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Search of human proteins with 148763345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo
sapiens]
(770 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 1545 0.0
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 1532 0.0
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1521 0.0
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1514 0.0
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1513 0.0
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1445 0.0
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1441 0.0
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 1042 0.0
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 361 2e-99
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 312 9e-85
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 302 7e-82
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 298 1e-80
gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens] 290 5e-78
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 288 2e-77
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 270 4e-72
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 268 1e-71
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 253 6e-67
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 251 2e-66
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 246 6e-65
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 246 6e-65
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 246 8e-65
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 246 8e-65
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 242 8e-64
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 240 4e-63
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 239 9e-63
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 237 3e-62
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 237 3e-62
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 233 4e-61
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 229 1e-59
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 228 2e-59
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 1545 bits (4001), Expect = 0.0
Identities = 770/770 (100%), Positives = 770/770 (100%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 180
RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 180
Query: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240
ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV
Sbjct: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240
Query: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300
KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300
Query: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 360
EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 360
Query: 361 EAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIE 420
EAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIE
Sbjct: 361 EAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIE 420
Query: 421 EGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVV 480
EGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVV
Sbjct: 421 EGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVV 480
Query: 481 GSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKT 540
GSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKT
Sbjct: 481 GSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKT 540
Query: 541 SNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVG 600
SNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVG
Sbjct: 541 SNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVG 600
Query: 601 CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLR 660
CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLR
Sbjct: 601 CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLR 660
Query: 661 KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQ 720
KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQ
Sbjct: 661 KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQ 720
Query: 721 RVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
RVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 RVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 1532 bits (3967), Expect = 0.0
Identities = 769/780 (98%), Positives = 769/780 (98%), Gaps = 10/780 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------K 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 111 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 170
HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR
Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180
Query: 171 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 230
EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
Sbjct: 181 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 350
EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
Query: 351 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 410
RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV
Sbjct: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV 420
Query: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 470
EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
Query: 471 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 530
NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
Sbjct: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 540
Query: 531 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 590
NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY
Sbjct: 541 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
Query: 591 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 650
STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT
Sbjct: 601 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT 660
Query: 651 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 710
FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
Sbjct: 661 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF 720
Query: 711 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 780
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 1521 bits (3939), Expect = 0.0
Identities = 764/772 (98%), Positives = 765/772 (99%), Gaps = 3/772 (0%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKE--RE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK KHARVKE RE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 178
HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 179
Query: 179 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 238
QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK
Sbjct: 180 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 239
Query: 239 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 298
PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES
Sbjct: 240 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE
Sbjct: 300 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Query: 359 SEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNR 418
SEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNR
Sbjct: 360 SEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNR 419
Query: 419 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 478
IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI
Sbjct: 420 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 479
Query: 479 VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL 538
VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL
Sbjct: 480 VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL 539
Query: 539 KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWS 598
KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWS
Sbjct: 540 KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWS 599
Query: 599 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 658
VGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNN
Sbjct: 600 VGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNN 659
Query: 659 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE 718
LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE
Sbjct: 660 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE 719
Query: 719 QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 720 QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 771
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 1514 bits (3919), Expect = 0.0
Identities = 764/781 (97%), Positives = 765/781 (97%), Gaps = 12/781 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKE--RE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK KHARVKE RE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQLERKRERERKM 169
HERRKRHREEQDKARREWERQKRREMAREHSRRER DRLEQLERKRERERKM
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKM 179
Query: 170 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 229
REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE
Sbjct: 180 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE 239
Query: 230 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 289
RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE
Sbjct: 240 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 299
Query: 290 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 349
EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE
Sbjct: 300 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 359
Query: 350 SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRS 409
SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCRS
Sbjct: 360 SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRS 419
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
Query: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAKE
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599
Query: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 649
YSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKKM
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 659
Query: 650 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 709
TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 719
Query: 710 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK 769
FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK
Sbjct: 720 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK 779
Query: 770 F 770
F
Sbjct: 780 F 780
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 1513 bits (3916), Expect = 0.0
Identities = 763/782 (97%), Positives = 764/782 (97%), Gaps = 12/782 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK----------WK 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGK 120
Query: 111 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 168
HARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
Sbjct: 121 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK 180
Query: 169 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 228
MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
Sbjct: 181 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 240
Query: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288
ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
Sbjct: 241 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 300
Query: 289 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 348
EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP
Sbjct: 301 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 360
Query: 349 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR 408
ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCR
Sbjct: 361 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCR 420
Query: 409 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 468
SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ
Sbjct: 421 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 480
Query: 469 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 528
HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL
Sbjct: 481 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 540
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588
HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAK
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600
Query: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
EYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKK
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660
Query: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 708
MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 720
Query: 709 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 768
MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL
Sbjct: 721 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL 780
Query: 769 KF 770
KF
Sbjct: 781 KF 782
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 1445 bits (3741), Expect = 0.0
Identities = 726/738 (98%), Positives = 728/738 (98%), Gaps = 3/738 (0%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEKWKHARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
EKVHHRKDEKRKEK KHARVKE REHERRKRHREEQDKARREWERQKRREMAREHSRRE
Sbjct: 61 EKVHHRKDEKRKEK-KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 119
Query: 153 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 212
RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD
Sbjct: 120 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 179
Query: 213 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 272
KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA
Sbjct: 180 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 239
Query: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 332
ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM
Sbjct: 240 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 299
Query: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE 392
SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL PIE
Sbjct: 300 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIE 359
Query: 393 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 452
LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG
Sbjct: 360 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 419
Query: 453 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 512
FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG
Sbjct: 420 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 479
Query: 513 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 572
EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV
Sbjct: 480 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 539
Query: 573 VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 632
VVT WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQINKVFK+LGTP
Sbjct: 540 VVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP 599
Query: 633 SEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 692
SEKIWPGYSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG
Sbjct: 600 SEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 659
Query: 693 LKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHL 752
LKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHL
Sbjct: 660 LKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHL 719
Query: 753 TTTNQGASAAGPGFSLKF 770
TTTNQGASAAGPGFSLKF
Sbjct: 720 TTTNQGASAAGPGFSLKF 737
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 1441 bits (3730), Expect = 0.0
Identities = 726/748 (97%), Positives = 728/748 (97%), Gaps = 12/748 (1%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEK----------WKHARVKE--REHERRKRHREEQDKARREWERQKRR 142
EKVHHRKDEKRKEK KHARVKE REHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRR 120
Query: 143 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 202
EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH
Sbjct: 121 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 180
Query: 203 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 262
HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER
Sbjct: 181 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 240
Query: 263 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 322
KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ
Sbjct: 241 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 300
Query: 323 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 382
SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV
Sbjct: 301 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYV 360
Query: 383 PDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 442
PDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK
Sbjct: 361 PDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK 420
Query: 443 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 502
RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM
Sbjct: 421 RLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLM 480
Query: 503 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 562
ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY
Sbjct: 481 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 540
Query: 563 GSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQI 622
GSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG SEIDQI
Sbjct: 541 GSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQI 600
Query: 623 NKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 682
NKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF
Sbjct: 601 NKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYF 660
Query: 683 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 742
PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD
Sbjct: 661 PGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD 720
Query: 743 DDLKETGFHLTTTNQGASAAGPGFSLKF 770
DDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 721 DDLKETGFHLTTTNQGASAAGPGFSLKF 748
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 1042 bits (2694), Expect = 0.0
Identities = 521/526 (99%), Positives = 522/526 (99%)
Query: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 304
MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 305 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364
EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE
Sbjct: 61 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 120
Query: 365 EVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 424
EVGEGTPQSSALTEGDYVPDSPAL PIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY
Sbjct: 121 EVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTY 180
Query: 425 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 484
GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM
Sbjct: 181 GVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNM 240
Query: 485 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 544
DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL
Sbjct: 241 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 300
Query: 545 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 604
LSHAGILKVGDFGLAREYGSPLKAYTPVVVT WYRAPELLLGAKEYSTAVDMWSVGCIFG
Sbjct: 301 LSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFG 360
Query: 605 ELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFG 664
ELLTQKPLFPG SEIDQINKVFK+LGTPSEKIWPGYSELP VKKMTFSEHPYNNLRKRFG
Sbjct: 361 ELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFG 420
Query: 665 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 724
ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR
Sbjct: 421 ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKR 480
Query: 725 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 770
GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
Sbjct: 481 GTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF 526
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 361 bits (926), Expect = 2e-99
Identities = 175/327 (53%), Positives = 240/327 (73%), Gaps = 6/327 (1%)
Query: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 466
CRSV+EF+ LNRI EGTYG+VYRA+D +TDEIVALK+++M+KEK+G PI+SLREI +L+
Sbjct: 33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLR 92
Query: 467 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 526
+HPNIV ++E+VVG++++ I++VM Y E DL SL+E M PF +VK +++Q+LRG++
Sbjct: 93 LRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
Query: 527 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 586
+LH N+I+HRDLK SNLL++ G +K DFGLAR YG P+K TP VVT WYRAPELLLG
Sbjct: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
Query: 587 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVV 646
+T++DMW+VGCI ELL +PL PG SEI QI+ + + LGTPSE IWPG+S+LP+V
Sbjct: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272
Query: 647 KKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPID 706
+ + + PYNNL+ +F LS+ G L++ Y P +R +A D L+ YF+E PLP +
Sbjct: 273 GQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331
Query: 707 PSMFPTWPAKSEQQRVKRGTSPRPPEG 733
P + PT+P R KR +P EG
Sbjct: 332 PELMPTFP----HHRNKR-AAPATSEG 353
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 312 bits (799), Expect = 9e-85
Identities = 152/153 (99%), Positives = 152/153 (99%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEKWKHARVKEREHE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
RRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 302 bits (774), Expect = 7e-82
Identities = 147/288 (51%), Positives = 204/288 (70%), Gaps = 6/288 (2%)
Query: 446 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 505
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 506 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 565
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 566 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 625
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 626 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 685
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 686 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 733
R +A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 240 RATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 282
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 298 bits (764), Expect = 1e-80
Identities = 150/155 (96%), Positives = 150/155 (96%), Gaps = 2/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARV--KERE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
Score = 35.4 bits (80), Expect = 0.20
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 160 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 219
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
Query: 220 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 278
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
Query: 279 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 326
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
Score = 35.0 bits (79), Expect = 0.26
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 156 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 215
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
Query: 216 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 275
+PP++ ++EK R D +RK + E
Sbjct: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
Query: 276 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311
E + EE+++ E + E E E
Sbjct: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
>gi|237858580 cyclin-dependent kinase 10 isoform c [Homo sapiens]
Length = 283
Score = 290 bits (741), Expect = 5e-78
Identities = 144/288 (50%), Positives = 200/288 (69%), Gaps = 12/288 (4%)
Query: 446 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 505
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 506 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 565
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 566 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 625
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 626 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 685
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLF------ 233
Query: 686 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEG 733
+A D L+ YF+E PLP +P + PT+P R KR +P EG
Sbjct: 234 MATAGDCLESSYFKEKPLPCEPELMPTFP----HHRNKR-AAPATSEG 276
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 288 bits (736), Expect = 2e-77
Identities = 136/258 (52%), Positives = 189/258 (73%), Gaps = 1/258 (0%)
Query: 446 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETM 505
M+KEK+G PI+SLREI +L+ +HPNIV ++E+VVG++++ I++VM Y E DL SL+E M
Sbjct: 1 MDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENM 60
Query: 506 KQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 565
PF +VK +++Q+LRG+++LH N+I+HRDLK SNLL++ G +K DFGLAR YG P
Sbjct: 61 PTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVP 120
Query: 566 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 625
+K TP VVT WYRAPELLLG +T++DMW+VGCI ELL +PL PG SEI QI+ +
Sbjct: 121 VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLI 180
Query: 626 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 685
+ LGTPSE IWPG+S+LP+V + + + PYNNL+ +F LS+ G L++ Y P +
Sbjct: 181 VQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF-PWLSEAGLRLLHFLFMYDPKK 239
Query: 686 RISAEDGLKHEYFRETPL 703
R +A D L+ YF+E PL
Sbjct: 240 RATAGDCLESSYFKEKPL 257
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 270 bits (690), Expect = 4e-72
Identities = 135/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 528
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVT WYRAPE+LLG+K
Sbjct: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
Query: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
Y+TAVD+WS+GCIF E++T+K LFPG+SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Query: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 268 bits (686), Expect = 1e-71
Identities = 132/297 (44%), Positives = 201/297 (67%), Gaps = 5/297 (1%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+E FQ + +I EGTYGVVY+A++K T E+VALK+++++ E EG P T++REI+ + + H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 528
PNIV + +++ N K+Y+V ++ DLK M+ +P +K+ + QLL+G+
Sbjct: 61 PNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588
H + +LHRDLK NLL++ G +K+ DFGLAR +G P++ YT VVT WYRAPE+LLG K
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
Query: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
YSTAVD+WS+GCIF E++T++ LFPG+SEIDQ+ ++F+ LGTP E +WPG + +P K
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
Query: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 705
+F + + K L + G L+++ L Y P +RISA+ L H +F++ P+
Sbjct: 239 -SFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 253 bits (645), Expect = 6e-67
Identities = 123/297 (41%), Positives = 197/297 (66%), Gaps = 14/297 (4%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 523
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 583
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT VVT WYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEV 174
Query: 584 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 643
LLG+ YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 644 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 251 bits (640), Expect = 2e-66
Identities = 121/297 (40%), Positives = 196/297 (65%), Gaps = 14/297 (4%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+E++ + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 523
PNIV+++++++ + ++Y++ ++ DLK ++++ PG+ VK+ + Q+L+
Sbjct: 61 PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
Query: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 583
G+ H +LHRDLK NLL+ G +K+ DFGLAR +G P++ YT +T WYR+PE+
Sbjct: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
Query: 584 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 643
LLG+ YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP L
Sbjct: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
Query: 644 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
K TF + +L L + G DL++K L Y P +RIS + L H YF +
Sbjct: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 246 bits (628), Expect = 6e-65
Identities = 209/769 (27%), Positives = 332/769 (43%), Gaps = 81/769 (10%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRKDEKRKEKWKHARV----KEREHER------- 121
Q R K + R+ + + R + +ER
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 122 -------RKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQ 173
R+ RR + + R + HSR R R RL R R R +
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLS---RSRSRHSSISPST 442
Query: 174 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFEL 233
+ E ++ + EA R A ++ + + + P + E
Sbjct: 443 LTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTET 502
Query: 234 GDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGSEEEEEEEE 286
K VK+ K+E S + + + KT + + E+ ++ ++
Sbjct: 503 SASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAV 562
Query: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE--------EMSEDEER 338
+E ++ EE +E+ + T S + EQ V+ + ED+E
Sbjct: 563 IVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEA 622
Query: 339 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP------ALLPIE 392
++ + V + E E+ + P L GD + SP L +
Sbjct: 623 DSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSK 677
Query: 393 LKQEL--PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK 445
+ ++ P+Y + G R V++F + I EGTYG VY+A+DK T E+VALK+++
Sbjct: 678 RRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737
Query: 446 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHD 497
++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+V Y++HD
Sbjct: 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHD 797
Query: 498 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 557
L L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G +K+ DFG
Sbjct: 798 LMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFG 857
Query: 558 LAREYGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 616
LAR Y S + YT V+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N
Sbjct: 858 LARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 917
Query: 617 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 676
E+ Q+ + + G+P +WP +LP M + LR+ F + DL +
Sbjct: 918 QELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFD 976
Query: 677 KFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 724
L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 977 YMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 33.5 bits (75), Expect = 0.77
Identities = 52/242 (21%), Positives = 82/242 (33%), Gaps = 41/242 (16%)
Query: 139 QKRREMAREHSRRERDRLEQLERKRERERKMREQQK---EQREQKERERRAEERRKE--- 192
Q+R E + RR+R ++R RE + R+ Q+ E + + R + E R E
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 193 ---------REARREVSAHHRTMREDYSDKVKASHW--SRSPP----RPPRERFELGDGR 237
R ++ + R+D K S S+ PP PP+ E D
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYRE--DKT 305
Query: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 297
+P + L D S R + S S + S +G GS+
Sbjct: 306 EPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG-------------GSSPYS 352
Query: 298 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 357
+ S S +S + +VS S R + + P S R SG
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYSPVLRRSG 407
Query: 358 ES 359
+S
Sbjct: 408 KS 409
Score = 30.8 bits (68), Expect = 5.0
Identities = 39/172 (22%), Positives = 63/172 (36%), Gaps = 22/172 (12%)
Query: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE 135
RGE + + + S + K HR + +R++ + + R EE+ + +
Sbjct: 190 RGEGSERRPRRDRRSSSGRSKERHR-EHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 136 WE------RQKRREMAREHSRRERDRLEQLERKRERERK-----MREQQKEQREQKERER 184
R+K S +DR + R R + K +E K RE K E
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK-TEP 307
Query: 185 RAEERRKERE---ARREVSAHHRTMREDYSDKVK------ASHWSRSPPRPP 227
+A RR+ R + HR + S K +S +SR PR P
Sbjct: 308 KAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP 359
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 246 bits (628), Expect = 6e-65
Identities = 209/769 (27%), Positives = 332/769 (43%), Gaps = 81/769 (10%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
RK+++ KA R K+S + S + D YRR S+ G DDS
Sbjct: 271 RKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKT-----EPKAYRRRRSLSPLGGRDDS 325
Query: 83 LAIKPPQQMSRKEKV----------HHRKDEKRKEKWKHARV----KEREHER------- 121
Q R K + R+ + + R + +ER
Sbjct: 326 PVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPS 385
Query: 122 -------RKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQ 173
R+ RR + + R + HSR R R RL R R R +
Sbjct: 386 PYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHSRSRSRHRLS---RSRSRHSSISPST 442
Query: 174 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFEL 233
+ E ++ + EA R A ++ + + + P + E
Sbjct: 443 LTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTET 502
Query: 234 GDGR------KPVKEEKMEERDLLSDLQDISDSERKTSSA-ESSSAESGSGSEEEEEEEE 286
K VK+ K+E S + + + KT + + E+ ++ ++
Sbjct: 503 SASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAV 562
Query: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE--------EMSEDEER 338
+E ++ EE +E+ + T S + EQ V+ + ED+E
Sbjct: 563 IVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEA 622
Query: 339 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP------ALLPIE 392
++ + V + E E+ + P L GD + SP L +
Sbjct: 623 DSLRGNISVKAVK-----KEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSK 677
Query: 393 LKQEL--PKYLPALQ-----GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK 445
+ ++ P+Y + G R V++F + I EGTYG VY+A+DK T E+VALK+++
Sbjct: 678 RRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737
Query: 446 MEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHD 497
++ EKEGFPIT++REI + + H +I+ ++EIV DK Y+V Y++HD
Sbjct: 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHD 797
Query: 498 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 557
L L+E+ F +K+ M QL+ G+ + H LHRD+K SN+LL++ G +K+ DFG
Sbjct: 798 LMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFG 857
Query: 558 LAREYGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 616
LAR Y S + YT V+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N
Sbjct: 858 LARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQAN 917
Query: 617 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 676
E+ Q+ + + G+P +WP +LP M + LR+ F + DL +
Sbjct: 918 QELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFD 976
Query: 677 KFLTYFPGRRISAEDGLKHEYFRET-PLPIDPSMFPTWPAKSEQQRVKR 724
L P +R +AE L+ E+ R+ P + P P W E KR
Sbjct: 977 YMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 1025
Score = 33.5 bits (75), Expect = 0.77
Identities = 52/242 (21%), Positives = 82/242 (33%), Gaps = 41/242 (16%)
Query: 139 QKRREMAREHSRRERDRLEQLERKRERERKMREQQK---EQREQKERERRAEERRKE--- 192
Q+R E + RR+R ++R RE + R+ Q+ E + + R + E R E
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAK 247
Query: 193 ---------REARREVSAHHRTMREDYSDKVKASHW--SRSPP----RPPRERFELGDGR 237
R ++ + R+D K S S+ PP PP+ E D
Sbjct: 248 SGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYRE--DKT 305
Query: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 297
+P + L D S R + S S + S +G GS+
Sbjct: 306 EPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG-------------GSSPYS 352
Query: 298 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 357
+ S S +S + +VS S R + + P S R SG
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRS-----PYSPVLRRSG 407
Query: 358 ES 359
+S
Sbjct: 408 KS 409
Score = 30.8 bits (68), Expect = 5.0
Identities = 39/172 (22%), Positives = 63/172 (36%), Gaps = 22/172 (12%)
Query: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE 135
RGE + + + S + K HR + +R++ + + R EE+ + +
Sbjct: 190 RGEGSERRPRRDRRSSSGRSKERHR-EHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKS 248
Query: 136 WE------RQKRREMAREHSRRERDRLEQLERKRERERK-----MREQQKEQREQKERER 184
R+K S +DR + R R + K +E K RE K E
Sbjct: 249 GSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK-TEP 307
Query: 185 RAEERRKERE---ARREVSAHHRTMREDYSDKVK------ASHWSRSPPRPP 227
+A RR+ R + HR + S K +S +SR PR P
Sbjct: 308 KAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP 359
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 358 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 404
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 405 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 462
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 463 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 514
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 515 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 573
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 574 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 633
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 634 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 693
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 694 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 726
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 727 -------SPRPPEGGLGYSQLGDDD 744
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 40.0 bits (92), Expect = 0.008
Identities = 59/301 (19%), Positives = 106/301 (35%), Gaps = 27/301 (8%)
Query: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
E RL + R + S + G + + T+ +D D D +A K
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFK--- 90
Query: 90 QMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR-REWERQKRREMAREH 148
+ R+E R ++ KH R +HR +D + ++ E++K +E++ +
Sbjct: 91 -LDRRENDERRGSDRSDRLHKH---------RHHQHRRSRDLLKAKQTEKEKSQEVSSK- 139
Query: 149 SRRERDRLEQLERKRERER----KMREQQKEQREQKERERRAEERRKEREAR-----REV 199
S +DR+ ++ E K + + +E + + E+ RKERE + R
Sbjct: 140 SGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSK 199
Query: 200 SAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259
S R + Y SRSP R + + D P ++ DL S
Sbjct: 200 SHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD--SPSGASYGQDYDLSPSRSHTSS 257
Query: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319
+ + S++ S S +E + S S S + + S
Sbjct: 258 NYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSG 317
Query: 320 S 320
S
Sbjct: 318 S 318
Score = 38.9 bits (89), Expect = 0.018
Identities = 52/231 (22%), Positives = 90/231 (38%), Gaps = 31/231 (13%)
Query: 75 DRGEEDDSLAIKPPQQMSRKEKVHHRKDE-----KRKEKWKHARV-------KEREHERR 122
DR E D+ ++ + HR+ K+ EK K V K+R
Sbjct: 92 DRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 123 KRHREEQDK------ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 176
KR EE D A+ + + ++ +E +R+ER+ L+ + R + + RE K
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE-LKSGHKDRSKSHRKRETPKSY 210
Query: 177 R--EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERF 231
+ + +R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 211 KTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTS 270
Query: 232 ELGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 275
P KE + S + +S S R++SS E S + SG
Sbjct: 271 RRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 246 bits (627), Expect = 8e-65
Identities = 153/445 (34%), Positives = 228/445 (51%), Gaps = 59/445 (13%)
Query: 358 ESEEAEEEVGEGTPQSSALTEGDYVP-DSPALLPIELKQELPKYLPAL------------ 404
E E+ + P L GD P DSP I Q+ K P +
Sbjct: 657 EKEQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTE 716
Query: 405 --QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 462
G R V++F + I EGTYG VY+AKDK T E+VALK+++++ EKEGFPIT++REI
Sbjct: 717 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIK 776
Query: 463 TILKAQHPNIVTVREIVVGSN------MDK--IYIVMNYVEHDLKSLMETMKQPFLPGEV 514
+ + H ++V ++EIV DK Y+V Y++HDL L+E+ F +
Sbjct: 777 ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836
Query: 515 KTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVV 573
K+ M QL+ G+++ H LHRD+K SN+LL+++G +K+ DFGLAR Y S + YT V
Sbjct: 837 KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896
Query: 574 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 633
+T WYR PELLLG + Y+ A+D+WS GCI GEL T+KP+F N E+ Q+ + + G+P
Sbjct: 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956
Query: 634 EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGL 693
+WP +LP M + LR+ F + + DL++ LT P +R +AE L
Sbjct: 957 PAVWPDVIKLPYFNTMKPKKQYRRRLREEF-SFIPSAALDLLDHMLTLDPSKRCTAEQTL 1015
Query: 694 KHEYFRETPL-PIDPSMFPTW-------------------------PAKSEQQRVKRGT- 726
+ ++ ++ L + P P W P+K+ ++ GT
Sbjct: 1016 QSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTS 1075
Query: 727 -------SPRPPEGGLGYSQLGDDD 744
SP PP+ G + G D
Sbjct: 1076 TEPVKNSSPAPPQPAPGKVESGAGD 1100
Score = 40.0 bits (92), Expect = 0.008
Identities = 59/301 (19%), Positives = 106/301 (35%), Gaps = 27/301 (8%)
Query: 31 EIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
E RL + R + S + G + + T+ +D D D +A K
Sbjct: 34 ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFK--- 90
Query: 90 QMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR-REWERQKRREMAREH 148
+ R+E R ++ KH R +HR +D + ++ E++K +E++ +
Sbjct: 91 -LDRRENDERRGSDRSDRLHKH---------RHHQHRRSRDLLKAKQTEKEKSQEVSSK- 139
Query: 149 SRRERDRLEQLERKRERER----KMREQQKEQREQKERERRAEERRKEREAR-----REV 199
S +DR+ ++ E K + + +E + + E+ RKERE + R
Sbjct: 140 SGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSK 199
Query: 200 SAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259
S R + Y SRSP R + + D P ++ DL S
Sbjct: 200 SHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDD--SPSGASYGQDYDLSPSRSHTSS 257
Query: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319
+ + S++ S S +E + S S S + + S
Sbjct: 258 NYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSG 317
Query: 320 S 320
S
Sbjct: 318 S 318
Score = 38.9 bits (89), Expect = 0.018
Identities = 52/231 (22%), Positives = 90/231 (38%), Gaps = 31/231 (13%)
Query: 75 DRGEEDDSLAIKPPQQMSRKEKVHHRKDE-----KRKEKWKHARV-------KEREHERR 122
DR E D+ ++ + HR+ K+ EK K V K+R
Sbjct: 92 DRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSS 151
Query: 123 KRHREEQDK------ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 176
KR EE D A+ + + ++ +E +R+ER+ L+ + R + + RE K
Sbjct: 152 KRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERE-LKSGHKDRSKSHRKRETPKSY 210
Query: 177 R--EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR---SPPRPPRERF 231
+ + +R R+ R+ ++++ S + +DY SH S S + P
Sbjct: 211 KTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTS 270
Query: 232 ELGDGRKPVKEEKMEERDLLSD------LQDISD-SERKTSSAESSSAESG 275
P KE + S + +S S R++SS E S + SG
Sbjct: 271 RRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSG 321
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 242 bits (618), Expect = 8e-64
Identities = 130/336 (38%), Positives = 200/336 (59%), Gaps = 16/336 (4%)
Query: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 467
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 468 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 527
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
Query: 528 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 587
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT+WYRAPELL GA
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
Query: 588 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 647
+ Y VDMW+VGCI ELL + P PG+S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
Query: 648 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 707
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
Query: 708 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 735
P P ++ +++ +KR + +GGL
Sbjct: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 240 bits (612), Expect = 4e-63
Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI + + +H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
NIV + +++ K+ +V + + DLK ++ P VK+ + QLL+G+ H
Sbjct: 61 KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
Query: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
+LHRDLK NLL++ G LK+ DFGLAR +G P++ Y+ VVT WYR P++L GAK
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 590 YSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
YST++DMWS GCIF EL +PLFPGN DQ+ ++F+ LGTP+E+ WP ++LP K
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
Query: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
+ +P L+ G DL+ L P +RISAE+ L+H YF +
Sbjct: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 239 bits (609), Expect = 9e-63
Identities = 124/295 (42%), Positives = 183/295 (62%), Gaps = 6/295 (2%)
Query: 406 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTIL 465
G +E + L ++ EGTY VY+ + K T+ +VALK +++E E EG P T++RE++ +
Sbjct: 185 GFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLK 243
Query: 466 KAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRG 524
+H NIVT+ +IV + DK + +V Y++ DLK M+ VK + Q+LRG
Sbjct: 244 DLKHANIVTLHDIV---HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG 300
Query: 525 VKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 584
+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+ VVT WYR P++L
Sbjct: 301 LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL 360
Query: 585 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELP 644
LG+ EYST +DMW VGCIF E+ + +PLFPG++ D+++ +F+ LGTPS++ WPG S
Sbjct: 361 LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE 420
Query: 645 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 699
K F ++ L L +G +L+ KFL Y +R+SAE+ +KH YFR
Sbjct: 421 EFKNYNFPKYKPQPLINH-APRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFR 474
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 237 bits (604), Expect = 3e-62
Identities = 156/460 (33%), Positives = 235/460 (51%), Gaps = 19/460 (4%)
Query: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 332
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 41 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 100
Query: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE 392
S R + + S D + S A+ + EG + LT + D P
Sbjct: 101 SPVRVRMRNHPPRKI--STEDINKRLSLPADIRLPEGYLEK--LTLNSPIFDKP------ 150
Query: 393 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 452
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E EG
Sbjct: 151 LSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EG 209
Query: 453 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 512
P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 210 APCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMH 267
Query: 513 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 572
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+
Sbjct: 268 NVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNE 327
Query: 573 VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 632
VVT WYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG++ +Q++ +F+ LGTP
Sbjct: 328 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 387
Query: 633 SEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 692
+E+ WPG K + ++ L L SD G DL+ K L + RISAED
Sbjct: 388 TEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISAEDA 446
Query: 693 LKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 727
+KH +F R LP S+F + +++ R +S
Sbjct: 447 MKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 486
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 237 bits (604), Expect = 3e-62
Identities = 156/460 (33%), Positives = 235/460 (51%), Gaps = 19/460 (4%)
Query: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 332
ESG G + E G E E+ S+ S+Q++ S+E
Sbjct: 35 ESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQ 94
Query: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE 392
S R + + S D + S A+ + EG + LT + D P
Sbjct: 95 SPVRVRMRNHPPRKI--STEDINKRLSLPADIRLPEGYLEK--LTLNSPIFDKP------ 144
Query: 393 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEG 452
L + L + + G +E + L+++ EGTY VY+ K K TD +VALK +++E E EG
Sbjct: 145 LSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EG 203
Query: 453 FPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG 512
P T++RE++ + +H NIVT+ +I+ + +V Y++ DLK ++
Sbjct: 204 APCTAIREVSLLKDLKHANIVTLHDII--HTEKSLTLVFEYLDKDLKQYLDDCGNIINMH 261
Query: 513 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPV 572
VK + QLLRG+ + H +LHRDLK NLL++ G LK+ DFGLAR P K Y+
Sbjct: 262 NVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNE 321
Query: 573 VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP 632
VVT WYR P++LLG+ +YST +DMW VGCIF E+ T +PLFPG++ +Q++ +F+ LGTP
Sbjct: 322 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 381
Query: 633 SEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 692
+E+ WPG K + ++ L L SD G DL+ K L + RISAED
Sbjct: 382 TEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSD-GADLLTKLLQFEGRNRISAEDA 440
Query: 693 LKHEYF-----RETPLPIDPSMFPTWPAKSEQQRVKRGTS 727
+KH +F R LP S+F + +++ R +S
Sbjct: 441 MKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS 480
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 233 bits (595), Expect = 4e-61
Identities = 126/303 (41%), Positives = 185/303 (61%), Gaps = 3/303 (0%)
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
++++ L RI EG +G+V++AK +T EIVALK++ + + ++GFP +LREI L+
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKA-LQEME 59
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
N V+ V + + ++ DL ++ ++P +VK+ + LL+GV H
Sbjct: 60 DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP-LKAYTPVVVTQWYRAPELLLGAK 588
N I+HRDLK +NLL+S +G LK+ DFGLAR + + YT V T+WYRAPELL GA+
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
+Y VD+WSVGCI GELL PLFPG ++I+Q+ V + LGTP+ ++WP +ELP K
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS 708
++F E L + +S Q DL+ +FL Y P +RI+A L H+YF PLP PS
Sbjct: 240 ISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS 298
Query: 709 MFP 711
P
Sbjct: 299 ELP 301
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 229 bits (583), Expect = 1e-59
Identities = 117/311 (37%), Positives = 183/311 (58%), Gaps = 11/311 (3%)
Query: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 466
C V +++ L +I +GT+G V++A+ +KT + VALK++ ME EKEGFPIT+LREI +
Sbjct: 13 CDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQL 72
Query: 467 AQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 520
+H N+V + EI IY+V ++ EHDL L+ + F E+K +M
Sbjct: 73 LKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQM 132
Query: 521 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG----SPLKAYTPVVVTQ 576
LL G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + S YT VVT
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTL 192
Query: 577 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 636
WYR PELLLG ++Y +D+W GCI E+ T+ P+ GN+E Q+ + + G+ + ++
Sbjct: 193 WYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEV 252
Query: 637 WPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKH 695
WP + +K+ + ++ R A + D DL++K L P +RI ++D L H
Sbjct: 253 WPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNH 312
Query: 696 EYFRETPLPID 706
++F P+P D
Sbjct: 313 DFFWSDPMPSD 323
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 228 bits (580), Expect = 2e-59
Identities = 121/294 (41%), Positives = 175/294 (59%), Gaps = 5/294 (1%)
Query: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 470
+ ++ L ++ EG+Y VY+ K K ++VALK +++++E EG P T++RE + + +H
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHA 173
Query: 471 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD 530
NIV + +I+ + + +V YV DL M+ P VK + QLLRG+ ++H
Sbjct: 174 NIVLLHDII--HTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQ 231
Query: 531 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 590
+ILHRDLK NLL+S G LK+ DFGLAR P Y+ VVT WYR P++LLG+ EY
Sbjct: 232 RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY 291
Query: 591 STAVDMWSVGCIFGELLTQKPLFPGNSEI-DQINKVFKELGTPSEKIWPGYSELPVVKKM 649
ST +DMW VGCIF E++ FPG +I DQ+ ++F LGTP+E WPG LP K
Sbjct: 292 STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE 351
Query: 650 TFSEHPYNNLRKRFGAL-LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 702
F+ + NLR+ + L + DL +K L P R+SA+ L HEYF + P
Sbjct: 352 RFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,506,478
Number of Sequences: 37866
Number of extensions: 1936638
Number of successful extensions: 136038
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2629
Number of HSP's successfully gapped in prelim test: 1492
Number of HSP's that attempted gapping in prelim test: 18680
Number of HSP's gapped (non-prelim): 33572
length of query: 770
length of database: 18,247,518
effective HSP length: 110
effective length of query: 660
effective length of database: 14,082,258
effective search space: 9294290280
effective search space used: 9294290280
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.