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Search of human proteins with 110347416
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 960 0.0
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 659 0.0
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 656 0.0
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 637 0.0
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 637 0.0
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 409 e-114
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 371 e-103
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 355 6e-98
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 351 9e-97
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 349 3e-96
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 346 2e-95
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 346 2e-95
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 340 2e-93
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 340 2e-93
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 280 2e-75
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 271 9e-73
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 271 1e-72
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 271 1e-72
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 268 8e-72
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 263 3e-70
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 258 8e-69
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 258 8e-69
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 258 1e-68
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 255 5e-68
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 254 9e-68
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 960 bits (2481), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDK 60
MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDK
Sbjct: 1 MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDK 60
Query: 61 KLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNS 120
KLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNS
Sbjct: 61 KLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNS 120
Query: 121 NMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM 180
NMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM
Sbjct: 121 NMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM 180
Query: 181 DEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDY 240
DEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDY
Sbjct: 181 DEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDY 240
Query: 241 VVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLS 300
VVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLS
Sbjct: 241 VVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLS 300
Query: 301 TIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDS 360
TIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDS
Sbjct: 301 TIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDS 360
Query: 361 SRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCC 420
SRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCC
Sbjct: 361 SRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCC 420
Query: 421 YEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
YEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL
Sbjct: 421 YEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 659 bits (1700), Expect = 0.0
Identities = 316/466 (67%), Positives = 384/466 (82%), Gaps = 20/466 (4%)
Query: 5 LLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRP 64
+LLLL L+ G ++ +D+YED +SN+ WVL PK + DVT+ILN LL YD KLRP
Sbjct: 27 ILLLLSLYPGFTSQK---SDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRP 83
Query: 65 DIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVG 124
DIG+KPT+I D+YVNSIGPV++INMEY IDIFFAQTW D RL+FNST+K+L LNSNMVG
Sbjct: 84 DIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVG 143
Query: 125 LIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHS 184
IWIPDT FRNSK A+AHWITTPN++LRIWNDG++LYTLRLTI+AECQLQLHNFPMDEHS
Sbjct: 144 KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHS 203
Query: 185 CPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
CPL FSSYGYP+EE++Y+W+++SVE D +SWRLYQF F+GLRNTTE+V T++GDYVVM+
Sbjct: 204 CPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMS 263
Query: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
+YF+LSRRMGYFTIQTYIPC L VVLSWVSFWI KDA PART+LGITTVLTMTTLSTIAR
Sbjct: 264 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIAR 323
Query: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPT---TTKKTTSLLHPDSS 361
KSLP+VSYVTAMDLFV+VCF+FVF+AL+EY TL+Y+ S RKP+ KK LL
Sbjct: 324 KSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLL----- 378
Query: 362 RWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCY 421
S +AP+ +D+R P +A I +NN+ + QE ++ YECLDGKDC SFFCC+
Sbjct: 379 ----RMFSFKAPT----IDIR-PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCF 429
Query: 422 EECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
E+C++G+WR GRIHI I ++DSY+R+FFPT+F LFNLVYWV YLYL
Sbjct: 430 EDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 475
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 656 bits (1692), Expect = 0.0
Identities = 314/463 (67%), Positives = 382/463 (82%), Gaps = 22/463 (4%)
Query: 5 LLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRP 64
+LLLL L+ G ++ +D+YED +SN+ WVL PK + DVT+ILN LL YD KLRP
Sbjct: 27 ILLLLSLYPGFTSQK---SDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRP 83
Query: 65 DIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVG 124
DIG+KPT+I D+YVNSIGPV++INMEY IDIFFAQTW D RL+FNST+K+L LNSNMVG
Sbjct: 84 DIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVG 143
Query: 125 LIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHS 184
IWIPDT FRNSK A+AHWITTPN++LRIWNDG++LYTLRLTI+AECQLQLHNFPMDEHS
Sbjct: 144 KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHS 203
Query: 185 CPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
CPL FSSYGYP+EE++Y+W+++SVE D +SWRLYQF F+GLRNTTE+V T++GDYVVM+
Sbjct: 204 CPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMS 263
Query: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
+YF+LSRRMGYFTIQTYIPC L VVLSWVSFWI KDA PART+LGITTVLTMTTLSTIAR
Sbjct: 264 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIAR 323
Query: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 364
KSLP+VSYVTAMDLFV+VCF+FVF+AL+EY TL+Y+ S RKP+ K D +
Sbjct: 324 KSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK--------DKKKKN 375
Query: 365 PERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEEC 424
P AP+ +D+R P +A I +NN+ + QE ++ YECLDGKDC SFFCC+E+C
Sbjct: 376 P------APT----IDIR-PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDC 424
Query: 425 KSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
++G+WR GRIHI I ++DSY+R+FFPT+F LFNLVYWV YLYL
Sbjct: 425 RTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 637 bits (1644), Expect = 0.0
Identities = 315/506 (62%), Positives = 384/506 (75%), Gaps = 60/506 (11%)
Query: 5 LLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRP 64
+LLLL L+ G ++ +D+YED +SN+ WVL PK + DVT+ILN LL YD KLRP
Sbjct: 27 ILLLLSLYPGFTSQK---SDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRP 83
Query: 65 DIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVG 124
DIG+KPT+I D+YVNSIGPV++INMEY IDIFFAQTW D RL+FNST+K+L LNSNMVG
Sbjct: 84 DIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVG 143
Query: 125 LIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHS 184
IWIPDT FRNSK A+AHWITTPN++LRIWNDG++LYTLRLTI+AECQLQLHNFPMDEHS
Sbjct: 144 KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHS 203
Query: 185 CPLIFSSY----------------------------------------GYPKEEMIYRWR 204
CPL FSS+ GYP+EE++Y+W+
Sbjct: 204 CPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPPTLASRVAGISDGYPREEIVYQWK 263
Query: 205 KNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPC 264
++SVE D +SWRLYQF F+GLRNTTE+V T++GDYVVM++YF+LSRRMGYFTIQTYIPC
Sbjct: 264 RSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPC 323
Query: 265 ILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCF 324
L VVLSWVSFWI KDA PART+LGITTVLTMTTLSTIARKSLP+VSYVTAMDLFV+VCF
Sbjct: 324 TLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCF 383
Query: 325 LFVFAALMEYATLNYYSSCRKPT---TTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDM 381
+FVF+AL+EY TL+Y+ S RKP+ KK LL S +AP+ +D+
Sbjct: 384 IFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLL---------RMFSFKAPT----IDI 430
Query: 382 RPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILEL 441
R P +A I +NN+ + QE ++ YECLDGKDC SFFCC+E+C++G+WR GRIHI I ++
Sbjct: 431 R-PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKM 489
Query: 442 DSYSRVFFPTSFLLFNLVYWVGYLYL 467
DSY+R+FFPT+F LFNLVYWV YLYL
Sbjct: 490 DSYARIFFPTAFCLFNLVYWVSYLYL 515
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 637 bits (1644), Expect = 0.0
Identities = 307/447 (68%), Positives = 361/447 (80%), Gaps = 19/447 (4%)
Query: 21 KVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVN 80
K ++++ ED + N+ WVLAPK + D+T ILN LL+ YD KLRPDIG++PTVI+ D+YVN
Sbjct: 38 KADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVN 97
Query: 81 SIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAE 140
SIGPV INMEY IDI FAQTW DSRL+FNSTMK+L LNSNMVG IWIPDT FRNS+ ++
Sbjct: 98 SIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSD 157
Query: 141 AHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMI 200
AHWITTPN+LLRIWNDG++LYTLRLTINAEC LQLHNFPMDEHSCPL FSSYGYPK E+
Sbjct: 158 AHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIE 217
Query: 201 YRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQT 260
Y+W+K SVE AD K WRLYQF F+GLRN+TEI T +GDYV+MTI+F+LSRRMGYFTIQT
Sbjct: 218 YKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQT 277
Query: 261 YIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFV 320
YIPCILTVVLSWVSFWI KDA PART+LGITTVLTMTTLSTIARKSLP+VSYVTAMDLFV
Sbjct: 278 YIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFV 337
Query: 321 TVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLD 380
+VCF+FVFAALMEY TL+Y++S +K T K L + S+
Sbjct: 338 SVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKL-----------------KNKASMTP 380
Query: 381 MRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILE 440
P + +I +NN Q ED Y+CL+GKDC SFFCC+E+C++GSWR+GRIHI I +
Sbjct: 381 GLHPGSTLIPMNNISVPQ--EDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAK 438
Query: 441 LDSYSRVFFPTSFLLFNLVYWVGYLYL 467
+DSYSR+FFPT+F LFNLVYWVGYLYL
Sbjct: 439 IDSYSRIFFPTAFALFNLVYWVGYLYL 465
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 409 bits (1051), Expect = e-114
Identities = 202/441 (45%), Positives = 276/441 (62%), Gaps = 23/441 (5%)
Query: 46 DVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDS 105
+ + ILN +L YD KLRP IG KPTV+ V+I VNS+GP+S ++MEY IDI F+QTW D
Sbjct: 70 EASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDE 129
Query: 106 RLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRL 165
RL +N T + L LN N+V +WIPDT FRNSK H IT PNQ++RI+ DGK+LYT+R+
Sbjct: 130 RLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRM 189
Query: 166 TINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMG 225
TI+A C L + FPMD HSCPL FSS+ YP+ EMIY+W +E ++ SW+L+QFDF G
Sbjct: 190 TIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTG 249
Query: 226 LRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPAR 285
+ N TEI+TT GD++VMTI+F +SRR GY Q Y+P +T +LSWVSFWIK ++ PAR
Sbjct: 250 VSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPAR 309
Query: 286 TALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRK 345
T+LGIT+VLTMTTL T +RK+ PRVSY+TA+D ++ +CF+F F AL+E+A LN+
Sbjct: 310 TSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL--IYN 367
Query: 346 PTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCV 405
T + L HP + R +A S + I +E
Sbjct: 368 QTKAHASPKLRHPRINSRAHAR--TRARSRACARQHQEAFVCQIVTTEGSDGEERPSCSA 425
Query: 406 YE-------------------CLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSR 446
+ C K + +FC +C+ +W++GR+ I + LD+YSR
Sbjct: 426 QQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSR 485
Query: 447 VFFPTSFLLFNLVYWVGYLYL 467
V FP +F FN++YW+ L L
Sbjct: 486 VVFPVTFFFFNVLYWLVCLNL 506
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 371 bits (953), Expect = e-103
Identities = 207/447 (46%), Positives = 267/447 (59%), Gaps = 63/447 (14%)
Query: 46 DVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDS 105
+V+ IL+ LL YD +LRP G T + DIYV S GPVS + MEY +D+FF QTWTD
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 106 RLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRL 165
RL+F +IL+LN+ MV IW PDT FRN K + AH +TTPN+L RI +G ILYT+RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 166 TINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKN---SVEAADQKSWRLYQFD 222
TINA+C ++L NFPMD H+CPL F SY YPK E+IY W+K SVE ++ S L Q+D
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
Query: 223 FMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDAT 282
+G ++E + ++ G+YV+MT+YF L R+MGYF IQ Y PCI+TV+LS VSFWI K++
Sbjct: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
Query: 283 PARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSS 342
PART GITTVLTMTTLS AR SLP+VSY TAMD F+ VCF FVF+AL+E+A +NY+++
Sbjct: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTN 329
Query: 343 CR------------KPTTT-KKTTS------LLHPDSSRWIPERI-SLQAP----SNYSL 378
+ PT T K T +LHPDS + +RI SL P S +
Sbjct: 330 LQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANK 389
Query: 379 LDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDI 438
+ R P + F T
Sbjct: 390 VLTRAPILQSTPVTPPPLSPAFGGTS---------------------------------- 415
Query: 439 LELDSYSRVFFPTSFLLFNLVYWVGYL 465
++D YSR+ FP +F FNLVYWV YL
Sbjct: 416 -KIDQYSRILFPVAFAGFNLVYWVVYL 441
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 355 bits (910), Expect = 6e-98
Identities = 189/425 (44%), Positives = 261/425 (61%), Gaps = 14/425 (3%)
Query: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
T T IL++LL YD +LRP +G T + DIYV S GPVS +MEY ID+FF QTW D
Sbjct: 65 TIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHD 124
Query: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
RL+F+ MKIL LN+ + IW PDT F N K + AH +TTPN+LLR+ ++G +LYT+R
Sbjct: 125 ERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMR 184
Query: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRW---RKNSVEAADQKSWRLYQF 221
LTI+AEC + L +FPMD H+CPL F SY Y E++Y W + SVE A S RL Q+
Sbjct: 185 LTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQY 243
Query: 222 DFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDA 281
D +G TEI+ +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+ +++
Sbjct: 244 DLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRES 303
Query: 282 TPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS 341
PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+NY++
Sbjct: 304 VPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT 363
Query: 342 SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFE 401
KK L + + P + + + ++++ P I L EF
Sbjct: 364 KRSWAWEGKKVPEAL--EMKKKTPAAPAKKTSTTFNIVGTTYP----INLAKDT---EFS 414
Query: 402 DTCVYECLDGKDCQSFFCCYEEC-KSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVY 460
+ + S + + + + ++D SR+ FP F +FNLVY
Sbjct: 415 TISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVY 474
Query: 461 WVGYL 465
W Y+
Sbjct: 475 WATYV 479
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 351 bits (900), Expect = 9e-97
Identities = 172/328 (52%), Positives = 228/328 (69%), Gaps = 5/328 (1%)
Query: 28 EDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSS 87
E NQK K + T IL+ LL YD +LRP G T + DIYV S GPVS
Sbjct: 32 ESPGQNQK---EEKLCTENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSD 88
Query: 88 INMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTP 147
+ MEY +D+FF QTW D RL+++ ++IL LN+ MV +W PDT FRN K + +H +T P
Sbjct: 89 VEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAP 148
Query: 148 NQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNS 207
N+L RI +G ILYT+RLTI+AEC ++L +FPMD H+CPL F SY YPK EMIY W K
Sbjct: 149 NKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGP 208
Query: 208 VEAAD--QKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCI 265
++ + ++S L Q+D +G ++E + + G+Y+VMT+YF L R+MGYF IQTYIPCI
Sbjct: 209 EKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCI 268
Query: 266 LTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFL 325
+TV+LS VSFWI K++ PART GITTVLTMTTLS AR SLP+VSY TAMD F+ VCF
Sbjct: 269 MTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFA 328
Query: 326 FVFAALMEYATLNYYSSCRKPTTTKKTT 353
FVF+AL+E+A +NY+++ + +KT+
Sbjct: 329 FVFSALIEFAAVNYFTNIQMEKAKRKTS 356
Score = 38.5 bits (88), Expect = 0.013
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 440 ELDSYSRVFFPTSFLLFNLVYWVGYL 465
++D Y+R+ FP +F FN+VYWV YL
Sbjct: 517 KIDKYARILFPVTFGAFNMVYWVVYL 542
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 349 bits (895), Expect = 3e-96
Identities = 192/423 (45%), Positives = 255/423 (60%), Gaps = 22/423 (5%)
Query: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
T T IL+ LL YD +LRP +G + T + DIYV S GPVS MEY ID+FF Q+W D
Sbjct: 47 TIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKD 106
Query: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
RLRF M+ L LN+ + IW PDT F N K + AH +TTPN+LLR+ +DG +LYT+R
Sbjct: 107 ERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMR 166
Query: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEA--ADQKSWRLYQFD 222
LTI+AEC +QL +FPMD H+CPL F SY YP E++Y W S ++ + RL Q+
Sbjct: 167 LTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYH 226
Query: 223 FMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDAT 282
MG TE ++TS G+Y +MT +F L R++GYF IQTY+PCI+TV+LS VSFW+ +++
Sbjct: 227 LMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 286
Query: 283 PARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSS 342
PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+NY++
Sbjct: 287 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 346
Query: 343 CRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFED 402
KK R E I ++ + ++ M PP N Q
Sbjct: 347 RGWAWDGKKALEAAKIKKKR---EVILNKSTNAFTTGKMSHPP-------NIPKEQTPAG 396
Query: 403 TCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWV 462
T + K EE S S + + I ++D SR+ FP F FNLVYW
Sbjct: 397 TSNTTSVSVKPS-------EEKTSES---KKTYNSISKIDKMSRIVFPVLFGTFNLVYWA 446
Query: 463 GYL 465
YL
Sbjct: 447 TYL 449
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 346 bits (888), Expect = 2e-95
Identities = 191/436 (43%), Positives = 258/436 (59%), Gaps = 39/436 (8%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K T T IL++LL YD +LRP +G + T + DI+V S GPVS +MEY ID+FF Q
Sbjct: 36 KDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
+W D RL+F M +L LN+ M IW PDT F N K + AH +T PN+LLRI DG +L
Sbjct: 96 SWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRK---NSVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD H+CPL F SY Y + E++Y W + SV A+ S R
Sbjct: 156 YTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G + IV +S G+YVVMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYS--------SCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI 389
NY++ P KK L ++ + P A S L P A I
Sbjct: 335 NYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAP-----TATSYTPNLARGDPGLATI 389
Query: 390 TLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFF 449
+ ++ +E + E K +K + ++D SR+ F
Sbjct: 390 AKSATIEPKEVK--------------------PETKPPEPKK--TFNSVSKIDRLSRIAF 427
Query: 450 PTSFLLFNLVYWVGYL 465
P F +FNLVYW YL
Sbjct: 428 PLLFGIFNLVYWATYL 443
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 340 bits (872), Expect = 2e-93
Identities = 188/429 (43%), Positives = 252/429 (58%), Gaps = 27/429 (6%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K+ T T IL++LL YD +LRP +G T + +IYV S GPVS +MEY ID+FF Q
Sbjct: 36 KNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
W D RL+F M IL LN+ M IW PDT F N K + AH +T PN+LLRI +DG +L
Sbjct: 96 KWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKN---SVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD HSCPL F SY Y E+ Y W N SV+ A S R
Sbjct: 156 YTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G E + +S G+Y VMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYSSCRKPTTTKKTTSLLHPD-SSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVY 396
NY++ K + + +S I A +NY+ + P + T++ S
Sbjct: 335 NYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDP--VLSTISKSAT 392
Query: 397 WQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLF 456
E + + K + + ++D SR+ FP F F
Sbjct: 393 TPEPNKKPENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTF 432
Query: 457 NLVYWVGYL 465
NLVYW YL
Sbjct: 433 NLVYWATYL 441
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 340 bits (872), Expect = 2e-93
Identities = 188/429 (43%), Positives = 252/429 (58%), Gaps = 27/429 (6%)
Query: 41 KSQDTDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ 100
K+ T T IL++LL YD +LRP +G T + +IYV S GPVS +MEY ID+FF Q
Sbjct: 36 KNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQ 95
Query: 101 TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL 160
W D RL+F M IL LN+ M IW PDT F N K + AH +T PN+LLRI +DG +L
Sbjct: 96 KWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLL 155
Query: 161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKN---SVEAADQKSWR 217
YT+RLT+ AEC + L +FPMD HSCPL F SY Y E+ Y W N SV+ A S R
Sbjct: 156 YTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-R 214
Query: 218 LYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWI 277
L Q+D +G E + +S G+Y VMT +F L R++GYF IQTY+PCI+TV+LS VSFW+
Sbjct: 215 LNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWL 274
Query: 278 KKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
+++ PART G+TTVLTMTTLS AR SLP+V+Y TAMD F+ VC+ FVF+AL+E+AT+
Sbjct: 275 NRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATV 334
Query: 338 NYYSSCRKPTTTKKTTSLLHPD-SSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVY 396
NY++ K + + +S I A +NY+ + P + T++ S
Sbjct: 335 NYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDP--VLSTISKSAT 392
Query: 397 WQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLF 456
E + + K + + ++D SR+ FP F F
Sbjct: 393 TPEPNKKPENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTF 432
Query: 457 NLVYWVGYL 465
NLVYW YL
Sbjct: 433 NLVYWATYL 441
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 280 bits (716), Expect = 2e-75
Identities = 151/437 (34%), Positives = 243/437 (55%), Gaps = 25/437 (5%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
+++LL+ YD +LRPD G P + ++I + SI VS +NM+Y + ++F Q W D RL +N
Sbjct: 40 VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
LTL++ + +W+PDT F N K + H +T N+++R+ DG +LY LR+T A
Sbjct: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +P+DE +C L SYGY +++ + WR + L QF + + T
Sbjct: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
Query: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290
+ V S G Y +++ F+L R +GYF +QTY+P IL +LSWVSFWI DA+ AR ALGI
Sbjct: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
Query: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK 350
TTVLTMTT++T R++LP++ YV A+D+++ CF+FVF AL+EYA +NY R P K
Sbjct: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
Query: 351 K--------TTSLLHPDSSRWIPE--------RISLQAPSNYSLLDMRPPPTAMITLNNS 394
K + D ++ P I + ++ +++ + P + M+ + S
Sbjct: 340 KAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDAS 399
Query: 395 VYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHI------DILELDSYSRVF 448
++ + G++ ++ + R ++ I D+ +D +SR+F
Sbjct: 400 SI--QYRKAGLPRHSFGRNALERHVAQKKSRLRR-RASQLKITIPDLTDVNAIDRWSRIF 456
Query: 449 FPTSFLLFNLVYWVGYL 465
FP F FN+VYW+ Y+
Sbjct: 457 FPVVFSFFNIVYWLYYV 473
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 271 bits (693), Expect = 9e-73
Identities = 150/438 (34%), Positives = 237/438 (54%), Gaps = 26/438 (5%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
+++LL+ YD +LRPD G P + + I V SI VS +NM+Y + ++F Q+W D RL ++
Sbjct: 41 VDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYS 100
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
LTL++ + +W+PDT F N K + H +T N+++R+ DG +LY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +P+DE +C L SYGY +++ + W L QF + + +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVS 220
Query: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290
+ V + G Y +++ F L R +GYF +QTY+P L +LSWVSFWI DA+ AR ALGI
Sbjct: 221 KKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGI 280
Query: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYY---SSCRKPT 347
TTVLTMTT+ST R++LP++ YV A+D+++ CF+FVF AL+EYA +NY +K
Sbjct: 281 TTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKG 340
Query: 348 TTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNN------SVYWQEFE 401
+K+ S + ++ S L++R + L + ++Y +
Sbjct: 341 ASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSA 400
Query: 402 DTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIH-------------IDILELDSYSRVF 448
+ L ++ + G KGRI D+ +D +SR+F
Sbjct: 401 SIQYRKPLSSREAYG----RALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMF 456
Query: 449 FPTSFLLFNLVYWVGYLY 466
FP +F LFN+VYW+ Y++
Sbjct: 457 FPITFSLFNVVYWLYYVH 474
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 271 bits (692), Expect = 1e-72
Identities = 153/432 (35%), Positives = 237/432 (54%), Gaps = 17/432 (3%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
++KLL+ YD +LRPD G P + ++I + SI VS +NM+Y + ++F Q W D RL ++
Sbjct: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
LTL++ + +W+PDT F N K + H +T N+++R+ DG +LY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +P+DE +C L SYGY +++ + WR + L QF + R +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220
Query: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290
V + G Y +++ F L R +GYF +QTY+P IL +LSWVSFWI DA+ AR ALGI
Sbjct: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280
Query: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK 350
TTVLTMTT++T R++LP++ YV A+D+++ CF+FVF AL+EYA +NY R P K
Sbjct: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340
Query: 351 K---TTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI-----TLNNSVYWQEFED 402
K T+ D S+ R+ + L++ + T N+++ +
Sbjct: 341 KLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI 400
Query: 403 TCVYECLDGKDCQSFF---CCYEECKSGSWRKGRIHIDILEL------DSYSRVFFPTSF 453
+ + + F + R ++ I I +L D +SR+ FP +F
Sbjct: 401 QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTF 460
Query: 454 LLFNLVYWVGYL 465
LFNLVYW+ Y+
Sbjct: 461 SLFNLVYWLYYV 472
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 271 bits (692), Expect = 1e-72
Identities = 153/432 (35%), Positives = 237/432 (54%), Gaps = 17/432 (3%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
++KLL+ YD +LRPD G P + ++I + SI VS +NM+Y + ++F Q W D RL ++
Sbjct: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
LTL++ + +W+PDT F N K + H +T N+++R+ DG +LY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +P+DE +C L SYGY +++ + WR + L QF + R +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220
Query: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290
V + G Y +++ F L R +GYF +QTY+P IL +LSWVSFWI DA+ AR ALGI
Sbjct: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280
Query: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK 350
TTVLTMTT++T R++LP++ YV A+D+++ CF+FVF AL+EYA +NY R P K
Sbjct: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340
Query: 351 K---TTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMI-----TLNNSVYWQEFED 402
K T+ D S+ R+ + L++ + T N+++ +
Sbjct: 341 KLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGI 400
Query: 403 TCVYECLDGKDCQSFF---CCYEECKSGSWRKGRIHIDILEL------DSYSRVFFPTSF 453
+ + + F + R ++ I I +L D +SR+ FP +F
Sbjct: 401 QYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTF 460
Query: 454 LLFNLVYWVGYL 465
LFNLVYW+ Y+
Sbjct: 461 SLFNLVYWLYYV 472
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 268 bits (685), Expect = 8e-72
Identities = 128/301 (42%), Positives = 190/301 (63%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
+++LL+ YD +LRPD G P + ++I + SI VS +NM+Y + ++F Q W D RL +N
Sbjct: 40 VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
LTL++ + +W+PDT F N K + H +T N+++R+ DG +LY LR+T A
Sbjct: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +P+DE +C L SYGY +++ + WR + L QF + + T
Sbjct: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
Query: 231 EIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGI 290
+ V S G Y +++ F+L R +GYF +QTY+P IL +LSWVSFWI DA+ AR ALGI
Sbjct: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
Query: 291 TTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK 350
TTVLTMTT++T R++LP++ YV A+D+++ CF+FVF AL+EYA +NY R P K
Sbjct: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
Query: 351 K 351
K
Sbjct: 340 K 340
Score = 38.9 bits (89), Expect = 0.010
Identities = 14/29 (48%), Positives = 21/29 (72%)
Query: 437 DILELDSYSRVFFPTSFLLFNLVYWVGYL 465
D+ +D +SR+FFP F FN+VYW+ Y+
Sbjct: 483 DVNAIDRWSRIFFPVVFSFFNIVYWLYYV 511
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 263 bits (671), Expect = 3e-70
Identities = 154/427 (36%), Positives = 228/427 (53%), Gaps = 33/427 (7%)
Query: 51 LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
L+ L+ Y + RP IG P + + + V SI +S NMEY + +F Q+W DSRL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 111 STMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAE 170
T + L L+S V +W+PDT N+K+A H +T N+L+R+ DG ILY++R+T
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 171 CQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTT 230
C + L +PMDE C L SYGY E+++Y W ++ +L QF R TT
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTT 223
Query: 231 EIVT-TSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALG 289
E++ SAG + ++++F L R G + IQ+Y+P +L V +SWVSFWI + A PAR +LG
Sbjct: 224 ELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLG 283
Query: 290 ITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTT 349
ITTVLTMTTL AR SLPR S + A+D++ +C++FVFAAL+EYA ++ + RK
Sbjct: 284 ITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKA 343
Query: 350 KKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECL 409
K S + +D+R + +L+ + QE + +
Sbjct: 344 KVKVSRPRAE-------------------MDVR-NAIVLFSLSAAGVTQELAISRRQRRV 383
Query: 410 DGKDCQSFFCCYEEC----KSGSWRKG-------RIH-IDILELDSYSRVFFPTSFLLFN 457
G S+ E K G+ R G R+ ID +D Y+R FP +F N
Sbjct: 384 PGNLMGSYRSVGVETGETKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVN 443
Query: 458 LVYWVGY 464
++YW Y
Sbjct: 444 VIYWAAY 450
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 258 bits (659), Expect = 8e-69
Identities = 161/436 (36%), Positives = 234/436 (53%), Gaps = 46/436 (10%)
Query: 42 SQDTDVTLILNKLLRE---YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFF 98
SQ + L+KL+ YD ++RP+ P + +I++NS G V+ M+Y+++IF
Sbjct: 39 SQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFL 98
Query: 99 AQTWTDSRLRFNSTMK-ILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDG 157
Q W DSRL ++ L L+ +M+ IW PD F N K A H +TT N+LLRI +G
Sbjct: 99 RQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNG 158
Query: 158 KILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNS-VEAADQKSW 216
K+LY++RLT+ C + L NFPMD +C + S+GY ++I+ W + V+ A+ +
Sbjct: 159 KVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLT- 217
Query: 217 RLYQF---DFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWV 273
L QF + L T+ T G + + + F L R+MGY+ IQ YIP +L V+LSWV
Sbjct: 218 -LPQFILKEEKELGYCTKHYNT--GKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 274 SFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALME 333
SFWI DA PAR ALGITTVLTMTT S+ +R SLP+VSYV A+D+++ VC LFVFAAL+E
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 334 YATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNN 393
YA +N+ S K+ L + E ++ ++ N+S M
Sbjct: 335 YAAVNFVS-----RQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG----------- 378
Query: 394 SVYWQEFEDTCVYECLDGKDCQSFFC-----CYEECKSGSWRKGRIHIDILELDSYSRVF 448
CL KD + + K G K + +D+ SR
Sbjct: 379 -------------HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAA 425
Query: 449 FPTSFLLFNLVYWVGY 464
FP +FL+FN+ YW+ Y
Sbjct: 426 FPLAFLIFNIFYWITY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 258 bits (659), Expect = 8e-69
Identities = 161/436 (36%), Positives = 234/436 (53%), Gaps = 46/436 (10%)
Query: 42 SQDTDVTLILNKLLRE---YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFF 98
SQ + L+KL+ YD ++RP+ P + +I++NS G V+ M+Y+++IF
Sbjct: 39 SQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFL 98
Query: 99 AQTWTDSRLRFNSTMK-ILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDG 157
Q W DSRL ++ L L+ +M+ IW PD F N K A H +TT N+LLRI +G
Sbjct: 99 RQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNG 158
Query: 158 KILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNS-VEAADQKSW 216
K+LY++RLT+ C + L NFPMD +C + S+GY ++I+ W + V+ A+ +
Sbjct: 159 KVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLT- 217
Query: 217 RLYQF---DFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWV 273
L QF + L T+ T G + + + F L R+MGY+ IQ YIP +L V+LSWV
Sbjct: 218 -LPQFILKEEKELGYCTKHYNT--GKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 274 SFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALME 333
SFWI DA PAR ALGITTVLTMTT S+ +R SLP+VSYV A+D+++ VC LFVFAAL+E
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 334 YATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNN 393
YA +N+ S K+ L + E ++ ++ N+S M
Sbjct: 335 YAAVNFVS-----RQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG----------- 378
Query: 394 SVYWQEFEDTCVYECLDGKDCQSFFC-----CYEECKSGSWRKGRIHIDILELDSYSRVF 448
CL KD + + K G K + +D+ SR
Sbjct: 379 -------------HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAA 425
Query: 449 FPTSFLLFNLVYWVGY 464
FP +FL+FN+ YW+ Y
Sbjct: 426 FPLAFLIFNIFYWITY 441
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 258 bits (658), Expect = 1e-68
Identities = 160/436 (36%), Positives = 234/436 (53%), Gaps = 46/436 (10%)
Query: 42 SQDTDVTLILNKLLRE---YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFF 98
SQ + L+KL+ YD ++RP+ P + +I++NS G ++ M+Y+++IF
Sbjct: 39 SQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFL 98
Query: 99 AQTWTDSRLRFNSTMK-ILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDG 157
Q W DSRL ++ L L+ +M+ IW PD F N K A H +TT N+LLRI +G
Sbjct: 99 RQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNG 158
Query: 158 KILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNS-VEAADQKSW 216
K+LY++RLT+ C + L NFPMD +C + S+GY ++I+ W + V+ A+ +
Sbjct: 159 KVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLT- 217
Query: 217 RLYQF---DFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWV 273
L QF + L T+ T G + + + F L R+MGY+ IQ YIP +L V+LSWV
Sbjct: 218 -LPQFILKEEKELGYCTKHYNT--GKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
Query: 274 SFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALME 333
SFWI DA PAR ALGITTVLTMTT S+ +R SLP+VSYV A+D+++ VC LFVFAAL+E
Sbjct: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
Query: 334 YATLNYYSSCRKPTTTKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNN 393
YA +N+ S K+ L + E ++ ++ N+S M
Sbjct: 335 YAAVNFVS-----RQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG----------- 378
Query: 394 SVYWQEFEDTCVYECLDGKDCQSFFC-----CYEECKSGSWRKGRIHIDILELDSYSRVF 448
CL KD + + K G K + +D+ SR
Sbjct: 379 -------------HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAA 425
Query: 449 FPTSFLLFNLVYWVGY 464
FP +FL+FN+ YW+ Y
Sbjct: 426 FPLAFLIFNIFYWITY 441
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 255 bits (652), Expect = 5e-68
Identities = 160/434 (36%), Positives = 233/434 (53%), Gaps = 60/434 (13%)
Query: 58 YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMK-IL 116
YD ++RP+ P + +I++NS G ++ M+Y+++IF Q W D RL ++ L
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 117 TLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLH 176
L+ +M+ IW PD F N K A H +TT N+LLRI+ +G +LY++RLT+ C + L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 177 NFPMDEHSCPLIFSSYGYPKEEMIYRWRKNS-VEAADQKSWRLYQF---DFMGLRNTTEI 232
NFPMD +C + S+GY ++I+ W+ + V+ A+ + L QF + LR T+
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLT--LPQFLLKEEKDLRYCTKH 234
Query: 233 VTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITT 292
T G + + + F L R+MGY+ IQ YIP +L V+LSWVSFWI DA PAR ALGITT
Sbjct: 235 YNT--GKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITT 292
Query: 293 VLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKT 352
VLTMTT S+ +R SLP+VSYV A+D+++ VC LFVF+AL+EYA +N+ S K
Sbjct: 293 VLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKEL----- 347
Query: 353 TSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTC--VYECLD 410
L + E +L+ +S +D + V F T + CL
Sbjct: 348 --LRFRRKRKNKTEAFALEKFYRFSDMD------------DEVRESRFSFTAYGMGPCLQ 393
Query: 411 GKDCQSFFCCYEECKSGSWRKG----------------RIHID-ILELDSYSRVFFPTSF 453
KD G KG ++ ID ++D+ SR FP +F
Sbjct: 394 AKD-------------GMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAF 440
Query: 454 LLFNLVYWVGYLYL 467
L+FN+ YWV Y L
Sbjct: 441 LIFNIFYWVIYKIL 454
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 254 bits (650), Expect = 9e-68
Identities = 153/421 (36%), Positives = 222/421 (52%), Gaps = 48/421 (11%)
Query: 58 YDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMK-IL 116
YD ++RP+ P + +I++NS G ++ M+Y+++IF Q W D RL +N L
Sbjct: 52 YDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSL 111
Query: 117 TLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLH 176
L+ +M+ IW PD F N K A H ITT N+LLRI +G +LY++R+T+ C + L
Sbjct: 112 DLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLK 171
Query: 177 NFPMDEHSCPLIFSSYGYPKEEMIYRWRKN-SVEAADQKSWRLYQF---DFMGLRNTTEI 232
NFPMD +C + S+GY ++I+ W++ +V+ AD + L QF + LR T+
Sbjct: 172 NFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLT--LPQFILKEEKDLRYCTKH 229
Query: 233 VTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITT 292
T G + + F L R+MGY+ IQ YIP +L V+LSW+SFWI DA PAR LGITT
Sbjct: 230 YNT--GKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITT 287
Query: 293 VLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKT 352
VLTMTT S+ +R SLP+VSYV A+D+++ VC LFVF+AL+EYA +N+ S K +
Sbjct: 288 VLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRR 347
Query: 353 TSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGK 412
H + + + N+S M P CL K
Sbjct: 348 KRRHHKEDE-------AGEGRFNFSAYGMGP-----------------------ACLQAK 377
Query: 413 DCQSFFCCYEE---------CKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVG 463
D S KS + ++D SR+ FP +FL+FN+ YW+
Sbjct: 378 DGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWII 437
Query: 464 Y 464
Y
Sbjct: 438 Y 438
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,736,697
Number of Sequences: 37866
Number of extensions: 761467
Number of successful extensions: 2360
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2188
Number of HSP's gapped (non-prelim): 109
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.