Guide to the Human Genome
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Search of human proteins with 14917111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14917111 adaptor-related protein complex 4, mu 1 subunit
[Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom...   899   0.0  
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...   189   4e-48
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof...   183   2e-46
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof...   183   3e-46
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...   182   5e-46
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...   180   2e-45
gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo...   111   2e-24
gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Hom...   111   2e-24
gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Ho...   104   1e-22
gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo...   104   1e-22
gi|11863154 archain isoform 1 [Homo sapiens]                           42   0.001
gi|26787993 stonin 1 [Homo sapiens]                                    40   0.003
gi|29553944 STON1-GTF2A1L protein [Homo sapiens]                       40   0.003
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H...    39   0.013
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H...    38   0.017
gi|21361863 stonin 2 [Homo sapiens]                                    38   0.022
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [...    35   0.11 
gi|13994335 Mix-like homeobox protein 1 [Homo sapiens]                 34   0.24 
gi|8659574 transcription factor E3 [Homo sapiens]                      34   0.31 
gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens]    32   1.5  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    31   2.6  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    31   2.6  
gi|110227615 echinoderm microtubule associated protein like 3 [H...    31   2.6  
gi|239752280 PREDICTED: similar to family with sequence similari...    30   3.4  
gi|114431236 zinc finger protein 462 [Homo sapiens]                    30   3.4  
gi|210032463 family with sequence similarity 48, member B2 [Homo...    30   3.4  
gi|190014615 hypothetical protein LOC157983 [Homo sapiens]             30   3.4  
gi|214010212 archain isoform 2 [Homo sapiens]                          30   4.5  
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    30   4.5  
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              30   5.9  

>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
           sapiens]
          Length = 453

 Score =  899 bits (2323), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR 60
           MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR
Sbjct: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR 60

Query: 61  HSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYG 120
           HSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYG
Sbjct: 61  HSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYG 120

Query: 121 YVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD 180
           YVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD
Sbjct: 121 YVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD 180

Query: 181 QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSE 240
           QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSE
Sbjct: 181 QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSE 240

Query: 241 LRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFP 300
           LRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFP
Sbjct: 241 LRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFP 300

Query: 301 SVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGA 360
           SVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGA
Sbjct: 301 SVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGA 360

Query: 361 LRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQ 420
           LRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQ
Sbjct: 361 LRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQ 420

Query: 421 VRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI 453
           VRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI
Sbjct: 421 VRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI 453


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score =  189 bits (480), Expect = 4e-48
 Identities = 126/455 (27%), Positives = 224/455 (49%), Gaps = 42/455 (9%)

Query: 3   SQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPV---VMHHHGRHFIHI 59
           S  ++L  KG  LI +++RGD    D++E+ +     +  +E  +   ++ H G  F+ I
Sbjct: 4   SAVYVLDLKGKVLICRNYRGDV---DMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60

Query: 60  RHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDY 119
           +H+ LYLV T+ +N     +   L ++  +  +Y   L E +I  N  ++YELLDE++D+
Sbjct: 61  KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120

Query: 120 GYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRS 179
           GY QTT +++L+ +I  E                  G + +     P +  +  V S RS
Sbjct: 121 GYPQTTDSKILQEYITQE------------------GHKLETGAPRPPATVTNAV-SWRS 161

Query: 180 D--QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVG 237
           +  + +KNEVFLDV+E +++L+++NG++L+ ++ G I+++ FL    E+R+GL ++    
Sbjct: 162 EGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFD 221

Query: 238 KSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFR 297
            +  RG    + +++V FH  V L  FE+ R +   PP GE  +M Y+L+  +    P  
Sbjct: 222 NTG-RGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVK---PLI 277

Query: 298 LFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELA 357
              SV       R++  +K +     +S A NV +H+P+P    S   + +    K    
Sbjct: 278 WIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPE 337

Query: 358 EGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCS 417
              + W +    GG +        +P        G           P S+ FE+P  T S
Sbjct: 338 NSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKP---------PISVKFEIPYFTTS 388

Query: 418 GLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
           G+QVR+L++  +    A P  WVR+++ +  Y +R
Sbjct: 389 GIQVRYLKIIEKSGYQALP--WVRYITQNGDYQLR 421


>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
           b [Homo sapiens]
          Length = 433

 Score =  183 bits (465), Expect = 2e-46
 Identities = 130/464 (28%), Positives = 225/464 (48%), Gaps = 44/464 (9%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR 60
           MI   FI + KG+ LI + +R D G   V       +       SPV  +     F H++
Sbjct: 1   MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVT-NIARTSFFHVK 59

Query: 61  HSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYG 120
            S ++L   T +NV+   + E L ++  ++  Y G + E  I  N  L+YELLDE+LD+G
Sbjct: 60  RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119

Query: 121 YVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD 180
           Y Q + T  L+ FI  + + S+               + +QS++  S    +        
Sbjct: 120 YPQNSETGALKTFITQQGIKSQ--------------TKEEQSQIT-SQVTGQIGWRREGI 164

Query: 181 QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK-- 238
           + ++NE+FLDV+E +++L++  G +L   V G + +KS+L    E + G+ ++  + K  
Sbjct: 165 KYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQG 224

Query: 239 -----SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSP 293
                   +     I +D+ +FH  V L +F+S R +   PP GE  +MRY+ + D+   
Sbjct: 225 KGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDI--I 282

Query: 294 LPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQK 353
           LPFR+ P V+ + G  +L+V + ++ +      A  + + +P P     +       + K
Sbjct: 283 LPFRVIPLVR-EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAK 341

Query: 354 AELAEGALRWDLPRVQG--GSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFEL 411
            + +E A+ W + R+ G   SQ+S   ++        P++     A P    P S++FE+
Sbjct: 342 YKASENAIVWKIKRMAGMKESQISAEIEL-------LPTNDKKKWARP----PISMNFEV 390

Query: 412 PRHTCSGLQVRFLRLAFRPCGNANPH---KWVRHLSHSDAYVIR 452
           P    SGL+VR+L++ F P  N + H   KWVR++  S  Y  R
Sbjct: 391 P-FAPSGLKVRYLKV-FEPKLNYSDHDVIKWVRYIGRSGIYETR 432


>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
           a [Homo sapiens]
          Length = 435

 Score =  183 bits (464), Expect = 3e-46
 Identities = 130/464 (28%), Positives = 225/464 (48%), Gaps = 42/464 (9%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIR 60
           MI   FI + KG+ LI + +R D G   V       +       SPV  +     F H++
Sbjct: 1   MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVT-NIARTSFFHVK 59

Query: 61  HSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYG 120
            S ++L   T +NV+   + E L ++  ++  Y G + E  I  N  L+YELLDE+LD+G
Sbjct: 60  RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG 119

Query: 121 YVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD 180
           Y Q + T  L+ FI  + + S+               + +QS++  S    +        
Sbjct: 120 YPQNSETGALKTFITQQGIKSQ------------HQTKEEQSQIT-SQVTGQIGWRREGI 166

Query: 181 QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK-- 238
           + ++NE+FLDV+E +++L++  G +L   V G + +KS+L    E + G+ ++  + K  
Sbjct: 167 KYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQG 226

Query: 239 -----SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSP 293
                   +     I +D+ +FH  V L +F+S R +   PP GE  +MRY+ + D+   
Sbjct: 227 KGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDI--I 284

Query: 294 LPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQK 353
           LPFR+ P V+ + G  +L+V + ++ +      A  + + +P P     +       + K
Sbjct: 285 LPFRVIPLVR-EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAK 343

Query: 354 AELAEGALRWDLPRVQG--GSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFEL 411
            + +E A+ W + R+ G   SQ+S   ++        P++     A P    P S++FE+
Sbjct: 344 YKASENAIVWKIKRMAGMKESQISAEIEL-------LPTNDKKKWARP----PISMNFEV 392

Query: 412 PRHTCSGLQVRFLRLAFRPCGNANPH---KWVRHLSHSDAYVIR 452
           P    SGL+VR+L++ F P  N + H   KWVR++  S  Y  R
Sbjct: 393 P-FAPSGLKVRYLKV-FEPKLNYSDHDVIKWVRYIGRSGIYETR 434


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score =  182 bits (462), Expect = 5e-46
 Identities = 131/453 (28%), Positives = 221/453 (48%), Gaps = 38/453 (8%)

Query: 3   SQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGR-HFIHIRH 61
           S  FIL  KG PLI ++++GD     + E F   L     + +   +  HG+ HF+ I+H
Sbjct: 4   SAVFILDVKGKPLISRNYKGDVAMSKI-EHFMPLLVQREEEGALAPLLSHGQVHFLWIKH 62

Query: 62  SGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGY 121
           S LYLV TTS+N +   +   L +   +  +Y   L E +I  N  +VYELLDE++D+G+
Sbjct: 63  SNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDFGF 122

Query: 122 VQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSD- 180
            QTT +++L+ +I  ++                   ET +S+V P+   +   +S RS+ 
Sbjct: 123 PQTTDSKILQEYITQQS----------------NKLETGKSRVPPTVTNA---VSWRSEG 163

Query: 181 -QSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKS 239
            + +KNEVF+DV+E +++L+ +NGS+L  ++ G I+LK FL    E+R+GL +      +
Sbjct: 164 IKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELT 223

Query: 240 ELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLF 299
             R     + +++V FH  V L  F++ R +   PP G+  +M Y+LS  +    P    
Sbjct: 224 G-RSKNKSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVK---PLIWI 279

Query: 300 PSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEG 359
            SV       R+++ +K +     +S A  V + +P+P    S   + S    K      
Sbjct: 280 ESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERN 339

Query: 360 ALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGL 419
            + W +    GG +        +P        G           P  + FE+P  T SG+
Sbjct: 340 VVIWSIKSFPGGKEYLMRAHFGLPSVEKEEVEGRP---------PIGVKFEIPYFTVSGI 390

Query: 420 QVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
           QVR++++  +    A P  WVR+++ S  Y +R
Sbjct: 391 QVRYMKIIEKSGYQALP--WVRYITQSGDYQLR 421


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score =  180 bits (457), Expect = 2e-45
 Identities = 126/467 (26%), Positives = 224/467 (47%), Gaps = 54/467 (11%)

Query: 3   SQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPV---VMHHHGRHFIHI 59
           S  ++L  KG  LI +++RGD    D++E+ +     +  +E  +   ++ H G  F+ I
Sbjct: 4   SAVYVLDLKGKVLICRNYRGDV---DMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60

Query: 60  RHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDY 119
           +H+ LYLV T+ +N     +   L ++  +  +Y   L E +I  N  ++YELLDE++D+
Sbjct: 61  KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 120

Query: 120 GYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRS 179
           GY QTT +++L+ +I  E                  G + +     P +  +  V S RS
Sbjct: 121 GYPQTTDSKILQEYITQE------------------GHKLETGAPRPPATVTNAV-SWRS 161

Query: 180 D--QSQKNEVFLDVVERLSVL------------IASNGSLLKVDVQGEIRLKSFLPSGSE 225
           +  + +KNEVFLDV+E +++L            +++NG++L+ ++ G I+++ FL    E
Sbjct: 162 EGIKYRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPE 221

Query: 226 MRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQ 285
           +R+GL ++     +  RG    + +++V FH  V L  FE+ R +   PP GE  +M Y+
Sbjct: 222 LRLGLNDKVLFDNTG-RGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYR 280

Query: 286 LSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQ 345
           L+  +    P     SV       R++  +K +     +S A NV +H+P+P    S   
Sbjct: 281 LNTHVK---PLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKF 337

Query: 346 ELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPA 405
           + +    K       + W +    GG +        +P        G           P 
Sbjct: 338 KTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKP---------PI 388

Query: 406 SLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
           S+ FE+P  T SG+QVR+L++  +    A P  WVR+++ +  Y +R
Sbjct: 389 SVKFEIPYFTTSGIQVRYLKIIEKSGYQALP--WVRYITQNGDYQLR 433


>gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score =  111 bits (277), Expect = 2e-24
 Identities = 104/460 (22%), Positives = 190/460 (41%), Gaps = 51/460 (11%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58
           MI   F+++  GD  + K ++     + V + F+         E+  PV+   H  + I 
Sbjct: 1   MIHSLFLINCSGDIFLEKHWKSVVS-QSVCDYFFEAQEKAADVENVPPVISTPH-HYLIS 58

Query: 59  IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118
           I    L+ V      V P  ++E L R+A    DY G   E  I  NV +VYELL+E+LD
Sbjct: 59  IYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLD 118

Query: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178
            G+   T + +L+  I+   ++         S V      +      P+   S       
Sbjct: 119 NGFPLATESNILKELIKPPTILR--------SVVNSITGSSNVGDTLPTGQLSNIPWRRA 170

Query: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238
             +   NE + DVVE +  +I  +GS +  ++QG I     L    ++ +          
Sbjct: 171 GVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSF-------- 222

Query: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298
                  P + +D+VSFH  +    +ES R+L   PP G   ++ Y++S      +P  +
Sbjct: 223 -----MNPRL-LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYV 276

Query: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356
             S+ +   S  GR  + +  + ++    + + V +H  +P+ V++++   +      + 
Sbjct: 277 KHSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVH--MPKVVLNMNLTPTQGSYTFDP 334

Query: 357 AEGALRWDLPRV--QGGSQLSGL--FQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELP 412
               L WD+ ++  Q    L GL   Q   P P   PS               ++ F++ 
Sbjct: 335 VTKVLTWDVGKITPQKLPSLKGLVNLQSGAPKPEENPS--------------LNIQFKIQ 380

Query: 413 RHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
           +   SGL+V  L +         P K V++++ +  + +R
Sbjct: 381 QLAISGLKVNRLDMYGE---KYKPFKGVKYVTKAGKFQVR 417


>gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score =  111 bits (277), Expect = 2e-24
 Identities = 104/460 (22%), Positives = 190/460 (41%), Gaps = 51/460 (11%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58
           MI   F+++  GD  + K ++     + V + F+         E+  PV+   H  + I 
Sbjct: 1   MIHSLFLINCSGDIFLEKHWKSVVS-QSVCDYFFEAQEKAADVENVPPVISTPH-HYLIS 58

Query: 59  IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118
           I    L+ V      V P  ++E L R+A    DY G   E  I  NV +VYELL+E+LD
Sbjct: 59  IYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLD 118

Query: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178
            G+   T + +L+  I+   ++         S V      +      P+   S       
Sbjct: 119 NGFPLATESNILKELIKPPTILR--------SVVNSITGSSNVGDTLPTGQLSNIPWRRA 170

Query: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238
             +   NE + DVVE +  +I  +GS +  ++QG I     L    ++ +          
Sbjct: 171 GVKYTNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSF-------- 222

Query: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298
                  P + +D+VSFH  +    +ES R+L   PP G   ++ Y++S      +P  +
Sbjct: 223 -----MNPRL-LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYV 276

Query: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356
             S+ +   S  GR  + +  + ++    + + V +H  +P+ V++++   +      + 
Sbjct: 277 KHSISFKENSSCGRFDITIGPKQNMGKTIEGITVTVH--MPKVVLNMNLTPTQGSYTFDP 334

Query: 357 AEGALRWDLPRV--QGGSQLSGL--FQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELP 412
               L WD+ ++  Q    L GL   Q   P P   PS               ++ F++ 
Sbjct: 335 VTKVLTWDVGKITPQKLPSLKGLVNLQSGAPKPEENPS--------------LNIQFKIQ 380

Query: 413 RHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
           +   SGL+V  L +         P K V++++ +  + +R
Sbjct: 381 QLAISGLKVNRLDMYGE---KYKPFKGVKYVTKAGKFQVR 417


>gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score =  104 bits (260), Expect = 1e-22
 Identities = 104/457 (22%), Positives = 188/457 (41%), Gaps = 45/457 (9%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58
           MI   F+++S GD  + K ++     R V + F+         E+  PV+   H      
Sbjct: 1   MIHSLFLINSSGDIFLEKHWKSVVS-RSVCDYFFEAQERATEAENVPPVIPTPHHYLLSV 59

Query: 59  IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118
            RH   ++ V  +E V P  ++E L R+     DY G   E  I  NV +VYE+L+E+LD
Sbjct: 60  YRHKIFFVAVIQTE-VPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLD 118

Query: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178
            G+   T + +L+  I+   ++         + V      T      P+   S       
Sbjct: 119 NGFPLATESNILKELIKPPTILR--------TVVNTITGSTNVGDQLPTGQLSVVPWRRT 170

Query: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238
             +   NE + DV+E +  +I  +GS +  ++QG I     L    ++ +          
Sbjct: 171 GVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSF-------- 222

Query: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298
                  P + +D+VSFH  V    +ES RIL   PP G   ++ Y +S      +P  +
Sbjct: 223 -----MNPRL-LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYV 276

Query: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356
             ++ +   S  GR ++ +  +  +    + + V     +P+GV+++S   S      + 
Sbjct: 277 KHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQ--MPKGVLNMSLTPSQGTHTFDP 334

Query: 357 AEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPA-SLSFELPRHT 415
               L WD+ ++             +P   G  S  L   AS     P  +L F++ +  
Sbjct: 335 VTKMLSWDVGKIN---------PQKLPSLKGTMS--LQAGASKPDENPTINLQFKIQQLA 383

Query: 416 CSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
            SGL+V  L +         P K +++++ +  + +R
Sbjct: 384 ISGLKVNRLDMYGE---KYKPFKGIKYMTKAGKFQVR 417


>gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score =  104 bits (260), Expect = 1e-22
 Identities = 104/457 (22%), Positives = 188/457 (41%), Gaps = 45/457 (9%)

Query: 1   MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDES--PVVMHHHGRHFIH 58
           MI   F+++S GD  + K ++     R V + F+         E+  PV+   H      
Sbjct: 1   MIHSLFLINSSGDIFLEKHWKSVVS-RSVCDYFFEAQERATEAENVPPVIPTPHHYLLSV 59

Query: 59  IRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLD 118
            RH   ++ V  +E V P  ++E L R+     DY G   E  I  NV +VYE+L+E+LD
Sbjct: 60  YRHKIFFVAVIQTE-VPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLD 118

Query: 119 YGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSR 178
            G+   T + +L+  I+   ++         + V      T      P+   S       
Sbjct: 119 NGFPLATESNILKELIKPPTILR--------TVVNTITGSTNVGDQLPTGQLSVVPWRRT 170

Query: 179 SDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGK 238
             +   NE + DV+E +  +I  +GS +  ++QG I     L    ++ +          
Sbjct: 171 GVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSF-------- 222

Query: 239 SELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRL 298
                  P + +D+VSFH  V    +ES RIL   PP G   ++ Y +S      +P  +
Sbjct: 223 -----MNPRL-LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYV 276

Query: 299 FPSVQWDRGS--GRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAEL 356
             ++ +   S  GR ++ +  +  +    + + V     +P+GV+++S   S      + 
Sbjct: 277 KHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQ--MPKGVLNMSLTPSQGTHTFDP 334

Query: 357 AEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPA-SLSFELPRHT 415
               L WD+ ++             +P   G  S  L   AS     P  +L F++ +  
Sbjct: 335 VTKMLSWDVGKIN---------PQKLPSLKGTMS--LQAGASKPDENPTINLQFKIQQLA 383

Query: 416 CSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIR 452
            SGL+V  L +         P K +++++ +  + +R
Sbjct: 384 ISGLKVNRLDMYGE---KYKPFKGIKYMTKAGKFQVR 417


>gi|11863154 archain isoform 1 [Homo sapiens]
          Length = 511

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/81 (27%), Positives = 42/81 (51%)

Query: 64  LYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGYVQ 123
           LY+V+ T++N +    LE L   + ++ +YC +L E  IS +   +    DE++  GY +
Sbjct: 64  LYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRE 123

Query: 124 TTSTEMLRNFIQTEAVVSKPF 144
             +   +R F + ++   K F
Sbjct: 124 NVNLAQIRTFTEMDSHEEKVF 144


>gi|26787993 stonin 1 [Homo sapiens]
          Length = 735

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 20/197 (10%)

Query: 173 PVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLT- 231
           P +S      ++ E+ L++V+     +   G  ++  V  +I    F+    E  + L  
Sbjct: 401 PAVSKPKKNYEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND 460

Query: 232 -------EEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQG-ELTVMR 283
                  E +    SE +G    I + +  FH  VN+ EFE  RI++  P       +MR
Sbjct: 461 LELPKRDESYYEKDSEKKG----IDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMR 516

Query: 284 YQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQA------LNVRLHLPLP 337
           ++   +    LPF L   V        LQ ++ +       S A       N+R+H P+P
Sbjct: 517 FKTLYN-GDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVP 575

Query: 338 RGVVSLSQELSSPEQKA 354
              +     ++   QK+
Sbjct: 576 SQWIKALWTMNLQRQKS 592


>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
          Length = 1182

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 20/197 (10%)

Query: 173 PVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLT- 231
           P +S      ++ E+ L++V+     +   G  ++  V  +I    F+    E  + L  
Sbjct: 401 PAVSKPKKNYEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND 460

Query: 232 -------EEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQG-ELTVMR 283
                  E +    SE +G    I + +  FH  VN+ EFE  RI++  P       +MR
Sbjct: 461 LELPKRDESYYEKDSEKKG----IDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMR 516

Query: 284 YQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQA------LNVRLHLPLP 337
           ++   +    LPF L   V        LQ ++ +       S A       N+R+H P+P
Sbjct: 517 FKTLYN-GDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVP 575

Query: 338 RGVVSLSQELSSPEQKA 354
              +     ++   QK+
Sbjct: 576 SQWIKALWTMNLQRQKS 592


>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
           sapiens]
          Length = 157

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 25/79 (31%), Positives = 38/79 (48%)

Query: 57  IHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEV 116
           ++ R++ LY      +  +    LE++ R   LL  Y GS+ E  I  N    Y +LDE 
Sbjct: 57  VYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEF 116

Query: 117 LDYGYVQTTSTEMLRNFIQ 135
           L  G VQ TS + +   I+
Sbjct: 117 LLGGEVQETSKKNVLKAIE 135


>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
           sapiens]
          Length = 158

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 26/79 (32%), Positives = 37/79 (46%)

Query: 57  IHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEV 116
           ++ R++ LY         +    LEL+ R   LL  Y GS+ E  I  N    Y +LDE 
Sbjct: 58  VYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEF 117

Query: 117 LDYGYVQTTSTEMLRNFIQ 135
           L  G VQ TS + +   I+
Sbjct: 118 LMGGDVQDTSKKSVLKAIE 136


>gi|21361863 stonin 2 [Homo sapiens]
          Length = 905

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 45/195 (23%), Positives = 84/195 (43%), Gaps = 19/195 (9%)

Query: 184 KNEVFLDVVERLSVLIAS-NGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSELR 242
           + E+ +DV +  S +++  +  +L+  V   I + SFL   +E R+GL +    G   + 
Sbjct: 568 EEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILVKGNEIVL 627

Query: 243 GYG-------PGIRVDEVSFHSSVNLDEFESHRILRLQPPQG-ELTVMRYQLSDDLPSPL 294
                       I++ E  FH  V+ D F + R++   P       +MR++ +      L
Sbjct: 628 RQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACRFELMRFR-TVFAEKTL 686

Query: 295 PFRLFPSVQWDRGSGRLQVYLKLRC------DLLSKSQALNVRLHLPLP-RGVVSLSQE- 346
           PF L  +   +     +Q +L++        D L++    NV +  P+P   V +  +E 
Sbjct: 687 PFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIRYPVPSEWVKNFRRES 746

Query: 347 -LSSPEQKAELAEGA 360
            L     KA++  GA
Sbjct: 747 VLGEKSLKAKVNRGA 761


>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
           [Homo sapiens]
          Length = 154

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/73 (28%), Positives = 35/73 (47%)

Query: 57  IHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEV 116
           ++ R++ LY         +    LE++ R   LL  Y G++ E  I  N    Y +LDE 
Sbjct: 58  VYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEF 117

Query: 117 LDYGYVQTTSTEM 129
           +  G +Q TS ++
Sbjct: 118 IIGGEIQETSKKI 130


>gi|13994335 Mix-like homeobox protein 1 [Homo sapiens]
          Length = 232

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 1/64 (1%)

Query: 366 PRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLR 425
           P   G +  +G    D PGP  PP   L + A P G    S S    R + S  Q++ L 
Sbjct: 44  PAGPGPATFAGFLGRD-PGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLE 102

Query: 426 LAFR 429
           L FR
Sbjct: 103 LVFR 106


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 25/131 (19%)

Query: 283 RYQLSD---DLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRG 339
           R+ ++D   +L + +P    P ++W++G+      LK   D + K Q    R        
Sbjct: 359 RFNINDRIKELGTLIPKSSDPEMRWNKGT-----ILKASVDYIRKLQKEQQR-------- 405

Query: 340 VVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASP 399
               S++L S ++  E A  +L+  +  ++  +Q+ GL     P PP P    L+T+++ 
Sbjct: 406 ----SKDLESRQRSLEQANRSLQLRIQELELQAQIHGL-----PVPPTPGLLSLATTSAS 456

Query: 400 LGLGPASLSFE 410
             L P  L  E
Sbjct: 457 DSLKPEQLDIE 467


>gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens]
          Length = 510

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 3/26 (11%)

Query: 377 LFQMDVPGPPGPPSHGLSTSASPLGL 402
           L++  VPG PGPP+HG     SP+G+
Sbjct: 270 LYEHGVPGMPGPPAHGFQ---SPMGI 292


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/22 (63%), Positives = 15/22 (68%), Gaps = 1/22 (4%)

Query: 383  PGPPGPPSHGLSTSASPLGLGP 404
            PGPPGPP  G+  SA   GLGP
Sbjct: 1208 PGPPGPPGPGIDMSAF-AGLGP 1228


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/22 (63%), Positives = 15/22 (68%), Gaps = 1/22 (4%)

Query: 383  PGPPGPPSHGLSTSASPLGLGP 404
            PGPPGPP  G+  SA   GLGP
Sbjct: 1139 PGPPGPPGPGIDMSAF-AGLGP 1159


>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
           sapiens]
          Length = 896

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 7/101 (6%)

Query: 335 PLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLS 394
           P    + SLSQ L   EQ+ EL + AL   L  ++     S L     P PPG       
Sbjct: 11  PAREALQSLSQRLRVQEQEMELVKAALAEALRLLRLQVPPSSLQGSGTPAPPG------D 64

Query: 395 TSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGNAN 435
           + A+P GL P      + R T +  +V  L+ +  P G +N
Sbjct: 65  SLAAPPGLPPTCTPSLVSRGTQTETEVE-LKSSPGPPGLSN 104


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 335 PLPRGVVSLSQELSSPEQKAELAEGALRWDLPR--VQGGSQLSGLFQMDVPGPPGP 388
           P P+ +   +Q L   +Q   LA GA++   P   VQ GSQL G  +   P PP P
Sbjct: 724 PQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779


>gi|114431236 zinc finger protein 462 [Homo sapiens]
          Length = 2506

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 6/98 (6%)

Query: 308 SGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQK--AELAEGALRWDL 365
           SG+  VY    C    KS +L +  H     G  S    ++S  +   + L EG + ++ 
Sbjct: 464 SGKTAVYKCDECPFTCKS-SLKLGAHKQCHTGTTSDWDAVNSQSESISSSLNEGVVSYES 522

Query: 366 PRVQG---GSQLSGLFQMDVPGPPGPPSHGLSTSASPL 400
             + G   G  L  L Q   P PP PP     +   PL
Sbjct: 523 SSINGRKSGVMLDPLQQQQPPQPPPPPPPPPPSQPQPL 560


>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 335 PLPRGVVSLSQELSSPEQKAELAEGALRWDLPR--VQGGSQLSGLFQMDVPGPPGP 388
           P P+ +   +Q L   +Q   LA GA++   P   VQ GSQL G  +   P PP P
Sbjct: 762 PQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817


>gi|190014615 hypothetical protein LOC157983 [Homo sapiens]
          Length = 295

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 20/45 (44%), Positives = 21/45 (46%), Gaps = 3/45 (6%)

Query: 383 PGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLA 427
           PG PG       T     GLGP S   E P HT +GL  R LR A
Sbjct: 77  PGAPGLRRAPPRTRMDSSGLGPCS---EAPLHTSAGLSGRNLRAA 118


>gi|214010212 archain isoform 2 [Homo sapiens]
          Length = 423

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 14/56 (25%), Positives = 28/56 (50%)

Query: 89  LLGDYCGSLGEGTISRNVALVYELLDEVLDYGYVQTTSTEMLRNFIQTEAVVSKPF 144
           ++ +YC +L E  IS +   +    DE++  GY +  +   +R F + ++   K F
Sbjct: 1   MIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEKVF 56


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%)

Query: 66   LVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGY-VQT 124
            L  ++SEN  P  L ELL  L   L  +C        S +VAL+++ L  +L +   + +
Sbjct: 972  LGTSSSENSQPAHLHELLCSLQKQLLAFCHINNISENSSSVALLHKHLQLLLPHATDIYS 1031

Query: 125  TSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLS 176
             S  +L+      +V  K   +  +S+ G    +   S +    + +RP+LS
Sbjct: 1032 RSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLS 1083


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 366  PRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELP 412
            P + G  QLS       P PP P    L  ++SP+G G AS    LP
Sbjct: 1862 PGLMGTEQLSTELDSKTPTPPAPTL--LKMTSSPVGPGTASAGPSLP 1906


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,259,733
Number of Sequences: 37866
Number of extensions: 903369
Number of successful extensions: 3747
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3671
Number of HSP's gapped (non-prelim): 63
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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