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Search of human proteins with 150417971
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150417971 supervillin isoform 1 [Homo sapiens]
(1788 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150417971 supervillin isoform 1 [Homo sapiens] 3580 0.0
gi|150417973 supervillin isoform 2 [Homo sapiens] 3020 0.0
gi|17572824 advillin [Homo sapiens] 182 3e-45
gi|194394237 villin 1 [Homo sapiens] 177 1e-43
gi|94721268 villin-like protein [Homo sapiens] 162 3e-39
gi|4504165 gelsolin isoform a precursor [Homo sapiens] 139 3e-32
gi|38044288 gelsolin isoform b [Homo sapiens] 139 3e-32
gi|189083782 gelsolin isoform c [Homo sapiens] 139 3e-32
gi|189083780 gelsolin isoform c [Homo sapiens] 139 3e-32
gi|189083778 gelsolin isoform b [Homo sapiens] 139 3e-32
gi|189083776 gelsolin isoform b [Homo sapiens] 139 3e-32
gi|189083774 gelsolin isoform b [Homo sapiens] 139 3e-32
gi|189083772 gelsolin isoform b [Homo sapiens] 139 3e-32
gi|162951877 scinderin isoform 1 [Homo sapiens] 135 5e-31
gi|4503743 flightless I homolog [Homo sapiens] 107 1e-22
gi|14916473 scinderin isoform 2 [Homo sapiens] 106 2e-22
gi|63252913 gelsolin-like capping protein [Homo sapiens] 62 7e-09
gi|87299628 biorientation of chromosomes in cell division 1-like... 46 4e-04
gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 44 0.001
gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Ho... 44 0.001
gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 44 0.001
gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 44 0.001
gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 44 0.001
gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 44 0.001
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 42 0.005
gi|153792514 actin binding LIM protein family, member 2 isoform ... 41 0.012
gi|194272204 actin binding LIM protein family, member 2 isoform ... 41 0.012
gi|194272202 actin binding LIM protein family, member 2 isoform ... 41 0.012
gi|194272200 actin binding LIM protein family, member 2 isoform ... 41 0.012
gi|194272198 actin binding LIM protein family, member 2 isoform ... 41 0.012
>gi|150417971 supervillin isoform 1 [Homo sapiens]
Length = 1788
Score = 3580 bits (9283), Expect = 0.0
Identities = 1788/1788 (100%), Positives = 1788/1788 (100%)
Query: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE
Sbjct: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
Query: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY
Sbjct: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
Query: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG
Sbjct: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
Query: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT
Sbjct: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
Query: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPRCTSHSETPTVDDEEKVDERAKLSV 300
EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPRCTSHSETPTVDDEEKVDERAKLSV
Sbjct: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPRCTSHSETPTVDDEEKVDERAKLSV 300
Query: 301 AAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATLQASA 360
AAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATLQASA
Sbjct: 301 AAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATLQASA 360
Query: 361 HQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRM 420
HQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRM
Sbjct: 361 HQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRM 420
Query: 421 NARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASA 480
NARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASA
Sbjct: 421 NARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASA 480
Query: 481 TDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKY 540
TDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKY
Sbjct: 481 TDYKFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKY 540
Query: 541 GSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQ 600
GSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQ
Sbjct: 541 GSFEEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQ 600
Query: 601 GNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQ 660
GNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQ
Sbjct: 601 GNLDLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQ 660
Query: 661 DSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRL 720
DSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRL
Sbjct: 661 DSSEQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRL 720
Query: 721 SRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAA 780
SRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAA
Sbjct: 721 SRRQEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAA 780
Query: 781 NDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLK 840
NDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLK
Sbjct: 781 NDSTQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLK 840
Query: 841 LDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEM 900
LDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEM
Sbjct: 841 LDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEM 900
Query: 901 DEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVA 960
DEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVA
Sbjct: 901 DEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVA 960
Query: 961 FMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLL 1020
FMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLL
Sbjct: 961 FMESKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLL 1020
Query: 1021 QIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTK 1080
QIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTK
Sbjct: 1021 QIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTK 1080
Query: 1081 RELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIY 1140
RELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIY
Sbjct: 1081 RELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIY 1140
Query: 1141 RLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
RLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHL
Sbjct: 1141 RLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
Query: 1201 WNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELK 1260
WNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELK
Sbjct: 1201 WNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELK 1260
Query: 1261 RSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQ 1320
RSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQ
Sbjct: 1261 RSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQ 1320
Query: 1321 FEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAA 1380
FEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAA
Sbjct: 1321 FEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAA 1380
Query: 1381 GKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVH 1440
GKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVH
Sbjct: 1381 GKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVH 1440
Query: 1441 SGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
SGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH
Sbjct: 1441 SGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWH 1500
Query: 1501 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKA 1560
GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKA
Sbjct: 1501 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKA 1560
Query: 1561 YDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPAL 1620
YDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPAL
Sbjct: 1561 YDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPAL 1620
Query: 1621 FLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLI 1680
FLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLI
Sbjct: 1621 FLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLI 1680
Query: 1681 HAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARP 1740
HAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARP
Sbjct: 1681 HAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARP 1740
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
Sbjct: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 3020 bits (7830), Expect = 0.0
Identities = 1513/1545 (97%), Positives = 1513/1545 (97%), Gaps = 32/1545 (2%)
Query: 276 RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR 335
RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR
Sbjct: 670 RCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRR 729
Query: 336 LQDRSLTQPITTEEVVIAAT--------------------------------LQASAHQK 363
LQDRSLTQPITTEEVVIAAT LQASAHQK
Sbjct: 730 LQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLPSPTVARSAVQPARLQASAHQK 789
Query: 364 ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR 423
ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR
Sbjct: 790 ALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR 849
Query: 424 YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY 483
YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY
Sbjct: 850 YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTVASTVAPMYAGDLRTKPPLDHNASATDY 909
Query: 484 KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF 543
KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF
Sbjct: 910 KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGMLREYGETESKRALTGRDSGMEKYGSF 969
Query: 544 EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL 603
EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL
Sbjct: 970 EEAEASYPILNRAREGDSHKESKYAVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNL 1029
Query: 604 DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS 663
DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS
Sbjct: 1030 DLRDRLPFEEKVEVENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSS 1089
Query: 664 EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR 723
EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR
Sbjct: 1090 EQPQEKLCKNPCAMFAAGEIKTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR 1149
Query: 724 QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS 783
QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS
Sbjct: 1150 QEGGKAPASSLHTQEAGRSLIKKRVTESRESQMTIEERKQLITVREEAWKTRGRGAANDS 1209
Query: 784 TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR 843
TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR
Sbjct: 1210 TQFTVAGRMVKKGLASPTAITPVASPICGKTRGTTPVSKPLEDIEARPDMQLESDLKLDR 1269
Query: 844 LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED 903
LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED
Sbjct: 1270 LETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVEMDED 1329
Query: 904 FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME 963
FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME
Sbjct: 1330 FDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFME 1389
Query: 964 SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1023
SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK
Sbjct: 1390 SKRMKVEKMSSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK 1449
Query: 1024 GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL 1083
GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL
Sbjct: 1450 GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKREL 1509
Query: 1084 GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM 1143
GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM
Sbjct: 1510 GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNCIYRLM 1569
Query: 1144 DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG 1203
DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG
Sbjct: 1570 DDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNG 1629
Query: 1204 TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN 1263
TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN
Sbjct: 1630 TFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSN 1689
Query: 1264 EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI 1323
EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI
Sbjct: 1690 EKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI 1749
Query: 1324 TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE 1383
TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE
Sbjct: 1750 TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE 1809
Query: 1384 KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR 1443
KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR
Sbjct: 1810 KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGR 1869
Query: 1444 REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK 1503
REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK
Sbjct: 1870 REEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCK 1929
Query: 1504 AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC 1563
AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC
Sbjct: 1930 AQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDC 1989
Query: 1564 MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV 1623
MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV
Sbjct: 1990 MLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV 2049
Query: 1624 DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG 1683
DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG
Sbjct: 2050 DNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG 2109
Query: 1684 LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE 1743
LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE
Sbjct: 2110 LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPE 2169
Query: 1744 GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
Sbjct: 2170 GVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 2214
Score = 548 bits (1411), Expect = e-155
Identities = 280/326 (85%), Positives = 294/326 (90%)
Query: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE
Sbjct: 1 MKRKERIARRLEGIENDTQPILLQSCTGLVTHRLLEEDTPRYMRASDPASPHIGRSNEEE 60
Query: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY
Sbjct: 61 ETSDSSLEKQTRSKYCTETSGVHGDSPYGSGTMDTHSLESKAERIARYKAERRRQLAEKY 120
Query: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG
Sbjct: 121 GLTLDPEADSEYLSRYTKSRKEPDAVEKRGGKSDKQEESSRDASSLYPGTETMGLRTCAG 180
Query: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT
Sbjct: 181 ESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLSPAAESSSTFSFSGRDSSFT 240
Query: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPRCTSHSETPTVDDEEKVDERAKLSV 300
EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARP + + + D + ++
Sbjct: 241 EVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEARPSTGKPKHEWFLQKDSEGDTPSLINW 300
Query: 301 AAKRLLFREMEKSFDEQNVPKRRSRN 326
++ + ++ K +N P+ S +
Sbjct: 301 PSRVKVREKLVKEESARNSPELASES 326
Score = 38.1 bits (87), Expect = 0.077
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 15/124 (12%)
Query: 316 EQNVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEVVIAATLQASAHQKALAKDQTNEGKE 375
E+ R+ R R+ +R TQPIT+ E + + ++H + D + E
Sbjct: 631 ERERGSRKPRRYFSPGESRKTSERFRTQPITSAER--KESDRCTSHSETPTVDDEEKVDE 688
Query: 376 LAEQGEPDSSTLSLAEKLALFNKLS-----QPVSKAISTRNRIDTRQRRMNARYQTQPVT 430
A+ LS+A K LF ++ Q V K S ++ R RR+ R TQP+T
Sbjct: 689 RAK--------LSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRSLTQPIT 740
Query: 431 LGEV 434
EV
Sbjct: 741 TEEV 744
>gi|17572824 advillin [Homo sapiens]
Length = 819
Score = 182 bits (461), Expect = 3e-45
Identities = 208/801 (25%), Positives = 328/801 (40%), Gaps = 148/801 (18%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
LL +KG+R+++ VE + N GD FLL W G +N E+ KA LA I+
Sbjct: 136 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 195
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-EDELYEAAIIETN 1137
RE G RA I IE A+ + K+L +S P DE+ + T
Sbjct: 196 D-RERGGRAE-IGVIE---GDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTI 250
Query: 1138 CIYRLMDD--KLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAF 1194
+Y + D +L + + + LL + + D G+++YVW GK T A+++ A
Sbjct: 251 MLYHISDSAGQLAVTEVATRPLVQ-DLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
Query: 1195 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1254
A + ++ ++ G E+ +FK+ F
Sbjct: 310 SKALGFIKMKSYPSSTNVETVNDGA-------------------------ESAMFKQLFQ 344
Query: 1255 DWTELKRS----NEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
W+ ++ + G++A+ +D +DVT + + P+ A + V+ G G
Sbjct: 345 KWSVKDQTMGLGKTFSIGKIAKVFQDK------FDVTLLHTKPEVAAQERM--VDDGNG- 395
Query: 1311 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1370
V+VW I + + Q G F+ GD Y+V + + V+
Sbjct: 396 ----------------KVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN------ 433
Query: 1371 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEE---RGAQVQVLQGKEPP 1427
GK + + WQGRH++ E SA VE+D + QV+V G EP
Sbjct: 434 ----------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPR 483
Query: 1428 CFLQCFQGGMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1486
F+ F+G +V+ G + RL+ + G +EV SSL S
Sbjct: 484 HFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND-- 541
Query: 1487 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1546
V L +A YLW+G + + + + A+ + + S+ T+ E G EP
Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD----------GSENTVAE---GQEP 588
Query: 1547 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 1606
FWD LG + A D LQ + RLF S+ +G F TE
Sbjct: 589 AEFWDLLGGKTPYANDKRLQQE-ILDVQSRLFECSNKTGQFVVTEIT------------D 635
Query: 1607 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 1666
F Q+DL + L+D +V+LW G A A++++SA+ T QY
Sbjct: 636 FTQDDLNPTD---VMLLDTWDQVFLWIG---------AEAN---ATEKESALATAQQYLH 680
Query: 1667 GK-NLKKPAPKSYLIHAGLEPLTFTNMFPSW---------------EHREDIAEITEMDT 1710
+ + P +I G EP FT F +W E D A I +
Sbjct: 681 THPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITA 740
Query: 1711 EVSNQITLVEDVLAKLCKTIYPLADLLA---RPLPEGVDPLKLEIYLTDEDFEFALDMTR 1767
++ N + ++ YP+A LL + LPE V+P K E YL+++DF +TR
Sbjct: 741 DMKNATLSLNSNDSE--PKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITR 798
Query: 1768 DEYNALPAWKQVNLKKAKGLF 1788
++ ALP WKQ+ +KK KGLF
Sbjct: 799 GQFAALPGWKQLQMKKEKGLF 819
Score = 61.2 bits (147), Expect = 9e-09
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 23/192 (11%)
Query: 1010 SAVPYKRLMLLQIKGRRHVQTRLVEPRA--SALNSGDCFLLLSPHCCFLWVGEFANVIEK 1067
+A P + L QI G T+ VE A S+LNS D FLL + +LW G+ ++ E+
Sbjct: 505 NAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDER 564
Query: 1068 AKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-ED 1126
A A ELA+L+ E T+ EG +FW LLGG+T Y A D + +
Sbjct: 565 AMAKELASLLCDGSE--------NTVAEG-----QEPAEFWDLLGGKTPY--ANDKRLQQ 609
Query: 1127 ELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVT 1186
E+ + C + + D+ L P +V++ D +V++W G E
Sbjct: 610 EILDVQSRLFECSNKTGQFVVTEITDF-----TQDDLNPTDVMLLDTWDQVFLWIGAEAN 664
Query: 1187 LAQRKIAFQLAK 1198
+++ A A+
Sbjct: 665 ATEKESALATAQ 676
Score = 58.9 bits (141), Expect = 4e-08
Identities = 84/383 (21%), Positives = 157/383 (40%), Gaps = 62/383 (16%)
Query: 1330 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1389
VW I + + + +P + G F+EGD YV+ +ST R A F
Sbjct: 18 VWRIEKMELALVPVSAHGNFYEGDCYVI-----LSTR-----------RVASLLSQDIHF 61
Query: 1390 WQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSG---- 1442
W G+ S+ E+ +A+ T +LD+ G Q + +Q E F F+ G++ G
Sbjct: 62 WIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVAS 121
Query: 1443 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGC 1502
+ E N RL V+G+ + +E++ +R + +L++ K +I W+G
Sbjct: 122 GMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSF---NRGDVFLLDLGKVIIQ-WNGP 177
Query: 1503 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDALGRRD--- 1557
++ + + A I+++ E G + V + + S L D LGRR
Sbjct: 178 ESNSGERLKAMLLAKDIRDR---ERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 234
Query: 1558 RKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQ 1617
D ++ L+ +S S+G A TE V++ P +Q+ L
Sbjct: 235 PTVPDEIIDQKQKSTI--MLYHISDSAGQLAVTE----------VATRPLVQDLLNH--D 280
Query: 1618 PALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKS 1677
L + ++Y+W+G G+ + +++++AM L + K K+ +
Sbjct: 281 DCYILDQSGTKIYVWKG--------KGATK----AEKQAAMSKALGFIKMKSYPS-STNV 327
Query: 1678 YLIHAGLEPLTFTNMFPSWEHRE 1700
++ G E F +F W ++
Sbjct: 328 ETVNDGAESAMFKQLFQKWSVKD 350
>gi|194394237 villin 1 [Homo sapiens]
Length = 827
Score = 177 bits (448), Expect = 1e-43
Identities = 199/799 (24%), Positives = 320/799 (40%), Gaps = 139/799 (17%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
LL +KG+R+V VE + N GD FLL W G + +E+ + LA I+
Sbjct: 139 LLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIR 198
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
+ G TY+ ++ + + + G+ A P D + E A+
Sbjct: 199 DQERGG--RTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVP--DTVVEPALKAALK 254
Query: 1139 IYRLMDDK--LVPDDDYWGKIPKCSLLQPKEVLVFDFGS-EVYVWHGKEVTLAQRKIAFQ 1195
+Y + D + LV + + + LL ++ + D G ++YVW GK+ ++K A
Sbjct: 255 LYHVSDSEGNLVVREVATRPLTQ-DLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMS 313
Query: 1196 LAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLD 1255
A +N + + P + Q + E+ +F++ F
Sbjct: 314 HA--------------LNFIKAKQYPPSTQVEVQN-----------DGAESAVFQQLFQK 348
Query: 1256 WTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEG 1315
WT R++ G+ + + +D T M PQ A
Sbjct: 349 WTASNRTS--GLGKTHTVGSVAKVEQVKFDATSMHVKPQVAA------------------ 388
Query: 1316 HDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEH 1375
++ + S V VW I + + + +G F+ GD Y++ + +++ GE
Sbjct: 389 -QQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLI---------GE- 437
Query: 1376 SVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGA---QVQVLQGKEPPCFLQC 1432
K+ + + WQG ++ E SA V LD++ Q++V GKEPP +
Sbjct: 438 ------KQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSI 491
Query: 1433 FQGGMVVHSGRREEEEE-NVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNV 1491
F+G MVV+ G RL+ V+G EV + L S V+
Sbjct: 492 FKGRMVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKT- 550
Query: 1492 NKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWD 1551
++ YLW G +E+ + A+ I + +V + EG EP FW
Sbjct: 551 -QSCCYLWCGKGCSGDEREMAKMVADTISR---------TEKQVVV----EGQEPANFWM 596
Query: 1552 ALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQED 1611
ALG + A LQ+ + PRLF S+ +G F ATE F Q+D
Sbjct: 597 ALGGKAPYANTKRLQEE-NLVITPRLFECSNKTGRFLATEIP------------DFNQDD 643
Query: 1612 LYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGK-NL 1670
L + +FL+D +V+ W G E ++K+A T +Y K +
Sbjct: 644 L---EEDDVFLLDVWDQVFFWIGKHANEE------------EKKAAATTAQEYLKTHPSG 688
Query: 1671 KKPAPKSYLIHAGLEPLTFTNMFPSWE------------------HREDIAEITEMDTEV 1712
+ P ++ G EP TFT F +W+ + D ++IT T
Sbjct: 689 RDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQITAEVTSP 748
Query: 1713 SNQITLVEDVLAKLCKTIYPLADLLARP---LPEGVDPLKLEIYLTDEDFEFALDMTRDE 1769
+ L+ I+PL L+ +P LPEGVDP + E +L+ EDF A MT
Sbjct: 749 KVDVFNANSNLSSGPLPIFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAA 808
Query: 1770 YNALPAWKQVNLKKAKGLF 1788
++ALP WKQ NLKK KGLF
Sbjct: 809 FSALPRWKQQNLKKEKGLF 827
Score = 73.2 bits (178), Expect = 2e-12
Identities = 90/384 (23%), Positives = 154/384 (40%), Gaps = 58/384 (15%)
Query: 1323 ITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGK 1382
IT+ + +W I +P + G F +GD Y++ + S H
Sbjct: 14 ITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYII---LAIHKTASSLSYDIH------- 63
Query: 1383 EKCVYFFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVV 1439
+W G+ S++ E+G +A+ T ++D+ R Q + +QG E F F+ G+V+
Sbjct: 64 ------YWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVI 117
Query: 1440 HSG----RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKAL 1495
G + E N RL V+G+ V +E++ +R + +L++ K L
Sbjct: 118 RKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSF---NRGDVFLLDLGK-L 173
Query: 1496 IYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDAL 1553
I W+G ++ + G T A +I++Q E G + V E + S L L
Sbjct: 174 IIQWNGPESTRMERLRGMTLAKEIRDQ---ERGGRTYVGVVDGENELASPKLMEVMNHVL 230
Query: 1554 G-RRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDL 1612
G RR+ KA + A +L+ +S S G+ E ++S ED
Sbjct: 231 GKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLS-----HEDC 285
Query: 1613 YSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKK 1672
Y Q L ++Y+W+G E ++K AM L + K K
Sbjct: 286 YILDQGGL-------KIYVWKGKKANE------------QEKKGAMSHALNFIKAKQY-P 325
Query: 1673 PAPKSYLIHAGLEPLTFTNMFPSW 1696
P+ + + + G E F +F W
Sbjct: 326 PSTQVEVQNDGAESAVFQQLFQKW 349
Score = 60.5 bits (145), Expect = 1e-08
Identities = 69/273 (25%), Positives = 109/273 (39%), Gaps = 52/273 (19%)
Query: 1003 TEQNSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFA 1062
T + +N P RL +Q G + + V RA+ LNS D F+L + CC+LW G+
Sbjct: 503 TSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGC 562
Query: 1063 NVIEKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD 1122
+ E+ A +A I T Q + EG +FW LGG+ Y +
Sbjct: 563 SGDEREMAKMVADTIS--------RTEKQVVVEG-----QEPANFWMALGGKAPYANTKR 609
Query: 1123 PKEDEL-YEAAIIE-TNCIYRLMDDKLVPD---DDYWGKIPKCSLLQPKEVLVFDFGSEV 1177
+E+ L + E +N R + + +PD DD L+ +V + D +V
Sbjct: 610 LQEENLVITPRLFECSNKTGRFLATE-IPDFNQDD----------LEEDDVFLLDVWDQV 658
Query: 1178 YVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIF 1237
+ W GK ++K A A+ +Y + DP E ++ ++G P
Sbjct: 659 FFWIGKHANEEEKKAAATTAQ-------EYLKTHPSGRDP-ETPIIVVKQGHEPP----- 705
Query: 1238 GRLTEHNETILFKEKFLDWTELKRSNEKNPGEL 1270
F FL W K SN K+ +L
Sbjct: 706 ----------TFTGWFLAWDPFKWSNTKSYEDL 728
>gi|94721268 villin-like protein [Homo sapiens]
Length = 856
Score = 162 bits (410), Expect = 3e-39
Identities = 206/842 (24%), Positives = 314/842 (37%), Gaps = 194/842 (23%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
LL IKGR+HV VE ++ N GD FLL W G ++ EKA+ L ++
Sbjct: 137 LLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALTYSLR 196
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKL----LGGQTSYQSAGDPKED-ELYEAAI 1133
+ G RA + G+ A D ++ LG + A P +D + A
Sbjct: 197 DRERGGGRA------QIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKAN 250
Query: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCS--LLQPKEVLVFDFGS-EVYVWHGKEVTLAQR 1190
+ +Y D +V + P + LLQ ++ + D G ++YVW G+ +L +R
Sbjct: 251 VRLYHVYEKGKDLVVLEL----ATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQER 306
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K AF A + +G P + + + E+ FK
Sbjct: 307 KAAFSRAVGFI-------------------------QAKGYPTYTNVEVVNDGAESAAFK 341
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F W+E +R N+K G D VK DV ++ + P+ A
Sbjct: 342 QLFRTWSEKRRRNQKLGGR------DKSIHVKL-DVGKLHTQPKLAA------------- 381
Query: 1311 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1370
R + S V+VW I + + + GQ G+ Y+V + +
Sbjct: 382 ------QLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTY--------- 426
Query: 1371 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERGA---QVQVLQGKEPP 1427
+ G+ + + + WQG +T E ELD G Q V G EPP
Sbjct: 427 -------QRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPP 479
Query: 1428 CFLQCFQGGMVVHSGRREEEEENVQ-SEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1486
FL FQG +V+ R + S RL+ V+G +EV SSL S S
Sbjct: 480 HFLAIFQGQLVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNS--SD 537
Query: 1487 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1546
+ L V ++ YLW G +E+ R I S+ EG EP
Sbjct: 538 IFLLVTASVCYLWFGKGCNGDQREMARVVVTVI-------------SRKNEETVLEGQEP 584
Query: 1547 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 1606
FW+ALG R + L + +F PRLF SS G E +
Sbjct: 585 PHFWEALGGRAPYPSNKRLPEEVP-SFQPRLFECSSHMGCLVLAEVGF------------ 631
Query: 1607 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 1666
F QEDL + + L+D E++LW G AS+ K A+ +Y K
Sbjct: 632 FSQEDL---DKYDIMLLDTWQEIFLWLG--------------EAASEWKEAVAWGQEYLK 674
Query: 1667 GKNL-KKPAPKSYLIHAGLEPLTFTNMFPSWE---------HREDI-------AEITEMD 1709
+ PA L+ G EP TF F +W+ H+E + + I+E+
Sbjct: 675 THPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGSPAAASTISEIT 734
Query: 1710 TEVSN---------------------------QITLVEDVLAKLCKTIYPLADLLA---- 1738
EV+N + LV + +T ++ A
Sbjct: 735 AEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSSSVSSTSATING 794
Query: 1739 ------------RPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKG 1786
LPEGVDP + E YL+D DF+ +++E+ ++ W+Q KK G
Sbjct: 795 GLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMATWRQRQEKKQLG 854
Query: 1787 LF 1788
F
Sbjct: 855 FF 856
Score = 62.0 bits (149), Expect = 5e-09
Identities = 68/299 (22%), Positives = 123/299 (41%), Gaps = 58/299 (19%)
Query: 922 HKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLN----VAFM----ESKRMKVEKMS 973
H++ V PKR Q L A L YT QRL + ++ ++ ++E ++
Sbjct: 402 HRQPVDPKRHGQ--------LCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALN 453
Query: 974 SNSNFSEVTLAGLASKEN-------------FSNVSLRSVNLTEQNSNNSAVPYKRLMLL 1020
SN+ +V G+ +E+ F + + + RL +
Sbjct: 454 SNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSASTTRLFQV 513
Query: 1021 QIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTK 1080
Q + +T V RAS+LNS D FLL++ C+LW G+ N ++ A + T+I K
Sbjct: 514 QGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRK 573
Query: 1081 RELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD-PKEDELYEAAIIETN-- 1137
E +T+ EG FW+ LGG+ Y S P+E ++ + E +
Sbjct: 574 NE--------ETVLEG-----QEPPHFWEALGGRAPYPSNKRLPEEVPSFQPRLFECSSH 620
Query: 1138 --CIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQRKIAF 1194
C+ L + +D L ++++ D E+++W G+ + + +A+
Sbjct: 621 MGCLV-LAEVGFFSQED----------LDKYDIMLLDTWQEIFLWLGEAASEWKEAVAW 668
>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
Length = 782
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 189 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 249 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 299
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 300 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 356 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 390
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 391 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 437
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 438 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 480
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 481 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 533 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 593 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 636
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 637 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 683
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 684 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 733
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 734 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 764
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 68 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 113
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 114 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 172
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 173 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 227
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 228 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 280
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 281 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 330
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 331 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 375
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 376 QVSVLPEGGETPL-FKQFFKNW 396
>gi|38044288 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083782 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 336 QVSVLPEGGETPL-FKQFFKNW 356
>gi|189083780 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 336 QVSVLPEGGETPL-FKQFFKNW 356
>gi|189083778 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083776 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083774 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|189083772 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 139 bits (349), Expect = 3e-32
Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G ++ EEG ++LG + + + + E +AA +
Sbjct: 198 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 248
Query: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190
+Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R
Sbjct: 249 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A I +D P++ Q L E ET LFK
Sbjct: 305 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 339
Query: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
+ F +W + +++ L+ H + + +P A T+ + +
Sbjct: 340 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 386
Query: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369
G+ + G ++Q +W I + + + GQF+ GD+Y++ + +
Sbjct: 387 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 429
Query: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426
R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP
Sbjct: 430 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484
+ F G M+++ G E + + RL+ VR +EV +L S
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544
+ V+ + A YLW G A + ++ G ++ P++ EGS
Sbjct: 542 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 585
Query: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604
EP GFW+ALG + L+D PRLF S+ G F V+
Sbjct: 586 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 632
Query: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662
+P +QEDL + + L+D +V++W G E + T + + K +ET
Sbjct: 633 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 682
Query: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
N + P + ++ G EP +F F W+
Sbjct: 683 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 713
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ +W + +FD +P G F GDAYV+ V G+ Q H
Sbjct: 17 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439
+W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V
Sbjct: 63 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 121
Query: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499
SG + V + RL+ V+G V EV S + ++ N I+ W
Sbjct: 122 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 176
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + + + + I++ S + +H +EG+EP LG +
Sbjct: 177 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 229
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
D +D + A +L+ +S+ +G + + V PF Q L S
Sbjct: 230 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 279
Query: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674
F++D+ + +++W+G + +RK+A++T + + K
Sbjct: 280 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 324
Query: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696
S L G PL F F +W
Sbjct: 325 QVSVLPEGGETPL-FKQFFKNW 345
>gi|162951877 scinderin isoform 1 [Homo sapiens]
Length = 715
Score = 135 bits (339), Expect = 5e-31
Identities = 160/703 (22%), Positives = 293/703 (41%), Gaps = 154/703 (21%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
LL +KGRR V+ V + N GDCF++ + W G N E+ KA+++AT I+
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138
G + + +EEG + K+LG + GD +D + + + +
Sbjct: 199 YNERKG--RSELIVVEEG-----SEPSELIKVLGEKPELPDGGD-DDDIIADISNRKMAK 250
Query: 1139 IYRLMDDK------LVPDDDYWGKIPKCSLLQPKEVLVFDFGS--EVYVWHGKEVTLAQR 1190
+Y + D +V +++ + ++L +E + D G+ +++VW GK+ +R
Sbjct: 251 LYMVSDASGSMRVTVVAEENPF----SMAMLLSEECFILDHGAAKQIFVWKGKDANPQER 306
Query: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250
K A + A+ +N I L G ET +FK
Sbjct: 307 KAAMKTAEEFLQQMNYSKNTQIQVLPEG-------------------------GETPIFK 341
Query: 1251 EKFLDWTELKRSNEKN----PGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNV 1306
+ F DW + +S+ ++AQ K+ P +D +++ S PQ A
Sbjct: 342 QFFKDWRDKDQSDGFGKVYVTEKVAQIKQIP------FDASKLHSSPQMAA--------- 386
Query: 1307 GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTA 1366
+ S V++W + ++ + S G+F+ GD Y++ + +
Sbjct: 387 ----------QHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY----- 431
Query: 1367 VGSRQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQG 1423
+G+ + + WQG ++T E TSA +TV+LD G Q++V QG
Sbjct: 432 ----PRGQ-----------IIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQG 476
Query: 1424 KEPPCFLQCFQGG--MVVHSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLR 1481
KEP L F+ ++ +G ++ + RL+ VR + ++EV +SL
Sbjct: 477 KEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLN 536
Query: 1482 SRTSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECD 1541
S + VL + + Y+W VG+ A+ + ++ A + + I
Sbjct: 537 S-NDVFVLKLPQNSGYIW-----------VGKGASQEEEKGAEYVASVLKCKTLRI---Q 581
Query: 1542 EGSEPLGFWDALGRRDRKAYDCM-LQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPS 1600
EG EP FW++LG +K Y L + + + PRL+ S+ +G F
Sbjct: 582 EGEEPEEFWNSLG--GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRF------------- 626
Query: 1601 VVSSMP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAM 1658
V+ +P F Q+DL + + L+D ++++W G N++ ++K ++
Sbjct: 627 VIEEIPGEFTQDDL---AEDDVMLLDAWEQIFIWIG--KDANEV----------EKKESL 671
Query: 1659 ETVLQYCK----GKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697
++ Y + G++ + P +I G EP TFT F W+
Sbjct: 672 KSAKMYLETDPSGRDKRTPI---VIIKQGHEPPTFTGWFLGWD 711
Score = 64.7 bits (156), Expect = 8e-10
Identities = 91/387 (23%), Positives = 150/387 (38%), Gaps = 68/387 (17%)
Query: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
+ VW I + + +P+ + G F+ GDAY+V + TA SR H
Sbjct: 19 LQVWRIEKLELVPVPQSAHGDFYVGDAYLV-----LHTAKTSRGFTYH-----------L 62
Query: 1388 FFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSGRR 1444
FW G+ + E +A+ TV++D+ G Q + LQG E F+ F+GG+ +G
Sbjct: 63 HFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGV 122
Query: 1445 EEEEENVQSE----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLW 1499
+V + RL V+G V EV S ++ L IY W
Sbjct: 123 ASGLNHVLTNDLTAKRLLHVKGRRVVRAT--EVPLSWDSFNKGDCFIIDLGTE---IYQW 177
Query: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556
G + R AN++ S + + +EGSEP LG +
Sbjct: 178 CGSSCNKYE----RLKANQVATGIRYNERKGRSELIVV---EEGSEPSELIKVLGEKPEL 230
Query: 1557 -DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSA 1615
D D ++ D + A +L+++S +SG R V PF L S
Sbjct: 231 PDGGDDDDIIADISNRKMA-KLYMVSDASGSM---------RVTVVAEENPFSMAMLLS- 279
Query: 1616 PQPALFLVDN--HHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKP 1673
F++D+ ++++W+G + +RK+AM+T ++ + N K
Sbjct: 280 --EECFILDHGAAKQIFVWKG------------KDANPQERKAAMKTAEEFLQQMNYSKN 325
Query: 1674 APKSYLIHAGLEPLTFTNMFPSWEHRE 1700
L G P+ F F W ++
Sbjct: 326 TQIQVLPEGGETPI-FKQFFKDWRDKD 351
>gi|4503743 flightless I homolog [Homo sapiens]
Length = 1269
Score = 107 bits (266), Expect = 1e-22
Identities = 172/745 (23%), Positives = 290/745 (38%), Gaps = 171/745 (22%)
Query: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
+ ++ G+++++ V + ++L+ FLL ++W G A + KA A I
Sbjct: 621 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKIN 680
Query: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE-----DELYEAAI 1133
G I + +G +FW+ LGG+ S P++ +LY+ +
Sbjct: 681 KNERKG--KAEITLLVQG-----QELPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGL 733
Query: 1134 ----IETNCI-YRL-MDDKLVPDDDYWGKIPKC-SLLQPKEVLVFDFGSEVYVWHGKEVT 1186
+E I Y+L ++ K P + ++ SLL + V + D S+V++W G++
Sbjct: 734 GLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSP 793
Query: 1187 LAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNET 1246
R A +L + L C L RP A R E E
Sbjct: 794 RLVRAAALKLGQEL-------------------CGML------HRPRHATVSRSLEGTEA 828
Query: 1247 ILFKEKFLDWTEL-----KRSNE---KNPG------ELAQHKEDPRTDVKAYDVTRMVSM 1292
+FK KF +W ++ R+ E ++PG A+ K+ + D+ A + R M
Sbjct: 829 QVFKAKFKNWDDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPM 888
Query: 1293 PQTTAGTILDGVNV---GRGYGLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQF 1349
A +++ N G ++EG ++RLP++ G F
Sbjct: 889 SLAEAEQLMEEWNEDLDGMEGFVLEGKK--------------------FARLPEEEFGHF 928
Query: 1350 HEGDAYVVKWKFMVSTAVGSRQKGE-HSVRAAGKE-----------------KCVYFFWQ 1391
+ D YV ++ V +K E +A GKE +C+ +FWQ
Sbjct: 929 YTQDCYVFLCRYWVPVEYEEEEKKEDKEEKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQ 988
Query: 1392 GRHST---------VSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSG 1442
GR ++ +K +L +L+ V++ Q +E P FL F+ ++H G
Sbjct: 989 GREASNMGWLTFTFSLQKKFESLFPGKLE-----VVRMTQQQENPKFLSHFKRKFIIHRG 1043
Query: 1443 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVAC----HCSSLRSRTSMVVLNV------N 1492
+R+ + Q LY +R G+ L C SSL + +L V N
Sbjct: 1044 KRKAVQGAQQPS--LYQIR----TNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDN 1097
Query: 1493 KALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLG-FWD 1551
+ ++Y W G + ++ N + + S SK I +EG EP FW
Sbjct: 1098 QGIVYAWVGRASDPDEAKLAEDILNTMFDT--------SYSKQVI---NEGEEPENFFWV 1146
Query: 1552 ALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQED 1611
+G +K YD D + RLF S+ G FA TE F Q+D
Sbjct: 1147 GIGA--QKPYD----DDAEYMKHTRLFRCSNEKGYFAVTE-----------KCSDFCQDD 1189
Query: 1612 LYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLK 1671
L + L+DN EVY+W G + +I S + A + +Q+ + K +
Sbjct: 1190 L---ADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLK---------ACQVYIQHMRSKEHE 1237
Query: 1672 KPAPKSYLIHAGLEPLTFTNMFPSW 1696
+P + L+ G E FT F +W
Sbjct: 1238 RPR-RLRLVRKGNEQHAFTRCFHAW 1261
Score = 51.2 bits (121), Expect = 9e-06
Identities = 58/232 (25%), Positives = 92/232 (39%), Gaps = 34/232 (14%)
Query: 1330 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1389
+W I F + + G+F+E D Y+V F+ + G ++
Sbjct: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDS---------------GSLNWEIYY 547
Query: 1390 WQGRHSTVSEKGTSALMTVELDEERGAQVQVLQ---GKEPPCFLQCFQGGMVVHSGRREE 1446
W G +T+ +K SA+ V L GA+ + ++ G E FLQ F + G
Sbjct: 548 WIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTAS 607
Query: 1447 ---EEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKAL-IYLWHGC 1502
E+ R+Y V G+ ++ L V +SL R V +++ L IY+W G
Sbjct: 608 GFYTVEDTHYVTRMYRVYGKKNIK--LEPVPLKGTSLDPR---FVFLLDRGLDIYVWRGA 662
Query: 1503 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG 1554
+A + R A KI + K I +G E FW+ALG
Sbjct: 663 QATLSSTTKARLFAEKINKN-------ERKGKAEITLLVQGQELPEFWEALG 707
Score = 40.0 bits (92), Expect = 0.020
Identities = 59/258 (22%), Positives = 100/258 (38%), Gaps = 62/258 (24%)
Query: 973 SSNSNFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVP-YKRLMLLQIKGRRHVQ-- 1029
+SN + T + E+ L V +T+Q N + +KR ++ R+ VQ
Sbjct: 992 ASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAVQGA 1051
Query: 1030 ----------------TRLVEPR--ASALNSGDCFLLLSPH-------CCFLWVGEFANV 1064
TR ++ +S LNS CF+L P + WVG A+
Sbjct: 1052 QQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGR-ASD 1110
Query: 1065 IEKAKASE--LATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGD 1122
++AK +E L T+ T Q I EG FW +G Q Y
Sbjct: 1111 PDEAKLAEDILNTMFDTSYSK-------QVINEGEEPENF----FWVGIGAQKPYDD--- 1156
Query: 1123 PKEDELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSL-----LQPKEVLVFDFGSEV 1177
+A ++ ++R ++K Y+ KCS L ++++ D G EV
Sbjct: 1157 -------DAEYMKHTRLFRCSNEK-----GYFAVTEKCSDFCQDDLADDDIMLLDNGQEV 1204
Query: 1178 YVWHGKEVTLAQRKIAFQ 1195
Y+W G + + + K++ +
Sbjct: 1205 YMWVGTQTSQVEIKLSLK 1222
Score = 34.7 bits (78), Expect = 0.85
Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 33/160 (20%)
Query: 1044 DCFLLLSPHC---------CFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQTIE 1094
DC+++L + W+G A + +KA ++ A ++ CR T+
Sbjct: 526 DCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECR-----TVR 580
Query: 1095 EGINTHTHAAKDFWKLLGGQTSYQSAGDPK-----EDELYEAAIIETNCIYRLMDDKLVP 1149
E + + ++F ++ SY G ED Y + +Y + KL P
Sbjct: 581 EEMGDES---EEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYR---VYGKKNIKLEP 634
Query: 1150 DDDYWGKIP-KCSLLQPKEVLVFDFGSEVYVWHGKEVTLA 1188
+P K + L P+ V + D G ++YVW G + TL+
Sbjct: 635 -------VPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLS 667
>gi|14916473 scinderin isoform 2 [Homo sapiens]
Length = 468
Score = 106 bits (265), Expect = 2e-22
Identities = 125/555 (22%), Positives = 229/555 (41%), Gaps = 136/555 (24%)
Query: 1161 SLLQPKEVLVFDFGS--EVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPG 1218
++L +E + D G+ +++VW GK+ +RK A + A+ +N I L G
Sbjct: 28 AMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEG 87
Query: 1219 ECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKN----PGELAQHK 1274
ET +FK+ F DW + +S+ ++AQ K
Sbjct: 88 -------------------------GETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIK 122
Query: 1275 EDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEITSVSVDVWHIL 1334
+ P +D +++ S PQ A + S V++W +
Sbjct: 123 QIP------FDASKLHSSPQMAA-------------------QHNMVDDGSGKVEIWRVE 157
Query: 1335 EFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFFWQGRH 1394
++ + S G+F+ GD Y++ + + +G+ + + WQG +
Sbjct: 158 NNGRIQVDQNSYGEFYGGDCYIILYTY---------PRGQ-----------IIYTWQGAN 197
Query: 1395 STVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGG--MVVHSGRREEEEE 1449
+T E TSA +TV+LD G Q++V QGKEP L F+ ++ +G ++ +
Sbjct: 198 ATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQ 257
Query: 1450 NVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCKAQAHTK 1509
RL+ VR + ++EV +SL S + VL + + Y+W
Sbjct: 258 APAPPTRLFQVRRNLASITRIVEVDVDANSLNS-NDVFVLKLPQNSGYIW---------- 306
Query: 1510 EVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCM-LQDP 1568
VG+ A+ + ++ A + + I EG EP FW++LG +K Y L +
Sbjct: 307 -VGKGASQEEEKGAEYVASVLKCKTLRI---QEGEEPEEFWNSLG--GKKDYQTSPLLET 360
Query: 1569 GSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP--FLQEDLYSAPQPALFLVDNH 1626
+ + PRL+ S+ +G F V+ +P F Q+DL + + L+D
Sbjct: 361 QAEDHPPRLYGCSNKTGRF-------------VIEEIPGEFTQDDL---AEDDVMLLDAW 404
Query: 1627 HEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK----GKNLKKPAPKSYLIHA 1682
++++W G N++ ++K ++++ Y + G++ + P +I
Sbjct: 405 EQIFIWIG--KDANEV----------EKKESLKSAKMYLETDPSGRDKRTPI---VIIKQ 449
Query: 1683 GLEPLTFTNMFPSWE 1697
G EP TFT F W+
Sbjct: 450 GHEPPTFTGWFLGWD 464
Score = 54.7 bits (130), Expect = 8e-07
Identities = 50/207 (24%), Positives = 92/207 (44%), Gaps = 36/207 (17%)
Query: 1001 NLTEQNSNNSAVPYKRLMLLQIKGRRHVQTRLVEPR--ASALNSGDCFLLLSP-HCCFLW 1057
N T + + P RL Q++ TR+VE A++LNS D F+L P + ++W
Sbjct: 249 NGTSKKGGQAPAPPTRLF--QVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 306
Query: 1058 VGEFANVIEKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY 1117
VG+ A+ E+ A +A++++ C+ IQ EE ++FW LGG+ Y
Sbjct: 307 VGKGASQEEEKGAEYVASVLK------CKTLRIQEGEE--------PEEFWNSLGGKKDY 352
Query: 1118 QSA------GDPKEDELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVF 1171
Q++ + LY + + + + DD L +V++
Sbjct: 353 QTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDD-----------LAEDDVMLL 401
Query: 1172 DFGSEVYVWHGKEVTLAQRKIAFQLAK 1198
D ++++W GK+ ++K + + AK
Sbjct: 402 DAWEQIFIWIGKDANEVEKKESLKSAK 428
>gi|63252913 gelsolin-like capping protein [Homo sapiens]
Length = 348
Score = 61.6 bits (148), Expect = 7e-09
Identities = 49/227 (21%), Positives = 100/227 (44%), Gaps = 22/227 (9%)
Query: 1006 NSNNSAVPYKRLMLLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVI 1065
+ ++ P L Q+KG+++++ + N+GDCF+L F W G +N++
Sbjct: 126 HKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNIL 185
Query: 1066 EKAKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKE 1125
E+ KA +LA I+ G ++ + +G + ++LG + + + G+P+E
Sbjct: 186 ERNKARDLALAIRDSERQG--KAQVEIVTDG-----EEPAEMIQVLGPKPALKE-GNPEE 237
Query: 1126 DELYEAAIIETNCIYRLMD-------DKLVPDDDYWGKIPKCSLLQPKEVLVFDFG--SE 1176
D + A + +Y++ D K+ + LL + V D G +
Sbjct: 238 DLTADKANAQAAALYKVSDATGQMNLTKVADSSPF-----ALELLISDDCFVLDNGLCGK 292
Query: 1177 VYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPL 1223
+Y+W G++ +R+ A Q+A+ + N + L G +P+
Sbjct: 293 IYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPI 339
Score = 46.2 bits (108), Expect = 3e-04
Identities = 69/320 (21%), Positives = 121/320 (37%), Gaps = 59/320 (18%)
Query: 1330 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1389
VW + + + +++ G F GD+Y+V + +E
Sbjct: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLV-------------------LHNGPEEVSHLHL 63
Query: 1390 WQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREE 1446
W G+ S+ E+G A++ V L+ ER Q + +QG E F+ F G+ G E
Sbjct: 64 WIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVES 123
Query: 1447 EEENVQSE-----WRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVV-LNVNKALIYLWH 1500
+ +LY V+G+ + E A + S + ++ L N I+ W
Sbjct: 124 AFHKTSTGAPAAIKKLYQVKGKKNIRAT--ERALNWDSFNTGDCFILDLGQN---IFAWC 178
Query: 1501 GCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALG----RR 1556
G K+ + R A I++ K + +G EP LG +
Sbjct: 179 GGKSNILERNKARDLALAIRDS-------ERQGKAQVEIVTDGEEPAEMIQVLGPKPALK 231
Query: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616
+ + + D + A L+ +S ++G T+ V S PF E L S
Sbjct: 232 EGNPEEDLTADKANAQ-AAALYKVSDATGQMNLTK---------VADSSPFALELLIS-- 279
Query: 1617 QPALFLVDNH--HEVYLWQG 1634
F++DN ++Y+W+G
Sbjct: 280 -DDCFVLDNGLCGKIYIWKG 298
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 45.8 bits (107), Expect = 4e-04
Identities = 140/729 (19%), Positives = 271/729 (37%), Gaps = 115/729 (15%)
Query: 48 PASPHIGRSNEEEETSDSSLEKQTRSKYCTETSGVHG--DSPYGSGTMDTHSLESKAERI 105
P+ P S ++E TS+ +K+ T SG G +P D L E I
Sbjct: 238 PSQPTTDTSTDKERTSEDMADKEKS----TADSGGEGLETAPKSEEFSD---LPCPVEEI 290
Query: 106 ARYKAERRRQLAEKYGLTLDPEADS-EYLSRYT-KSRKEPDAVEKRGGKSDKQEESSR-- 161
Y E + L D + +S E ++ T K K+PD+ EK K +K+E++ +
Sbjct: 291 KNYTKEHNNLIL----LNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF 346
Query: 162 DASSLYPGTETMGLRTCAGESKDYALHVGDGSSDPEVLLNIENQRRGQELSATRQAHDLS 221
D S T+ + A E + +L L + +N + + + T++ L
Sbjct: 347 DHSKKSEDTQKVKDEKQAKEKEVESLK----------LPSEKNSNKAKTVEGTKEDFSLI 396
Query: 222 PAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQAASRSPSFGDPQL-SPEARPRCTSH 280
+ T D + + V S + ++ S S + ++ S + +
Sbjct: 397 DSDVDGLT------DITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNK 450
Query: 281 SETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLRRLQDRS 340
++T T D E + + + K L+ + D++ ++R ++ A E+ ++R
Sbjct: 451 TKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEK-----EERL 505
Query: 341 LTQPITTEEVVIAATLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLS 400
L + I E++ +A + + K Q +L E SST SL K A ++
Sbjct: 506 LRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEE-----SSTKSLEPKAARIKEVL 560
Query: 401 Q-----PVSKAISTRNRIDTRQRRMNARYQTQ-----PVTLGEVEQVQSGKLIPFSPAVN 450
+ A+S + + D+R N++ + Q TL E + K+
Sbjct: 561 KERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKI-------- 612
Query: 451 TSVSTVASTVAPMYAGDLRTKPPLDHNASATDYKFSSSIENSDSPVRSILKSQAWQPLVE 510
+S+ + K + P R + +S +V+
Sbjct: 613 ---------------------------SSSKELKHVHAKSEPSKPARRLSES---LHVVD 642
Query: 511 GSENKGMLREYGETESKRALTGRDSGMEKYGSFEEAEASYPILNRARE---GDSHKESKY 567
++N+ L E E KR T ME G EE + R + ++ K
Sbjct: 643 ENKNESKL----EREHKRR-TSTPVIME--GVQEETDTRDVKRQVERSEICTEEPQKQKS 695
Query: 568 AVPRRGSLERANPPITHLGDEPKEFSMAKMNAQGNLDLRDRLPFEEKVEVENVMKRKFSL 627
+ L++ + HL K ++ + R++ P E+K+ V++ K
Sbjct: 696 TLKNEKHLKKDDSETPHL----KSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMH 751
Query: 628 RAAEFGEPTSEQTGTAAGKTIAQTTAPVSWKPQDSSEQPQEKLCKNPCAMFAAGEIKTPT 687
+ + E S + G + I + + D +E+ + +N + G+ P
Sbjct: 752 KTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKH--RNERKLSVLGKDGKPV 809
Query: 688 GEGLL---DSPSKTMSIKERLALLKKSGEEDWRNRLSRRQEGGKAPASSLHTQEAGRSLI 744
E ++ ++ K + KER + S E+ SRR K SL +++ G +L
Sbjct: 810 SEYIIKTDENVRKENNKKER----RLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQ 865
Query: 745 KKRVTESRE 753
++ + S +
Sbjct: 866 RRSESYSED 874
>gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 358 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405
>gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Homo
sapiens]
Length = 358
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 311 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 358
>gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 336 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383
>gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 336 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383
>gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 358 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405
>gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/48 (43%), Positives = 29/48 (60%)
Query: 1741 LPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF 1788
LP GVD ++LE +L+ EDF M+ +E+ L WK+ LKK LF
Sbjct: 358 LPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 42.0 bits (97), Expect = 0.005
Identities = 59/288 (20%), Positives = 113/288 (39%), Gaps = 24/288 (8%)
Query: 215 RQAHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAHSSSLQQAASRSPSFGDPQLSPEAR 274
R H S ++ SSS+ S S SS + S + SSS ++S S SF P
Sbjct: 144 RSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKP------H 197
Query: 275 PRCTSHSETPTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKRRSRNTAVEQRLR 334
H E P+ D E + S R+ KS E + + ++ E+ +
Sbjct: 198 KLMKEHKEKPSKDSREHKSAFKEPS--------RDHNKSSKESSKKPKENKPLKEEKIVP 249
Query: 335 RLQDRSLTQPITTEEVVIAATLQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLA 394
++ + +P++ E + L ++ Q K ++ +++ E + + A
Sbjct: 250 KMAFKE-PKPMSKEPKPDSNLLTITSGQD---KKAPSKRPPISDSEELSAKKRKKSSSEA 305
Query: 395 LFNKLSQPVSKAISTRNRIDTRQRRMNARYQTQPVTL-GEVEQVQSGKLIPFSPAVNTSV 453
LF S ++ D +Q + + + V + E + + L PF V+ +
Sbjct: 306 LFKSFSSAPPLILTC--SADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPND 363
Query: 454 STVASTVAPMYAGDLRTKPPLDHNASATDYKFSSSIENSDSPVRSILK 501
S V ++ + +P ++S++ F+ S P+RSI+K
Sbjct: 364 SDVEENISSKSDSE---QPSPASSSSSSSSSFTPSQTRQQGPLRSIMK 408
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1730 IYPLADLLAR-----PLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKA 1784
IYP L+ LP+ VD +LE +L+ E+F+ M+ +E++ L WK+ +LKK
Sbjct: 458 IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKK 517
Query: 1785 KGLF 1788
LF
Sbjct: 518 ALLF 521
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1730 IYPLADLLAR-----PLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKA 1784
IYP L+ LP+ VD +LE +L+ E+F+ M+ +E++ L WK+ +LKK
Sbjct: 468 IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKK 527
Query: 1785 KGLF 1788
LF
Sbjct: 528 ALLF 531
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1730 IYPLADLLAR-----PLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKA 1784
IYP L+ LP+ VD +LE +L+ E+F+ M+ +E++ L WK+ +LKK
Sbjct: 496 IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKK 555
Query: 1785 KGLF 1788
LF
Sbjct: 556 ALLF 559
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1730 IYPLADLLAR-----PLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKA 1784
IYP L+ LP+ VD +LE +L+ E+F+ M+ +E++ L WK+ +LKK
Sbjct: 509 IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKK 568
Query: 1785 KGLF 1788
LF
Sbjct: 569 ALLF 572
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1730 IYPLADLLAR-----PLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKA 1784
IYP L+ LP+ VD +LE +L+ E+F+ M+ +E++ L WK+ +LKK
Sbjct: 548 IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKK 607
Query: 1785 KGLF 1788
LF
Sbjct: 608 ALLF 611
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,824,511
Number of Sequences: 37866
Number of extensions: 3141941
Number of successful extensions: 8757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 8147
Number of HSP's gapped (non-prelim): 555
length of query: 1788
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1671
effective length of database: 13,817,196
effective search space: 23088534516
effective search space used: 23088534516
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.