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Search of human proteins with 14670268
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14670268 RD RNA-binding protein [Homo sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14670268 RD RNA-binding protein [Homo sapiens] 760 0.0
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 91 1e-18
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 91 2e-18
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 83 5e-16
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 82 1e-15
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-15
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 80 2e-15
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 79 5e-15
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 79 5e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 79 5e-15
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 79 7e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 76 6e-14
gi|125988409 RED protein [Homo sapiens] 75 1e-13
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 73 4e-13
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 72 6e-13
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 72 8e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 72 8e-13
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 72 1e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 72 1e-12
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 71 1e-12
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 70 3e-12
gi|52426743 cisplatin resistance-associated overexpressed protei... 70 3e-12
gi|19923485 cisplatin resistance-associated overexpressed protei... 70 3e-12
gi|10190682 chromobox homolog 8 [Homo sapiens] 70 4e-12
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 69 7e-12
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 69 7e-12
gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 69 7e-12
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens] 69 7e-12
gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens] 69 7e-12
gi|213385278 TNF receptor-associated factor 3 interacting protei... 69 9e-12
>gi|14670268 RD RNA-binding protein [Homo sapiens]
Length = 380
Score = 760 bits (1963), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTAT 60
MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTAT
Sbjct: 1 MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTAT 60
Query: 61 ATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDL 120
ATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDL
Sbjct: 61 ATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDL 120
Query: 121 QESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA 180
QESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA
Sbjct: 121 QESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA 180
Query: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR
Sbjct: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
Query: 241 DREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFV 300
DREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFV
Sbjct: 241 DREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFV 300
Query: 301 TYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDAATGKSVWGSLAVQNSPKGCHRD 360
TYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDAATGKSVWGSLAVQNSPKGCHRD
Sbjct: 301 TYEKMESADQAVAELNGTQVESVQLKVNIARKQPMLDAATGKSVWGSLAVQNSPKGCHRD 360
Query: 361 KRTQIVYSDDVYKENLVDGF 380
KRTQIVYSDDVYKENLVDGF
Sbjct: 361 KRTQIVYSDDVYKENLVDGF 380
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 91.3 bits (225), Expect = 1e-18
Identities = 41/83 (49%), Positives = 63/83 (75%), Gaps = 6/83 (7%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R R+RS +RN+DR R RE+ RDR+R+R+RER+R+R+R+R+R+RER+R+RER+R+R+RE
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 244 GPFRR------SDSFPERRAPRK 260
+R D++ R+ RK
Sbjct: 427 KDKKRDREEDEEDAYERRKLERK 449
Score = 90.1 bits (222), Expect = 3e-18
Identities = 40/72 (55%), Positives = 51/72 (70%)
Query: 172 ERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERD 231
ER R R R+R E+ ++R+R+RERDRDRDR ++R+RDRDR+RDRDRDRER
Sbjct: 315 ERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERS 374
Query: 232 RDRERDRDRDRE 243
DR +DR R RE
Sbjct: 375 SDRNKDRSRSRE 386
Score = 89.7 bits (221), Expect = 4e-18
Identities = 75/263 (28%), Positives = 122/263 (46%), Gaps = 29/263 (11%)
Query: 11 EEEALQKKFNKLKKKKKALLALKKQSSSST---TSQGGVKRSLSEQPVMDTATATEQAKQ 67
E++ L K K K + A KK S+ + T + +L E+ T++ Q
Sbjct: 154 EKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEE--------TKRRDQ 205
Query: 68 LVKSGAISAIKAE---------TKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADD 118
++K GAI + E ++ R + E K + PV P+ + +
Sbjct: 206 MIK-GAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYP--LITKE 262
Query: 119 DLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHS 178
D+ ++ L +S + R+ EE +G + + + ER
Sbjct: 263 DINAIEMEEDKRDLISREIS---KFRDTHKKLEEEKGKKEKER--QEIEKERRERERERE 317
Query: 179 SASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDR 238
R R R+R ER R+++++RER+R+RDRDRDR ++RDRDRDR+RDR+RDR+R DR
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDR 377
Query: 239 DRDREGPFRRS-DSFPERRAPRK 260
++DR +S D ER R+
Sbjct: 378 NKDRSRSREKSRDRERERERERE 400
Score = 89.4 bits (220), Expect = 5e-18
Identities = 38/60 (63%), Positives = 51/60 (85%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R RDR+ ER+RDRDR+R+RDRDR+R DR +DR R R++ RDRER+R+RER+R+R+RE
Sbjct: 347 RDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERE 406
Score = 87.0 bits (214), Expect = 2e-17
Identities = 36/60 (60%), Positives = 51/60 (85%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R++ RDR +R RDRDRDRER DR++DR R R++ RDR+R+R+RER+R+RER+R+R+RE
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412
Score = 86.7 bits (213), Expect = 3e-17
Identities = 36/60 (60%), Positives = 51/60 (85%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
+ R RDR ER+RDRDR+R DR++DR R RE+ RDR+R+R+R+RER+R+RER+R+R+RE
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERE 414
Score = 85.5 bits (210), Expect = 7e-17
Identities = 35/60 (58%), Positives = 52/60 (86%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R RDR ER+ DR++DR R R++ RDR+RER+R+R+R+R+R+RER+R+RER+R+R+RE
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 422
Score = 72.4 bits (176), Expect = 6e-13
Identities = 47/150 (31%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 111 QRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGY 170
+R + + +E R +R+ E +R RE D + + R D
Sbjct: 313 ERERERERERREREREREREREREK-EKERERERERDRDRDRTKERDRDRDRERDRDRDR 371
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRD----RERDRDRDRDRDRERDRDRDRDRDR 226
E S + S R +SRDR ER R+R+R+ RER+R+R+R+R+RER+R+R++D+ R
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431
Query: 227 DRERDRDRERDRDRDREGPFRRSDSFPERR 256
DRE D + +R R E R ++ + R
Sbjct: 432 DREEDEEDAYER-RKLERKLREKEAAYQER 460
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 14/107 (13%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRD----------RDRERDRD 233
R R R+R ER R++D+ R+R+ D + +R + + R+++ RER +
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472
Query: 234 RERDRDRDREGPFRRSDSFPERRAPRKGNTLYVYGEDM-TPTLLRGA 279
RE +++ +RE RR + + A R L Y +D P RG+
Sbjct: 473 REYEKEAEREEERRREMA---KEAKRLKEFLEDYDDDRDDPKYYRGS 516
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 27/172 (15%)
Query: 88 RSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELG 147
RSR+ E K +D E+ + +R + + + R + + D+ R+
Sbjct: 381 RSRSRE-KSRDRERE-----REREREREREREREREREREREREREREREREKDKKRDRE 434
Query: 148 PDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRD 207
D E+A + R + Y+ER R R + R +E+ +R+ +R R+
Sbjct: 435 EDEEDAYERRKLERKLREKEAAYQERLKNWEI----RERKKTREYEKEAEREEERRREMA 490
Query: 208 RDRDRDRE--RDRDRDRD--------------RDRDRERDRDRERDRDRDRE 243
++ R +E D D DRD RDR++E + D ERDR R++E
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD-ERDRKREKE 541
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 90.5 bits (223), Expect = 2e-18
Identities = 41/77 (53%), Positives = 58/77 (75%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R R+R ER +R+R RER+R+R+++RDRERDRDRD DR+R+RER+RDRE++R+R+RE
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 244 GPFRRSDSFPERRAPRK 260
R + ER R+
Sbjct: 755 ERERERERERERERERE 771
Score = 88.6 bits (218), Expect = 9e-18
Identities = 42/83 (50%), Positives = 59/83 (71%), Gaps = 6/83 (7%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRD------RDRDRERDRDRDRDRDRDRERDRDRERD 237
R R RDR ER R+R+RDRER+++R+ R+R+RER+++RDR+RDRDR+ DR+RER+
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 238 RDRDREGPFRRSDSFPERRAPRK 260
R+RDRE R ER R+
Sbjct: 741 RERDREKEREREREERERERERE 763
Score = 87.8 bits (216), Expect = 1e-17
Identities = 36/60 (60%), Positives = 54/60 (90%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R+R RDR ER+R+R+R+RER+RDR+R+++RE +R+R R+R+R+RE++RDRERDRDRD +
Sbjct: 675 RARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHD 734
Score = 85.5 bits (210), Expect = 7e-17
Identities = 36/77 (46%), Positives = 58/77 (75%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R RDR E+ R+ +R+R R+R+R+R+++R+R+RDRDRD DR+RER+R+R+R+++R+RE
Sbjct: 693 RERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERE 752
Query: 244 GPFRRSDSFPERRAPRK 260
R + ER R+
Sbjct: 753 REERERERERERERERE 769
Score = 83.2 bits (204), Expect = 4e-16
Identities = 36/77 (46%), Positives = 56/77 (72%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R R++ E R+R R+RER+R+++RDR+R+RDRD DR+R+R+RERDR++ER+R+R+
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 244 GPFRRSDSFPERRAPRK 260
R + ER R+
Sbjct: 757 ERERERERERERERERE 773
Score = 81.6 bits (200), Expect = 1e-15
Identities = 54/191 (28%), Positives = 92/191 (48%), Gaps = 16/191 (8%)
Query: 80 ETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRK-----SLYE 134
+ ++S F+R + + E+ P+ P + +D+L+ RR +R+ +
Sbjct: 616 QARDSSFERRHGERDRRDNRERDQRPS-SPIRHQ-GRNDELERDERREERRVDRVDDRRD 673
Query: 135 SFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHER 194
DR RE + E + + E R R RDR +
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 195 NRDRDRDRERDRD---------RDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP 245
+R+R+R+RERDR+ R+R+R+RER+R+R+R+R+R+R R+RD+ER+R RD E
Sbjct: 734 DRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDK 793
Query: 246 FRRSDSFPERR 256
+ D E+R
Sbjct: 794 DKGRDDRREKR 804
Score = 81.3 bits (199), Expect = 1e-15
Identities = 66/217 (30%), Positives = 108/217 (49%), Gaps = 30/217 (13%)
Query: 63 EQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQE 122
E ++ +++ + + ++E +N RSR +L PEKG + S S++ + +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPEL--PEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 123 S----------SRRPQRKSLYESFVSSSDRL---RELGPDGEEAEGP-------GAGDGP 162
S R P+R + ++ SS +R R+ + E + P G D
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL 654
Query: 163 PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDR 222
R E R R R R +R R+RDR+RER+R+R+RDR+RE++R+ +R
Sbjct: 655 ERD-----ERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 223 DRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPR 259
+R R+RER+R++ERDR+RDR+ R D ER R
Sbjct: 710 ERAREREREREKERDRERDRD---RDHDRERERERER 743
Score = 74.3 bits (181), Expect = 2e-13
Identities = 47/119 (39%), Positives = 69/119 (57%), Gaps = 7/119 (5%)
Query: 128 QRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRS 187
+RKS + + + R D +++ + P S D RSG+ S R +
Sbjct: 1246 ERKSRIDQ-LKRGEPSRSTSSDRQDSRSHSSRRSSPES-DRQVHSRSGSFDSRD--RLQE 1301
Query: 188 RDR-SHERNRDRDR--DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
RDR H+R R+R+R R+R+ DRD D+D R+RDRDR R+R+RER+RD+ RD DR+RE
Sbjct: 1302 RDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1360
Score = 69.3 bits (168), Expect = 5e-12
Identities = 52/160 (32%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 112 RSISADDDLQESSRRPQRKSLYESFVSSSD-----RLRELGPDGEE-AEGPGAGDGPPRS 165
RS +L E R R S +S S+S+ R P+ + E S
Sbjct: 562 RSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSS 621
Query: 166 FDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRER-----DRDRDRDRDRERDRDR 220
F+ + ER + R S R RN + +RD R DR DR +R R+RDR
Sbjct: 622 FERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR 681
Query: 221 DRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
+R+RDR+RER+R+RERDR+R++E R + R K
Sbjct: 682 ERERDRERERERERERDREREKERELERERAREREREREK 721
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/86 (43%), Positives = 54/86 (62%), Gaps = 14/86 (16%)
Query: 184 RSRSRDRS-------HERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRER 236
R R RDR ER R+R+R+RER+R+R+R+R+R R+RD++R+R RD E D+D+ R
Sbjct: 739 RERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE-DKDKGR 797
Query: 237 DRDRDREGPFRRSDSFPERRAPRKGN 262
D R++ R E R PR G+
Sbjct: 798 DDRREKREEIR------EDRNPRDGH 817
Score = 57.8 bits (138), Expect = 2e-08
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRER 230
+ER R R R+R ER R+R+R RERD++R+R RD E D+D+ RD RE+
Sbjct: 747 KEREREREERERERERERERERERERERERARERDKERERQRDWE---DKDKGRDDRREK 803
Query: 231 DRDRERDR-------DRDREGPFRRSDSFPERRAPRK 260
+ DR +R + +R S R++P++
Sbjct: 804 REEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR 840
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/248 (24%), Positives = 95/248 (38%), Gaps = 18/248 (7%)
Query: 9 SEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQL 68
S + + KK K LL ++ S ++ + + G + P+ + ++ K+
Sbjct: 224 SPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEK 283
Query: 69 VK-SGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVP------TFQPFQRSISADDDLQ 121
K I + K+ G R E + K P + + S + +Q
Sbjct: 284 YKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQ 343
Query: 122 ESSRRPQRKSL----YESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAH 177
S P+RK Y+ ++ R P PPR E+ H
Sbjct: 344 RHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDH 403
Query: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE-RD-RDRE 235
S +S DR HER D R+R++D +R+ E+D+ RD DRE RD RDR
Sbjct: 404 ERTS----QSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRR 459
Query: 236 RDRD-RDR 242
RD RDR
Sbjct: 460 DARDTRDR 467
Score = 47.0 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 184 RSRSRDRSHERNRDRDRDRE-RDRDRDRDRDRERDRDRDRDR------DRDRERDRDRER 236
R R R+R+ ER+++R+R R+ D+D+ RD RE+ + DR D + + R R
Sbjct: 770 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 237 DRDRDREGPFRRSDSFPERRAPRKGN 262
R+ P RR + P+ A G+
Sbjct: 830 GSPSPRQSPKRRREHSPDSDAYNSGD 855
Score = 46.2 bits (108), Expect = 5e-05
Identities = 76/283 (26%), Positives = 113/283 (39%), Gaps = 57/283 (20%)
Query: 5 PPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQ 64
PP E+ AL KK+ K+K K +++++ +R ++ D +T
Sbjct: 266 PPPPIPEDIALGKKY---KEKYKVKDRIEEKTRDGKDRGRDFERQREKR---DKPRSTSP 319
Query: 65 AKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDP--EKGPVPTFQ-----PFQRSISAD 117
A Q S I + +S + +++ P ++ P P++Q P +RS S
Sbjct: 320 AGQ-----HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPY 374
Query: 118 DDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAH 177
SS PQRK +S +RE G E +S D +E R
Sbjct: 375 PSHSLSS--PQRK---QSPPRHRSPMREKGRHDHERTS--------QSHDRRHERREDTR 421
Query: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRD-RD-RDRDRERD-RDRDRDRD--------- 225
+ +R +E+++ RD DR+ RD RDR RD RDR RD
Sbjct: 422 GKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSRE 481
Query: 226 -RDRERDRDRERD-RD----------RDREG--PFRRSDSFPE 254
RD RD RD RD RDREG R+ D++PE
Sbjct: 482 MRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPE 524
Score = 30.4 bits (67), Expect = 2.8
Identities = 54/236 (22%), Positives = 76/236 (32%), Gaps = 30/236 (12%)
Query: 35 QSSSSTTSQGGVKRSLSE----QPVMDTATATEQAKQLVKSGAISAIKAETKNSGFKRSR 90
+ +++ T+ G LS P + TATAT L + A +A T S
Sbjct: 1082 EHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSA 1141
Query: 91 TLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDG 150
T P TF A++D R + + + V+ D D
Sbjct: 1142 T-------PTNTTNNTF--------ANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQ 1186
Query: 151 EEAEGPGAG-------DGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRE 203
+ + G+ G RS RSG S S R E+ + + E
Sbjct: 1187 KRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGE 1246
Query: 204 RDRDRDRDRDRERDRDRDRDRDRDRERDRDR---ERDRD-RDREGPFRRSDSFPER 255
R D+ + E R DR R R E DR R G F D ER
Sbjct: 1247 RKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQER 1302
Score = 28.9 bits (63), Expect = 8.0
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 11/87 (12%)
Query: 188 RDRSHERNRDRDRDRERD-RDRDRDRDRE--RDRD-RDRDRDRDRERDRDRERDRDRDRE 243
RD R+ RD RD RD RD RDR+ RD R D + R R+ RE
Sbjct: 477 RDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 244 GPFR-------RSDSFPERRAPRKGNT 263
R R++S E R R G +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRS 563
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 82.8 bits (203), Expect = 5e-16
Identities = 67/223 (30%), Positives = 87/223 (39%), Gaps = 33/223 (14%)
Query: 64 QAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQES 123
QA Q++K G ++ + ++ R E P P A D +E
Sbjct: 2014 QAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREG 2073
Query: 124 SRRPQRKSLYESFVSSSDRLRE---LGPDGEEAEGPGA--------------GDGPPRSF 166
R +E R RE +GP + E P A G R
Sbjct: 2074 KGHEYRNQTFEG------RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRER 2127
Query: 167 DWGYEERSGAHSSASPPRSRSRDRSHERNRDR----------DRDRERDRDRDRDRDRER 216
DW H R R+R NRDR DR RER R+R+R+RDR R
Sbjct: 2128 DWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRR 2187
Query: 217 DRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPR 259
DRDR R R+RDR++ RDRER RDR + S P+ A R
Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 81.6 bits (200), Expect = 1e-15
Identities = 39/74 (52%), Positives = 52/74 (70%), Gaps = 2/74 (2%)
Query: 172 ERSGAHSSASPPR--SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
ER A S + R R R R ERNR+RDRDRER++ DR+ +R+R+R+RDRDR R+ E
Sbjct: 30 ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETE 89
Query: 230 RDRDRERDRDRDRE 243
R+RD+ER+ DR E
Sbjct: 90 RERDKERETDRHTE 103
Score = 79.3 bits (194), Expect = 5e-15
Identities = 35/76 (46%), Positives = 53/76 (69%)
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREG 244
S++ DR ER+R RDR+R R+RDRDR+R+++ DR+ +R R+R+R+RDR RE +R+RD+E
Sbjct: 37 SKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKER 96
Query: 245 PFRRSDSFPERRAPRK 260
R R +K
Sbjct: 97 ETDRHTETDRERQKQK 112
Score = 78.2 bits (191), Expect = 1e-14
Identities = 36/64 (56%), Positives = 47/64 (73%), Gaps = 4/64 (6%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDR----D 239
R R RDR R RDRDR+RE+ DR+ +R RER+RDRDR R+ +RERD++RE DR D
Sbjct: 46 RDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105
Query: 240 RDRE 243
R+R+
Sbjct: 106 RERQ 109
Score = 75.5 bits (184), Expect = 7e-14
Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 12/104 (11%)
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDR-----------ERDRDRDRDRDRERDRD 219
E ++ + + + R R R DR+RDR ERDR RDR+R+RERDRD
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 220 RDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
R+R++ DRE +R RER+RDRDR+ R + ER R T
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETER-ERDKERETDRHTET 104
Score = 73.9 bits (180), Expect = 2e-13
Identities = 30/60 (50%), Positives = 45/60 (75%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R RDR E+ DR+ +R+R+R+RDRDR RE +R+RD++R+ DR + DRER + ++RE
Sbjct: 56 RERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE 115
Score = 71.2 bits (173), Expect = 1e-12
Identities = 36/100 (36%), Positives = 58/100 (58%), Gaps = 3/100 (3%)
Query: 164 RSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRD 223
R D E+++ R R RDR E R+RD++RE DR + DR+R++ ++R+ +
Sbjct: 58 RDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREME 117
Query: 224 RDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
R RDRER++ +E R+R + R +D ER+A R+ T
Sbjct: 118 RVRDREREKQKEMGRERQTD---RETDRERERQAERERET 154
Score = 68.2 bits (165), Expect = 1e-11
Identities = 38/103 (36%), Positives = 57/103 (55%), Gaps = 13/103 (12%)
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRD------RERDRDRDRDRDRERDRDRDRD- 223
E + H+ R + ++R ER RDR+R+ RER DR+ DR+RER +R+R+
Sbjct: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154
Query: 224 ------RDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
DR RER+R+R+R+R+R RE R + ER R+
Sbjct: 155 GRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRE 197
Score = 63.5 bits (153), Expect = 3e-10
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 14/142 (9%)
Query: 111 QRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGP-PRSFDWG 169
QR D D Q + R + K + +DR R+ +E E D + + G
Sbjct: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQ---KQKEREMERVRDREREKQKEMG 131
Query: 170 YEERSGAHSSASPPRSRSRDR-------SHERNRDRDRDRERDRDRDRD---RDRERDRD 219
E ++ + R R+R + +R+R+R+R+R+R+R+R R+ R+R D +
Sbjct: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
Query: 220 RDRDRDRDRERDRDRERDRDRD 241
R+R R+ DR+RDR RE +R+RD
Sbjct: 192 RERQRETDRKRDRQRESERERD 213
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 80.5 bits (197), Expect = 2e-15
Identities = 36/77 (46%), Positives = 56/77 (72%), Gaps = 3/77 (3%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R RDR ER RDRDR++ER+R ++DRD +R+ + +R+RDR+RE+ ++RE +RDRDR+
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
Query: 244 GPFRRSDSFPERRAPRK 260
R ++ ER+ R+
Sbjct: 193 ---RDTEKERERQTDRE 206
Score = 74.7 bits (182), Expect = 1e-13
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 11/149 (7%)
Query: 121 QESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA 180
++ R+ R+ + ++ +R RE + E G R D G E
Sbjct: 92 RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
Query: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
R +DR +R + +R+R+R+R++ ++R+ ERDRDR RD +++RER DRERDR R
Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
Query: 241 ----------DREGPFRRSDSFPERRAPR 259
DREG R +D ER+ R
Sbjct: 212 KTQTERQRETDREGE-RETDRRRERQRDR 239
Score = 72.4 bits (176), Expect = 6e-13
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 111 QRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGY 170
Q I D + ++ R + + DR +E E+ R D
Sbjct: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDRER----------DRDRDRDRDRERDRDR 220
E++ + R R ++ ER DR+RDR+R DR+ +R+ DR R+R R
Sbjct: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237
Query: 221 DRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLYVYGEDMTP 273
DRDR ++R+R+RDR+ +R ++R+ ++ ++ R+ + +GE ++P
Sbjct: 238 DRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 67.0 bits (162), Expect = 3e-11
Identities = 42/103 (40%), Positives = 63/103 (61%), Gaps = 11/103 (10%)
Query: 163 PRSFDWGYEERSGAHSSAS-PPRSRSRDRSHERN-RDRDRDRERDRDR---DRDRDRERD 217
PRS WG + AH A R R RDR E+ ++RDRDR+RDR+R +++ +R RD
Sbjct: 60 PRS--WGLGQ---AHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD 114
Query: 218 RDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
R++ + +RDRER++ + R+R+RDR G R D E+ R+
Sbjct: 115 REKQTEIERDREREKQKGRERERDR-GRERERDRDREKERERQ 156
Score = 63.2 bits (152), Expect = 4e-10
Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 30/99 (30%)
Query: 175 GAHSSASPPRSRSRDRSHERNRDRDRDRERD---------RDRDRDRDR----------- 214
G S PRS ++H+ DR RERD RDRDR RDR
Sbjct: 52 GRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNR 111
Query: 215 ----------ERDRDRDRDRDRDRERDRDRERDRDRDRE 243
ERDR+R++ + R+RERDR RER+RDRDRE
Sbjct: 112 NRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE 150
Score = 38.1 bits (87), Expect = 0.013
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 212 RDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
+D + D DR R+RDR RE+ ++ERDRDR R+ RR + R R+ T
Sbjct: 70 KDADGD-DRQRERDRVREKT-EKERDRDRKRDRERRRKEKETNRNRDREKQT 119
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 80.5 bits (197), Expect = 2e-15
Identities = 46/123 (37%), Positives = 70/123 (56%), Gaps = 8/123 (6%)
Query: 140 SDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRD 199
S R R LG ++A+G + + E+R + R R+R E++R R
Sbjct: 36 SPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERET-----DRKRERRREKDRHRK 90
Query: 200 RDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP---FRRSDSFPERR 256
RDR R+R RDR+++RER DR+RDR R++ER+R +ER+R+ +REG R++D ER
Sbjct: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 257 APR 259
R
Sbjct: 151 RQR 153
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/186 (30%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Query: 78 KAETKNS--GFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYES 135
K E ++S G +R R E + + K + QR + + Q R +
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 136 FVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERN 195
+R R+ D + E R D + R+ R R R+R ER
Sbjct: 260 KERERERDRDRDRDRRQKERE-------RQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 196 RDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRER--DRDRERDRDRDREGPFRRSDSFP 253
R+R R+RER+R+R+R+R RE +RDR+++R+R R+R + DRER+R REG R+++
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR-RQAERER 371
Query: 254 ERRAPR 259
ER R
Sbjct: 372 ERERER 377
Score = 77.4 bits (189), Expect = 2e-14
Identities = 36/77 (46%), Positives = 53/77 (68%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R RDR ER R+R R+RER+R+R+R R+RER+R+R+R+R R+ ERDR++ER+R R R+
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Query: 244 GPFRRSDSFPERRAPRK 260
R + R R+
Sbjct: 349 TEMDRERNRQTGREGRR 365
Score = 77.0 bits (188), Expect = 3e-14
Identities = 44/112 (39%), Positives = 59/112 (52%), Gaps = 22/112 (19%)
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDR-------------------ERDRDRDRD 211
E A + R RD+ ER RDRDRDR ERDR+ +R
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 212 RDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
R+R+R+R+R+R+R+R RER+R+RER+R+R RE D ER RK T
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRE---TERDREKERERKRKRQT 349
Score = 76.3 bits (186), Expect = 4e-14
Identities = 34/76 (44%), Positives = 52/76 (68%)
Query: 186 RSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP 245
R R R ER+R+ +R RER R+R+R+R+R R R+R+R+R+R+RER R+ ERDR+++RE
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 246 FRRSDSFPERRAPRKG 261
+R R + G
Sbjct: 345 RKRQTEMDRERNRQTG 360
Score = 75.1 bits (183), Expect = 1e-13
Identities = 39/93 (41%), Positives = 55/93 (59%), Gaps = 6/93 (6%)
Query: 177 HSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDR------DRDRDRER 230
HS R R R+ E R R DRERDR R +R+RE+ +R+R +RD++RER
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
Query: 231 DRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
+RDR+RDRDR ++ R++D +RR R T
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Score = 75.1 bits (183), Expect = 1e-13
Identities = 41/97 (42%), Positives = 62/97 (63%), Gaps = 7/97 (7%)
Query: 172 ERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERD 231
ER SA R RDR +R ++R+R E+DRD R+ +++R+R++DR+ +R RER
Sbjct: 374 ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
Query: 232 RDRERD--RDRDREGPFRRSDSFPERRAPRKGNTLYV 266
R+RE+ R+RDRE R++D R+ RK +TLYV
Sbjct: 434 REREKQKGRERDRE---RQTDRQAGRQ--RKRSTLYV 465
Score = 71.6 bits (174), Expect = 1e-12
Identities = 37/86 (43%), Positives = 55/86 (63%), Gaps = 3/86 (3%)
Query: 177 HSSASPPRSRSRDRSHERNR--DRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
H R R RDR ER R DR+RDR+R+++R+R ++RER+ +R+ +R RDR+ D R
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 235 ERDRDRDREGP-FRRSDSFPERRAPR 259
ER+R RD E R++D +R+ R
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTER 173
Score = 71.6 bits (174), Expect = 1e-12
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 12/92 (13%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDR------------DRERD 231
R+R R+R ER R+R+R RE +RDR+++R+R+R R + DR+R +RER+
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 232 RDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
R+RERDR RE R D +R+ R+ T
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQT 404
Score = 70.9 bits (172), Expect = 2e-12
Identities = 43/141 (30%), Positives = 69/141 (48%)
Query: 116 ADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSG 175
AD D +E +R+ +R+ E + + R+ E+ R D E
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQ 108
Query: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235
R + R+R ER R+ +R+ ER RDR D RER+R RD +++R+R+ DR+R+
Sbjct: 109 TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Query: 236 RDRDRDREGPFRRSDSFPERR 256
R +R+R+ R + ERR
Sbjct: 169 RQTERNRQKEREREKNRQERR 189
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/191 (29%), Positives = 86/191 (45%), Gaps = 26/191 (13%)
Query: 80 ETKNSGFK-RSRTLEG-----KLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLY 133
ET+ G + R R +G + +D EK +R D + Q + R ++K
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEK---------ERERQTDRERQRQTERNRQKERE 180
Query: 134 ESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHE 193
R RE + E R + G E + R R DR +
Sbjct: 181 REKNRQERRERERQREKENKT-------EDRHSERGRERERERETETETERKRQTDRERD 233
Query: 194 RNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR---ERDRDRDREGPFR-RS 249
R R +R+RE+ +R+R +RE +RD++R+R+RDR+RDRDR ER+R DR+ R
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 250 DSFPERRAPRK 260
D ER+ R+
Sbjct: 294 DRETERKRERQ 304
Score = 66.6 bits (161), Expect = 3e-11
Identities = 30/80 (37%), Positives = 49/80 (61%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R ER RD +++RER DR+R R ER+R ++R+R+++R+ R+RER R+++ +
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 244 GPFRRSDSFPERRAPRKGNT 263
R S+ ER R+ T
Sbjct: 201 TEDRHSERGRERERERETET 220
Score = 58.9 bits (141), Expect = 7e-09
Identities = 32/83 (38%), Positives = 51/83 (61%), Gaps = 4/83 (4%)
Query: 179 SASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRD-RERDRDRDRDRDRDRERDRDRERD 237
S PR R ++H+ DR+R R ++R+R R+ R+ +R+ DR R+R RE+DR R+RD
Sbjct: 33 SQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD 92
Query: 238 RDRDREGPFRRSDSFPERRAPRK 260
R R+R+ R + ER+ R+
Sbjct: 93 RHRERQ---RDREKERERQTDRE 112
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/80 (40%), Positives = 46/80 (57%), Gaps = 8/80 (10%)
Query: 185 SRSRDRSHERNRDRDRDR-ERDRDRDRDRDRERDRDRDRDRDR---DRERDRDRERDRDR 240
SR R S E R R + +D D D DR+R R ++R+R R++ +RE DR RER R++
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGD-DRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 241 DREGPFRRSDSFPERRAPRK 260
DR R+ D ER+ R+
Sbjct: 86 DRH---RKRDRHRERQRDRE 102
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 79.3 bits (194), Expect = 5e-15
Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 3/90 (3%)
Query: 172 ERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERD 231
ER H R R R E+ R+R ++R+R R R+R+ +RE +R R+R R R+R+R
Sbjct: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Query: 232 RDRERDRDRDREGPFRRSDSFPERRAPRKG 261
DRERD+DRDRE R+ ++ R RKG
Sbjct: 92 TDRERDKDRDRE---RKRETDRNRERNRKG 118
Score = 78.2 bits (191), Expect = 1e-14
Identities = 39/78 (50%), Positives = 53/78 (67%), Gaps = 1/78 (1%)
Query: 186 RSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP 245
R R+R +R R R DRERD+DRDR+R RE DR+R+R+R RERD+ ER+RDR+RE
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQ 137
Query: 246 FRRSDSFPERRAPRKGNT 263
R+ + +R+ RK T
Sbjct: 138 -RQRERERQRQRERKRET 154
Score = 77.8 bits (190), Expect = 2e-14
Identities = 36/77 (46%), Positives = 53/77 (68%), Gaps = 1/77 (1%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R + RDR +R R+ +R+ ER R+R R R+R+R DR+RD+DRDRER R+ +R+R+R+R+
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 244 GPFRRSDSFPERRAPRK 260
G R D ER R+
Sbjct: 118 GG-RERDKQTERERDRE 133
Score = 76.3 bits (186), Expect = 4e-14
Identities = 41/83 (49%), Positives = 54/83 (65%), Gaps = 7/83 (8%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRD------RERDRDRDRDRDRDRERDRDRERD 237
R R R R +R RD+DRDRER R+ DR+R+ RERD+ +R+RDR+RER R RER+
Sbjct: 84 RQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERE 143
Query: 238 RDRDREGPFRRSDSFPERRAPRK 260
R R RE R +D +R A R+
Sbjct: 144 RQRQRERK-RETDRERQRWAERE 165
Score = 74.7 bits (182), Expect = 1e-13
Identities = 32/60 (53%), Positives = 46/60 (76%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R R+R + +R+RD+DR+R+R R+ DR+RER+R R+RD+ ER+RDRER+R R RE
Sbjct: 82 RQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRE 141
Score = 74.7 bits (182), Expect = 1e-13
Identities = 35/83 (42%), Positives = 55/83 (66%), Gaps = 6/83 (7%)
Query: 184 RSRSRDRSHERNRDRDRDRER------DRDRDRDRDRERDRDRDRDRDRDRERDRDRERD 237
R R +DR ER R+ DR+RER +RD+ +R+R+R+R+R R R+R+R+R R+R+R+
Sbjct: 94 RERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE 153
Query: 238 RDRDREGPFRRSDSFPERRAPRK 260
DR+R+ R + ER+ RK
Sbjct: 154 TDRERQRWAEREERKKERKKERK 176
Score = 74.3 bits (181), Expect = 2e-13
Identities = 35/77 (45%), Positives = 50/77 (64%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R DR+ ERNR R+R++ +R+RDR+RER R R+R+R R RER R+ +R+R R E
Sbjct: 104 RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE 163
Query: 244 GPFRRSDSFPERRAPRK 260
R+ + ER+ RK
Sbjct: 164 REERKKERKKERKKERK 180
Score = 68.2 bits (165), Expect = 1e-11
Identities = 34/82 (41%), Positives = 54/82 (65%), Gaps = 8/82 (9%)
Query: 186 RSRDRSHERNRDRDRDRERDRDRDRD-------RDRERDRDRDRDRDRDRERDRDRERDR 238
R R+R E +R ++ +RERDR R+R+ R R+RDR R+RDR DRE++R+R+++R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 239 DRDREGPFRRSDSFPERRAPRK 260
DR R+ R ++ ER+ R+
Sbjct: 63 DRQRQRE-RETERETERQRERQ 83
Score = 65.1 bits (157), Expect = 1e-10
Identities = 32/91 (35%), Positives = 56/91 (61%), Gaps = 1/91 (1%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRER-DRDRDR 242
R R+R ER++ +R+R+R+R+R R R+RER R R+R R+ DRER R ER +R ++R
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
Query: 243 EGPFRRSDSFPERRAPRKGNTLYVYGEDMTP 273
+ ++ ++ R+ + +GE ++P
Sbjct: 172 KKERKKERKEKKKEEKRREDKKRKWGEGISP 202
Score = 57.4 bits (137), Expect = 2e-08
Identities = 26/78 (33%), Positives = 47/78 (60%), Gaps = 3/78 (3%)
Query: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDR 232
+ G R R R+R +R R+R+R R+R+R R+ DR+R+R +R+ +R +ER +
Sbjct: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE---ERKKERKK 173
Query: 233 DRERDRDRDREGPFRRSD 250
+R+++R ++ RR D
Sbjct: 174 ERKKERKEKKKEEKRRED 191
Score = 55.8 bits (133), Expect = 6e-08
Identities = 26/52 (50%), Positives = 37/52 (71%), Gaps = 5/52 (9%)
Query: 197 DRDRDRERDRDRDRDRDRERDRDRDRD-----RDRDRERDRDRERDRDRDRE 243
+R R+R+R+ DR ++ +RERDR R+R+ +R R+RDR RERDR DRE
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDRE 53
Score = 47.0 bits (110), Expect = 3e-05
Identities = 21/45 (46%), Positives = 29/45 (64%)
Query: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPER 255
+R RER R+ DR ++ +RERDR RER+ +RE R+ D ER
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRER 46
Score = 43.9 bits (102), Expect = 2e-04
Identities = 23/63 (36%), Positives = 39/63 (61%), Gaps = 10/63 (15%)
Query: 205 DRDRDRDRDRERDRDRDRDRDRDRERD-------RDRERDRDRDREGPFRRSDSFPERRA 257
+R R+R R+ +R ++ +R+RDR RER+ R R+RDR R+R+ R++D ER
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERD---RQTDREKERER 58
Query: 258 PRK 260
++
Sbjct: 59 QKE 61
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 79.3 bits (194), Expect = 5e-15
Identities = 46/146 (31%), Positives = 81/146 (55%), Gaps = 16/146 (10%)
Query: 124 SRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSS---- 179
SRR + +S + S S +R R D ++ P R + RS +HS
Sbjct: 324 SRRKRSQSKHRS--RSHNRSRSRQKDRRRSKSPHKKRSKSRE---RRKSRSRSHSRDKRK 378
Query: 180 ------ASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRD 233
R + +DR ER R+++R++E++R +++DRD+ER++DR++D+++DRER+R+
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438
Query: 234 RERDRDRDREGPFRRSDSFPERRAPR 259
+E ++DRD+E + D ER R
Sbjct: 439 KEHEKDRDKEKE-KEQDKEKEREKDR 463
Score = 79.0 bits (193), Expect = 7e-15
Identities = 59/258 (22%), Positives = 121/258 (46%), Gaps = 40/258 (15%)
Query: 5 PPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQ 64
P ++E E + K+ + + A A++ +S S +GG RS + ++ + +
Sbjct: 268 PQAAAKELEEVMKRVREAQSFISA--AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 325
Query: 65 AKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESS 124
K+ S K +++ RSR KD + P + +S S
Sbjct: 326 RKR-------SQSKHRSRSHNRSRSRQ-----KDRRRSKSP-HKKRSKSRERRKSRSRSH 372
Query: 125 RRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPR 184
R +RK E + +R++E + E +ER +
Sbjct: 373 SRDKRKDTREK-IKEKERVKEKDREKERERE---------------KERE---------K 407
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREG 244
+ R ++ +R+++R++DRE+D+++DR+R+RE++ ++DRD+++++E+D+++ER++DR +E
Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467
Query: 245 PFRRSDSFPERRAPRKGN 262
+R R PR N
Sbjct: 468 DEKRKKDKKSRTPPRSYN 485
Score = 38.1 bits (87), Expect = 0.013
Identities = 56/270 (20%), Positives = 102/270 (37%), Gaps = 42/270 (15%)
Query: 16 QKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAIS 75
QK + K K +++ S + S KR + + + + E+ ++ +
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404
Query: 76 AIKAETKNSGFKRSRTLE-GKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYE 134
K + + R + E + KD EK + +R + D + + Q K
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKD-----REREREKEHEKDRDKEKEKEQDKEKER 459
Query: 135 SFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAH----------------- 177
DR +E+ E+ + PPRS++ RS +
Sbjct: 460 E----KDRSKEID---EKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 512
Query: 178 ------SSASP-PRSRSR-DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
SS SP PRSR++ D+ E+ RD +R R+R+R R DRD E
Sbjct: 513 KTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSM---RKSSNDRDGKEKLE 568
Query: 230 RDRDRERDRDRDREGPFRRSDSFPERRAPR 259
++ ++++ ++E S ++ APR
Sbjct: 569 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 79.3 bits (194), Expect = 5e-15
Identities = 46/146 (31%), Positives = 81/146 (55%), Gaps = 16/146 (10%)
Query: 124 SRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSS---- 179
SRR + +S + S S +R R D ++ P R + RS +HS
Sbjct: 208 SRRKRSQSKHRS--RSHNRSRSRQKDRRRSKSPHKKRSKSRE---RRKSRSRSHSRDKRK 262
Query: 180 ------ASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRD 233
R + +DR ER R+++R++E++R +++DRD+ER++DR++D+++DRER+R+
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Query: 234 RERDRDRDREGPFRRSDSFPERRAPR 259
+E ++DRD+E + D ER R
Sbjct: 323 KEHEKDRDKEKE-KEQDKEKEREKDR 347
Score = 79.0 bits (193), Expect = 7e-15
Identities = 59/258 (22%), Positives = 121/258 (46%), Gaps = 40/258 (15%)
Query: 5 PPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQ 64
P ++E E + K+ + + A A++ +S S +GG RS + ++ + +
Sbjct: 152 PQAAAKELEEVMKRVREAQSFISA--AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 209
Query: 65 AKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESS 124
K+ S K +++ RSR KD + P + +S S
Sbjct: 210 RKR-------SQSKHRSRSHNRSRSRQ-----KDRRRSKSP-HKKRSKSRERRKSRSRSH 256
Query: 125 RRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPR 184
R +RK E + +R++E + E +ER +
Sbjct: 257 SRDKRKDTREK-IKEKERVKEKDREKERERE---------------KERE---------K 291
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREG 244
+ R ++ +R+++R++DRE+D+++DR+R+RE++ ++DRD+++++E+D+++ER++DR +E
Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351
Query: 245 PFRRSDSFPERRAPRKGN 262
+R R PR N
Sbjct: 352 DEKRKKDKKSRTPPRSYN 369
Score = 38.1 bits (87), Expect = 0.013
Identities = 56/270 (20%), Positives = 102/270 (37%), Gaps = 42/270 (15%)
Query: 16 QKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAIS 75
QK + K K +++ S + S KR + + + + E+ ++ +
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288
Query: 76 AIKAETKNSGFKRSRTLE-GKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYE 134
K + + R + E + KD EK + +R + D + + Q K
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKD-----REREREKEHEKDRDKEKEKEQDKEKER 343
Query: 135 SFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAH----------------- 177
DR +E+ E+ + PPRS++ RS +
Sbjct: 344 E----KDRSKEID---EKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 396
Query: 178 ------SSASP-PRSRSR-DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
SS SP PRSR++ D+ E+ RD +R R+R+R R DRD E
Sbjct: 397 KTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSM---RKSSNDRDGKEKLE 452
Query: 230 RDRDRERDRDRDREGPFRRSDSFPERRAPR 259
++ ++++ ++E S ++ APR
Sbjct: 453 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 482
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 79.0 bits (193), Expect = 7e-15
Identities = 39/79 (49%), Positives = 54/79 (68%), Gaps = 7/79 (8%)
Query: 172 ERSGAHSSASPPRSRSRDRSHERNRDRDRDRER---DRDRDRDRDRERDRDRDRDR---- 224
ER + R R R + E RDRDR+R+R DR+RDRDR +ER++DR R+R
Sbjct: 163 EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
Query: 225 DRDRERDRDRERDRDRDRE 243
DRD+ERDR+R+R++DRDR+
Sbjct: 223 DRDKERDRERQREKDRDRQ 241
Score = 76.3 bits (186), Expect = 4e-14
Identities = 41/85 (48%), Positives = 55/85 (64%), Gaps = 3/85 (3%)
Query: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERD 237
S +P R R+R ER R R R +ER R++DR+ +++RDR R RDR+R R RDRDR+R+
Sbjct: 50 SRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE 109
Query: 238 R--DRDREGPFRRSDSFPERRAPRK 260
R DRDRE R + ER+ RK
Sbjct: 110 RWGDRDRETETERQEE-RERQRDRK 133
Score = 71.2 bits (173), Expect = 1e-12
Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 16/93 (17%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDR----- 238
R R R R ER R RDRDR+R+R DRDR+ E +R +R+R RDR+R++DRER R
Sbjct: 88 RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIG 147
Query: 239 -----------DRDREGPFRRSDSFPERRAPRK 260
DRDRE ++ + +R R+
Sbjct: 148 IDKDREIETEKDRDREREMGETERYRDRERERQ 180
Score = 71.2 bits (173), Expect = 1e-12
Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 14/105 (13%)
Query: 168 WGYEERSGAHSSASPPRSRSRDRSHERNRDR--------DRDRERDRDRDRDRDRE---- 215
WG +R + R R RDR E++R+R D+DRE + ++DRDR+RE
Sbjct: 111 WGDRDRE-TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
Query: 216 -RDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPR 259
R RDR+R+R + RE RDR+R+R R++E R D ER R
Sbjct: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR 214
Score = 70.5 bits (171), Expect = 2e-12
Identities = 30/59 (50%), Positives = 48/59 (81%), Gaps = 1/59 (1%)
Query: 184 RSRSRDRSHER-NRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
R R R+R E+ +R+RDRDR+++R++DR R+RE RDRD++RDR+R+R++DR+R + D
Sbjct: 187 RDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
Score = 65.5 bits (158), Expect = 8e-11
Identities = 37/85 (43%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 184 RSRSRDRSHERNRDRDRD--------RERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235
R R RDR ER DRDR+ RER RDR R++DRER R R+ D+DRE + +++
Sbjct: 100 RWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD 159
Query: 236 RDRDRDREGPFRRSDSFPERRAPRK 260
RDR+R+ R D ER+ R+
Sbjct: 160 RDREREMGETERYRDRERERQKQRE 184
Score = 31.6 bits (70), Expect = 1.2
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 16/87 (18%)
Query: 121 QESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA 180
+E R+ QR++ DR RE + E+ E R D E +
Sbjct: 175 RERERQKQRET-------RRDRDRERQREKEDRE---------RDRDRQKEREKDRYRER 218
Query: 181 SPPRSRSRDRSHERNRDRDRDRERDRD 207
R R ++R ER R++DRDR++ D
Sbjct: 219 ETGRDRDKERDRERQREKDRDRQKAID 245
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 75.9 bits (185), Expect = 6e-14
Identities = 53/142 (37%), Positives = 73/142 (51%), Gaps = 15/142 (10%)
Query: 121 QESSRRPQRKSLYESFVSSSDRLRELGPDGE------EAEGPGAGDGPPRSFDWGYEERS 174
+ S RR + +S + SS REL + E EA+ RS D G E R
Sbjct: 270 RRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR 329
Query: 175 GAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
RSR R RS R+RDR DR RDRDR+R+++ ER R RDRD D++R +R++
Sbjct: 330 S--------RSRERHRSRSRSRDRKGDR-RDRDREREKENERGRRRDRDYDKERGNEREK 380
Query: 235 ERDRDRDREGPFRRSDSFPERR 256
ER+R R+R R E++
Sbjct: 381 ERERSRERSKEQRSRGEVEEKK 402
Score = 59.3 bits (142), Expect = 6e-09
Identities = 39/97 (40%), Positives = 52/97 (53%), Gaps = 16/97 (16%)
Query: 179 SASPPRS--RSRDRSHER--------NRDRDRDRERDR------DRDRDRDRERDRDRDR 222
S SP RS RSR RSH R +R+ +R++ER R +R+++R R R DR
Sbjct: 266 SLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGL 325
Query: 223 DRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPR 259
+R R R R+R R R R RDR+G R D E+ R
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/79 (39%), Positives = 41/79 (51%)
Query: 179 SASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDR 238
S SP RS S RS R+R R RE DR+ ER+++R R +ER+++R R R
Sbjct: 260 SRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSR 319
Query: 239 DRDREGPFRRSDSFPERRA 257
DR RRS S R+
Sbjct: 320 SIDRGLERRRSRSRERHRS 338
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 21/187 (11%)
Query: 87 KRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLREL 146
K + LE + K+ EK +RS S D L+ RR + + + S S DR +
Sbjct: 299 KERQRLEREAKEREKER-------RRSRSIDRGLER--RRSRSRERHRSRSRSRDRKGDR 349
Query: 147 GPDGEEAEGPGAGDGPPRSFDWGYE-------ERSGAHSSASPPRSRSRDRSHERNRDRD 199
E E G R D+ E ER + + RSR + D+D
Sbjct: 350 RDRDREREKENER-GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 200 RDRERDRDRDRDRDRERDRDRDRDR-DRDRERDRD---RERDRDRDREGPFRRSDSFPER 255
R RD RD ++++ R R R+R R R R R+ R R R +++ +
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSN 468
Query: 256 RAPRKGN 262
+ R G+
Sbjct: 469 KRSRSGS 475
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 164 RSFDWGYEERSGAHSSASPPRSRSRDRSHE-RNRDRDRDRERDRDRDRDR----DRERDR 218
RS + + RS + ++ RSRS+++S + +N +++ +R R + R ++ + R
Sbjct: 429 RSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKR 488
Query: 219 DRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRA 257
+ +++ R+R R +ER RD +SD RR+
Sbjct: 489 EHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRS 527
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 164 RSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRD 223
RS + G RS + +S ++ S+++S++R+R + R ++ + R+ +++ R
Sbjct: 440 RSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Query: 224 RDRDRERD--RDRERDRDRDREGPFRRSDSFPE 254
R R +ER RD +D+ + RRS S +
Sbjct: 500 RSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532
Score = 43.9 bits (102), Expect = 2e-04
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 171 EERSGAHSSASPPRSRSRDRSH--------ERNRDRDRDRERDRDRDRDRDRERDRDRDR 222
+E+S H + S +S R RS E+++ R+ +++ R R R +ER RD
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH 512
Query: 223 DRDRDRERDRDRERDRDRDRE 243
+D+ DR R + ++E
Sbjct: 513 SDSKDQSDKHDRRRSQSIEQE 533
Score = 38.5 bits (88), Expect = 0.010
Identities = 17/67 (25%), Positives = 32/67 (47%)
Query: 175 GAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
G S + R S E++R R R +ER RD +++ DR R + E++
Sbjct: 477 GRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQE 536
Query: 235 ERDRDRD 241
++ +++D
Sbjct: 537 KQHKNKD 543
Score = 38.1 bits (87), Expect = 0.013
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 172 ERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERD 231
++ G + R R RS R R R R R RE DR+ +RE++
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 232 RDRERDRDRDREGPFRRSDSFP---ERRAPR 259
R R ++RE RRS S ERR R
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRSR 331
Score = 37.7 bits (86), Expect = 0.017
Identities = 17/72 (23%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 173 RSGAHSSA-SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERD 231
RSG+ S +S+ R+ S + + R R R ++R RD +D+ DR R + +
Sbjct: 472 RSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIE 531
Query: 232 RDRERDRDRDRE 243
++ + + ++++
Sbjct: 532 QESQEKQHKNKD 543
Score = 35.8 bits (81), Expect = 0.066
Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 1/121 (0%)
Query: 111 QRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGY 170
+ S S + + SR R + S S ++ + + +E + G D
Sbjct: 424 KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRER 230
+ + HS S +SR R RS ER+ RD +D+ DR R + +++ + + +
Sbjct: 484 KSKKREHSP-SKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNK 542
Query: 231 D 231
D
Sbjct: 543 D 543
>gi|125988409 RED protein [Homo sapiens]
Length = 557
Score = 75.1 bits (183), Expect = 1e-13
Identities = 30/53 (56%), Positives = 46/53 (86%)
Query: 196 RDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
RD++R+R R+R+RDR+RDR+RDR+R+R+RDR+RER+RDRER+ ++ R F +
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEK 386
Score = 74.3 bits (181), Expect = 2e-13
Identities = 31/47 (65%), Positives = 42/47 (89%)
Query: 188 RDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
RD+ ER R+R+RDRERDRDRDR+R+RERDR+R+R+RDR+RE ++ R
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
Score = 72.8 bits (177), Expect = 5e-13
Identities = 31/64 (48%), Positives = 48/64 (75%)
Query: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERD 237
S+ PR + R+R ER RDR+RDR+RDR+R+R+RDRER+R+RDR+R+ +++R E+
Sbjct: 328 STTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
Query: 238 RDRD 241
+ D
Sbjct: 388 KVDD 391
Score = 72.0 bits (175), Expect = 8e-13
Identities = 30/54 (55%), Positives = 44/54 (81%)
Query: 183 PRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRER 236
P + R ER R R+R+R+R+RDRDRDR+RER+RDR+R+R+RDRER+ +++R
Sbjct: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
Score = 71.2 bits (173), Expect = 1e-12
Identities = 34/53 (64%), Positives = 44/53 (83%), Gaps = 2/53 (3%)
Query: 200 RDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSF 252
RD+ER+R R+R+RDRERD RDRDR+R+RERDR+RER+RDR+RE +R F
Sbjct: 334 RDKERERYRERERDRERD--RDRDRERERERDRERERERDREREEEKKRHSYF 384
Score = 70.5 bits (171), Expect = 2e-12
Identities = 30/53 (56%), Positives = 44/53 (83%)
Query: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP 245
++ R+R R+RERDR+RDRDRDRER+R+RDR+R+R+R+R+R+ E+ R E P
Sbjct: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
Score = 67.0 bits (162), Expect = 3e-11
Identities = 29/70 (41%), Positives = 47/70 (67%)
Query: 163 PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDR 222
P D E G + ++ R ++R R R+RDR+R+RDRDR+R+R+R+R+R+R+R
Sbjct: 311 PPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERER 370
Query: 223 DRDRDRERDR 232
DR+R+ E+ R
Sbjct: 371 DREREEEKKR 380
Score = 64.7 bits (156), Expect = 1e-10
Identities = 28/58 (48%), Positives = 41/58 (70%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
R R R+R +R RDRDRDRER+R+RDR+R+RERDR+R+ ++ R ++ + D D
Sbjct: 338 RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMD 395
Score = 60.5 bits (145), Expect = 2e-09
Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
R R R+R ER+RDRDR+RER+RDR+R+R+R+R+R+ ++ R E+ + + D D+
Sbjct: 340 RYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK- 398
Query: 244 GP 245
GP
Sbjct: 399 GP 400
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 159 GDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDR 218
GD P + ++ + R R RDR ER R+RDR+RER+RDR+R+ +++R
Sbjct: 323 GDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
Query: 219 DRDRDRDRDRERDRDR 234
++ + D D D+
Sbjct: 383 YFEKPKVDDEPMDVDK 398
Score = 45.8 bits (107), Expect = 6e-05
Identities = 21/50 (42%), Positives = 31/50 (62%)
Query: 216 RDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLY 265
RD++R+R R+R+R+R+RDR+RDR+R+RE R R K Y
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSY 383
Score = 31.6 bits (70), Expect = 1.2
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRD-----RDRDRERDRD-RDRDRDRDRE 229
A +SA P +SR + E N D D R + + R ++ ER+R+ ++ RDR +E
Sbjct: 46 APTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKE 105
Query: 230 R 230
R
Sbjct: 106 R 106
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 73.2 bits (178), Expect = 4e-13
Identities = 38/75 (50%), Positives = 52/75 (69%), Gaps = 3/75 (4%)
Query: 184 RSRSRDRSHERNR--DRDRDRERDRDRDRDRDRERDRDR-DRDRDRDRERDRDRERDRDR 240
+ R ++ ERNR +R++ RE R+RDR+R+RER+RDR DRDRDR+R+R+R RERDR
Sbjct: 1261 KEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRD 1320
Query: 241 DREGPFRRSDSFPER 255
+ RS S P R
Sbjct: 1321 TKRHSRSRSRSTPVR 1335
Score = 72.0 bits (175), Expect = 8e-13
Identities = 35/78 (44%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDR-DRERDRDRDRDRDRDRE 229
EE+ A R+R +R R R+RDRER+R+R+RDR DR+RDR+RDR+R R+R+
Sbjct: 1258 EEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERD 1317
Query: 230 RDRDRERDRDRDREGPFR 247
R + R R R P R
Sbjct: 1318 RRDTKRHSRSRSRSTPVR 1335
Score = 70.5 bits (171), Expect = 2e-12
Identities = 55/216 (25%), Positives = 100/216 (46%), Gaps = 7/216 (3%)
Query: 32 LKKQSSSSTTSQGGVKRSLSEQPVMDTATATE-QAKQLVKSGAISAIKAETKNSGFKRSR 90
L + S + T + G+ R L P +A+Q + A+ AE + +R R
Sbjct: 1099 LVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRER 1158
Query: 91 TLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDG 150
T + D +K P RS S D +E ++ ++KS + + L
Sbjct: 1159 TRSEREWDRDK---VREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLF 1215
Query: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210
+ + P + ++ + A R +++ E ++R+++ ER+R+R
Sbjct: 1216 RKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQL 1275
Query: 211 DRDRERDRDRDRDRDRDRERDR---DRERDRDRDRE 243
+R++ R+ R+RDR+R+RER+R DR+RDR+RDRE
Sbjct: 1276 EREKRREHSRERDRERERERERDRGDRDRDRERDRE 1311
Score = 53.1 bits (126), Expect = 4e-07
Identities = 30/58 (51%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 181 SPPRSRSRDRSHERNR-DRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE-RDRDRER 236
S R R R+R ER+R DRDRDRERDR+R R+RDR + R R R RDR R
Sbjct: 1284 SRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 97 KDPEKGPVPTFQPFQRS-ISADDDLQ-ESSRRPQRKSLYESFVSSSDRLRE---LGPDGE 151
K PE+ +P Q + SA DL+ ES R Q L ++ + + E P E
Sbjct: 494 KVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLE 553
Query: 152 EAEGPGAGDG--PPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRD 209
+ EG A P + S SS+S SRSR RS + + R R + RD
Sbjct: 554 QKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRD 613
Query: 210 RDRDRERDRDRDRDRDRDRERDRDRERDRDRDR 242
+ R R R + R R R R R R
Sbjct: 614 VAQARTHANPRGRPKMGSRSTSESRSRSRSRSR 646
Score = 33.1 bits (74), Expect = 0.43
Identities = 24/88 (27%), Positives = 31/88 (35%), Gaps = 8/88 (9%)
Query: 174 SGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRD 233
S S SP RS+ RD + R R R + R R R R R R + +
Sbjct: 598 SSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLS 657
Query: 234 RERDRDRDREGPFRRSDSFPERRAPRKG 261
RD S S+ E + P G
Sbjct: 658 PGVSRD--------SSTSYTETKDPSSG 677
Score = 29.6 bits (65), Expect = 4.7
Identities = 23/83 (27%), Positives = 28/83 (33%), Gaps = 12/83 (14%)
Query: 179 SASPPRSRSRDRSHERNRDRDRD------------RERDRDRDRDRDRERDRDRDRDRDR 226
SA SRS S +R R R R + RD + R R R + R
Sbjct: 573 SADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSR 632
Query: 227 DRERDRDRERDRDRDREGPFRRS 249
R R R R R R+S
Sbjct: 633 STSESRSRSRSRSRSASSNSRKS 655
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 72.4 bits (176), Expect = 6e-13
Identities = 45/119 (37%), Positives = 66/119 (55%), Gaps = 20/119 (16%)
Query: 161 GPPRSFDWGYEERSGAHSSASPPRSRSRD-RSHERNRDRDRDRERDRDRDRDRDRERDRD 219
G +F Y E H+ R R R+ R ER R+R+RDRER+R R R+R+RER+ +
Sbjct: 383 GQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERER-RQREREREREHE 441
Query: 220 RDRDRDRDRE----------------RDRDRERDRDRDREGPFRRSDSFPERRA--PRK 260
RD++R R +E RDRDRE++R++++ P RS P R+A P+K
Sbjct: 442 RDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKK 500
Score = 31.6 bits (70), Expect = 1.2
Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 109 PFQRSISADDDLQES---SRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRS 165
P++RS S L S SR +R+ S S+S+ R + G G+ RS
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYS-GSGSSRSRSRS 576
Query: 166 FDWG-YEERSGAHSSASPPRSRSRDRS 191
+ Y RS HSS S RSRSR S
Sbjct: 577 SSYSSYSSRSSRHSSFSGSRSRSRSFS 603
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 72.0 bits (175), Expect = 8e-13
Identities = 37/73 (50%), Positives = 49/73 (67%), Gaps = 4/73 (5%)
Query: 169 GYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDR 228
G E +S S R RSR+R H R+R++ R R + R RDR D R+R R+R+R RDR
Sbjct: 479 GIESKSYGSGSR---RERSRERDHSRSREKSR-RHKSRSRDRHDDYYRERSRERERHRDR 534
Query: 229 ERDRDRERDRDRD 241
+RDRDRERDR+R+
Sbjct: 535 DRDRDRERDRERE 547
Score = 63.5 bits (153), Expect = 3e-10
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 134 ESFVSSSDRLRELGPD------GEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRS 187
+S VS+ DR + L G E++ G+G RS + + S + + +SRS
Sbjct: 457 QSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRE---RDHSRSREKSRRHKSRS 513
Query: 188 RDRSHERNRDRDRDRERDRDRDRDRDRERDRDRD 221
RDR + R+R R+RER RDRDRDRDRERDR+R+
Sbjct: 514 RDRHDDYYRERSRERERHRDRDRDRDRERDRERE 547
Score = 57.4 bits (137), Expect = 2e-08
Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREG 244
S+S R R R+RD R R++ R R + R RDR D R+R R+R+R RDRDRDR+
Sbjct: 482 SKSYGSGSRRERSRERDHSRSREKSR-RHKSRSRDRHDDYYRERSRERERHRDRDRDRDR 540
Query: 245 PFRRSDSFPER 255
R + R
Sbjct: 541 ERDREREYRHR 551
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 72.0 bits (175), Expect = 8e-13
Identities = 47/94 (50%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 173 RSGAHSSASPP---RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
RSG+ S + P RS+ D R+RDRDR RER R RD+ R R RDR R R R R RE
Sbjct: 17 RSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLR-RSRSRE 75
Query: 230 RDRDRERDRDRDREGPFRRSDSFPER-RAPRKGN 262
RDR RER R R R+ RS S R R+ GN
Sbjct: 76 RDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGN 109
Score = 68.2 bits (165), Expect = 1e-11
Identities = 45/92 (48%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 169 GYEERSGAHSSASPPRS--RSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDR 226
G E R SAS RS RSR RS R + D R R RDRDR RER R RD+ R R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 227 DRERDR-DRERDRDRDREGPFRRSDSFPERRA 257
R+R R R R R+RDR RRS S RR+
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRS 93
Score = 62.8 bits (151), Expect = 5e-10
Identities = 37/85 (43%), Positives = 43/85 (50%)
Query: 175 GAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
G S RS SR RS R+R R +R + D R R RDRDR R+R R R++ R R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 235 ERDRDRDREGPFRRSDSFPERRAPR 259
RDR R R R D ERR R
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSR 86
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/72 (41%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 184 RSRSRDRSHERNRDR-----DRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDR 238
RSRSRD+ R+RDR R RERDR R+R R R RDR R R R R R ++
Sbjct: 51 RSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK 110
Query: 239 DRDREGPFRRSD 250
+ E R +
Sbjct: 111 SKKTENRSRSKE 122
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 11/84 (13%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDR-----------DRERDRDRDRDRDRDRERDR 232
RSR RDRS ER R R RDR R R R R R + +R R +++ E +
Sbjct: 72 RSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSK 131
Query: 233 DRERDRDRDREGPFRRSDSFPERR 256
++++D+D + + + +F + +
Sbjct: 132 EKKKDKDDKEDEKEKDAGNFDQNK 155
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 71.6 bits (174), Expect = 1e-12
Identities = 32/53 (60%), Positives = 41/53 (77%)
Query: 196 RDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
R R R+R+R+R+RDR RD RDR+RDR RDR+RER+R +RDRDR G +RR
Sbjct: 657 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 709
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/52 (67%), Positives = 39/52 (75%), Gaps = 1/52 (1%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDR-ERDRDR 234
RSR R+R ER RDR RD RDR+RDR RDRER+R+R DRDRDR ER R R
Sbjct: 657 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 708
Score = 63.5 bits (153), Expect = 3e-10
Identities = 33/56 (58%), Positives = 41/56 (73%), Gaps = 1/56 (1%)
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
S R R ER+R+R+RDR RD RDR+RDR RDR+R+R+R DR+RDR ER R R
Sbjct: 654 SGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYR 708
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 6/191 (3%)
Query: 59 ATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADD 118
+T T++ K V S + + + S KR + +GK K + + AD
Sbjct: 54 STDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADR 113
Query: 119 DLQESS---RRPQRKSLYESFVSSSD---RLRELGPDGEEAEGPGAGDGPPRSFDWGYEE 172
++ SS R P + ++ V D R + PDG E G RS EE
Sbjct: 114 KIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE 173
Query: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDR 232
+ + S + N + + + D + D + E D + D + D D E +
Sbjct: 174 VNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEE 233
Query: 233 DRERDRDRDRE 243
+ E + + + E
Sbjct: 234 EEEEEEEEEEE 244
Score = 30.4 bits (67), Expect = 2.8
Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 163 PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNR--DRDRDR-ERDRDR 208
PR D E + R R RDR ER R DRDRDR ER R R
Sbjct: 660 PRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 708
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 71.6 bits (174), Expect = 1e-12
Identities = 32/53 (60%), Positives = 41/53 (77%)
Query: 196 RDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
R R R+R+R+R+RDR RD RDR+RDR RDR+RER+R +RDRDR G +RR
Sbjct: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/52 (67%), Positives = 39/52 (75%), Gaps = 1/52 (1%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDR-ERDRDR 234
RSR R+R ER RDR RD RDR+RDR RDRER+R+R DRDRDR ER R R
Sbjct: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
Score = 63.5 bits (153), Expect = 3e-10
Identities = 33/56 (58%), Positives = 41/56 (73%), Gaps = 1/56 (1%)
Query: 185 SRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
S R R ER+R+R+RDR RD RDR+RDR RDR+R+R+R DR+RDR ER R R
Sbjct: 672 SGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYR 726
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 6/191 (3%)
Query: 59 ATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADD 118
+T T++ K V S + + + S KR + +GK K + + AD
Sbjct: 54 STDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADR 113
Query: 119 DLQESS---RRPQRKSLYESFVSSSD---RLRELGPDGEEAEGPGAGDGPPRSFDWGYEE 172
++ SS R P + ++ V D R + PDG E G RS EE
Sbjct: 114 KIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE 173
Query: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDR 232
+ + S + N + + + D + D + E D + D + D D E +
Sbjct: 174 VNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEE 233
Query: 233 DRERDRDRDRE 243
+ E + + + E
Sbjct: 234 EEEEEEEEEEE 244
Score = 30.4 bits (67), Expect = 2.8
Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 163 PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNR--DRDRDR-ERDRDR 208
PR D E + R R RDR ER R DRDRDR ER R R
Sbjct: 678 PRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 71.2 bits (173), Expect = 1e-12
Identities = 68/215 (31%), Positives = 93/215 (43%), Gaps = 23/215 (10%)
Query: 60 TATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDD 119
T+ ++ K+ +S + +A + RSR+ E K K +G + RS S +
Sbjct: 16 TSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR----KHRSRSRSKEGR 71
Query: 120 LQESSRRPQRKSLYESFVS---SSDRLREL------GPDGEEAEGPGAGDGPPRSFDWGY 170
ES + +K E SSD+ RE G D + + + G S
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
Query: 171 EERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRER-----DRDRDRDRD 225
E R H S S R +SR RS ER + R R RER + R R R+R+R R R R R
Sbjct: 132 ERR---HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188
Query: 226 RDRERDRDRERDRDRDR--EGPFRRSDSFPERRAP 258
R R R R R R RDR + E P R S S +P
Sbjct: 189 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
Score = 43.5 bits (101), Expect = 3e-04
Identities = 53/227 (23%), Positives = 88/227 (38%), Gaps = 8/227 (3%)
Query: 23 KKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAISAIKAETK 82
KKK+++ +++ ++S S RS S + E K +S + + E+K
Sbjct: 22 KKKEQSEVSVSPRASKHHYS-----RSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
Query: 83 NSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDR 142
+ K+ ++ E D E + S + +D + R+ R + S R
Sbjct: 77 DKSSKKHKSEEHN--DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
Query: 143 LRELGPDGEEAEGPGAGDGPPRSFDWGYEE-RSGAHSSASPPRSRSRDRSHERNRDRDRD 201
R + +++ RS ++ RS + RSRSR RS R+R R R
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS 194
Query: 202 RERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
R R R RDR + E+ R R R R R+ D + R
Sbjct: 195 RTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 172 ERSG-AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRER 230
ER G A SP R + +++S R R R R R+R+R D + + R R R
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 231 DRDRERDRDRDREGPFRRSDSFPER 255
++ R +D+ +S+ ++
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDK 91
Score = 29.3 bits (64), Expect = 6.1
Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 13/109 (11%)
Query: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRE--------RDRDRDRDRDRDRERDRDRE 235
R+RSR R+ R+RDR + E+ R R R R+ D R +R ++
Sbjct: 189 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 248
Query: 236 RDRDRDREGPFRRSDSFPERRAPRKGNTLYV-----YGEDMTPTLLRGA 279
R++E ++ A G+ L V G +TP + A
Sbjct: 249 LQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAA 297
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 70.1 bits (170), Expect = 3e-12
Identities = 43/94 (45%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 170 YEERSGAHSSASPPRSRSRDRSHER---NRDRDRDRERDRDRDRDRDRERDRDRDRDRDR 226
Y+ER G S P R R RDR ER +R+RD++RER R R RDR R R R RD++
Sbjct: 219 YDERPGP--SPLPHRDRDRDRERERRERSRERDKERERRRSRSRDR-RRRSRSRDKE--- 272
Query: 227 DRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
+R R R+R +D+DRDR+ RS R RK
Sbjct: 273 ERRRSRERSKDKDRDRKRRSSRSRERARRERERK 306
Score = 64.3 bits (155), Expect = 2e-10
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 87 KRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLREL 146
+RSR+ + + + + + +RS D D + S R + ++ E +R EL
Sbjct: 255 RRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRER-----ERKEEL 309
Query: 147 -GPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERD 205
G G+ AE AGD PP G G R R R+R +R+R R+RD
Sbjct: 310 RGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRD 369
Query: 206 RDRDRDRDRER-DRDRDRDRDRDR 228
RDRDRDR+ +R +R +R RD R
Sbjct: 370 RDRDRDREHKRGERGSERGRDEAR 393
Score = 58.9 bits (141), Expect = 7e-09
Identities = 44/135 (32%), Positives = 56/135 (41%), Gaps = 51/135 (37%)
Query: 172 ERSGAHSSASPPRSRSRD-----RSHERNRDRDRDRERDRDRDRDRDRE----------- 215
ER + S RSRSRD RS ER++D+DRDR+R R R+R R
Sbjct: 253 ERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGG 312
Query: 216 -----------------------------------RDRDRDRDRDRDRERDRDRERDRDR 240
RDRDR+R R ER+R R+RDRDR
Sbjct: 313 GGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDR 372
Query: 241 DREGPFRRSDSFPER 255
DR+ +R + ER
Sbjct: 373 DRDREHKRGERGSER 387
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/113 (38%), Positives = 53/113 (46%), Gaps = 9/113 (7%)
Query: 154 EGPGAGDGPPRSFDWGYE-ERSGAHSSASPPRSRSRDRSHERNR-DRDRDRE-----RDR 206
E PG P R D E ER R R R RS +R R R RD+E R+R
Sbjct: 221 ERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRER 280
Query: 207 DRDRDRDRERDRDRDRDRDRDRERDRDRE-RDRDRDREGPFRRSDSFPERRAP 258
+D+DRDR+R R R+R R RER+R E R D P D+ P+ P
Sbjct: 281 SKDKDRDRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
Score = 32.3 bits (72), Expect = 0.73
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 23/145 (15%)
Query: 200 RDRERDRD-----RDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPE 254
R+ E RD R R+ +R R R++ R+++ + E P + D+F
Sbjct: 46 REFEDPRDAPPPTRAETREERMERKR-REKIERRQQEVETELKMWDPHNDPNAQGDAF-- 102
Query: 255 RRAPRKGNTLYV--YGEDMTPTLLRGAFSPFGNIIDLSM------DPPRNCAFVTYEKME 306
TL+V D T + LR F +G I + M PR AF+ YE
Sbjct: 103 -------KTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHER 155
Query: 307 SADQAVAELNGTQVESVQLKVNIAR 331
A +G +++ ++ V++ R
Sbjct: 156 DMHSAYKHADGKKIDGRRVLVDVER 180
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/264 (26%), Positives = 108/264 (40%), Gaps = 28/264 (10%)
Query: 7 GLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAK 66
G EE + + K +LK++++ L + ++S+ S ++ + V A+
Sbjct: 150 GKVEEAQGMMKLVEQLKEERELL----RSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQ 205
Query: 67 QLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRR 126
V + ++ G+ + + +LK EK T +P + + + R
Sbjct: 206 SRVDDHLMGK-----QHMGYAKIKATVEELK--EKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 127 PQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSR 186
+R+ E +R R+ + EE E A D ER S S SR
Sbjct: 259 KERERERE------ERERKRRREEEEREKERARD----------RERRKRSRSRSRHSSR 302
Query: 187 SRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPF 246
+ DR R+RD R R R+R R R RDR R R DR + R R RDR R + RDR+
Sbjct: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362
Query: 247 RRSDSFPERRAPRKGNTLYVYGED 270
RS S +R RK G D
Sbjct: 363 HRSKS-RDREQDRKSKEKEKRGSD 385
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 184 RSRSRDRSHE----RNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRD 239
RSRS DRS R+RDR R + RDR + R + RDR++DR +R D ++
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 240 RDREGPFRRSDSFPERRAPRKGNTLYVYGEDM 271
+ + D+ E + N + ED+
Sbjct: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/80 (27%), Positives = 34/80 (42%)
Query: 164 RSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRD 223
RS ER S RS+SRDR ++R + RDRE+DR R D +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 224 RDRDRERDRDRERDRDRDRE 243
+ RE+ + ++ +
Sbjct: 392 KSGSREKQSEDTNTESKESD 411
Score = 37.0 bits (84), Expect = 0.029
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 7/98 (7%)
Query: 173 RSGAHS-SASPPRSRSRDRSHERNRDR------DRDRERDRDRDRDRDRERDRDRDRDRD 225
RS +H S RSRSRDR ++RDR + R+R++DR +R D +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 226 RDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
+ R++ E +E + + +G+T
Sbjct: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDT 429
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/264 (26%), Positives = 108/264 (40%), Gaps = 28/264 (10%)
Query: 7 GLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAK 66
G EE + + K +LK++++ L + ++S+ S ++ + V A+
Sbjct: 150 GKVEEAQGMMKLVEQLKEERELL----RSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQ 205
Query: 67 QLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRR 126
V + ++ G+ + + +LK EK T +P + + + R
Sbjct: 206 SRVDDHLMGK-----QHMGYAKIKATVEELK--EKLRKRTEEPDRDERLKKEKQEREERE 258
Query: 127 PQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSR 186
+R+ E +R R+ + EE E A D ER S S SR
Sbjct: 259 KERERERE------ERERKRRREEEEREKERARD----------RERRKRSRSRSRHSSR 302
Query: 187 SRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPF 246
+ DR R+RD R R R+R R R RDR R R DR + R R RDR R + RDR+
Sbjct: 303 TSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYK 362
Query: 247 RRSDSFPERRAPRKGNTLYVYGED 270
RS S +R RK G D
Sbjct: 363 HRSKS-RDREQDRKSKEKEKRGSD 385
Score = 44.7 bits (104), Expect = 1e-04
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 184 RSRSRDRSHE----RNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRD 239
RSRS DRS R+RDR R + RDR + R + RDR++DR +R D ++
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 240 RDREGPFRRSDSFPERRAPRKGNTLYVYGEDM 271
+ + D+ E + N + ED+
Sbjct: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDI 423
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/80 (27%), Positives = 34/80 (42%)
Query: 164 RSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRD 223
RS ER S RS+SRDR ++R + RDRE+DR R D +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 224 RDRDRERDRDRERDRDRDRE 243
+ RE+ + ++ +
Sbjct: 392 KSGSREKQSEDTNTESKESD 411
Score = 37.0 bits (84), Expect = 0.029
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 7/98 (7%)
Query: 173 RSGAHS-SASPPRSRSRDRSHERNRDR------DRDRERDRDRDRDRDRERDRDRDRDRD 225
RS +H S RSRSRDR ++RDR + R+R++DR +R D +
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 226 RDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNT 263
+ R++ E +E + + +G+T
Sbjct: 392 KSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDT 429
>gi|10190682 chromobox homolog 8 [Homo sapiens]
Length = 389
Score = 69.7 bits (169), Expect = 4e-12
Identities = 40/81 (49%), Positives = 51/81 (62%), Gaps = 6/81 (7%)
Query: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDR 240
SPP S + S R + RDRDRDRDRDRERDR+R+R+R+R+RER+R+RER R
Sbjct: 130 SPPASSTSTSSTCR-----AEAPRDRDRDRDRDRERDRERERERERERERERERERGTSR 184
Query: 241 DREGPFRRSDSFPER-RAPRK 260
+ P DS +R PRK
Sbjct: 185 VDDKPSSPGDSSKKRGPKPRK 205
Score = 64.3 bits (155), Expect = 2e-10
Identities = 39/114 (34%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Query: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERD 237
SS S + + +R+RDRDRDRERDR+R+R+R+RER+R+R+R+R R D+
Sbjct: 134 SSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPG 193
Query: 238 RDRDREGPFRRSD-SFPERR---APRKGNTLYVYGEDMTPTLLRGAFSPFGNII 287
+ GP R + P +R P G Y+ G + T P G+ +
Sbjct: 194 DSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGKFPAGHSV 247
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 68.9 bits (167), Expect = 7e-12
Identities = 26/58 (44%), Positives = 49/58 (84%)
Query: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSD 250
ER R+R+R+RER+ DR+R+++RER+R+++R+++++RER+++RER+ +R RE R +
Sbjct: 236 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 293
Score = 67.8 bits (164), Expect = 2e-11
Identities = 27/73 (36%), Positives = 52/73 (71%)
Query: 170 YEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
+ ER S+ R ER R+R+R+RE DR+R+++R+RER+++R+++++R+RE
Sbjct: 215 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 274
Query: 230 RDRDRERDRDRDR 242
++R+RE +R R++
Sbjct: 275 KERERELERQREQ 287
Score = 67.4 bits (163), Expect = 2e-11
Identities = 24/55 (43%), Positives = 48/55 (87%)
Query: 189 DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
D R R+R+R+RER+R+ DR+R++ER+R+R+++R++++ER+R++ER+R+ +R+
Sbjct: 230 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ 284
Score = 62.4 bits (150), Expect = 7e-10
Identities = 30/86 (34%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Query: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235
+HSS + S D + R+R+R+R+R+RER+ DR+R+++R+RER+++RE
Sbjct: 207 SHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKERE 266
Query: 236 RDRDRDREGPFRRS-DSFPERRAPRK 260
++++R+RE R + E+RA K
Sbjct: 267 QEKEREREKERERELERQREQRAREK 292
Score = 60.5 bits (145), Expect = 2e-09
Identities = 26/76 (34%), Positives = 49/76 (64%)
Query: 201 DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
D E R+R+R+R+RER+R+ DR+R+++RER+R++ER+++++RE R +R R
Sbjct: 230 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 289
Query: 261 GNTLYVYGEDMTPTLL 276
+ + + P+ L
Sbjct: 290 REKELLAAKALEPSFL 305
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 68.9 bits (167), Expect = 7e-12
Identities = 26/58 (44%), Positives = 49/58 (84%)
Query: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSD 250
ER R+R+R+RER+ DR+R+++RER+R+++R+++++RER+++RER+ +R RE R +
Sbjct: 340 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
Score = 67.8 bits (164), Expect = 2e-11
Identities = 27/73 (36%), Positives = 52/73 (71%)
Query: 170 YEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229
+ ER S+ R ER R+R+R+RE DR+R+++R+RER+++R+++++R+RE
Sbjct: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
Query: 230 RDRDRERDRDRDR 242
++R+RE +R R++
Sbjct: 379 KERERELERQREQ 391
Score = 67.4 bits (163), Expect = 2e-11
Identities = 24/55 (43%), Positives = 48/55 (87%)
Query: 189 DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
D R R+R+R+RER+R+ DR+R++ER+R+R+++R++++ER+R++ER+R+ +R+
Sbjct: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ 388
Score = 62.4 bits (150), Expect = 7e-10
Identities = 30/86 (34%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Query: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235
+HSS + S D + R+R+R+R+R+RER+ DR+R+++R+RER+++RE
Sbjct: 311 SHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKERE 370
Query: 236 RDRDRDREGPFRRS-DSFPERRAPRK 260
++++R+RE R + E+RA K
Sbjct: 371 QEKEREREKERERELERQREQRAREK 396
Score = 60.5 bits (145), Expect = 2e-09
Identities = 26/76 (34%), Positives = 49/76 (64%)
Query: 201 DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260
D E R+R+R+R+RER+R+ DR+R+++RER+R++ER+++++RE R +R R
Sbjct: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
Query: 261 GNTLYVYGEDMTPTLL 276
+ + + P+ L
Sbjct: 394 REKELLAAKALEPSFL 409
>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
Length = 1271
Score = 68.9 bits (167), Expect = 7e-12
Identities = 73/269 (27%), Positives = 111/269 (41%), Gaps = 25/269 (9%)
Query: 62 TEQAKQLVKSGAISAIKAETKNSGF---------KRSRTLEGKLKDPEKGPVPTFQPFQR 112
+E+ K+ + + +S + NS F + L +L + ++ T Q Q
Sbjct: 276 SEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQE 335
Query: 113 SISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEE 172
+ S+ ++ E V+ D + D + EG DG + E
Sbjct: 336 GTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQ---DGVEEEV-FEQEA 391
Query: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRD-RDRDRDRERDRDRDRDRDRDRERD 231
+ A S S SRSR RS + R R R R R R R R R R+R R R ER
Sbjct: 392 KKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSER- 450
Query: 232 RDRERDRDRDREG--PFRRSDSFPERRAPRKGNTLYVYGEDMTPTL--LRGAFSPFGNII 287
R RER+++R ++G P R + TL+V D T L F FG I
Sbjct: 451 RAREREKERQKKGLPPIR------SKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIE 504
Query: 288 DLSMDPPRNCAFVTYEKMESADQAVAELN 316
++M PPR CA+V + A +A+ +L+
Sbjct: 505 SINMIPPRGCAYVCMVHRQDAFRALQKLS 533
>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
Length = 410
Score = 68.9 bits (167), Expect = 7e-12
Identities = 47/107 (43%), Positives = 58/107 (54%), Gaps = 19/107 (17%)
Query: 171 EERSGAHSSASPPRSRS--------RDRSHERNRDRDRDRERDRD------RDRDRDRER 216
E+ SGA + PR R + R+H+R RDR D R R RD DRD ER
Sbjct: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
Query: 217 DRDRD--RDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261
D++RD RDR+RDRER+R+RERD DR GP R + RA G
Sbjct: 62 DQERDGNRDRNRDRERERERERDPDR---GPRRDTHRDAGPRAGEHG 105
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/91 (38%), Positives = 51/91 (56%)
Query: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210
E+ G PR D G + PR R D +R+ D +R R+ DRD +R
Sbjct: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
Query: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
D++R+ +RDR+RDR+R+RER+RD +R RD
Sbjct: 62 DQERDGNRDRNRDRERERERERDPDRGPRRD 92
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/72 (37%), Positives = 37/72 (51%)
Query: 156 PGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRE 215
P G R D + R S + R RD ++ RD +RDR RDR+R+R+R+R+
Sbjct: 25 PDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERD 84
Query: 216 RDRDRDRDRDRD 227
DR RD RD
Sbjct: 85 PDRGPRRDTHRD 96
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/84 (30%), Positives = 39/84 (46%)
Query: 142 RLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD 201
R RE P G PR + + + R +R ER+ +RDR+
Sbjct: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
Query: 202 RERDRDRDRDRDRERDRDRDRDRD 225
R+R+R+R+R+RD +R RD RD
Sbjct: 73 RDRERERERERDPDRGPRRDTHRD 96
>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
Length = 401
Score = 68.9 bits (167), Expect = 7e-12
Identities = 47/107 (43%), Positives = 58/107 (54%), Gaps = 19/107 (17%)
Query: 171 EERSGAHSSASPPRSRS--------RDRSHERNRDRDRDRERDRD------RDRDRDRER 216
E+ SGA + PR R + R+H+R RDR D R R RD DRD ER
Sbjct: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
Query: 217 DRDRD--RDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261
D++RD RDR+RDRER+R+RERD DR GP R + RA G
Sbjct: 62 DQERDGNRDRNRDRERERERERDPDR---GPRRDTHRDAGPRAGEHG 105
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/91 (38%), Positives = 51/91 (56%)
Query: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210
E+ G PR D G + PR R D +R+ D +R R+ DRD +R
Sbjct: 2 EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
Query: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
D++R+ +RDR+RDR+R+RER+RD +R RD
Sbjct: 62 DQERDGNRDRNRDRERERERERDPDRGPRRD 92
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/72 (37%), Positives = 37/72 (51%)
Query: 156 PGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRE 215
P G R D + R S + R RD ++ RD +RDR RDR+R+R+R+R+
Sbjct: 25 PDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERD 84
Query: 216 RDRDRDRDRDRD 227
DR RD RD
Sbjct: 85 PDRGPRRDTHRD 96
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/84 (30%), Positives = 39/84 (46%)
Query: 142 RLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD 201
R RE P G PR + + + R +R ER+ +RDR+
Sbjct: 13 RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
Query: 202 RERDRDRDRDRDRERDRDRDRDRD 225
R+R+R+R+R+RD +R RD RD
Sbjct: 73 RDRERERERERDPDRGPRRDTHRD 96
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 68.6 bits (166), Expect = 9e-12
Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 18/152 (11%)
Query: 117 DDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGA 176
D +++E S RK E + + RE D E+A+ G ER A
Sbjct: 170 DAEIKERSTSRDRKQKEE--LKEDRKPREKDKDKEKAKENGGNRHREG-------ERERA 220
Query: 177 HSSASPPRSRSRDRSH-ERNRDRDRDRERDR------DRDRDRDRERDRDRDRDRDRDRE 229
+ A P R +DR + ER+RD +R +E +R +++R RDR+R+RDRD+ +DRDR
Sbjct: 221 KARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRR 280
Query: 230 RDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261
R ++ E D DRE R PE+++ G
Sbjct: 281 RVKNGEHSWDLDREK--NREHDKPEKKSASSG 310
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 13/156 (8%)
Query: 111 QRSISADDDLQES---SRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFD 167
+RS S D +E R+P+ K + + R + E A+ D R D
Sbjct: 175 ERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNE-RQKD 233
Query: 168 WGYEER---------SGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDR 218
G ER + S + R RDR ER+RD+ +DR+R R ++ + + DR
Sbjct: 234 RGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
Query: 219 DRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPE 254
+++R+ D+ ++ + +G F+ S + E
Sbjct: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETE 329
Score = 46.2 bits (108), Expect = 5e-05
Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 23/129 (17%)
Query: 137 VSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGY----EERSGAHSSASP-------PRS 185
+SS D +R + GE+ E G RS + EE S H + RS
Sbjct: 119 LSSDDAVRRVLA-GEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERS 177
Query: 186 RSRDRSHERNRDRDR---DRERDRDRDRDRDRERDRDRDRDR-------DRDRERDR-DR 234
SRDR + DR ++++D+++ ++ R R+ +R+R D +R++DR +R
Sbjct: 178 TSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR 237
Query: 235 ERDRDRDRE 243
ERDRD +R+
Sbjct: 238 ERDRDSERK 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,591,806
Number of Sequences: 37866
Number of extensions: 788850
Number of successful extensions: 16743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 334
Number of HSP's that attempted gapping in prelim test: 5366
Number of HSP's gapped (non-prelim): 3598
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.