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Search of human proteins with 110347433
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 916 0.0
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 906 0.0
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 759 0.0
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 754 0.0
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 726 0.0
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 724 0.0
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 724 0.0
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 630 0.0
gi|4504023 glycine receptor, beta [Homo sapiens] 369 e-102
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 286 2e-77
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 286 2e-77
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 284 1e-76
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 284 1e-76
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 281 1e-75
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 280 1e-75
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 280 2e-75
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 280 2e-75
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 276 2e-74
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 5e-74
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 275 5e-74
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 275 5e-74
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 275 8e-74
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 270 1e-72
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 270 2e-72
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 268 1e-71
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 916 bits (2368), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
Sbjct: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
Query: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
Sbjct: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
Query: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
Sbjct: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
Query: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
Sbjct: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
Query: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
Sbjct: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
Query: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDE 360
SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDE
Sbjct: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDE 360
Query: 361 VRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRAC 420
VRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRAC
Sbjct: 361 VRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRAC 420
Query: 421 FPLAFLIFNIFYWVIYKILRHEDIHQQQD 449
FPLAFLIFNIFYWVIYKILRHEDIHQQQD
Sbjct: 421 FPLAFLIFNIFYWVIYKILRHEDIHQQQD 449
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 906 bits (2342), Expect = 0.0
Identities = 449/464 (96%), Positives = 449/464 (96%), Gaps = 15/464 (3%)
Query: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
Sbjct: 1 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR 60
Query: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
Sbjct: 61 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP 120
Query: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
Sbjct: 121 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM 180
Query: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
Sbjct: 181 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF 240
Query: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
Sbjct: 241 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS 300
Query: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNK--- 357
SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNK
Sbjct: 301 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA 360
Query: 358 ------------DDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 405
DDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
Sbjct: 361 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV 420
Query: 406 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 449
FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
Sbjct: 421 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD 464
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 759 bits (1959), Expect = 0.0
Identities = 370/440 (84%), Positives = 402/440 (91%), Gaps = 7/440 (1%)
Query: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Query: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
Query: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
Query: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
Query: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
Query: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRK-NKDDEVRESRFSFTAYGM 373
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR+ +K+DE E RF+F+AYGM
Sbjct: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGM 369
Query: 374 GP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLI 427
GP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKID ISR FP+AFLI
Sbjct: 370 GPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLI 429
Query: 428 FNIFYWVIYKILRHEDIHQQ 447
FN+FYW+IYKI+R ED+H Q
Sbjct: 430 FNMFYWIIYKIVRREDVHNQ 449
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 754 bits (1947), Expect = 0.0
Identities = 369/448 (82%), Positives = 402/448 (89%), Gaps = 15/448 (3%)
Query: 15 YFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTC 74
Y WE + SL A+KE ++ARS PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+C
Sbjct: 10 YLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSC 69
Query: 75 NIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFA 134
NIFINSFGSIAETTMDYRVNIFLRQ+WNDPRLAY+EYPDDSLDLDPSMLDSIWKPDLFFA
Sbjct: 70 NIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFA 129
Query: 135 NEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGY 194
NEKGA+FHE+TTDNKLLRI +NGNVLYSIR+TLTL+CPMDLKNFPMDVQTCIMQLESFGY
Sbjct: 130 NEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
Query: 195 TMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMG 254
TMNDLIFEWQ++ VQVA+GLTLPQF+LKEEKDLRYCTKHYNTGKFTCIE RFHLERQMG
Sbjct: 190 TMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMG 249
Query: 255 YYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVK 314
YYLIQMYIPSLLIVILSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVK
Sbjct: 250 YYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVK 309
Query: 315 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKN---------KDDEVRESR 365
AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKR++ ++DE E R
Sbjct: 310 AIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGR 369
Query: 366 FSFTAYGMGP-CLQAKDGMTPKGPN-----HPVQVMPKSPDEMRKVFIDRAKKIDTISRA 419
F+F+AYGMGP CLQAKDG++ KG N +P KSP+EMRK+FI RAKKID ISR
Sbjct: 370 FNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRI 429
Query: 420 CFPLAFLIFNIFYWVIYKILRHEDIHQQ 447
FP+AFLIFN+FYW+IYKI+R ED+H Q
Sbjct: 430 GFPMAFLIFNMFYWIIYKIVRREDVHNQ 457
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 726 bits (1875), Expect = 0.0
Identities = 357/422 (84%), Positives = 385/422 (91%), Gaps = 4/422 (0%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRR--KRKNKDDEV-RESRFSFTAYGMGPCLQAKDGMTPK 386
ALLEYAAVNFVSRQHKE LR RR KR+NK+++V RESRF+F+ YGMG CLQ KDG K
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVK 390
Query: 387 G-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIH 445
P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW+ YKI+RHED+H
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH 450
Query: 446 QQ 447
++
Sbjct: 451 KK 452
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 724 bits (1870), Expect = 0.0
Identities = 355/422 (84%), Positives = 384/422 (90%), Gaps = 4/422 (0%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRR--KRKNKDDEV-RESRFSFTAYGMGPCLQAKDGMTPK 386
ALLEYAAVNFVSRQHKE LR RR KR+NK+++V RESRF+F+ YGMG CLQ KDG K
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVK 390
Query: 387 G-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIH 445
P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW+ YKI+RHED+H
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH 450
Query: 446 QQ 447
++
Sbjct: 451 KK 452
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 724 bits (1870), Expect = 0.0
Identities = 355/422 (84%), Positives = 384/422 (90%), Gaps = 4/422 (0%)
Query: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGS+ ETTM
Sbjct: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTM 90
Query: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
Query: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
Query: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
Query: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
Query: 330 ALLEYAAVNFVSRQHKELLRFRR--KRKNKDDEV-RESRFSFTAYGMGPCLQAKDGMTPK 386
ALLEYAAVNFVSRQHKE LR RR KR+NK+++V RESRF+F+ YGMG CLQ KDG K
Sbjct: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVK 390
Query: 387 G-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIH 445
P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW+ YKI+RHED+H
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH 450
Query: 446 QQ 447
++
Sbjct: 451 KK 452
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 630 bits (1625), Expect = 0.0
Identities = 312/397 (78%), Positives = 346/397 (87%), Gaps = 10/397 (2%)
Query: 21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 80
LL +A +E S S PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS
Sbjct: 22 LLRVALAKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINS 81
Query: 81 FGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 140
F SI +TTMDYRVN+FLRQ+WNDPRL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGAN
Sbjct: 82 FSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGAN 141
Query: 141 FHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLI 200
FHEVTTDNKLLRIFKNGNVLYSIRLTL LSC MDLKNFPMD+QTC MQLESFGYTM DL+
Sbjct: 142 FHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLV 201
Query: 201 FEWQDEAP-VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQ 259
FEW ++AP VQVAEGLTLPQF+L++EKDL CTKHYNTGKFTCIEV+FHLERQMGYYLIQ
Sbjct: 202 FEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQ 261
Query: 260 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 319
MYIPSLLIVILSWVSFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIW
Sbjct: 262 MYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 321
Query: 320 MAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKN---KDDEVRESRFSFTAYGMGPC 376
MAVCLLFVF+ALLEYAA+NFVSRQHKE +R RR+++ ++D ++ESRF F YG+G C
Sbjct: 322 MAVCLLFVFAALLEYAAINFVSRQHKEFIRLRRRQRRQRLEEDIIQESRFYFRGYGLGHC 381
Query: 377 LQAKDGMTPKG-----PNHPVQVMPKSPDEMRKVFID 408
LQA+DG +G P P ++ + + RK+++D
Sbjct: 382 LQARDGGPMEGSGIYSPQPPAPLL-REGETTRKLYVD 417
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 369 bits (946), Expect = e-102
Identities = 220/465 (47%), Positives = 285/465 (61%), Gaps = 59/465 (12%)
Query: 25 LVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSI 84
L ++++ +R S S+ L++L+ YD RIRPNFKG PV+V NIFINSFGSI
Sbjct: 38 LCPSQQSAEDLARVPANSTSNILNRLL---VSYDPRIRPNFKGIPVDVVVNIFINSFGSI 94
Query: 85 AETTMDYRVNIFLRQKWNDPRLAY-SEYP-DDSLDLDPSMLDSIWKPDLFFANEKGANFH 142
ETTMDYRVNIFLRQKWNDPRL S++ D+L +DP+M +WKPDLFFANEK ANFH
Sbjct: 95 QETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFH 154
Query: 143 EVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFE 202
+VT +N LL IF++G+VL S+RL++TLSCP+DL FPMD Q C MQLESFGYT +DL F
Sbjct: 155 DVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFI 214
Query: 203 WQDEAPVQVAEGLTLPQFLLKEEKDLRY--CTKHY-NTGKFTCIEVRFHLERQMGYYLIQ 259
WQ PVQ+ E + LPQF +K+E D+ Y CTK+Y TG +TC+EV F L RQ+G+Y++
Sbjct: 215 WQSGDPVQL-EKIALPQFDIKKE-DIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMG 272
Query: 260 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIW 319
+Y P+LLIV+LSW+SFWIN DA+ ARV LGI +VL++ ++ + A LPKVSYVKA+D+W
Sbjct: 273 VYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVW 332
Query: 320 MAVCLLFVFSALLEYAAV----NFVSRQHKELLRFRRKRKNKDDEVRESRFSFTAYGMGP 375
+ CLLF F++L+EYA V N R E R K + D + T G G
Sbjct: 333 LIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARI-AKAEQADGKGGNVAKKNTVNGTGT 391
Query: 376 -----------------CLQAKD---------GMTPKG--------PNHPVQV---MPKS 398
C D G P+ P++V + KS
Sbjct: 392 PVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKS 451
Query: 399 -------PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
P + V AK+ID +RA FP FL FN+ YW IY
Sbjct: 452 QAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIY 496
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 286 bits (733), Expect = 2e-77
Identities = 165/436 (37%), Positives = 243/436 (55%), Gaps = 51/436 (11%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T
Sbjct: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEE 225
T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 226 KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPAR 285
+ L + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 286 VALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV----- 340
VALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 341 SRQHKELLRFRRKRKNKDDEVRESR-----------------FSFTAYGMGPCLQAKDGM 383
++ K+L K KN + +R + + G+G +
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 384 TPKGPNHPVQVMPK-----------------------SPDEMRKVFIDRAKKIDTISRAC 420
G + Q MP+ S +++ + ID SR
Sbjct: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455
Query: 421 FPLAFLIFNIFYWVIY 436
FP F +FN+ YW+ Y
Sbjct: 456 FPFTFSLFNLVYWLYY 471
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 286 bits (733), Expect = 2e-77
Identities = 165/436 (37%), Positives = 243/436 (55%), Gaps = 51/436 (11%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
+DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL
Sbjct: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T
Sbjct: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEE 225
T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E
Sbjct: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216
Query: 226 KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPAR 285
+ L + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ AR
Sbjct: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275
Query: 286 VALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV----- 340
VALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335
Query: 341 SRQHKELLRFRRKRKNKDDEVRESR-----------------FSFTAYGMGPCLQAKDGM 383
++ K+L K KN + +R + + G+G +
Sbjct: 336 PQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISF 395
Query: 384 TPKGPNHPVQVMPK-----------------------SPDEMRKVFIDRAKKIDTISRAC 420
G + Q MP+ S +++ + ID SR
Sbjct: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455
Query: 421 FPLAFLIFNIFYWVIY 436
FP F +FN+ YW+ Y
Sbjct: 456 FPFTFSLFNLVYWLYY 471
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 284 bits (726), Expect = 1e-76
Identities = 171/473 (36%), Positives = 255/473 (53%), Gaps = 60/473 (12%)
Query: 14 FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73
F W L+++ V + + + S D L K GYD R+RP+F GPPV V
Sbjct: 10 FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
Query: 74 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133
NI I S ++E MDY + ++ +Q W D RL+Y+ P + L LD + D +W PD +F
Sbjct: 64 MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
Query: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193
N+K + H VT N+++R+ +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
Query: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250
YT +D+ F W+ D+ V + LPQF + D + TK ++TG + + + F L+
Sbjct: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
Query: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310
R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+
Sbjct: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
Query: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV------SRQHK----------ELLRFRRKR 354
YVKAID+++ C +FVF ALLEYA VN++ RQ K E +R +
Sbjct: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK 359
Query: 355 KNKDDEV--------RESRFSFTAYGMG-----------PCLQAKDGMTPK---GPNHPV 392
+ + + E S G+G +Q + P+ G N
Sbjct: 360 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALE 419
Query: 393 QVMPKSPDEMRK---------VFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ + + +R+ + ID SR FP+ F FNI YW+ Y
Sbjct: 420 RHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 284 bits (726), Expect = 1e-76
Identities = 154/412 (37%), Positives = 229/412 (55%), Gaps = 22/412 (5%)
Query: 46 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPR 105
+L L G +GY RP GPPVNV + + S I+E M+Y + +FL Q W D R
Sbjct: 40 WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99
Query: 106 LAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRL 165
L+Y+ + +++L LD +D +W PD F N K A FH+VT +NKL+R+ +G +LYSIR+
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158
Query: 166 TLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKE 224
T T++C MDL +PMD Q C++ LES+GY+ D+++ W + + + + L L QF +
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218
Query: 225 EKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
+ + G+F + + FHL R G Y+IQ Y+PS+L+V +SWVSFWI+ A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278
Query: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNF---VS 341
RV+LGITTVLTMTT +R+SLP+ S +KA+D++ +C +FVF+AL+EYA +F
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYR 338
Query: 342 RQHKELLRFRRKRKNKDDEVRESRFSFTAYGMGP--CLQAKDGMTPKGPNHPVQVMPKSP 399
++ K ++ R R D FS +A G+ + + P + +
Sbjct: 339 KKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVET 398
Query: 400 DEMRKVFIDR---------------AKKIDTISRACFPLAFLIFNIFYWVIY 436
E +K R A ID +RA FP AF N+ YW Y
Sbjct: 399 GETKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 281 bits (718), Expect = 1e-75
Identities = 144/330 (43%), Positives = 211/330 (63%), Gaps = 13/330 (3%)
Query: 14 FYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVT 73
F W L+++ V + + + S D L K GYD R+RP+F GPPV V
Sbjct: 10 FGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLK------GYDIRLRPDFGGPPVAVG 63
Query: 74 CNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFF 133
NI I S ++E MDY + ++ +Q W D RL+Y+ P + L LD + D +W PD +F
Sbjct: 64 MNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYF 122
Query: 134 ANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG 193
N+K + H VT N+++R+ +G VLY +R+T T +C MDL+ +P+D Q C +++ES+G
Sbjct: 123 LNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYG 182
Query: 194 YTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEEKDLRYCTKH--YNTGKFTCIEVRFHLE 250
YT +D+ F W+ D+ V + LPQF + D + TK ++TG + + + F L+
Sbjct: 183 YTTDDIEFYWRGDDNAVTGVTKIELPQFSIV---DYKLITKKVVFSTGSYPRLSLSFKLK 239
Query: 251 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 310
R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+
Sbjct: 240 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 299
Query: 311 SYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340
YVKAID+++ C +FVF ALLEYA VN++
Sbjct: 300 PYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
Score = 31.6 bits (70), Expect = 1.5
Identities = 13/24 (54%), Positives = 15/24 (62%)
Query: 413 IDTISRACFPLAFLIFNIFYWVIY 436
ID SR FP+ F FNI YW+ Y
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 280 bits (717), Expect = 1e-75
Identities = 162/450 (36%), Positives = 249/450 (55%), Gaps = 49/450 (10%)
Query: 34 ARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRV 93
A S + P + S + + GYD R+RP+F GPPV+V I + S ++E MDY +
Sbjct: 25 AHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTL 84
Query: 94 NIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRI 153
++ +Q W D RL+YS P + L LD + D +W PD +F N+K + H VT N+++R+
Sbjct: 85 TMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRL 143
Query: 154 FKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVA 212
+G VLY +R+T T +C MDL+ +P+D Q C +++ES+GYT +D+ F W E V
Sbjct: 144 HPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGV 203
Query: 213 EGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSW 272
+ LPQF + + K + + + TG + + + F L+R +GY+++Q Y+PS LI ILSW
Sbjct: 204 NKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSW 262
Query: 273 VSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALL 332
VSFWIN DA+ ARVALGITTVLTMTT S+ R +LPK+ YVKAIDI++ C +FVF ALL
Sbjct: 263 VSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALL 322
Query: 333 EYAAVNFV---SRQHKELLRFRRKRKNKDDEVRESRFSFTAYG--MGPCLQAKDGMT--- 384
EYA VN++ K+ + + N+ +++ ++ A+G + L+ ++ +
Sbjct: 323 EYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSE 382
Query: 385 -------PKGPNH---PVQVMPKSPDEMRKVF---IDR---------------------- 409
PK + + + P R+ + +DR
Sbjct: 383 VLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPD 442
Query: 410 ---AKKIDTISRACFPLAFLIFNIFYWVIY 436
ID SR FP+ F +FN+ YW+ Y
Sbjct: 443 LTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 280 bits (715), Expect = 2e-75
Identities = 166/450 (36%), Positives = 257/450 (57%), Gaps = 31/450 (6%)
Query: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
Query: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
Query: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
Query: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
Query: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
Query: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ ++K
Sbjct: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKE 356
Query: 355 KNKDDEVRESRFSFTAYGMGPCLQ--------AKDGMTPKGPNHPVQVMPKSPDEMRKVF 406
K ++ + ++ P L +K TP+ P P E +K F
Sbjct: 357 K-ASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKP----ENKPAEAKKTF 411
Query: 407 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ KID +SR FP+ F FN+ YW Y
Sbjct: 412 -NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 280 bits (715), Expect = 2e-75
Identities = 166/450 (36%), Positives = 257/450 (57%), Gaps = 31/450 (6%)
Query: 3 HVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIR 62
++ + + L+ F W+ A L+ +A + D A++ + LD+L+ GYD R+R
Sbjct: 6 NIYNMQFLLFVFLVWDPARLV--LANIQEDEAKNNITIFTR--ILDRLL---DGYDNRLR 58
Query: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSM 122
P V NI++ SFG +++T M+Y +++F RQKW D RL + P + L L+ M
Sbjct: 59 PGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKG-PMNILRLNNLM 117
Query: 123 LDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDV 182
IW PD FF N K + H +T NKLLRI +G +LY++RLT+ CPM L++FPMD
Sbjct: 118 ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDA 177
Query: 183 QTCIMQLESFGYTMNDLIFEWQDEAP--VQVA-EGLTLPQFLLKEEKDLRYCTKHYNTGK 239
+C ++ S+ YT +++ + W A VQVA +G L Q+ L + + K +TG+
Sbjct: 178 HSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS-STGE 236
Query: 240 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 299
+T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR G+TTVLTMTT
Sbjct: 237 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 296
Query: 300 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-----HKELLRFRRKR 354
S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++ K ++ ++K
Sbjct: 297 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKE 356
Query: 355 KNKDDEVRESRFSFTAYGMGPCLQ--------AKDGMTPKGPNHPVQVMPKSPDEMRKVF 406
K ++ + ++ P L +K TP+ P P E +K F
Sbjct: 357 K-ASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKP----ENKPAEAKKTF 411
Query: 407 IDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ KID +SR FP+ F FN+ YW Y
Sbjct: 412 -NSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 276 bits (707), Expect = 2e-74
Identities = 162/419 (38%), Positives = 234/419 (55%), Gaps = 37/419 (8%)
Query: 44 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWND 103
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
Query: 104 PRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSI 163
RL + P + L L+ M+ IW PD FF N K + H +TT NKL RI +NG +LY++
Sbjct: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
Query: 164 RLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLK 223
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W+ + P+ E LL+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWK-KGPLYSVEVPEESSSLLQ 207
Query: 224 EE---KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 280
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Query: 281 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 340
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVFSAL+E+AAVN+
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
Query: 341 SRQHKELLRFRRKRK-----------NKDDEVRESRF------------SFTAYGMGPCL 377
+ + + KRK +K E E+ T+ + P +
Sbjct: 328 TNLQTQ----KAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSL-PIV 382
Query: 378 QAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ + +Q P +P + F KID SR FP+AF FN+ YWV+Y
Sbjct: 383 SSSEANKVLTRAPILQSTPVTPPPLSPAF-GGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (704), Expect = 5e-74
Identities = 161/404 (39%), Positives = 239/404 (59%), Gaps = 21/404 (5%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ P L L+ M IW PD FF N K + H +T NKLLRI ++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAP--VQVAE-GLTLPQF-LL 222
+ CPM L++FPMD C ++ S+ YT ++++EW E V VAE G L Q+ LL
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+ D +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 343 Q----HKELLRFRRKRKNKDDEVRESR-FSFTAYGMGPCLQAKD----GMTPKGPNHPVQ 393
+ + + + +K KD ++++ ++ TA P L D + P +
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 394 VMPKS-PDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V P++ P E +K F + KID +SR FPL F IFN+ YW Y
Sbjct: 400 VKPETKPPEPKKTF-NSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 275 bits (704), Expect = 5e-74
Identities = 152/405 (37%), Positives = 227/405 (56%), Gaps = 34/405 (8%)
Query: 54 TSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD 113
T+GY+ +RPNF G PV + + I S SI+E+ MDY I+LRQ+W D RL + +
Sbjct: 45 TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102
Query: 114 DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPM 173
S LD +++ +W PD + K + HEVT N+L+R+F NG VLY++R+T T++C M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162
Query: 174 DLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QDEAPVQVAEGLTLPQFLLKEEKDLRYCT 232
DL +PMD QTC +QLES+GY ND+ F W + V+ E L L Q+ ++ RY T
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIE-----RYFT 217
Query: 233 ----KHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVAL 288
TG +T + ++F L R + Y++++ Y+PS +V+LSWVSFWI++D+ PAR +
Sbjct: 218 LVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCI 277
Query: 289 GITTVLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKEL 347
G+TTVL+MTT GSR SLP + ++KAID+++ +C FVF ALLEYA ++ S Q
Sbjct: 278 GVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQ---- 333
Query: 348 LRFRRKRKNKDDEVRE---------------SRFSFTAYGMGPCLQAKDGMTPKGPNHPV 392
+ K + EV E + SF + + +T K +
Sbjct: 334 -QMAAKDRGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFK 392
Query: 393 QVMPKSPDEMRKVF-IDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
V + + F I +D S+ FPL F++ N+FYW Y
Sbjct: 393 FVFREKMGRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 275 bits (702), Expect = 8e-74
Identities = 150/400 (37%), Positives = 233/400 (58%), Gaps = 17/400 (4%)
Query: 50 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS 109
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
Query: 110 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTL 169
P L L+ + IW PD FF N K + H +TT NKLLR+ +G +LY++RLT++
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
Query: 170 SCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD---EAPVQVAEGLTLPQFLLKEEK 226
CPM L++FPMD C ++ S+ Y +++++ W + ++ V +G L Q+ L +
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 227 DLRYCTKHYNT--GKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 284
T++ +T G++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PA
Sbjct: 232 ---VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
Query: 285 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ- 343
R G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ +++
Sbjct: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
Query: 344 ----HKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSP 399
K+ L + +K ++ + +S +FT M TP G ++ V K
Sbjct: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPS 408
Query: 400 DEM---RKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+E K + KID +SR FP+ F FN+ YW Y
Sbjct: 409 EEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 270 bits (691), Expect = 1e-72
Identities = 159/416 (38%), Positives = 235/416 (56%), Gaps = 34/416 (8%)
Query: 47 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 106
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 107 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 166
+ + P L L+ + IW PD FF N K + H +TT NKLLR+ NG +LY++RLT
Sbjct: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 167 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ--DEAPVQVAE-GLTLPQF-LL 222
+ CPM L++FPMDV C ++ S+ YT ++++ W V+VA+ G L Q+ LL
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 223 KEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 282
+TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 247 GHVVGTEIIRS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 304
Query: 283 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR 342
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVFSAL+E+A VN+ ++
Sbjct: 305 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 364
Query: 343 Q------HKELLRFRRKRKNKDDEVRESRFSFTAYGMG-PCLQAKD--------GMTPKG 387
+ K K+K +++ +F G P AKD G P
Sbjct: 365 RSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSA 424
Query: 388 PNHP-VQVMPK------SPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ P + PK SP E + + K+D ISR FP+ F IFN+ YW Y
Sbjct: 425 SSTPTIIASPKATYVQDSPTETKT--YNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 270 bits (690), Expect = 2e-72
Identities = 149/407 (36%), Positives = 234/407 (57%), Gaps = 25/407 (6%)
Query: 53 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP 112
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
Query: 113 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCP 172
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+F +G+VLYS+R+T+T C
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
Query: 173 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEEKDLRYC 231
MD +FP+D QTC ++LES+ YT DL+ W++ + ++ E ++L QFL+++
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
Query: 232 TKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 291
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
Query: 292 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS----RQHKEL 347
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ R+ ++L
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
Query: 348 LR--------FRRKRKNKDDEVRESRF-SFTAYGMGPCLQAKD---------GMTPKGPN 389
K D ES S Y L ++ G++ +
Sbjct: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
Query: 390 HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
+ + K R ID SR FP +++ FN+ YW ++
Sbjct: 445 ARKKGLLKGQTGFR--IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 268 bits (684), Expect = 1e-71
Identities = 150/418 (35%), Positives = 239/418 (57%), Gaps = 18/418 (4%)
Query: 35 RSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 94
RS SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
Query: 95 IFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIF 154
++LR W D RL++ + S+ D ++ IW PD+FF + K + H+ TTDN +LR+
Sbjct: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
Query: 155 KNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW-QDEAPVQVAE 213
+G VLYS+R+T+T C MD FP+D QTC +++ES+ YT +DL+ W + ++ E
Sbjct: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
Query: 214 GLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV 273
++L QFL++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
Query: 274 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE 333
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
Query: 334 YAAVNFVSRQHKELLRFRRKRKNKDDEVRESRFSFT--AYGMGPCLQAKDGMTPKGPNHP 391
YAAVN+++ + + R++ + R + Y G + D P+ P
Sbjct: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGE-VNDLDNYMPENGEKP 420
Query: 392 VQVMPK--------SPD--EMRKVFIDR---AKKIDTISRACFPLAFLIFNIFYWVIY 436
++M + SP R ++ ID SR FP A+++FN+ YW I+
Sbjct: 421 DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIF 478
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,665,841
Number of Sequences: 37866
Number of extensions: 705088
Number of successful extensions: 2320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2111
Number of HSP's gapped (non-prelim): 101
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.