Search of human proteins with 148664242

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
sapiens]
         (1235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...  2534   0.0  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...  2504   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]          1735   0.0  
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...  1722   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]       1508   0.0  
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...  1256   0.0  
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...  1217   0.0  
gi|4505463 contactin associated protein 1 precursor [Homo sapiens]    882   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...   740   0.0  
gi|239743729 PREDICTED: similar to contactin associated protein-...   448   e-125
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   336   9e-92
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...   193   1e-48
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             119   1e-26
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       116   1e-25
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       116   1e-25
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       114   4e-25
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        114   4e-25
gi|239752499 PREDICTED: similar to cell recognition molecule Cas...   107   5e-23
gi|105990535 coagulation factor V precursor [Homo sapiens]             86   2e-16
gi|54873613 agrin [Homo sapiens]                                       82   3e-15
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...    81   7e-15
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...    80   1e-14
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    80   1e-14
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]            79   2e-14
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...    79   3e-14
gi|62420886 discoidin domain receptor family, member 2 precursor...    75   5e-13
gi|62420884 discoidin domain receptor family, member 2 precursor...    75   5e-13
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    74   1e-12
gi|33469935 EGF-like, fibronectin type III and laminin G domains...    74   1e-12
gi|33469931 EGF-like, fibronectin type III and laminin G domains...    74   1e-12

>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 2534 bits (6569), Expect = 0.0
 Identities = 1235/1235 (100%), Positives = 1235/1235 (100%)

Query: 1    MWNYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDL 60
            MWNYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDL
Sbjct: 1    MWNYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDL 60

Query: 61   GERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYR 120
            GERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYR
Sbjct: 61   GERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYR 120

Query: 121  LQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIK 180
            LQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIK
Sbjct: 121  LQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIK 180

Query: 181  DIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGS 240
            DIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGS
Sbjct: 181  DIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGS 240

Query: 241  LLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEGNVSFSCSQPQSMPVT 300
            LLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEGNVSFSCSQPQSMPVT
Sbjct: 241  LLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEGNVSFSCSQPQSMPVT 300

Query: 301  FLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLY 360
            FLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLY
Sbjct: 301  FLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLY 360

Query: 361  QPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYF 420
            QPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYF
Sbjct: 361  QPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYF 420

Query: 421  GGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRC 480
            GGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRC
Sbjct: 421  GGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRC 480

Query: 481  LPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDG 540
            LPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDG
Sbjct: 481  LPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDG 540

Query: 541  SGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRA 600
            SGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRA
Sbjct: 541  SGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRA 600

Query: 601  EHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDS 660
            EHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDS
Sbjct: 601  EHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDS 660

Query: 661  QYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWN 720
            QYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWN
Sbjct: 661  QYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWN 720

Query: 721  SASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFS 780
            SASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFS
Sbjct: 721  SASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFS 780

Query: 781  FDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN 840
            FDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN
Sbjct: 781  FDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN 840

Query: 841  SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG 900
            SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG
Sbjct: 841  SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG 900

Query: 901  KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHG 960
            KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHG
Sbjct: 901  KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHG 960

Query: 961  DMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNF 1020
            DMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNF
Sbjct: 961  DMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNF 1020

Query: 1021 DFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVD 1080
            DFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVD
Sbjct: 1021 DFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVD 1080

Query: 1081 QDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSR 1140
            QDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSR
Sbjct: 1081 QDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSR 1140

Query: 1141 ERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKR 1200
            ERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKR
Sbjct: 1141 ERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKR 1200

Query: 1201 SEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF 1235
            SEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF
Sbjct: 1201 SEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF 1235


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
          Length = 1308

 Score = 2504 bits (6489), Expect = 0.0
 Identities = 1232/1281 (96%), Positives = 1233/1281 (96%), Gaps = 48/1281 (3%)

Query: 3    NYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 62
            +YDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE
Sbjct: 28   SYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 87

Query: 63   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 122
            RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ
Sbjct: 88   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 147

Query: 123  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 182
            PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI
Sbjct: 148  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 207

Query: 183  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 242
            ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL
Sbjct: 208  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 267

Query: 243  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE------------------ 284
            DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE                  
Sbjct: 268  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHR 327

Query: 285  ------------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFS 314
                                          GNVSFSCSQPQSMPVTFLSSRSYLALPDFS
Sbjct: 328  NFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFS 387

Query: 315  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 374
            GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE
Sbjct: 388  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 447

Query: 375  LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 434
            LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS
Sbjct: 448  LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 507

Query: 435  PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 494
            PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS
Sbjct: 508  PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 567

Query: 495  WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 554
            WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT
Sbjct: 568  WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 627

Query: 555  ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 614
            ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS
Sbjct: 628  ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 687

Query: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674
            RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT
Sbjct: 688  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 747

Query: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734
            NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP
Sbjct: 748  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 807

Query: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794
            TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS
Sbjct: 808  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 867

Query: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854
            PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG
Sbjct: 868  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 927

Query: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914
            FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT
Sbjct: 928  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 987

Query: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 974
            FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR
Sbjct: 988  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 1047

Query: 975  TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1034
            TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM
Sbjct: 1048 TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1107

Query: 1035 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1094
            INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC
Sbjct: 1108 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1167

Query: 1095 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID 1154
            LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID
Sbjct: 1168 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID 1227

Query: 1155 DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA 1214
            DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA
Sbjct: 1228 DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA 1287

Query: 1215 VLKSELNIQNAVNENQKEYFF 1235
            VLKSELNIQNAVNENQKEYFF
Sbjct: 1288 VLKSELNIQNAVNENQKEYFF 1308


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 1735 bits (4494), Expect = 0.0
 Identities = 855/1257 (68%), Positives = 989/1257 (78%), Gaps = 56/1257 (4%)

Query: 5    DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64
            DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 30   DCDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89

Query: 65   EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124
            EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 90   EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149

Query: 125  IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184
             +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLYR D+K L PI+D+IS
Sbjct: 150  FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYRLDKKPLKPIRDVIS 209

Query: 185  LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244
            LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 210  LKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269

Query: 245  QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE-------------------- 284
            QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E                    
Sbjct: 270  QHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSYLDLNFEISFGGIPTPGRSRAFRRKSF 329

Query: 285  ----------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 316
                                        GNVSFSC QPQ++PVTFLSSRSYLALP  SGE
Sbjct: 330  HGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGE 389

Query: 317  EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELN 376
            ++VS TFQFRTWN+AG LLF EL+  SG  +LFL DGKLK +L+QPG+ P ++TAG  LN
Sbjct: 390  DKVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDGKLKLSLFQPGQSPRNVTAGAGLN 449

Query: 377  DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436
            DGQWHSVS SAK +H++V VD   A   PL+    I SG TYYFGGC D S GS CKSPL
Sbjct: 450  DGQWHSVSFSAKWSHMNVVVDDDTA-VQPLVAV-LIDSGDTYYFGGCLDNSSGSGCKSPL 507

Query: 437  GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496
            GGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP+YCEHGGECSQSW 
Sbjct: 508  GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 567

Query: 497  TFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT-E 555
            TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSGPL PFL+YCNMT +
Sbjct: 568  TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTAD 627

Query: 556  TAWTIIQHNGSDLTRVRNTNPENPYAGF-FEYVASMEQLQATINRAEHCEQEFTYYCKKS 614
             AWT++QH G D   +R     +P +   F Y A   QL++ +N AE CEQ     C  +
Sbjct: 628  AAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYAAGAGQLRSAVNLAERCEQRLALRCGTA 687

Query: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674
            R  + +DGTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA RNEWT
Sbjct: 688  RRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWT 747

Query: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734
            +DT +L+ KEHLPVT+IV+TD GR HSEAAY LGPLLC+GD+SFWNSASF+TE SYLHFP
Sbjct: 748  SDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFP 807

Query: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794
             FHGEL+ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQS
Sbjct: 808  AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS 867

Query: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854
            PT FNDNQWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+GGTATRQRG
Sbjct: 868  PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 927

Query: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914
            FLGCIRSLQLNG+ LDLEERA VTP V+PGC GHCS+YG LCRNGG+CRE+  G  CDC 
Sbjct: 928  FLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 987

Query: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 974
            FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFR
Sbjct: 988  FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFR 1047

Query: 975  TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1034
            TTRTPSLLL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + 
Sbjct: 1048 TTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK 1107

Query: 1035 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1094
            INREE VV +E++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGC
Sbjct: 1108 INREEAVVMVEVNQSTKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGC 1167

Query: 1095 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHS 1150
            LSAV+    APLKAAL PS P  VTV GHV   + C A   + + +RE   R    A  S
Sbjct: 1168 LSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRS 1227

Query: 1151 GTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
            G  D+ EPL NA + DSAVIGG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1228 GPADEGEPLVNADRRDSAVIGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
            [Homo sapiens]
          Length = 1288

 Score = 1722 bits (4461), Expect = 0.0
 Identities = 848/1257 (67%), Positives = 988/1257 (78%), Gaps = 56/1257 (4%)

Query: 5    DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64
            DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 30   DCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89

Query: 65   EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124
            EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 90   EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149

Query: 125  IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184
             +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLY  D+K L PI+D+IS
Sbjct: 150  FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVIS 209

Query: 185  LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244
            LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 210  LKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269

Query: 245  QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE-------------------- 284
            QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E                    
Sbjct: 270  QHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSF 329

Query: 285  ----------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 316
                                        GNVSFSC QPQ++PVTFLSSRSYLALP  SGE
Sbjct: 330  HGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGE 389

Query: 317  EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELN 376
            ++VS TFQFRTWN+AG LLF ELQ  SG  +LFL DGKLK +L+Q G+ P ++TAG  LN
Sbjct: 390  DKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLN 449

Query: 377  DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436
            DGQWHSVS SAK +H++V VD   A   PL+    I SG TYYFGGC   S GS CKSPL
Sbjct: 450  DGQWHSVSFSAKWSHMNVVVDDDTA-VQPLVAV-LIDSGDTYYFGGCLGNSSGSGCKSPL 507

Query: 437  GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496
            GGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP+YCEHGGECSQSW 
Sbjct: 508  GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 567

Query: 497  TFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT-E 555
            TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSGPL PFL+YCNMT +
Sbjct: 568  TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTAD 627

Query: 556  TAWTIIQHNGSDLTRVRNTNPENPYAGF-FEYVASMEQLQATINRAEHCEQEFTYYCKKS 614
            +AWT+++H G D   +R     +P +   F Y A   QL+A +N AE CEQ     C  +
Sbjct: 628  SAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTA 687

Query: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674
            R  + +DGTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA +NEWT
Sbjct: 688  RRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWT 747

Query: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734
            +DT +L+ KEHLPVT+IV+TDTG+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP
Sbjct: 748  SDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFP 807

Query: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794
             FHGEL+ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQS
Sbjct: 808  AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS 867

Query: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854
            PT FNDNQWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+GGTATRQRG
Sbjct: 868  PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 927

Query: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914
            FLGCIRSLQLNG+ LDLEERA VTP V+PGC GHCS+YG LCRNGG+CRE+  G  CDC 
Sbjct: 928  FLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 987

Query: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 974
            FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFR
Sbjct: 988  FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFR 1047

Query: 975  TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1034
            TTR+PSLLL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + 
Sbjct: 1048 TTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK 1107

Query: 1035 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1094
            INREE VV +E++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGC
Sbjct: 1108 INREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGC 1167

Query: 1095 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHS 1150
            LSAV+    APLKAAL PS P  VTV GHV   + C A   + + +RE   R    A  S
Sbjct: 1168 LSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRS 1227

Query: 1151 GTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
            G +D+ EPL NA + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1228 GPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 1508 bits (3903), Expect = 0.0
 Identities = 727/1282 (56%), Positives = 937/1282 (73%), Gaps = 53/1282 (4%)

Query: 3    NYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 62
            NY+CDDPL S L   +FSSSS+L+ +H P  A+LN R G GGWSP  SN  QWLQ+DLG 
Sbjct: 27   NYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWSPADSNAQQWLQMDLGN 84

Query: 63   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 122
            R+E+TAVATQG YGSS+WVTSY LMFSD+G NWKQY+QEDSIW F+GN NADSVV+++L 
Sbjct: 85   RVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHKLL 144

Query: 123  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 182
             S++ARF+RF+PLEWNP G+IGMR+EV+GC+Y+S+V D DG+SSLLYRF+QK +S +KD+
Sbjct: 145  HSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDV 204

Query: 183  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 242
            ISLKFK+MQ DG+L H EG  GDHITL+L++ RL L +N G++K   +S+L + TLGSLL
Sbjct: 205  ISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLL 264

Query: 243  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE------------------ 284
            DDQHWHSVLI+R+GKQVNFTVD+H  HF  +GE + +++DYE                  
Sbjct: 265  DDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKK 324

Query: 285  -----------------------------GNVSFSCSQPQSMPVTFL-SSRSYLALPDFS 314
                                         GNV+FSCS+PQ +P+TF+ SS SYL LP   
Sbjct: 325  NFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTP 384

Query: 315  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 374
              + +S +FQFRTWNK GLLL +EL   SG +LL L  G L+  + +  +  ++I  G  
Sbjct: 385  QIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSN 444

Query: 375  LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 434
            LNDG WHSVS++A++N +++ +D + A  AP     QIYSG +YYFGGCPD    S+C +
Sbjct: 445  LNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLN 504

Query: 435  PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 494
            P+  FQGCMRLI I  +  DLISVQQGSLGNFSDL ID C I DRCLPNYCEHGG CSQS
Sbjct: 505  PIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQS 564

Query: 495  WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 554
            W+TF+CNC++T Y GATCHNSIYEQSCE Y+H+GNT+GF+YIDSDGSGPL P  +YCN+T
Sbjct: 565  WTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVYCNIT 624

Query: 555  ETA-WTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKK 613
            E   WT +QHN ++LTRVR  NPE PYA   +Y  SMEQL+A I+ +EHCEQE  Y+C++
Sbjct: 625  EDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQEVAYHCRR 684

Query: 614  SRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEW 673
            SRL+N  DGTP +WW+GR+NE   YWGGS P +Q+C CGL+ +C+D Q++CNCDAD++EW
Sbjct: 685  SRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEW 744

Query: 674  TNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHF 733
            TNDTG L++K+HLPVT+IVITDT R +SEAA+++GPL C GDR FWN+ SF TEASYLHF
Sbjct: 745  TNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHF 804

Query: 734  PTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQ 793
            PTFH E SAD+SFFFKTTA SGVFLENLGI DFIR+E+ SP+ +TF+ DVGNGP E+ VQ
Sbjct: 805  PTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQ 864

Query: 794  SPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR 853
            SP+  NDNQWH+VR ERN+KE SLQVD L   T+    +GH  LQLNSQLFVGGT++RQ+
Sbjct: 865  SPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQK 924

Query: 854  GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDC 913
            GFLGCIRSL LNG  +DLEERA+VT  V+PGC GHCSSYG +C NGGKC E+  G+ CDC
Sbjct: 925  GFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDC 984

Query: 914  TFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSF 973
            T S Y GPFC  E+SA F +G+SV Y FQE Y ++KN S  +++ + D   S+E I  SF
Sbjct: 985  TNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSF 1044

Query: 974  RTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHI 1033
             TT+ PSLLLF++S  ++++ V++ KNGSLQ+RY LNK +E  V   D  N A+ ++HH+
Sbjct: 1045 VTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNK-EETHVFTIDADNFANRRMHHL 1103

Query: 1034 MINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTG 1093
             INRE   + I++D   R   + S   EF  ++SL LG++ E+  +D + A A A GF G
Sbjct: 1104 KINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAG 1163

Query: 1094 CLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTI 1153
            C+S+VQ +H+APLKAAL  +   PVTV G +TESSC     +D  +    HS +D  G  
Sbjct: 1164 CMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSDVNAVTTVHSSSDPFGKT 1223

Query: 1154 DDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQKRLYKRSEAKRSENVDSA 1212
            D+REPL NA++SDSAVIGG+IAVVIFI+ CI  I  R +YQ K+ ++ S+ K  E  ++ 
Sbjct: 1224 DEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHKQSHRTSQMKEKEYPENL 1283

Query: 1213 EAVLKSELNIQNAVNENQKEYF 1234
            ++  ++E+++QN V+E ++EYF
Sbjct: 1284 DSSFRNEIDLQNTVSECKREYF 1305


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 1256 bits (3249), Expect = 0.0
 Identities = 609/890 (68%), Positives = 700/890 (78%), Gaps = 51/890 (5%)

Query: 5   DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64
           DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 30  DCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89

Query: 65  EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124
           EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 90  EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149

Query: 125 IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184
            +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLY  D+K L PI+D+IS
Sbjct: 150 FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVIS 209

Query: 185 LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244
           LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 210 LKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269

Query: 245 QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE-------------------- 284
           QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E                    
Sbjct: 270 QHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSF 329

Query: 285 ----------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 316
                                       GNVSFSC QPQ++PVTFLSSRSYLALP  SGE
Sbjct: 330 HGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGE 389

Query: 317 EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELN 376
           ++VS TFQFRTWN+AG LLF ELQ  SG  +LFL DGKLK +L+Q G+ P ++TAG  LN
Sbjct: 390 DKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLN 449

Query: 377 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436
           DGQWHSVS SAK +H++V VD   A   PL+    I SG TYYFGGC   S GS CKSPL
Sbjct: 450 DGQWHSVSFSAKWSHMNVVVDDDTA-VQPLVAV-LIDSGDTYYFGGCLGNSSGSGCKSPL 507

Query: 437 GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496
           GGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP+YCEHGGECSQSW 
Sbjct: 508 GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 567

Query: 497 TFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTET 556
           TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSGPL PFL+YCNMT++
Sbjct: 568 TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTDS 627

Query: 557 AWTIIQHNGSDLTRVRNTNPENPYAGF-FEYVASMEQLQATINRAEHCEQEFTYYCKKSR 615
           AWT+++H G D   +R     +P +   F Y A   QL+A +N AE CEQ     C  +R
Sbjct: 628 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 687

Query: 616 LVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTN 675
             + +DGTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA +NEWT+
Sbjct: 688 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 747

Query: 676 DTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPT 735
           DT +L+ KEHLPVT+IV+TDTG+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP 
Sbjct: 748 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 807

Query: 736 FHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSP 795
           FHGEL+ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSP
Sbjct: 808 FHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 867

Query: 796 THFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFV 845
           T FNDNQWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+
Sbjct: 868 TPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917



 Score =  336 bits (861), Expect = 9e-92
 Identities = 175/286 (61%), Positives = 219/286 (76%), Gaps = 4/286 (1%)

Query: 926  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 985
            EISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+V
Sbjct: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977

Query: 986  SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1045
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037

Query: 1046 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1105
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097

Query: 1106 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1161
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157

Query: 1162 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
            A + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 64/268 (23%), Positives = 98/268 (36%), Gaps = 38/268 (14%)

Query: 684 EHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSAD 743
           E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393

Query: 744 VSFFFKTTASSGVFLEN---LGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 800
           V+F F+T   +G  L      G   F+ + L+   +    F  G  P  ++  +    ND
Sbjct: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG--LND 450

Query: 801 NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG------ 854
            QWH V         ++ VD  T   QP  A   VL+      + GG      G      
Sbjct: 451 GQWHSVSFSAKWSHMNVVVDDDTA-VQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506

Query: 855 ---FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG-----HCSSYG-------KLCRNG 899
              F GC+R + +    +D          VQ G  G        S G         C +G
Sbjct: 507 LGGFQGCLRLITIGDKAVD-------PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHG 559

Query: 900 GKCRERPIGFFCDCTFSAYTGPFCSNEI 927
           G+C +    F CDC  + YTG  C + +
Sbjct: 560 GECSQSWDTFSCDCLGTGYTGETCHSSL 587



 Score = 38.1 bits (87), Expect = 0.052
 Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 744 VSFFFKTTASSGVFLENLGI-ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTH----- 797
           +S  FK   S+G+ L   G   + I +EL    +V F  + GN     ++   T      
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFF-LNSGNAKLPSTIAPVTLTLGSL 266

Query: 798 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG-------TAT 850
            +D  WH V +E    + +  VD+ T   Q      +  L LN ++  GG        A 
Sbjct: 267 LDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGILSPGRSRAF 324

Query: 851 RQRGFLGCIRSLQLNGMTLDLEERAQ 876
            ++ F GC+ +L  NG  +D+ E A+
Sbjct: 325 TRKSFHGCLENLYYNG--VDVTELAK 348


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
          Length = 1331

 Score = 1217 bits (3148), Expect = 0.0
 Identities = 610/1299 (46%), Positives = 838/1299 (64%), Gaps = 75/1299 (5%)

Query: 6    CDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERME 65
            CD+PLVS LP  +FSSSS +S S+ PG+A++N+R GAGGWSP  S+ YQWLQ+D G R +
Sbjct: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94

Query: 66   VTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSI 125
            ++A+ATQG Y SS+WVT Y +++SD+G NWK Y Q+ +IW F GN N+D VV + LQ  I
Sbjct: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154

Query: 126  KARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISL 185
             AR++R +PL+WN +GRIG+RIEV+GC+Y ++V++ DG   L YRF  K +  +KD+I+L
Sbjct: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214

Query: 186  KFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQ 245
             FKT +S+G++LH EG  GD+ITL+L++A+L L +N G  +L       ++  GSLLDD 
Sbjct: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274

Query: 246  HWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE--------------------- 284
            HWHSV+I+R G+ +N T+D    HF   GEF+ ++LDYE                     
Sbjct: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334

Query: 285  ---------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEE 317
                                       GN+SFSC +P ++PV F ++ SYL +P    ++
Sbjct: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393

Query: 318  EVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKL--KSNLYQPGKLPSDITAGVEL 375
              S +FQFRTWN  GLL+FS      G + + L++ K+    N+ Q      DI++G  L
Sbjct: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453

Query: 376  NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSP 435
            NDGQWH V   AK+N   + +DG  ASA     P Q+ +G  Y+FGG  ++   S     
Sbjct: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513

Query: 436  LGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSW 495
               FQGCM+LI +  ++V+L  V Q   G+F+++ ID C I DRC+PN+CEHGG+CSQ+W
Sbjct: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573

Query: 496  STFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTE 555
             +F C C  TGY GATCHNSIYE SCEAYKH G TS +Y+ID DGSGPL P  +YCNMTE
Sbjct: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633

Query: 556  T-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 614
               WTI+ H+    T V   NPE        Y ASM+Q+ A  + AE+CEQ  +Y+CK S
Sbjct: 634  DKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKMS 693

Query: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674
            RL+N  DG+P +WWVG+ NE   YWGGS P +QKC CG+E NC D +YYCNCDAD  +W 
Sbjct: 694  RLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWR 753

Query: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734
             D G L+YK+HLPV+++V+ DT R  SEA   +GPL CQGDR++WN+ASF   +SYLHF 
Sbjct: 754  KDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFS 813

Query: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794
            TF GE SAD+SF+FKT    GVFLEN+G  DFI++EL+S T V+FSFDVGNGP EI V+S
Sbjct: 814  TFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRS 873

Query: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854
            PT  ND+QWH V  ERN+K+ASLQVD+L  + + AP +GH  L+L SQLFVGG A  Q+G
Sbjct: 874  PTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQG 932

Query: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914
            FLGCIRSL++NG+TLDLEERA+VT     GC GHC+SYG  C NGGKC ER  G+ CDC+
Sbjct: 933  FLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCS 992

Query: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHA------ASFHGDMKLSREM 968
             +AY G FC+ ++ A+F  G  + YNFQ     +++SSS         + H D  L++E 
Sbjct: 993  NTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LAQEE 1050

Query: 969  IKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADG 1028
            I+FSF TT+ P +LL++SSF  ++L+V++   GSLQIRY L   +EP  ++ D +NMA+G
Sbjct: 1051 IRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANG 1110

Query: 1029 QLHHIMINREEGVVFIEIDDNRRRQVHL--SSGTEFSAVKSLVLGRILEHSDVDQDTALA 1086
            Q H + I R E  +F+++D       HL  SS T F++ KSL LG+++E   +DQ+    
Sbjct: 1111 QPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKY 1170

Query: 1087 GAQGFTGCLSAVQLSHVAPLKAALHPSHPDP-VTVTGHVTESSCMAQPGTDATSRERTHS 1145
               GFTGCLS VQ + +APLKAAL  ++    V + G + ES+C A P T +     T  
Sbjct: 1171 NTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDP 1230

Query: 1146 F---------ADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQK 1195
            +         AD        + + N +  +SA+IGG+IAVVIF +LC     +R +++ K
Sbjct: 1231 WHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHK 1290

Query: 1196 RLYKRSEAKRSENVDSAE-AVLKSELNIQNAVNENQKEY 1233
              Y  +EAK +E+ +SA+ A++ ++ N    ++E++KE+
Sbjct: 1291 GTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEW 1329


>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score =  882 bits (2278), Expect = 0.0
 Identities = 459/1238 (37%), Positives = 691/1238 (55%), Gaps = 114/1238 (9%)

Query: 4    YDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGER 63
            Y CD+ LV  L   S  +SS  S    P FARL+   G  GWSP + +   WLQIDL ++
Sbjct: 23   YGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKK 79

Query: 64   MEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQP 123
              + AVATQG + S +WVT Y+L++ D   +W  + Q      F GN N  +VV + L  
Sbjct: 80   HRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHF 139

Query: 124  SIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 183
               AR++R +PL WNP+G+IG+R+ ++GC Y+++++  DG  ++ YRF +     + D+ 
Sbjct: 140  HFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVF 199

Query: 184  SLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLD 243
            +  FKT + DG+LLH EG  GD++TL+L  A L L ++ G + +        ++ G +L+
Sbjct: 200  AFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLN 259

Query: 244  DQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLD--------------------- 282
            DQHWH V + R G+ VNFT+D +   F   G+F  +NLD                     
Sbjct: 260  DQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHN 319

Query: 283  ---------------------------YEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSG 315
                                       +EG V+F C  P   P+ F    +++ +P F  
Sbjct: 320  FRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPR 379

Query: 316  EEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVEL 375
               ++ +F+FRTW+  GLLLFS L    G + L LS+G++  ++ Q G+      AG  L
Sbjct: 380  RGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRL 439

Query: 376  NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSP 435
            NDG WH V+  A++NH  +++D    +   +  P  I +G +Y+FGGCP  +    C S 
Sbjct: 440  NDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSN 499

Query: 436  LGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSW 495
               F GCM L+ + G++V+L  V+   LG ++++  D+CGI+DRC PN CEH G C QSW
Sbjct: 500  QTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSW 559

Query: 496  STFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTE 555
              F C C  TGY+G TCH  +Y++SCEAY+  G TSG + ID DGSGPL+PF++YC++ E
Sbjct: 560  DDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRE 619

Query: 556  T-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEFTYYCKK 613
              AWT+++H+    TRV  ++ E P+ G  +Y  AS E++ A  N ++HCEQ   + C  
Sbjct: 620  NRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYN 679

Query: 614  SRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEW 673
            SRL+N   G P S+W+GR  E   YWGGS P +Q+C CGL+ +C+D   YCNCDAD+ +W
Sbjct: 680  SRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQW 739

Query: 674  TNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHF 733
              D GLL + +HLPVT++VI DT R  SEA + L PL C GDR+ WN+ SF T A+ L F
Sbjct: 740  RTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRF 798

Query: 734  PTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSFDVGNGP 787
            P      S DVSF+F+T+A SGVFLEN+G         ++R+EL +   V F+FDVGNG 
Sbjct: 799  PPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGD 858

Query: 788  FEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVG 846
              ++V S    FND++WH VR E N+K+A L+VD      +P P   ++ ++ +  L+VG
Sbjct: 859  ENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVG 918

Query: 847  GTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERP 906
                ++R F+GC+R+++LNG+TL+LE RA  +    P C GHC+     C +GG+C ER 
Sbjct: 919  SAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERY 978

Query: 907  IGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------------N 944
              + CDC  +A+ GP+C+++I  +F  G+ + YN Q                        
Sbjct: 979  SYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPG 1038

Query: 945  YLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTRTPSLLL 983
            Y+   ++  +   +HG                        ++ E + FSF T+  P++LL
Sbjct: 1039 YIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLL 1098

Query: 984  FVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVF 1043
            +VSSF ++Y++V+I  +G+LQ+RY+L     P V     + + DGQ H I I R    +F
Sbjct: 1099 YVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLF 1156

Query: 1044 IEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1101
            I++D      ++  L   ++  + K+L LGR++E   +D +       GF+GCLS V+ +
Sbjct: 1157 IQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFN 1216

Query: 1102 HVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1133
            +VAPLK       P      + + V G ++ES+C A P
Sbjct: 1217 NVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 944

 Score =  740 bits (1911), Expect = 0.0
 Identities = 353/468 (75%), Positives = 400/468 (85%), Gaps = 1/468 (0%)

Query: 622  GTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLA 681
            GTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA RNEWT+DT +L+
Sbjct: 428  GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487

Query: 682  YKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELS 741
             KEHLPVT+IV+TD G+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+
Sbjct: 488  QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547

Query: 742  ADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDN 801
            ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSPT FNDN
Sbjct: 548  ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607

Query: 802  QWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRS 861
            QWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRS
Sbjct: 608  QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667

Query: 862  LQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGP 921
            LQLNG+ LDLEERA V P V+PGC GHCS+YG LCRNGG+CRE+  G  CDC FSAY GP
Sbjct: 668  LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727

Query: 922  FCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSL 981
            FCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSL
Sbjct: 728  FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787

Query: 982  LLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGV 1041
            LL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE V
Sbjct: 788  LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847

Query: 1042 VFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHS-DVDQDTALAGA 1088
            V +E++ + ++QV LSSGTEF+AVKSL+LG++L  S  VD+   L  A
Sbjct: 848  VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNA 895



 Score =  227 bits (579), Expect = 5e-59
 Identities = 100/133 (75%), Positives = 113/133 (84%)

Query: 423 CPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP 482
           C   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP
Sbjct: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246

Query: 483 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 542
           +YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSG
Sbjct: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306

Query: 543 PLEPFLLYCNMTE 555
           PL PFL+YCNMT+
Sbjct: 307 PLGPFLVYCNMTD 319



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 39/58 (67%), Positives = 49/58 (84%)

Query: 1150 SGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
            SG +D+ EPL NA + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 883  SGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 91/374 (24%), Positives = 138/374 (36%), Gaps = 77/374 (20%)

Query: 271 HARGEFNLMNLDYEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNK 330
           H+  ++ L  L   G+ SF  S       +F +  SYL  P F GE      F F+T   
Sbjct: 506 HSEADYTLGPLLCRGDKSFWNS------ASFNTETSYLHFPAFHGELTADVCFFFKTTVS 559

Query: 331 AGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDIT--AGVELNDGQWHSVSLSAK 388
           +G+  F E   I+  I + L      +  +  G  P ++T  +    ND QWH V     
Sbjct: 560 SGV--FMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERN 617

Query: 389 KNHLSVAVDG--QMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLI 446
               S+ VD   Q    AP  G  ++      + GG   +           GF GC+R +
Sbjct: 618 VKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ---------RGFLGCIRSL 668

Query: 447 SISGKVVDLIS-------VQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFH 499
            ++G  +DL         V+ G  G+ S               + C +GG C +      
Sbjct: 669 QLNGVALDLEERATVMPGVEPGCAGHCSTYG------------HLCRNGGRCREKRRGVT 716

Query: 500 CNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGF----YYIDSDGSGPL----------- 544
           C+C  + Y G  C N I      AY   G++  +    +Y  S+ S  L           
Sbjct: 717 CDCAFSAYDGPFCSNEI-----SAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLT 771

Query: 545 -------------EPFLLYCN--MTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEY--V 587
                           LLY +    E    I+ +NGS   R +    +NP A  F++  +
Sbjct: 772 REMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNM 831

Query: 588 ASMEQLQATINRAE 601
           A  +  Q  INR E
Sbjct: 832 ADGQLHQVKINREE 845



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 18/76 (23%)

Query: 852 QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 911
           Q+G LG  R LQ++           +T    P       SY   C +GG+C +    F C
Sbjct: 223 QQGALGSFRDLQIDS--------CGITDRCLP-------SY---CEHGGECSQSWDTFSC 264

Query: 912 DCTFSAYTGPFCSNEI 927
           DC  + YTG  C + +
Sbjct: 265 DCLGTGYTGETCHSSL 280


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  448 bits (1152), Expect = e-125
 Identities = 212/280 (75%), Positives = 246/280 (87%)

Query: 5   DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64
           DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 30  DCDAPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89

Query: 65  EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124
           EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 90  EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149

Query: 125 IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184
            +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLY  D+K L PI+D+IS
Sbjct: 150 FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVIS 209

Query: 185 LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244
           LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 210 LKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269

Query: 245 QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE 284
           QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E
Sbjct: 270 QHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFE 309



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 744 VSFFFKTTASSGVFLENLGI-ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTH----- 797
           +S  FK   S+G+ L   G   + I +EL    +V F  + GN     ++   T      
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFF-LNSGNAKLPSTIAPVTLTLGSL 266

Query: 798 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTAT------- 850
            +D  WH V +E    + +  VD+ T   Q      +  L LN ++  GG  T       
Sbjct: 267 LDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGIPTPGRSRAF 324

Query: 851 RQRGFLGCIRSLQLNGMTLDLEERAQ 876
            ++ F GC+ +L  NG  +D+ E A+
Sbjct: 325 TRKSFHGCLENLYYNG--VDVTELAK 348



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 17/139 (12%)

Query: 322 TFQFRTWNKAGLLLFSE--------LQLISGGILLFLSDG--KLKSNLYQPGKLPSDITA 371
           + +F+     G+LL  E        L+LI   ++ FL+ G  KL S +      P  +T 
Sbjct: 209 SLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTI-----APVTLTL 263

Query: 372 GVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSK 431
           G  L+D  WHSV +      ++  VD              +       FGG P    G  
Sbjct: 264 GSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTP--GRS 321

Query: 432 CKSPLGGFQGCMRLISISG 450
                  F GC+  +  +G
Sbjct: 322 RAFTRKSFHGCLENLYYNG 340


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  336 bits (861), Expect = 9e-92
 Identities = 176/286 (61%), Positives = 218/286 (76%), Gaps = 4/286 (1%)

Query: 926  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 985
            +ISAYF +GSS+ Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSLLL+V
Sbjct: 2    KISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 61

Query: 986  SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1045
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 62   SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 121

Query: 1046 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1105
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 122  VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAAP 181

Query: 1106 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1161
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 182  LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 241

Query: 1162 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207
            A + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 242  ADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 287


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score =  193 bits (490), Expect = 1e-48
 Identities = 93/136 (68%), Positives = 116/136 (85%)

Query: 939  YNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA 998
            Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSLLL+VSSFY+EYLSVI+A
Sbjct: 3    YHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILA 62

Query: 999  KNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSS 1058
             NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSS
Sbjct: 63   NNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSS 122

Query: 1059 GTEFSAVKSLVLGRIL 1074
            GTEF+AVKSL+LG++L
Sbjct: 123  GTEFNAVKSLILGKVL 138


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  119 bits (299), Expect = 1e-26
 Identities = 142/577 (24%), Positives = 233/577 (40%), Gaps = 92/577 (15%)

Query: 723  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 781
            +F T++SYL   T     S  + F FKTT+  G  L N G   DFI +EL     + + F
Sbjct: 501  TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKG-YIHYVF 559

Query: 782  DVGNGPFEISVQSPTHFNDNQWHHVRVER-NMKEASLQVDQLTPKTQPAPADGHVLLQLN 840
            D+GNGP  I   S    NDNQWH+V + R N    SL+VD    K      +G   L L 
Sbjct: 560  DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD---TKVVTQVINGAKNLDLK 616

Query: 841  SQLFVGGTA-----------TRQRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 888
              L++ G A             + GF GC+ S+ LNG   DL  +    + +++ GC G 
Sbjct: 617  GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGP 676

Query: 889  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FG-SGSSVIYNFQENY 945
             ++  +  C N G C ++  GF CDC+ ++Y+G  C++  + Y FG SG  ++Y +  N 
Sbjct: 677  STTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPAND 736

Query: 946  LLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQI 1005
              S  S   A  F   +K          R    P L  F+    ++    ++   G++ I
Sbjct: 737  RPSTRSDRLAVGFSTTVKDG-----ILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 791

Query: 1006 RYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDD----------------N 1049
              K    +E   VN       DG+ H +   R  G   +++D+                N
Sbjct: 792  SIK----EERTPVN-------DGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFN 840

Query: 1050 RRRQVHLS------------SGTEFSAVKSLVLGRILEHS---DVDQDTALAGAQGFTGC 1094
             + Q+ +             SG  +  +K  VL    E++    ++    L G       
Sbjct: 841  TQAQIAIGGKDKGRLFQGQLSGLYYDGLK--VLNMAAENNPNIKINGSVRLVGE--VPSI 896

Query: 1095 LSAVQLSHVAP-LKAALHPSHPDPVTVTGHVTESSCMAQPGTD--ATSRERTHSFAD--- 1148
            L   Q + + P +   +  +     T T     S+   QP +D   +S E +    D   
Sbjct: 897  LGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVE 956

Query: 1149 -HSGTIDDREP-------LANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKR---- 1196
                T +  EP        +  I+  S+  G ++ +V    LCI  +   +Y+ +     
Sbjct: 957  CEPSTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEG 1016

Query: 1197 LYKRSEAKR--SENVDSAEAVLKSELNIQNAVNENQK 1231
             Y+  E +   S +  S   ++K +     + ++ QK
Sbjct: 1017 SYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQK 1053



 Score =  101 bits (252), Expect = 4e-21
 Identities = 100/426 (23%), Positives = 173/426 (40%), Gaps = 80/426 (18%)

Query: 152 CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 210
           C   + ++  DG   +         +  +D+ S +F + ++ G+L+      + D + L+
Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364

Query: 211 LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 268
           L   R+ L++N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+   
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424

Query: 269 HF-----HARGEFNLM---------------------------------------NLDY- 283
                  H R EF+ +                                       ++DY 
Sbjct: 425 EGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYC 484

Query: 284 EGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE----- 338
           E    F      + PVTF +  SYL+L        +   FQF+T +  G +LF+      
Sbjct: 485 ELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGND 544

Query: 339 ---LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSVSLSA-KKN 390
              ++L+ G I      G     +K N  +P            LND QWH+V ++    N
Sbjct: 545 FIAVELVKGYIHYVFDLGNGPNVIKGNSDRP------------LNDNQWHNVVITRDNSN 592

Query: 391 HLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRLISI 448
             S+ VD ++ +   + G + +   G  Y  G     + +  K  +   GFQGC+  + +
Sbjct: 593 THSLKVDTKVVTQV-INGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDL 651

Query: 449 SGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYR 508
           +G++ DLI+    +L     ++    G S  C  + C + G C Q W  F C+C+ T Y 
Sbjct: 652 NGRLPDLIN---DALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYS 708

Query: 509 GATCHN 514
           G  C++
Sbjct: 709 GNQCND 714



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 63/249 (25%), Positives = 112/249 (44%), Gaps = 43/249 (17%)

Query: 723 SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGI--------------ADFIR 768
           +F+T  +Y+  P ++ +    +SF F+TT  +G+ L   G                DF  
Sbjct: 77  NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136

Query: 769 IELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVD-QLTPKTQ 827
           +EL    +     D+G+G  ++   +    ND +W+HV ++R+ +  ++ V+ + TP T 
Sbjct: 137 VELLDGNLYLL-LDMGSGTIKVKA-TQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTA 194

Query: 828 PAPADGHVLLQLNSQLFVGG---------------TATRQRGFLGCIRSLQLNGMTLDLE 872
              ++   +L L   +++GG               TA    G++GCIR L ++G + ++ 
Sbjct: 195 SGESE---ILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIR 251

Query: 873 ERAQV--TPEVQPGCRG----HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNE 926
           + A++     V+  C       C SY   C+N   C++    F CDCT + Y G  C  E
Sbjct: 252 QLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309

Query: 927 ISAYFGSGS 935
            S     GS
Sbjct: 310 ASILSYDGS 318



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 61/257 (23%), Positives = 108/257 (42%), Gaps = 40/257 (15%)

Query: 285 GNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE----- 338
           G V F C    ++ P+ F +  +Y++LP ++ +   S +F FRT    GL+LF+      
Sbjct: 61  GEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQE 120

Query: 339 ----------------LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHS 382
                           ++L+ G + L L  G     +    K         + NDG+W+ 
Sbjct: 121 RKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQK---------KANDGEWYH 171

Query: 383 VSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLG----- 437
           V +       +++V+ +          E +   G  Y GG P+   G    + L      
Sbjct: 172 VDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLN 231

Query: 438 -GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNY-CEHGGECSQSW 495
            G+ GC+R + I G+  ++   Q   + N + ++     +S +   +Y C++   C   W
Sbjct: 232 YGYVGCIRDLFIDGRSKNIR--QLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGW 289

Query: 496 STFHCNCTNTGYRGATC 512
           + F C+CT TGY G TC
Sbjct: 290 NRFICDCTGTGYWGRTC 306



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 90/393 (22%), Positives = 151/393 (38%), Gaps = 83/393 (21%)

Query: 743  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 792
            DVSF F +  + G+ +       AD +R+EL    V        +  + +   GP   ++
Sbjct: 335  DVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPE--TL 392

Query: 793  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 852
             +    NDN+WH VRV R  K   L VD      +      H  L+ ++     G  T +
Sbjct: 393  YAGQKLNDNEWHTVRVVRRGKSLKLTVDD--DVAEGTMVGDHTRLEFHN--IETGIMTEK 448

Query: 853  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 905
            R        F+G ++SL  NG+                        Y  LC+NG      
Sbjct: 449  RYISVVPSSFIGHLQSLMFNGLL-----------------------YIDLCKNGDI---- 481

Query: 906  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 965
                            +C  E+ A FG     + N   + +  K  SS+ +        S
Sbjct: 482  ---------------DYC--ELKARFG-----LRNIIADPVTFKTKSSYLSLATLQAYTS 519

Query: 966  REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFK 1023
              +  F F+TT     +LF S    ++++V + K     I Y  +    P+V+  N D +
Sbjct: 520  MHLF-FQFKTTSPDGFILFNSGDGNDFIAVELVKG---YIHYVFDLGNGPNVIKGNSD-R 574

Query: 1024 NMADGQLHHIMINREEGVVF-IEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQD 1082
             + D Q H+++I R+      +++D     QV ++          L +  + +    +  
Sbjct: 575  PLNDNQWHNVVITRDNSNTHSLKVDTKVVTQV-INGAKNLDLKGDLYMAGLAQGMYSNLP 633

Query: 1083 TALAGAQGFTGCLSAVQLSHVAP--LKAALHPS 1113
              +A   GF GCL++V L+   P  +  ALH S
Sbjct: 634  KLVASRDGFQGCLASVDLNGRLPDLINDALHRS 666



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 23/115 (20%)

Query: 183 ISLKFKTMQSDGILLHREGP-------------NGDHITLQLRRARLFLLIN--SGEAKL 227
           IS  F+T + +G++L   G                D   ++L    L+LL++  SG  K+
Sbjct: 98  ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 157

Query: 228 PSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLD 282
            +T    N        D  W+ V IQR G+    +V+  R  F A GE  +++L+
Sbjct: 158 KATQKKAN--------DGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLE 204



 Score = 34.3 bits (77), Expect = 0.75
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 21/119 (17%)

Query: 140 KGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISL----KFKTMQSDGI 195
           K R G+R  +      ++ V    KSS L      SL+ ++   S+    +FKT   DG 
Sbjct: 487 KARFGLRNII------ADPVTFKTKSSYL------SLATLQAYTSMHLFFQFKTTSPDGF 534

Query: 196 LLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQR 254
           +L   G   D I ++L +  +  + + G         ++       L+D  WH+V+I R
Sbjct: 535 ILFNSGDGNDFIAVELVKGYIHYVFDLGNG-----PNVIKGNSDRPLNDNQWHNVVITR 588


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  116 bits (291), Expect = 1e-25
 Identities = 99/343 (28%), Positives = 159/343 (46%), Gaps = 39/343 (11%)

Query: 723  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 781
            +F + +SYL   T     S  + F FKTTA  G+ L N G   DFI IEL     + + F
Sbjct: 921  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG-YIHYVF 979

Query: 782  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEA-SLQVDQLTPKTQPAPADGHVLLQLN 840
            D+GNGP  +   S    NDNQWH+V V R+     +L++D    +T    ++G   L L 
Sbjct: 980  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDLK 1036

Query: 841  SQLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 888
             +L++GG +             + GF GC+ S+ LNG   DL  +      +V+ GC G 
Sbjct: 1037 GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGP 1096

Query: 889  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FGSGSSVIYNFQENYL 946
             ++  +  C N G C ++  GF CDCT ++Y GP C++  + Y FG G ++I      Y 
Sbjct: 1097 STTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYT 1151

Query: 947  LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIR 1006
               N            ++ R  + FS        + +  +S   +YL + I   G++ + 
Sbjct: 1152 WPPND-------RPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVI 1203

Query: 1007 YKLNKYQEPDVVNFDFKN--MADGQLHHIMINREEGVVFIEID 1047
            + +      D +  D  N  ++DG+ H +   R  G   +++D
Sbjct: 1204 FNVG----TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242



 Score =  105 bits (262), Expect = 3e-22
 Identities = 105/430 (24%), Positives = 163/430 (37%), Gaps = 88/430 (20%)

Query: 152  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 210
            C   + V+  DG   +         +  +D+ SL+F + ++ G+++      + D + L+
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 211  LRRARLFLLIN-------SGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQV---- 259
            L   ++ L +N          +K P T     L  G  L+D  WH+V + R GK +    
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSKGPET-----LFAGHKLNDNEWHTVRVVRRGKSLQLSV 839

Query: 260  -NFTVDEHRHHFHARGEFN-----------------------LMNLDYEG---------- 285
             N TV+      H R EF+                       L  L + G          
Sbjct: 840  DNVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDG 899

Query: 286  -------NVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE 338
                   N  F      + PVTF S  SYLAL        +   FQF+T    GLLLF+ 
Sbjct: 900  DITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS 959

Query: 339  --------LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSVSLS 386
                    ++L+ G I      G     +K N  +P            +ND QWH+V +S
Sbjct: 960  GNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKP------------VNDNQWHNVVVS 1007

Query: 387  AKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMR 444
                ++               G   +   G  Y GG     F +  K  +   GFQGC+ 
Sbjct: 1008 RDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLA 1067

Query: 445  LISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTN 504
             + ++G++ DLI+    +L     ++    G S  C    C + G C Q W  F C+CT 
Sbjct: 1068 SVDLNGRLPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTM 1124

Query: 505  TGYRGATCHN 514
            T Y G  C++
Sbjct: 1125 TSYGGPVCND 1134



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 69/254 (27%), Positives = 110/254 (43%), Gaps = 31/254 (12%)

Query: 284 EGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLI 342
           +G++SF C    ++ PVTF S  +++ALP +S +   S +  FRT    GLLLFS+ +  
Sbjct: 479 QGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRA 538

Query: 343 SGG------------ILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKN 390
            GG              + L DG L   L           +  ++NDG+W  V       
Sbjct: 539 GGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGR 598

Query: 391 HLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL----------GGFQ 440
             S++V+ +          E +      Y GG P+   G +   PL           G+ 
Sbjct: 599 KGSISVNSRSTPFLATGDSEILDLESELYLGGLPE---GGRVDLPLPPEVWTAALRAGYV 655

Query: 441 GCMRLISISGKVVDL--ISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTF 498
           GC+R + I G+  DL  ++  QG++G       ++     +C    C +GG C + W+ F
Sbjct: 656 GCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETL---KQCASAPCRNGGVCREGWNRF 712

Query: 499 HCNCTNTGYRGATC 512
            C+C  TG+ G  C
Sbjct: 713 ICDCIGTGFLGRVC 726



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 73/267 (27%), Positives = 119/267 (44%), Gaps = 51/267 (19%)

Query: 713 QGDRSF-------WNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGI-- 763
           QGD SF        +  +F++  +++  P +  + +  +S  F+TT  +G+ L + G   
Sbjct: 479 QGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRA 538

Query: 764 ------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERN 811
                       AD+  +EL    +     D+G+G  ++   S    ND +W HV  +R+
Sbjct: 539 GGGAGSHSSAQRADYFAMELLDGHLYLL-LDMGSGGIKLRASS-RKVNDGEWCHVDFQRD 596

Query: 812 MKEASLQVDQLTPKTQPAPADGHV-LLQLNSQLFVGG----------------TATRQRG 854
            ++ S+ V+    ++ P  A G   +L L S+L++GG                TA  + G
Sbjct: 597 GRKGSISVNS---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAG 653

Query: 855 FLGCIRSLQLNGMTLDLE--ERAQVTPEVQPGCRGH----CSSYGKLCRNGGKCRERPIG 908
           ++GC+R L ++G + DL     AQ    V P C       C+S    CRNGG CRE    
Sbjct: 654 YVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNR 711

Query: 909 FFCDCTFSAYTGPFCSNEISAYFGSGS 935
           F CDC  + + G  C  E +     GS
Sbjct: 712 FICDCIGTGFLGRVCEREATVLSYDGS 738



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 97/388 (25%), Positives = 157/388 (40%), Gaps = 77/388 (19%)

Query: 743  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV-VTFSFD---VGNGPFE--ISVQS 794
            DVS  F +  + G+ +       AD +R+EL    + +T + D   VG  P +   ++ +
Sbjct: 755  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFA 814

Query: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR- 853
                NDN+WH VRV R  K   L VD +T + Q A A  H+ L+ ++     G  T +R 
Sbjct: 815  GHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTERRF 870

Query: 854  ------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPI 907
                   F+G +  L  NG               QP        Y   C++G        
Sbjct: 871  ISVVPSNFIGHLSGLVFNG---------------QP--------YMDQCKDG-------- 899

Query: 908  GFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSRE 967
                D T+      F    I A       V +  + +YL      ++A S H        
Sbjct: 900  ----DITYCELNARFGLRAIVA-----DPVTFKSRSSYLALATLQAYA-SMH-------- 941

Query: 968  MIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFKNM 1025
             + F F+TT    LLLF S    +++ + + K     I Y  +    P ++  N D K +
Sbjct: 942  -LFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSD-KPV 996

Query: 1026 ADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTAL 1085
             D Q H+++++R+ G V     D+R    H +          L +G + ++   +    +
Sbjct: 997  NDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLV 1056

Query: 1086 AGAQGFTGCLSAVQLSHVAP--LKAALH 1111
            A   GF GCL++V L+   P  +  ALH
Sbjct: 1057 ASRDGFQGCLASVDLNGRLPDLIADALH 1084



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 26/154 (16%)

Query: 743 DVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFNDN 801
           +++  F+T   +G+ L     AD++ + L+S  V     ++G+G FE  V+     FNDN
Sbjct: 313 EITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAV-WLVINLGSGAFEALVEPVNGKFNDN 371

Query: 802 QWHHVRVERNMKE---------------ASLQVDQLTPKTQPAPADGHVLLQLNSQLFVG 846
            WH VRV RN+++                ++ VD +   T     D + +L  +   ++G
Sbjct: 372 AWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQED-YTMLGSDDFFYIG 430

Query: 847 GTATR--------QRGFLGCIRSLQLNGMTLDLE 872
           G+              F+GC++ +        LE
Sbjct: 431 GSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLE 464



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 54/208 (25%), Positives = 86/208 (41%), Gaps = 35/208 (16%)

Query: 741 SADVSFFFKTTASSGV--FLENLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSPTH 797
           S ++SF  +T A+  +  +L++ G  DF+ + L    + + F+          ++Q  T 
Sbjct: 50  SGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE---PATLQLDTP 106

Query: 798 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG---------- 847
             D++WH V + R+ +  +L VD      +         +Q+ S LFVGG          
Sbjct: 107 VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRRE--MQVASDLFVGGIPPDVRLSAL 164

Query: 848 ---TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGH-----CSSYGKLCRNG 899
              T   +  F G + +L+L        ER       Q G RG      C+     C NG
Sbjct: 165 TLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPARNPCANG 216

Query: 900 GKCRERPIGFF-CDCTFSAYTGPFCSNE 926
           G C     G   CDC+ + + G FCS E
Sbjct: 217 GLCTVLAPGEVGCDCSHTGFGGKFCSEE 244



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 25/232 (10%)

Query: 322 TFQFRTWNKAGLLLFSELQLISGG----ILLFLSDGKLKSNLYQPGKLPSDITAGVELND 377
           +F  RT     LLL+    L  GG    + L L DG+L+         P+ +     + D
Sbjct: 54  SFSLRTNATRALLLY----LDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVAD 109

Query: 378 GQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGC-PDKSFGSKCKSPL 436
            +WH V L+      ++AVDG+  +A       ++      + GG  PD    +   S +
Sbjct: 110 DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTV 169

Query: 437 ---GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP--NYCEHGGEC 491
                F+G +  + +  +   L+   QG  G  +D           C P  N C +GG C
Sbjct: 170 KYEPPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLC 219

Query: 492 S-QSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 542
           +  +     C+C++TG+ G  C    +     A+    +  G       G+G
Sbjct: 220 TVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 158 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 217
           V    G     Y      +    D I+L F+T+Q +G++LH  G + D++ L L+   ++
Sbjct: 289 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 347

Query: 218 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQR 254
           L+IN G     +    VN       +D  WH V + R
Sbjct: 348 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTR 380



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 23/117 (19%)

Query: 183 ISLKFKTMQSDGILL-------------HREGPNGDHITLQLRRARLFLLIN--SGEAKL 227
           ISL F+T + +G+LL             H      D+  ++L    L+LL++  SG  KL
Sbjct: 517 ISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKL 576

Query: 228 PSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE 284
            ++S  VN        D  W  V  QR G++ + +V+     F A G+  +++L+ E
Sbjct: 577 RASSRKVN--------DGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESE 625


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  116 bits (291), Expect = 1e-25
 Identities = 99/343 (28%), Positives = 159/343 (46%), Gaps = 39/343 (11%)

Query: 723  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 781
            +F + +SYL   T     S  + F FKTTA  G+ L N G   DFI IEL     + + F
Sbjct: 881  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG-YIHYVF 939

Query: 782  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEA-SLQVDQLTPKTQPAPADGHVLLQLN 840
            D+GNGP  +   S    NDNQWH+V V R+     +L++D    +T    ++G   L L 
Sbjct: 940  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDLK 996

Query: 841  SQLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 888
             +L++GG +             + GF GC+ S+ LNG   DL  +      +V+ GC G 
Sbjct: 997  GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGP 1056

Query: 889  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FGSGSSVIYNFQENYL 946
             ++  +  C N G C ++  GF CDCT ++Y GP C++  + Y FG G ++I      Y 
Sbjct: 1057 STTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYT 1111

Query: 947  LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIR 1006
               N            ++ R  + FS        + +  +S   +YL + I   G++ + 
Sbjct: 1112 WPPND-------RPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVI 1163

Query: 1007 YKLNKYQEPDVVNFDFKN--MADGQLHHIMINREEGVVFIEID 1047
            + +      D +  D  N  ++DG+ H +   R  G   +++D
Sbjct: 1164 FNVG----TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202



 Score =  109 bits (272), Expect = 2e-23
 Identities = 105/423 (24%), Positives = 163/423 (38%), Gaps = 83/423 (19%)

Query: 152  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 210
            C   + V+  DG   +         +  +D+ SL+F + ++ G+++      + D + L+
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 211  LRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQV-----NFTVDE 265
            L   ++ L +N G+   P T     L  G  L+D  WH+V + R GK +     N TV+ 
Sbjct: 754  LDGGQMKLTVNLGKG--PET-----LFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 266  HRHHFHARGEFN-----------------------LMNLDYEG----------------- 285
                 H R EF+                       L  L + G                 
Sbjct: 807  QMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCEL 866

Query: 286  NVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE------- 338
            N  F      + PVTF S  SYLAL        +   FQF+T    GLLLF+        
Sbjct: 867  NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFI 926

Query: 339  -LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLS 393
             ++L+ G I      G     +K N  +P            +ND QWH+V +S    ++ 
Sbjct: 927  VIELVKGYIHYVFDLGNGPSLMKGNSDKP------------VNDNQWHNVVVSRDPGNVH 974

Query: 394  VAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRLISISGK 451
                          G   +   G  Y GG     F +  K  +   GFQGC+  + ++G+
Sbjct: 975  TLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGR 1034

Query: 452  VVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGAT 511
            + DLI+    +L     ++    G S  C    C + G C Q W  F C+CT T Y G  
Sbjct: 1035 LPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPV 1091

Query: 512  CHN 514
            C++
Sbjct: 1092 CND 1094



 Score =  103 bits (258), Expect = 8e-22
 Identities = 180/819 (21%), Positives = 310/819 (37%), Gaps = 163/819 (19%)

Query: 322  TFQFRTWNKAGLLLFSELQLISGG----ILLFLSDGKLKSNLYQPGKLPSDITAGVELND 377
            +F  RT     LLL+    L  GG    + L L DG+L+         P+ +     + D
Sbjct: 54   SFSLRTNATRALLLY----LDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVAD 109

Query: 378  GQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCP-DKSFGSKCKSPL 436
             +WH V L+      ++AVDG+  +A       ++      + GG P D    +   S +
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTV 169

Query: 437  G---GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP--NYCEHGGEC 491
                 F+G +  + +  +   L+   QG  G  +D           C P  N C +GG C
Sbjct: 170  KYEPPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLC 219

Query: 492  SQ-SWSTFHCNCTNTGYRGATC-----------HNSIYEQSCEAYKHRGNTSGFYYIDSD 539
            +  +     C+C++TG+ G  C           H ++  +  E +      + F+  D  
Sbjct: 220  TVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLS 279

Query: 540  GSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPY-------------AGFFEY 586
             +    P     +    A+  +Q NG  L   ++ +  N               +G FE 
Sbjct: 280  HN----PIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFE- 334

Query: 587  VASMEQLQATINRAEHCEQEFTYYCKK------SRLVNKQDGTPLSWWVGRTNETQTYWG 640
             A +E +    N     +   T   ++      + +    DG   +   G T E  T  G
Sbjct: 335  -ALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT--TGYTQEDYTMLG 391

Query: 641  -------GSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVI 693
                   G SP+    T  L G+ + S  +  C  D     ND  L              
Sbjct: 392  SDDFFYIGGSPN----TADLPGSPV-SNNFMGCLKDVVYKNNDFKL-------------- 432

Query: 694  TDTGRLHSEAAYKLGPLLCQGDRSF-------WNSASFDTEASYLHFPTFHGELSADVSF 746
             +  RL  E   K+     QGD SF        +  +F++  +++  P +  + +  +S 
Sbjct: 433  -ELSRLAKEGDPKMK---LQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISL 488

Query: 747  FFKTTASSGVFLENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISV 792
             F+TT  +G+ L + G               AD+  +EL    +     D+G+G  ++  
Sbjct: 489  DFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLL-LDMGSGGIKLRA 547

Query: 793  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHV-LLQLNSQLFVGG---- 847
             S    ND +W HV  +R+ ++ S+ V+    ++ P  A G   +L L S+L++GG    
Sbjct: 548  SS-RKVNDGEWCHVDFQRDGRKGSISVNS---RSTPFLATGDSEILDLESELYLGGLPEG 603

Query: 848  ------------TATRQRGFLGCIRSLQLNGMTLDLE--ERAQVTPEVQPGCRGH----C 889
                        TA  + G++GC+R L ++G + DL     AQ    V P C       C
Sbjct: 604  GRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQC 663

Query: 890  SSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSK 949
            +S    CRNGG CRE    F CDC  + + G  C  E +     GS  +     N     
Sbjct: 664  ASAP--CRNGGVCREGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPN----- 716

Query: 950  NSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKL 1009
                        M    E +   F + R   L++  +S  +E    +  +    Q++  +
Sbjct: 717  -----------AMHTEAEDVSLRFMSQRAYGLMMATTS--RESADTLRLELDGGQMKLTV 763

Query: 1010 NKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDD 1048
            N  + P+ + F    + D + H + + R    + + +D+
Sbjct: 764  NLGKGPETL-FAGHKLNDNEWHTVRVVRRGKSLQLSVDN 801



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 69/254 (27%), Positives = 110/254 (43%), Gaps = 31/254 (12%)

Query: 284 EGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLI 342
           +G++SF C    ++ PVTF S  +++ALP +S +   S +  FRT    GLLLFS+ +  
Sbjct: 448 QGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRA 507

Query: 343 SGG------------ILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKN 390
            GG              + L DG L   L           +  ++NDG+W  V       
Sbjct: 508 GGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGR 567

Query: 391 HLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL----------GGFQ 440
             S++V+ +          E +      Y GG P+   G +   PL           G+ 
Sbjct: 568 KGSISVNSRSTPFLATGDSEILDLESELYLGGLPE---GGRVDLPLPPEVWTAALRAGYV 624

Query: 441 GCMRLISISGKVVDL--ISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTF 498
           GC+R + I G+  DL  ++  QG++G       ++     +C    C +GG C + W+ F
Sbjct: 625 GCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETL---KQCASAPCRNGGVCREGWNRF 681

Query: 499 HCNCTNTGYRGATC 512
            C+C  TG+ G  C
Sbjct: 682 ICDCIGTGFLGRVC 695



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 95/382 (24%), Positives = 153/382 (40%), Gaps = 74/382 (19%)

Query: 743  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 800
            DVS  F +  + G+ +       AD +R+EL    +   + ++G GP  +        ND
Sbjct: 724  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQM-KLTVNLGKGPETLFAGHK--LND 780

Query: 801  NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR------- 853
            N+WH VRV R  K   L VD +T + Q A A  H+ L+ ++     G  T +R       
Sbjct: 781  NEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTERRFISVVPS 836

Query: 854  GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDC 913
             F+G +  L  NG               QP        Y   C++G            D 
Sbjct: 837  NFIGHLSGLVFNG---------------QP--------YMDQCKDG------------DI 861

Query: 914  TFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSF 973
            T+      F    I A       V +  + +YL      ++A S H         + F F
Sbjct: 862  TYCELNARFGLRAIVA-----DPVTFKSRSSYLALATLQAYA-SMH---------LFFQF 906

Query: 974  RTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFKNMADGQLH 1031
            +TT    LLLF S    +++ + + K     I Y  +    P ++  N D K + D Q H
Sbjct: 907  KTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSD-KPVNDNQWH 962

Query: 1032 HIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGF 1091
            +++++R+ G V     D+R    H +          L +G + ++   +    +A   GF
Sbjct: 963  NVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGF 1022

Query: 1092 TGCLSAVQLSHVAP--LKAALH 1111
             GCL++V L+   P  +  ALH
Sbjct: 1023 QGCLASVDLNGRLPDLIADALH 1044



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 38/268 (14%)

Query: 741 SADVSFFFKTTASSGV--FLENLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSPTH 797
           S ++SF  +T A+  +  +L++ G  DF+ + L    + + F+          ++Q  T 
Sbjct: 50  SGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE---PATLQLDTP 106

Query: 798 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG---------- 847
             D++WH V + R+ +  +L VD      +         +Q+ S LFVGG          
Sbjct: 107 VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRRE--MQVASDLFVGGIPPDVRLSAL 164

Query: 848 ---TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGH-----CSSYGKLCRNG 899
              T   +  F G + +L+L        ER       Q G RG      C+     C NG
Sbjct: 165 TLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPARNPCANG 216

Query: 900 GKCRERPIGFF-CDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASF 958
           G C     G   CDC+ + + G FCS E     G     + +  +   ++    +    +
Sbjct: 217 GLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCY 276

Query: 959 ---HGDMKLSREMIKFSFRTTRTPSLLL 983
              H  ++ S + I  +FRT +   L+L
Sbjct: 277 DLSHNPIQSSTDEITLAFRTLQRNGLML 304



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 158 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 217
           V    G     Y      +    D I+L F+T+Q +G++LH  G + D++ L L+   ++
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH-TGKSADYVNLSLKSGAVW 323

Query: 218 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQR 254
           L+IN G     +    VN       +D  WH V + R
Sbjct: 324 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTR 356



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 23/117 (19%)

Query: 183 ISLKFKTMQSDGILL-------------HREGPNGDHITLQLRRARLFLLIN--SGEAKL 227
           ISL F+T + +G+LL             H      D+  ++L    L+LL++  SG  KL
Sbjct: 486 ISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKL 545

Query: 228 PSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE 284
            ++S  VN        D  W  V  QR G++ + +V+     F A G+  +++L+ E
Sbjct: 546 RASSRKVN--------DGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESE 594


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  114 bits (286), Expect = 4e-25
 Identities = 95/343 (27%), Positives = 155/343 (45%), Gaps = 39/343 (11%)

Query: 723  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 781
            +F T++SY+   T     S  + F FKTT+  G+ L N G   DFI +EL     + + F
Sbjct: 948  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKG-YLHYVF 1006

Query: 782  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNS 841
            D+GNG   I   S    NDNQWH+V + R+   ++L   ++  K       G   L L S
Sbjct: 1007 DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1064

Query: 842  QLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDLEERAQV-TPEVQPGCRGHC 889
             L++GG A             + GF GC+ S+ LNG   DL   A     +++ GC G  
Sbjct: 1065 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1124

Query: 890  SSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGS--GSSVIYNFQENYL 946
            ++  +  C N G C ++  GF CDC+ ++++GP C++  + Y  S  G  + Y +  N  
Sbjct: 1125 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1184

Query: 947  LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV--SSFYKEYLSVIIAKNGSLQ 1004
             S  +               + +   F T +  ++L+ V  SS   +YL + I +    +
Sbjct: 1185 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQG---K 1226

Query: 1005 IRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEID 1047
            I  K N   +   +      + DG+ H +   R  G   +++D
Sbjct: 1227 IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 1269



 Score =  108 bits (270), Expect = 3e-23
 Identities = 114/455 (25%), Positives = 189/455 (41%), Gaps = 93/455 (20%)

Query: 152  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 210
            C   + V+  DG   +  +      +  +D+ SL+F++ ++ GIL+      + D + L+
Sbjct: 752  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810

Query: 211  LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 268
            L   R+ L +N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+ + 
Sbjct: 811  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870

Query: 269  HF------HARGEFN-----------------------LMNLDYEG-------------- 285
                    H R EF+                       L +L + G              
Sbjct: 871  MTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDY 930

Query: 286  ---NVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE---- 338
               N  F      + PVTF +  SY+AL        +   FQF+T +  GL+L++     
Sbjct: 931  CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990

Query: 339  ----LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHL-S 393
                ++L+ G  L ++ D    +NL +        ++   LND QWH+V +S   ++L +
Sbjct: 991  DFIVVELVKG-YLHYVFDLGNGANLIKG-------SSNKPLNDNQWHNVMISRDTSNLHT 1042

Query: 394  VAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRLISISGK 451
            V +D ++ +     G   +      Y GG   +++ S  K      GFQGC+  + ++G+
Sbjct: 1043 VKIDTKITTQITA-GARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGR 1101

Query: 452  VVDLISVQQGSLGNFSDLQID-SC-GISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRG 509
            + DLIS        F + QI+  C G S  C  + C + G C Q W  F C+C+ T + G
Sbjct: 1102 LPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSG 1156

Query: 510  ATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPL 544
              C                N  G  YI S G G +
Sbjct: 1157 PLC----------------NDPGTTYIFSKGGGQI 1175



 Score = 97.4 bits (241), Expect = 7e-20
 Identities = 90/394 (22%), Positives = 165/394 (41%), Gaps = 69/394 (17%)

Query: 698  RLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVF 757
            ++H   A+K     C+   +  +  +F+T  S++  P ++ + +  +SF F+TT  +G+ 
Sbjct: 504  KIHGVVAFK-----CENVATL-DPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLI 557

Query: 758  LENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 803
            L + G                DF  IE+    +     D+G+G  +I        ND +W
Sbjct: 558  LFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLL-LDMGSGTIKIKALLKK-VNDGEW 615

Query: 804  HHVRVERNMKEASLQVDQL-TPKTQPAPADGHVLLQLNSQLFVGG--------------- 847
            +HV  +R+ +  ++ V+ L TP T P  ++   +L L+ +L++GG               
Sbjct: 616  YHVDFQRDGRSGTISVNTLRTPYTAPGESE---ILDLDDELYLGGLPENKAGLVFPTEVW 672

Query: 848  TATRQRGFLGCIRSLQLNGMTLDLEERAQV--TPEVQPGCRGHCSS--YGKLCRNGGKCR 903
            TA    G++GCIR L ++G + D+ + A+V  T  V+P C    +       C+N G CR
Sbjct: 673  TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCR 732

Query: 904  ERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMK 963
            +    + CDC+ + Y G  C  E +     GS  +                       M 
Sbjct: 733  DGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFM----------------KIQLPVVMH 776

Query: 964  LSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQ-------IRYKLNKYQEPD 1016
               E +   FR+ R   +L+  +S        +    G ++       IR   N  + P+
Sbjct: 777  TEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPE 836

Query: 1017 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNR 1050
             + F   N+ D + H + + R    + + +DD +
Sbjct: 837  TL-FAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQ 869



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 63/262 (24%), Positives = 114/262 (43%), Gaps = 50/262 (19%)

Query: 285 GNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE----- 338
           G V+F C    ++ P+TF +  S+++LP ++ ++  S +F FRT    GL+LFS      
Sbjct: 507 GVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRH 566

Query: 339 ----------------LQLISGGILLFLSDG----KLKSNLYQPGKLPSDITAGVELNDG 378
                           ++++ G + L L  G    K+K+ L +             +NDG
Sbjct: 567 QKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-------------VNDG 613

Query: 379 QWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLG- 437
           +W+ V         +++V+            E +      Y GG P+   G    + +  
Sbjct: 614 EWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWT 673

Query: 438 -----GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCG--ISDRCLPNYCEHGGE 490
                G+ GC+R + I G+  D+   Q   + + + ++  SC    +  CL N C++ G 
Sbjct: 674 ALLNYGYVGCIRDLFIDGQSKDIR--QMAEVQSTAGVK-PSCSKETAKPCLSNPCKNNGM 730

Query: 491 CSQSWSTFHCNCTNTGYRGATC 512
           C   W+ + C+C+ TGY G +C
Sbjct: 731 CRDGWNRYVCDCSGTGYLGRSC 752



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 56/225 (24%), Positives = 93/225 (41%), Gaps = 26/225 (11%)

Query: 727 EASYLHFPTFHGELSADVSFFFKTTASSGVFL--ENLGIADFIRIELRSPTVVTFSFDVG 784
           E  +  FP ++    +++SF  KT ++ G+ L  ++ G  DF+ + L     +  SF + 
Sbjct: 37  EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 785 NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLF 844
                 ++ + T  ND  WH VR+ R  +  +L +DQ+  K     +    +    S LF
Sbjct: 97  CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF-SGLF 154

Query: 845 VGGTATRQRG---------------FLGCIRSLQLNGMTLDLEERAQVTPEVQPG----- 884
           VGG     R                F G IR +++N   +   +  +V  + +P      
Sbjct: 155 VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 885 --CRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEI 927
             C       G +C NGG C        CDC+ + + G  CS EI
Sbjct: 215 SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 91/382 (23%), Positives = 152/382 (39%), Gaps = 78/382 (20%)

Query: 743  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 792
            DVS  F++  + G+ +       AD +R+EL +  V        +  + +   GP  +  
Sbjct: 781  DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF- 839

Query: 793  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 852
             +  + NDN+WH VRV R  K   L VD     T     D H  L+ ++     G  T +
Sbjct: 840  -AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN--IETGIITER 895

Query: 853  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 905
            R        F+G ++SL  NGM                       +Y  LC+NG      
Sbjct: 896  RYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNGDI---- 928

Query: 906  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 965
                            +C  E++A FG       N   + +  K  SS+ A        S
Sbjct: 929  ---------------DYC--ELNARFG-----FRNIIADPVTFKTKSSYVALATLQAYTS 966

Query: 966  REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1025
              +  F F+TT    L+L+ S    +++ V + K G L   + L       +     K +
Sbjct: 967  MHLF-FQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANL-IKGSSNKPL 1023

Query: 1026 ADGQLHHIMINRE-EGVVFIEIDDNRRRQVHLSSGTEFSAVKS-LVLGRILEHSDVDQDT 1083
             D Q H++MI+R+   +  ++ID     Q+  ++G     +KS L +G + + +      
Sbjct: 1024 NDNQWHNVMISRDTSNLHTVKIDTKITTQI--TAGARNLDLKSDLYIGGVAKETYKSLPK 1081

Query: 1084 ALAGAQGFTGCLSAVQLSHVAP 1105
             +   +GF GCL++V L+   P
Sbjct: 1082 LVHAKEGFQGCLASVDLNGRLP 1103



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 51/214 (23%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 318 EVSATFQFRTWNKAGLLLFSELQLISGGILLFLS-DGKLKSNLYQPGKLPSDITAGVELN 376
           E   +FQ +T +  GL+L+ + +     + L L+  G+L+ +       P+ + A   +N
Sbjct: 51  ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 377 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQ---IYSGGTYYFGGCPDKSFGSKCK 433
           DG WHSV +  +  + ++ +D   A    +    +   ++SG   + GG P +   +  K
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALK 168

Query: 434 SPLGG------FQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDS-----CGISDRCLP 482
             L        F+G +R + ++   V  + V  G +    D   +S     C   +    
Sbjct: 169 LTLASVREREPFKGWIRDVRVNSSQV--LPVDSGEV-KLDDEPPNSGGGSPCEAGEEGEG 225

Query: 483 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSI 516
             C +GG CS       C+C+ TG+RG  C   I
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 41/162 (25%), Positives = 76/162 (46%), Gaps = 28/162 (17%)

Query: 741 SADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFN 799
           S +++  FKT   +G+ L     AD++ + L++  V +   ++G+G FE  V+     FN
Sbjct: 338 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAV-SLVINLGSGAFEALVEPVNGKFN 396

Query: 800 DNQWHHVRVERNMKEAS---------------LQVDQLTPKTQPAPADGHVLLQLNSQLF 844
           DN WH V+V RN+++ S               + VD +   T     D + +L  +   +
Sbjct: 397 DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQED-YTMLGSDDFFY 455

Query: 845 VGGTATR--------QRGFLGCIRSL--QLNGMTLDLEERAQ 876
           VGG+ +            F+GC++ +  + N + L+L   A+
Sbjct: 456 VGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 497



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 158 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 217
           +    G     Y   Q  +    D I+L FKT+Q +G++LH  G + D++ L L+   + 
Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 374

Query: 218 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQR 254
           L+IN G     +    VN       +D  WH V + R
Sbjct: 375 LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTR 407



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 19/115 (16%)

Query: 183 ISLKFKTMQSDGILLHREGP-------------NGDHITLQLRRARLFLLINSGEAKLPS 229
           IS  F+T + +G++L   G                D   +++    L+LL++ G   +  
Sbjct: 544 ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKI 603

Query: 230 TSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE 284
            + L  +      +D  W+ V  QR G+    +V+  R  + A GE  +++LD E
Sbjct: 604 KALLKKV------NDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDE 652


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  114 bits (286), Expect = 4e-25
 Identities = 95/343 (27%), Positives = 155/343 (45%), Gaps = 39/343 (11%)

Query: 723  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 781
            +F T++SY+   T     S  + F FKTT+  G+ L N G   DFI +EL     + + F
Sbjct: 908  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKG-YLHYVF 966

Query: 782  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNS 841
            D+GNG   I   S    NDNQWH+V + R+   ++L   ++  K       G   L L S
Sbjct: 967  DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1024

Query: 842  QLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDLEERAQV-TPEVQPGCRGHC 889
             L++GG A             + GF GC+ S+ LNG   DL   A     +++ GC G  
Sbjct: 1025 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1084

Query: 890  SSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGS--GSSVIYNFQENYL 946
            ++  +  C N G C ++  GF CDC+ ++++GP C++  + Y  S  G  + Y +  N  
Sbjct: 1085 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1144

Query: 947  LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV--SSFYKEYLSVIIAKNGSLQ 1004
             S  +               + +   F T +  ++L+ V  SS   +YL + I +    +
Sbjct: 1145 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQG---K 1186

Query: 1005 IRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEID 1047
            I  K N   +   +      + DG+ H +   R  G   +++D
Sbjct: 1187 IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 1229



 Score =  108 bits (270), Expect = 3e-23
 Identities = 114/455 (25%), Positives = 189/455 (41%), Gaps = 93/455 (20%)

Query: 152  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 210
            C   + V+  DG   +  +      +  +D+ SL+F++ ++ GIL+      + D + L+
Sbjct: 712  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770

Query: 211  LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 268
            L   R+ L +N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+ + 
Sbjct: 771  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830

Query: 269  HF------HARGEFN-----------------------LMNLDYEG-------------- 285
                    H R EF+                       L +L + G              
Sbjct: 831  MTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDY 890

Query: 286  ---NVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE---- 338
               N  F      + PVTF +  SY+AL        +   FQF+T +  GL+L++     
Sbjct: 891  CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 950

Query: 339  ----LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHL-S 393
                ++L+ G  L ++ D    +NL +        ++   LND QWH+V +S   ++L +
Sbjct: 951  DFIVVELVKG-YLHYVFDLGNGANLIKG-------SSNKPLNDNQWHNVMISRDTSNLHT 1002

Query: 394  VAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRLISISGK 451
            V +D ++ +     G   +      Y GG   +++ S  K      GFQGC+  + ++G+
Sbjct: 1003 VKIDTKITTQITA-GARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGR 1061

Query: 452  VVDLISVQQGSLGNFSDLQID-SC-GISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRG 509
            + DLIS        F + QI+  C G S  C  + C + G C Q W  F C+C+ T + G
Sbjct: 1062 LPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSG 1116

Query: 510  ATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPL 544
              C                N  G  YI S G G +
Sbjct: 1117 PLC----------------NDPGTTYIFSKGGGQI 1135



 Score = 97.4 bits (241), Expect = 7e-20
 Identities = 90/394 (22%), Positives = 165/394 (41%), Gaps = 69/394 (17%)

Query: 698  RLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVF 757
            ++H   A+K     C+   +  +  +F+T  S++  P ++ + +  +SF F+TT  +G+ 
Sbjct: 464  KIHGVVAFK-----CENVATL-DPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLI 517

Query: 758  LENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 803
            L + G                DF  IE+    +     D+G+G  +I        ND +W
Sbjct: 518  LFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLL-LDMGSGTIKIKALLKK-VNDGEW 575

Query: 804  HHVRVERNMKEASLQVDQL-TPKTQPAPADGHVLLQLNSQLFVGG--------------- 847
            +HV  +R+ +  ++ V+ L TP T P  ++   +L L+ +L++GG               
Sbjct: 576  YHVDFQRDGRSGTISVNTLRTPYTAPGESE---ILDLDDELYLGGLPENKAGLVFPTEVW 632

Query: 848  TATRQRGFLGCIRSLQLNGMTLDLEERAQV--TPEVQPGCRGHCSS--YGKLCRNGGKCR 903
            TA    G++GCIR L ++G + D+ + A+V  T  V+P C    +       C+N G CR
Sbjct: 633  TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCR 692

Query: 904  ERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMK 963
            +    + CDC+ + Y G  C  E +     GS  +                       M 
Sbjct: 693  DGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFM----------------KIQLPVVMH 736

Query: 964  LSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQ-------IRYKLNKYQEPD 1016
               E +   FR+ R   +L+  +S        +    G ++       IR   N  + P+
Sbjct: 737  TEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPE 796

Query: 1017 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNR 1050
             + F   N+ D + H + + R    + + +DD +
Sbjct: 797  TL-FAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQ 829



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 63/262 (24%), Positives = 114/262 (43%), Gaps = 50/262 (19%)

Query: 285 GNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE----- 338
           G V+F C    ++ P+TF +  S+++LP ++ ++  S +F FRT    GL+LFS      
Sbjct: 467 GVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRH 526

Query: 339 ----------------LQLISGGILLFLSDG----KLKSNLYQPGKLPSDITAGVELNDG 378
                           ++++ G + L L  G    K+K+ L +             +NDG
Sbjct: 527 QKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-------------VNDG 573

Query: 379 QWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLG- 437
           +W+ V         +++V+            E +      Y GG P+   G    + +  
Sbjct: 574 EWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWT 633

Query: 438 -----GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCG--ISDRCLPNYCEHGGE 490
                G+ GC+R + I G+  D+   Q   + + + ++  SC    +  CL N C++ G 
Sbjct: 634 ALLNYGYVGCIRDLFIDGQSKDIR--QMAEVQSTAGVK-PSCSKETAKPCLSNPCKNNGM 690

Query: 491 CSQSWSTFHCNCTNTGYRGATC 512
           C   W+ + C+C+ TGY G +C
Sbjct: 691 CRDGWNRYVCDCSGTGYLGRSC 712



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 78/346 (22%), Positives = 141/346 (40%), Gaps = 43/346 (12%)

Query: 727  EASYLHFPTFHGELSADVSFFFKTTASSGVFL--ENLGIADFIRIELRSPTVVTFSFDVG 784
            E  +  FP ++    +++SF  KT ++ G+ L  ++ G  DF+ + L     +  SF + 
Sbjct: 37   EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 785  NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLF 844
                  ++ + T  ND  WH VR+ R  +  +L +DQ+  K     +     + + S LF
Sbjct: 97   CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRD-MTVFSGLF 154

Query: 845  VGG--------------TATRQR-GFLGCIRSLQLNGMTLDLEERAQVTPEVQP------ 883
            VGG               + R+R  F G IR +++N   +   +  +V  + +P      
Sbjct: 155  VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 884  -GCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQ 942
              C       G +C NGG C        CDC+ + + G  CS E +   G    + +   
Sbjct: 215  SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEG----LAHLMM 270

Query: 943  ENYLLSKNSSSHAASFHGD-----------MKLSREMIKFSFRTTRTPSLLLFVSSFYKE 991
             +   SK    + A+F G            ++ S + I  SF+T +   L+L       +
Sbjct: 271  GDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK-SAD 329

Query: 992  YLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINR 1037
            Y+++ + KNG++ +   L       +V        D   H + + R
Sbjct: 330  YVNLAL-KNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTR 374



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 91/382 (23%), Positives = 152/382 (39%), Gaps = 78/382 (20%)

Query: 743  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 792
            DVS  F++  + G+ +       AD +R+EL +  V        +  + +   GP  +  
Sbjct: 741  DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF- 799

Query: 793  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 852
             +  + NDN+WH VRV R  K   L VD     T     D H  L+ ++     G  T +
Sbjct: 800  -AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN--IETGIITER 855

Query: 853  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 905
            R        F+G ++SL  NGM                       +Y  LC+NG      
Sbjct: 856  RYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNGDI---- 888

Query: 906  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 965
                            +C  E++A FG       N   + +  K  SS+ A        S
Sbjct: 889  ---------------DYC--ELNARFG-----FRNIIADPVTFKTKSSYVALATLQAYTS 926

Query: 966  REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1025
              +  F F+TT    L+L+ S    +++ V + K G L   + L       +     K +
Sbjct: 927  MHLF-FQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANL-IKGSSNKPL 983

Query: 1026 ADGQLHHIMINRE-EGVVFIEIDDNRRRQVHLSSGTEFSAVKS-LVLGRILEHSDVDQDT 1083
             D Q H++MI+R+   +  ++ID     Q+  ++G     +KS L +G + + +      
Sbjct: 984  NDNQWHNVMISRDTSNLHTVKIDTKITTQI--TAGARNLDLKSDLYIGGVAKETYKSLPK 1041

Query: 1084 ALAGAQGFTGCLSAVQLSHVAP 1105
             +   +GF GCL++V L+   P
Sbjct: 1042 LVHAKEGFQGCLASVDLNGRLP 1063



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 41/155 (26%), Positives = 76/155 (49%), Gaps = 21/155 (13%)

Query: 741 SADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFN 799
           S +++  FKT   +G+ L     AD++ + L++  V +   ++G+G FE  V+     FN
Sbjct: 305 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAV-SLVINLGSGAFEALVEPVNGKFN 363

Query: 800 DNQWHHVRVERNMKEAS--------LQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATR 851
           DN WH V+V RN+++ S        + VD +   T     D + +L  +   +VGG+ + 
Sbjct: 364 DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYVGGSPST 422

Query: 852 --------QRGFLGCIRSL--QLNGMTLDLEERAQ 876
                      F+GC++ +  + N + L+L   A+
Sbjct: 423 ADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 457



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 50/210 (23%), Positives = 91/210 (43%), Gaps = 20/210 (9%)

Query: 318 EVSATFQFRTWNKAGLLLFSELQLISGGILLFLS-DGKLKSNLYQPGKLPSDITAGVELN 376
           E   +FQ +T +  GL+L+ + +     + L L+  G+L+ +       P+ + A   +N
Sbjct: 51  ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 377 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQ---IYSGGTYYFGGCPDKSFGSKCK 433
           DG WHSV +  +  + ++ +D   A    +    +   ++SG   + GG P +   +  K
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALK 168

Query: 434 SPLGG------FQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDS-----CGISDRCLP 482
             L        F+G +R + ++   V  + V  G +    D   +S     C   +    
Sbjct: 169 LTLASVREREPFKGWIRDVRVNSSQV--LPVDSGEV-KLDDEPPNSGGGSPCEAGEEGEG 225

Query: 483 NYCEHGGECSQSWSTFHCNCTNTGYRGATC 512
             C +GG CS       C+C+ TG+RG  C
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 158 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 217
           +    G     Y   Q  +    D I+L FKT+Q +G++LH  G + D++ L L+   + 
Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLH-TGKSADYVNLALKNGAVS 341

Query: 218 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQR 254
           L+IN G     +    VN       +D  WH V + R
Sbjct: 342 LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTR 374



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 19/115 (16%)

Query: 183 ISLKFKTMQSDGILLHREGP-------------NGDHITLQLRRARLFLLINSGEAKLPS 229
           IS  F+T + +G++L   G                D   +++    L+LL++ G   +  
Sbjct: 504 ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKI 563

Query: 230 TSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE 284
            + L  +      +D  W+ V  QR G+    +V+  R  + A GE  +++LD E
Sbjct: 564 KALLKKV------NDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDE 612


>gi|239752499 PREDICTED: similar to cell recognition molecule Caspr2,
            partial [Homo sapiens]
          Length = 140

 Score =  107 bits (268), Expect = 5e-23
 Identities = 49/74 (66%), Positives = 63/74 (85%)

Query: 1001 GSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGT 1060
            GSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSSGT
Sbjct: 2    GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 61

Query: 1061 EFSAVKSLVLGRIL 1074
            EF+AVKSL+LG++L
Sbjct: 62   EFNAVKSLILGKVL 75


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 49/126 (38%), Positives = 67/126 (53%), Gaps = 6/126 (4%)

Query: 31   PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQG--GYGSSNWVTSYLLMF 88
            P  ARLN +     W    +N  QWL+IDL +  ++TA+ TQG     S  +V SY + +
Sbjct: 2098 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHY 2157

Query: 89   SDSGWNWKQYRQEDSIWG--FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMR 146
            S+ G  WK YR + S+    F GN N    V     P I +RF+R IP  WN    I +R
Sbjct: 2158 SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQS--IALR 2215

Query: 147  IEVFGC 152
            +E+FGC
Sbjct: 2216 LELFGC 2221



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 43/158 (27%), Positives = 75/158 (47%), Gaps = 12/158 (7%)

Query: 5    DCDDP--LVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWS--PLVSN--KYQWLQI 58
            DC  P  L + +   S   +SE      P  ARLN       WS   L +      W+Q+
Sbjct: 1906 DCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQV 1965

Query: 59   DLGERMEVTAVATQGG--YGSSNWVTSYLLMFSDSGWNWKQYRQEDS--IWGFSGNANAD 114
            D+ + + +T + TQG   Y  S + T + + +S +  NW+ ++   +  +  F+GN++A 
Sbjct: 1966 DMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDAS 2025

Query: 115  SVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152
            ++   +  P I AR++R  P       R  +R+E+ GC
Sbjct: 2026 TIKENQFDPPIVARYIRISPT--RAYNRPTLRLELQGC 2061


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 63/230 (27%), Positives = 99/230 (43%), Gaps = 18/230 (7%)

Query: 291  CSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFL 350
            C +    PV     RS+LA P       +    +FR     GLLL++        + L L
Sbjct: 1366 CEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALAL 1425

Query: 351  SDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPE 410
             DG+++   +  G  P+ +T+ V +  GQWH + LS      +++VDG+     P+LG  
Sbjct: 1426 LDGRVQLR-FDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGE----TPVLGES 1480

Query: 411  QIYSGG-----TYYFGGCPDKSFGSKCKSPL--GGFQGCMRLISISGKVVDLISVQQGSL 463
               + G       + GG P+       +      G +GC+RL+ ++ + ++L  +  G+ 
Sbjct: 1481 PSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL-GIGPGAA 1539

Query: 464  GNFSDLQIDSCGISDRCLPNYCEHGGECSQ-SWSTFHCNCTNTGYRGATC 512
               S   +  CG    CLPN C  G  C       FHC C   G  G TC
Sbjct: 1540 TRGSG--VGECG-DHPCLPNPCHGGAPCQNLEAGRFHCQCP-PGRVGPTC 1585



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 72/281 (25%), Positives = 112/281 (39%), Gaps = 33/281 (11%)

Query: 748  FKTTASSGVFLENL----GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 803
            F     SG+ L N     G  DF+ + LR   +  F +D+G G   I  + P       W
Sbjct: 1668 FLARGPSGLLLYNGQKTDGKGDFVSLALRDRRL-EFRYDLGKGAAVIRSREPVTLG--AW 1724

Query: 804  HHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGT---------ATRQRG 854
              V +ERN ++ +L+V    P+        H +L L   L+VGG          A    G
Sbjct: 1725 TRVSLERNGRKGALRVGD-GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSG 1783

Query: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCS-SYGKLCRNGGKCRERPIGFFCDC 913
            F G I+ + L G  L   E      +V       C+ + G  C NG  C  R   + C C
Sbjct: 1784 FDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLC 1843

Query: 914  TFSAYTGPFCSNE-ISAYFGSGSSVIYNFQE--NYLLSKNSSSHAASFHGDMKLSREMIK 970
                ++GP C    +    G   ++ ++ +    YL +   S  A        L     +
Sbjct: 1844 P-GGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKA--------LQSNHFE 1894

Query: 971  FSFRTTRTPSLLLFVSSFYK--EYLSVIIAKNGSLQIRYKL 1009
             S RT  T  L+L+     +  +Y+++ I  +G LQ+ Y L
Sbjct: 1895 LSLRTEATQGLVLWSGKATERADYVALAIV-DGHLQLSYNL 1934



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 13/114 (11%)

Query: 780  SFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQL 839
            S+++G+ P  + ++S    N N+W  V   R  +E SLQV    P T  +P  G   L  
Sbjct: 1931 SYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL-GATQLDT 1987

Query: 840  NSQLFVGG----------TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQP 883
            +  L++GG                GF+GC+R + +    L L E A   PE++P
Sbjct: 1988 DGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRP 2041



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 17/211 (8%)

Query: 317  EEVSATFQFRTWNKAGLLLFSELQLISGG--ILLFLSDGKLKSNLYQPGKLPSDITAGVE 374
            E+++    F     +GLLL++  +    G  + L L D +L+   Y  GK  + I +   
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFR-YDLGKGAAVIRSREP 1718

Query: 375  LNDGQWHSVSL--SAKKNHLSVAVDGQMASAAPLLGPEQIYS-GGTYYFGGCPDKSFGSK 431
            +  G W  VSL  + +K  L V    ++   +P+  P  + +     Y GG PD S  ++
Sbjct: 1719 VTLGAWTRVSLERNGRKGALRVGDGPRVLGESPV--PHTVLNLKEPLYVGGAPDFSKLAR 1776

Query: 432  CKSPLGGFQGCMRLISISGK--VVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGG 489
              +   GF G ++L+S+ G+  +     ++Q  + +F+      C    R   + C +G 
Sbjct: 1777 AAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAG---HPC---TRASGHPCLNGA 1830

Query: 490  ECSQSWSTFHCNCTNTGYRGATCHNSIYEQS 520
             C    + + C C   G+ G  C   + E+S
Sbjct: 1831 SCVPREAAYVCLCPG-GFSGPHCEKGLVEKS 1860


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 51/160 (31%), Positives = 82/160 (51%), Gaps = 15/160 (9%)

Query: 6   CDDPLV---SALPQASFSSSSELSS------SHGPGFARLNRRDGAGGWSPLVSNKYQWL 56
           C +PL    +++P    ++SS   +      S  P +ARL+++     W        QWL
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289

Query: 57  QIDLGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYR--QEDSIWGFSGNAN 112
           Q+DLG   EVT + TQG   +GS  +V SY + +S+   NW +Y+  +  S   F GN +
Sbjct: 290 QVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWD 349

Query: 113 ADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152
             S      +  I AR++R +P+ W+   RI +R+E+ GC
Sbjct: 350 NHSHKKNLFETPILARYVRILPVAWH--NRIALRLELLGC 387



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 17/131 (12%)

Query: 31  PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMF 88
           P  ARLNR      W+P  ++   W+Q++L  RM VT V TQG     S  ++ ++ + +
Sbjct: 103 PELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAY 162

Query: 89  SDSGWNW-------KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKG 141
           S +G  +       K++++      F GN N ++V     +  ++A+++R  P   +   
Sbjct: 163 SLNGHEFDFIHDVNKKHKE------FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT-- 214

Query: 142 RIGMRIEVFGC 152
              +R E+ GC
Sbjct: 215 ACTLRFELLGC 225


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 6   CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 59
           C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117

Query: 60  LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 117
             + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177

Query: 118 YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152
              L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 6    CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 59
            C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 2193 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 2252

Query: 60   LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 117
              + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 2253 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 2312

Query: 118  YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 152
               L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 2313 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 2345



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 8/130 (6%)

Query: 31   PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYG--SSNWVTSYLLMF 88
            P  ARL+       WS      + W+++DL   M +  + TQG     SS +++ +++M+
Sbjct: 2067 PKLARLHYSGSINAWS--TKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMY 2124

Query: 89   SDSGWNWKQYRQEDS--IWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMR 146
            S  G  W+ YR   +  +  F GN ++  + +    P I AR++R  P  ++   R  +R
Sbjct: 2125 SLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSI--RSTLR 2182

Query: 147  IEVFGCAYRS 156
            +E+ GC   S
Sbjct: 2183 MELMGCDLNS 2192


>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
          Length = 4588

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 29/183 (15%)

Query: 779  FSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQ 838
            + FD G+GP  +SVQS    ND QWH V +E N   A L +DQ+   +  AP      L 
Sbjct: 3888 YKFDCGSGPGIVSVQS-IQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKT-LN 3945

Query: 839  LNSQLFVGGTATRQ-----------RGFLGCIRSLQLNGMTLDLEER------AQVTPEV 881
            L++ +F GG   +Q            GF GC+ S+ LNG  L L  +       + + +V
Sbjct: 3946 LDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDV 4005

Query: 882  QPGC----RGHCSSYGKLCRNGGKCRERPI-GFFCDCTFSAYTGPFCSNEISAYFGSGSS 936
             PGC       C+S    C+NGG C   P  G++C C+ + Y G  C  EIS    S   
Sbjct: 4006 SPGCFLTATEDCAS--NPCQNGGVCNPSPAGGYYCKCS-ALYIGTHC--EISVNPCSSKP 4060

Query: 937  VIY 939
             +Y
Sbjct: 4061 CLY 4063



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 57/234 (24%), Positives = 110/234 (47%), Gaps = 14/234 (5%)

Query: 291  CSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFL 350
            C    SM +T  S   Y  L +   + E+  T + RT++   +++++     S   +L +
Sbjct: 3826 CPGSSSMTLTGNSYVKY-RLTENENKLEMKLTMRLRTYSTHAVVMYARGTDYS---ILEI 3881

Query: 351  SDGKLKSNLYQPGKLPSDITA-GVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGP 409
              G+L+   +  G  P  ++   +++NDGQWH+V+L    N+  + +D    ++    G 
Sbjct: 3882 HHGRLQYK-FDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGT 3940

Query: 410  EQIYSGGTYYFGGCPDKSFGSK-CKSPL--GGFQGCMRLISISGKVVDLISVQQGSLGNF 466
             +  +   Y F G   +  G++  +SP    GF+GCM  I ++G+ + L S  +      
Sbjct: 3941 LKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIE 4000

Query: 467  SDLQID-SCGI--SDRCLPNYCEHGGECSQS-WSTFHCNCTNTGYRGATCHNSI 516
              + +   C +  ++ C  N C++GG C+ S    ++C C+   Y G  C  S+
Sbjct: 4001 ESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSAL-YIGTHCEISV 4053



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 78/380 (20%), Positives = 147/380 (38%), Gaps = 43/380 (11%)

Query: 150  FGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITL 209
            FG    S  + L G S + YR  +   + ++  ++++ +T  +  ++++  G   D+  L
Sbjct: 3823 FGQCPGSSSMTLTGNSYVKYRLTENE-NKLEMKLTMRLRTYSTHAVVMYARGT--DYSIL 3879

Query: 210  QLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDE-HRH 268
            ++   RL    + G    P   ++ ++ +    +D  WH+V ++  G      +D+ H  
Sbjct: 3880 EIHHGRLQYKFDCGSG--PGIVSVQSIQV----NDGQWHAVALEVNGNYARLVLDQVHTA 3933

Query: 269  HFHARGEFNLMNLD----YEGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQ 324
               A G    +NLD    + G++    ++    P      R  +     +G+E       
Sbjct: 3934 SGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQE-----LP 3988

Query: 325  FRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVS 384
              +  ++   +   + +  G  L    D    SN  Q G + +   AG     G +   S
Sbjct: 3989 LNSKPRSYAHIEESVDVSPGCFLTATED--CASNPCQNGGVCNPSPAG-----GYYCKCS 4041

Query: 385  LSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCK-SPLGGFQGCM 443
                  H  ++V+   +      G   + +GG  +   C     G +C+ SP    + C 
Sbjct: 4042 ALYIGTHCEISVNPCSSKPCLYGGTCVVDNGG--FVCQCRGLYTGQRCQLSPYCKDEPCK 4099

Query: 444  R----LISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFH 499
                   S+ G V    S  +G     SD+        D C  N C HG  C  +  ++H
Sbjct: 4100 NGGTCFDSLDGAVCQCDSGFRGERCQ-SDI--------DECSGNPCLHGALCENTHGSYH 4150

Query: 500  CNCTNTGYRGATCHNSIYEQ 519
            CNC++  YRG  C ++   Q
Sbjct: 4151 CNCSHE-YRGRHCEDAAPNQ 4169



 Score = 38.1 bits (87), Expect = 0.052
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 474  CGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRG---NT 530
            C +S  C    C++GG C  S     C C ++G+RG  C + I E S     H     NT
Sbjct: 4087 CQLSPYCKDEPCKNGGTCFDSLDGAVCQC-DSGFRGERCQSDIDECSGNPCLHGALCENT 4145

Query: 531  SGFYY 535
             G Y+
Sbjct: 4146 HGSYH 4150



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 52/229 (22%), Positives = 84/229 (36%), Gaps = 39/229 (17%)

Query: 879  PEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVI 938
            P V  GC          C  G +C   P      C   +     C    S      S V 
Sbjct: 3788 PPVHHGCEDDP------CPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVK 3841

Query: 939  YNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA 998
            Y   EN    +N          +MKL+  +     RT  T +++++      +Y S++  
Sbjct: 3842 YRLTEN----ENKL--------EMKLTMRL-----RTYSTHAVVMYARG--TDY-SILEI 3881

Query: 999  KNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSS 1058
             +G LQ  YK +    P +V+     + DGQ H + +        + +D     QVH +S
Sbjct: 3882 HHGRLQ--YKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLD-----QVHTAS 3934

Query: 1059 GTEFSAVKSLVL------GRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1101
            GT    +K+L L      G  +         +     GF GC+ ++ L+
Sbjct: 3935 GTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLN 3983


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 48/153 (31%), Positives = 79/153 (51%), Gaps = 12/153 (7%)

Query: 8   DPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVT 67
           DP ++A     ++  +   +S  P  ARL +      W+   +++YQWLQIDL +  ++T
Sbjct: 305 DPQITASSVLEWTDHTGQENSWKPKKARLKKPGPP--WAAFATDEYQWLQIDLNKEKKIT 362

Query: 68  AVATQGG--YGSSNWVTSYLLMFSDSGWNWKQYR----QEDSIWGFSGNANADSVVYYRL 121
            + T G      + +V++Y +++SD G  W  YR    ++D I  F GN +    V    
Sbjct: 363 GIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKI--FQGNKDYHQDVRNNF 420

Query: 122 QPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAY 154
            P I ARF+R  P +W  K  I M++E+ GC +
Sbjct: 421 LPPIIARFIRVNPTQWQQK--IAMKMELLGCQF 451


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 8/177 (4%)

Query: 14  LPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLV----SNKYQWLQIDLGERMEVTAV 69
           +P    ++SS+ S S    + RL+  +G G W P +     +  ++LQIDL     +T V
Sbjct: 41  IPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLV 100

Query: 70  ATQGGYGSSNWVT---SYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIK 126
            TQG +   + +     Y + +S  G  W  +R         GN+N   +    L+P I 
Sbjct: 101 GTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIV 160

Query: 127 ARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 183
           ARF+RFIP+  +    + MR+E++GC +   +V  +  +   +     S+  + D +
Sbjct: 161 ARFVRFIPVT-DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSV 216


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 8/177 (4%)

Query: 14  LPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLV----SNKYQWLQIDLGERMEVTAV 69
           +P    ++SS+ S S    + RL+  +G G W P +     +  ++LQIDL     +T V
Sbjct: 41  IPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLV 100

Query: 70  ATQGGYGSSNWVT---SYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIK 126
            TQG +   + +     Y + +S  G  W  +R         GN+N   +    L+P I 
Sbjct: 101 GTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIV 160

Query: 127 ARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 183
           ARF+RFIP+  +    + MR+E++GC +   +V  +  +   +     S+  + D +
Sbjct: 161 ARFVRFIPVT-DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSV 216


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 11/142 (7%)

Query: 21  SSSELSSSHGPGFARLNRRDGA-------GGWSPLVSNKYQWLQIDLGERMEVTAVATQG 73
           +SS L    G    RLN + GA       G W      + QW+++D       T V TQG
Sbjct: 402 ASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQG 461

Query: 74  GYGS--SNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLR 131
              S   ++VT++ + FS+    W  Y        F GN + D+ V   L   + ARF+R
Sbjct: 462 RDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIR 521

Query: 132 FIPLEWNPKGRIGMRIEVFGCA 153
             PL WN  G + MR+EV GC+
Sbjct: 522 IYPLTWN--GSLCMRLEVLGCS 541


>gi|33469935 EGF-like, fibronectin type III and laminin G domains
            isoform 3 [Homo sapiens]
          Length = 375

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 97/388 (25%), Positives = 144/388 (37%), Gaps = 76/388 (19%)

Query: 748  FKTTASSGVFLENL--GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHH 805
            F+  +  GV L +   G  DF+ I L    V  F FD G+G   +  + P    +  WH 
Sbjct: 7    FRPDSGDGVLLYSYDTGSKDFLSINLAGGHV-EFRFDCGSGTGVLRSEDPLTLGN--WHE 63

Query: 806  VRVERNMKEASLQVDQLTPKTQPAPADG-HVLLQLNSQLFVGGTATRQ---------RGF 855
            +RV R  K   LQVD+   K     A+G    ++ N+ +F+GG              + F
Sbjct: 64   LRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPF 121

Query: 856  LGCIRSLQLNGMTL----DLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 911
             G I+ + LN  T+    D      V     P  R  C+       +GG CR R  G+ C
Sbjct: 122  SGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCA-------HGGSCRPRKEGYDC 174

Query: 912  DCTFSAYTGPFCSN------EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 965
            DC    + G  C        EI  + G      Y   +N  + K  S            S
Sbjct: 175  DCPL-GFEGLHCQKAIIEAIEIPQFIGRS----YLTYDNPDILKRVSG-----------S 218

Query: 966  REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA---KNGSLQIRYKLNKYQEPDVVNFDF 1022
            R  +   F+TT    LLL+         S  I+   ++G+L   Y L       +VN  F
Sbjct: 219  RSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSF 278

Query: 1023 KNMADGQLHHIMINREEGVVFIEIDD---------NRRRQVHLSSGTEFSAVKSLVLGRI 1073
                DG+ H +   R+     I +DD            RQ++++       +K + L   
Sbjct: 279  N---DGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIAL--- 332

Query: 1074 LEHSDVDQDTALAGAQGFTGCLSAVQLS 1101
                     T     +G  GC+S   LS
Sbjct: 333  --------HTNRQYMRGLVGCISHFTLS 352



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 45/137 (32%), Positives = 66/137 (48%), Gaps = 17/137 (12%)

Query: 742 ADVSFFFKTTASSGVFLENLGI-----ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT 796
           ++V   FKTTA  G+ L          +DFI + LR   +V FS+++G+G   I V    
Sbjct: 220 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 277

Query: 797 HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGT------AT 850
            FND +WH V+  R+ +   + VD    +T  +P      L +N  L+VGG         
Sbjct: 278 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMR-QLNINGALYVGGMKEIALHTN 335

Query: 851 RQ--RGFLGCIRSLQLN 865
           RQ  RG +GCI    L+
Sbjct: 336 RQYMRGLVGCISHFTLS 352



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)

Query: 157 EVVDLDGKSSLLYRFDQ--KSLSPIKDIISLKFKTMQSDGILLHREG----PNGDHITLQ 210
           E+    G+S L Y      K +S  +  + ++FKT   DG+LL R      PN D I+L 
Sbjct: 194 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 253

Query: 211 LRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEH 266
           LR   L    N G       S + ++ +    +D  WH V   R G+    TVD++
Sbjct: 254 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDY 302



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 10/142 (7%)

Query: 378 GQWHSVSLSAKKNHLSVAVDGQ-MASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436
           G WH + +S    +  + VD Q +       G  QI      + GG P+     K    L
Sbjct: 59  GNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVL 118

Query: 437 GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496
             F G ++ I ++ + + +           S + +++   +  C+   C HGG C     
Sbjct: 119 KPFSGSIQKIILNDRTIHV------KHDFTSGVNVENA--AHPCVRAPCAHGGSCRPRKE 170

Query: 497 TFHCNCTNTGYRGATCHNSIYE 518
            + C+C   G+ G  C  +I E
Sbjct: 171 GYDCDCP-LGFEGLHCQKAIIE 191



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 11/154 (7%)

Query: 305 RSYLALPDFSGEEEVSAT-----FQFRTWNKAGLLLF---SELQLISGGILLFLSDGKLK 356
           RSYL   +    + VS +      +F+T  K GLLL+   S ++  S  I L L DG L 
Sbjct: 201 RSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV 260

Query: 357 SNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLG-PEQIYSG 415
            + Y  G   + I      NDG+WH V          + VD   A      G   Q+   
Sbjct: 261 FS-YNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNIN 319

Query: 416 GTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISIS 449
           G  Y GG  + +  +  +  + G  GC+   ++S
Sbjct: 320 GALYVGGMKEIALHTN-RQYMRGLVGCISHFTLS 352


>gi|33469931 EGF-like, fibronectin type III and laminin G domains
            isoform 2 [Homo sapiens]
          Length = 775

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 97/388 (25%), Positives = 144/388 (37%), Gaps = 76/388 (19%)

Query: 748  FKTTASSGVFLENL--GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHH 805
            F+  +  GV L +   G  DF+ I L    V  F FD G+G   +  + P    +  WH 
Sbjct: 407  FRPDSGDGVLLYSYDTGSKDFLSINLAGGHV-EFRFDCGSGTGVLRSEDPLTLGN--WHE 463

Query: 806  VRVERNMKEASLQVDQLTPKTQPAPADG-HVLLQLNSQLFVGGTATRQ---------RGF 855
            +RV R  K   LQVD+   K     A+G    ++ N+ +F+GG              + F
Sbjct: 464  LRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPF 521

Query: 856  LGCIRSLQLNGMTL----DLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 911
             G I+ + LN  T+    D      V     P  R  C+       +GG CR R  G+ C
Sbjct: 522  SGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCA-------HGGSCRPRKEGYDC 574

Query: 912  DCTFSAYTGPFCSN------EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 965
            DC    + G  C        EI  + G      Y   +N  + K  S            S
Sbjct: 575  DCPL-GFEGLHCQKAIIEAIEIPQFIGRS----YLTYDNPDILKRVSG-----------S 618

Query: 966  REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA---KNGSLQIRYKLNKYQEPDVVNFDF 1022
            R  +   F+TT    LLL+         S  I+   ++G+L   Y L       +VN  F
Sbjct: 619  RSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSF 678

Query: 1023 KNMADGQLHHIMINREEGVVFIEIDD---------NRRRQVHLSSGTEFSAVKSLVLGRI 1073
                DG+ H +   R+     I +DD            RQ++++       +K + L   
Sbjct: 679  N---DGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIAL--- 732

Query: 1074 LEHSDVDQDTALAGAQGFTGCLSAVQLS 1101
                     T     +G  GC+S   LS
Sbjct: 733  --------HTNRQYMRGLVGCISHFTLS 752



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 45/137 (32%), Positives = 66/137 (48%), Gaps = 17/137 (12%)

Query: 742 ADVSFFFKTTASSGVFLENLGI-----ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT 796
           ++V   FKTTA  G+ L          +DFI + LR   +V FS+++G+G   I V    
Sbjct: 620 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 677

Query: 797 HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGT------AT 850
            FND +WH V+  R+ +   + VD    +T  +P      L +N  L+VGG         
Sbjct: 678 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMR-QLNINGALYVGGMKEIALHTN 735

Query: 851 RQ--RGFLGCIRSLQLN 865
           RQ  RG +GCI    L+
Sbjct: 736 RQYMRGLVGCISHFTLS 752



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 59/236 (25%), Positives = 106/236 (44%), Gaps = 20/236 (8%)

Query: 290 SCSQPQSMPVTFLSSRSYLAL-PDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILL 348
           SCS+   +        SY+   P  +  +    T +FR   + GLLL+        G   
Sbjct: 145 SCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGD-- 202

Query: 349 FLSDGKLKSNL---YQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAP 405
           F+S   ++ +L   +  G   + I +  ++  G WH+V L   ++ L+  +  Q+ +  P
Sbjct: 203 FMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLY--RDGLNGLL--QLNNGTP 258

Query: 406 LLGPEQ-IYSGGTY----YFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQ 460
           + G  Q  YS  T+    Y GG P   +  +      GFQGC++ ++++G+ +D+     
Sbjct: 259 VTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPL 318

Query: 461 GSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQ-SWSTFHCNCTNTGYRGATCHNS 515
           G   + +D+   S GI D      C HGG C+     ++ C C   G++G  C ++
Sbjct: 319 GKALSGADVGECSSGICDEA---SCIHGGTCTAIKADSYICLCP-LGFKGRHCEDA 370



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 82/403 (20%), Positives = 160/403 (39%), Gaps = 62/403 (15%)

Query: 729  SYLHFPTFHGELSA-DVSFFFKTTASSGVFL----ENLGIADFIRIELRSPTVVTFSFDV 783
            SY+ F        A  ++  F+  A  G+ L       G  DF+ + +   ++  F F+ 
Sbjct: 161  SYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSL-QFRFNC 219

Query: 784  GNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQL 843
            G G     + S T      WH V + R+     LQ++  TP T  +    +  +   + L
Sbjct: 220  GTGV--AIIVSETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQ-YSKITFRTPL 276

Query: 844  FVGGTATR---------QRGFLGCIRSLQLNGMTLDLEE----RAQVTPEVQPGCRGHCS 890
            ++GG  +           RGF GC++SL +NG  +D+      +A    +V     G C 
Sbjct: 277  YLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICD 336

Query: 891  SYGKLCRNGGKCRE-RPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSK 949
                 C +GG C   +   + C C    + G  C +  +         I  F+E+     
Sbjct: 337  EAS--CIHGGTCTAIKADSYICLCPL-GFKGRHCEDAFTL-------TIPQFRESL---- 382

Query: 950  NSSSHAAS---FHGDMKLSREMIKFSFRTTRTPSLLLF-VSSFYKEYLSVIIAKNGSLQI 1005
               S+AA+         LS    + +FR      +LL+   +  K++LS+ +A  G ++ 
Sbjct: 383  --RSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLA-GGHVEF 439

Query: 1006 RYKLN------KYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSG 1059
            R+         + ++P         +  G  H + ++R      +++D  +  +     G
Sbjct: 440  RFDCGSGTGVLRSEDP---------LTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGG 490

Query: 1060 -TEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1101
             T+      + +G +  + DV +++ +   + F+G +  + L+
Sbjct: 491  FTQIKCNTDIFIGGVPNYDDVKKNSGV--LKPFSGSIQKIILN 531



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)

Query: 157 EVVDLDGKSSLLYRFDQ--KSLSPIKDIISLKFKTMQSDGILLHREG----PNGDHITLQ 210
           E+    G+S L Y      K +S  +  + ++FKT   DG+LL R      PN D I+L 
Sbjct: 594 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 653

Query: 211 LRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEH 266
           LR   L    N G       S + ++ +    +D  WH V   R G+    TVD++
Sbjct: 654 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDY 702



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 10/142 (7%)

Query: 378 GQWHSVSLSAKKNHLSVAVDGQ-MASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436
           G WH + +S    +  + VD Q +       G  QI      + GG P+     K    L
Sbjct: 459 GNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVL 518

Query: 437 GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496
             F G ++ I ++ + + +           S + +++   +  C+   C HGG C     
Sbjct: 519 KPFSGSIQKIILNDRTIHV------KHDFTSGVNVENA--AHPCVRAPCAHGGSCRPRKE 570

Query: 497 TFHCNCTNTGYRGATCHNSIYE 518
            + C+C   G+ G  C  +I E
Sbjct: 571 GYDCDCP-LGFEGLHCQKAIIE 591



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 11/154 (7%)

Query: 305 RSYLALPDFSGEEEVSAT-----FQFRTWNKAGLLLF---SELQLISGGILLFLSDGKLK 356
           RSYL   +    + VS +      +F+T  K GLLL+   S ++  S  I L L DG L 
Sbjct: 601 RSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV 660

Query: 357 SNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLG-PEQIYSG 415
            + Y  G   + I      NDG+WH V          + VD   A      G   Q+   
Sbjct: 661 FS-YNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNIN 719

Query: 416 GTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISIS 449
           G  Y GG  + +  +  +  + G  GC+   ++S
Sbjct: 720 GALYVGGMKEIALHTN-RQYMRGLVGCISHFTLS 752


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,019,958
Number of Sequences: 37866
Number of extensions: 2210014
Number of successful extensions: 6850
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 5442
Number of HSP's gapped (non-prelim): 1140
length of query: 1235
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1121
effective length of database: 13,930,794
effective search space: 15616420074
effective search space used: 15616420074
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.