 coiled-coil domain containing 57 [Homo sapiens] 36 0.021
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 36 0.027
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.035
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 35 0.046
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 35 0.046
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 35 0.060
gi|222537714 taxilin beta [Homo sapiens] 34 0.079
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 34 0.079
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 34 0.079
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 34 0.079
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 34 0.10
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 33 0.13
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 33 0.13
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 33 0.13
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 33 0.13
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 33 0.13
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 33 0.13
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 33 0.13
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 33 0.18
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 33 0.18
>gi|151101270 troponin I, cardiac [Homo sapiens]
Length = 210
Score = 409 bits (1051), Expect = e-115
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQE 60
MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQE
Sbjct: 1 MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQE 60
Query: 61 LEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTK 120
LEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTK
Sbjct: 61 LEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTK 120
Query: 121 NITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKED 180
NITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKED
Sbjct: 121 NITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKED 180
Query: 181 TEKENREVGDWRKNIDALSGMEGRKKKFES 210
TEKENREVGDWRKNIDALSGMEGRKKKFES
Sbjct: 181 TEKENREVGDWRKNIDALSGMEGRKKKFES 210
>gi|56682969 troponin I, skeletal, slow [Homo sapiens]
Length = 187
Score = 217 bits (552), Expect = 7e-57
Identities = 113/179 (63%), Positives = 139/179 (77%), Gaps = 1/179 (0%)
Query: 33 PHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAE 92
P ++K KI+ASRKL LK+L+L AK+ E+E EER EK R L+ R L+ GL +
Sbjct: 2 PEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSA 61
Query: 93 LQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISAD 152
LQDLCR+LHA+V+ VDEERYDIEAK N EI DL K+ DLRGKFKRP LRRVR+SAD
Sbjct: 62 LQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSAD 121
Query: 153 AMMQALLGARAKESLDLRAHLKQVKKEDTEKENR-EVGDWRKNIDALSGMEGRKKKFES 210
AM++ALLG++ K S+DLRA+LK VKKEDTEKE EVGDWRKN++A+SGMEGRKK F++
Sbjct: 122 AMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDA 180
>gi|224967106 fast-twitch skeletal muscle troponin I isoform 2 [Homo
sapiens]
Length = 182
Score = 205 bits (522), Expect = 2e-53
Identities = 102/177 (57%), Positives = 135/177 (76%), Gaps = 3/177 (1%)
Query: 36 KKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQD 95
KK+++ +R+ LK+++LQIA ELE+E R EK L+ C PL + G +E+Q+
Sbjct: 5 KKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMSEVQE 63
Query: 96 LCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMM 155
LC+QLHA++D +EE+YD+E +V K E+ D+ QK+FDLRGKFKRP LRRVR+SADAM+
Sbjct: 64 LCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAML 123
Query: 156 QALLGARAKESLDLRAHLKQVKKEDTEKEN--REVGDWRKNIDALSGMEGRKKKFES 210
+ALLG++ K +DLRA+LKQVKKEDTEKE R+VGDWRKNI+ SGMEGRKK FES
Sbjct: 124 KALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
>gi|4507621 fast-twitch skeletal muscle troponin I isoform 1 [Homo
sapiens]
Length = 182
Score = 204 bits (518), Expect = 6e-53
Identities = 101/177 (57%), Positives = 135/177 (76%), Gaps = 3/177 (1%)
Query: 36 KKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQD 95
+K+++ +R+ LK+++LQIA ELE+E R EK L+ C PL + G +E+Q+
Sbjct: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMSEVQE 63
Query: 96 LCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMM 155
LC+QLHA++D +EE+YD+E +V K E+ D+ QK+FDLRGKFKRP LRRVR+SADAM+
Sbjct: 64 LCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAML 123
Query: 156 QALLGARAKESLDLRAHLKQVKKEDTEKEN--REVGDWRKNIDALSGMEGRKKKFES 210
+ALLG++ K +DLRA+LKQVKKEDTEKE R+VGDWRKNI+ SGMEGRKK FES
Sbjct: 124 KALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
>gi|224967057 fast-twitch skeletal muscle troponin I isoform 1 [Homo
sapiens]
Length = 182
Score = 204 bits (518), Expect = 6e-53
Identities = 101/177 (57%), Positives = 135/177 (76%), Gaps = 3/177 (1%)
Query: 36 KKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQD 95
+K+++ +R+ LK+++LQIA ELE+E R EK L+ C PL + G +E+Q+
Sbjct: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMSEVQE 63
Query: 96 LCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMM 155
LC+QLHA++D +EE+YD+E +V K E+ D+ QK+FDLRGKFKRP LRRVR+SADAM+
Sbjct: 64 LCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAML 123
Query: 156 QALLGARAKESLDLRAHLKQVKKEDTEKEN--REVGDWRKNIDALSGMEGRKKKFES 210
+ALLG++ K +DLRA+LKQVKKEDTEKE R+VGDWRKNI+ SGMEGRKK FES
Sbjct: 124 KALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 40.8 bits (94), Expect = 8e-04
Identities = 29/108 (26%), Positives = 58/108 (53%), Gaps = 9/108 (8%)
Query: 32 EPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGE-------KGRALSTRCQPLE 84
E AKK+++ A +K L + ++ AE++RG+ K R LS R +PL+
Sbjct: 126 EEEAKKRAEDDAKKKKVLSNMGAHFGGYLVK--AEQKRGKRQTGREMKVRILSERKKPLD 183
Query: 85 LAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI 132
+ +G +L++ ++L + +++ E++D+ AK+ + EI L +I
Sbjct: 184 IDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRI 231
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 40.8 bits (94), Expect = 8e-04
Identities = 29/108 (26%), Positives = 58/108 (53%), Gaps = 9/108 (8%)
Query: 32 EPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGE-------KGRALSTRCQPLE 84
E AKK+++ A +K L + ++ AE++RG+ K R LS R +PL+
Sbjct: 137 EEEAKKRAEDDAKKKKVLSNMGAHFGGYLVK--AEQKRGKRQTGREMKVRILSERKKPLD 194
Query: 85 LAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI 132
+ +G +L++ ++L + +++ E++D+ AK+ + EI L +I
Sbjct: 195 IDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRI 242
>gi|155722985 SMC5 protein [Homo sapiens]
Length = 1101
Score = 36.6 bits (83), Expect = 0.016
Identities = 22/84 (26%), Positives = 46/84 (54%), Gaps = 8/84 (9%)
Query: 103 RVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGAR 162
R+++++ ER+++EA++ + T+I + +QK K K+ + R + + QAL+ +
Sbjct: 309 RIEEMENERHNLEARIKEKATDIKEASQKC-----KQKQDVIERKDKHIEELQQALI-VK 362
Query: 163 AKESLDLRAHLKQVKK--EDTEKE 184
E LD + + +K ED + E
Sbjct: 363 QNEELDRQRRIGNTRKMIEDLQNE 386
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.2 bits (82), Expect = 0.021
Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 46 KLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVD 105
+LQ K LQ +ELE E E R + +A R DL R+L +
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQR--------------SDLSRELEEISE 1154
Query: 106 KVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQ-ALLGARAK 164
+++E A++ N A+ + +R + TL+ +A + A A
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQK----MRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 165 ESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKK 207
E +D +KQ +++ + E+ D N++ +S +G +K
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEK 1253
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.2 bits (82), Expect = 0.021
Identities = 37/163 (22%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 46 KLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVD 105
+LQ K LQ +ELE E E R + +A R DL R+L +
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQR--------------SDLSRELEEISE 1154
Query: 106 KVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQ-ALLGARAK 164
+++E A++ N A+ + +R + TL+ +A + A A
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQK----MRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 165 ESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKK 207
E +D +KQ +++ + E+ D N++ +S +G +K
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEK 1253
>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
Length = 915
Score = 36.2 bits (82), Expect = 0.021
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 38/185 (20%)
Query: 19 IRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQI---------AKQELEREAEERR 69
+R+R +R A S + SR+L++K L ++ A + L+R AE
Sbjct: 182 MRKREHEFRL-----QADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQR-AEATN 235
Query: 70 GEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLT 129
E R L +R ELQDL ARV ++++ + ++ LT
Sbjct: 236 AELERKLQSRA----------GELQDLEAMSRARVKDLEDKLHSVQ------------LT 273
Query: 130 QKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKE-DTEKENREV 188
+K + K K L R+ DA++ A+ GA ++ +L+ + +++ +T +
Sbjct: 274 RKKEEETFKRKHEELDRLAREKDAVLVAVKGAHVEQLQELQTRVLELQAHCETLEAQLRR 333
Query: 189 GDWRK 193
+WR+
Sbjct: 334 AEWRQ 338
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 35.8 bits (81), Expect = 0.027
Identities = 42/202 (20%), Positives = 84/202 (41%), Gaps = 34/202 (16%)
Query: 36 KKKSKISASRKL-QLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQ 94
+ K K+ KL Q T+ ++ KQ+L+ + E++ E +S +E +LQ
Sbjct: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFE----ISNLISKIEDEQAVEIQLQ 1108
Query: 95 DLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFK-------------- 140
++L AR++++ EE A K + +DL++++ ++ + +
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 1168
Query: 141 ---------RPTLRRVRISADAMMQALLGARAK------ESLDLRAHLKQVKKEDTEKEN 185
R L + +AM+ AL A E +D +KQ +++ +
Sbjct: 1169 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Query: 186 REVGDWRKNIDALSGMEGRKKK 207
E D N +A+S +G +K
Sbjct: 1229 METDDLSSNAEAISKAKGNLEK 1250
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 35.4 bits (80), Expect = 0.035
Identities = 40/194 (20%), Positives = 86/194 (44%), Gaps = 34/194 (17%)
Query: 36 KKKSKISASRKLQLKTLL-LQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQ 94
+ K K+ K+ ++++ L+ KQ++E + +++ E + L + ++ L F Q
Sbjct: 1054 RAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ-LQAKIDDEQVHSLQF---Q 1109
Query: 95 DLCRQLHARVDKVDEE---RYDIEAKVTKNITEIADLTQKIFD----------------- 134
++L AR+++++EE + + AK+ K +++A ++I +
Sbjct: 1110 KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNK 1169
Query: 135 --------LRGKFKRPTLRRVRISADAMM-QALLGARAKESLDLRAHLKQVKKEDTEKEN 185
+R + TL+ +A QA A E +D +KQ +++ +
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELK 1229
Query: 186 REVGDWRKNIDALS 199
E+ D NI+ALS
Sbjct: 1230 MEIDDMASNIEALS 1243
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 35.0 bits (79), Expect = 0.046
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 16/192 (8%)
Query: 32 EPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEE-RRG-EKGRALSTRCQPLELAGLG 89
E + + + + + + +K LQ+ +ELE E E+ ++G E +A + + LE++ G
Sbjct: 701 EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760
Query: 90 F----AELQDLCRQLHARVDKVDEERYDIEAK---VTKNITEIADLTQKIFDLRGKFKRP 142
LQ + ++ +++ E D+E + + KN+ E+ ++++ L + K
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Query: 143 TLRRVRISADAMMQALLGARAKESLDLR---AHLKQVKKEDTEKEN----REVGDWRKNI 195
++ D R ++ +++ VK + EKEN +E+G ++++
Sbjct: 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESC 880
Query: 196 DALSGMEGRKKK 207
L +E K+
Sbjct: 881 VRLKELEKENKE 892
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 35.0 bits (79), Expect = 0.046
Identities = 38/192 (19%), Positives = 87/192 (45%), Gaps = 16/192 (8%)
Query: 32 EPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEE-RRG-EKGRALSTRCQPLELAGLG 89
E + + + + + + +K LQ+ +ELE E E+ ++G E +A + + LE++ G
Sbjct: 701 EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760
Query: 90 F----AELQDLCRQLHARVDKVDEERYDIEAK---VTKNITEIADLTQKIFDLRGKFKRP 142
LQ + ++ +++ E D+E + + KN+ E+ ++++ L + K
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Query: 143 TLRRVRISADAMMQALLGARAKESLDLR---AHLKQVKKEDTEKEN----REVGDWRKNI 195
++ D R ++ +++ VK + EKEN +E+G ++++
Sbjct: 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESC 880
Query: 196 DALSGMEGRKKK 207
L +E K+
Sbjct: 881 VRLKELEKENKE 892
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 34.7 bits (78), Expect = 0.060
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 27/168 (16%)
Query: 32 EPHAKKKSKISASRKLQLKTLLLQIAKQELEREAE-ERRGEKGRALSTRCQPLELAGLGF 90
+ + K+K+++ A KL ++++ K+++ REAE E E+ R R + E+A
Sbjct: 320 DENQKQKAELLAQEKLA-DQMVMEFTKKKMAREAEFEAEQERIR----REKEKEIA---- 370
Query: 91 AELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKR----PTLRR 146
+L A +K + + + +A K E+AD + + K+ LR+
Sbjct: 371 --------RLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRK 422
Query: 147 VRISADAMMQALLGARAKESLD-----LRAHLKQVKKEDTEKENREVG 189
R+ A + L + + D LRA +Q++KE E+E + G
Sbjct: 423 SRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATG 470
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 34.3 bits (77), Expect = 0.079
Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 16/108 (14%)
Query: 45 RKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARV 104
R Q K LLQ + ++++E ++ +GE RA+ R ++L+ LCR+L
Sbjct: 177 RTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILAR-----------SKLESLCRELQRHN 225
Query: 105 DKVDEE---RYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRI 149
+ EE R E + K IT + + D++G+ ++ + R +++
Sbjct: 226 KTLKEEALQRAREEEEKRKEIT--SHFQSTLTDIQGQIEQQSERNMKL 271
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 34.3 bits (77), Expect = 0.079
Identities = 25/118 (21%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQ----IAKQELEREAEERRGE-KGR 74
+ R + +A E AK++++ +K L ++ +AK + +R ++ E K +
Sbjct: 116 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 175
Query: 75 ALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI 132
L+ R +PL + LG +L+D ++L + +++ ++++ K+ + +I L +I
Sbjct: 176 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 233
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 34.3 bits (77), Expect = 0.079
Identities = 25/118 (21%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQ----IAKQELEREAEERRGE-KGR 74
+ R + +A E AK++++ +K L ++ +AK + +R ++ E K +
Sbjct: 118 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 177
Query: 75 ALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI 132
L+ R +PL + LG +L+D ++L + +++ ++++ K+ + +I L +I
Sbjct: 178 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 235
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 34.3 bits (77), Expect = 0.079
Identities = 25/118 (21%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQ----IAKQELEREAEERRGE-KGR 74
+ R + +A E AK++++ +K L ++ +AK + +R ++ E K +
Sbjct: 110 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 169
Query: 75 ALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI 132
L+ R +PL + LG +L+D ++L + +++ ++++ K+ + +I L +I
Sbjct: 170 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 227
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 33.9 bits (76), Expect = 0.10
Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 19/148 (12%)
Query: 48 QLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPL-ELAGLGFAELQDLCRQ------- 99
+LKTL +KQ E + +K + L CQ + E AEL+ +C Q
Sbjct: 296 ELKTLYR--SKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNN 353
Query: 100 -----LHARVDKVDEERYDIEAKVTKNITE-IADLTQKIFDLRGKFKRPT--LRRVRISA 151
LH V ++++E++D++ + T+NI E + D ++ + ++ T +
Sbjct: 354 DWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKEL 413
Query: 152 DAMMQALLGARAKESLDLRAHLKQVKKE 179
+A +Q L G +L R L Q K E
Sbjct: 414 EARVQQLTGEAENSNLQ-RQKLIQEKAE 440
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 33.5 bits (75), Expect = 0.13
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 14/134 (10%)
Query: 27 RAYATEPHAKKKSKISASRKLQLKTLLL--QIAKQELEREAEERRGEKGRALSTRCQPLE 84
RA A+ + + +R L L L Q A++ELER+ R E LS++ +
Sbjct: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSK----D 1546
Query: 85 LAGLGFAELQDLCR-------QLHARVDKVDEERYDIE-AKVTKNITEIADLTQKIFDLR 136
G EL+ CR L A+V ++++E E AK+ +T A TQ DL+
Sbjct: 1547 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1606
Query: 137 GKFKRPTLRRVRIS 150
G+ + RR +++
Sbjct: 1607 GRDEAGEERRRQLA 1620
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 33.5 bits (75), Expect = 0.13
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 14/134 (10%)
Query: 27 RAYATEPHAKKKSKISASRKLQLKTLLL--QIAKQELEREAEERRGEKGRALSTRCQPLE 84
RA A+ + + +R L L L Q A++ELER+ R E LS++ +
Sbjct: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSK----D 1538
Query: 85 LAGLGFAELQDLCR-------QLHARVDKVDEERYDIE-AKVTKNITEIADLTQKIFDLR 136
G EL+ CR L A+V ++++E E AK+ +T A TQ DL+
Sbjct: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1598
Query: 137 GKFKRPTLRRVRIS 150
G+ + RR +++
Sbjct: 1599 GRDEAGEERRRQLA 1612
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 33.5 bits (75), Expect = 0.13
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 14/134 (10%)
Query: 27 RAYATEPHAKKKSKISASRKLQLKTLLL--QIAKQELEREAEERRGEKGRALSTRCQPLE 84
RA A+ + + +R L L L Q A++ELER+ R E LS++ +
Sbjct: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSK----D 1579
Query: 85 LAGLGFAELQDLCR-------QLHARVDKVDEERYDIE-AKVTKNITEIADLTQKIFDLR 136
G EL+ CR L A+V ++++E E AK+ +T A TQ DL+
Sbjct: 1580 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1639
Query: 137 GKFKRPTLRRVRIS 150
G+ + RR +++
Sbjct: 1640 GRDEAGEERRRQLA 1653
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 33.5 bits (75), Expect = 0.13
Identities = 38/202 (18%), Positives = 86/202 (42%), Gaps = 34/202 (16%)
Query: 36 KKKSKISASRKL-QLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQ 94
+ K K+ KL Q T+ ++ KQ+L+ + +++ E L ++ + + G+ +LQ
Sbjct: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS-GLQSKIEDEQALGM---QLQ 1109
Query: 95 DLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFK-------------- 140
++L AR+++++EE A K + +DL++++ ++ + +
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169
Query: 141 ---------RPTLRRVRISADAMMQALLGARAK------ESLDLRAHLKQVKKEDTEKEN 185
R L + +A L A E +D +KQ +++ +
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1229
Query: 186 REVGDWRKNIDALSGMEGRKKK 207
E+ D N++ +S +G +K
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEK 1251
Score = 28.1 bits (61), Expect = 5.6
Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 17/192 (8%)
Query: 21 RRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRC 80
R N +A + + + L+ + +++ L+ E EE R + +R
Sbjct: 1645 RNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSR- 1703
Query: 81 QPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFK 140
++A + + + LH + + + +E +++ E+ D+ Q+ + K K
Sbjct: 1704 ---KIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760
Query: 141 RPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKK--EDTEKENREVGDWRKNIDAL 198
+ DA M A K+ D AHL+++KK E T K+ + D + + AL
Sbjct: 1761 KAI-------TDAAMMA---EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL-AL 1809
Query: 199 SGMEGRKKKFES 210
G + + +K E+
Sbjct: 1810 KGGKKQIQKLEA 1821
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 33.5 bits (75), Expect = 0.13
Identities = 41/186 (22%), Positives = 79/186 (42%), Gaps = 32/186 (17%)
Query: 44 SRKLQLKTLLLQIAKQELEREAEERRGEKGRALST--------RCQPLELAGLGFA---- 91
++ L+ + LL +EL E+ GE+ R L+ R L G
Sbjct: 1720 AQALERRASLLAAELEELRAALEQ--GERSRRLAEQELLEATERLNLLHSQNTGLLNQKK 1777
Query: 92 ELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKI---------FDLRGKFKRP 142
+L+ QL V++ +ER + E K K IT+ A + +++ + K
Sbjct: 1778 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQ 1837
Query: 143 TLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKE-DTEKENREVGDWRKNIDALSGM 201
T+R ++ + QA L K+ L A +++++ E D E+ +K+ +AL G+
Sbjct: 1838 TVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQ--------KKHAEALKGV 1889
Query: 202 EGRKKK 207
+++
Sbjct: 1890 RKHERR 1895
Score = 27.7 bits (60), Expect = 7.4
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 11/151 (7%)
Query: 59 QELEREAEERRGEKGR---ALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIE 115
QELE+ + GEK AL LEL +Q Q+ A VD+ E+ +
Sbjct: 1573 QELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEEC 1632
Query: 116 AKVTKNITEIADLTQKIFDLRGKFKRPTLR-RVRISADAM-MQALLGARAKESLDLRAHL 173
A + +N + Q D + + LR + ++ D ++ LG +++ + +A
Sbjct: 1633 ANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAAT 1692
Query: 174 K----QVKKEDT--EKENREVGDWRKNIDAL 198
+ Q+K+E ++E R + + AL
Sbjct: 1693 RLMQAQLKEEQAGRDEEQRLAAELHEQAQAL 1723
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 33.5 bits (75), Expect = 0.13
Identities = 14/50 (28%), Positives = 30/50 (60%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERR 69
+ R R A + +++ ++ A R+LQ + L++ K++L+RE EE++
Sbjct: 710 QERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 759
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 33.5 bits (75), Expect = 0.13
Identities = 14/50 (28%), Positives = 30/50 (60%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERR 69
+ R R A + +++ ++ A R+LQ + L++ K++L+RE EE++
Sbjct: 706 QERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 33.1 bits (74), Expect = 0.18
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 44 SRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHAR 103
+ KLQL+ L A+ EL EAEE R L+ + Q EL+++C L AR
Sbjct: 880 AEKLQLQEQLQ--AETELCAEAEELRAR----LTAKKQ----------ELEEICHDLEAR 923
Query: 104 VDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISA 151
V++ +E ++A+ K I +L +++ + ++ L +V A
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
Score = 32.3 bits (72), Expect = 0.30
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 28/192 (14%)
Query: 43 ASRKLQLKTLLLQIAKQELEREA-----EERRGEKGRALSTRCQPLELAGLGFAELQDLC 97
A + Q+ L +Q+AK+E E +A EE +K AL + + LE +ELQ+
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK-KIRELESQ---ISELQEDL 1120
Query: 98 RQLHARVDKVDEERYDIEAKVTKNITEIADL---TQKIFDLRGK------FKRPTLRRVR 148
A +K ++++ D+ ++ TE+ D T +LR K + TL
Sbjct: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
Query: 149 ISADAMMQALLGARAKESLDLRAHLKQVK---------KEDTEKENREVGDWRK-NIDAL 198
+ +A +Q + ++ +L L+Q K K+ E E E+ + K +
Sbjct: 1181 KTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 199 SGMEGRKKKFES 210
E ++KK E+
Sbjct: 1241 GDSEHKRKKVEA 1252
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 33.1 bits (74), Expect = 0.18
Identities = 25/127 (19%), Positives = 65/127 (51%), Gaps = 6/127 (4%)
Query: 20 RRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQ----IAKQELEREAEERRGE-KGR 74
+ R + +A E AK++++ +K L ++ +AK + +R ++ E K +
Sbjct: 110 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 169
Query: 75 ALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFD 134
L+ R +PL + LG +L+D ++L + +++ ++++ K+ + +I ++ ++
Sbjct: 170 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARV-Q 228
Query: 135 LRGKFKR 141
+ KF +
Sbjct: 229 MLAKFSK 235
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,132,570
Number of Sequences: 37866
Number of extensions: 291443
Number of successful extensions: 2099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 1946
Number of HSP's gapped (non-prelim): 266
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.