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Search of human proteins with 109715852
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109715852 chromosome 6 open reading frame 204 isoform a
[Homo sapiens]
(805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 1595 0.0
gi|109715849 chromosome 6 open reading frame 204 isoform b [Homo... 964 0.0
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 370 e-102
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 81 4e-15
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 81 4e-15
gi|21735548 centrosomal protein 2 [Homo sapiens] 80 1e-14
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 75 2e-13
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 75 2e-13
gi|71061468 centromere protein E [Homo sapiens] 74 7e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 73 9e-13
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 73 1e-12
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 72 2e-12
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 71 3e-12
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 71 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 71 3e-12
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 71 3e-12
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 71 3e-12
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 71 5e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 6e-12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 70 1e-11
gi|156104908 myosin heavy chain 6 [Homo sapiens] 69 1e-11
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 69 2e-11
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 69 2e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 69 2e-11
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 67 5e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 7e-11
gi|38044112 restin isoform b [Homo sapiens] 67 7e-11
gi|4506751 restin isoform a [Homo sapiens] 67 7e-11
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens] 67 9e-11
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens] 67 9e-11
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 1595 bits (4131), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 60
MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA
Sbjct: 1 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 60
Query: 61 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 120
SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP
Sbjct: 61 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 120
Query: 121 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 180
DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR
Sbjct: 121 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 180
Query: 181 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 240
NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF
Sbjct: 181 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 240
Query: 241 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 300
RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL
Sbjct: 241 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 300
Query: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW
Sbjct: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP
Sbjct: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL
Sbjct: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN
Sbjct: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPML 600
LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPML
Sbjct: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPML 600
Query: 601 DAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK 660
DAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK
Sbjct: 601 DAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK 660
Query: 661 KERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMS 720
KERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMS
Sbjct: 661 KERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMS 720
Query: 721 CCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLR 780
CCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLR
Sbjct: 721 CCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLR 780
Query: 781 RDIDELRTTISDRYAQDMGDNCITQ 805
RDIDELRTTISDRYAQDMGDNCITQ
Sbjct: 781 RDIDELRTTISDRYAQDMGDNCITQ 805
>gi|109715849 chromosome 6 open reading frame 204 isoform b [Homo
sapiens]
Length = 496
Score = 964 bits (2492), Expect = 0.0
Identities = 479/480 (99%), Positives = 480/480 (100%)
Query: 1 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 60
MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA
Sbjct: 1 MWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNHIRRHSIA 60
Query: 61 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 120
SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP
Sbjct: 61 SDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPTAHVMPSNSSASISKLRESLTP 120
Query: 121 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 180
DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR
Sbjct: 121 DGSKWSTSLMQTLGNHSRGEQDSSLDMKDFRPLRKWSSLSKLTAPDNCGQGGTVCREESR 180
Query: 181 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 240
NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF
Sbjct: 181 NGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDF 240
Query: 241 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 300
RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL
Sbjct: 241 RASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWL 300
Query: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW
Sbjct: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP
Sbjct: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEK+
Sbjct: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKV 480
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 370 bits (949), Expect = e-102
Identities = 277/789 (35%), Positives = 429/789 (54%), Gaps = 82/789 (10%)
Query: 40 WQATTVPSNHRNNHIRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSQSLITLPT 99
WQ + R+ R S+A DSGDT IGTSCSD ED +SSG+ F+P +S +T+PT
Sbjct: 33 WQTPVISEPFRSRFSRCSSVA-DSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPT 91
Query: 100 AHVMPSNSSASISKLRES-LTPDGSKWSTS-LMQTLGNHSRGEQDSSLDMKDFRPLRKWS 157
AHVMPS S +K + + P SK S L +++G G D ++
Sbjct: 92 AHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNG---------DLGAMKHSP 142
Query: 158 SLSKLTAPDNCGQGGTVCREESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLED-- 215
LS+ + G NG+E+ + P+ H+ E R D
Sbjct: 143 GLSRDLMYFSGATG--------ENGIEQ------------SWFPAVGHERQEEARKFDIP 182
Query: 216 -KEINKKRSSTLDCKYKFESCSKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFE- 273
E +S+ ++ Y S R R Y LPE+K S FE
Sbjct: 183 SMESTLNQSAMMETLY-----SDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFER 237
Query: 274 ------PPKYLMLGQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQ 327
L LG Q G + + +Q+W + +P E S L+ +QQ
Sbjct: 238 NGPHSNSSGVLPLGLQPAPG--LSKPLPSQVW-----QPSPDTWHPREQSCELSTCRQQ- 289
Query: 328 IEDFRQGSETPMQVLTGS---SRQSYSPGYQ--DFSKWESMLKIKEGLLRQKEIVIDRQK 382
+E R E MQ+ G+ ++ P + ++W S+L E LL++KE++ID+Q+
Sbjct: 290 LELIRLQMEQ-MQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQR 348
Query: 383 QQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP-QYENTSLQTPFSEESVSHSQQ 441
+ I+ L +++R++EL+ A+LG D + LQ Q ENT L+ F++++ + S++
Sbjct: 349 KHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSRE 408
Query: 442 G-EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQ 500
+ E+KL+++E EV + E LK L SEE KK EE++K RD++I++LKKKCQKESEQ
Sbjct: 409 KIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQ 468
Query: 501 NKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQ 560
N+EKQ+RIETLE+YLADLPTL+D Q QS QL+ E K+ LQE + + E LEE + C+
Sbjct: 469 NREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICR 528
Query: 561 DKETQLICQKKKEKELVTTVQSLQ--QKVERCLEDGIRLPMLDAKQLQNENDNLRQQNET 618
+KE QL +++E E + SLQ Q VE +G P ++ + Q D+L+
Sbjct: 529 EKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEG---PEVEMESWQKRYDSLQ----- 580
Query: 619 ASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQ 678
KI++ QQ ++D++ ++QS++ ++++E+ T+Q + EE ++++ +Q+L A+ E Q
Sbjct: 581 --KIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQ 638
Query: 679 TDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVID-QLFKEMSCCLFDLKALCSILNQRA 737
+ L+++ + +Q P D + +L +E++ CL DL+A+CSI+ QRA
Sbjct: 639 NQD---LIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRA 695
Query: 738 QGKEPNLSLLLGIRSMNCSAEETEND-HSTETLTKKLSDVCQLRRDIDELRTTISDRYAQ 796
QG +PNLSLLLGI S ET+ D + + +KL +V QLRRDI++LRTT+SDRYAQ
Sbjct: 696 QGHDPNLSLLLGIHS--AQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQ 753
Query: 797 DMGDNCITQ 805
DMG+NC+TQ
Sbjct: 754 DMGENCVTQ 762
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 80.9 bits (198), Expect = 4e-15
Identities = 80/330 (24%), Positives = 164/330 (49%), Gaps = 34/330 (10%)
Query: 380 RQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTS---LQTPFSEESV 436
++K Q+ E +R+N R Q +L + V+SL+ + + ++ ++ E +
Sbjct: 533 KEKAQLEKTIETLRENSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI 591
Query: 437 SHSQQGEFEQKLASTEKEVLQLNEFLK------QRLSLFSEEKKKLEEKLKTRDRYISSL 490
H E KL+ E E Q+ + L+ +R E LE++ + + I++L
Sbjct: 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Query: 491 KKKCQKES---EQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALID 547
K C+K ++N E +R L+K TLD ++ + QL+ LE++N L E ++
Sbjct: 652 KITCEKIEALEQENSELERENRKLKK------TLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 548 TEKKLEEIK------KQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLD 601
+ +E +K Q Q + +L +K++ K+ + +++ +K ER LE +
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER-LE-------VS 757
Query: 602 AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK 661
+ L EN L++ E ++K I + E+ + +E Q++Q L + K+++ K +E+LEK+
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS-KRLEQLEKE 816
Query: 662 ERNVQRLTKALLENQRQTDETCSLLDQGQE 691
+++++ T L ++++Q ++ L Q E
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Score = 75.9 bits (185), Expect = 1e-13
Identities = 102/424 (24%), Positives = 184/424 (43%), Gaps = 76/424 (17%)
Query: 325 QQQIEDFRQGSETPMQVL----------TGSSRQ----SYSPGYQDFSKWESML--KIKE 368
++ IE R+ SE +++L S RQ S +D K +L IKE
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 369 GLLRQKEIVIDRQ--KQQITHLHER-IRDNELRAQHAMLGHYVNCEDSYVASLQPQYENT 425
+ +I +++ K+++ H E+ R EL + H++ E+ + Q + T
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL----HHLEKENELL-----QKKIT 649
Query: 426 SLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDR 485
+L+ + + E E++ +K + Q SL E + EE L+ R R
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR-R 708
Query: 486 YISSLKKKCQKESE---QNKEKQRRIETLEKYLADLP-TLDDVQSQSLQLQILEEKNKNL 541
+ SLK K ++ +NKE + E L+K L L + + + Q L+ +N+ L
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRL 768
Query: 542 QEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQ--KVERCLEDGIRLPM 599
Q+ L ++ KK+++++ + QD E + +K +EL + + L+Q K + LE
Sbjct: 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE 828
Query: 600 LDAKQLQNENDNLRQQ---------------------NETASKIIDSQQDEIDRM----- 633
D KQL+ EN LRQQ N+T SK I ++ R+
Sbjct: 829 KDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Query: 634 ------------ILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRL---TKALLENQRQ 678
I + +++ L EKL TQ+M +LEK ++++ + LL +++
Sbjct: 889 ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Query: 679 TDET 682
TD++
Sbjct: 949 TDDS 952
Score = 63.5 bits (153), Expect = 7e-10
Identities = 89/421 (21%), Positives = 189/421 (44%), Gaps = 28/421 (6%)
Query: 300 LTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVL-------TGSSRQSYSP 352
L E+ T + + + D W+ +QI + SE P + L T S
Sbjct: 408 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 353 GYQDFSKWESMLKIKEGLLR---QKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVN 409
Q +K L+ + K + ++++ Q+++ E I +NE+ + L + N
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE-ILENEIVQEKQSLQNCQN 526
Query: 410 CEDSYVASLQPQYENT--SLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLS 467
+ + Q E T +L+ + Q+ E + S+ ++ Q++ + R+
Sbjct: 527 LSKDLMKE-KAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA--EARVK 583
Query: 468 LFSEEKKKLEEKLKTRDRYISSL---KKKCQKESEQNKEKQRRIETLEKYLADLPTLDDV 524
+E K L E +K +S + K++ +KE E KEK R E LE L L +++
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL 643
Query: 525 -QSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKET---QLICQKKKEKELVTTV 580
Q + L+I EK + L++ + E++ ++KK + QL +K+ +L
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Query: 581 QSLQQKVE--RCLEDGIRLPMLDAKQLQNENDNLRQQNETA-SKIIDSQQDEIDRMILEI 637
L++ VE +C + L+ K+L++E + L++ E + +++ E+ L+I
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 638 QSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
++ +L K + K +++LE + ++++ + L +N + + L+Q ++ ++S +
Sbjct: 764 ENQ--RLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLE 821
Query: 698 Q 698
Q
Sbjct: 822 Q 822
Score = 62.8 bits (151), Expect = 1e-09
Identities = 93/441 (21%), Positives = 191/441 (43%), Gaps = 52/441 (11%)
Query: 371 LRQKEIVIDRQKQQITHLHERIRDNEL---RAQHAMLGHYVNCEDSYVASLQPQYENTSL 427
LR+K + +D+ + +++ ER+ D E R + + V E L+ Q E T
Sbjct: 315 LREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK--TMLEDQLEGTRA 372
Query: 428 QTPFSEESVSHSQQGEFEQKLASTEKE----VLQLNEFLKQRLSLFSEEKKKLEEKLK-- 481
++ E + Q + KL E E ++ E +++ ++L +K+ ++E L
Sbjct: 373 RSDKLHELEKENLQ--LKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLG 430
Query: 482 ---TRDRYISSLKKKCQKE--SEQNKEKQRRI-------ETLEKYLADL-PTLDDVQSQS 528
+ S L + QK E N+ R+ ++L K + +L T+D V+ +
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 529 LQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE 588
++ +E++N+ L + + E ++ + K+ Q+ + K++ +L T+++L++ E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 589 RCLEDGIRLPMLDAKQLQNENDNLRQQNETAS----KIIDSQQDEIDRMILEIQSMQGKL 644
R I++ + + L +LRQ+++ ++ K I+ + + I E S K+
Sbjct: 551 R----QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 645 SKEKLTTQKMMEELEKKERNVQRLTKAL----LENQRQTDETCSLLDQGQEPDQSRQQTV 700
EK +K +E ++K + L L EN+ + +L ++ + Q+
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENS 666
Query: 701 LSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSA--- 757
+R L FK ++ F L+ S+ + +Q E NL L + S+ C++
Sbjct: 667 ELERENRKLKKTLDSFKNLT---FQLE---SLEKENSQLDEENLELRRNVESLKCASMKM 720
Query: 758 -----EETENDHSTETLTKKL 773
E E + E L K L
Sbjct: 721 AQLQLENKELESEKEQLKKGL 741
Score = 60.5 bits (145), Expect = 6e-09
Identities = 78/340 (22%), Positives = 147/340 (43%), Gaps = 47/340 (13%)
Query: 433 EESVSHSQQGEFEQKLASTEKEVLQLNE----FLKQRLSLFSEEKKKLEEKLKTRDRYIS 488
E+S S+ E KL ST K+ L++ E L+ RL + ++L ++LKT +
Sbjct: 946 EQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1005
Query: 489 SLKKKCQKE----------SEQNKEKQRRIETLEKYLADLPTLDDV-----------QSQ 527
+LK++ +E E NK ++ ET + L L +V Q+
Sbjct: 1006 ALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQAL 1065
Query: 528 SLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKV 587
QL+ LE +N NLQ ++ +++ +++Q +TQ + + L + SL +
Sbjct: 1066 KTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Query: 588 ERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMIL----EIQSMQGK 643
+ L + L+NEN+++ ++ E + DS + +++ L + +
Sbjct: 1126 AQLL--------IQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1177
Query: 644 LSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEP---DQSRQQTV 700
+SK T + + LE + R+++ LL+ + Q ++ +L QE + +TV
Sbjct: 1178 ISKHG-TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETV 1236
Query: 701 LSK-RPLFDLT-----VIDQLFKEMSCCLFDLKALCSILN 734
++ + L QL KE D K L S+LN
Sbjct: 1237 AAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLN 1276
Score = 42.4 bits (98), Expect = 0.002
Identities = 78/381 (20%), Positives = 169/381 (44%), Gaps = 45/381 (11%)
Query: 426 SLQTPFSEESVSHSQQGEFEQK--LASTEKEVL--QLNEFLKQRLSLFSEEKKKLEEKLK 481
++Q EE + Q +F+ K +A+ +EV Q N F Q + + ++ +E LK
Sbjct: 132 AVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLK 191
Query: 482 TRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNL 541
++ L + + SE E + L +L + S ++ E + ++L
Sbjct: 192 NMALHLKRLIDERDEHSETIIELSEERDGLH-FLPHASSSAQSPCGSPGMKRTESR-QHL 249
Query: 542 QEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLD 601
L D + K+ ++++ ++K QL+ K++ +++ ++ LQQ+ L D
Sbjct: 250 SVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDA-----RS 304
Query: 602 AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK 661
A+ ++E D LR++ K ++S+ + +I+ + ++ + K Q ++E
Sbjct: 305 ARMYRDELDALREKAVRVDK-LESEVSRYKERLHDIEFYKARVEELKEDNQVLLE----- 358
Query: 662 ERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSC 721
TK +LE+ Q + T + D+ E ++ Q K L D+ ++ ++M
Sbjct: 359 -------TKTMLED--QLEGTRARSDKLHELEKENLQL---KAKLHDM----EMERDMDR 402
Query: 722 CLFDLKALCSILNQRAQGKEPNLSLLLG--IRSMNCSAEETE----------NDHSTETL 769
+ ++ + AQ + + SL LG + ++ ++E +E N+ ++ L
Sbjct: 403 KKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462
Query: 770 TKKLSDVCQLRRDIDELRTTI 790
K + L + ++ELRTT+
Sbjct: 463 LKLEMENQSLTKTVEELRTTV 483
Score = 34.7 bits (78), Expect = 0.36
Identities = 48/238 (20%), Positives = 107/238 (44%), Gaps = 21/238 (8%)
Query: 361 ESMLKIKEGLLRQKEIVI-DRQKQQITHLHERIRDNELRAQHAMLG--------HYVNCE 411
ES++K +E L + +I D +K ++ H + L ++H L + + E
Sbjct: 1140 ESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 1199
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE 471
D Y L+ + + L+ E + + + +A+ K++ N+ L S +
Sbjct: 1200 DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1259
Query: 472 EKKKLEEKLKTRDRYISSLK-KKCQKESEQNKEKQR---------RIETLEKYLADLPTL 521
E + L+ K +++ K ++ + E+E +K K++ ++ + L+ L
Sbjct: 1260 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1319
Query: 522 DDVQSQSL--QLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELV 577
+ +++ L Q+Q L +N+ L E ++++ ++Q DK +L QK+K +E +
Sbjct: 1320 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1377
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 80.9 bits (198), Expect = 4e-15
Identities = 80/330 (24%), Positives = 164/330 (49%), Gaps = 34/330 (10%)
Query: 380 RQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTS---LQTPFSEESV 436
++K Q+ E +R+N R Q +L + V+SL+ + + ++ ++ E +
Sbjct: 533 KEKAQLEKTIETLRENSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI 591
Query: 437 SHSQQGEFEQKLASTEKEVLQLNEFLK------QRLSLFSEEKKKLEEKLKTRDRYISSL 490
H E KL+ E E Q+ + L+ +R E LE++ + + I++L
Sbjct: 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Query: 491 KKKCQKES---EQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALID 547
K C+K ++N E +R L+K TLD ++ + QL+ LE++N L E ++
Sbjct: 652 KITCEKIEALEQENSELERENRKLKK------TLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 548 TEKKLEEIK------KQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLD 601
+ +E +K Q Q + +L +K++ K+ + +++ +K ER LE +
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER-LE-------VS 757
Query: 602 AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK 661
+ L EN L++ E ++K I + E+ + +E Q++Q L + K+++ K +E+LEK+
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS-KRLEQLEKE 816
Query: 662 ERNVQRLTKALLENQRQTDETCSLLDQGQE 691
+++++ T L ++++Q ++ L Q E
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Score = 78.6 bits (192), Expect = 2e-14
Identities = 105/433 (24%), Positives = 187/433 (43%), Gaps = 76/433 (17%)
Query: 325 QQQIEDFRQGSETPMQVL----------TGSSRQ----SYSPGYQDFSKWESML--KIKE 368
++ IE R+ SE +++L S RQ S +D K +L IKE
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 369 GLLRQKEIVIDRQ--KQQITHLHER-IRDNELRAQHAMLGHYVNCEDSYVASLQPQYENT 425
+ +I +++ K+++ H E+ R EL + H++ E+ + Q + T
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL----HHLEKENELL-----QKKIT 649
Query: 426 SLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDR 485
+L+ + + E E++ +K + Q SL E + EE L+ R R
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR-R 708
Query: 486 YISSLKKKCQKESE---QNKEKQRRIETLEKYLADLP-TLDDVQSQSLQLQILEEKNKNL 541
+ SLK K ++ +NKE + E L+K L L + + + Q L+ +N+ L
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRL 768
Query: 542 QEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQ--KVERCLEDGIRLPM 599
Q+ L ++ KK+++++ + QD E + +K +EL + + L+Q K + LE
Sbjct: 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE 828
Query: 600 LDAKQLQNENDNLRQQ---------------------NETASKIIDSQQDEIDRM----- 633
D KQL+ EN LRQQ N+T SK I ++ R+
Sbjct: 829 KDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Query: 634 ------------ILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRL---TKALLENQRQ 678
I + +++ L EKL TQ+M +LEK ++++ + LL +++
Sbjct: 889 ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Query: 679 TDETCSLLDQGQE 691
TD+ LL+ E
Sbjct: 949 TDDRYKLLESKLE 961
Score = 63.5 bits (153), Expect = 7e-10
Identities = 89/421 (21%), Positives = 189/421 (44%), Gaps = 28/421 (6%)
Query: 300 LTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVL-------TGSSRQSYSP 352
L E+ T + + + D W+ +QI + SE P + L T S
Sbjct: 408 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 353 GYQDFSKWESMLKIKEGLLR---QKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVN 409
Q +K L+ + K + ++++ Q+++ E I +NE+ + L + N
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE-ILENEIVQEKQSLQNCQN 526
Query: 410 CEDSYVASLQPQYENT--SLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLS 467
+ + Q E T +L+ + Q+ E + S+ ++ Q++ + R+
Sbjct: 527 LSKDLMKE-KAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA--EARVK 583
Query: 468 LFSEEKKKLEEKLKTRDRYISSL---KKKCQKESEQNKEKQRRIETLEKYLADLPTLDDV 524
+E K L E +K +S + K++ +KE E KEK R E LE L L +++
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL 643
Query: 525 -QSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKET---QLICQKKKEKELVTTV 580
Q + L+I EK + L++ + E++ ++KK + QL +K+ +L
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Query: 581 QSLQQKVE--RCLEDGIRLPMLDAKQLQNENDNLRQQNETA-SKIIDSQQDEIDRMILEI 637
L++ VE +C + L+ K+L++E + L++ E + +++ E+ L+I
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 638 QSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
++ +L K + K +++LE + ++++ + L +N + + L+Q ++ ++S +
Sbjct: 764 ENQ--RLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLE 821
Query: 698 Q 698
Q
Sbjct: 822 Q 822
Score = 62.8 bits (151), Expect = 1e-09
Identities = 93/441 (21%), Positives = 191/441 (43%), Gaps = 52/441 (11%)
Query: 371 LRQKEIVIDRQKQQITHLHERIRDNEL---RAQHAMLGHYVNCEDSYVASLQPQYENTSL 427
LR+K + +D+ + +++ ER+ D E R + + V E L+ Q E T
Sbjct: 315 LREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK--TMLEDQLEGTRA 372
Query: 428 QTPFSEESVSHSQQGEFEQKLASTEKE----VLQLNEFLKQRLSLFSEEKKKLEEKLK-- 481
++ E + Q + KL E E ++ E +++ ++L +K+ ++E L
Sbjct: 373 RSDKLHELEKENLQ--LKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLG 430
Query: 482 ---TRDRYISSLKKKCQKE--SEQNKEKQRRI-------ETLEKYLADL-PTLDDVQSQS 528
+ S L + QK E N+ R+ ++L K + +L T+D V+ +
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 529 LQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE 588
++ +E++N+ L + + E ++ + K+ Q+ + K++ +L T+++L++ E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 589 RCLEDGIRLPMLDAKQLQNENDNLRQQNETAS----KIIDSQQDEIDRMILEIQSMQGKL 644
R I++ + + L +LRQ+++ ++ K I+ + + I E S K+
Sbjct: 551 R----QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 645 SKEKLTTQKMMEELEKKERNVQRLTKAL----LENQRQTDETCSLLDQGQEPDQSRQQTV 700
EK +K +E ++K + L L EN+ + +L ++ + Q+
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENS 666
Query: 701 LSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSA--- 757
+R L FK ++ F L+ S+ + +Q E NL L + S+ C++
Sbjct: 667 ELERENRKLKKTLDSFKNLT---FQLE---SLEKENSQLDEENLELRRNVESLKCASMKM 720
Query: 758 -----EETENDHSTETLTKKL 773
E E + E L K L
Sbjct: 721 AQLQLENKELESEKEQLKKGL 741
Score = 61.6 bits (148), Expect = 3e-09
Identities = 95/422 (22%), Positives = 174/422 (41%), Gaps = 54/422 (12%)
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
+ EN +LQ E +S + + E++ S E+E QL + KQ +E K+L ++
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ----LEKENKRLRQQA 845
Query: 481 KTRDR-------YISSLKKK---CQKESEQNKEKQRRIETLEKYLADL---PTLDDVQSQ 527
+ +D I +L+K+ KE KE R++ LEK +L T+D
Sbjct: 846 EIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLV 905
Query: 528 SLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKV 587
+L+ ++ EK K Q+ D EK E++K +KE L ++ + L+ +
Sbjct: 906 TLREDLVSEKLKT-QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTL 964
Query: 588 ERCLE-DGIRLPMLDAK--QLQNENDNLRQQNETASKIIDS--QQDEIDRMILEIQSMQG 642
++ LE ++ L+A+ + N N LRQ+ +T K ++ Q+ + +RM+ + G
Sbjct: 965 KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG 1024
Query: 643 ----------KLSKEKLTTQKMMEELEKKERNVQRLTKAL------LENQRQTDETCSLL 686
+ ++E L + + E+E+ +Q +AL LE Q + L
Sbjct: 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1084
Query: 687 DQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSL 746
Q Q Q T L + L V + S L + A +L Q++ + N S+
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNA-KLQVENSTLNSQSTSLMNQNA--QLLIQQSSLENENESV 1141
Query: 747 LLGIRSMNCSAEETENDHST------------ETLTKKLSDVCQLRRDIDELRTTISDRY 794
+ + + DH E+L K + ++++ + DRY
Sbjct: 1142 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1201
Query: 795 AQ 796
Q
Sbjct: 1202 NQ 1203
Score = 59.7 bits (143), Expect = 1e-08
Identities = 136/672 (20%), Positives = 262/672 (38%), Gaps = 138/672 (20%)
Query: 177 EESRNGLEKIGKA-KALTSQLRTIGPSCLHDSMEMLRLEDKEI---NKKRSSTLDC---- 228
EE N L + K + L ++ + +C + +E L E+ E+ N+K TLD
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKTLDSFKNL 685
Query: 229 KYKFESCSKEDFRASSSTLR-RQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGG 287
++ ES KE+ + L R+ V+ A + + ++ E K +Q G
Sbjct: 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK-----EQLKKG 740
Query: 288 VPIQPSVRTQMWLTEQLRTN----PLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLT 343
+ + ++ TE+L + +E + + + + + QQ+E Q E Q L
Sbjct: 741 LEL---LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQ 797
Query: 344 GSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIR------DNEL 397
+ + + SK L+ + L Q+ +++ K+Q+ ++R+R D L
Sbjct: 798 KNLEE-----LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Query: 398 RAQHAMLGHYV---------------NC----------------------------EDSY 414
+ +G+ +C ED
Sbjct: 853 EENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLV 912
Query: 415 VASLQPQYENTSLQT--------PFSEESVSHSQQGE------FEQKLASTEKEVLQLNE 460
L+ Q N L+ ++E + H +Q E KL ST K+ L++ E
Sbjct: 913 SEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKE 972
Query: 461 ----FLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKE----------SEQNKEKQR 506
L+ RL + ++L ++LKT + +LK++ +E E NK ++
Sbjct: 973 EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE 1032
Query: 507 RIETLEKYLADLPTLDDV-----------QSQSLQLQILEEKNKNLQEALIDTEKKLEEI 555
ET + L L +V Q+ QL+ LE +N NLQ ++ +++ +
Sbjct: 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Query: 556 KKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQ 615
++Q +TQ + + L + SL + + L + L+NEN+++ ++
Sbjct: 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLL--------IQQSSLENENESVIKE 1144
Query: 616 NETASKIIDSQQDEIDRMIL----EIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKA 671
E + DS + +++ L + + +SK T + + LE + R+++
Sbjct: 1145 REDLKSLYDSLIKDHEKLELLHERQASEYESLISKHG-TLKSAHKNLEVEHRDLEDRYNQ 1203
Query: 672 LLENQRQTDETCSLLDQGQEP---DQSRQQTVLSK-RPLFDLT-----VIDQLFKEMSCC 722
LL+ + Q ++ +L QE + +TV ++ + L QL KE
Sbjct: 1204 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVL 1263
Query: 723 LFDLKALCSILN 734
D K L S+LN
Sbjct: 1264 QTDHKNLKSLLN 1275
Score = 42.4 bits (98), Expect = 0.002
Identities = 78/381 (20%), Positives = 169/381 (44%), Gaps = 45/381 (11%)
Query: 426 SLQTPFSEESVSHSQQGEFEQK--LASTEKEVL--QLNEFLKQRLSLFSEEKKKLEEKLK 481
++Q EE + Q +F+ K +A+ +EV Q N F Q + + ++ +E LK
Sbjct: 132 AVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLK 191
Query: 482 TRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNL 541
++ L + + SE E + L +L + S ++ E + ++L
Sbjct: 192 NMALHLKRLIDERDEHSETIIELSEERDGLH-FLPHASSSAQSPCGSPGMKRTESR-QHL 249
Query: 542 QEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLD 601
L D + K+ ++++ ++K QL+ K++ +++ ++ LQQ+ L D
Sbjct: 250 SVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDA-----RS 304
Query: 602 AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK 661
A+ ++E D LR++ K ++S+ + +I+ + ++ + K Q ++E
Sbjct: 305 ARMYRDELDALREKAVRVDK-LESEVSRYKERLHDIEFYKARVEELKEDNQVLLE----- 358
Query: 662 ERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSC 721
TK +LE+ Q + T + D+ E ++ Q K L D+ ++ ++M
Sbjct: 359 -------TKTMLED--QLEGTRARSDKLHELEKENLQL---KAKLHDM----EMERDMDR 402
Query: 722 CLFDLKALCSILNQRAQGKEPNLSLLLG--IRSMNCSAEETE----------NDHSTETL 769
+ ++ + AQ + + SL LG + ++ ++E +E N+ ++ L
Sbjct: 403 KKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462
Query: 770 TKKLSDVCQLRRDIDELRTTI 790
K + L + ++ELRTT+
Sbjct: 463 LKLEMENQSLTKTVEELRTTV 483
Score = 34.7 bits (78), Expect = 0.36
Identities = 48/238 (20%), Positives = 107/238 (44%), Gaps = 21/238 (8%)
Query: 361 ESMLKIKEGLLRQKEIVI-DRQKQQITHLHERIRDNELRAQHAMLG--------HYVNCE 411
ES++K +E L + +I D +K ++ H + L ++H L + + E
Sbjct: 1139 ESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 1198
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE 471
D Y L+ + + L+ E + + + +A+ K++ N+ L S +
Sbjct: 1199 DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1258
Query: 472 EKKKLEEKLKTRDRYISSLK-KKCQKESEQNKEKQR---------RIETLEKYLADLPTL 521
E + L+ K +++ K ++ + E+E +K K++ ++ + L+ L
Sbjct: 1259 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1318
Query: 522 DDVQSQSL--QLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELV 577
+ +++ L Q+Q L +N+ L E ++++ ++Q DK +L QK+K +E +
Sbjct: 1319 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 79.7 bits (195), Expect = 1e-14
Identities = 113/474 (23%), Positives = 207/474 (43%), Gaps = 52/474 (10%)
Query: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
T QL E + E+ + A +++ + + E +Q + RQ + Q S
Sbjct: 707 TTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVE-RDRQDLAEQLQGLSSA 765
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
+ +L+ +Q+ VI+ K Q+ + + +A+ + G V C + + +
Sbjct: 766 KELLESSLFEAQQQNSVIEVTKGQLEVQIQTVT----QAKEVIQGE-VRCLKLELDTERS 820
Query: 421 QYENTSLQTPFSEESVSHSQQGE--FEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE 478
Q E + + + Q+G+ EQ+ A+ EKEV QL E ++ S +E K E
Sbjct: 821 QAEQE--RDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALE 878
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
L+ ++K + E KE+Q +E ++ + T +S Q+Q+ EK
Sbjct: 879 SLE---------REKMELEMRL-KEQQTEMEAIQAQREEERT--QAESALCQMQLETEKE 926
Query: 539 K-NLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRL 597
+ +L E L+ T+K+L + +Q + + QK KE+E +Q+ Q+ +R L++ R
Sbjct: 927 RVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQ 986
Query: 598 PMLDAKQLQNENDNLRQQNETASKIIDSQQDEI----DRMILEIQSMQGKLSKEKLTTQK 653
D LQ E+ +L Q K ++ + ++ D L Q +Q KL +E +
Sbjct: 987 HRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKL-RETQEYNR 1045
Query: 654 MMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVID 713
+ +ELE+++ + LT +L+E +++ L QE D RQQ +L+ +
Sbjct: 1046 IQKELEREKAS---LTLSLMEKEQR-------LLVLQEADSIRQQ---------ELSALR 1086
Query: 714 QLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTE 767
Q +E +L A +L Q + KE + + EE E H TE
Sbjct: 1087 QDMQEAQGEQKELSAQMELLRQEVKEKEADF-----LAQEAQLLEELEASHITE 1135
Score = 67.0 bits (162), Expect = 7e-11
Identities = 73/355 (20%), Positives = 162/355 (45%), Gaps = 22/355 (6%)
Query: 364 LKIKEGLLRQKEIVIDRQKQQITHLHERI--RDNELRAQHAMLGHYVNCEDSYVASLQPQ 421
++ ++ L+++ E + Q+ +THL + R EL+AQ + + + LQ +
Sbjct: 1569 MECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQER 1628
Query: 422 YENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK-------QRLSLFSEEKK 474
+ Q EE Q+ Q L ++E++ E ++ ++ + E+ +
Sbjct: 1629 DQEVKSQREQIEEL--QRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLE 1686
Query: 475 KLEEKLKTRDRYISSLKKKCQKESEQNK--EKQRR--IETLEKYLADLPTLDDVQSQSLQ 530
+++ L+ R R +++ ++ Q+ +E+ K K +R +E ++ L D +V+ Q
Sbjct: 1687 QIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEK--EVECQQEH 1744
Query: 531 LQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERC 590
+ L+E L++ L +K+ E +E +++ +++ +E + +Q ++
Sbjct: 1745 IHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQ 1804
Query: 591 LEDGIR-LPMLDAK--QLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKE 647
L++ R L D + LQ E + Q E + D+ Q +++ + ++ G+L
Sbjct: 1805 LDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDH 1864
Query: 648 KLTTQKMMEELEKKERNVQRLTKAL--LENQRQTDETCSLLDQGQEPDQSRQQTV 700
K +++ EEL + R VQ L + L L + + E L Q Q +Q+++ V
Sbjct: 1865 KEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEV 1919
Score = 59.7 bits (143), Expect = 1e-08
Identities = 75/378 (19%), Positives = 158/378 (41%), Gaps = 49/378 (12%)
Query: 371 LRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHY-VNCEDSYVASLQPQYEN----- 424
L +K+ +I+ Q+ Q+ L +++ E A H+ + C+ + L+ Q E
Sbjct: 1531 LEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVAL 1590
Query: 425 TSLQTPFSEES----VSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE---EKKKLE 477
T L E S SQ + E +E+ + ++ +K + E +K+ L
Sbjct: 1591 THLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLT 1650
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSL--QLQILE 535
+ L+ RD+ + K++ Q +Q + R+ + LE+ L + + + L Q Q+++
Sbjct: 1651 QDLERRDQELMLQKERIQVLEDQ---RTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQ 1707
Query: 536 EKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE----RCL 591
E+ + + LE +K +DKE ++ CQ++ EL L+Q+++ +
Sbjct: 1708 ERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG 1767
Query: 592 EDGIRLPMLDAK--QLQNENDNLRQQNETASKIIDSQQDEIDRMILE------------- 636
E + L + + LQ + R+Q E + + SQ DE R + +
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Query: 637 ------------IQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCS 684
++QG L + +T ++ EL+ + +RL + L R+
Sbjct: 1828 QAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEE 1887
Query: 685 LLDQGQEPDQSRQQTVLS 702
+L + + +++ +L+
Sbjct: 1888 VLGDLRAESREQEKALLA 1905
Score = 51.6 bits (122), Expect = 3e-06
Identities = 87/433 (20%), Positives = 176/433 (40%), Gaps = 74/433 (17%)
Query: 347 RQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGH 406
++ S ++ SKWE E L + + + L R+R EL+ A
Sbjct: 1291 QRQLSQNQEEKSKWEGKQNSLESELMELH-------ETMASLQSRLRRAELQRMEAQGER 1343
Query: 407 YVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRL 466
+ + +L Q E+ LQ E S G E+ L + + NE ++
Sbjct: 1344 ELL--QAAKENLTAQVEH--LQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESE- 1398
Query: 467 SLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQS 526
E + L+E+ + + +L++ ++ E++ +ETL + +L ++Q
Sbjct: 1399 ---RERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQK 1455
Query: 527 QSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQK 586
+L+L L+ K +N + L +++++E++K C+ E L VQ +QK
Sbjct: 1456 AALELLSLDLKKRNQEVDL--QQEQIQELEK----------CRSVLE-HLPMAVQEREQK 1502
Query: 587 VERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGK--- 643
+ + +Q++ L + ET +++ Q E+++ I+S +G+
Sbjct: 1503 L-----------TVQREQIR----ELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQD 1547
Query: 644 LSKEKLTTQKMMEELEKKERNVQRLTKAL--LENQRQTDETCSLLDQGQEPDQSRQQTVL 701
L K+ +T + + ELE+ ++ K + LE QR+T Q V
Sbjct: 1548 LKKQLVTLECLALELEENHHKMECQQKLIKELEGQRET------------------QRVA 1589
Query: 702 SKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEE-- 759
DL Q + S + DL++ ++L + Q ++ ++S EE
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQE------VKSQREQIEELQ 1643
Query: 760 TENDHSTETLTKK 772
+ +H T+ L ++
Sbjct: 1644 RQKEHLTQDLERR 1656
Score = 47.4 bits (111), Expect = 5e-05
Identities = 62/272 (22%), Positives = 118/272 (43%), Gaps = 19/272 (6%)
Query: 437 SHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKK--- 493
+ SQ +++ A E LQ K +L +E+ LE+ +R S+ +
Sbjct: 1947 AESQSSRHQEEAARARAEALQ-EALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASL 2005
Query: 494 --CQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKK 551
CQ S Q E+ RI+ E DL +DVQ L +E+ ++ QE EK
Sbjct: 2006 DACQAHSRQ-LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 2064
Query: 552 LEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDN 611
L + ++ +E Q + Q+++E+E+ QS+++ ++L + +Q E
Sbjct: 2065 LAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRE---------LQLTLAQKEQEILELRE 2115
Query: 612 LRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKA 671
+Q+N + + ++ L++ S++ +L +E Q + + E +E + +
Sbjct: 2116 TQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQD 2175
Query: 672 LLENQRQTDETCSLLDQGQEPDQSRQQTVLSK 703
L + QT + S L QE Q +VL +
Sbjct: 2176 LALSLAQTKASVSSL---QEVAMFLQASVLER 2204
Score = 46.2 bits (108), Expect = 1e-04
Identities = 85/381 (22%), Positives = 158/381 (41%), Gaps = 61/381 (16%)
Query: 342 LTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQH 401
L G S Q G ++ + E L ++E R +E+++ + +Q L E I E
Sbjct: 498 LQGDSAQ----GQKEEQQEELHLAVRERE-RLQEMLMGLEAKQSESLSELITLREALESS 552
Query: 402 AMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLA--STEKEVLQLN 459
+ G + E + V + + E + + SE ++ ++ + S E L L+
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK-TEVADLRAAAVKLSALNEALALD 611
Query: 460 EF-LKQRLSLFSEEKKKLEEKLKTRDRYISSLK---KKCQKESEQNKEKQRRIETLEKYL 515
+ L Q+L EE + + +++ ++ ++L+ + +K E EK +E
Sbjct: 612 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEA----- 666
Query: 516 ADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKE 575
QLQ EE LQ L D +++ EEI+K+ + Q ++
Sbjct: 667 --------------QLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQ-------QEA 705
Query: 576 LVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMIL 635
T ++ L Q+ +R E + A+ +Q + +R E A+ + Q E DR L
Sbjct: 706 ATTQLEQLHQEAKRQEE-------VLARAVQEKEALVR---EKAALEVRLQAVERDRQDL 755
Query: 636 EIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQT----------DETCSL 685
+ +QG S ++L + E +++ +V +TK LE Q QT + C
Sbjct: 756 -AEQLQGLSSAKELLESSLFE--AQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLK 812
Query: 686 LDQGQEPDQSRQQTVLSKRPL 706
L+ E Q+ Q+ + R L
Sbjct: 813 LELDTERSQAEQERDAAARQL 833
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/256 (17%), Positives = 111/256 (43%), Gaps = 16/256 (6%)
Query: 443 EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNK 502
+ Q+LA ++ V L+Q+ + EE K L ++L+ L + + Q
Sbjct: 404 DLRQQLAGCQEAV----NLLQQQHDQWEEEGKALRQRLQ-------KLTGERDTLAGQTV 452
Query: 503 EKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDK 562
+ Q +++L K L + Q QL++LE++ L+ ++ + + + + Q +++
Sbjct: 453 DLQGEVDSLSKERELLQKAREELRQ--QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQ 510
Query: 563 ETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRL-PMLDAKQLQNENDNLRQQNETASK 621
+ +L ++ + L + L+ K L + I L L++ L E + LRQ+ +
Sbjct: 511 QEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHL--EGELLRQEQTEVTA 568
Query: 622 IIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDE 681
+ + I + +++ +++ + K+ E + L + LL+ + +
Sbjct: 569 ALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQS 628
Query: 682 TCSLLDQGQEPDQSRQ 697
CS ++ ++ + Q
Sbjct: 629 VCSRMEAAEQARNALQ 644
Score = 37.4 bits (85), Expect = 0.056
Identities = 47/201 (23%), Positives = 89/201 (44%), Gaps = 45/201 (22%)
Query: 533 ILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEK---------------ELV 577
+L ++ + L+E L DTE + ++ + QD + QL Q ++EK EL
Sbjct: 1261 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQL-SQNQEEKSKWEGKQNSLESELMELH 1319
Query: 578 TTVQSLQQKVERCLEDGIRLPMLDA----KQLQNENDNLRQQNE-TASKIIDSQQDEIDR 632
T+ SLQ ++ R L ++A + LQ +NL Q E + +++++
Sbjct: 1320 ETMASLQSRLRRA-----ELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAA 1374
Query: 633 MILE---------IQSMQGKLSKEKLTTQKMMEELEKK-------ERNVQRLTKALLENQ 676
ILE ++ ++ E+ Q + E+ E K + N+ LT+ L E +
Sbjct: 1375 GILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAERE 1434
Query: 677 RQTDETCSLLDQGQEPDQSRQ 697
+ + +L Q QE ++ R+
Sbjct: 1435 EEVE---TLRGQIQELEKQRE 1452
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 75.1 bits (183), Expect = 2e-13
Identities = 104/455 (22%), Positives = 198/455 (43%), Gaps = 71/455 (15%)
Query: 359 KWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIR---DNELRAQHAMLGHYVNCEDSYV 415
++ L KE L+ Q + R KQ T E ++ + E++A++A L H +
Sbjct: 1292 EFSRQLDEKEALVSQ----LSRGKQAFTQQIEELKRQLEEEIKAKNA-LAHALQSSRHDC 1346
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSE 471
L+ QYE EE S + E ++ L+ EV Q + QR E
Sbjct: 1347 DLLREQYE---------EEQES---KAELQRALSKANTEVAQWRTKYETDAIQRTEELEE 1394
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
KKKL ++L+ + ++ ++ KC + + Q +E L + DV+ +
Sbjct: 1395 AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDL---------MLDVERTNAAC 1445
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
L++K +N +K L E K++C++ +L +K+ + L T + ++ E L
Sbjct: 1446 AALDKKQRNF-------DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 592 EDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTT 651
+ + L+ EN NL+Q+ + Q E + I E++ ++ ++ +EK
Sbjct: 1499 D--------QLETLKRENKNLQQEISD----LTEQIAEGGKRIHELEKIKKQVEQEKCEL 1546
Query: 652 QKMMEE----LEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ---QTVLSKR 704
Q +EE LE +E + R+ L NQ +++ + ++ +E DQ ++ + V S +
Sbjct: 1547 QAALEEAEASLEHEEGKILRIQLEL--NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 705 PLFDLTVID-----QLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEE 759
D + +L K+M L +++ + N+ A N GI +
Sbjct: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK-DTQIHL 1663
Query: 760 TENDHSTETLTKKLSDVCQ----LRRDIDELRTTI 790
+ S E L ++L+ V + L+ +I+ELR T+
Sbjct: 1664 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698
Score = 64.7 bits (156), Expect = 3e-10
Identities = 77/349 (22%), Positives = 151/349 (43%), Gaps = 51/349 (14%)
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
EK++L+EKLK ++ IS+L+ K + E + Q++I+ L+ + +L ++++++
Sbjct: 1078 EKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELE--EEIEAERASR 1135
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
E++ +L L + ++LEE Q+ KK+E E QK+ R L
Sbjct: 1136 AKAEKQRSDLSRELEEISERLEEAGGA---TSAQIEMNKKREAEF--------QKMRRDL 1184
Query: 592 EDG----------IRLPMLDA-KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSM 640
E+ +R D+ +L + DNL++ + K + EID + ++++
Sbjct: 1185 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETV 1244
Query: 641 ---QGKLSKEKLTTQKMMEELEKKERNVQRLTKALL-----------ENQRQTDETCSLL 686
+G L K T + + EL+ KE QRL L E RQ DE +L+
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV 1304
Query: 687 DQGQEPDQSRQQTV--LSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNL 744
Q Q+ Q + L ++ ++ + L + D C +L ++ + ++ +
Sbjct: 1305 SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD----CDLLREQYEEEQESK 1360
Query: 745 SLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDR 793
+ L A N + TK +D Q +++E + ++ R
Sbjct: 1361 AELQ-------RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402
Score = 62.0 bits (149), Expect = 2e-09
Identities = 103/484 (21%), Positives = 200/484 (41%), Gaps = 68/484 (14%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQ---HAMLGHYVNCEDSYVAS 417
E KIK+ L + + + +++ +T L E+ D +L+ Q + C+
Sbjct: 860 EEFQKIKDELAKSEAKRKELEEKMVTLLKEK-NDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 477
+Q + + + +E +++ ++KL E+ + + L+ L+ +EK E
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 978
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEK 537
K+K ++ L + K +++ K Q A TLDD+Q++ ++ L +
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKEKKALQE---------AHQQTLDDLQAEEDKVNTLTKA 1029
Query: 538 NKNLQEALIDTEKKLEEIKKQCQD-----------------------KETQLICQKKKEK 574
L++ + D E LE+ KK D E Q + +K K+K
Sbjct: 1030 KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKK 1089
Query: 575 ELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQ--QNETASKI-IDSQQDEID 631
E + +LQ K+E GI+L K+LQ + L + + E AS+ + Q+ ++
Sbjct: 1090 EF--EISNLQSKIEDEQALGIQL-QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 632 RMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETC-------- 683
R E++ + +L + T +E +K+E Q++ + L E Q + T
Sbjct: 1147 R---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 684 -SLLDQGQEPDQ-SRQQTVLSKRPLFDLTVIDQL---FKEMSCCLFDLKALCSILNQR-- 736
S+ + G++ D R + L K ID L + +S +L+ +C L +
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 737 -AQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRR-------DIDELRT 788
+ KE L+ + +TE+ + L +K + V QL R I+EL+
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323
Query: 789 TISD 792
+ +
Sbjct: 1324 QLEE 1327
Score = 57.4 bits (137), Expect = 5e-08
Identities = 79/355 (22%), Positives = 158/355 (44%), Gaps = 31/355 (8%)
Query: 447 KLASTEKEVLQLNEF---LKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKE 503
K A TEKE+ + E +K L+ ++K+LEEK+ T + + L+ + Q E+E +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 504 KQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKE 563
+ R + L K L ++ + + + EE N L E + E+KK D E
Sbjct: 907 AEERCDQLIKTKIQLEA--KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 564 TQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKII 623
L K EKE T + KV+ E+ L AK L E L++ ++ +
Sbjct: 965 LTL---AKVEKEKHAT----ENKVKNLTEEMAGLDETIAK-LTKEKKALQEAHQQTLDDL 1016
Query: 624 DSQQDEID-------RMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQ 676
+++D+++ ++ ++ ++G L +EK K+ +LE+ +R ++ K E+
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK----KLRMDLERAKRKLEGDLKLAQESI 1072
Query: 677 RQTDETCSLLDQ---GQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDL-KALCSI 732
+ LD+ +E + S Q+ + + + + KE+ + +L + + +
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQ-LQKKIKELQARIEELEEEIEAE 1131
Query: 733 LNQRAQGKEPNLSLLLGIRSMNCSAEETENDHST--ETLTKKLSDVCQLRRDIDE 785
RA+ ++ L + ++ EE S E K+ ++ ++RRD++E
Sbjct: 1132 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1186
Score = 56.6 bits (135), Expect = 9e-08
Identities = 108/547 (19%), Positives = 221/547 (40%), Gaps = 60/547 (10%)
Query: 178 ESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKK-------RSSTLDC-- 228
ES ++ + +AL SQL + E+ R ++EI K +SS DC
Sbjct: 1289 ESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 229 ---KYKFESCSKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAV 285
+Y+ E SK + + + S + + E+ I + E E K L QA
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQ--WRTKYETDAIQRTEELEEAKKKLAQRLQAA 1406
Query: 286 G------GVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIE----DFRQGS 335
+T+ L ++ L+ T + + +Q+ + +++Q
Sbjct: 1407 EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466
Query: 336 ETPMQVLTGSSRQSYSPGYQDF---SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERI 392
E L S +++ S G + F + +E L E L R+ + + +Q+I+ L E+I
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNL----QQEISDLTEQI 1522
Query: 393 RDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTE 452
+ R + Q + E LQ E S + E K+ +
Sbjct: 1523 AEGGKRIH-----------ELEKIKKQVEQEKCELQAALEEAEASLEHE---EGKILRIQ 1568
Query: 453 KEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLE 512
E+ Q+ + ++++ E+ +++++ + R + S++ E + R + +E
Sbjct: 1569 LELNQVKSEVDRKIA---EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1625
Query: 513 KYLADLPTLDDVQSQSLQLQILEEKN-KNLQEALIDTEKKLEEIKKQCQDKETQLICQKK 571
DL ++ + + ++ +N +N Q L DT+ L++ + +D + QL ++
Sbjct: 1626 ---GDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 572 KEKELVTTVQSLQQKVERCLEDG--IRLPMLDAKQ----LQNENDNLRQQNETASKIIDS 625
+ L ++ L+ +E+ +LDA + L +N +L + I
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 626 QQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSL 685
Q E++ ++ E ++ + K K M EEL KKE++ + + +N QT + L
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNMEQTVKDLQL 1801
Query: 686 -LDQGQE 691
LD+ ++
Sbjct: 1802 RLDEAEQ 1808
Score = 54.3 bits (129), Expect = 4e-07
Identities = 57/303 (18%), Positives = 134/303 (44%), Gaps = 32/303 (10%)
Query: 432 SEESVS--HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE---KLKTRDRY 486
++ES+ +++ + ++KL E E+ L ++ +L + +KK++E +++ +
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 487 ISSLKKKCQKESEQNKEKQRRIETLEKYLADL--PTLDDVQSQSLQLQILEEKNKNLQEA 544
I + + K +Q + R +E + + L + T ++ + ++ ++L+EA
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 545 LIDTEKKLEEIKKQCQDKETQL---------ICQK--KKEKELVTTVQSLQQKVERCLED 593
+ E ++K+ D +L + QK K++ E+ + L VE +
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247
Query: 594 GIRLPMLDAKQLQNENDNLRQQNETASKIID----------SQQDEIDRMILEIQSMQGK 643
L + + L+++ L+ + E ++I+ ++ E R + E +++ +
Sbjct: 1248 KGNLEKM-CRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 644 LSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ---QTV 700
LS+ K + +EEL+++ + AL + + C LL + E +Q + Q
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRA 1366
Query: 701 LSK 703
LSK
Sbjct: 1367 LSK 1369
Score = 32.0 bits (71), Expect = 2.3
Identities = 48/260 (18%), Positives = 98/260 (37%), Gaps = 62/260 (23%)
Query: 387 HLHERIRDNE-LRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVS-------- 437
HL + +R E L+ Q AM+ N + + L+ E T +E+ +
Sbjct: 1662 HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL 1721
Query: 438 -HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQK 496
H+Q E ++ Q+ ++ L +E + EEK K + + ++ +K
Sbjct: 1722 LHTQNTSLINTKKKLETDISQMQGEMEDIL----QEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 497 ESEQNKEKQRRIETLEKYLADLPT-LDDVQSQSL-----QLQILE--------------- 535
E + + +R + +E+ + DL LD+ + +L Q+Q LE
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 536 ------------------------EKNKN---LQEALIDTEKKLEEIKKQCQDKETQLIC 568
E KN LQ+ + + K++ K+Q ++ E Q
Sbjct: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
Query: 569 QKKKEKELVTTVQSLQQKVE 588
K ++L ++ +++ +
Sbjct: 1898 NLAKFRKLQHELEEAEERAD 1917
Score = 30.4 bits (67), Expect = 6.8
Identities = 52/267 (19%), Positives = 109/267 (40%), Gaps = 24/267 (8%)
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLL----RQKEIVIDR 380
Q +IE+ R E T SR+ D S+ +L + L ++ E I +
Sbjct: 1688 QAEIEELRATLEQ-----TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 381 QKQQITHLHERIRDNELRAQHA-----MLGHYVNCEDSYVASLQPQYENTSLQTPFSEES 435
+ ++ + + R+ E +A+ A M+ + E A L+ +N +
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802
Query: 436 VSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQ 495
+ ++Q L +K++ +L +++ E+K+ E +K ++ +K+
Sbjct: 1803 LDEAEQ----LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 496 KESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEI 555
+ E K R + ++K A V+S Q + EE++ + +LEE
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAK------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA 1912
Query: 556 KKQCQDKETQLICQKKKEKELVTTVQS 582
+++ E+Q+ + K +E+ T V S
Sbjct: 1913 EERADIAESQVNKLRVKSREVHTKVIS 1939
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 75.1 bits (183), Expect = 2e-13
Identities = 104/455 (22%), Positives = 198/455 (43%), Gaps = 71/455 (15%)
Query: 359 KWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIR---DNELRAQHAMLGHYVNCEDSYV 415
++ L KE L+ Q + R KQ T E ++ + E++A++A L H +
Sbjct: 1292 EFSRQLDEKEALVSQ----LSRGKQAFTQQIEELKRQLEEEIKAKNA-LAHALQSSRHDC 1346
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSE 471
L+ QYE EE S + E ++ L+ EV Q + QR E
Sbjct: 1347 DLLREQYE---------EEQES---KAELQRALSKANTEVAQWRTKYETDAIQRTEELEE 1394
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
KKKL ++L+ + ++ ++ KC + + Q +E L + DV+ +
Sbjct: 1395 AKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDL---------MLDVERTNAAC 1445
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
L++K +N +K L E K++C++ +L +K+ + L T + ++ E L
Sbjct: 1446 AALDKKQRNF-------DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 592 EDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTT 651
+ + L+ EN NL+Q+ + Q E + I E++ ++ ++ +EK
Sbjct: 1499 D--------QLETLKRENKNLQQEISD----LTEQIAEGGKRIHELEKIKKQVEQEKCEL 1546
Query: 652 QKMMEE----LEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ---QTVLSKR 704
Q +EE LE +E + R+ L NQ +++ + ++ +E DQ ++ + V S +
Sbjct: 1547 QAALEEAEASLEHEEGKILRIQLEL--NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 705 PLFDLTVID-----QLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEE 759
D + +L K+M L +++ + N+ A N GI +
Sbjct: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK-DTQIHL 1663
Query: 760 TENDHSTETLTKKLSDVCQ----LRRDIDELRTTI 790
+ S E L ++L+ V + L+ +I+ELR T+
Sbjct: 1664 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698
Score = 64.7 bits (156), Expect = 3e-10
Identities = 77/349 (22%), Positives = 151/349 (43%), Gaps = 51/349 (14%)
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
EK++L+EKLK ++ IS+L+ K + E + Q++I+ L+ + +L ++++++
Sbjct: 1078 EKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELE--EEIEAERASR 1135
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
E++ +L L + ++LEE Q+ KK+E E QK+ R L
Sbjct: 1136 AKAEKQRSDLSRELEEISERLEEAGGA---TSAQIEMNKKREAEF--------QKMRRDL 1184
Query: 592 EDG----------IRLPMLDA-KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSM 640
E+ +R D+ +L + DNL++ + K + EID + ++++
Sbjct: 1185 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETV 1244
Query: 641 ---QGKLSKEKLTTQKMMEELEKKERNVQRLTKALL-----------ENQRQTDETCSLL 686
+G L K T + + EL+ KE QRL L E RQ DE +L+
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV 1304
Query: 687 DQGQEPDQSRQQTV--LSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNL 744
Q Q+ Q + L ++ ++ + L + D C +L ++ + ++ +
Sbjct: 1305 SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD----CDLLREQYEEEQESK 1360
Query: 745 SLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDR 793
+ L A N + TK +D Q +++E + ++ R
Sbjct: 1361 AELQ-------RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402
Score = 62.0 bits (149), Expect = 2e-09
Identities = 103/484 (21%), Positives = 200/484 (41%), Gaps = 68/484 (14%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQ---HAMLGHYVNCEDSYVAS 417
E KIK+ L + + + +++ +T L E+ D +L+ Q + C+
Sbjct: 860 EEFQKIKDELAKSEAKRKELEEKMVTLLKEK-NDLQLQVQAEAEGLADAEERCDQLIKTK 918
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 477
+Q + + + +E +++ ++KL E+ + + L+ L+ +EK E
Sbjct: 919 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 978
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEK 537
K+K ++ L + K +++ K Q A TLDD+Q++ ++ L +
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKEKKALQE---------AHQQTLDDLQAEEDKVNTLTKA 1029
Query: 538 NKNLQEALIDTEKKLEEIKKQCQD-----------------------KETQLICQKKKEK 574
L++ + D E LE+ KK D E Q + +K K+K
Sbjct: 1030 KIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKK 1089
Query: 575 ELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQ--QNETASKI-IDSQQDEID 631
E + +LQ K+E GI+L K+LQ + L + + E AS+ + Q+ ++
Sbjct: 1090 EF--EISNLQSKIEDEQALGIQL-QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 632 RMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETC-------- 683
R E++ + +L + T +E +K+E Q++ + L E Q + T
Sbjct: 1147 R---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1203
Query: 684 -SLLDQGQEPDQ-SRQQTVLSKRPLFDLTVIDQL---FKEMSCCLFDLKALCSILNQR-- 736
S+ + G++ D R + L K ID L + +S +L+ +C L +
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 737 -AQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRR-------DIDELRT 788
+ KE L+ + +TE+ + L +K + V QL R I+EL+
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKR 1323
Query: 789 TISD 792
+ +
Sbjct: 1324 QLEE 1327
Score = 57.4 bits (137), Expect = 5e-08
Identities = 79/355 (22%), Positives = 158/355 (44%), Gaps = 31/355 (8%)
Query: 447 KLASTEKEVLQLNEF---LKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKE 503
K A TEKE+ + E +K L+ ++K+LEEK+ T + + L+ + Q E+E +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 504 KQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKE 563
+ R + L K L ++ + + + EE N L E + E+KK D E
Sbjct: 907 AEERCDQLIKTKIQLEA--KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 564 TQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKII 623
L K EKE T + KV+ E+ L AK L E L++ ++ +
Sbjct: 965 LTL---AKVEKEKHAT----ENKVKNLTEEMAGLDETIAK-LTKEKKALQEAHQQTLDDL 1016
Query: 624 DSQQDEID-------RMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQ 676
+++D+++ ++ ++ ++G L +EK K+ +LE+ +R ++ K E+
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK----KLRMDLERAKRKLEGDLKLAQESI 1072
Query: 677 RQTDETCSLLDQ---GQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDL-KALCSI 732
+ LD+ +E + S Q+ + + + + KE+ + +L + + +
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQ-LQKKIKELQARIEELEEEIEAE 1131
Query: 733 LNQRAQGKEPNLSLLLGIRSMNCSAEETENDHST--ETLTKKLSDVCQLRRDIDE 785
RA+ ++ L + ++ EE S E K+ ++ ++RRD++E
Sbjct: 1132 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1186
Score = 56.6 bits (135), Expect = 9e-08
Identities = 108/547 (19%), Positives = 221/547 (40%), Gaps = 60/547 (10%)
Query: 178 ESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKK-------RSSTLDC-- 228
ES ++ + +AL SQL + E+ R ++EI K +SS DC
Sbjct: 1289 ESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 229 ---KYKFESCSKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAV 285
+Y+ E SK + + + S + + E+ I + E E K L QA
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQ--WRTKYETDAIQRTEELEEAKKKLAQRLQAA 1406
Query: 286 G------GVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIE----DFRQGS 335
+T+ L ++ L+ T + + +Q+ + +++Q
Sbjct: 1407 EEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKC 1466
Query: 336 ETPMQVLTGSSRQSYSPGYQDF---SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERI 392
E L S +++ S G + F + +E L E L R+ + + +Q+I+ L E+I
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNL----QQEISDLTEQI 1522
Query: 393 RDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTE 452
+ R + Q + E LQ E S + E K+ +
Sbjct: 1523 AEGGKRIH-----------ELEKIKKQVEQEKCELQAALEEAEASLEHE---EGKILRIQ 1568
Query: 453 KEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLE 512
E+ Q+ + ++++ E+ +++++ + R + S++ E + R + +E
Sbjct: 1569 LELNQVKSEVDRKIA---EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKME 1625
Query: 513 KYLADLPTLDDVQSQSLQLQILEEKN-KNLQEALIDTEKKLEEIKKQCQDKETQLICQKK 571
DL ++ + + ++ +N +N Q L DT+ L++ + +D + QL ++
Sbjct: 1626 ---GDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 572 KEKELVTTVQSLQQKVERCLEDG--IRLPMLDAKQ----LQNENDNLRQQNETASKIIDS 625
+ L ++ L+ +E+ +LDA + L +N +L + I
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 626 QQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSL 685
Q E++ ++ E ++ + K K M EEL KKE++ + + +N QT + L
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNMEQTVKDLQL 1801
Query: 686 -LDQGQE 691
LD+ ++
Sbjct: 1802 RLDEAEQ 1808
Score = 54.3 bits (129), Expect = 4e-07
Identities = 57/303 (18%), Positives = 134/303 (44%), Gaps = 32/303 (10%)
Query: 432 SEESVS--HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE---KLKTRDRY 486
++ES+ +++ + ++KL E E+ L ++ +L + +KK++E +++ +
Sbjct: 1068 AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 487 ISSLKKKCQKESEQNKEKQRRIETLEKYLADL--PTLDDVQSQSLQLQILEEKNKNLQEA 544
I + + K +Q + R +E + + L + T ++ + ++ ++L+EA
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 545 LIDTEKKLEEIKKQCQDKETQL---------ICQK--KKEKELVTTVQSLQQKVERCLED 593
+ E ++K+ D +L + QK K++ E+ + L VE +
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKA 1247
Query: 594 GIRLPMLDAKQLQNENDNLRQQNETASKIID----------SQQDEIDRMILEIQSMQGK 643
L + + L+++ L+ + E ++I+ ++ E R + E +++ +
Sbjct: 1248 KGNLEKM-CRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 644 LSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ---QTV 700
LS+ K + +EEL+++ + AL + + C LL + E +Q + Q
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRA 1366
Query: 701 LSK 703
LSK
Sbjct: 1367 LSK 1369
Score = 32.0 bits (71), Expect = 2.3
Identities = 48/260 (18%), Positives = 98/260 (37%), Gaps = 62/260 (23%)
Query: 387 HLHERIRDNE-LRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVS-------- 437
HL + +R E L+ Q AM+ N + + L+ E T +E+ +
Sbjct: 1662 HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL 1721
Query: 438 -HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQK 496
H+Q E ++ Q+ ++ L +E + EEK K + + ++ +K
Sbjct: 1722 LHTQNTSLINTKKKLETDISQMQGEMEDIL----QEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 497 ESEQNKEKQRRIETLEKYLADLPT-LDDVQSQSL-----QLQILE--------------- 535
E + + +R + +E+ + DL LD+ + +L Q+Q LE
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 536 ------------------------EKNKN---LQEALIDTEKKLEEIKKQCQDKETQLIC 568
E KN LQ+ + + K++ K+Q ++ E Q
Sbjct: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNT 1897
Query: 569 QKKKEKELVTTVQSLQQKVE 588
K ++L ++ +++ +
Sbjct: 1898 NLAKFRKLQHELEEAEERAD 1917
Score = 30.4 bits (67), Expect = 6.8
Identities = 52/267 (19%), Positives = 109/267 (40%), Gaps = 24/267 (8%)
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLL----RQKEIVIDR 380
Q +IE+ R E T SR+ D S+ +L + L ++ E I +
Sbjct: 1688 QAEIEELRATLEQ-----TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 381 QKQQITHLHERIRDNELRAQHA-----MLGHYVNCEDSYVASLQPQYENTSLQTPFSEES 435
+ ++ + + R+ E +A+ A M+ + E A L+ +N +
Sbjct: 1743 MQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1802
Query: 436 VSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQ 495
+ ++Q L +K++ +L +++ E+K+ E +K ++ +K+
Sbjct: 1803 LDEAEQ----LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858
Query: 496 KESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEI 555
+ E K R + ++K A V+S Q + EE++ + +LEE
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAK------VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEA 1912
Query: 556 KKQCQDKETQLICQKKKEKELVTTVQS 582
+++ E+Q+ + K +E+ T V S
Sbjct: 1913 EERADIAESQVNKLRVKSREVHTKVIS 1939
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 73.6 bits (179), Expect = 7e-13
Identities = 93/395 (23%), Positives = 177/395 (44%), Gaps = 57/395 (14%)
Query: 415 VASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK 474
+A+ Q Y++T + F H +FEQK K VL+ NE + Q + S+E +
Sbjct: 805 LATTQSNYKSTDQE--FQNFKTLHM---DFEQKY----KMVLEENERMNQEIVNLSKEAQ 855
Query: 475 KLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQIL 534
K + L + L K Q+ E+ +E Q R+ +E+ L D LQ +
Sbjct: 856 KFDSSLGALK---TELSYKTQELQEKTREVQERLNEMEQLKEQLENRDST------LQTV 906
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
E + + E L T LEE+K Q+K+ K+L ++Q + +++ + D
Sbjct: 907 EREKTLITEKLQQT---LEEVKTLTQEKDDL--------KQLQESLQIERDQLKSDIHDT 955
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKM 654
+ + + +QL+N ++L+Q ET + + +E+ R + M+ + K Q+
Sbjct: 956 VNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNL----HMEENTGETKDEFQQK 1011
Query: 655 MEELEKKE----RNVQRLTKALLENQ--RQTDETCSLLDQGQEPDQSRQQTVLSKRPL-- 706
M ++KK+ +N Q LT + +N+ Q + SL+ + E Q + + K L
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1071
Query: 707 -----FDLTVIDQLFKEMSCCLFDLKALCSILNQ---RAQGKEPNLSLLLGIRSMNCSAE 758
++T+ +Q +E+ +LK I+ Q A KE LS R+ + AE
Sbjct: 1072 DLKENIEMTIENQ--EELRLLGDELKKQQEIVAQEKNHAIKKEGELS-----RTCDRLAE 1124
Query: 759 -ETENDHSTETLTKKLSDVCQLRRDIDELRTTISD 792
E + ++ L +K + ++ ++ E++ I++
Sbjct: 1125 VEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINE 1159
Score = 70.9 bits (172), Expect = 5e-12
Identities = 96/448 (21%), Positives = 179/448 (39%), Gaps = 58/448 (12%)
Query: 262 SKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRNTE-DSYSL 320
+K I+ + + +Y L AV Q + L EQ T L N E ++ L
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNET--QEKMCEIEHLKEQFETQKLNLENIETENIRL 1670
Query: 321 APWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQ---KEIV 377
+ +E+ R S + D E LK++ L++ + I
Sbjct: 1671 TQILHENLEEMR----------------SVTKERDDLRSVEETLKVERDQLKENLRETIT 1714
Query: 378 IDRQKQQ---ITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEE 434
D +KQ+ I H+H + + ++ N + L+ + Q +E
Sbjct: 1715 RDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE 1774
Query: 435 S--VSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEK---LKTRDRYISS 489
++H E ++ + V + + L KL+EK LK + + +
Sbjct: 1775 ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLIT 1834
Query: 490 LKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTE 549
LKK + + ++K +E L+K + D QSL L LE +N NL + L
Sbjct: 1835 LKK----DVNETQKKVSEMEQLKKQIKD---------QSLTLSKLEIENLNLAQKL---H 1878
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNEN 609
+ LEE+K ++++ ++ + E +SLQ+ R LE +Q E
Sbjct: 1879 ENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE------------IQQEL 1926
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLT 669
R ++ + +D +++I ++I +Q L K K QK ++EL+KKE + R+
Sbjct: 1927 KTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVK 1986
Query: 670 KALLENQRQTDETCSLLDQGQEPDQSRQ 697
+ + + ++ +E L Q + + S Q
Sbjct: 1987 EDVNMSHKKINEMEQLKKQFEAQNLSMQ 2014
Score = 62.0 bits (149), Expect = 2e-09
Identities = 124/659 (18%), Positives = 267/659 (40%), Gaps = 109/659 (16%)
Query: 174 VCREESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFE 233
+ +E + ++K G+ +L + E L+ + +++ +K+ L+ + +
Sbjct: 1100 IVAQEKNHAIKKEGELSRTCDRLAEVE--------EKLKEKSQQLQEKQQQLLNVQEEMS 1151
Query: 234 SCSKE--DFRASSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQ 291
K+ + + L+ + + + + + +E +E K + ++ + +Q
Sbjct: 1152 EMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLK--ELQ 1209
Query: 292 PSVRTQM-WLTEQLRTNPLEGRNTEDSYSLA----PWQQQQIEDFRQG-SETPMQVLTGS 345
S T+ L +R G T++ +A Q+ I++ R+ SE Q++
Sbjct: 1210 KSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT- 1268
Query: 346 SRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLG 405
QD K + L+ + +L +++ ++ K+ ++ E + + EL + +
Sbjct: 1269 ---------QDLEKSHTKLQEEIPVLHEEQELLPNVKE-VSETQETMNELELLTEQS--- 1315
Query: 406 HYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVL-----QLNE 460
+DS + + + E L F +ES + E+ T KE L QL E
Sbjct: 1316 ---TTKDSTTLA-RIEMERLRLNEKF-QESQEEIKSLTKERDNLKTIKEALEVKHDQLKE 1370
Query: 461 FLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKE-------------------SEQN 501
+++ L+ E + K E+ L +++ + K + E S++
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRL 1430
Query: 502 KEKQRRIETLEKYLADLPTLDDV-QSQSLQLQI-----------LEEKNKNLQEALIDTE 549
+E ++++ K DL L +V QS+S QL+ EE+ K L + E
Sbjct: 1431 QESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNEN 609
+ + E++ +KET++ +K+L LQ K++ E + + ++Q +
Sbjct: 1491 ETINELRVNLSEKETEI---STIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKV 1547
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLT 669
+ L+Q E K DS I+ +LE+ + + +E K EE+++ + +Q
Sbjct: 1548 NELKQFKEHR-KAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIER 1606
Query: 670 KALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKAL 729
L EN T E + + + QE + +T +++ ++M
Sbjct: 1607 DQLKEN---TKEIVAKMKESQEKEYQ----------FLKMTAVNETQEKM---------- 1643
Query: 730 CSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRT 788
C I + + Q + L+L ETEN T+ L + L ++ + ++ D+LR+
Sbjct: 1644 CEIEHLKEQFETQKLNL---------ENIETENIRLTQILHENLEEMRSVTKERDDLRS 1693
Score = 60.5 bits (145), Expect = 6e-09
Identities = 92/418 (22%), Positives = 184/418 (44%), Gaps = 51/418 (12%)
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLAST----EKEVLQLNEFLKQRLS 467
+S + SL+ Y+N L + +++ E E KL E E L+ Q +
Sbjct: 497 ESELNSLRADYDNLVL-----DYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQ 551
Query: 468 LFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQ 527
L E L+ +K + Y L+ + + E +EK+ +I+ L++Y+ D L++++
Sbjct: 552 LI-HEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYI-DSQKLENIKMD 609
Query: 528 -SLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQK 586
S L+ +E+ K +++ L D E + K++ ++ + K+K KEL TT + ++
Sbjct: 610 LSYSLESIEDP-KQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMEND 668
Query: 587 VERCLEDGIRLPMLDAKQ-----LQNENDNLRQQNETASKIIDSQ--QDEIDRMILE--I 637
++ + L+AK+ L+ E + + + +ID + +D + + LE I
Sbjct: 669 IQ------LYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKI 722
Query: 638 QSMQGKLSKEKLTTQKMME------ELEKKERNVQRLTKALLENQRQ----TDETCSLLD 687
+Q +L+KE + + E EL+ V+RL K + + + T E L
Sbjct: 723 TDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFS 782
Query: 688 QGQEPDQSRQQTVLSK--RPLFDLTV-------IDQLFKEMSCCLFDLKALCSIL---NQ 735
+ +SR Q +L + + DL DQ F+ D + ++ N+
Sbjct: 783 EVVH-KESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENE 841
Query: 736 RAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDR 793
R + NLS + A +TE + T+ L +K +V + ++++L+ + +R
Sbjct: 842 RMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENR 899
Score = 58.9 bits (141), Expect = 2e-08
Identities = 91/434 (20%), Positives = 179/434 (41%), Gaps = 63/434 (14%)
Query: 384 QITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEE-----SVSH 438
+I HL E+ +L + N E + Q +EN ++E SV
Sbjct: 1645 EIEHLKEQFETQKLNLE--------NIETENIRLTQILHENLEEMRSVTKERDDLRSVEE 1696
Query: 439 S---QQGEFEQKLASTEKEVLQLNEFLK---QRLSLFSEEKKKLEEKLKTRDRYISSLKK 492
+ ++ + ++ L T L+ E LK L E KL + + IS+++K
Sbjct: 1697 TLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQK 1756
Query: 493 KCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN---KNLQEALIDTE 549
+ ++ K + +I+ E +A + + ++ I+ EK N+Q+ L ++
Sbjct: 1757 DLEHSNDALKAQDLKIQE-ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSN 1815
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDA------- 602
KL+E ++ + E QLI KK E V ++Q ++ + + L L+
Sbjct: 1816 AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQ 1875
Query: 603 ---------KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQK 653
K + E DNLR+ ET + ++D++ + E ++ ++ +E L T +
Sbjct: 1876 KLHENLEEMKSVMKERDNLRRVEET----LKLERDQLKESLQETKARDLEIQQE-LKTAR 1930
Query: 654 MMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVID 713
M+ + K+ V +L + + E Q + LD+ ++ Q + Q L K+ L
Sbjct: 1931 MLSKEHKE--TVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQE-LQKKEL------- 1980
Query: 714 QLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKL 773
QL + K + + + Q + NLS+ + +N T+ L + L
Sbjct: 1981 QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSM---------QSVRMDNFQLTKKLHESL 2031
Query: 774 SDVCQLRRDIDELR 787
++ + ++ DELR
Sbjct: 2032 EEIRIVAKERDELR 2045
Score = 57.8 bits (138), Expect = 4e-08
Identities = 68/290 (23%), Positives = 125/290 (43%), Gaps = 41/290 (14%)
Query: 440 QQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE---EKLKTRDRYISSLKKKC-Q 495
++ E +Q L S E QL LK+ + + E +++L ++LK + ++ K +
Sbjct: 1051 EKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK 1110
Query: 496 KESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEI 555
KE E ++ R E EK ++ +S QLQ +++ N+QE + + +KK+ EI
Sbjct: 1111 KEGELSRTCDRLAEVEEK----------LKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI 1160
Query: 556 ---KKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNL 612
K + ++KE L + + EL + ++V+ ++ L L K + E D+L
Sbjct: 1161 ENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ-KSFETERDHL 1219
Query: 613 R----------QQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKE 662
R Q + KI E I E++ + + + + TQ +LEK
Sbjct: 1220 RGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQ----DLEKSH 1275
Query: 663 RNVQRLTKALLENQR---------QTDETCSLLDQGQEPDQSRQQTVLSK 703
+Q L E Q +T ET + L+ E ++ T L++
Sbjct: 1276 TKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLAR 1325
Score = 54.7 bits (130), Expect = 3e-07
Identities = 85/464 (18%), Positives = 187/464 (40%), Gaps = 55/464 (11%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRD-----NELRAQHAMLGHYVNCEDSYV 415
E LK K L++K+ + +++++ + ++I + NEL+ + L H
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA 1185
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQ--LNEFLKQRLSLFSEEK 473
L YE T E V Q FE TE++ L+ + E L EE
Sbjct: 1186 QKLNENYEEVKSIT--KERKVLKELQKSFE-----TERDHLRGYIREIEATGLQT-KEEL 1237
Query: 474 KKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQI 533
K LK I L++ +++ Q Q ++ K ++P L + Q ++
Sbjct: 1238 KIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKE 1297
Query: 534 LEEKNKNLQEALIDTEKKLEE--------------IKKQCQDKETQLICQKKKEKELVTT 579
+ E + + E + TE+ + + ++ Q+ + ++ K+ L T
Sbjct: 1298 VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 580 VQSLQQKVERCLEDGIRLPMLDAKQLQNEND---NLRQQNETASKIIDSQQD--EIDRMI 634
++L+ K ++ L++ IR + ++ Q++ + N+++++ +KI+ + D +
Sbjct: 1358 KEALEVKHDQ-LKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSAL 1416
Query: 635 LEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQ 694
L I+ LSK + M+ + K++ ++QRL + L Q E
Sbjct: 1417 LRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI----------- 1465
Query: 695 SRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLL-LGIRSM 753
+ +++K ++ K CCL + + + L KE +S + + ++
Sbjct: 1466 ---KEIVAKH-----LETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAI 1517
Query: 754 NCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDRYAQD 797
N + + + + + +++ ++EL+ R A+D
Sbjct: 1518 NDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKD 1561
Score = 51.2 bits (121), Expect = 4e-06
Identities = 73/357 (20%), Positives = 138/357 (38%), Gaps = 65/357 (18%)
Query: 372 RQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPF 431
+QKE++I +I HL + + L ++ + + E S++T F
Sbjct: 2204 KQKELLI-----KIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEF 2258
Query: 432 SEESVSHSQQGEFEQKLAST-----------EKE---VLQLNEFLKQRLSLFSEEKKKLE 477
+ + + +F ++ +T +KE + Q+N F R+ E + E
Sbjct: 2259 QQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFE 2318
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRI----ETLEKYLADLPTLDDVQSQSLQLQI 533
E+ T + K+ +++ + KEK ++ +TL+ LA ++ + +
Sbjct: 2319 ERSAT-------ISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHV 2371
Query: 534 LEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTT---VQSLQQKVERC 590
+ E + + E L E K+ KE+++I K +KEL T + LQ KV
Sbjct: 2372 TSRATQLTTEKIRELENSLHEAKESAMHKESKII---KMQKELEVTNDIIAKLQAKV--- 2425
Query: 591 LEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLT 650
N L + ET + D EI+ ++ KL K L
Sbjct: 2426 ---------------HESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLE 2470
Query: 651 TQKMMEELEKK----------ERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
K +E EK+ ++ V RL + L +Q +T S++ + +P S +
Sbjct: 2471 KMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDT-SVISEHTDPQPSNK 2526
Score = 47.0 bits (110), Expect = 7e-05
Identities = 80/358 (22%), Positives = 141/358 (39%), Gaps = 48/358 (13%)
Query: 356 DFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNE-----LRAQHAMLGHYVNC 410
D SK E KI+E L++KE+ + R K+ + H++I + E AQ+ +
Sbjct: 1962 DKSKDELQKKIQE--LQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMD 2019
Query: 411 EDSYVASLQPQYENTSLQTPFSEE--SVSHSQQGEFEQKLASTEKEVLQ--LNEFLKQRL 466
L E + +E + S + E +Q +A+ + + + N +K
Sbjct: 2020 NFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEK 2079
Query: 467 SLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQS 526
L S+ ++ L E L+ + I L K+ + + + R LEK + L
Sbjct: 2080 RLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVK 2139
Query: 527 QSLQLQILEEKN-------------------KNLQEALIDTEKKLEEIKKQCQDKETQLI 567
+L L L+ K+ K L+ L K EE + E I
Sbjct: 2140 ANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFI 2199
Query: 568 CQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQ 627
+ +K+KEL+ +Q LQQ + +P + + L+ N N+ E K D +
Sbjct: 2200 DEVEKQKELLIKIQHLQQDCD--------VPSRELRDLK-LNQNMDLHIEEILK--DFSE 2248
Query: 628 DEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSL 685
E + E Q + LS K TQ +EE ++++L + Q++ D C +
Sbjct: 2249 SEFPSIKTEFQQV---LSNRKEMTQ-FLEEWLNTRFDIEKLKNGI---QKENDRICQV 2299
Score = 33.5 bits (75), Expect = 0.81
Identities = 47/221 (21%), Positives = 94/221 (42%), Gaps = 16/221 (7%)
Query: 477 EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQ---LQI 533
E LK + I LKK+ ++ S + + + + L + L + L VQ++ ++ +
Sbjct: 342 EALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRML 401
Query: 534 LEEKNKNLQEALIDTEKK-----LEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE 588
+ + LQ+ L K+ L +I K K + Q + T L +
Sbjct: 402 VTSSSLTLQQELKAKRKRRVTWCLGKINKM---KNSNYADQFNIPTNITTKTHKLSINLL 458
Query: 589 RCLEDGIRLPMLDAKQLQNENDNLRQ-QNETASKIIDSQQDEIDRMILEIQSMQGKLSKE 647
R +++ + ++ N D L + + A+K+++ + E + L L E
Sbjct: 459 REIDESV---CSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYE 515
Query: 648 KLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQ 688
+L T+K EL+ KE+N +A LE + + D+ L+ +
Sbjct: 516 QLRTEKEEMELKLKEKNDLDEFEA-LERKTKKDQEMQLIHE 555
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 73.2 bits (178), Expect = 9e-13
Identities = 78/371 (21%), Positives = 171/371 (46%), Gaps = 38/371 (10%)
Query: 303 QLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWES 362
QL L+ R E + L P QQ Q E G E S ++ W
Sbjct: 229 QLNVKELK-RKLERAKLLLPQQQLQAEADHLGKELQ------SVSAKLQAQVEENELWNR 281
Query: 363 MLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVASLQP 420
+ + +E + ++E I ++++I E+IR+ E +R Q M+ E+ +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK---EEKMRRQEEM 338
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK--KLEE 478
+E EE + ++ EQ+ ++E Q E ++++ +E K + EE
Sbjct: 339 MWEK--------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 390
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
K++ ++ I ++ Q++ E+ E++ ++ E +++Q Q +++ EEK
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE---------EEMQEQEEKMRRQEEKI 441
Query: 539 KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLP 598
+ ++ + + E+K+ E ++ Q++E ++ Q+ K E +Q ++K+ R E+ IR
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR-QEEKIR-- 498
Query: 599 MLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEE- 657
K+++ + + +R+Q E + + ++ ++M + + MQ + K + +KM E+
Sbjct: 499 -EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Query: 658 --LEKKERNVQ 666
L ++E +Q
Sbjct: 558 VRLRQQEEKMQ 568
Score = 67.4 bits (163), Expect = 5e-11
Identities = 75/359 (20%), Positives = 174/359 (48%), Gaps = 39/359 (10%)
Query: 358 SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVAS 417
+K + L++ E + ++ + K+++ + +L+A+ LG + S A
Sbjct: 212 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAK 268
Query: 418 LQPQYENTSLQTPFS---EESVSHSQQG--EFEQKLASTEKEVLQLNEFLKQRLSLFSEE 472
LQ Q E L + EE + ++ E E+K+ E+++ + E ++++ + E+
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK 328
Query: 473 KKKL---EEKLKTRDRYISSLKKKC--------QKESEQNKEKQRRIETLEKYLADLPTL 521
++K+ EE + ++ I L++K Q+E Q +EK R E ++ A +
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 522 DD--------VQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKK- 572
++ ++ Q +Q EEK +E + + E++++E +++ + +E ++ Q+KK
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 573 ---EKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETA---SKIIDSQ 626
E+++ + +Q++ E+ E ++ +AK +Q + + +R+Q E K I Q
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK-MQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 627 QDEIDRMILEIQSMQGKL--SKEKLTTQ--KMMEELEKKERNVQRLTKALLENQRQTDE 681
+++I +Q + K+ +EK+ Q KM E+ EK R +++ + + ++Q ++
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 63.2 bits (152), Expect = 1e-09
Identities = 64/349 (18%), Positives = 160/349 (45%), Gaps = 40/349 (11%)
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSY-------VASLQPQYENTS 426
+E+ +R + I D EL+ ++A L + +S V L+ + E
Sbjct: 184 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 243
Query: 427 LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRY 486
L P + G+ Q +++ + ++ NE L++ ++ EEK+ ++
Sbjct: 244 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE-------LWNRLNQQQEEKMWRQEEK 296
Query: 487 ISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALI 546
I ++K Q++ E+ +E++ ++ E+ + + + ++ Q + EEK + L+E +
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 547 DTEKKLEEIKK-----------QCQDKETQLICQKKK---EKELVTTVQSLQQKVERCLE 592
+ EK E+ +K + Q++E ++ Q++K ++E + + + Q+ E +
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 593 DGIRLPMLDAKQLQNENDNLRQQNE---TASKIIDSQQDEI---DRMILE----IQSMQG 642
+ +++Q + + +R+Q E K I Q+++I + M+ E + +G
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 643 KLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQE 691
K+ +++ Q+ E++ ++E ++ K + E + + E ++ + +E
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
Score = 55.5 bits (132), Expect = 2e-07
Identities = 73/387 (18%), Positives = 167/387 (43%), Gaps = 29/387 (7%)
Query: 207 SMEMLR--LEDKEINKKRSSTLDCKYKFESCSKEDFRASSSTLRRQPVDMTYSALPESKP 264
S+E+ R + D+E+ K++++ L K + K + + + L+R+ L +K
Sbjct: 194 SLELYRNTITDEEL-KEKNAKLQEKLQLVESEKSEIQLNVKELKRK--------LERAKL 244
Query: 265 IMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQ 324
++ + +L Q+V ++W + R E
Sbjct: 245 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKI 304
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQ 384
Q+Q E R+ E + + Q+ WE KI+E + E R++++
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Query: 385 ITHLHERIRDNELRA-QHAMLGHY---VNCEDSYVAS----LQPQYENTSLQTPFSEESV 436
E+IR+ E R Q A + + ++ + +Q Q E Q E
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 437 SHSQQGEF-----EQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE---KLKTRDRYIS 488
Q+ E E+K+ EK++ + E ++++ + E+++K+ E K+ ++ +
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 489 SLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDT 548
++K +++ E+ +E++++I E+ + + + Q + + Q EEK +E + +
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ--EEKMCEQEEKMQEQ 542
Query: 549 EKKLEEIKKQCQDKETQLICQKKKEKE 575
E+K+ +++ +++E +L Q++K +E
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 48.1 bits (113), Expect = 3e-05
Identities = 60/308 (19%), Positives = 132/308 (42%), Gaps = 38/308 (12%)
Query: 429 TPFSEESVSHSQQGEFEQKLAST---------EKEVLQLNEFLKQR-LSLFSEEKKKLEE 478
+P E+ SH Q ++L + +K LQ+ + Q + E + L
Sbjct: 94 SPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 153
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
+L ++ L++ + Q K+ R IE L K L ++ ++ + L+EKN
Sbjct: 154 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSL--ELYRNTITDEELKEKN 211
Query: 539 KNLQEALIDTEKKLEEIK------KQCQDKETQLICQKKKEKE---LVTTVQSLQQKVER 589
LQE L E + EI+ K+ ++ L+ Q++ + E L +QS+ K++
Sbjct: 212 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 271
Query: 590 CLEDGIRLPMLDAKQ-----------------LQNENDNLRQQNETASKIIDSQQDEIDR 632
+E+ L+ +Q +Q + + +R+Q E + + ++ ++
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 633 MILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEP 692
M + + M K K + +KM E+ + +E+ +R + + Q + E + + + +E
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 693 DQSRQQTV 700
+ +++ +
Sbjct: 392 IREQEEKI 399
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 72.8 bits (177), Expect = 1e-12
Identities = 109/505 (21%), Positives = 209/505 (41%), Gaps = 88/505 (17%)
Query: 312 RNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLL 371
R ED S A + ++I+ + ++ T SR G + L+ KE ++
Sbjct: 1251 RTLEDQLSEARGKNEEIQ------RSLSELTTQKSRLQTEAG-----ELSRQLEEKESIV 1299
Query: 372 RQKEIVIDRQKQQITHLHERIR---DNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQ 428
Q + R KQ T E ++ + E +A++A L H + L+ QYE
Sbjct: 1300 SQ----LSRSKQAFTQQTEELKRQLEEENKAKNA-LAHALQSSRHDCDLLREQYEE---- 1350
Query: 429 TPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSEEKKKLEEKLKTRD 484
+ E ++ L+ EV Q + QR E KKKL ++L+ +
Sbjct: 1351 --------EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE 1402
Query: 485 RYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEA 544
+ ++ KC + + Q +E L + DV+ + L++K +N
Sbjct: 1403 EQVEAVNAKCASLEKTKQRLQGEVEDL---------MVDVERANSLAAALDKKQRNF--- 1450
Query: 545 LIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQ 604
+K L E K +C++ + +L K+ + L T + L+ E L+ +
Sbjct: 1451 ----DKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALD--------QLET 1498
Query: 605 LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEE----LEK 660
++ EN NL Q+ + Q E + I E++ + ++ EK Q +EE LE
Sbjct: 1499 VKRENKNLEQEIAD----LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEH 1554
Query: 661 KERNVQRLTKALLENQRQTDETCSLLDQG-QEPDQSRQQTVLSKRPLFDLTVID-----Q 714
+E + R+ L + + + D + D+ ++ ++ Q+TV + + D V +
Sbjct: 1555 EEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIR 1614
Query: 715 LFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETEND-----HSTETL 769
L K+M L +++ S N++A L +RS+ ++T+ E L
Sbjct: 1615 LKKKMEGDLNEIEIQLSHANRQA------AETLKHLRSVQGQLKDTQLHLDDALRGQEDL 1668
Query: 770 TKKLSDVCQ----LRRDIDELRTTI 790
++L+ V + L+ +++ELR T+
Sbjct: 1669 KEQLAIVERRANLLQAEVEELRATL 1693
Score = 58.2 bits (139), Expect = 3e-08
Identities = 101/501 (20%), Positives = 209/501 (41%), Gaps = 66/501 (13%)
Query: 322 PWQQQ--QIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVID 379
PW + +I+ + +ET ++ T ++ + + +K E+ K KE L +K + +
Sbjct: 829 PWMKLFFKIKPLLKSAETEKEMAT--MKEEFQKTKDELAKSEA--KRKE--LEEKLVTLV 882
Query: 380 RQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHS 439
++K + + +N L A+ C+ A Q + + + +E ++
Sbjct: 883 QEKNDLQLQVQAESENLLDAEE-------RCDQLIKAKFQLEAKIKEVTERAEDEEEINA 935
Query: 440 QQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESE 499
+ ++KL E+ + + L+ L+ +EK E K+K +S L + K +
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
Query: 500 QNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQC 559
+ K Q A LDD+Q++ ++ L + L++ + D E LE+ KK
Sbjct: 996 EKKALQE---------AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLR 1046
Query: 560 QDKETQLICQKKKEKELVTTVQSL--QQKVERCLEDGIRLPMLDAKQLQN---ENDNLRQ 614
D E ++K E +L +S+ + ++ L++ ++ + QLQ+ + L
Sbjct: 1047 VDLERN---KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 1103
Query: 615 QNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEEL---------------- 658
Q + K + ++ +E++ I ++ + K K++ + +EEL
Sbjct: 1104 QFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIE 1163
Query: 659 --EKKERNVQRLTKALLENQRQTD---------ETCSLLDQGQEPD--QSRQQTVLSKRP 705
+K+E +L + L E Q + S+ + G++ D Q +Q + ++
Sbjct: 1164 LNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1223
Query: 706 LFDLTVID--QLFKEMSCCLFDLKALCSILNQR---AQGKEPNLSLLLGIRSMNCSAEET 760
F L + D + +S +L+ +C L + A+GK + L + S +T
Sbjct: 1224 EFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQT 1283
Query: 761 ENDHSTETLTKKLSDVCQLRR 781
E + L +K S V QL R
Sbjct: 1284 EAGELSRQLEEKESIVSQLSR 1304
Score = 55.5 bits (132), Expect = 2e-07
Identities = 79/371 (21%), Positives = 159/371 (42%), Gaps = 59/371 (15%)
Query: 378 IDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVS 437
+ R+K+ + H++ D+ + E+ V SL Q E S+
Sbjct: 993 LTREKKALQEAHQQALDD------------LQAEEDKVNSLNKTKSKLEQQVEDLESSLE 1040
Query: 438 HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKE 497
Q+ + L ++++ + ++ + +K++L+E+LK +D L+ K + E
Sbjct: 1041 --QEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098
Query: 498 S-------EQNKEKQRRIETLEKYL-ADLPTLDDVQSQ-SLQLQILEEKNKNLQEA---- 544
++ KE Q RIE LE+ + A+ T + Q S + LEE ++ L+EA
Sbjct: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158
Query: 545 --LIDTEKKLE--------EIKKQCQDKETQLICQKKKEK-------ELVTTVQSLQQKV 587
I+ KK E ++++ E + +KK E + +Q ++QK+
Sbjct: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
Query: 588 ERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKE 647
E+ + L+ L + +++ + KI + +D++ + + +Q LS+
Sbjct: 1219 EKEKSEF----KLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSE- 1273
Query: 648 KLTTQK---------MMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQ 698
LTTQK + +LE+KE V +L+++ +QT+E L++ + +
Sbjct: 1274 -LTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH 1332
Query: 699 TVLSKRPLFDL 709
+ S R DL
Sbjct: 1333 ALQSSRHDCDL 1343
Score = 55.5 bits (132), Expect = 2e-07
Identities = 87/382 (22%), Positives = 152/382 (39%), Gaps = 49/382 (12%)
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQ 384
+QQ+ED E ++ R K E LK L ++ + ++ KQQ
Sbjct: 1029 EQQVEDLESSLEQEKKLRVDLERNK--------RKLEGDLK----LAQESILDLENDKQQ 1076
Query: 385 ITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEF 444
L ER++ + ++ L V ED LQ Q + LQ E + E
Sbjct: 1077 ---LDERLKKKDF--EYCQLQSKV--EDEQTLGLQFQKKIKELQARIEE------LEEEI 1123
Query: 445 EQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEK 504
E + A+ K Q +++ ++ E ++LEE I KK+ E+E K +
Sbjct: 1124 EAERATRAKTEKQRSDYARE----LEELSERLEEAGGVTSTQIELNKKR---EAEFLKLR 1176
Query: 505 QRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKET 564
+ E ++ A + L + S+ L E+ NLQ EK+ E K + D +
Sbjct: 1177 RDLEEATLQHEAMVAALRKKHADSVAE--LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSS 1234
Query: 565 QLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIID 624
+ K + L +K+ R LED + +++Q L Q +
Sbjct: 1235 SMESVSKSKANL--------EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSR----LQ 1282
Query: 625 SQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCS 684
++ E+ R + E +S+ +LS+ K + EEL+++ + AL + + C
Sbjct: 1283 TEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCD 1342
Query: 685 LLDQGQEPDQ---SRQQTVLSK 703
LL + E +Q + Q LSK
Sbjct: 1343 LLREQYEEEQEGKAELQRALSK 1364
Score = 46.2 bits (108), Expect = 1e-04
Identities = 52/237 (21%), Positives = 105/237 (44%), Gaps = 23/237 (9%)
Query: 371 LRQKEIVIDRQKQQITHLHERIRDNE-LRAQHAMLGHYVNCEDSYVASLQPQYENTSLQT 429
L+ V + K HL + +R E L+ Q A++ N + V L+ E T
Sbjct: 1641 LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERAR 1700
Query: 430 PFSEESVS---------HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
+E+ + H+Q E +++QL ++ S + + EEK
Sbjct: 1701 KLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDA----SRDARNAEEKA 1756
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLP-TLDDVQSQSL-----QLQIL 534
K + + ++ +KE + + +R + LE+ + DL LD+ + +L Q+Q L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 535 EEKNKNLQEALIDTEKK-LEEIK--KQCQDKETQLICQKKKEKELVTTVQSLQQKVE 588
E + + L+ L +KK E +K ++ + + +L Q +++++ V +Q L K++
Sbjct: 1817 ETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQ 1873
Score = 44.3 bits (103), Expect = 5e-04
Identities = 59/281 (20%), Positives = 118/281 (41%), Gaps = 33/281 (11%)
Query: 443 EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESE--- 499
E E L E ++L++ L Q K +++ K+ +D I LK+ Q+ E
Sbjct: 1547 EAEAALEHEEAKILRIQLELTQ-------VKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 1599
Query: 500 -----QNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN--KNLQEALIDTEKKL 552
+ + + I +K DL ++ +Q Q E +++Q L DT+ L
Sbjct: 1600 SALDAEVRSRNEAIRLKKKMEGDLNEIE-IQLSHANRQAAETLKHLRSVQGQLKDTQLHL 1658
Query: 553 EEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLP---MLDAKQ----L 605
++ + +D + QL +++ L V+ L+ +E+ E +L +LD+ + L
Sbjct: 1659 DDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT-ERARKLAEQELLDSNERVQLL 1717
Query: 606 QNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK---- 661
+N +L + + Q E++ + ++ + K K M EEL+K+
Sbjct: 1718 HTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777
Query: 662 ---ERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQT 699
ER + L + + + Q + DE L +G + + +T
Sbjct: 1778 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 72.0 bits (175), Expect = 2e-12
Identities = 77/349 (22%), Positives = 154/349 (44%), Gaps = 50/349 (14%)
Query: 359 KWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIR---DNELRAQHAMLGHYVNCEDSYV 415
++ L K+ L+ Q + R KQ T E ++ + E++A+ A L H +
Sbjct: 1290 EYSRQLDEKDTLVSQ----LSRGKQAFTQQIEELKRQLEEEIKAKSA-LAHALQSSRHDC 1344
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKK 475
L+ QYE + ++S + E Q E + +Q E L+ E KKK
Sbjct: 1345 DLLREQYEEEQEAKAELQRAMSKANS-EVAQWRTKYETDAIQRTEELE-------EAKKK 1396
Query: 476 LEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILE 535
L ++L+ + ++ ++ KC + + Q +E L + DV+ + L+
Sbjct: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDL---------MIDVERTNAACAALD 1447
Query: 536 EKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGI 595
+K +N +K L E K++C++ +L +K+ + L T + ++ E L+
Sbjct: 1448 KKQRNF-------DKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD--- 1497
Query: 596 RLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMM 655
+ L+ EN NL+Q+ + Q E + I E++ ++ ++ +EK Q +
Sbjct: 1498 -----QLETLKRENKNLQQEISD----LTEQIAEGGKRIHELEKIKKQVEQEKSELQAAL 1548
Query: 656 EE----LEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTV 700
EE LE +E + R+ L NQ +++ + ++ +E DQ ++ +
Sbjct: 1549 EEAEASLEHEEGKILRIQLEL--NQVKSEVDRKIAEKDEEIDQMKRNHI 1595
Score = 62.8 bits (151), Expect = 1e-09
Identities = 69/315 (21%), Positives = 149/315 (47%), Gaps = 39/315 (12%)
Query: 415 VASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK 474
+A+++ ++E T E + + +++ E E+K+ + +E L ++ ++ ++
Sbjct: 853 MANMKEEFEKTK-----EELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE 907
Query: 475 KLEEKLKTR---DRYISSLKKKCQKESEQNKE---KQRRIE----TLEKYLADLP-TLDD 523
+ ++ +KT+ + I + ++ + E E N E K+R++E L+K + DL TL
Sbjct: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
Query: 524 VQSQSLQLQILEEKNKNLQE---ALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTV 580
V+ + E K KNL E L +T KL + KK Q+ Q + + E++ V T+
Sbjct: 968 VEKEK---HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 581 QSLQQKVERCLED---------GIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQ--DE 629
+ K+E+ ++D IR+ + AK+ + E D Q T D QQ ++
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKR-KLEGDLKLAQESTMDIENDKQQLDEK 1083
Query: 630 IDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQG 689
+ + E+ +Q K+ E+ ++ +++++ + ++ LE + + + +
Sbjct: 1084 LKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEE-----LEEEIEAERASRAKAEK 1138
Query: 690 QEPDQSRQQTVLSKR 704
Q D SR+ +S+R
Sbjct: 1139 QRSDLSRELEEISER 1153
Score = 60.1 bits (144), Expect = 8e-09
Identities = 77/351 (21%), Positives = 149/351 (42%), Gaps = 55/351 (15%)
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
+K++L+EKLK ++ +S L+ K + E + Q++I+ L+ + +L ++++++
Sbjct: 1076 DKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE--EEIEAERASR 1133
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
E++ +L L + ++LEE Q+ KK+E E QK+ R L
Sbjct: 1134 AKAEKQRSDLSRELEEISERLEEAGGA---TSAQIEMNKKREAEF--------QKMRRDL 1182
Query: 592 EDG----------IRLPMLDA-KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSM 640
E+ +R D+ +L + DNL++ + K + EID + ++++
Sbjct: 1183 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETV 1242
Query: 641 ---QGKLSKEKLTTQKMMEELEKKERNVQRLTKALL-----------ENQRQTDETCSLL 686
+G L K + + E++ KE QRL L E RQ DE +L+
Sbjct: 1243 SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLV 1302
Query: 687 DQGQEPDQS-RQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKAL---CSILNQRAQGKEP 742
Q Q+ QQ KR L ++ K S L++ C +L ++ + ++
Sbjct: 1303 SQLSRGKQAFTQQIEELKRQL------EEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356
Query: 743 NLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDR 793
+ L A N + TK +D Q +++E + ++ R
Sbjct: 1357 AKAELQ-------RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Score = 57.0 bits (136), Expect = 7e-08
Identities = 102/484 (21%), Positives = 199/484 (41%), Gaps = 68/484 (14%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQ---HAMLGHYVNCEDSYVAS 417
E K KE L + + + +++ +T + E+ D +L+ Q ++ C+
Sbjct: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEK-NDLQLQVQAEADSLADAEERCDQLIKTK 916
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 477
+Q + + + +E +++ ++KL E+ + + L+ L+ +EK E
Sbjct: 917 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEK 537
K+K ++ L + K +++ K Q A TLDD+Q++ ++ L +
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQE---------AHQQTLDDLQAEEDKVNTLTKA 1027
Query: 538 NKNLQEALIDTEKKLEEIKKQCQDKE-----------------------TQLICQKKKEK 574
L++ + D E LE+ KK D E Q + +K K+K
Sbjct: 1028 KIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKK 1087
Query: 575 ELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQ--QNETASKI-IDSQQDEID 631
E + LQ K+E G++L K+LQ + L + + E AS+ + Q+ ++
Sbjct: 1088 EF--EMSGLQSKIEDEQALGMQL-QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 632 RMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETC-------- 683
R E++ + +L + T +E +K+E Q++ + L E Q + T
Sbjct: 1145 R---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHA 1201
Query: 684 -SLLDQGQEPDQ-SRQQTVLSKRPLFDLTVIDQLFKEM---SCCLFDLKALCSILNQR-- 736
S+ + G++ D R + L K ID L M S +L+ +C L +
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 737 -AQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRR-------DIDELRT 788
+ KE L+ + + +TE+ + L +K + V QL R I+EL+
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKR 1321
Query: 789 TISD 792
+ +
Sbjct: 1322 QLEE 1325
Score = 53.9 bits (128), Expect = 6e-07
Identities = 75/351 (21%), Positives = 143/351 (40%), Gaps = 41/351 (11%)
Query: 380 RQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP-QYENTSLQTPFSEESVSH 438
+QK + TH E R+ L N + + L+ + EN +LQ S+ +
Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520
Query: 439 SQQGEFEQKLASTEKEVLQLNEFLKQRL-----SLFSEEKKKLEEKLKTRDRYISSLKKK 493
++ G+ +L +K+V Q L+ L SL EE K L +L+ +K
Sbjct: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
Query: 494 CQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN--------------- 538
+K+ E ++ K+ I +E + L ++ +++L+ E +
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
Query: 539 -------KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
+N Q L DT+ L++ + +D + QL +++ L ++ L+ +E+
Sbjct: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
Query: 592 EDG--IRLPMLDAKQ----LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLS 645
+LDA + L +N +L + I Q E++ +I E ++ + K
Sbjct: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760
Query: 646 KEKLTTQKMMEELEKK-------ERNVQRLTKALLENQRQTDETCSLLDQG 689
K M EEL+K+ ER + L + + + Q + DE L +G
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1811
Score = 52.8 bits (125), Expect = 1e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 34/282 (12%)
Query: 439 SQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISS--------- 489
++ GE+ ++L + V QL+ + E K++LEE++K + +
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345
Query: 490 -LKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDT 548
L+++ ++E E E QR + +A T + + + + LEE K L + L D
Sbjct: 1346 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQDA 1404
Query: 549 EKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNE 608
E+ +E + +C E K ++ L V+ L VER LD KQ +N
Sbjct: 1405 EEHVEAVNAKCASLE-------KTKQRLQNEVEDLMIDVER---TNAACAALDKKQ-RNF 1453
Query: 609 NDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELE---KKERNV 665
+ L + + + E++ E +S+ +L K K ++ +++LE ++ +N+
Sbjct: 1454 DKILAEWKQKC----EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNL 1509
Query: 666 QR----LTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSK 703
Q+ LT+ + E ++ E + Q E ++S Q L +
Sbjct: 1510 QQEISDLTEQIAEGGKRIHELEKIKKQ-VEQEKSELQAALEE 1550
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/346 (21%), Positives = 150/346 (43%), Gaps = 59/346 (17%)
Query: 477 EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEE 536
E+++ K++ K + KE + ++ TL + DL VQ+++ L EE
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL--QVQAEADSLADAEE 907
Query: 537 KNKNLQEALIDTEKKLEEIKKQCQDKE---TQLICQKKKEKELVTTVQSLQQKVERCLED 593
+ L + I E K++E+ ++ +D+E +L +K+K LED
Sbjct: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRK------------------LED 949
Query: 594 GIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQ---GKLSKEKLT 650
+ +L+ + D+L K + ++++ + E+ + KL+KEK
Sbjct: 950 -------ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002
Query: 651 T----QKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPL 706
Q+ +++L+ +E V LTKA ++ ++Q D+ L+Q + + R +KR L
Sbjct: 1003 LQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK---KIRMDLERAKRKL 1059
Query: 707 -FDLTVI-----------DQLFKEMSCCLFDLKALCS-ILNQRAQGKEPNLSLLLGIRSM 753
DL + QL +++ F++ L S I +++A G + L I+ +
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALG----MQLQKKIKEL 1115
Query: 754 NCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDRYAQDMG 799
EE E + E ++ ++ + R D+ IS+R + G
Sbjct: 1116 QARIEELEEEIEAERASRAKAE--KQRSDLSRELEEISERLEEAGG 1159
Score = 38.1 bits (87), Expect = 0.033
Identities = 37/164 (22%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Query: 547 DTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSL-QQKVERCLEDGIRLPML-DAKQ 604
+TEK++ +K++ + + +L + K KEL + +L Q+K + L+ L DA++
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE 907
Query: 605 LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEEL------ 658
++ + Q E K + + ++ + + E+ + + KL E +K +++L
Sbjct: 908 RCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK 967
Query: 659 -EKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVL 701
EK++ + K L E DET + L + ++ Q Q L
Sbjct: 968 VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 71.2 bits (173), Expect = 3e-12
Identities = 85/407 (20%), Positives = 185/407 (45%), Gaps = 56/407 (13%)
Query: 303 QLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWES 362
QL L+ R E + L P QQ Q+E R G E QS S Q +
Sbjct: 238 QLNVKDLK-RKLERAQLLLPQQQLQVEADRLGKEL----------QSVSAKLQAQVEENE 286
Query: 363 MLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQY 422
+ + L +Q+E + RQ+++I E++ + EL+ ++ Q
Sbjct: 287 LWNL---LNQQQEEKMWRQEEKIQEQEEKMCEQELK-------------------IREQE 324
Query: 423 ENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL---EEK 479
E + +E H Q E+K+ E ++ + E ++++ E+++K+ EEK
Sbjct: 325 EKM-----WRQEEKMHEQ----EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 480 LKTRDRYISSLKKKC----QKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILE 535
++ +D I +++ +K EQ +++Q ++ EK + + + ++ Q ++ E
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQE 433
Query: 536 EKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKV---ERCLE 592
EK + L+E + D E+KL E++++ Q++E ++ Q++K + +Q ++K E+ L+
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 593 DGIRLPMLDAKQLQNENDNLRQQN--ETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLT 650
++ + K + E Q+ + + + Q++++ + + + K+ ++++
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 651 TQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
Q++ E L K + + L A E+ Q T + + Q + Q Q
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/419 (18%), Positives = 187/419 (44%), Gaps = 31/419 (7%)
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSY-------VASLQPQYENTS 426
+++ +R + I D EL+ ++A L + +S V L+ + E
Sbjct: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ 252
Query: 427 LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK-KLEEKLKTRDR 485
L P + V + G+ Q +++ + ++ NE L L+ EEK + EEK++ ++
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENE-LWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 486 YISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEAL 545
+ + K +++ E+ ++ ++ E+ + + D + Q +++ EEK + +E +
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKM 369
Query: 546 IDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQL 605
E+K+ E ++ Q++E ++ Q++K +E Q + E+ + + +++
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 606 QNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK--KER 663
+ + +R+ E + ++ ++M E + MQ + K + +K+ E+ EK ++
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 664 NVQRLTKALLENQ----RQTDETCSLLDQGQEPDQSRQ-QTVLSKRPLFDLTVIDQLFKE 718
+ + + + E + RQ ++ ++ QE ++ Q Q + L ++ +E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 719 MSCCLFDLKALCSILNQRAQ-----GKE------PNLSLLLGI--RSMNCSAEETENDH 764
L +L+ L Q+A+ G+E P L+ +L + +S + + + DH
Sbjct: 550 QEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 46.2 bits (108), Expect = 1e-04
Identities = 48/210 (22%), Positives = 94/210 (44%), Gaps = 22/210 (10%)
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
K D SS KK+ +K +E+N ++R+ + +L L +V +Q L E+ +
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWL----RLGEVTAQKRPENSLLEETLH 181
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPML 600
A + +E++ K+ +L ++EL LQ+K +RL
Sbjct: 182 FDHA-VRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEK--------LRLVES 232
Query: 601 DAKQLQNENDNLRQQNETASKIIDSQ--QDEIDRMILEIQSMQGKLSKE-------KLTT 651
+ ++Q +L+++ E A ++ Q Q E DR+ E+QS+ KL + L
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 652 QKMMEELEKKERNVQRLTKALLENQRQTDE 681
Q+ E++ ++E +Q + + E + + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIRE 322
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 71.2 bits (173), Expect = 3e-12
Identities = 85/407 (20%), Positives = 185/407 (45%), Gaps = 56/407 (13%)
Query: 303 QLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWES 362
QL L+ R E + L P QQ Q+E R G E QS S Q +
Sbjct: 238 QLNVKDLK-RKLERAQLLLPQQQLQVEADRLGKEL----------QSVSAKLQAQVEENE 286
Query: 363 MLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQY 422
+ + L +Q+E + RQ+++I E++ + EL+ ++ Q
Sbjct: 287 LWNL---LNQQQEEKMWRQEEKIQEQEEKMCEQELK-------------------IREQE 324
Query: 423 ENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL---EEK 479
E + +E H Q E+K+ E ++ + E ++++ E+++K+ EEK
Sbjct: 325 EKM-----WRQEEKMHEQ----EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 480 LKTRDRYISSLKKKC----QKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILE 535
++ +D I +++ +K EQ +++Q ++ EK + + + ++ Q ++ E
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQE 433
Query: 536 EKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKV---ERCLE 592
EK + L+E + D E+KL E++++ Q++E ++ Q++K + +Q ++K E+ L+
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 593 DGIRLPMLDAKQLQNENDNLRQQN--ETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLT 650
++ + K + E Q+ + + + Q++++ + + + K+ ++++
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 651 TQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
Q++ E L K + + L A E+ Q T + + Q + Q Q
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Score = 57.8 bits (138), Expect = 4e-08
Identities = 78/419 (18%), Positives = 187/419 (44%), Gaps = 31/419 (7%)
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSY-------VASLQPQYENTS 426
+++ +R + I D EL+ ++A L + +S V L+ + E
Sbjct: 193 EKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ 252
Query: 427 LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK-KLEEKLKTRDR 485
L P + V + G+ Q +++ + ++ NE L L+ EEK + EEK++ ++
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENE-LWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 486 YISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEAL 545
+ + K +++ E+ ++ ++ E+ + + D + Q +++ EEK + +E +
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKM 369
Query: 546 IDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQL 605
E+K+ E ++ Q++E ++ Q++K +E Q + E+ + + +++
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 606 QNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK--KER 663
+ + +R+ E + ++ ++M E + MQ + K + +K+ E+ EK ++
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 664 NVQRLTKALLENQ----RQTDETCSLLDQGQEPDQSRQ-QTVLSKRPLFDLTVIDQLFKE 718
+ + + + E + RQ ++ ++ QE ++ Q Q + L ++ +E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
Query: 719 MSCCLFDLKALCSILNQRAQ-----GKE------PNLSLLLGI--RSMNCSAEETENDH 764
L +L+ L Q+A+ G+E P L+ +L + +S + + + DH
Sbjct: 550 QEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/210 (22%), Positives = 94/210 (44%), Gaps = 22/210 (10%)
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
K D SS KK+ +K +E+N ++R+ + +L L +V +Q L E+ +
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWL----RLGEVTAQKRPENSLLEETLH 181
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPML 600
A + +E++ K+ +L ++EL LQ+K +RL
Sbjct: 182 FDHA-VRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEK--------LRLVES 232
Query: 601 DAKQLQNENDNLRQQNETASKIIDSQ--QDEIDRMILEIQSMQGKLSKE-------KLTT 651
+ ++Q +L+++ E A ++ Q Q E DR+ E+QS+ KL + L
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 652 QKMMEELEKKERNVQRLTKALLENQRQTDE 681
Q+ E++ ++E +Q + + E + + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIRE 322
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 71.2 bits (173), Expect = 3e-12
Identities = 70/376 (18%), Positives = 174/376 (46%), Gaps = 36/376 (9%)
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWES--MLKIKEGLLRQKEIVIDRQK 382
+++ + R+ ET + +Q + Q+ +W+ + + KE L Q+++ Q+
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM--QEQE 452
Query: 383 QQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQG 442
++I E+IRD E M G + + ++ + +
Sbjct: 453 EKIWEQEEKIRDQE-----EMWGQE-----------KKMWRQEKMREQEDQMWEQEEKMR 496
Query: 443 EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNK 502
+ EQK+ E+ + + +E L+++ E+KK +++ K R+ + ++K + E+
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 503 EKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDK 562
++ R+ EK + + + Q + +Q Q EEK + +E + + E+K++E +++ ++
Sbjct: 557 REEERMREREKKMREEEEMMREQEEKMQEQ--EEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 563 ETQLICQKKKEK------ELVTTVQSLQQKVERCLEDGIRLPMLDAK------QLQNEND 610
E ++ Q++++K + + +Q++ E+ E ++ + K ++Q + +
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 611 NLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKM--MEELEKKERNVQRL 668
+R+Q E + +++ ++M + + M G+ K +KM EE+ +KE ++
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Query: 669 TKALLENQRQTDETCS 684
+ + E + +E CS
Sbjct: 735 KEKMQERLPEHEERCS 750
Score = 68.9 bits (167), Expect = 2e-11
Identities = 77/346 (22%), Positives = 164/346 (47%), Gaps = 29/346 (8%)
Query: 355 QDFSKW--ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNE--------LRAQHAML 404
Q+ W E L+ +EG +R++E + RQ++++ + +R+ E LR Q +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 405 GHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQ 464
++ Q E Q E Q E EQK+ E+ + + +E L++
Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEERLWE--QEKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 465 RLSLFSEEKK--KLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLD 522
+ E++K + EEK++ +R I +KK ++E E +E++ +++ E+ +
Sbjct: 371 KEERMREQEKMWEQEEKMQEEER-IREREKKMREEEETMREQEEKMQKQEE------NMW 423
Query: 523 DVQSQSLQLQILEEKNKNL--QEALIDTEKKLEEIKKQCQDKETQLICQKKK--EKELVT 578
+ + + Q Q L E+ + L QE + + E+K+ E +++ +D+E ++ Q+KK +E +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE-EMWGQEKKMWRQEKMR 482
Query: 579 TVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDS-QQDEIDRMILEI 637
+ + E + D + +++ +++ LR++ E + QQ+E R +
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 638 QSMQGKL--SKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDE 681
Q + K +EK+ ++ M E EKK R + + + E ++ +E
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
Score = 65.9 bits (159), Expect = 1e-10
Identities = 67/303 (22%), Positives = 147/303 (48%), Gaps = 23/303 (7%)
Query: 412 DSYVASLQPQYENTSLQ----TPFSEESVSHSQQGEFEQKLASTEKEVLQLN-EFLKQRL 466
D Y+ L + + SL+ T +EE + + + + +LA +EK +QLN + LK++L
Sbjct: 158 DRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKL 217
Query: 467 S-----LFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTL 521
L + L+E++ ++ + +KK +K+ E+ ++ R+ E + +
Sbjct: 218 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK 277
Query: 522 DDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQ 581
Q + L+ Q EK QE + +KKL E ++Q Q++E ++ Q++K +E +
Sbjct: 278 MRRQEKRLREQ---EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE---QEE 331
Query: 582 SLQQKVERCLEDGIRL-----PMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILE 636
+ ++ ER E ++ M D ++ E D ++ E + + ++ ++M E
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 637 --IQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQ 694
I+ + K+ +E+ T ++ E+++K+E N+ + + QR ++ L +Q + +Q
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 695 SRQ 697
+
Sbjct: 452 EEK 454
Score = 65.1 bits (157), Expect = 3e-10
Identities = 58/301 (19%), Positives = 147/301 (48%), Gaps = 21/301 (6%)
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSE 433
+E+ +R + I + EL+ ++A L + +S + +Q + + ++
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 434 ESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKK 493
+ Q ++++ E+E+ + + ++++ E+ + EE+L+ ++ + ++K
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ----EEKMWRQEERLREQEGKMREQEEK 277
Query: 494 CQKESEQNKEKQRRIETLEKYLADLPTL----DDVQSQSLQLQILEEKNKNLQEALIDTE 549
+++ ++ +E+++ + EK L + L + +Q Q ++ EEK + +E + E
Sbjct: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Query: 550 KKLEEIKKQCQDKETQLICQKK---------KEKELVTTVQSLQQKVERCLEDGIRLPML 600
++L E +KQ +++E ++ Q++ +EKE Q + E +++ R+
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 601 DAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEK 660
+ K+++ E + +R+Q E K ++ ++ ++ E Q + KEKL Q+ M+E E+
Sbjct: 398 E-KKMREEEETMREQEEKMQKQEENMWEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEE 453
Query: 661 K 661
K
Sbjct: 454 K 454
Score = 65.1 bits (157), Expect = 3e-10
Identities = 69/348 (19%), Positives = 165/348 (47%), Gaps = 37/348 (10%)
Query: 367 KEGLLRQKEIVIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVASLQPQYEN 424
+E LR++E I +Q++++ ER+R+ E +R Q + L+ Q +
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 425 TSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFL-KQRLSLFSEEKKKLEEKLKTR 483
Q E+ Q E E+K+ E+++ + E + +Q L+ +EK+ E++ K R
Sbjct: 299 LREQKKLREQ---EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 484 DRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQE 543
D+ +++ ++ E+ +EK+ R+ EK ++ + +++ E+K + +E
Sbjct: 356 DQ-----EERMWEQDERLREKEERMREQEKMWEQ----EEKMQEEERIREREKKMREEEE 406
Query: 544 ALIDTEKKLEEIKKQCQDKETQLICQKK--KEKELVTTVQSLQQKVERCLED-------- 593
+ + E+K+++ ++ ++E + Q++ ++KE + + +Q++ E+ E
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 594 ---GIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLT 650
G M ++++ + D + +Q E D+ +RM + + ++ K +E++
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK--EERMR 524
Query: 651 TQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQ 698
QK M + E+K R ++ Q Q +T ++ +E ++ R++
Sbjct: 525 EQKKMWQQEEKMREEKK-------TQEQEKKTWDQEEKMREEERMRER 565
Score = 58.9 bits (141), Expect = 2e-08
Identities = 47/255 (18%), Positives = 127/255 (49%), Gaps = 38/255 (14%)
Query: 433 EESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL---EEKLKTRDRYISS 489
EE + ++ + ++K ++E ++ E +++R EE++ + EEK++ ++ +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 490 LKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTE 549
++K ++ E+ +E++ ++ E+ + + D +Q Q + EEK + +E + + E
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNEN 609
+K+ E +++ +++E ++ Q++K +E +++Q +
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMRE-------------------------QEEKMQGQE 687
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERN-VQRL 668
+ +R+Q E + + ++M + + M G+ +EK+ Q+ M E E++ R+ +++
Sbjct: 688 EKMREQEE-------KMRGQEEKMWGQEEKMWGQ--EEKMWGQEEMREKEERIRDQKEKM 738
Query: 669 TKALLENQRQTDETC 683
+ L E++ + E C
Sbjct: 739 QERLPEHEERCSEPC 753
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 71.2 bits (173), Expect = 3e-12
Identities = 100/449 (22%), Positives = 202/449 (44%), Gaps = 63/449 (14%)
Query: 392 IRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTS-------LQTPFSEESVSHSQQGEF 444
I + EL+A+ ++G + E +A L+ QY + LQ + + Q+ +
Sbjct: 78 ILEGELQARDEVIG-ILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIY 136
Query: 445 EQKLASTEK--------------EVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSL 490
E+ + +K ++L + +Q + EEK+K +E ++ D +I L
Sbjct: 137 EKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLL 196
Query: 491 KKKCQK-----------ESEQNKEKQRRIETLEKYLADLPT-----LDDVQSQSLQLQIL 534
+++C++ + E+ +EK++R+ TL++ L L + +D+ Q + QL +
Sbjct: 197 EQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQ 256
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
+K + L +T KL + + Q++E + + EKEL T Q +D
Sbjct: 257 RQKIQELTTNAKETHTKLALAEARVQEEEQK---ATRLEKELQTQTTKFHQD-----QDT 308
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMIL----EIQSMQGKLSKEKLT 650
I M ++N L+Q+ S+ ID + +E +R + E+Q ++ K+SK +
Sbjct: 309 I---MAKLTNEDSQNRQLQQKLAALSRQID-ELEETNRSLRKAEEELQDIKEKISKGEYG 364
Query: 651 TQKMM---EELEKKERNVQRLTKALLENQRQTDETCSLLDQG--QEPDQSRQQTVLSKRP 705
+M EEL K+ +++ + L++ + Q + L++ Q D + LSKR
Sbjct: 365 NAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKR- 423
Query: 706 LFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSL-LLGIRSMNCSAEETENDH 764
+ L ++ F + + LK C++ +R K+ + L L +R A E+ +
Sbjct: 424 IMALEKLEDAFNKSKQECYSLK--CNLEKERMTTKQLSQELESLKVRIKELEAIESRLEK 481
Query: 765 STETLTKKLSDVCQLRRDIDELRTTISDR 793
+ TL + L+ + L + R T+S++
Sbjct: 482 TEFTLKEDLTKLKTLTVMFVDERKTMSEK 510
Score = 50.8 bits (120), Expect = 5e-06
Identities = 94/477 (19%), Positives = 198/477 (41%), Gaps = 53/477 (11%)
Query: 375 EIVIDRQKQQITHLHERIRDNELRA---QHAMLGHYVNCEDSYVASLQPQYENTSLQTPF 431
E + ++Q+ T L + ++ + Q ++ N EDS LQ + S Q
Sbjct: 278 EARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDE 336
Query: 432 SEESVSHSQQGEFE-----QKLASTEKE----VLQLNEFLKQRLSLFSEEKKKLEEKLKT 482
EE+ ++ E E +K++ E + ++ E K+ L + ++++ ++ + +
Sbjct: 337 LEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQC 396
Query: 483 RDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDV------QSQSLQLQILEE 536
RD L K+ ++E+ Q+K+ + +E L K + L L+D + SL+ + +E
Sbjct: 397 RD-----LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKE 451
Query: 537 KNKNLQ-----EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVT-------TVQSLQ 584
+ Q E+L K+LE I+ + + E L K K L T+
Sbjct: 452 RMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 585 QKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKL 644
+K E L+ ++ ++ + L ++ + A K ++++ + E ++ KL
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 645 SKEKLTTQKMMEE---LEKKERNVQRLTKALLENQRQTD---ETCSLLDQGQEPDQSRQQ 698
E+ ++ L+ + ++++ + K L+N+ D T +L + + + Q+
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQE 631
Query: 699 TVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAE 758
K L D+ I+ + L+ + +AQ L + + AE
Sbjct: 632 VERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAE 691
Query: 759 ETENDHSTETLTKKLSD----VCQLRRDIDELRTTISDRYAQD------MGDNCITQ 805
+TE H + L K+L + L R++D L+ I + A + GD+ + Q
Sbjct: 692 KTETSHE-QWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSVLQ 747
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 71.2 bits (173), Expect = 3e-12
Identities = 100/449 (22%), Positives = 202/449 (44%), Gaps = 63/449 (14%)
Query: 392 IRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTS-------LQTPFSEESVSHSQQGEF 444
I + EL+A+ ++G + E +A L+ QY + LQ + + Q+ +
Sbjct: 78 ILEGELQARDEVIG-ILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIY 136
Query: 445 EQKLASTEK--------------EVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSL 490
E+ + +K ++L + +Q + EEK+K +E ++ D +I L
Sbjct: 137 EKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLL 196
Query: 491 KKKCQK-----------ESEQNKEKQRRIETLEKYLADLPT-----LDDVQSQSLQLQIL 534
+++C++ + E+ +EK++R+ TL++ L L + +D+ Q + QL +
Sbjct: 197 EQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQ 256
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
+K + L +T KL + + Q++E + + EKEL T Q +D
Sbjct: 257 RQKIQELTTNAKETHTKLALAEARVQEEEQK---ATRLEKELQTQTTKFHQD-----QDT 308
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMIL----EIQSMQGKLSKEKLT 650
I M ++N L+Q+ S+ ID + +E +R + E+Q ++ K+SK +
Sbjct: 309 I---MAKLTNEDSQNRQLQQKLAALSRQID-ELEETNRSLRKAEEELQDIKEKISKGEYG 364
Query: 651 TQKMM---EELEKKERNVQRLTKALLENQRQTDETCSLLDQG--QEPDQSRQQTVLSKRP 705
+M EEL K+ +++ + L++ + Q + L++ Q D + LSKR
Sbjct: 365 NAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKR- 423
Query: 706 LFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSL-LLGIRSMNCSAEETENDH 764
+ L ++ F + + LK C++ +R K+ + L L +R A E+ +
Sbjct: 424 IMALEKLEDAFNKSKQECYSLK--CNLEKERMTTKQLSQELESLKVRIKELEAIESRLEK 481
Query: 765 STETLTKKLSDVCQLRRDIDELRTTISDR 793
+ TL + L+ + L + R T+S++
Sbjct: 482 TEFTLKEDLTKLKTLTVMFVDERKTMSEK 510
Score = 50.8 bits (120), Expect = 5e-06
Identities = 94/477 (19%), Positives = 198/477 (41%), Gaps = 53/477 (11%)
Query: 375 EIVIDRQKQQITHLHERIRDNELRA---QHAMLGHYVNCEDSYVASLQPQYENTSLQTPF 431
E + ++Q+ T L + ++ + Q ++ N EDS LQ + S Q
Sbjct: 278 EARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDE 336
Query: 432 SEESVSHSQQGEFE-----QKLASTEKE----VLQLNEFLKQRLSLFSEEKKKLEEKLKT 482
EE+ ++ E E +K++ E + ++ E K+ L + ++++ ++ + +
Sbjct: 337 LEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQC 396
Query: 483 RDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDV------QSQSLQLQILEE 536
RD L K+ ++E+ Q+K+ + +E L K + L L+D + SL+ + +E
Sbjct: 397 RD-----LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKE 451
Query: 537 KNKNLQ-----EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVT-------TVQSLQ 584
+ Q E+L K+LE I+ + + E L K K L T+
Sbjct: 452 RMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 585 QKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKL 644
+K E L+ ++ ++ + L ++ + A K ++++ + E ++ KL
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 645 SKEKLTTQKMMEE---LEKKERNVQRLTKALLENQRQTD---ETCSLLDQGQEPDQSRQQ 698
E+ ++ L+ + ++++ + K L+N+ D T +L + + + Q+
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQE 631
Query: 699 TVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAE 758
K L D+ I+ + L+ + +AQ L + + AE
Sbjct: 632 VERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAE 691
Query: 759 ETENDHSTETLTKKLSD----VCQLRRDIDELRTTISDRYAQD------MGDNCITQ 805
+TE H + L K+L + L R++D L+ I + A + GD+ + Q
Sbjct: 692 KTETSHE-QWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSVLQ 747
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 70.9 bits (172), Expect = 5e-12
Identities = 86/372 (23%), Positives = 171/372 (45%), Gaps = 62/372 (16%)
Query: 355 QDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGH---YVNCE 411
Q+ K E L++ +LRQ + + K ++ ++ + ++ Q L H E
Sbjct: 1675 QEIEKEEENLQV---VLRQ----MSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELE 1727
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQGEFE---QKLASTEKEVLQL---NEFLKQR 465
+ VA L+ + E +LQ +S Q+GE E Q L ++E+ ++ + L+
Sbjct: 1728 KTQVAVLEEKLELENLQ------QISQQQKGEIEWQKQLLERDKREIERMTAESRALQSC 1781
Query: 466 LSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLE----KYLADLPTL 521
+ S+EK+ L+EK ++ ++ K+ E +K +Q +E LE K +L L
Sbjct: 1782 VECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQL 1841
Query: 522 D--------DVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQC------QD----KE 563
+ D+ + QLQ E +LQE L + + L K+ QD ++
Sbjct: 1842 NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQ 1901
Query: 564 TQLI------------CQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDA--KQLQNEN 609
T+L CQK++E + +Q LQ ++E E+ ++L + ++LQ E
Sbjct: 1902 TRLQKDISEWANRFEDCQKEEETKQ-QQLQVLQNEIE---ENKLKLVQQEMMFQRLQKER 1957
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLT 669
++ + ET+ + QQ ++++ + + +S ++ + L ++ + L+++ER + L
Sbjct: 1958 ESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLE 2017
Query: 670 KALLENQRQTDE 681
K L + +RQ E
Sbjct: 2018 KTLSQTKRQLSE 2029
Score = 56.6 bits (135), Expect = 9e-08
Identities = 105/494 (21%), Positives = 191/494 (38%), Gaps = 90/494 (18%)
Query: 251 PVDMTYSALPESKPIMTSSEAFEPPKYL------------MLGQQAVGGV----PIQPSV 294
P M Y+ LP+ P+ + PP L + G G P P+
Sbjct: 1242 PGYMMYTVLPDGSPVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNF 1301
Query: 295 RTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGY 354
L N E N E+ S + + I + + + + S RQS
Sbjct: 1302 SIPFIPMGVLHCNVPEHHNLENEVS----RLEDIMQHLKSKKREERWMRASKRQSEKEME 1357
Query: 355 QDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSY 414
+ + +L+ K+ L + ++ LH ++ + + D
Sbjct: 1358 ELHHNIDDLLQEKKSL-----------ECEVEELHRTVQKRQQQKDFI---------DGN 1397
Query: 415 VASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK 474
V SL + E E+S+ H + + ++ EK +L+ L++ L +E +
Sbjct: 1398 VESLMTELE--------IEKSLKHHE--DIVDEIECIEKTLLKRRSELREADRLLAEAES 1447
Query: 475 KL---EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
+L +EK K + K+ + +E +RR + T ++ QL
Sbjct: 1448 ELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQ---------ETAVNLVKADQQL 1498
Query: 532 QILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERC- 590
+ L+ K+L++ I E+ L+EI K K++ C KK+++L +Q LQ+ +E
Sbjct: 1499 RSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1558
Query: 591 LEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDE---IDRMI----LEIQSMQGK 643
+ L +L ++ + R + E + SQQ E +DR + E+ +QG
Sbjct: 1559 RNEDHHLQVLKESEVLLQAK--RAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1616
Query: 644 LSKEKLTTQKMME--ELEKKER-NVQRLTKALLE-------------NQRQTDETCSLLD 687
+ + K Q+ + E E E+ N R K+LLE ++R+T T L+
Sbjct: 1617 MVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLT--LIK 1674
Query: 688 QGQEPDQSRQQTVL 701
Q E ++ Q VL
Sbjct: 1675 QEIEKEEENLQVVL 1688
Score = 53.5 bits (127), Expect = 8e-07
Identities = 86/449 (19%), Positives = 185/449 (41%), Gaps = 76/449 (16%)
Query: 358 SKWESMLKIKEGL---LRQKEIVIDRQKQQITHLHERIRDNEL-----RAQHAMLGHYVN 409
S ++ + K KE L L++ + I+ ++ H + ++++E+ RA+ L V
Sbjct: 1531 SDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 1590
Query: 410 CEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLF 469
+ +A L Q + + + S+ ++ + ++ L E EV + +++ SL
Sbjct: 1591 SQQQEMAVLDRQLGHKKEELHLLQGSMVQAK-ADLQEALRLGETEVTEKCNHIREVKSLL 1649
Query: 470 SE---EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQS 526
E +K +L ++ R ++ +K++ +KE E + R+ + K+ +L +
Sbjct: 1650 EELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQ---MSKHKTELKNI----- 1701
Query: 527 QSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQK 586
L +L+ +N LQ + ++++ E++K T V L++K
Sbjct: 1702 ----LDMLQLENHELQGLKLQHDQRVSELEK--------------------TQVAVLEEK 1737
Query: 587 VERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGK--- 643
+E + LQ + + + E ++++ + EI+RM E +++Q
Sbjct: 1738 LE-------------LENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVEC 1784
Query: 644 LSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSK 703
LSKEK Q+ + EKK +R+ A EN + L+ Q
Sbjct: 1785 LSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQE------- 1837
Query: 704 RPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETEND 763
+DQL ++ D+ A+ L ++ + L ++ + + + +
Sbjct: 1838 --------LDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD-HLNLAKQDLL 1888
Query: 764 HSTETLTKKLSDVCQLRRDIDELRTTISD 792
H+T+ LS+ +L++DI E D
Sbjct: 1889 HTTKHQDVLLSEQTRLQKDISEWANRFED 1917
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/303 (19%), Positives = 127/303 (41%), Gaps = 34/303 (11%)
Query: 420 PQYENTSLQTPFSEESVSHSQQGEFEQK-LASTEKEVLQLNEFLKQRLSLFSEEKKKLEE 478
P++ N + E+ + H + + E++ + +++++ + E L + +EKK LE
Sbjct: 1316 PEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLEC 1375
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
+ + L + QK +Q +E+L L +++ + + ++
Sbjct: 1376 E-------VEELHRTVQKRQQQKDFIDGNVESLMTEL-------EIEKSLKHHEDIVDEI 1421
Query: 539 KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEK-----------ELVTTVQSLQQKV 587
+ +++ L+ +L E + + E++L C K+K K L+ T ++
Sbjct: 1422 ECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELE 1481
Query: 588 ERCLEDGIRLPMLD--AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLS 645
R E + L D + LQ + +L Q +I+ + + Q + K
Sbjct: 1482 RRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKK-- 1539
Query: 646 KEKLT--TQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLD--QGQEPDQSRQQTVL 701
KEKLT QK+ +++E ERN + L E++ + L+ + Q Q ++ VL
Sbjct: 1540 KEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVL 1599
Query: 702 SKR 704
++
Sbjct: 1600 DRQ 1602
Score = 48.1 bits (113), Expect = 3e-05
Identities = 56/286 (19%), Positives = 125/286 (43%), Gaps = 23/286 (8%)
Query: 375 EIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEE 434
E+ +++QKQ+I + I+D ++ ++ +D + ++ Q Q +
Sbjct: 516 ELQMEKQKQEIAGKQKEIKDLQIAIDS------LDSKDPKHSHMKAQKSGKEQQLDIMNK 569
Query: 435 SVSH--SQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEE-KKKLEEKLKTRDRYISSLK 491
S+ E ++A +E+ L E L + +E KK LE + Y+ ++K
Sbjct: 570 QYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIK 629
Query: 492 KKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKK 551
+ + + ++ + ETL L L +V+ + QL+I+ +N+++ L + E
Sbjct: 630 GQATQAQNECRKLRDEKETL------LQRLTEVEQERDQLEIVAMDAENMRKELAELESA 683
Query: 552 LE---EIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNE 608
L+ E+ Q + L + + + + + +++ LE RL L+ LQ E
Sbjct: 684 LQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAE 743
Query: 609 NDNLRQQNETA---SKIIDSQQDEIDRMILEIQSMQ--GKLSKEKL 649
+ RQ + A ++ + ++ E + +++ +Q L K++L
Sbjct: 744 LEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQL 789
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/332 (20%), Positives = 145/332 (43%), Gaps = 44/332 (13%)
Query: 355 QDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSY 414
+D S+W + E +++E ++QQ+ L I +N+L+ ++
Sbjct: 1906 KDISEWANRF---EDCQKEEET----KQQQLQVLQNEIEENKLKLVQ---------QEMM 1949
Query: 415 VASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLS--LFSEE 472
LQ + E SEES + + +++ EKE+ L Q LS L +EE
Sbjct: 1950 FQRLQKERE--------SEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEE 2001
Query: 473 KKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRR-IETLEKYLADLPTLDDVQSQS--L 529
+ + L+ +R+ SL+K + Q E++++ +E + LA D +++ L
Sbjct: 2002 RVRT---LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLL 2058
Query: 530 QLQILEEKNK------NLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSL 583
+ Q L E+ K +L+EAL +LE K +++ + C +K+ + Q
Sbjct: 2059 RNQFLTERKKAEKQVASLKEALKIQRSQLE---KNLLEQKQENSCIQKEMATIELVAQDN 2115
Query: 584 QQKVERCLEDGIRLPMLDA---KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSM 640
++ R +++ ++ KQ+ N+ D R+Q E + + + + D + ++++
Sbjct: 2116 HERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNL 2175
Query: 641 QGKLSKEKLTTQKMMEELEKKERNVQRLTKAL 672
L + + ++E E E ++ L + L
Sbjct: 2176 NQFLPELPADLEAILERNENLEGELESLKENL 2207
Score = 43.9 bits (102), Expect = 6e-04
Identities = 61/272 (22%), Positives = 121/272 (44%), Gaps = 40/272 (14%)
Query: 438 HSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISS----LKKK 493
HS + LA +K+ ++ K ++KL+E++ + +++ ++
Sbjct: 830 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQA 889
Query: 494 CQK--ESEQNKEKQR---RIETLEK---YLAD-LPTLDDVQSQS-LQLQILEEKNKNLQE 543
C++ E+ N +K++ RI+ +E YL + L +++++Q + LQLQ +E+ + +
Sbjct: 890 CERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILA 949
Query: 544 AL--IDTEKKLEEIKKQCQ----DKE----------------TQLICQKKKEKELVTTVQ 581
L ++ +KKLE+ K Q Q DKE +L K + K L TV
Sbjct: 950 QLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVM 1009
Query: 582 SLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNE-TASKIIDSQQDEIDRMILEIQSM 640
+ Q+ L++ R K Q D R + E + + Q+ E R+ +E +
Sbjct: 1010 KINQERAEELQEAER---FSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGV 1066
Query: 641 QGKLSKEKLTTQKMMEELEKKERNVQRLTKAL 672
+ + L +K+ E +E++ + RL L
Sbjct: 1067 GTGANSQVLEIEKLNETMERQRTEIARLQNVL 1098
Score = 38.1 bits (87), Expect = 0.033
Identities = 77/402 (19%), Positives = 168/402 (41%), Gaps = 62/402 (15%)
Query: 404 LGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK 463
L HY+ ++ SL+ E + T +E+ E E+ EK++++ E LK
Sbjct: 233 LPHYLQFTIFHLRSLE-SLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEE-LK 290
Query: 464 QRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDD 523
+ + F EE +K +D+ SLK++ + + +E + + T + L T++
Sbjct: 291 SKQTRFLEE-------IKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQ-KTIEL 342
Query: 524 VQSQSLQLQILEE----KNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTT 579
++ Q ++ +E K E L + EI K E+ I + + ++ + T
Sbjct: 343 TRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKA--PDESPYIGKSRYKRNMFAT 400
Query: 580 VQSLQQKVERCLEDGIRLPMLDA-KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQ 638
+ + +++ ++ +QL+N++ NLR +++ D ++
Sbjct: 401 ESYIIDSAQ-----AVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEK----------- 444
Query: 639 SMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQ 698
K+S + ++ +E+EK E+ + R T E +Q +E L + +
Sbjct: 445 ----KISAAQTRLSELHDEIEKAEQQILRAT----EEFKQLEEAIQL-----KKISEAGK 491
Query: 699 TVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNL-SLLLGIRSM---- 753
+L K+ L ++++L +E DL+ Q GK+ + L + I S+
Sbjct: 492 DLLYKQLSGRLQLVNKLRQE----ALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKD 547
Query: 754 ----NCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTIS 791
+ A+++ + + + K+ QL +DE+ + I+
Sbjct: 548 PKHSHMKAQKSGKEQQLDIMNKQYQ---QLESRLDEILSRIA 586
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.5 bits (171), Expect = 6e-12
Identities = 73/350 (20%), Positives = 160/350 (45%), Gaps = 44/350 (12%)
Query: 367 KEGLLRQKEIVIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVASLQPQYEN 424
+E LR++E I +Q++++ ER+R+ E +R Q + L+ Q +
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 425 TSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFL-KQRLSLFSEEKKKLEEKLKTR 483
Q E+ Q E E+K+ E+++ + E + +Q L+ +EK+ E++ K R
Sbjct: 337 LREQKELREQ---EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 484 DRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDD---VQSQSLQLQILEEKNKN 540
D+ +++ ++ E+ +EK+ R+ EK + + + +Q Q + + EEK +
Sbjct: 394 DQ-----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKK----------------KEKELVTTVQSLQ 584
+E + + EKK+ E ++ +++E ++ Q++ ++KE + + +Q
Sbjct: 449 -EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 585 QKVERCLED-----------GIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRM 633
++ E+ E G M ++++ + D + +Q E D+ +RM
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 634 ILEIQSMQGKL--SKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDE 681
+ Q + K +EK+ ++ M E EKK R + + + E ++ +E
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Score = 65.9 bits (159), Expect = 1e-10
Identities = 58/328 (17%), Positives = 158/328 (48%), Gaps = 19/328 (5%)
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSE 433
+E+ +R + I + EL+ ++A L + +S + +Q + + ++
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259
Query: 434 ESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKK 493
+ Q ++++ E+E+ + + ++++ E+ + EE+L+ ++ + ++K
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ----EEKMWRQEERLREQEGKMREQEEK 315
Query: 494 CQKESEQNKEKQRRIETLEKYLADLPTL----DDVQSQSLQLQILEEKNKNLQEALIDTE 549
++ ++ +E+++ + EK L + L + +Q Q ++ EEK + +E + E
Sbjct: 316 MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNEN 609
++L E +KQ +++E ++ + +E+ + + L++K ER E ++ +++ E
Sbjct: 376 ERLWEQEKQMREQEQKM---RDQEERMWEQDERLREKEERMREQEKMWEQVE--KMREEK 430
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLT 669
Q+ +T + Q++E I+ + K+ +E+ T ++ E+++K+E N+
Sbjct: 431 KMQEQEKKTRDQEEKMQEEE------RIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 670 KALLENQRQTDETCSLLDQGQEPDQSRQ 697
+ + QR ++ L +Q + +Q +
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/375 (17%), Positives = 167/375 (44%), Gaps = 44/375 (11%)
Query: 360 WESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVAS 417
WE + K++E Q++ R +++ ERIR+ E +R + + +
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 418 LQPQYENTSLQTPFSEESVSHSQQG---EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKK 474
+ Q E Q E+ +Q E E+K+ E+++ E Q ++ +EK
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 475 K--------LEEKLKTRDRYISSLKKKCQKESEQNKEK----------QRRIETLEKYLA 516
+ EEK++ +++ + +++ +K++++ ++K + R+ EK +
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599
Query: 517 DLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKK---- 572
+ + Q + +Q Q EEK + +E + + E+K++E +++ ++E ++ Q++K
Sbjct: 600 EEEEMMREQEEKMQEQ--EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 573 -----------EKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASK 621
E E + + +Q++ E+ E ++ +Q + D + + E + +
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE-KMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 622 IIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDE 681
+ + E + M+ E + K+ +++ Q+ EE+ ++E + + + E QR ++
Sbjct: 717 EREKKMREEEEMMRE---QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 682 TCSLLDQGQEPDQSR 696
L + + +Q +
Sbjct: 774 KEKLWEHEKMQEQEK 788
Score = 55.5 bits (132), Expect = 2e-07
Identities = 65/304 (21%), Positives = 136/304 (44%), Gaps = 34/304 (11%)
Query: 427 LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRY 486
LQ S S H + + ++L E++ L L + R ++ +EE KK +L+ +
Sbjct: 181 LQRALSAVSTRHKKADRYIEELTK-ERDALSLELY---RNTITNEELKKKNAELQEKLPL 236
Query: 487 ISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALI 546
S K + Q ++ K K R + L + +++ Q +L+ E+K + +E +
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 547 DTEKKLEEIKKQCQDKETQLICQKKK-----------------EKELVTTVQSLQQKVER 589
E++L E + + +++E ++ Q+K+ +KEL + +Q++ E+
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 590 CLEDGIRLPMLDAKQLQNEN---DNLRQQNETASKIIDS-----QQDEIDRMILEIQSMQ 641
E ++ + K + E + +Q E K+ D +QDE R E Q
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Query: 642 GKL--SKEKLTTQKMMEELEKKERNVQ---RLTKALLENQRQTDETCSLLDQGQEPDQSR 696
K+ EK+ +K M+E EKK R+ + + + + E +++ E + + +E Q +
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 697 QQTV 700
++ +
Sbjct: 477 EENM 480
Score = 52.0 bits (123), Expect = 2e-06
Identities = 70/381 (18%), Positives = 174/381 (45%), Gaps = 42/381 (11%)
Query: 325 QQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWES--MLKIKEGLLRQKEIVIDRQK 382
+++ + R+ ET + +Q + Q+ +W+ + + KE L Q+++ Q+
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM--QEQE 510
Query: 383 QQITHLHERIRDNE--------------LRAQHAMLGHYVNCEDSYVASLQPQYENTSLQ 428
++I E+IRD E +R Q + + Q E +
Sbjct: 511 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570
Query: 429 TPFSEESV-SHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKK---LEEKLKTRD 484
T E+ ++ E+++ EK++ + E ++++ E+++K EEK+ ++
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 485 RYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEA 544
+K Q++ E+ E++ ++ E+ + + L + + + + + ++E QE
Sbjct: 631 -------EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-----QEK 678
Query: 545 LIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQ 604
+ + E+K+ E +K +K+TQ +K ++E + +S++++ ++ E+ + + K
Sbjct: 679 MQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEK- 735
Query: 605 LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSK----EKLTTQKMMEELEK 660
+Q + + +++Q E + + ++ ++M E Q + + K EK+ Q+ + E E+
Sbjct: 736 MQEQEEKMQEQEEEMWEQEEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 661 KERNVQRLTKALLENQRQTDE 681
K R+ + + E R +E
Sbjct: 795 KMRDQEEKMRGQEEKMRGQEE 815
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/250 (18%), Positives = 116/250 (46%), Gaps = 15/250 (6%)
Query: 323 WQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQK 382
W+QQ++ + ++ ++ Q Q+ WE K+++ Q++ D++K
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQE-----QEEKIWEQE-KMEKKTQEQEKKTWDQEK 708
Query: 383 QQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQG 442
+ R R+ ++R + M+ +Q Q E Q EE + ++
Sbjct: 709 MREEE-SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ----EEKMWEQEEK 763
Query: 443 EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL--EEKLKTRDRYISSLKKKCQKESEQ 500
+EQ+ +KE L +E ++++ ++ +E+K EEK++ ++ + ++K + + E+
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Query: 501 NKEKQRRIETLEKYLADLPTLDDVQSQSLQ--LQILEEKNKNLQEALIDTEKKLEEIKKQ 558
++ ++ E+ + Q + ++ +Q EEK + +E + E+K+ E +++
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Query: 559 CQDKETQLIC 568
+ +E ++ C
Sbjct: 884 MRGQEEKIYC 893
Score = 38.1 bits (87), Expect = 0.033
Identities = 42/240 (17%), Positives = 110/240 (45%), Gaps = 24/240 (10%)
Query: 354 YQDFSKWESMLKIKEGLLRQKEIVIDRQKQQI-THLHERIRDNE-LRAQHAMLGHYVNCE 411
++ + E M + +E + Q+++ Q+Q+ T E++R+ E +R + +
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE 471
+Q Q E Q + E E+K+ E+++ + +Q+ L+
Sbjct: 730 REQEEKMQEQEEKMQEQ---------EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 780
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
EK + +EK+ ++ + ++K + + E+ + ++ ++ E + + Q ++
Sbjct: 781 EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE---------EKMWGQEEKM 831
Query: 532 QILEEKNKNLQEALIDTEKKLEE----IKKQCQDKETQLICQKKKEKELVTTVQSLQQKV 587
EEK +E + E+K+EE +++ +++E ++ Q++K +E ++ ++K+
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 69.7 bits (169), Expect = 1e-11
Identities = 75/347 (21%), Positives = 149/347 (42%), Gaps = 52/347 (14%)
Query: 359 KWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASL 418
++ L K+ L+ Q QQI L ++ + E +A++A L H + L
Sbjct: 1289 EYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE-ETKAKNA-LAHALQSSRHDCDLL 1346
Query: 419 QPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSEEKK 474
+ QYE + E ++ L+ EV Q + QR E KK
Sbjct: 1347 REQYEE------------EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1394
Query: 475 KLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQIL 534
KL ++L+ + ++ ++ KC + + Q +E L + DV+ + L
Sbjct: 1395 KLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL---------MLDVERSNAACAAL 1445
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
++K +N +K L E K++ ++ + +L +K+ + L T + ++ E L+
Sbjct: 1446 DKKQRNF-------DKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLD-- 1496
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKM 654
+ L+ EN NL+Q+ + Q E + I E++ ++ ++ +EK Q
Sbjct: 1497 ------QLETLRRENKNLQQEISD----LTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546
Query: 655 MEE----LEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
+EE LE +E + R+ L NQ +++ + ++ +E DQ ++
Sbjct: 1547 LEEAEASLEHEEGKILRIQLEL--NQVKSEVDRKIAEKDEEIDQLKR 1591
Score = 58.9 bits (141), Expect = 2e-08
Identities = 96/455 (21%), Positives = 192/455 (42%), Gaps = 51/455 (11%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQH---AMLGHYVNCEDSYVAS 417
E K K+ L + + + +++ +T L E+ D +L+ Q ++ CE
Sbjct: 857 EEFQKTKDELAKSEAKRKELEEKMVTLLKEK-NDLQLQVQSEADSLADAEERCEQLIKNK 915
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 477
+Q + + + EE +++ ++KL E+ + + L+ L+ +EK E
Sbjct: 916 IQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 975
Query: 478 EKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEK 537
K+K ++ L + K S++ K Q ET ++ TLDD+Q++ ++ IL +
Sbjct: 976 NKVKNLTEEMAGLDETIAKLSKEKKALQ---ETHQQ------TLDDLQAEEDKVNILTKA 1026
Query: 538 NKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRL 597
L++ + D E LE+ KK D E + +R LE ++L
Sbjct: 1027 KTKLEQQVDDLEGSLEQEKKLRMDLE----------------------RAKRKLEGDLKL 1064
Query: 598 PMLDAKQLQNENDNLRQQNE--------TASKIIDSQQDEI--DRMILEIQSMQGKLSKE 647
++N+ L ++ E SKI D Q EI + I E+Q+ +L +E
Sbjct: 1065 AQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE 1124
Query: 648 KLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSL---LDQGQEPDQSRQQTVLSKR 704
+ + EK+ ++ R + + E + S L++ +E + + + L +
Sbjct: 1125 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184
Query: 705 PLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLS-LLLGIRSMNCSAEE-TEN 762
L ++ L K+ + + +L L + Q E S L + ++ +AE ++
Sbjct: 1185 TLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKA 1244
Query: 763 DHSTETLTKKLSD-VCQLRRDIDELRTTISDRYAQ 796
+ E + + L D V +L+ +E + I+D AQ
Sbjct: 1245 KGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ 1279
Score = 52.4 bits (124), Expect = 2e-06
Identities = 74/402 (18%), Positives = 161/402 (40%), Gaps = 43/402 (10%)
Query: 314 TEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQ 373
+++ +L QQ ++D Q E + +LT + +K E + EG L Q
Sbjct: 996 SKEKKALQETHQQTLDDL-QAEEDKVNILTKAK-----------TKLEQQVDDLEGSLEQ 1043
Query: 374 KEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSE 433
++ + + + ++ + AQ + + + + + ++E ++L + +
Sbjct: 1044 EK----KLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIED 1099
Query: 434 ESVSHSQQGEFEQKLASTEKEVLQLNEFLK-QRLSLFSEEKKK--LEEKLKTRDRYISSL 490
E Q ++K+ + + +L E ++ +R S EK++ L +L+ +
Sbjct: 1100 EQAVEIQ---LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Query: 491 KKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQ------LQILEEKNKNLQEA 544
+ E NK+++ + L + L + + +L+ + L E+ NLQ
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216
Query: 545 LIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQ 604
EK+ E+K + D + E ++ + +K+ R LED + + K
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNA--------EAISKAKGNLEKMCRSLEDQVS----ELKT 1264
Query: 605 LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERN 664
+ E L + ++ E R + E ++ +LS+ K + + +EEL+ +
Sbjct: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324
Query: 665 VQRLTKALLENQRQTDETCSLLDQGQEPDQ---SRQQTVLSK 703
+ AL + + C LL + E +Q + Q LSK
Sbjct: 1325 ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1366
Score = 48.5 bits (114), Expect = 2e-05
Identities = 74/351 (21%), Positives = 145/351 (41%), Gaps = 41/351 (11%)
Query: 380 RQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP-QYENTSLQTPFSEESVSH 438
+QK + T E R+ L N + + L+ + EN +LQ S+ +
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1519
Query: 439 SQQG----EFEQKLASTEKEVLQLNEFLKQ-RLSLFSEE-------------KKKLEEKL 480
++ G E E+ E+E ++ L++ SL EE K +++ K+
Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1579
Query: 481 KTRDRYISSLKKKCQK-----ESEQNKEKQRRIETL---EKYLADLPTLDDVQSQSLQLQ 532
+D I LK+ + +S + E + R + L +K DL ++ + + +L
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 533 ILEEKN-KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
+N +N Q L +T+ L++ + +D + QL +++ L ++ L +E+
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTE 1699
Query: 592 EDG--IRLPMLDAKQ----LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLS 645
+LDA + L +N +L + + Q E++ +I E ++ + K
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 646 KEKLTTQKMMEELEKK-------ERNVQRLTKALLENQRQTDETCSLLDQG 689
K M EEL+K+ ER + L + + + Q + DE L +G
Sbjct: 1760 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1810
Score = 38.9 bits (89), Expect = 0.019
Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 31/175 (17%)
Query: 547 DTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQ 606
+TEK++ +K++ Q + +L + K KE L++K+ L++ L + Q+Q
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKE-------LEEKMVTLLKEKNDLQL----QVQ 895
Query: 607 NENDNLRQQNETASKIIDS-------------QQDEIDRMILEIQSMQGKLSKEKLTTQK 653
+E D+L E ++I + + +E + + E+ + + KL E +K
Sbjct: 896 SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
Query: 654 MMEEL-------EKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVL 701
+++L EK++ + K L E DET + L + ++ Q Q L
Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTL 1010
Score = 33.9 bits (76), Expect = 0.62
Identities = 58/293 (19%), Positives = 122/293 (41%), Gaps = 38/293 (12%)
Query: 312 RNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLL 371
RN ++ + Q ++D +G E + L R++ + W ++ E
Sbjct: 1644 RNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATL----EQTE 1699
Query: 372 RQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPF 431
R ++I +Q++ ER++ L Q+ L + ++ V+ LQ + E
Sbjct: 1700 RSRKIA----EQELLDASERVQ--LLHTQNTSLINTKKKLENDVSQLQSEVE-------- 1745
Query: 432 SEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEE-KKKLEEKLKTRDRYISSL 490
E + S+ E + K A T+ ++ +Q S E KK LE+ +K +
Sbjct: 1746 --EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803
Query: 491 --------KKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQIL----EEKN 538
KK+ QK + +E + +E +K A+ + ++ +++ L EE
Sbjct: 1804 EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAE--AVKGLRKHERRVKELTYQTEEDR 1861
Query: 539 KN---LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE 588
KN LQ+ + + K++ K+Q ++ E Q K ++L ++ +++ +
Sbjct: 1862 KNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAD 1914
Score = 30.0 bits (66), Expect = 8.9
Identities = 36/210 (17%), Positives = 88/210 (41%), Gaps = 15/210 (7%)
Query: 378 IDRQKQQITHLHERIRDNELRAQHA-----MLGHYVNCEDSYVASLQPQYENTSLQTPFS 432
+ + + ++ + + R+ E +A+ A M+ + E A L+ +N
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 433 EESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKK 492
+ + ++Q L +K++ +L +++ E+K+ E +K ++ +K+
Sbjct: 1797 QHRLDEAEQ----LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852
Query: 493 KCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKL 552
+ E K R + ++K A V+S Q + EE++ + +L
Sbjct: 1853 LTYQTEEDRKNVLRLQDLVDKLQAK------VKSYKRQAEEAEEQSNANLSKFRKLQHEL 1906
Query: 553 EEIKKQCQDKETQLICQKKKEKELVTTVQS 582
EE +++ E+Q+ + K +E+ T + +
Sbjct: 1907 EEAEERADIAESQVNKLRVKSREVHTKISA 1936
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 69.3 bits (168), Expect = 1e-11
Identities = 102/462 (22%), Positives = 192/462 (41%), Gaps = 68/462 (14%)
Query: 356 DFSKWESMLKIKEG----LLRQKEIVID---RQKQQITHLHERIR---DNELRAQHAMLG 405
DF+ + L+ + G L +KE +I R K T E ++ + E +A++A L
Sbjct: 1274 DFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA-LA 1332
Query: 406 HYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK-- 463
H + L+ QYE + + E ++ L+ EV Q +
Sbjct: 1333 HALQSARHDCDLLREQYEEET------------EAKAELQRVLSKANSEVAQWRTKYETD 1380
Query: 464 --QRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTL 521
QR E KKKL ++L+ + + ++ KC + Q IE L +
Sbjct: 1381 AIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDL---------M 1431
Query: 522 DDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQ 581
DV+ + L++K +N + L + ++K EE +++L +K+ + L T +
Sbjct: 1432 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEE-------SQSELESSQKEARSLSTELF 1484
Query: 582 SLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQ 641
L+ E LE + + EN NL+++ + Q E + + E++ ++
Sbjct: 1485 KLKNAYEESLE--------HLETFKRENKNLQEEISD----LTEQLGEGGKNVHELEKVR 1532
Query: 642 GKLSKEKLTTQKMMEELEKK-ERNVQRLTKALLE-NQRQTDETCSLLDQGQEPDQSR--- 696
+L EKL Q +EE E E ++ +A LE NQ + + L ++ +E +Q++
Sbjct: 1533 KQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH 1592
Query: 697 QQTVLSKRPLFDLTV-----IDQLFKEMSCCLFDLKALCSILNQ---RAQGKEPNLSLLL 748
Q+ V S + D + ++ K+M L +++ S N+ AQ + +L LL
Sbjct: 1593 QRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL 1652
Query: 749 GIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTI 790
+ ND E + L+ +++ELR +
Sbjct: 1653 KDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1694
Score = 60.5 bits (145), Expect = 6e-09
Identities = 74/355 (20%), Positives = 160/355 (45%), Gaps = 48/355 (13%)
Query: 352 PGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCE 411
P + + K + +LK E +KE+ K++ + E + +E R + E
Sbjct: 830 PWMKLYFKIKPLLKSAE---TEKEMAT--MKEEFGRIKETLEKSEARRKEL--------E 876
Query: 412 DSYVASLQPQYENTSLQTPFSEESVSHSQQ--GEFEQKLASTEKEVLQLNEFLKQRLSLF 469
+ V+ LQ + + LQ +++++ +++ + + E +V ++NE L+ +
Sbjct: 877 EKMVSLLQEK-NDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 470 SE---EKKKLEEKLKTRDRYISSLK---KKCQKESEQNKEKQRRI--------ETLEKYL 515
+E +K+KLE++ + I L+ K +KE + K + + E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 516 ADLPTLDDVQSQSL-QLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEK 574
+ L + Q+L LQ+ E+K +L ++ + ++++Q D E L +KK
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKV-------KLEQQVDDLEGSLEQEKKVRM 1048
Query: 575 ELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEI-DRM 633
+L ++ +R LE ++L L+N+ L ++ + I+ Q +I D
Sbjct: 1049 DL--------ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100
Query: 634 ILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQ 688
+L +Q +Q KL + + +++ EELE + ++ K + R+ +E L++
Sbjct: 1101 VLALQ-LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1154
Score = 56.6 bits (135), Expect = 9e-08
Identities = 56/268 (20%), Positives = 117/268 (43%), Gaps = 17/268 (6%)
Query: 419 QPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE 478
Q + E LQ+ E S + E K+ + E Q+ ++++L+ E+ +++E+
Sbjct: 1534 QLEVEKLELQSALEEAEASLEHE---EGKILRAQLEFNQIKAEIERKLA---EKDEEMEQ 1587
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
+ R + SL+ E+ E R + +E DL ++ S + ++ +K
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME---GDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 539 -KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE------RCL 591
K+LQ L DT+ +L++ + D + + +++ L ++ L+ VE +
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 592 EDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTT 651
E + + L ++N +L Q + + Q E++ + E ++ + K K
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
Query: 652 QKMMEELEKKERNVQRLTKALLENQRQT 679
M EEL KKE++ + + +N QT
Sbjct: 1765 AMMAEEL-KKEQDTSAHLERMKKNMEQT 1791
Score = 52.0 bits (123), Expect = 2e-06
Identities = 62/305 (20%), Positives = 129/305 (42%), Gaps = 50/305 (16%)
Query: 445 EQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEE----------KLKTRDRYISSLKKKC 494
++ + E + LQL E LK++ +++ K+E+ KLK I L+++
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEEL 1124
Query: 495 QKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQI---------LEEKNKNLQEAL 545
+ E + ++ L + L ++ + + +QI ++ ++L+EA
Sbjct: 1125 EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT 1184
Query: 546 IDTEKKLEEIKKQCQDKETQL---------ICQK-KKEK-----ELVTTVQSLQQ----- 585
+ E ++K+ D +L + QK +KEK EL +++Q
Sbjct: 1185 LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK 1244
Query: 586 ----KVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQ 641
KV R LED + ++ Q ++ Q + ++ E+ R + E +++
Sbjct: 1245 ANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAK----LQTENGELARQLEEKEALI 1300
Query: 642 GKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPD---QSRQQ 698
+L++ KL+ + ME+L+++ + AL + C LL + E + ++ Q
Sbjct: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Query: 699 TVLSK 703
VLSK
Sbjct: 1361 RVLSK 1365
Score = 51.2 bits (121), Expect = 4e-06
Identities = 58/266 (21%), Positives = 111/266 (41%), Gaps = 26/266 (9%)
Query: 426 SLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDR 485
SL ++ + ++ GE ++L E + QL + K++LEE+ K ++
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA 1330
Query: 486 YISS----------LKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILE 535
+ L+++ ++E+E E QR + +A T + + + + LE
Sbjct: 1331 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ-RTEELE 1389
Query: 536 EKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGI 595
E K L + L D E+ +E + +C E K + L ++ L VER
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLE-------KTKHRLQNEIEDLMVDVER---SNA 1439
Query: 596 RLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMM 655
LD KQ +N + L + + + Q E++ E +S+ +L K K ++ +
Sbjct: 1440 AAAALDKKQ-RNFDKILAEWKQK----YEESQSELESSQKEARSLSTELFKLKNAYEESL 1494
Query: 656 EELEKKERNVQRLTKALLENQRQTDE 681
E LE +R + L + + + Q E
Sbjct: 1495 EHLETFKRENKNLQEEISDLTEQLGE 1520
Score = 47.4 bits (111), Expect = 5e-05
Identities = 66/324 (20%), Positives = 141/324 (43%), Gaps = 38/324 (11%)
Query: 477 EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEE 536
E+++ T +K+ +K + KE + ++ +L + DL VQ++ L EE
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQL--QVQAEQDNLNDAEE 905
Query: 537 KNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIR 596
+ L + I E K++E+ ++ +D+E K+++L L++ + D +
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI-----DDLE 960
Query: 597 LPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTT----Q 652
L + ++ ++ +N K + + +D +I KL+KEK Q
Sbjct: 961 LTLAKVEKEKHATEN-------KVKNLTEEMAGLDEII-------AKLTKEKKALQEAHQ 1006
Query: 653 KMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPL-FDLTV 711
+ +++L+ +E V L+K+ ++ ++Q D+ L+Q + + R +KR L DL +
Sbjct: 1007 QALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK---KVRMDLERAKRKLEGDLKL 1063
Query: 712 IDQLFKEMSCCLFDLKALCS----ILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTE 767
+ ++ L+ +NQ+ E L L ++ + EN E
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQK-----KLKENQARIE 1118
Query: 768 TLTKKLSDVCQLRRDIDELRTTIS 791
L ++L R +++LR+ +S
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLS 1142
Score = 46.2 bits (108), Expect = 1e-04
Identities = 56/274 (20%), Positives = 116/274 (42%), Gaps = 31/274 (11%)
Query: 445 EQKLASTEKEVLQLNEF---LKQRLSLFSEEKKKLEEK-------LKTRDRYISSLKKKC 494
E++ +TE +V L E L + ++ ++EKK L+E L+ + ++SL K
Sbjct: 967 EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSK 1026
Query: 495 QKESEQNKEKQRRIETLEKYLADLPTLD-----DVQSQSLQLQILEEKNKNLQEALIDTE 549
K +Q + + +E +K DL D++ + LE L+E L E
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE 1086
Query: 550 KKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNEN 609
+ + + +D++ + +KK KE ++ L++++E ++ L L E
Sbjct: 1087 FDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKL-RSDLSREL 1145
Query: 610 DNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKL---------------TTQKM 654
+ + ++ E A Q + + E Q M+ L + L + ++
Sbjct: 1146 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1205
Query: 655 MEELEKKERNVQRLTKALLENQRQTDETCSLLDQ 688
E+++ +R Q+L K E + + D+ S ++Q
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQ 1239
Score = 45.1 bits (105), Expect = 3e-04
Identities = 66/312 (21%), Positives = 138/312 (44%), Gaps = 30/312 (9%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERI-----RDNELRAQHAMLGHYVNCEDSYV 415
+ +K + LL+ +I +D + L E I R+N L+A+ L V +
Sbjct: 1642 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 1701
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKK 475
+ + TS + + HSQ + E ++ QL +++ + +E +
Sbjct: 1702 KLAEQELIETSERV-----QLLHSQNTSLINQKKKMESDLTQLQSEVEEAV----QECRN 1752
Query: 476 LEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLP-TLDDVQSQSL----- 529
EEK K + + ++ +KE + + +R + +E+ + DL LD+ + +L
Sbjct: 1753 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1812
Query: 530 QLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKE---TQLICQKKKEKELVTTVQSLQQK 586
QLQ LE + + L+ L +K+ E K + E +L Q +++K+ + +Q L K
Sbjct: 1813 QLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDK 1872
Query: 587 VERCLEDGIRLPMLDAKQLQNE-NDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLS 645
L+ ++ A++ + + N NL + + + +D ++ D ++ ++ K S
Sbjct: 1873 ----LQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE-LDEAEERADIAESQVNKLRAK-S 1926
Query: 646 KEKLTTQKMMEE 657
++ QKM +E
Sbjct: 1927 RDIGAKQKMHDE 1938
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 68.6 bits (166), Expect = 2e-11
Identities = 75/337 (22%), Positives = 146/337 (43%), Gaps = 48/337 (14%)
Query: 367 KEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTS 426
KE L+ Q QQ+ L ++ + E++A++A L H + L+ QYE +
Sbjct: 1294 KEALISQLTRGKLTYTQQLEDLKRQLEE-EVKAKNA-LAHALQSARHDCDLLREQYEEET 1351
Query: 427 LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSEEKKKLEEKLKT 482
+ E ++ L+ EV Q + QR E KKKL ++L+
Sbjct: 1352 ------------EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1399
Query: 483 RDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQ 542
+ + ++ KC + Q IE L + DV+ + L++K +N
Sbjct: 1400 AEEAVEAVNAKCSSLEKTKHRLQNEIEDL---------MVDVERSNAAAAALDKKQRNFD 1450
Query: 543 EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDA 602
+ L + ++K EE +++L +K+ + L T + L+ E LE
Sbjct: 1451 KILAEWKQKYEE-------SQSELESSQKEARSLSTELFKLKNAYEESLE--------HL 1495
Query: 603 KQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKK- 661
+ + EN NL+++ ++ + S + I E++ ++ +L EK+ Q +EE E
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSS----GKTIHELEKVRKQLEAEKMELQSALEEAEASL 1551
Query: 662 ERNVQRLTKALLE-NQRQTDETCSLLDQGQEPDQSRQ 697
E ++ +A LE NQ + + L ++ +E +Q+++
Sbjct: 1552 EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 56.6 bits (135), Expect = 9e-08
Identities = 84/421 (19%), Positives = 177/421 (42%), Gaps = 52/421 (12%)
Query: 300 LTEQLR-TNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFS 358
LTE++ + + + T++ +L QQ ++D Q E + LT +
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL-QAEEDKVNTLTKAK-----------V 1025
Query: 359 KWESMLKIKEGLLRQKEIV---IDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYV 415
K E + EG L Q++ V ++R K+++ + +L+ + N +
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKL--------EGDLKLTQESIMDLENDKQQLD 1077
Query: 416 ASLQPQ-YENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK-QRLSLFSEEK 473
L+ + +E +L +E SQ ++KL + + +L E L+ +R + EK
Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGSQ---LQKKLKELQARIEELEEELEAERTARAKVEK 1134
Query: 474 KK--LEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQ- 530
+ L +L+ + + E NK+++ + + + L + + + +L+
Sbjct: 1135 LRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK 1194
Query: 531 -----LQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQ 585
+ L E+ NLQ EK+ E K + D + + E + ++ +
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM--------EQIIKAKANLE 1246
Query: 586 KVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLS 645
K+ R LED + A++ Q ++L Q + ++ E+ R + E +++ +L+
Sbjct: 1247 KMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK----LQTENGELSRQLDEKEALISQLT 1302
Query: 646 KEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPD---QSRQQTVLS 702
+ KLT + +E+L+++ + AL + C LL + E + ++ Q VLS
Sbjct: 1303 RGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1362
Query: 703 K 703
K
Sbjct: 1363 K 1363
Score = 55.1 bits (131), Expect = 3e-07
Identities = 68/335 (20%), Positives = 143/335 (42%), Gaps = 23/335 (6%)
Query: 358 SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNE-LRAQHAMLGHYVNCEDSYVA 416
S+ ES K L + + + ++ + HL R+N+ L+ + + L + +
Sbjct: 1465 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH 1524
Query: 417 SL-----QPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE 471
L Q + E LQ+ E S + E K+ + E Q+ ++++L+ E
Sbjct: 1525 ELEKVRKQLEAEKMELQSALEEAEASLEHE---EGKILRAQLEFNQIKAEIERKLA---E 1578
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQL 531
+ +++E+ + R + SL+ E+ E R + +E DL ++ S + ++
Sbjct: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME---GDLNEMEIQLSHANRM 1635
Query: 532 QILEEKN-KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVE-- 588
+K K+LQ L DT+ +L++ + D + + +++ L ++ L+ VE
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQT 1695
Query: 589 ----RCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKL 644
+ E + + L ++N +L Q + + Q E++ + E ++ + K
Sbjct: 1696 ERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKA 1755
Query: 645 SKEKLTTQKMMEELEKKERNVQRLTKALLENQRQT 679
K M EEL KKE++ + + +N QT
Sbjct: 1756 KKAITDAAMMAEEL-KKEQDTSAHLERMKKNMEQT 1789
Score = 49.3 bits (116), Expect = 1e-05
Identities = 70/300 (23%), Positives = 139/300 (46%), Gaps = 43/300 (14%)
Query: 472 EKKKLEEKLKTRDRYISSLKKKCQKES-------EQNKEKQRRIETLEKYL-ADLPTLDD 523
+K++L+E+LK +D +++L + + E ++ KE Q RIE LE+ L A+
Sbjct: 1072 DKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Query: 524 VQSQSLQL-QILEEKNKNLQEA------LIDTEKKLE-EIKKQCQDKE--------TQLI 567
V+ L + LEE ++ L+EA I+ KK E E +K +D E T
Sbjct: 1132 VEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAA 1191
Query: 568 CQKKKEK------ELVTTVQSLQQKVERCLEDGIRLPMLDA----KQLQNENDNLRQQNE 617
+KK E + +Q ++QK+E+ + +L + D +Q+ NL +
Sbjct: 1192 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSE-FKLELDDVTSNMEQIIKAKANLEKMCR 1250
Query: 618 TASKIID---SQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLE 674
T ++ S+ +E R + ++ S + KL E ++ +L++KE + +LT+ L
Sbjct: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN---GELSRQLDEKEALISQLTRGKLT 1307
Query: 675 NQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILN 734
+Q ++ L++ + + + S R D ++ + ++E + +L+ + S N
Sbjct: 1308 YTQQLEDLKRQLEEEVKAKNALAHALQSAR--HDCDLLREQYEEETEAKAELQRVLSKAN 1365
Score = 44.7 bits (104), Expect = 3e-04
Identities = 91/463 (19%), Positives = 194/463 (41%), Gaps = 55/463 (11%)
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHA---MLGHYVNCEDSYVAS 417
E ++KE L + + + +++ ++ L E+ D +L+ Q + C+
Sbjct: 854 EEFTRLKEALEKSEARRKELEEKMVSLLQEK-NDLQLQVQAEQDNLADAEERCDQLIKNK 912
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLE 477
+Q + + + +E +++ ++KL E+ + + L+ L+ +EK E
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 478 EKLKTRDRYISSL---------KKKCQKESEQN-----KEKQRRIETLEKYLADLPTLDD 523
K+K ++ L +KK +E+ Q + ++ ++ TL K L D
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 524 VQSQSLQLQ-----ILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVT 578
SL+ + LE + L+ L T++ + +++ Q + +L KKK+ EL
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL---KKKDFEL-- 1087
Query: 579 TVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNE---TASKIIDSQQDEIDRMIL 635
+L ++E G +L K+LQ + L ++ E TA ++ + ++ R
Sbjct: 1088 --NALNARIEDEQALGSQL-QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSR--- 1141
Query: 636 EIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETC---------SLL 686
E++ + +L + T +E +K+E Q++ + L E Q + T S+
Sbjct: 1142 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVA 1201
Query: 687 DQGQEPD--QSRQQTVLSKRPLFDLTVID--QLFKEMSCCLFDLKALCSIL----NQRAQ 738
+ G++ D Q +Q + ++ F L + D +++ +L+ +C L N+
Sbjct: 1202 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Query: 739 GKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRR 781
E + + S +TEN + L +K + + QL R
Sbjct: 1262 KAEETQRSVNDLTSQRAKL-QTENGELSRQLDEKEALISQLTR 1303
Score = 42.7 bits (99), Expect = 0.001
Identities = 69/330 (20%), Positives = 133/330 (40%), Gaps = 47/330 (14%)
Query: 365 KIKEGLLRQKEIVIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVASLQPQY 422
K EG L + EI + + ++++ + L+ L V D ++
Sbjct: 1616 KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVE 1675
Query: 423 ENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLK----QRLSLFSEEKK---- 474
+L EE + +Q E +KLA E+E+++ +E ++ Q SL +++KK
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLA--EQELIETSERVQLLHSQNTSLINQKKKMDAD 1733
Query: 475 ----------------KLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADL 518
EEK K + + ++ +KE + + +R + +E+ + DL
Sbjct: 1734 LSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL 1793
Query: 519 P-TLDDVQSQSL-----QLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKK 572
LD+ + +L QLQ LE + + L+ L +K+ E K + E ++
Sbjct: 1794 QHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI------ 1847
Query: 573 EKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDR 632
KEL + ++ + R L+D + L K + + + +Q T Q E+D
Sbjct: 1848 -KELTYQTEEDRKNLLR-LQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Query: 633 M-----ILEIQSMQGKLSKEKLTTQKMMEE 657
I E Q + + + T+ + EE
Sbjct: 1906 AEERADIAESQVNKLRAKSRDIGTKGLNEE 1935
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 68.6 bits (166), Expect = 2e-11
Identities = 86/420 (20%), Positives = 185/420 (44%), Gaps = 69/420 (16%)
Query: 288 VPIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSR 347
V +Q SV TQ L E L+ T+ L ++ Q+E+ + V+T
Sbjct: 329 VSLQRSVSTQKALEEDLQIA------TKTICQLTEEKETQMEESNKARAAHSFVVT---- 378
Query: 348 QSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHY 407
++E+ + E LLR ++ +++ + Q+ +I EL+ + + L
Sbjct: 379 -----------EFETTVCSLEELLRTEQQRLEKNEDQL-----KILTMELQKKSSEL--- 419
Query: 408 VNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFE---QKLASTEKEVLQLNEFLKQ 464
E+ + + E L+ E+ + +FE ++L TE+E++ L + ++
Sbjct: 420 ---EEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREK 476
Query: 465 RL--------------SLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIET 510
+ +S+E K L+ +L+ + L C K S +NKE + ET
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQ--ET 534
Query: 511 LEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQK 570
+ L +D+ + Q + + ++ +NLQE +LE ++++ + K ++ C+
Sbjct: 535 SDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKL 594
Query: 571 KKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEI 630
K +E ++ + + +E+ LQ EN L+++ SK ++ + ++
Sbjct: 595 DKSEENCNNLRKQVENKNKYIEE-----------LQQENKALKKKGTAESKQLNVYEIKV 643
Query: 631 DRMILEIQSMQGKLSKEKLTTQKMMEELEKKERN-VQRLTKA------LLENQRQTDETC 683
+++ LE++S + K + T QK +E+ + E N ++ + KA ++ Q++ D+ C
Sbjct: 644 NKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRC 703
Score = 55.1 bits (131), Expect = 3e-07
Identities = 71/348 (20%), Positives = 141/348 (40%), Gaps = 40/348 (11%)
Query: 348 QSYSPGYQDFSKWESMLKI----KEGLLRQKEIVIDRQKQQITHLHERIR------DNEL 397
Q Y D K S+L I KE ++ +++ + ++ L E+ + +
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSI 314
Query: 398 RAQHAM----------LGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQK 447
QH + L V+ + + LQ + T E + S +
Sbjct: 315 EKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHS 374
Query: 448 LASTEKE--VLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQ 505
TE E V L E L+ + +K E++LK + + ++ ++ K+
Sbjct: 375 FVVTEFETTVCSLEELLRTE----QQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 506 RRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQ 565
+E L+K L + TL ++ Q + + E+ K ++ LI L+ +K+ D E Q
Sbjct: 431 VELEELKKVLGEKETL---LYENKQFEKIAEELKGTEQELIGL---LQAREKEVHDLEIQ 484
Query: 566 LICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDS 625
L E+ V+ L+ ++E L +L EN L Q+ + + +
Sbjct: 485 LTAITTSEQYYSKEVKDLKTELENEKLKNTELTS-HCNKLSLENKELTQETSDMTLELKN 543
Query: 626 QQDEI-------DRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQ 666
QQ++I +RM+ +I+++Q ++ + + + EEL++K V+
Sbjct: 544 QQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 53.5 bits (127), Expect = 8e-07
Identities = 71/354 (20%), Positives = 152/354 (42%), Gaps = 32/354 (9%)
Query: 350 YSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVN 409
YS Y++ K + E LRQKE + ++ I + I++ + + L
Sbjct: 106 YSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEG 165
Query: 410 CEDSYVASLQPQYENTSLQTPFSEESVSHSQQG--EFEQKLASTEKEVLQLNEFLKQRLS 467
+++ L + T +E+ + S + ++E + T + + LN +++ ++
Sbjct: 166 IQEN--KDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMIT 223
Query: 468 LFSE-----EKKKLEEKLKTRDRY--ISSLKKKCQKESEQNKEKQRRIETLEKYLADLPT 520
F E E +LE K ++ Y I L+++ +KE +KEKQ + ++
Sbjct: 224 AFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEIN-DKEKQVSLLLIQ-------- 274
Query: 521 LDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTV 580
+ + +++ L L E++++ L + K E KQ +K+ L KEL
Sbjct: 275 ITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLT------KELEDIK 328
Query: 581 QSLQQKV--ERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQ 638
SLQ+ V ++ LE+ +++ QL E + +++ A E + + ++
Sbjct: 329 VSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLE 388
Query: 639 SM----QGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQ 688
+ Q +L K + + + EL+KK ++ +TK + + +E +L +
Sbjct: 389 ELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE 442
Score = 47.4 bits (111), Expect = 5e-05
Identities = 95/527 (18%), Positives = 204/527 (38%), Gaps = 96/527 (18%)
Query: 173 TVCR--EESRNGLEKIGKAKALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKY 230
T+C+ EE +E+ KA+A S + T + + E+LR E + + K
Sbjct: 351 TICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTM 410
Query: 231 KFESCSKEDFRASSSTLRRQPVDMTYSALPESKPIMTSSEA--FEPPKYLMLGQQAVGGV 288
+ + S E + T ++ L E K ++ E +E ++ + ++ G
Sbjct: 411 ELQKKSSELEEMTKLTNNKEV------ELEELKKVLGEKETLLYENKQFEKIAEELKG-- 462
Query: 289 PIQPSVRTQMWLTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQ 348
TEQ L+ R ++++ D E + +T +S Q
Sbjct: 463 ------------TEQELIGLLQAR------------EKEVHDL----EIQLTAIT-TSEQ 493
Query: 349 SYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYV 408
YS +D + ++ +K + T L N+L ++ L
Sbjct: 494 YYSKEVKDL-----------------KTELENEKLKNTELTSHC--NKLSLENKELTQET 534
Query: 409 NCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFE--QKLASTEKEVLQLNEFLKQRL 466
+ + + Q N Q + + + Q+ E + +L +E+ Q + +K +L
Sbjct: 535 SDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKL 594
Query: 467 SLFSEEKKKLEEKLKTRDRYIS-------SLKKKCQKESEQNKEKQRRIETLEKYLADLP 519
E L ++++ +++YI +LKKK ES+Q + ++ LE
Sbjct: 595 DKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLE------- 647
Query: 520 TLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTT 579
L+ ++ +I + K +++ I E LEE+ +K K +
Sbjct: 648 -LELESAKQKFGEITDTYQKEIEDKKISEENLLEEV---------------EKAKVIADE 691
Query: 580 VQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQS 639
LQ+++++ + I + ++ +++ D + ++ ++ + S++ E + ++
Sbjct: 692 AVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEI 751
Query: 640 MQGKLSKEKLTTQKMM----EELEKKERNVQRLTKALLENQRQTDET 682
L E L+ +K + EE EK +R + T L E + + +T
Sbjct: 752 ELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQT 798
Score = 32.0 bits (71), Expect = 2.3
Identities = 35/180 (19%), Positives = 76/180 (42%), Gaps = 30/180 (16%)
Query: 521 LDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTV 580
L++ + S L ++ + +++ + TE +L + + + Q+ + Q+K +EL
Sbjct: 96 LENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQEL---- 151
Query: 581 QSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQ---------------------QNETA 619
Q +KV LE+GI+ + K L EN+ R + E
Sbjct: 152 QFGNEKVSLKLEEGIQ----ENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREET 207
Query: 620 SKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQ-KMMEELEKKERNVQRLTKALLENQRQ 678
++ + I++MI + ++ + +L K+ E+ EK + Q K + + ++Q
Sbjct: 208 RQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQ 267
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 68.6 bits (166), Expect = 2e-11
Identities = 97/459 (21%), Positives = 192/459 (41%), Gaps = 73/459 (15%)
Query: 367 KEGLLRQKEIVIDRQKQQITHLHER------IRDNELRAQHAMLGHYVNC-----EDSYV 415
KE LL+ KEI+ + I ++E+ ++ EL + + L + E+ V
Sbjct: 653 KETLLKDKEIIF---QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 416 ASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKK 475
Q L+ E+ H QQ + + E + + + LK +++ K+
Sbjct: 710 LKDQTDKMKQELEAKMDEQKNHHQQQ--VDSIIKEHEVSIQRTEKALKDQINQLELLLKE 767
Query: 476 LEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILE 535
++ LK ++ +L+ ++ + ++ +++ + Y + + Q + E
Sbjct: 768 RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQS---------ATHEQTKAYE 818
Query: 536 EKNKNLQEALIDTE-------KKLEEIKKQCQDKETQLICQK-----------KKEKELV 577
E+ LQ+ L+D E K++ E++ Q +D T+L K K+ E+
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME 878
Query: 578 TTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEI 637
V+SL Q E LEDG + KQ+ E +N+ Q K EI
Sbjct: 879 QKVKSLTQVYESKLEDGNK-EQEQTKQILVEKENMILQMREGQK-------------KEI 924
Query: 638 QSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETC--SLLDQGQEPDQS 695
+ + KLS ++ + + EE E K +N ++ + + + ++ ET LLDQ + +
Sbjct: 925 EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKE 984
Query: 696 RQQTVL---SKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQ--------GKEPNL 744
+ T L K F+ ++ ++ + S + D + NQ+ Q +E N
Sbjct: 985 LENTALELSQKEKQFNAKML-EMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELND 1042
Query: 745 SLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDI 783
+ + + +N AEE + H + L +K +V +L++ I
Sbjct: 1043 VISIWEKKLNQQAEELQEIHEIQ-LQEKEQEVAELKQKI 1080
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/401 (22%), Positives = 170/401 (42%), Gaps = 40/401 (9%)
Query: 358 SKWESMLKIK-EGLLRQKEIVIDRQKQQITHLHERI-----RDNELRAQHAMLGHYVNCE 411
S WE L + E L EI + ++Q++ L ++I E+ + L +
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ 1104
Query: 412 DSYVASLQPQYENTS--LQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLF 469
D+ + LQ Q + S + + +E+ + + E L + KE L E L + L
Sbjct: 1105 DTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLA 1164
Query: 470 SEEKKKLEE---KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQS 526
E+K+K+ E KLKT D SLK +K ++ ++K + L + LA + ++
Sbjct: 1165 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKT 1224
Query: 527 QSL-------QLQILEEKNKNLQEALIDTEKKLEEIK-----KQC--QDKETQLICQKKK 572
++L + I K + + + + ++K K C + E QL ++
Sbjct: 1225 EALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEE 1284
Query: 573 EKELVTTVQSLQQKVE------RCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQ 626
+ L + Q ++E + ++ I + + + LQ E N +Q I
Sbjct: 1285 QNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL 1344
Query: 627 QDEIDRMILEIQSMQGKLSKEKL---TTQKMMEELEKKERNVQRLTK---ALLENQRQTD 680
+ E+ I + M+ +L ++K+ + K + +L + +N L++ A+ ++Q D
Sbjct: 1345 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYD 1404
Query: 681 -ETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMS 720
E C LLDQ Q D S + LSK + L +D + S
Sbjct: 1405 EEKCELLDQVQ--DLSFKVDTLSKEKISALEQVDDWSNKFS 1443
Score = 58.5 bits (140), Expect = 2e-08
Identities = 99/480 (20%), Positives = 208/480 (43%), Gaps = 51/480 (10%)
Query: 337 TPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIR--- 393
T + L +S +++ K S + E R+ + +D Q + I E R
Sbjct: 396 TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISL 455
Query: 394 DNEL-RAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQK----L 448
EL R + ++ + +A LQ +E + +++ EF+++ L
Sbjct: 456 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVAL 515
Query: 449 ASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRI 508
++ E L++++ +Q+ SL EE + ++ + T + + Q+E+E + + +
Sbjct: 516 EKSQSEYLKISQEKEQQESLALEELELQKKAILTESE---NKLRDLQQEAETYRTRILEL 572
Query: 509 ET-LEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEK---KLEEIKKQCQD--- 561
E+ LEK L + + QS+ L + + EKNK+ +E + EK +LE +K Q QD
Sbjct: 573 ESSLEKSLQE----NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQ-QDALW 627
Query: 562 KETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASK 621
E + +++ + E+ + +Q+ E L+D ++ ++ N+ ++ +
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKD---KEIIFQAHIEEMNEKTLEKLDVKQT 684
Query: 622 IIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEEL-----EKKERNVQRLTKALLENQ 676
++S E+ ++ ++ +LS K T KM +EL E+K + Q++ + E++
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE 744
Query: 677 RQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQR 736
T L DQ Q +L K D+ KE + +L+A +R
Sbjct: 745 VSIQRTEKAL-----KDQINQLELLLKER-------DKHLKEHQAHVENLEADI----KR 788
Query: 737 AQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDELRTTISDRYAQ 796
++G+ S L + SA + T+ ++L+ + Q D++ R ++ + A+
Sbjct: 789 SEGELQQASAKLDVFQSYQSATHEQ----TKAYEEQLAQLQQKLLDLETERILLTKQVAE 844
Score = 54.7 bits (130), Expect = 3e-07
Identities = 68/333 (20%), Positives = 154/333 (46%), Gaps = 44/333 (13%)
Query: 371 LRQKEIVIDRQKQQITHLHE-RIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQT 429
L++KE+ +Q+I L +R E+ H + + + + +LQ Q + + T
Sbjct: 1842 LQEKELTCQILEQKIKELDSCLVRQKEV---HRVEMEELTSKYEKLQALQ-QMDGRNKPT 1897
Query: 430 PFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISS 489
EE+ + Q + E Q N+ L+ +L+ EK+KL +++ + +
Sbjct: 1898 ELLEENTEEKSKSHLVQPKLLSNMEA-QHND-LEFKLAGAEREKQKLGKEIVRLQKDLRM 1955
Query: 490 LKKKCQKESEQNKEK--QRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALID 547
L+K+ Q+E E K++ Q R E +++ DL +++ S Q++ E N L + +
Sbjct: 1956 LRKEHQQELEILKKEYDQEREEKIKQEQEDL----ELKHNSTLKQLMREFNTQLAQKEQE 2011
Query: 548 TEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQN 607
E ++E + Q+ E +L+ +S Q++ + L K++
Sbjct: 2012 LEMTIKETINKAQEVEAELL-------------ESHQEETNQLL-----------KKIAE 2047
Query: 608 ENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQR 667
++D+L++ + +I+D++++E+ + ++Q+ +L K K ++LE++E N
Sbjct: 2048 KDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQK------KYQQKLEQEE-NPGN 2100
Query: 668 LTKALLENQRQTDETCSLLDQGQEPDQSRQQTV 700
++E Q Q + +L+ + +Q ++ +
Sbjct: 2101 DNVTIMELQTQLAQKTTLISDSKLKEQEFREQI 2133
Score = 52.4 bits (124), Expect = 2e-06
Identities = 75/375 (20%), Positives = 156/375 (41%), Gaps = 46/375 (12%)
Query: 435 SVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKC 494
++S S+ +++ + ++ E L + SE LE +L+ ++L
Sbjct: 1237 NISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSE----LEAQLRQLTEEQNTLNISF 1292
Query: 495 QKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEE 554
Q+ + Q +EK+ +I++++ D++S + + L+++ N Q+A + E + +
Sbjct: 1293 QQATHQLEEKENQIKSMKA---------DIESLVTEKEALQKEGGNQQQAASEKESCITQ 1343
Query: 555 IKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQ 614
+KK+ + + K++ KE + SL ++ L +Q +N
Sbjct: 1344 LKKELSENINAVTLMKEELKEKKVEISSLSKQ-------------LTDLNVQLQNSISLS 1390
Query: 615 QNETASKIIDSQQDEIDRMIL-EIQSMQGK---LSKEKLTTQKMMEELEKKERNVQRLTK 670
+ E A + Q DE +L ++Q + K LSKEK++ + +++ K ++ +
Sbjct: 1391 EKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1450
Query: 671 ALLENQRQT--DETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKA 728
+ + T + L + +E + +Q L K L DQ K C LK
Sbjct: 1451 SRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEEL------DQQNKRFDC----LKG 1500
Query: 729 LCSILNQRAQGKEPNLSLLL---GIRSMNCSAEETENDHSTETLTKKLSDVCQLRRDIDE 785
+ + KE NL L R M T+ E+L + L + Q ++DI+
Sbjct: 1501 EMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ-QKDIEH 1559
Query: 786 LRTTISDRYAQDMGD 800
++ Q++G+
Sbjct: 1560 KELVQKLQHFQELGE 1574
Score = 50.8 bits (120), Expect = 5e-06
Identities = 85/422 (20%), Positives = 185/422 (43%), Gaps = 52/422 (12%)
Query: 377 VIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEESV 436
++ R+K+++ + + +D LR + A L + + LQ +++ SL+ SV
Sbjct: 166 MLQREKKKLQGILSQSQDKSLR-RIAELREELQMDQQAKKHLQEEFD-ASLEEKDQYISV 223
Query: 437 SHSQQGEFEQKLAS--TEKEVLQLNEFLKQRLSLFSEEKKKLE--EKLKTRDRYISSLKK 492
+Q +Q+L + +VL+ L+ + +F++E+ E + + +L+
Sbjct: 224 LQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLET 283
Query: 493 KCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKL 552
Q+ Q +R ET +QS Q +L + + LQE L + ++L
Sbjct: 284 LQQRVKRQENLLKRCKET-------------IQSHKEQCTLLTSEKEALQEQLDERLQEL 330
Query: 553 EEIKKQCQDKETQLICQKKKEKELVTTV----------------QSLQQKVERCLEDGIR 596
E+IK ++T+LI Q + K L+ + ++L+ K E + R
Sbjct: 331 EKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSR 390
Query: 597 LPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMME 656
+ KQ+ + + LR+Q E + + + ++ + + + KL E K +E
Sbjct: 391 I-----KQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE 445
Query: 657 ELEKKER-----NVQRLTKALLE-NQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLT 710
+ ++ER + R+ + +++ ++ ++E + L + E + +R++ L+K+ L
Sbjct: 446 KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK----LQ 501
Query: 711 VIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLT 770
++ F+E + K+ L + +Q KE SL L + A TE+++ L
Sbjct: 502 TREREFQEQMKVALE-KSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQ 559
Query: 771 KK 772
++
Sbjct: 560 QE 561
Score = 49.7 bits (117), Expect = 1e-05
Identities = 81/441 (18%), Positives = 180/441 (40%), Gaps = 31/441 (7%)
Query: 371 LRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQPQYENTSLQTP 430
L ++ ++++ + +T ++E ++ + Q V E+ + + Q + + T
Sbjct: 870 LEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQ 929
Query: 431 --FSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSE--EKKKLEEKLKTRDRY 486
++E H E+E K + EK++ E +KQ+ E +KK L+++ K +
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKM----EKVKQKAKEMQETLKKKLLDQEAKLKKEL 985
Query: 487 ISSLKKKCQKESEQNKEKQRRIETLEKYLAD-LPTLDDVQSQSLQLQILEEKNKNLQEAL 545
++ + QKE + N + + ++D + L+ Q + ++ + E + L + +
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE-SLTEVHRRELNDVI 1044
Query: 546 IDTEKKL----EEIKK----QCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRL 597
EKKL EE+++ Q Q+KE ++ K+K + + +++ E+G+
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV-- 1102
Query: 598 PMLDAKQLQNENDNLRQQNETASKIIDSQQDE--IDRMILEIQSMQGKLSKEKLTTQKMM 655
KQ N+ Q + ++ + QDE + + +++ K KE Q+ +
Sbjct: 1103 -----KQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1157
Query: 656 EELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQL 715
EL+ +R L + TDE L E + L + L + ++L
Sbjct: 1158 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHE----KSNKSLEDKSLEFKKLSEEL 1213
Query: 716 FKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSD 775
++ C +AL + + + R +C T+ + T +S+
Sbjct: 1214 AIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSE 1273
Query: 776 VCQLRRDIDELRTTISDRYAQ 796
+ R + E + T++ + Q
Sbjct: 1274 LEAQLRQLTEEQNTLNISFQQ 1294
Score = 49.7 bits (117), Expect = 1e-05
Identities = 81/494 (16%), Positives = 196/494 (39%), Gaps = 69/494 (13%)
Query: 364 LKIKEGLLRQKEI-----VIDRQKQQITHLHERIRDNE--LRAQHAMLGHYVNCEDSYVA 416
LK KE + ++I +D+Q ++ L + D++ + + + L + + + +
Sbjct: 1469 LKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 417 SLQPQYENTSLQTPFSEESV-SHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKK 475
L+ +++ E + +++QQ + E K E++Q + ++ K+
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHK------ELVQKLQHFQELGEEKDNRVKE 1582
Query: 476 LEEKLKTRDRYISSLKKKCQKESEQ-------NKEKQRRIETLE--------KYLADLPT 520
EEK+ T + + S+K + + + ++ K K+ ++ LE LA+L
Sbjct: 1583 AEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKR 1642
Query: 521 LDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTV 580
+ + +++ Q+L + + ++ TE L E+ + Q++E ++ ++K K + ++
Sbjct: 1643 KAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQ 1702
Query: 581 QSL---------------------QQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETA 619
Q V++ E+ I + + + + + Q+ E
Sbjct: 1703 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEET 1762
Query: 620 SKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERN-----VQRLTKALLE 674
+ + +++++ + K +++ + EELE+K + Q + K +
Sbjct: 1763 VSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGK 1822
Query: 675 NQRQTDETC-SLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSIL 733
N Q + ++ D Q+ Q ++ T +++Q KE+ CL K + +
Sbjct: 1823 NNIQAKQNLENVFDDVQKTLQEKELT---------CQILEQKIKELDSCLVRQKEVHRVE 1873
Query: 734 NQRAQGKEPNLSLLLGIRSMN----CSAEETENDHSTETLTKKLSDVCQLRRDIDELRTT 789
+ K L L + N E TE + + KL + + + E +
Sbjct: 1874 MEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLA 1933
Query: 790 ISDRYAQDMGDNCI 803
++R Q +G +
Sbjct: 1934 GAEREKQKLGKEIV 1947
Score = 37.4 bits (85), Expect = 0.056
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 6/148 (4%)
Query: 443 EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNK 502
EF +LA E+E L +K+ ++ E + +L E + + LKK +K+ + +
Sbjct: 2000 EFNTQLAQKEQE---LEMTIKETINKAQEVEAELLESHQEETNQL--LKKIAEKDDDLKR 2054
Query: 503 EKQRRIETLEKYLADLPT-LDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQD 561
+R E L+ ++ + D+Q+Q +LQ ++ +E + + E++ Q
Sbjct: 2055 TAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQ 2114
Query: 562 KETQLICQKKKEKELVTTVQSLQQKVER 589
K T + K KE+E + +L+ ++++
Sbjct: 2115 KTTLISDSKLKEQEFREQIHNLEDRLKK 2142
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 67.4 bits (163), Expect = 5e-11
Identities = 107/499 (21%), Positives = 198/499 (39%), Gaps = 58/499 (11%)
Query: 300 LTEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSK 359
+ E T L G++ +DS L Q +ED R S +V T +Q +
Sbjct: 69 VAELEETRELAGQHEDDSLEL----QGLLEDERLASAQQAEVFTKQIQQLQG-------E 117
Query: 360 WESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQ 419
S+ + L +KE + +Q++ I+ A+ + H +S +ASLQ
Sbjct: 118 LRSLREEISLLEHEKESELKEIEQELHLAQAEIQSLRQAAEDSATEH-----ESDIASLQ 172
Query: 420 PQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEK 479
+ E +G++E ++AS E+ + L L S+ EE
Sbjct: 173 EDLCRMQNELEDMERI-----RGDYEMEIASLRAEMEMKSSEPSGSLGL-SDYSGLQEEL 226
Query: 480 LKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNK 539
+ R+RY L ++ + E N ++ LE T +QSQ+L + E +
Sbjct: 227 QELRERY-HFLNEEYRALQESNSSLTGQLADLESERTQRATERWLQSQTLSMTSAESQTS 285
Query: 540 NLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPM 599
+ ++ + +++ +++Q +D E Q+ K K +EL ++ LQ + E+ RL
Sbjct: 286 EMD--FLEPDPEMQLLRQQLRDAEEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRLQR 343
Query: 600 LDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELE 659
+ K QNE + + +Q +E+ + +Q E+ KM +L+
Sbjct: 344 -ELKCAQNEVLRFQTSHSV------TQNEELKSRLCTLQKKYDTSQDEQNELLKMQLQLQ 396
Query: 660 KKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEM 719
+ R ++ + L+ENQ + + C L Q+ Q K L + QL +E+
Sbjct: 397 TELRQLKVMKSTLVENQSEKELLCRL----QKLHLQHQNVTCEKEKLLERQ--QQLQEEL 450
Query: 720 SCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQL 779
C +L+ L + A KE N E D T +++ + Q
Sbjct: 451 QCHEAELQHLRDTV---ASFKESN-----------------EKDTETHAQLQEMKQLYQA 490
Query: 780 RRDIDELRTTISDRYAQDM 798
+D E + + D+ QD+
Sbjct: 491 SKDELERQKHMYDQLEQDL 509
Score = 38.1 bits (87), Expect = 0.033
Identities = 56/301 (18%), Positives = 129/301 (42%), Gaps = 51/301 (16%)
Query: 410 CEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLF 469
C+ S+V+S EE FE+ + +VL + ++ +
Sbjct: 827 CQKSFVSSCT------------DEEPAEPEDMERFEEMVV----KVLIKLQAVQAMYQIS 870
Query: 470 SEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLA---DLPTLDDVQS 526
EE +L+E++ ++ ++ K ++ +E + +E LEK +A D + ++Q+
Sbjct: 871 QEEHSQLQEQM---EKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKNEIKELQT 927
Query: 527 QSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQK 586
+ +LQ+ + + + Q L+ +++LE + CQ++ QL ++K +V +
Sbjct: 928 KLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELRQL---REKRPSVVKEARG---- 980
Query: 587 VERCLEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEID-----RMILEIQSMQ 641
+A + N+N N + + D+ + +++ ++L ++ Q
Sbjct: 981 -------------KNANKNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQ 1027
Query: 642 GK---LSKEKLTTQKMMEELEK-KERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQ 697
K L+KE+ ++M EE ++ KE ++ L+ +E S DQ + + +
Sbjct: 1028 RKLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEE 1087
Query: 698 Q 698
+
Sbjct: 1088 E 1088
Score = 33.1 bits (74), Expect = 1.1
Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 11/201 (5%)
Query: 373 QKEIVIDRQKQQITHLHERIRDNELRAQHAM--LGHYVNCEDSYVASLQPQYENTSLQTP 430
+K + K +I L ++R+ +L+ Q +M G + ++ LQ E Q
Sbjct: 910 EKPMAPQNDKNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELR-QLR 968
Query: 431 FSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFS---EEKKKLEEKL--KTRDR 485
SV +G+ K + +++ + K E +K LE L K R
Sbjct: 969 EKRPSVVKEARGKNANKNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQR 1028
Query: 486 YISSLKKKCQKESEQNKEKQRRIETLEKYLAD---LPTLDDVQSQSLQLQILEEKNKNLQ 542
+ L K+ +K+ E +EK++ E ++ D D +++S + Q E++K +
Sbjct: 1029 KLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEEE 1088
Query: 543 EALIDTEKKLEEIKKQCQDKE 563
E D+E++ ++ + E
Sbjct: 1089 EKEEDSEEEEDDADSSLESPE 1109
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 7e-11
Identities = 61/349 (17%), Positives = 170/349 (48%), Gaps = 28/349 (8%)
Query: 358 SKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVAS 417
+K + L++ E + ++ + K+++ + +L+A+ LG + S A
Sbjct: 285 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAK 341
Query: 418 LQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL- 476
LQ Q E L +++ + E+K+ E+++ + E ++++ E+++K+
Sbjct: 342 LQAQVEENELWNRLNQQQ--EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399
Query: 477 ---------EEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTL-DDVQS 526
EEK++ ++ + ++K +++ E EK+ +I LE+ + + + + +
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 527 QSLQLQILEEKNKNLQEA-LIDTEKKLEEIKKQCQDKETQLICQKKK--EKELVTTVQSL 583
+ + +I E++ + QEA + E+K+ E +++ +++E ++ Q++K E+E + +
Sbjct: 460 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519
Query: 584 QQKVERC-LEDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQG 642
Q++ E E+ IR + +++ + + + +Q E K Q++++ R ++ +
Sbjct: 520 QEQEEMWRQEEKIR----EQEEIWRQKEKIHEQEEKIRK----QEEKMWRQEEKMHDQEE 571
Query: 643 KLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQE 691
K+ +++ + E++ ++E ++ + + E + T E + + +E
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Score = 63.9 bits (154), Expect = 6e-10
Identities = 66/356 (18%), Positives = 168/356 (47%), Gaps = 40/356 (11%)
Query: 355 QDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERI--RDNELRAQHAMLGHYVNCED 412
+ +WE ++ +E +R++E I Q++++ E + ++ ++R Q M+ E+
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK---EE 424
Query: 413 SYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEE 472
+ +E EE + ++ EQ+ ++E Q E ++++ +E
Sbjct: 425 KMRRQEEMMWEK--------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 473 KK--KLEEKLKTRDRYISSLKKKCQKESEQ--------NKEKQRRIETLEKYLADLPTLD 522
K + EEK++ ++ I ++K ++ E+ +EK++ E + + + +
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 523 DVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQS 582
++ Q ++ EEK + +E + E+K+ + +++ +++E ++ Q++K +E ++
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 583 LQQKV----ERCLEDGIRLPMLDAK------QLQNENDNLRQQNE---TASKIIDSQQDE 629
++K+ E E ++ + K ++Q + + +R+Q E K I Q+++
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Query: 630 IDRMILEIQSMQGKL--SKEKLTTQ--KMMEELEKKERNVQRLTKALLENQRQTDE 681
I +Q + K+ +EK+ Q KM E+ EK R +++ + + ++Q ++
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 56.6 bits (135), Expect = 9e-08
Identities = 53/284 (18%), Positives = 135/284 (47%), Gaps = 24/284 (8%)
Query: 324 QQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIKEG--LLRQKEIVIDRQ 381
+Q++I + + + ++ RQ Q+ W KI+E +R++E + RQ
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQE-----QEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 382 KQQITHLHERIRDNELRAQHAMLGHYVNC--EDSYVASLQPQYENTSLQTPFSEESVSHS 439
+++I H E+IR+ E R + + E + + + + EE +
Sbjct: 504 EEKI-HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 440 QQG--EFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKL----------EEKLKTRDRYI 487
++ + E+K+ E++V + E ++++ E+++K+ EEK+ ++ +
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Query: 488 SSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALID 547
++K Q++ E+ + ++ +I EK + + + ++ Q +Q EEK +E + +
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQE--EKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 548 TEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL 591
E+K++E +++ + +E ++ Q+ + ++ +Q Q+ +E +
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/285 (20%), Positives = 125/285 (43%), Gaps = 39/285 (13%)
Query: 429 TPFSEESVSHSQQGEFEQKLAST---------EKEVLQLNEFLKQR-LSLFSEEKKKLEE 478
+P E+ SH Q ++L + +K LQ+ + Q + E + L
Sbjct: 167 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 226
Query: 479 KLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538
+L ++ L++ + Q K+ R IE L K L ++ ++ + L+EKN
Sbjct: 227 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSL--ELYRNTITDEELKEKN 284
Query: 539 KNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLP 598
LQE L QL+ +K E +L V+ L++K+ER
Sbjct: 285 AKLQEKL-------------------QLVESEKSEIQL--NVKELKRKLERAKL------ 317
Query: 599 MLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEEL 658
+L +QLQ E D+L ++ ++ S + +Q +E + Q + K+ +++ Q+ E++
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377
Query: 659 EKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSK 703
+++E ++ + + E + + ++ + +E + +++ + K
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 67.0 bits (162), Expect = 7e-11
Identities = 102/531 (19%), Positives = 212/531 (39%), Gaps = 80/531 (15%)
Query: 184 EKIGKAKALTSQLRTIGPSCLHDSMEML-RLEDKEINKKRSSTLDCKYKFESCSKEDFRA 242
EK +A+ S+L L + + L +L++ EI K L K ++ ++F +
Sbjct: 659 EKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTS 718
Query: 243 SSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMW--L 300
+ +D+ S+ SE + + L ++ + + I+ + + +
Sbjct: 719 QLKATEEKLLDLDALRKASSEG---KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSI 775
Query: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
T +L+ L+ N +++ S ++ ++ E +Q+L ++ ++ ++
Sbjct: 776 TRELQGRELKLTNLQENLS-------EVSQVKETLEKELQIL----KEKFAEASEEAVSV 824
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
+ ++ L QKE + + L E + D E +
Sbjct: 825 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAK---------------------- 862
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
F E+ Q + ++KL + E+++++ +L+ K+ ++L
Sbjct: 863 ----------FREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLT-------KMNDEL 905
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
+ ++R + L+ K K +E Q+ IE + T+ QSQ + EE+ K
Sbjct: 906 RLKERDVEELQLKLTKANENASFLQKSIEDM--------TVKAEQSQQEAAKKHEEEKKE 957
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL---EDGIRL 597
L+ L D EKK+E QCQ+ + + ++ E T + + Q +++ L ED ++
Sbjct: 958 LERKLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEILQNLQKTLLDTEDKLKG 1014
Query: 598 PMLDAKQLQNENDNLRQQNE--TASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMM 655
+ L E + LR+Q + A++ + +++M E L K T K+
Sbjct: 1015 AREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 1074
Query: 656 EEL----EKKERNVQRLTKA----LLENQRQTDETCSLLDQGQEPDQSRQQ 698
EL E +NV+ L K+ +ENQ+ + + Q Q QQ
Sbjct: 1075 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQ 1125
Score = 66.2 bits (160), Expect = 1e-10
Identities = 124/671 (18%), Positives = 272/671 (40%), Gaps = 80/671 (11%)
Query: 190 KALTSQLRTIGPSCLHDSMEMLRLEDKEINKKRSSTLDCKYKFESCSKEDFRASS----- 244
+A QLRT+ + + +E+L ++E K++ L + + ES +K D ++
Sbjct: 407 EAKMDQLRTMVEAADREKVELLNQLEEE--KRKVEDLQFRVEEESITKGDLEVATVSEKS 464
Query: 245 ----------------STLRRQ--------PVDMTYSALPESKPIMTSSEAF--EPPKYL 278
+ LRR+ VDM+ S L E + E + + +
Sbjct: 465 RIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREI 524
Query: 279 MLGQQAVGG--VPIQPSVRTQMWLTEQLRT------NPLEGRNTEDSYSLAPWQQQQIED 330
++ G Q ++ TE+L + LE N E+S +A W+ + +E
Sbjct: 525 TSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSK-LET 583
Query: 331 FRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIK--------EGLLRQKEIVIDRQK 382
+ M+ L S + +F++ ++ ++ E L Q++
Sbjct: 584 AIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHA 643
Query: 383 QQITHLHERI------RDNELRAQHAMLG-----HYVNCEDSYVASLQPQYENTSLQTPF 431
+++ L ++ ++N L A + L H V ED+ + + + L+
Sbjct: 644 KEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQ 703
Query: 432 SEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLK 491
++ + F +L +TE+++L L+ L++ S E KKL ++L+ ++ I L+
Sbjct: 704 AKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEGKSEMKKLRQQLEAAEKQIKHLE 762
Query: 492 KKCQKESEQNKEKQRRIETLEKYLADLP-TLDDV----QSQSLQLQILEEKNKNLQEALI 546
+ ES + R ++ E L +L L +V ++ +LQIL+EK E +
Sbjct: 763 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAV 822
Query: 547 DTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQ-L 605
++ ++E + KE Q ++L + ++ K +D ++ AK+ L
Sbjct: 823 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFRE--KDEREEQLIKAKEKL 880
Query: 606 QNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELE----KK 661
+N+ + + + S + DE+ +++ +Q KL+K + + +E K
Sbjct: 881 ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 940
Query: 662 ERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQLFKEMSC 721
E++ Q K E +++ + S L++ E ++ Q + ++ ++ + K
Sbjct: 941 EQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEI 997
Query: 722 CLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSTETLTKKLSDVCQLRR 781
K L ++ +E N LL + + A++ + + +T + + Q+ +
Sbjct: 998 LQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK---AAQTAEDAMQIMEQMTK 1054
Query: 782 DIDELRTTISD 792
+ E ++ D
Sbjct: 1055 EKTETLASLED 1065
Score = 36.6 bits (83), Expect = 0.095
Identities = 47/228 (20%), Positives = 100/228 (43%), Gaps = 9/228 (3%)
Query: 423 ENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFL-KQRLSLFSEEKKKLEEKLK 481
EN ++ E + Q+L++ ++E ++L E L + R + S +K LEE+
Sbjct: 1101 ENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK--LEEERS 1158
Query: 482 TRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNL 541
+ + +KK+ K + E++ ++ + L T D + + L+ ++ + +N
Sbjct: 1159 VLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENA 1218
Query: 542 Q-EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTT----VQSLQQKVERCLEDGIR 596
++L + LE K + + K L Q K+ K +++ + + ER E I
Sbjct: 1219 SAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQID 1278
Query: 597 LPMLDAKQLQNENDNLRQQNETASK-IIDSQQDEIDRMILEIQSMQGK 643
LQ +N +L+ + E S+ ++ D+++ + Q Q K
Sbjct: 1279 FLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSK 1326
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 67.0 bits (162), Expect = 7e-11
Identities = 102/531 (19%), Positives = 212/531 (39%), Gaps = 80/531 (15%)
Query: 184 EKIGKAKALTSQLRTIGPSCLHDSMEML-RLEDKEINKKRSSTLDCKYKFESCSKEDFRA 242
EK +A+ S+L L + + L +L++ EI K L K ++ ++F +
Sbjct: 694 EKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTS 753
Query: 243 SSSTLRRQPVDMTYSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQMW--L 300
+ +D+ S+ SE + + L ++ + + I+ + + +
Sbjct: 754 QLKATEEKLLDLDALRKASSEG---KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSI 810
Query: 301 TEQLRTNPLEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKW 360
T +L+ L+ N +++ S ++ ++ E +Q+L ++ ++ ++
Sbjct: 811 TRELQGRELKLTNLQENLS-------EVSQVKETLEKELQIL----KEKFAEASEEAVSV 859
Query: 361 ESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCEDSYVASLQP 420
+ ++ L QKE + + L E + D E +
Sbjct: 860 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAK---------------------- 897
Query: 421 QYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKL 480
F E+ Q + ++KL + E+++++ +L+ K+ ++L
Sbjct: 898 ----------FREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLT-------KMNDEL 940
Query: 481 KTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKN 540
+ ++R + L+ K K +E Q+ IE + T+ QSQ + EE+ K
Sbjct: 941 RLKERDVEELQLKLTKANENASFLQKSIEDM--------TVKAEQSQQEAAKKHEEEKKE 992
Query: 541 LQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCL---EDGIRL 597
L+ L D EKK+E QCQ+ + + ++ E T + + Q +++ L ED ++
Sbjct: 993 LERKLSDLEKKMETSHNQCQELKAR---YERATSETKTKHEEILQNLQKTLLDTEDKLKG 1049
Query: 598 PMLDAKQLQNENDNLRQQNE--TASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMM 655
+ L E + LR+Q + A++ + +++M E L K T K+
Sbjct: 1050 AREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 1109
Query: 656 EEL----EKKERNVQRLTKA----LLENQRQTDETCSLLDQGQEPDQSRQQ 698
EL E +NV+ L K+ +ENQ+ + + Q Q QQ
Sbjct: 1110 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQ 1160
Score = 65.9 bits (159), Expect = 1e-10
Identities = 95/513 (18%), Positives = 215/513 (41%), Gaps = 39/513 (7%)
Query: 309 LEGRNTEDSYSLAPWQQQQIEDFRQGSETPMQVLTGSSRQSYSPGYQDFSKWESMLKIK- 367
LE N E+S +A W+ + +E + M+ L S + +F++ ++ ++
Sbjct: 598 LEHANKENSDVIALWKSK-LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMR 656
Query: 368 -------EGLLRQKEIVIDRQKQQITHLHERI------RDNELRAQHAMLG-----HYVN 409
E L Q++ +++ L ++ ++N L A + L H V
Sbjct: 657 LDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 716
Query: 410 CEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLF 469
ED+ + + + L+ ++ + F +L +TE+++L L+ L++ S
Sbjct: 717 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEG 775
Query: 470 SEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLP-TLDDV---- 524
E KKL ++L+ ++ I L+ + ES + R ++ E L +L L +V
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 835
Query: 525 QSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQ 584
++ +LQIL+EK E + ++ ++E + KE Q ++L + ++
Sbjct: 836 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 895
Query: 585 QKVERCLEDGIRLPMLDAKQ-LQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGK 643
K +D ++ AK+ L+N+ + + + S + DE+ +++ +Q K
Sbjct: 896 AKFRE--KDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLK 953
Query: 644 LSKEKLTTQKMMEELE----KKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQT 699
L+K + + +E K E++ Q K E +++ + S L++ E ++ Q
Sbjct: 954 LTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 1013
Query: 700 VLSKRPLFDLTVIDQLFKEMSCCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEE 759
+ ++ ++ + K K L ++ +E N LL + + A++
Sbjct: 1014 LKAR---YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADK 1070
Query: 760 TENDHSTETLTKKLSDVCQLRRDIDELRTTISD 792
+ + +T + + Q+ ++ E ++ D
Sbjct: 1071 AK---AAQTAEDAMQIMEQMTKEKTETLASLED 1100
Score = 44.3 bits (103), Expect = 5e-04
Identities = 55/254 (21%), Positives = 114/254 (44%), Gaps = 21/254 (8%)
Query: 524 VQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSL 583
V S+ + +L E + + T E +K++ Q E QL+ ++ E+ V S
Sbjct: 326 VSSRPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIE-QLLAERDLERAEVAKATSH 384
Query: 584 QQKVERCL---EDGIRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSM 640
++E+ L DG +L+ L+ + D LR E A + ++++ +++ +
Sbjct: 385 VGEIEQELALARDGHDQHVLE---LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDL 441
Query: 641 QGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTV 700
Q ++ +E +T + + + + ++ L ++LL + + D+ +E + +R TV
Sbjct: 442 QFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKL------QRELEDTRVATV 495
Query: 701 LSKRPLFDLTVIDQLFKEMSCCLFDLKALCSIL--NQRAQGKEPNLSLLLGIRSMNCSAE 758
K + +L K+++ + ++ L L N+ A + +LSLL I S+ E
Sbjct: 496 SEKSRIMELE------KDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLE 549
Query: 759 ETENDHSTETLTKK 772
T DH E + K
Sbjct: 550 VTRTDHQREITSLK 563
Score = 36.6 bits (83), Expect = 0.095
Identities = 47/228 (20%), Positives = 100/228 (43%), Gaps = 9/228 (3%)
Query: 423 ENTSLQTPFSEESVSHSQQGEFEQKLASTEKEVLQLNEFL-KQRLSLFSEEKKKLEEKLK 481
EN ++ E + Q+L++ ++E ++L E L + R + S +K LEE+
Sbjct: 1136 ENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK--LEEERS 1193
Query: 482 TRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNL 541
+ + +KK+ K + E++ ++ + L T D + + L+ ++ + +N
Sbjct: 1194 VLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENA 1253
Query: 542 Q-EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTT----VQSLQQKVERCLEDGIR 596
++L + LE K + + K L Q K+ K +++ + + ER E I
Sbjct: 1254 SAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQID 1313
Query: 597 LPMLDAKQLQNENDNLRQQNETASK-IIDSQQDEIDRMILEIQSMQGK 643
LQ +N +L+ + E S+ ++ D+++ + Q Q K
Sbjct: 1314 FLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSK 1361
>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
Length = 541
Score = 66.6 bits (161), Expect = 9e-11
Identities = 74/333 (22%), Positives = 150/333 (45%), Gaps = 40/333 (12%)
Query: 432 SEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSL-FSEEKKKLEEKLKTRDRYISSL 490
S+ V+H + G Q++ EK +KQ +++ + +E KKL E+L R L
Sbjct: 66 SQLDVTHKEVGMLHQQVEEHEK--------IKQEMTMEYKQELKKLHEELCILKRSYEKL 117
Query: 491 KKKCQKE----SEQNKEKQRRIETLEKYLADL--PTLD----------DVQSQSLQLQIL 534
+KK +E ++ ++E + IE L + + +LD V S Q + L
Sbjct: 118 QKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKAL 177
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
E+++ +Q L++ ++KLE ++ Q + L + ++ + + + +++ + D
Sbjct: 178 AEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDL 237
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKM 654
+ M ++ Q + + LR+ + K++++ Q+E + +QS + + + ++ +K+
Sbjct: 238 VGTSMTVLQEQQQKEEKLRE----SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKL 293
Query: 655 MEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQ 714
E++ K N Q +A+ + E QG Q +VLS+ F T D
Sbjct: 294 QEKV--KATNTQHAVEAIRPREESLAEK-KYTSQG----QGDLDSVLSQLN-FTHTSEDL 345
Query: 715 LFKEMSC---CLFDLKALCSILNQRAQGKEPNL 744
L E++C L + A C L+Q K L
Sbjct: 346 LQAEVTCLEGSLESVSATCKQLSQELMEKYEEL 378
>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
Length = 703
Score = 66.6 bits (161), Expect = 9e-11
Identities = 74/333 (22%), Positives = 150/333 (45%), Gaps = 40/333 (12%)
Query: 432 SEESVSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSL-FSEEKKKLEEKLKTRDRYISSL 490
S+ V+H + G Q++ EK +KQ +++ + +E KKL E+L R L
Sbjct: 66 SQLDVTHKEVGMLHQQVEEHEK--------IKQEMTMEYKQELKKLHEELCILKRSYEKL 117
Query: 491 KKKCQKE----SEQNKEKQRRIETLEKYLADL--PTLD----------DVQSQSLQLQIL 534
+KK +E ++ ++E + IE L + + +LD V S Q + L
Sbjct: 118 QKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKAL 177
Query: 535 EEKNKNLQEALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDG 594
E+++ +Q L++ ++KLE ++ Q + L + ++ + + + +++ + D
Sbjct: 178 AEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDL 237
Query: 595 IRLPMLDAKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKM 654
+ M ++ Q + + LR+ + K++++ Q+E + +QS + + + ++ +K+
Sbjct: 238 VGTSMTVLQEQQQKEEKLRE----SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKL 293
Query: 655 MEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVIDQ 714
E++ K N Q +A+ + E QG Q +VLS+ F T D
Sbjct: 294 QEKV--KATNTQHAVEAIRPREESLAEK-KYTSQG----QGDLDSVLSQLN-FTHTSEDL 345
Query: 715 LFKEMSC---CLFDLKALCSILNQRAQGKEPNL 744
L E++C L + A C L+Q K L
Sbjct: 346 LQAEVTCLEGSLESVSATCKQLSQELMEKYEEL 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,612,849
Number of Sequences: 37866
Number of extensions: 1446799
Number of successful extensions: 14697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 318
Number of HSP's successfully gapped in prelim test: 1164
Number of HSP's that attempted gapping in prelim test: 7065
Number of HSP's gapped (non-prelim): 4515
length of query: 805
length of database: 18,247,518
effective HSP length: 110
effective length of query: 695
effective length of database: 14,082,258
effective search space: 9787169310
effective search space used: 9787169310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.