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Search of human proteins with 110347441
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
(464 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 946 0.0
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 906 0.0
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 753 0.0
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 752 0.0
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 721 0.0
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 719 0.0
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 719 0.0
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 625 e-179
gi|4504023 glycine receptor, beta [Homo sapiens] 369 e-102
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 293 2e-79
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 293 2e-79
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 289 4e-78
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 288 7e-78
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 286 3e-77
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 285 5e-77
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 278 6e-75
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 276 4e-74
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 275 6e-74
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 275 6e-74
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 274 1e-73
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 268 8e-72
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 268 8e-72
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 268 8e-72
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 266 2e-71
gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Hom... 266 2e-71
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 946 bits (2445), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
Sbjct: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
Query: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
Sbjct: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
Query: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
Sbjct: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
Query: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
Sbjct: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
Query: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
Sbjct: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
Query: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA 360
SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
Sbjct: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA 360
Query: 361 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 420
FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
Sbjct: 361 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 420
Query: 421 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 464
FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
Sbjct: 421 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 464
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 906 bits (2342), Expect = 0.0
Identities = 449/464 (96%), Positives = 449/464 (96%), Gaps = 15/464 (3%)
Query: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
Sbjct: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
Query: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
Sbjct: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
Query: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
Sbjct: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
Query: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
Sbjct: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
Query: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
Sbjct: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
Query: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA 360
SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNK
Sbjct: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNK--- 357
Query: 361 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 420
DDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
Sbjct: 358 ------------DDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 405
Query: 421 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 464
FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
Sbjct: 406 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 449
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 753 bits (1943), Expect = 0.0
Identities = 371/454 (81%), Positives = 403/454 (88%), Gaps = 12/454 (2%)
Query: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Query: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
Query: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
Query: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
Query: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
Query: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDD 374
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ L F +D
Sbjct: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPM-LNLF-----QED 363
Query: 375 EVRESRFSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKI 428
E E RF+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKI
Sbjct: 364 EAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKI 423
Query: 429 DTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQ 462
D ISR FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 424 DKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 752 bits (1942), Expect = 0.0
Identities = 370/454 (81%), Positives = 401/454 (88%), Gaps = 20/454 (4%)
Query: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Query: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
Query: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
Query: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
Query: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
Query: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDD 374
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ E D
Sbjct: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKE--------------D 355
Query: 375 EVRESRFSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKI 428
E E RF+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKI
Sbjct: 356 EAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKI 415
Query: 429 DTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQ 462
D ISR FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 416 DKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ 449
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 721 bits (1860), Expect = 0.0
Identities = 354/434 (81%), Positives = 383/434 (88%), Gaps = 13/434 (2%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMG 389
ALLEYAAVNFVSRQHKE LR RR++K + + +D RESRF+F+ YGMG
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------------EDVTRESRFNFSGYGMG 378
Query: 390 PCLQAKDGMTPKG-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYW 448
CLQ KDG K P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW
Sbjct: 379 HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYW 438
Query: 449 VIYKILRHEDIHQQ 462
+ YKI+RHED+H++
Sbjct: 439 ITYKIIRHEDVHKK 452
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 719 bits (1855), Expect = 0.0
Identities = 352/434 (81%), Positives = 382/434 (88%), Gaps = 13/434 (2%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMG 389
ALLEYAAVNFVSRQHKE LR RR++K + + +D RESRF+F+ YGMG
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------------EDVTRESRFNFSGYGMG 378
Query: 390 PCLQAKDGMTPKG-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYW 448
CLQ KDG K P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW
Sbjct: 379 HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYW 438
Query: 449 VIYKILRHEDIHQQ 462
+ YKI+RHED+H++
Sbjct: 439 ITYKIIRHEDVHKK 452
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 719 bits (1855), Expect = 0.0
Identities = 352/434 (81%), Positives = 382/434 (88%), Gaps = 13/434 (2%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMG 389
ALLEYAAVNFVSRQHKE LR RR++K + + +D RESRF+F+ YGMG
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------------EDVTRESRFNFSGYGMG 378
Query: 390 PCLQAKDGMTPKG-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYW 448
CLQ KDG K P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW
Sbjct: 379 HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYW 438
Query: 449 VIYKILRHEDIHQQ 462
+ YKI+RHED+H++
Sbjct: 439 ITYKIIRHEDVHKK 452
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 625 bits (1613), Expect = e-179
Identities = 314/409 (76%), Positives = 348/409 (85%), Gaps = 19/409 (4%)
Query: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
LL +A +E S S PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS
Sbjct: 22 LLRVALAKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 81
Query: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
F SI +TTMDYRVN+FLRQ+WNDPRL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGAN
Sbjct: 82 FSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 141
Query: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
FHEVTTDNKLLRIFKNGNVLYSIRLTL LSC MDLKNFPMD+QTC MQLESFGYTM DL+
Sbjct: 142 FHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLV 201
Query: 201 FEWQDEAP-VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQ 259
FEW ++AP VQVAEGLTLPQF+L++EKDL CTKHYNTGKFTCIEV+FHLERQMGYYLIQ
Sbjct: 202 FEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQ 261
Query: 260 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 319
MYIPSLLIVILSWVSFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIW
Sbjct: 262 MYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 321
Query: 320 MAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRES 379
MAVCLLFVF+ALLEYAA+NFVSRQHKE +R RR+++ + LE +D ++ES
Sbjct: 322 MAVCLLFVFAALLEYAAINFVSRQHKEFIRLRRRQRRQ----RLE--------EDIIQES 369
Query: 380 RFSFTAYGMGPCLQAKDGMTPKG-----PNHPVQVMPKSPDEMRKVFID 423
RF F YG+G CLQA+DG +G P P ++ + + RK+++D
Sbjct: 370 RFYFRGYGLGHCLQARDGGPMEGSGIYSPQPPAPLL-REGETTRKLYVD 417
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 369 bits (948), Expect = e-102
Identities = 217/471 (46%), Positives = 289/471 (61%), Gaps = 56/471 (11%)
Query: 25 LVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSI 84
L ++++ +R S S+ L++L+ YD RIRPNFKG PV+V NIFINSFGSI
Sbjct: 38 LCPSQQSAEDLARVPANSTSNILNRLL---VSYDPRIRPNFKGIPVDVVVNIFINSFGSI 94
Query: 85 AETTMDYRVNIFLRQKWNDPRLAY-SEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFH 142
ETTMDYRVNIFLRQKWNDPRL S++ D+L +DP+M +WKPDLFFANEK ANFH
Sbjct: 95 QETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFH 154
Query: 143 EVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFE 202
+VT +N LL IF++G+VL S+RL++TLSCP+DL FPMD Q C MQLESFGYT +DL F
Sbjct: 155 DVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
Query: 203 WQDEAPVQVAEGLTLPQFLLKEEKDLRY--CTKHY-NTGKFTCIEVRFHLERQMGYYLIQ 259
WQ PVQ+ E + LPQF +K+E D+ Y CTK+Y TG +TC+EV F L RQ+G+Y++
Sbjct: 215 WQSGDPVQL-EKIALPQFDIKKE-DIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMG 272
Query: 260 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 319
+Y P+LLIV+LSW+SFWIN DA+ ARV LGI +VL++ ++ + A LPKVSYVKA+D+W
Sbjct: 273 VYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVW 332
Query: 320 MAVCLLFVFSALLEYAAV----NFVSRQHKELLRFRR-----------KRKN-------- 356
+ CLLF F++L+EYA V N R E R + +KN
Sbjct: 333 LIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTP 392
Query: 357 ---KTEAFALEKFYRFSDMDDEVRESRFS-------------FTAYGMGPCLQAKDGMTP 400
T + + ++R + FS + YG ++ +G+
Sbjct: 393 VHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKP--IEVNNGLGK 450
Query: 401 KGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ + P P V AK+ID +RA FP FL FN+ YW IY
Sbjct: 451 SQAKNNKKPPPAKP-----VIPTAAKRIDLYARALFPFCFLFFNVIYWSIY 496
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 293 bits (750), Expect = 2e-79
Identities = 169/436 (38%), Positives = 252/436 (57%), Gaps = 36/436 (8%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T
Sbjct: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEE 225
T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 226 KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPAR 285
+ L + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 286 VALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV----- 340
VALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 341 SRQHKELLRFRRKRKN---KTEA-----------FALEKFYRFSDMDDEVRESRFSFTAY 386
++ K+L K KN K+E+ +LE +++ + ++R S ++
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 387 GMGPCLQAKDGMTPKG----------PNHPVQVMPKSPDEMRKV-FIDRAKKIDTISRAC 435
K M +G P+ + +S K+ + ID SR
Sbjct: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455
Query: 436 FPLAFLIFNIFYWVIY 451
FP F +FN+ YW+ Y
Sbjct: 456 FPFTFSLFNLVYWLYY 471
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 293 bits (750), Expect = 2e-79
Identities = 169/436 (38%), Positives = 252/436 (57%), Gaps = 36/436 (8%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T
Sbjct: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEE 225
T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 226 KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPAR 285
+ L + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 286 VALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV----- 340
VALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 341 SRQHKELLRFRRKRKN---KTEA-----------FALEKFYRFSDMDDEVRESRFSFTAY 386
++ K+L K KN K+E+ +LE +++ + ++R S ++
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 387 GMGPCLQAKDGMTPKG----------PNHPVQVMPKSPDEMRKV-FIDRAKKIDTISRAC 435
K M +G P+ + +S K+ + ID SR
Sbjct: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455
Query: 436 FPLAFLIFNIFYWVIY 451
FP F +FN+ YW+ Y
Sbjct: 456 FPFTFSLFNLVYWLYY 471
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 289 bits (739), Expect = 4e-78
Identities = 171/459 (37%), Positives = 248/459 (54%), Gaps = 52/459 (11%)
Query: 34 ARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRV 93
A S + P + S + + GYD R+RP+F GPPV+V I + S ++E MDY +
Sbjct: 25 AHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTL 84
Query: 94 NIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRI 153
++ +Q W D RL+YS P + L LD + D +W PD +F N+K + H VT N+++R+
Sbjct: 85 TMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL 143
Query: 154 FKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVA 212
+G VLY +R+T T +C MDL+ +P+D Q C +++ES+GYT +D+ F W E V
Sbjct: 144 HPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGV 203
Query: 213 EGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSW 272
+ LPQF + + K + + + TG + + + F L+R +GY+++Q Y+PS LI ILSW
Sbjct: 204 NKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSW 262
Query: 273 VSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALL 332
VSFWIN DA+ ARVALGITTVLTMTT S+ R +LPK+ YVKAIDI++ C +FVF ALL
Sbjct: 263 VSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALL 322
Query: 333 EYAAVNFV-----------SRQHKELLRFRRKRKNKTEAFA--------LE--------- 364
EYA VN++ S+Q + + NK + A LE
Sbjct: 323 EYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSE 382
Query: 365 ----------KFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKG--PNHPVQVMPK 412
Y + + R+ S AYG + G+ KG Q+ K
Sbjct: 383 VLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRA---LDRHGVPSKGRIRRRASQLKVK 439
Query: 413 SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
PD + ID SR FP+ F +FN+ YW+ Y
Sbjct: 440 IPD------LTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 288 bits (737), Expect = 7e-78
Identities = 174/474 (36%), Positives = 259/474 (54%), Gaps = 47/474 (9%)
Query: 14 FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73
F W L+++ V + + + S D L K GYD R+RP+F GPPV V
Sbjct: 10 FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
Query: 74 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133
NI I S ++E MDY + ++ +Q W D RL+Y+ P + L LD + D +W PD +F
Sbjct: 64 MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
Query: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193
N+K + H VT N+++R+ +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
Query: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250
YT +D+ F W+ D+ V + LPQF + D + TK ++TG + + + F L+
Sbjct: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
Query: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310
R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+
Sbjct: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
Query: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV------SRQHK----------ELLRFRRKR 354
YVKAID+++ C +FVF ALLEYA VN++ RQ K E +R +
Sbjct: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
Query: 355 KNKTEAFALEKFYRFSDMDDE-----VRESRFSFTAYGMGPCLQAKDGMTPK---GPNHP 406
+ E L ++M + + R + AY K G+ P+ G N
Sbjct: 360 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGL-PRHSFGRNAL 418
Query: 407 VQVMPKSPDEMRK---------VFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ + + +R+ + ID SR FP+ F FNI YW+ Y
Sbjct: 419 ERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 286 bits (732), Expect = 3e-77
Identities = 156/421 (37%), Positives = 236/421 (56%), Gaps = 25/421 (5%)
Query: 46 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPR 105
+L L G +GY RP GPPVNV + + S I+E M+Y + +FL Q W D R
Sbjct: 40 WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99
Query: 106 LAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRL 165
L+Y+ + +++L LD +D +W PD F N K A FH+VT +NKL+R+ +G +LYSIR+
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158
Query: 166 TLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKE 224
T T++C MDL +PMD Q C++ LES+GY+ D+++ W + + + + L L QF +
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218
Query: 225 EKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
+ + G+F + + FHL R G Y+IQ Y+PS+L+V +SWVSFWI+ A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278
Query: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNF---VS 341
RV+LGITTVLTMTT +R+SLP+ S +KA+D++ +C +FVF+AL+EYA +F
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYR 338
Query: 342 RQHKELLRFRRKR-----KNKTEAFALEKFYRFSDMDDEVRESRF------SFTAYGMGP 390
++ K ++ R R +N F+L ++ R+ R S+ + G+
Sbjct: 339 KKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVET 398
Query: 391 CLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVI 450
K+G G ++ + D A ID +RA FP AF N+ YW
Sbjct: 399 GETKKEGAARSGGQGGIRARLRPID---------ADTIDIYARAVFPAAFAAVNVIYWAA 449
Query: 451 Y 451
Y
Sbjct: 450 Y 450
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 285 bits (730), Expect = 5e-77
Identities = 176/511 (34%), Positives = 258/511 (50%), Gaps = 83/511 (16%)
Query: 14 FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73
F W L+++ V + + + S D L K GYD R+RP+F GPPV V
Sbjct: 10 FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
Query: 74 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133
NI I S ++E MDY + ++ +Q W D RL+Y+ P + L LD + D +W PD +F
Sbjct: 64 MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
Query: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193
N+K + H VT N+++R+ +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
Query: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250
YT +D+ F W+ D+ V + LPQF + D + TK ++TG + + + F L+
Sbjct: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
Query: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310
R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+
Sbjct: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
Query: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV------SRQHKELLRFRRKRKNKTEAFALE 364
YVKAID+++ C +FVF ALLEYA VN++ RQ K + K +
Sbjct: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
Query: 365 KFYR---------------FSDMDDEVRESRFSFTAYGMGP-------CLQAKDGMTPK- 401
FY+ ++ R + + F+ Y M P L+ K+ M
Sbjct: 360 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE 419
Query: 402 ------GPNHPVQVMPKSPDEMRKVFIDR------------------------------- 424
P + S + RK + R
Sbjct: 420 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP 479
Query: 425 ----AKKIDTISRACFPLAFLIFNIFYWVIY 451
ID SR FP+ F FNI YW+ Y
Sbjct: 480 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 510
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 278 bits (712), Expect = 6e-75
Identities = 162/419 (38%), Positives = 242/419 (57%), Gaps = 22/419 (5%)
Query: 44 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWND 103
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
Query: 104 PRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSI 163
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
Query: 164 RLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLK 223
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W+ + P+ E LL+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWK-KGPLYSVEVPEESSSLLQ 207
Query: 224 EE---KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 280
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Query: 281 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
Query: 341 SRQHKELLRFRRKRKNKTEAFALEKFYRFSD-MDDEV---RESRF----SFTAYGMGPCL 392
+ + + KRK + A + ++ ++ E+ +S++ T+ + P +
Sbjct: 328 TNLQTQ----KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL-PIV 382
Query: 393 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ + +Q P +P + F KID SR FP+AF FN+ YWV+Y
Sbjct: 383 SSSEANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 276 bits (705), Expect = 4e-74
Identities = 150/405 (37%), Positives = 228/405 (56%), Gaps = 19/405 (4%)
Query: 54 TSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD 113
T+GY+ +RPNF G PV + + I S SI+E+ MDY I+LRQ+W D RL + +
Sbjct: 45 TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102
Query: 114 DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPM 173
S LD +++ +W PD + K + HEVT N+L+R+F NG VLY++R+T T++C M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162
Query: 174 DLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QDEAPVQVAEGLTLPQFLLKEEKDLRYCT 232
DL +PMD QTC +QLES+GY ND+ F W + V+ E L L Q+ ++ RY T
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIE-----RYFT 217
Query: 233 ----KHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 288
TG +T + ++F L R + Y++++ Y+PS +V+LSWVSFWI++D+ PAR +
Sbjct: 218 LVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCI 277
Query: 289 GITTVLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKEL 347
G+TTVL+MTT GSR SLP + ++KAID+++ +C FVF ALLEYA ++ S Q
Sbjct: 278 GVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQ---- 333
Query: 348 LRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPV 407
+ K + T+ + + + SF + + +T K +
Sbjct: 334 -QMAAKDRGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFK 392
Query: 408 QVMPKSPDEMRKVF-IDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
V + + F I +D S+ FPL F++ N+FYW Y
Sbjct: 393 FVFREKMGRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 275 bits (703), Expect = 6e-74
Identities = 169/459 (36%), Positives = 257/459 (55%), Gaps = 34/459 (7%)
Query: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
Query: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
Query: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
Query: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
Query: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
Query: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ K+
Sbjct: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVV--NDKK 354
Query: 355 KNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQ--AKDGMTPKGPNHPVQVMPK 412
K K Y + + S+ P L +K TP+ P
Sbjct: 355 KEKASVMIQNNAYAVAVANYAPNLSK--------DPVLSTISKSATTPEPNKKP----EN 402
Query: 413 SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P E +K F + KID +SR FP+ F FN+ YW Y
Sbjct: 403 KPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 275 bits (703), Expect = 6e-74
Identities = 169/459 (36%), Positives = 257/459 (55%), Gaps = 34/459 (7%)
Query: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
Query: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
Query: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
Query: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
Query: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
Query: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ K+
Sbjct: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVV--NDKK 354
Query: 355 KNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQ--AKDGMTPKGPNHPVQVMPK 412
K K Y + + S+ P L +K TP+ P
Sbjct: 355 KEKASVMIQNNAYAVAVANYAPNLSK--------DPVLSTISKSATTPEPNKKP----EN 402
Query: 413 SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P E +K F + KID +SR FP+ F FN+ YW Y
Sbjct: 403 KPAEAKKTF-NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 274 bits (700), Expect = 1e-73
Identities = 150/410 (36%), Positives = 236/410 (57%), Gaps = 16/410 (3%)
Query: 53 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP 112
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
Query: 113 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCP 172
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+F +G+VLYS+R+T+T C
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
Query: 173 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEEKDLRYC 231
MD +FP+D QTC ++LES+ YT DL+ W++ + ++ E ++L QFL+++
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
Query: 232 TKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 291
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
Query: 292 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFR 351
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ + R
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE---RKE 381
Query: 352 RKRKNKTEAFALEKFYRFSDMDDEVRESRF-SFTAYGMGPCLQAKD---------GMTPK 401
RK + K + +D ES S Y L ++ G++ +
Sbjct: 382 RKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGE 441
Query: 402 GPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ + K R ID SR FP +++ FN+ YW ++
Sbjct: 442 ANAARKKGLLKGQTGFR--IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 268 bits (685), Expect = 8e-72
Identities = 156/419 (37%), Positives = 238/419 (56%), Gaps = 25/419 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ + P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++RLT
Sbjct: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--DEAPVQVAE-GLTLPQF-LL 222
+ CPM L++FPMDV C ++ S+ YT ++++ W V+VA+ G L Q+ LL
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 247 GHVVGTEIIRS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 304
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 305 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 364
Query: 343 -----QHKELLRFRRKRKNKTEAFALEKFYRFSDMD-----DEVRESRFSFTAYGMGPCL 392
+ K++ +K A A + F+ + + +++ FS + G P
Sbjct: 365 RSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSA 424
Query: 393 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ + VQ SP E + + K+D ISR FP+ F IFN+ YW Y
Sbjct: 425 SSTPTIIASPKATYVQ---DSPTETKT--YNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 268 bits (685), Expect = 8e-72
Identities = 162/414 (39%), Positives = 237/414 (57%), Gaps = 26/414 (6%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT- 338
Query: 343 QHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKD----GM 398
+R ++ EK + D + + + ++ TA P L D +
Sbjct: 339 --------KRGYAWDGKSVVPEKPKKVKDPLIK-KNNTYAPTATSYTPNLARGDPGLATI 389
Query: 399 TPKGPNHPVQVMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
P +V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 390 AKSATIEPKEVKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 266 bits (681), Expect = 2e-71
Identities = 151/410 (36%), Positives = 233/410 (56%), Gaps = 22/410 (5%)
Query: 50 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS 109
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
Query: 110 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTL 169
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++RLT++
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
Query: 170 SCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD---EAPVQVAEGLTLPQFLLKEEK 226
CPM L++FPMD C ++ S+ Y +++++ W + ++ V +G L Q+ L +
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 227 DLRYCTKHYNT--GKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
T++ +T G++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PA
Sbjct: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
Query: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH 344
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR- 347
Query: 345 KELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPN 404
+ K EA ++K + + +S +FT M TP G +
Sbjct: 348 ----GWAWDGKKALEAAKIKK-----KREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTS 398
Query: 405 HPVQVMPKSPDEM---RKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ V K +E K + KID +SR FP+ F FN+ YW Y
Sbjct: 399 NTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Homo
sapiens]
Length = 467
Score = 266 bits (681), Expect = 2e-71
Identities = 137/402 (34%), Positives = 235/402 (58%), Gaps = 14/402 (3%)
Query: 58 DARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLD 117
D +RP F G PV V ++ + S SI+ET MD+ + +LR W D RL++ + S+
Sbjct: 71 DFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMT 130
Query: 118 LDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKN 177
D + IW PD+FF + K + H+ T +N +LR+ +GNVL S+R+T++ C MD
Sbjct: 131 FDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSR 190
Query: 178 FPMDVQTCIMQLESFGYTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYN 236
FP+D Q C ++LES+ Y +DL+ W+ + E ++L QF +++ + +
Sbjct: 191 FPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSS 250
Query: 237 TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTM 296
TG + + + F L R + ++++Q Y P++L+V+LSWVSFWI+ A PARV+LGITTVLTM
Sbjct: 251 TGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTM 310
Query: 297 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRK- 355
+T + AS+P+VSY+KA+D+++ V LFVF +++EYAAVN+++ +E +F++ K
Sbjct: 311 STIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTV-EERKQFKKTGKI 369
Query: 356 ------NKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQV 409
+ +A A + Y S++D + + + ++ K +P + ++
Sbjct: 370 SRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDF-----MRRKSICSPSTDSSRIKR 424
Query: 410 MPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
+ ++ ++ IDT SR FP+ +++FN+FYW +Y
Sbjct: 425 RKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVY 466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,030,955
Number of Sequences: 37866
Number of extensions: 717279
Number of successful extensions: 2325
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2117
Number of HSP's gapped (non-prelim): 101
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.