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Search of human proteins with 148763347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo
sapiens]
(780 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 1567 0.0
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1540 0.0
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 1532 0.0
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1518 0.0
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1510 0.0
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1468 0.0
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1441 0.0
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1042 0.0
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 361 2e-99
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 302 7e-82
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 299 8e-81
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 291 2e-78
gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens] 290 5e-78
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 288 2e-77
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 270 4e-72
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 268 1e-71
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 253 5e-67
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 253 5e-67
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 253 6e-67
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 251 2e-66
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 246 8e-65
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 246 8e-65
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 242 8e-64
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 240 4e-63
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 239 9e-63
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 237 4e-62
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 237 4e-62
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 233 4e-61
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 229 1e-59
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 228 2e-59
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 1567 bits (4057), Expect = 0.0
Identities = 780/780 (100%), Positives = 780/780 (100%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180
HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR
Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
Query: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 420
RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV
Sbjct: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 420
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
Sbjct: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY
Sbjct: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 660
STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT
Sbjct: 601 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 660
Query: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
Sbjct: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
Query: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 1540 bits (3986), Expect = 0.0
Identities = 772/782 (98%), Positives = 773/782 (98%), Gaps = 2/782 (0%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK RH SHSAEGGK
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGK 120
Query: 121 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 178
HARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
Sbjct: 121 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 180
Query: 179 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 238
MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
Sbjct: 181 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 240
Query: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298
ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
Sbjct: 241 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 300
Query: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 358
EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP
Sbjct: 301 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 360
Query: 359 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR 418
ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCR
Sbjct: 361 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCR 420
Query: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ
Sbjct: 421 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 480
Query: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL
Sbjct: 481 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 540
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAK
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
EYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKK
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718
MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 720
Query: 719 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 778
MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL
Sbjct: 721 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 780
Query: 779 KF 780
KF
Sbjct: 781 KF 782
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 1532 bits (3967), Expect = 0.0
Identities = 769/780 (98%), Positives = 769/780 (98%), Gaps = 10/780 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------K 110
Query: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180
HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR
Sbjct: 111 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 170
Query: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
Sbjct: 171 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 230
Query: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
Query: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 350
Query: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 420
RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV
Sbjct: 351 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 410
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
Sbjct: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 470
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
Sbjct: 471 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 530
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY
Sbjct: 531 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 590
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 660
STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT
Sbjct: 591 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 650
Query: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
Sbjct: 651 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 710
Query: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 711 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 1518 bits (3929), Expect = 0.0
Identities = 764/782 (97%), Positives = 765/782 (97%), Gaps = 13/782 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-----------K 109
Query: 121 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 178
HARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
Sbjct: 110 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 169
Query: 179 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 238
MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
Sbjct: 170 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 229
Query: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298
ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
Sbjct: 230 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289
Query: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 358
EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP
Sbjct: 290 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 349
Query: 359 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR 418
ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCR
Sbjct: 350 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCR 409
Query: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ
Sbjct: 410 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 469
Query: 479 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL
Sbjct: 470 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 529
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAK
Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 589
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
EYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKK
Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718
MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS
Sbjct: 650 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 709
Query: 719 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 778
MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL
Sbjct: 710 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 769
Query: 779 KF 780
KF
Sbjct: 770 KF 771
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 1510 bits (3909), Expect = 0.0
Identities = 764/791 (96%), Positives = 765/791 (96%), Gaps = 22/791 (2%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-----------K 109
Query: 121 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQL 169
HARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQL
Sbjct: 110 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQL 169
Query: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
Query: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK 409
NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPK
Sbjct: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK 409
Query: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
Sbjct: 410 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR 469
Query: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 529
EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI
Sbjct: 470 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI 529
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 589
QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYR
Sbjct: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR 589
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 649
APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPG
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 649
Query: 650 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
YSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR
Sbjct: 650 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
Query: 710 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 769
ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
Sbjct: 710 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA 769
Query: 770 SAAGPGFSLKF 780
SAAGPGFSLKF
Sbjct: 770 SAAGPGFSLKF 780
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 1468 bits (3800), Expect = 0.0
Identities = 735/748 (98%), Positives = 737/748 (98%), Gaps = 2/748 (0%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEKCRHHSHSAEGGKHARVKE--REHERRKRHREEQDKARREWERQKRR 152
EKVHHRKDEKRKEK RH SHSAEGGKHARVKE REHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRR 120
Query: 153 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 212
EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH
Sbjct: 121 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 180
Query: 213 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 272
HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER
Sbjct: 181 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 240
Query: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332
KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ
Sbjct: 241 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 300
Query: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 392
SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV
Sbjct: 301 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 360
Query: 393 PDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 452
PDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK
Sbjct: 361 PDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 420
Query: 453 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 512
RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM
Sbjct: 421 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 480
Query: 513 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 572
ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY
Sbjct: 481 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 540
Query: 573 GSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQI 632
GSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQI
Sbjct: 541 GSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQI 600
Query: 633 NKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 692
NKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF
Sbjct: 601 NKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 660
Query: 693 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 752
PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD
Sbjct: 661 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 720
Query: 753 DDLKETGFHLTTTNQGASAAGPGFSLKF 780
DDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 DDLKETGFHLTTTNQGASAAGPGFSLKF 748
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 1441 bits (3731), Expect = 0.0
Identities = 726/748 (97%), Positives = 728/748 (97%), Gaps = 13/748 (1%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEKCRHHSHSAEGGKHARVKE--REHERRKRHREEQDKARREWERQKRR 152
EKVHHRKDEKRKEK KHARVKE REHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEK-----------KHARVKEKEREHERRKRHREEQDKARREWERQKRR 109
Query: 153 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 212
EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH
Sbjct: 110 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 169
Query: 213 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 272
HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER
Sbjct: 170 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 229
Query: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332
KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ
Sbjct: 230 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 289
Query: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 392
SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV
Sbjct: 290 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 349
Query: 393 PDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 452
PDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK
Sbjct: 350 PDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 409
Query: 453 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 512
RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM
Sbjct: 410 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 469
Query: 513 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 572
ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY
Sbjct: 470 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 529
Query: 573 GSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQI 632
GSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQI
Sbjct: 530 GSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQI 589
Query: 633 NKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 692
NKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF
Sbjct: 590 NKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 649
Query: 693 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 752
PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD
Sbjct: 650 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 709
Query: 753 DDLKETGFHLTTTNQGASAAGPGFSLKF 780
DDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 710 DDLKETGFHLTTTNQGASAAGPGFSLKF 737
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 1042 bits (2694), Expect = 0.0
Identities = 521/526 (99%), Positives = 522/526 (99%)
Query: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314
MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374
EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE
Sbjct: 61 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 120
Query: 375 EVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 434
EVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY
Sbjct: 121 EVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 180
Query: 435 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 494
GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM
Sbjct: 181 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 240
Query: 495 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 554
DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL
Sbjct: 241 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 300
Query: 555 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 614
LSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWSVGCIFG
Sbjct: 301 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG 360
Query: 615 ELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFG 674
ELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNNLRKRFG
Sbjct: 361 ELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFG 420
Query: 675 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 734
ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR
Sbjct: 421 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 480
Query: 735 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 481 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 526
Score = 33.9 bits (76), Expect = 0.60
Identities = 41/190 (21%), Positives = 65/190 (34%), Gaps = 36/190 (18%)
Query: 102 DEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 161
D +RK S SAE G + E E + EE++ + E
Sbjct: 15 DSERKTSSAESS-SAESGSGS-----EEEEEEEEEEEEEGSTSE---------------- 52
Query: 162 ERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS 221
E E + E+++E+ E A E+ E + E+S E++
Sbjct: 53 ------------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 100
Query: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 281
V S + R E+G+G + + E D + D +S E K +
Sbjct: 101 LVVPESRFDRDSGESEEAEEEVGEGTP--QSSALTEGDYVPDSPALSPIELKQELPKYLP 158
Query: 282 AESGSGSEEE 291
A G S EE
Sbjct: 159 ALQGCRSVEE 168
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 361 bits (926), Expect = 2e-99
Identities = 175/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
Query: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVT WYRAPELLLG
Sbjct: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVV 656
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP+V
Sbjct: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
Query: 657 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 716
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
Query: 717 PSMFPTWPAKSEQQRVKRGTSPRPPEG 743
P + PT+P R KR +P EG
Sbjct: 332 PELMPTFP----HHRNKR-AAPATSEG 353
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 302 bits (774), Expect = 7e-82
Identities = 147/288 (51%), Positives = 204/288 (70%), Gaps = 6/288 (2%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 743
R +A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 240 RATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 282
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 299 bits (765), Expect = 8e-81
Identities = 151/163 (92%), Positives = 151/163 (92%), Gaps = 10/163 (6%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK----------WK 110
Query: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 163
HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 111 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
Score = 36.2 bits (82), Expect = 0.12
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 6/140 (4%)
Query: 102 DEKRKEKCRHHSHSAEGGKHARVKEREHE-RRKRHREEQDKARREWERQKRREMAREHSR 160
DEK K + + K + +E + E +R ++ +++D R E + R+ E +
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
Query: 161 RERD--RLEQLERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRT 215
R R + +E + E + + + +Q KE+ R +E+RKE+ AR + H R
Sbjct: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
Query: 216 MREDYSDKVKASHWSRSPPR 235
R W R R
Sbjct: 123 KRHREEQDKARREWERQKRR 142
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 291 bits (744), Expect = 2e-78
Identities = 150/165 (90%), Positives = 150/165 (90%), Gaps = 12/165 (7%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEK----------RK 110
Query: 121 HARV--KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 163
HARV KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 111 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
Score = 35.4 bits (80), Expect = 0.20
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
Query: 230 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
Query: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
Score = 35.0 bits (79), Expect = 0.27
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 225
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
Query: 226 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 285
+PP++ ++EK R D +RK + E
Sbjct: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
Query: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
E + EE+++ E + E E E
Sbjct: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
>gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens]
Length = 283
Score = 290 bits (741), Expect = 5e-78
Identities = 144/288 (50%), Positives = 200/288 (69%), Gaps = 12/288 (4%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLF------ 233
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 743
+A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 234 MATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 276
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 288 bits (736), Expect = 2e-77
Identities = 136/258 (52%), Positives = 189/258 (73%), Gaps = 1/258 (0%)
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 515
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 516 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 576 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 696 RISAEDGLKHEYFRETPL 713
R +A D L+ YF+E PL
Sbjct: 240 RATAGDCLESSYFKEKPL 257
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 270 bits (690), Expect = 4e-72
Identities = 135/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVT WYRAPE+LLG+K
Sbjct: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
Y+TAVD+WS+GCIF E++T+K LFPG+SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 268 bits (686), Expect = 1e-71
Identities = 132/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVT WYRAPE+LLG K
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
YSTAVD+WS+GCIF E++T++ LFPG+SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 253 bits (646), Expect = 5e-67
Identities = 211/769 (27%), Positives = 332/769 (43%), Gaps = 71/769 (9%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRK--------DEKRKEKCRHHSHSAEGGKHARV 124
Q R K + R+ +R HS GG +
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 125 KEREHERRKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQ 183
R+ RR + + R + HSR R R RL R R R +
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLS---RSRSRHSSISPST 442
Query: 184 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFEL 243
+ E ++ + EA R A ++ + + + P + E
Sbjct: 443 LTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTET 502
Query: 244 GDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGSEEEEEEEE 296
K VK+ K+E S + + + KT + + E+ ++ ++
Sbjct: 503 SASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAV 562
Query: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE--------EMSEDEER 348
+E ++ EE +E+ + T S + EQ V+ + ED+E
Sbjct: 563 IVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEA 622
Query: 349 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP------ALLPIE 402
++ + V + E E+ + P L GD + SP L +
Sbjct: 623 DSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSK 677
Query: 403 LKQEL--PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK 455
+ ++ P+Y + G R V++F + I EGTYG VY+A+DK T E+VALK+++
Sbjct: 678 RRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHD 507
++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+V Y++HD
Sbjct: 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHD 797
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
L L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G +K+ DFG
Sbjct: 798 LMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFG 857
Query: 568 LAREYGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 626
LAR Y S + YT V+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N
Sbjct: 858 LARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 917
Query: 627 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 686
E+ Q+ + + G+P +WP +LP M + LR+ F + DL +
Sbjct: 918 QELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFD 976
Query: 687 KFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 734
L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 977 YMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 33.5 bits (75), Expect = 0.78
Identities = 52/242 (21%), Positives = 82/242 (33%), Gaps = 41/242 (16%)
Query: 149 QKRREMAREHSRRERDRLEQLERKRERERKMREQQK---EQREQKERERRAEERRKE--- 202
Q+R E + RR+R ++R RE + R+ Q+ E + + R + E R E
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 203 ---------REARREVSAHHRTMREDYSDKVKASHW--SRSPP----RPPRERFELGDGR 247
R ++ + R+D K S S+ PP PP+ E D
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYRE--DKT 305
Query: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
+P + L D S R + S S + S +G GS+
Sbjct: 306 EPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG-------------GSSPYS 352
Query: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 367
+ S S +S + +VS S R + + P S R SG
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYSPVLRRSG 407
Query: 368 ES 369
+S
Sbjct: 408 KS 409
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/166 (22%), Positives = 55/166 (33%), Gaps = 17/166 (10%)
Query: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRH 135
RGE + + + S + K HR+ +R GG A H
Sbjct: 190 RGEGSERRPRRDRRSSSGRSKERHREHRRR--------DGQRGGSEASKSRSRHSHSGEE 241
Query: 136 REEQDKARREWERQKRREMA-----REHSRRERDRLEQLERKRERERKMREQQKEQREQK 190
R E K+ RR+ A SR++RD + R R + +E +E
Sbjct: 242 RAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDS----KAHRSRTKSSKEPPSAYKEPP 297
Query: 191 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
+ R + K RR +S S + S SR P P
Sbjct: 298 KAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSP 343
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 253 bits (646), Expect = 5e-67
Identities = 211/769 (27%), Positives = 332/769 (43%), Gaps = 71/769 (9%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRK--------DEKRKEKCRHHSHSAEGGKHARV 124
Q R K + R+ +R HS GG +
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 125 KEREHERRKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQ 183
R+ RR + + R + HSR R R RL R R R +
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLS---RSRSRHSSISPST 442
Query: 184 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFEL 243
+ E ++ + EA R A ++ + + + P + E
Sbjct: 443 LTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTET 502
Query: 244 GDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGSEEEEEEEE 296
K VK+ K+E S + + + KT + + E+ ++ ++
Sbjct: 503 SASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAV 562
Query: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE--------EMSEDEER 348
+E ++ EE +E+ + T S + EQ V+ + ED+E
Sbjct: 563 IVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEA 622
Query: 349 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP------ALLPIE 402
++ + V + E E+ + P L GD + SP L +
Sbjct: 623 DSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSK 677
Query: 403 LKQEL--PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK 455
+ ++ P+Y + G R V++F + I EGTYG VY+A+DK T E+VALK+++
Sbjct: 678 RRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737
Query: 456 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHD 507
++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+V Y++HD
Sbjct: 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHD 797
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
L L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G +K+ DFG
Sbjct: 798 LMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFG 857
Query: 568 LAREYGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 626
LAR Y S + YT V+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N
Sbjct: 858 LARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 917
Query: 627 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 686
E+ Q+ + + G+P +WP +LP M + LR+ F + DL +
Sbjct: 918 QELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFD 976
Query: 687 KFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 734
L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 977 YMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 33.5 bits (75), Expect = 0.78
Identities = 52/242 (21%), Positives = 82/242 (33%), Gaps = 41/242 (16%)
Query: 149 QKRREMAREHSRRERDRLEQLERKRERERKMREQQK---EQREQKERERRAEERRKE--- 202
Q+R E + RR+R ++R RE + R+ Q+ E + + R + E R E
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 203 ---------REARREVSAHHRTMREDYSDKVKASHW--SRSPP----RPPRERFELGDGR 247
R ++ + R+D K S S+ PP PP+ E D
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYRE--DKT 305
Query: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
+P + L D S R + S S + S +G GS+
Sbjct: 306 EPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG-------------GSSPYS 352
Query: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 367
+ S S +S + +VS S R + + P S R SG
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYSPVLRRSG 407
Query: 368 ES 369
+S
Sbjct: 408 KS 409
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/166 (22%), Positives = 55/166 (33%), Gaps = 17/166 (10%)
Query: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRH 135
RGE + + + S + K HR+ +R GG A H
Sbjct: 190 RGEGSERRPRRDRRSSSGRSKERHREHRRR--------DGQRGGSEASKSRSRHSHSGEE 241
Query: 136 REEQDKARREWERQKRREMA-----REHSRRERDRLEQLERKRERERKMREQQKEQREQK 190
R E K+ RR+ A SR++RD + R R + +E +E
Sbjct: 242 RAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDS----KAHRSRTKSSKEPPSAYKEPP 297
Query: 191 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
+ R + K RR +S S + S SR P P
Sbjct: 298 KAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSP 343
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 253 bits (645), Expect = 6e-67
Identities = 123/297 (41%), Positives = 197/297 (66%), Gaps = 14/297 (4%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 593
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT VVT WYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEV 174
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
LLG+ YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 654 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 251 bits (640), Expect = 2e-66
Identities = 121/297 (40%), Positives = 196/297 (65%), Gaps = 14/297 (4%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 593
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT +T WYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
LLG+ YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 654 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 414
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 643
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 644 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 737 -------SPRPPEGGLGYSQLGDDD 754
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 39.7 bits (91), Expect = 0.011
Identities = 58/290 (20%), Positives = 106/290 (36%), Gaps = 37/290 (12%)
Query: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
E RL + R + S + G + + T+ +D D D +A K +
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
Query: 90 QMSRKEKVHHRKDEKRKEKCRHHSH----------SAEGGKHARVKEREHERRKRHREEQ 139
+ + + + R D R K RHH H E K V + + R
Sbjct: 94 RENDERRGSDRSD--RLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 140 DKARREWERQKRREMAREHSRRER-DRLEQLERKRERERKMREQQKEQREQK-------- 190
++ E + + ++A+ S+ R +L + + ++ERE K + + + +K
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYK 211
Query: 191 -----ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERFE 242
+R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
Query: 243 LGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 285
P KE + S + +S S R++SS E S + SG
Sbjct: 272 RQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
Score = 33.5 bits (75), Expect = 0.78
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 317
RDLL Q + ++ SS S + SGS + EE ++ + ++ S +E +
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
Query: 318 EEEETGSNSE 327
+E+T E
Sbjct: 180 HKEKTRKERE 189
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 368 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 414
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 415 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 473 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 524
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 525 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 583
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 643
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 644 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 703
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 704 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 736
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 737 -------SPRPPEGGLGYSQLGDDD 754
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 39.7 bits (91), Expect = 0.011
Identities = 58/290 (20%), Positives = 106/290 (36%), Gaps = 37/290 (12%)
Query: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
E RL + R + S + G + + T+ +D D D +A K +
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR 93
Query: 90 QMSRKEKVHHRKDEKRKEKCRHHSH----------SAEGGKHARVKEREHERRKRHREEQ 139
+ + + + R D R K RHH H E K V + + R
Sbjct: 94 RENDERRGSDRSD--RLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 140 DKARREWERQKRREMAREHSRRER-DRLEQLERKRERERKMREQQKEQREQK-------- 190
++ E + + ++A+ S+ R +L + + ++ERE K + + + +K
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYK 211
Query: 191 -----ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERFE 242
+R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 212 TVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSR 271
Query: 243 LGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 285
P KE + S + +S S R++SS E S + SG
Sbjct: 272 RQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
Score = 33.5 bits (75), Expect = 0.78
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 317
RDLL Q + ++ SS S + SGS + EE ++ + ++ S +E +
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179
Query: 318 EEEETGSNSE 327
+E+T E
Sbjct: 180 HKEKTRKERE 189
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 242 bits (618), Expect = 8e-64
Identities = 130/336 (38%), Positives = 200/336 (59%), Gaps = 16/336 (4%)
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 477
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 537
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
Query: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 597
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT+WYRAPELL GA
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
Query: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 657
+ Y VDMW+VGCI ELL + P PG+S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
Query: 658 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
Query: 718 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 745
P P ++ +++ +KR + +GGL
Sbjct: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 240 bits (612), Expect = 4e-63
Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI + + +H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
NIV + +++ K+ +V + + DLK ++ P VK+ + QLL+G+ H
Sbjct: 61 KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
+LHRDLK NLL++ G LK+ DFGLAR +G P++ Y+ VVT WYR P++L GAK
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 600 YSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
YST++DMWS GCIF EL +PLFPGN DQ+ ++F+ LGTP+E+ WP ++LP K
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
+ +P L+ G DL+ L P +RISAE+ L+H YF +
Sbjct: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 239 bits (609), Expect = 9e-63
Identities = 124/295 (42%), Positives = 183/295 (62%), Gaps = 6/295 (2%)
Query: 416 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTIL 475
G +E + L ++ EGTY VY+ + K T+ +VALK +++E E EG P T++RE++ +
Sbjct: 185 GFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLK 243
Query: 476 KAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRG 534
+H NIVT+ +IV + DK + +V Y++ DLK M+ VK + Q+LRG
Sbjct: 244 DLKHANIVTLHDIV---HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG 300
Query: 535 VKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 594
+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+ VVT WYR P++L
Sbjct: 301 LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL 360
Query: 595 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELP 654
LG+ EYST +DMW VGCIF E+ + +PLFPG++ D+++ +F+ LGTPS++ WPG S
Sbjct: 361 LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE 420
Query: 655 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
K F ++ L L +G +L+ KFL Y +R+SAE+ +KH YFR
Sbjct: 421 EFKNYNFPKYKPQPLINH-APRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFR 474
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 237 bits (604), Expect = 4e-62
Identities = 156/460 (33%), Positives = 235/460 (51%), Gaps = 19/460 (4%)
Query: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 41 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 100
Query: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE 402
S R + + S D + S A+ + EG + LT + D P
Sbjct: 101 SPVRVRMRNHPPRKI--STEDINKRLSLPADIRLPEGYLEK--LTLNSPIFDKP------ 150
Query: 403 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 462
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E EG
Sbjct: 151 LSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EG 209
Query: 463 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 522
P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 210 APCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMH 267
Query: 523 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 582
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+
Sbjct: 268 NVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNE 327
Query: 583 VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 642
VVT WYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG++ +Q++ +F+ LGTP
Sbjct: 328 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 387
Query: 643 SEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 702
+E+ WPG K + ++ L L SD G DL+ K L + RISAED
Sbjct: 388 TEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISAEDA 446
Query: 703 LKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 737
+KH +F R LP S+F + +++ R +S
Sbjct: 447 MKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 486
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 237 bits (604), Expect = 4e-62
Identities = 156/460 (33%), Positives = 235/460 (51%), Gaps = 19/460 (4%)
Query: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 35 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 94
Query: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE 402
S R + + S D + S A+ + EG + LT + D P
Sbjct: 95 SPVRVRMRNHPPRKI--STEDINKRLSLPADIRLPEGYLEK--LTLNSPIFDKP------ 144
Query: 403 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 462
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E EG
Sbjct: 145 LSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EG 203
Query: 463 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 522
P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 204 APCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMH 261
Query: 523 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 582
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+
Sbjct: 262 NVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNE 321
Query: 583 VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 642
VVT WYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG++ +Q++ +F+ LGTP
Sbjct: 322 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 381
Query: 643 SEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 702
+E+ WPG K + ++ L L SD G DL+ K L + RISAED
Sbjct: 382 TEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISAEDA 440
Query: 703 LKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 737
+KH +F R LP S+F + +++ R +S
Sbjct: 441 MKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 480
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 233 bits (595), Expect = 4e-61
Identities = 126/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
++++ L RI EG +G+V++AK +T EIVALK++ + + ++GFP +LREI L+
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
N V+ V + + ++ DL ++ ++P +VK+ + LL+GV H
Sbjct: 60 DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTQWYRAPELLLGAK 598
N I+HRDLK +NLL+S +G LK+ DFGLAR + + YT V T+WYRAPELL GA+
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
+Y VD+WSVGCI GELL PLFPG ++I+Q+ V + LGTP+ ++WP +ELP K
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 718
++F E L + +S Q DL+ +FL Y P +RI+A L H+YF PLP PS
Sbjct: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
Query: 719 MFP 721
P
Sbjct: 299 ELP 301
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 229 bits (583), Expect = 1e-59
Identities = 117/311 (37%), Positives = 183/311 (58%), Gaps = 11/311 (3%)
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
C V +++ L +I +GT+G V++A+ +KT + VALK++ ME EKEGFPIT+LREI +
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 477 AQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 530
+H N+V + EI IY+V ++ EHDL L+ + F E+K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 531 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG----SPLKAYTPVVVTQ 586
LL G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + S YT VVT
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTL 192
Query: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 646
WYR PELLLG ++Y +D+W GCI E+ T+ P+ GN+E Q+ + + G+ + ++
Sbjct: 193 WYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEV 252
Query: 647 WPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKH 705
WP + +K+ + ++ R A + D DL++K L P +RI ++D L H
Sbjct: 253 WPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNH 312
Query: 706 EYFRETPLPID 716
++F P+P D
Sbjct: 313 DFFWSDPMPSD 323
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 228 bits (580), Expect = 2e-59
Identities = 121/294 (41%), Positives = 175/294 (59%), Gaps = 5/294 (1%)
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
+ ++ L ++ EG+Y VY+ K K ++VALK +++++E EG P T++RE + + +H
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHA 173
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
NIV + +I+ + + +V YV DL M+ P VK + QLLRG+ ++H
Sbjct: 174 NIVLLHDII--HTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQ 231
Query: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
+ILHRDLK NLL+S G LK+ DFGLAR P Y+ VVT WYR P++LLG+ EY
Sbjct: 232 RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY 291
Query: 601 STAVDMWSVGCIFGELLTQKPLFPGNSEI-DQINKVFKELGTPSEKIWPGYSELPVVKKM 659
ST +DMW VGCIF E++ FPG +I DQ+ ++F LGTP+E WPG LP K
Sbjct: 292 STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE 351
Query: 660 TFSEHPYNNLRKRFGAL-LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 712
F+ + NLR+ + L + DL +K L P R+SA+ L HEYF + P
Sbjct: 352 RFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,043,959
Number of Sequences: 37866
Number of extensions: 1968031
Number of successful extensions: 134120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2612
Number of HSP's successfully gapped in prelim test: 1464
Number of HSP's that attempted gapping in prelim test: 18776
Number of HSP's gapped (non-prelim): 33158
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.