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Search of human proteins with 149588599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149588599 membrane-spanning 4-domains, subfamily A, member
15 isoform 1 [Homo sapiens]
(240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 483 e-137
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ... 294 4e-80
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 126 2e-29
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 125 2e-29
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ... 85 6e-17
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ... 85 6e-17
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ... 85 6e-17
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 82 4e-16
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 82 4e-16
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [... 79 5e-15
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [... 79 5e-15
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 3e-13
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 4e-13
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 4e-13
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 69 4e-12
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 69 4e-12
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ... 68 8e-12
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 67 2e-11
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 63 2e-10
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ... 63 2e-10
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ... 63 2e-10
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 57 1e-08
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10... 56 3e-08
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i... 52 4e-07
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i... 52 4e-07
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 45 6e-05
gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i... 39 0.004
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 36 0.034
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 36 0.034
gi|146134388 YLP motif containing 1 [Homo sapiens] 35 0.044
>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
isoform 1 [Homo sapiens]
Length = 240
Score = 483 bits (1242), Expect = e-137
Identities = 240/240 (100%), Positives = 240/240 (100%)
Query: 1 MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDL 60
MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDL
Sbjct: 1 MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDL 60
Query: 61 RPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIIS 120
RPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIIS
Sbjct: 61 RPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIIS 120
Query: 121 GSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFT 180
GSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFT
Sbjct: 121 GSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFT 180
Query: 181 VLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV 240
VLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV
Sbjct: 181 VLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV 240
>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
isoform 2 [Homo sapiens]
Length = 147
Score = 294 bits (753), Expect = 4e-80
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 94 MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 153
MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG
Sbjct: 1 MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 60
Query: 154 TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 213
TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF
Sbjct: 61 TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 120
Query: 214 SADFNIPSPAASAPPAYDNVAYAQGVV 240
SADFNIPSPAASAPPAYDNVAYAQGVV
Sbjct: 121 SADFNIPSPAASAPPAYDNVAYAQGVV 147
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 126 bits (316), Expect = 2e-29
Identities = 91/265 (34%), Positives = 131/265 (49%), Gaps = 39/265 (14%)
Query: 1 MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPR------- 53
MS+ P S+ PN PP + + QP G + E GAQ +
Sbjct: 2 MSSKPTSHAEVNETIPNPY----PPGSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSP 57
Query: 54 ----ATQP---------PDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHV 100
++QP P + E K LG +QI++GL+H+GFG VL ++
Sbjct: 58 GIFASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFR 117
Query: 101 GIF-----FIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTA 155
+ + GG PFWGG FIISGSLSV+A K + CLV+ SLG NI+S + AF G
Sbjct: 118 EVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVI 177
Query: 156 ILLMDF---GVTNRDV-----DRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVI 207
+LL+D GV +D +G A L IF++LEFF A HF QA + + V+
Sbjct: 178 LLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQA-NTTTNMSVL 236
Query: 208 FLPNAFSADFNIPSPAASAPPAYDN 232
+PN + ++ P+ ++SAPP +N
Sbjct: 237 VIPNMYESNPVTPA-SSSAPPRCNN 260
>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
[Homo sapiens]
Length = 250
Score = 125 bits (315), Expect = 2e-29
Identities = 85/245 (34%), Positives = 118/245 (48%), Gaps = 20/245 (8%)
Query: 2 SAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLR 61
SA P +N V VV P N G P I+ P Q P P + +
Sbjct: 6 SAVPVANSVLVVAPHN---GYPVTPGIMSHVPLYPNSQPQVHLVP--GNPPSLVSNVNGQ 60
Query: 62 PVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISG 121
PV+ L E K LG +QI+IGL H+G GS++ V G GG PFWGG FIISG
Sbjct: 61 PVQKALK-EGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISG 119
Query: 122 SLSVAAEKN-HTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYL------- 173
SLSVAAE ++ CL+ SLG NI+S + + G + + D + + Y
Sbjct: 120 SLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVN 179
Query: 174 ------AVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAP 227
VL +F +LEF A + HFGCQ + Q+S + PN ++A+ I ++P
Sbjct: 180 PGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSP 239
Query: 228 PAYDN 232
P+Y +
Sbjct: 240 PSYSS 244
>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 84.7 bits (208), Expect = 6e-17
Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 32/243 (13%)
Query: 7 SNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPP--LGAQTPRAT--------- 55
+N V +I P+N + P + + QP + + P + T RA
Sbjct: 65 ANSVPGIIAPDNVHVIQPSNPVASGNHLQPSEVTTYPISPKVIHCDTGRANLQNLLVVNQ 124
Query: 56 ------QPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGV 109
Q + + G + +QILIGL H+ S + V + + ++ G
Sbjct: 125 NSAAGVQSQPIGYQRQYPVGTASLQTAIQILIGLTHIF--SAINPVLYYYPFVTWLSG-Y 181
Query: 110 PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV-----T 164
P WGG +I+SGSLSV A K+ + C+V SS+ NI+S + AFAG I++ D +
Sbjct: 182 PLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVTTY 241
Query: 165 NRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAA 224
++ V G L F +LEF + HFGCQA + V +P FS FN P+
Sbjct: 242 SKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PANTT 294
Query: 225 SAP 227
++P
Sbjct: 295 TSP 297
>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 84.7 bits (208), Expect = 6e-17
Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 32/243 (13%)
Query: 7 SNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPP--LGAQTPRAT--------- 55
+N V +I P+N + P + + QP + + P + T RA
Sbjct: 65 ANSVPGIIAPDNVHVIQPSNPVASGNHLQPSEVTTYPISPKVIHCDTGRANLQNLLVVNQ 124
Query: 56 ------QPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGV 109
Q + + G + +QILIGL H+ S + V + + ++ G
Sbjct: 125 NSAAGVQSQPIGYQRQYPVGTASLQTAIQILIGLTHIF--SAINPVLYYYPFVTWLSG-Y 181
Query: 110 PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV-----T 164
P WGG +I+SGSLSV A K+ + C+V SS+ NI+S + AFAG I++ D +
Sbjct: 182 PLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVTTY 241
Query: 165 NRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAA 224
++ V G L F +LEF + HFGCQA + V +P FS FN P+
Sbjct: 242 SKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PANTT 294
Query: 225 SAP 227
++P
Sbjct: 295 TSP 297
>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 84.7 bits (208), Expect = 6e-17
Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 32/243 (13%)
Query: 7 SNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPP--LGAQTPRAT--------- 55
+N V +I P+N + P + + QP + + P + T RA
Sbjct: 65 ANSVPGIIAPDNVHVIQPSNPVASGNHLQPSEVTTYPISPKVIHCDTGRANLQNLLVVNQ 124
Query: 56 ------QPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGV 109
Q + + G + +QILIGL H+ S + V + + ++ G
Sbjct: 125 NSAAGVQSQPIGYQRQYPVGTASLQTAIQILIGLTHIF--SAINPVLYYYPFVTWLSG-Y 181
Query: 110 PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV-----T 164
P WGG +I+SGSLSV A K+ + C+V SS+ NI+S + AFAG I++ D +
Sbjct: 182 PLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVTTY 241
Query: 165 NRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAA 224
++ V G L F +LEF + HFGCQA + V +P FS FN P+
Sbjct: 242 SKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PANTT 294
Query: 225 SAP 227
++P
Sbjct: 295 TSP 297
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 82.0 bits (201), Expect = 4e-16
Identities = 64/182 (35%), Positives = 87/182 (47%), Gaps = 25/182 (13%)
Query: 64 ETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGI--FFIEGGVPFWGGACFIISG 121
E FL GEPKVLG VQIL L+ L G ++ + G + G WG FIISG
Sbjct: 37 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISG 96
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT-------------NRDV 168
SLS+AA T LVR SLG NI S + A +G IL+ F + N +
Sbjct: 97 SLSIAAGIRTTKGLVRGSLGMNITSSVLAASG--ILINTFSLAFYSFHHPYCNYYGNSNN 154
Query: 169 DRGYLAVL-------TIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLP-NAFSADFNIP 220
G +++L + +VLEF AV FGC+ + V+ LP ++ A+ P
Sbjct: 155 CHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASP 214
Query: 221 SP 222
+P
Sbjct: 215 TP 216
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 82.0 bits (201), Expect = 4e-16
Identities = 64/182 (35%), Positives = 87/182 (47%), Gaps = 25/182 (13%)
Query: 64 ETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGI--FFIEGGVPFWGGACFIISG 121
E FL GEPKVLG VQIL L+ L G ++ + G + G WG FIISG
Sbjct: 56 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISG 115
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT-------------NRDV 168
SLS+AA T LVR SLG NI S + A +G IL+ F + N +
Sbjct: 116 SLSIAAGIRTTKGLVRGSLGMNITSSVLAASG--ILINTFSLAFYSFHHPYCNYYGNSNN 173
Query: 169 DRGYLAVL-------TIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLP-NAFSADFNIP 220
G +++L + +VLEF AV FGC+ + V+ LP ++ A+ P
Sbjct: 174 CHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASP 233
Query: 221 SP 222
+P
Sbjct: 234 TP 235
>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 78.6 bits (192), Expect = 5e-15
Identities = 42/99 (42%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
Query: 62 PVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISG 121
P ++F E K LG VQI+ GL H+ G LLM+ G + P WGG +IISG
Sbjct: 40 PTQSFFMRESKTLGAVQIMNGLFHIALGG-LLMIPAGIYAPICVTVWYPLWGGIMYIISG 98
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 160
SL A EKN CLV+ + N LS+ AA +G + +MD
Sbjct: 99 SLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMD 137
>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 78.6 bits (192), Expect = 5e-15
Identities = 42/99 (42%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
Query: 62 PVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISG 121
P ++F E K LG VQI+ GL H+ G LLM+ G + P WGG +IISG
Sbjct: 40 PTQSFFMRESKTLGAVQIMNGLFHIALGG-LLMIPAGIYAPICVTVWYPLWGGIMYIISG 98
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 160
SL A EKN CLV+ + N LS+ AA +G + +MD
Sbjct: 99 SLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMD 137
>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 72.4 bits (176), Expect = 3e-13
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 21/180 (11%)
Query: 64 ETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGI--FFIEGGVPFWGGACFIISG 121
E F +PKVLG V+ILI L+ L G +++ V F+ WG FIIS
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD-------FGVTNRD------- 167
SLSVAA T LV SLG NI S + A +G I + + N D
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 168 ----VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLP-NAFSADFNIPSP 222
+ G ++ + +VLEF AV FGC+ + S V+ P N+ A+ P+P
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVALSAFGCKVLCCSPSEVVLITPSNSHMAEIASPTP 239
>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 1 [Homo sapiens]
Length = 243
Score = 72.0 bits (175), Expect = 4e-13
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 21/180 (11%)
Query: 64 ETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGI--FFIEGGVPFWGGACFIISG 121
E F +PKVLG V+ILI L+ L G +++ V F+ WG FIIS
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD-------FGVTNRD------- 167
SLSVAA T LV SLG NI S + A +G I + + N D
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 168 ----VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLP-NAFSADFNIPSP 222
+ G ++ + +VLEF AV FGC+ + S V+ P N+ A+ P+P
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCKVLCCSPSEVVLITPSNSHMAEIASPTP 239
>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 72.0 bits (175), Expect = 4e-13
Identities = 59/180 (32%), Positives = 81/180 (45%), Gaps = 21/180 (11%)
Query: 64 ETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGI--FFIEGGVPFWGGACFIISG 121
E F +PKVLG V+ILI L+ L G +++ V F+ WG FIIS
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 122 SLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD-------FGVTNRD------- 167
SLSVAA T LV SLG NI S + A +G I + + N D
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 168 ----VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLP-NAFSADFNIPSP 222
+ G ++ + +VLEF AV FGC+ + S V+ P N+ A+ P+P
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCKVLCCSPSEVVLITPSNSHMAEIASPTP 239
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 68.9 bits (167), Expect = 4e-12
Identities = 50/143 (34%), Positives = 68/143 (47%), Gaps = 15/143 (10%)
Query: 29 LPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLT---GEPKVLGTVQILIGLIH 85
LP P E P + R + P+ T+LT E + LG QIL +I
Sbjct: 13 LPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMIC 72
Query: 86 LGFGSVLLMVRRGHVGIFFIEG--------GVPFWGGACFIISGSLSVAAEKNHTSCLVR 137
L FG+V+ V + I IEG G PFWG F ISG LS+ +E+ + + LVR
Sbjct: 73 LCFGTVVCSV----LDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVR 128
Query: 138 SSLGTNILSVMAAFAGTAILLMD 160
SLG N S +A G IL+++
Sbjct: 129 GSLGANTASSIAGGTGITILIIN 151
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 68.9 bits (167), Expect = 4e-12
Identities = 50/143 (34%), Positives = 68/143 (47%), Gaps = 15/143 (10%)
Query: 29 LPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLT---GEPKVLGTVQILIGLIH 85
LP P E P + R + P+ T+LT E + LG QIL +I
Sbjct: 13 LPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMIC 72
Query: 86 LGFGSVLLMVRRGHVGIFFIEG--------GVPFWGGACFIISGSLSVAAEKNHTSCLVR 137
L FG+V+ V + I IEG G PFWG F ISG LS+ +E+ + + LVR
Sbjct: 73 LCFGTVVCSV----LDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVR 128
Query: 138 SSLGTNILSVMAAFAGTAILLMD 160
SLG N S +A G IL+++
Sbjct: 129 GSLGANTASSIAGGTGITILIIN 151
>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
isoform 1 [Homo sapiens]
Length = 248
Score = 67.8 bits (164), Expect = 8e-12
Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 44/230 (19%)
Query: 31 TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90
T + P ++ F + A+ P T ++ L E KV+GT+QIL G++ L G
Sbjct: 10 TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
Query: 91 VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146
+L V + PF G FIISGSLS+A EK T LV SSL +ILS
Sbjct: 65 ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
Query: 147 VMAAFAGTAILLMDFGVTNR-----DVDR------------------------------G 171
++A G IL + N ++D+ G
Sbjct: 125 ALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAG 184
Query: 172 YLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPS 221
L+++ I T+LEF AV+ + ++ V+FLP+++ + + S
Sbjct: 185 TLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSS 234
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 66.6 bits (161), Expect = 2e-11
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 29/190 (15%)
Query: 30 PTSMCQPPGIM--QFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLG 87
P + PP I ++E L A T +TQ P ++ + K+LGT+QIL G++
Sbjct: 9 PVFLVFPPEITASEYESTELSATT-FSTQSP----LQKLFARKMKILGTIQILFGIMTFS 63
Query: 88 FGSVLL--MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNIL 145
FG + L +++ F G PFWG FI SG+ +A ++ T L+ S N L
Sbjct: 64 FGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFL 123
Query: 146 SVMAAFAGTAILLMDFG-VTNRDVDRGY-----------------LAVLTIFTVLEFFTA 187
S + A AG I+L+ FG + +++ GY L L F+++E F +
Sbjct: 124 SALGAIAG--IILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFIS 181
Query: 188 VIAMHFGCQA 197
+ GC +
Sbjct: 182 LPFSILGCHS 191
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 63.2 bits (152), Expect = 2e-10
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 25/133 (18%)
Query: 49 AQTPRATQPPDLRPVET---------------FLTGEPKVLGTVQILIGLIHLGFGSVLL 93
+Q RAT ++P ET FL GEP+VLG QIL+ LI +GFG++
Sbjct: 5 SQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA 64
Query: 94 MVRRGHVGI-----FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVM 148
+ ++G + G PFWG FI++G L+V +K + L + G N++S +
Sbjct: 65 L---NYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSL 119
Query: 149 AAFAGTAILLMDF 161
A G ++ +
Sbjct: 120 VAITGITFTILSY 132
>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
isoform 2 [Homo sapiens]
Length = 225
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 9/131 (6%)
Query: 31 TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90
T + P ++ F + A+ P T ++ L E KV+GT+QIL G++ L G
Sbjct: 10 TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
Query: 91 VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146
+L V + PF G FIISGSLS+A EK T LV SSL +ILS
Sbjct: 65 ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
Query: 147 VMAAFAGTAIL 157
++A G IL
Sbjct: 125 ALSALVGFIIL 135
>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
isoform 3 [Homo sapiens]
Length = 178
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 9/131 (6%)
Query: 31 TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90
T + P ++ F + A+ P T ++ L E KV+GT+QIL G++ L G
Sbjct: 10 TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
Query: 91 VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146
+L V + PF G FIISGSLS+A EK T LV SSL +ILS
Sbjct: 65 ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
Query: 147 VMAAFAGTAIL 157
++A G IL
Sbjct: 125 ALSALVGFIIL 135
>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
isoform a [Homo sapiens]
Length = 214
Score = 57.4 bits (137), Expect = 1e-08
Identities = 48/181 (26%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 56 QPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVR-----RGHVGIFFIEGGVP 110
QP D P + + +VLG +QIL + L G L ++ + H F G P
Sbjct: 35 QPIDGSP--DYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYP 92
Query: 111 FWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNR---- 166
WG F SG+LSV A T +++S G NI S A GTA L ++ V +
Sbjct: 93 IWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRS 152
Query: 167 ---------------DVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPN 211
+ G +++L I T+LE + + C A + + PN
Sbjct: 153 CHSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPN 212
Query: 212 A 212
+
Sbjct: 213 S 213
>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
[Homo sapiens]
Length = 267
Score = 55.8 bits (133), Expect = 3e-08
Identities = 49/180 (27%), Positives = 79/180 (43%), Gaps = 26/180 (14%)
Query: 72 KVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNH 131
K LG I I L+HL FG L + + ++ + ++ PFWG A F+ISG L++ +
Sbjct: 58 KELGAFHITIALLHLVFGGYLASIVK-NLHLVVLKSWYPFWGAASFLISGILAITMKTFS 116
Query: 132 TSCLVRSSLGTNILSVMAAFAGTAILLMD--------------FGVTNRDVDRGYLAVLT 177
+ L L TN++S+ +G ++ D + + + R LA+L
Sbjct: 117 KTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALL- 175
Query: 178 IFTVLEFF----TAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNV 233
FTVLE F TAV A C + + +PN ++ PP+Y +V
Sbjct: 176 CFTVLELFLPVPTAVTAWRGDCP---SAKNDDACLVPN---TPLHLKGLPVEPPPSYQSV 229
>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 52.4 bits (124), Expect = 4e-07
Identities = 41/120 (34%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 46 PLGAQTPRATQPPDLRPVETFLTG----EPKVLGTVQILIGLIHLGFGSVLLMVRR-GHV 100
P G P+ +P + E +L E VLGTVQIL L+ G++L+ H
Sbjct: 16 PKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHF 75
Query: 101 GIFF---IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 157
+ G PF G CF I+GSLS+ + K T SSL +N +S + A AG +L
Sbjct: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135
>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 52.4 bits (124), Expect = 4e-07
Identities = 41/120 (34%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 46 PLGAQTPRATQPPDLRPVETFLTG----EPKVLGTVQILIGLIHLGFGSVLLMVRR-GHV 100
P G P+ +P + E +L E VLGTVQIL L+ G++L+ H
Sbjct: 16 PKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHF 75
Query: 101 GIFF---IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 157
+ G PF G CF I+GSLS+ + K T SSL +N +S + A AG +L
Sbjct: 76 NPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135
>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
isoform 2 [Homo sapiens]
Length = 662
Score = 45.1 bits (105), Expect = 6e-05
Identities = 34/133 (25%), Positives = 55/133 (41%), Gaps = 42/133 (31%)
Query: 49 AQTPRATQPPDLRPVET---------------FLTGEPKVLGTVQILIGLIHLGFGSVLL 93
+Q RAT ++P ET FL GEP+VLG QIL+ LI +GFG++
Sbjct: 5 SQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA 64
Query: 94 MVRRGHVGI-----FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVM 148
+ ++G + G PFWG + + + G N++S +
Sbjct: 65 L---NYIGFSQRLPLVVLTGYPFWG-------------------ALIGQGVTGMNVISSL 102
Query: 149 AAFAGTAILLMDF 161
A G ++ +
Sbjct: 103 VAITGITFTILSY 115
>gi|73486653 membrane-spanning 4-domains, subfamily A, member 3
isoform b [Homo sapiens]
Length = 168
Score = 38.9 bits (89), Expect = 0.004
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 19/115 (16%)
Query: 117 FIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNR---------- 166
F SG+LSV A T +++S G NI S A GTA L ++ V +
Sbjct: 53 FCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSE 112
Query: 167 ---------DVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNA 212
+ G +++L I T+LE + + C A + + PN+
Sbjct: 113 SPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNS 167
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 35.8 bits (81), Expect = 0.034
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
Query: 15 PPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTG 69
PP GL P P+++P + + P +Q E A P+AT P P ++FL G
Sbjct: 392 PPTTLLGLIPAPSMVPATDTKAPPTLQAET----ATKPQATSAPSPAPKQSFLFG 442
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 35.8 bits (81), Expect = 0.034
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
Query: 15 PPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTG 69
PP GL P P+++P + + P +Q E A P+AT P P ++FL G
Sbjct: 392 PPTTLLGLIPAPSMVPATDTKAPPTLQAET----ATKPQATSAPSPAPKQSFLFG 442
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 35.4 bits (80), Expect = 0.044
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 1 MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQ--PPGIMQFEEPPLGAQTPRATQPP 58
M + +S G V+PP + S PPP + P S+ PP +M PPL + TP PP
Sbjct: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPL--PPLSSATPPPGIPP 635
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,094,861
Number of Sequences: 37866
Number of extensions: 511695
Number of successful extensions: 3033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 2771
Number of HSP's gapped (non-prelim): 304
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.