Search of human proteins with 14602443

Search of human proteins with 14602443

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
         (1019 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]      2014   0.0  
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]     1970   0.0  
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]     1970   0.0  
gi|38505161 tudor domain containing 1 [Homo sapiens]                   57   7e-08
gi|30039692 NIMA-related kinase 8 [Homo sapiens]                       57   9e-08
gi|58197558 tudor domain containing 6 [Homo sapiens]                   55   4e-07
gi|71061468 centromere protein E [Homo sapiens]                        53   1e-06
gi|4758696 mitogen-activated protein kinase kinase kinase 13 [Ho...    53   1e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    53   2e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             53   2e-06
gi|208431829 eukaryotic translation initiation factor 2-alpha ki...    52   2e-06
gi|208431827 eukaryotic translation initiation factor 2-alpha ki...    52   2e-06
gi|4506103 eukaryotic translation initiation factor 2-alpha kina...    52   2e-06
gi|110349799 testis-specific protein kinase 2 [Homo sapiens]           51   5e-06
gi|21735552 mitogen-activated protein kinase kinase kinase 12 [H...    51   6e-06
gi|223671888 interleukin-1 receptor-associated kinase 4 isoform ...    49   2e-05
gi|223671885 interleukin-1 receptor-associated kinase 4 isoform ...    49   2e-05
gi|223671883 interleukin-1 receptor-associated kinase 4 isoform ...    49   2e-05
gi|166795293 interleukin-1 receptor-associated kinase 4 isoform ...    49   2e-05
gi|166795295 interleukin-1 receptor-associated kinase 4 isoform ...    49   2e-05
gi|4758650 kinesin family member 5C [Homo sapiens]                     49   3e-05
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      49   3e-05
gi|66932999 testis-specific protein kinase 1 [Homo sapiens]            48   5e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    47   7e-05
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform...    47   9e-05
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ...    47   9e-05
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ...    47   9e-05
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]              47   9e-05
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]               47   9e-05
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       46   2e-04

>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
          Length = 1019

 Score = 2014 bits (5219), Expect = 0.0
 Identities = 1019/1019 (100%), Positives = 1019/1019 (100%)

Query: 1    MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMK 60
            MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMK
Sbjct: 1    MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMK 60

Query: 61   IGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTE 120
            IGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTE
Sbjct: 61   IGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTE 120

Query: 121  ILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIK 180
            ILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIK
Sbjct: 121  ILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIK 180

Query: 181  ATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPI 240
            ATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPI
Sbjct: 181  ATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPI 240

Query: 241  PLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKI 300
            PLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKI
Sbjct: 241  PLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKI 300

Query: 301  KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI 360
            KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI
Sbjct: 301  KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI 360

Query: 361  DTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL 420
            DTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL
Sbjct: 361  DTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL 420

Query: 421  AQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEA 480
            AQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEA
Sbjct: 421  AQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEA 480

Query: 481  VYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEG 540
            VYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEG
Sbjct: 481  VYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEG 540

Query: 541  SLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIA 600
            SLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIA
Sbjct: 541  SLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIA 600

Query: 601  TVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPD 660
            TVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPD
Sbjct: 601  TVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPD 660

Query: 661  GSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGG 720
            GSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGG
Sbjct: 661  GSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGG 720

Query: 721  LLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRA 780
            LLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRA
Sbjct: 721  LLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRA 780

Query: 781  WREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQ 840
            WREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQ
Sbjct: 781  WREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQ 840

Query: 841  GLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELK 900
            GLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELK
Sbjct: 841  GLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELK 900

Query: 901  MGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSS 960
            MGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSS
Sbjct: 901  MGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSS 960

Query: 961  MTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 1019
            MTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC
Sbjct: 961  MTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 1019


>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 1970 bits (5104), Expect = 0.0
 Identities = 996/996 (100%), Positives = 996/996 (100%)

Query: 24   MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 83
            MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK
Sbjct: 1    MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60

Query: 84   IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY 143
            IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY
Sbjct: 61   IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY 120

Query: 144  KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV 203
            KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV
Sbjct: 121  KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV 180

Query: 204  LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM 263
            LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM
Sbjct: 181  LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM 240

Query: 264  TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES 323
            TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES
Sbjct: 241  TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES 300

Query: 324  YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS 383
            YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS
Sbjct: 301  YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS 360

Query: 384  VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE 443
            VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE
Sbjct: 361  VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE 420

Query: 444  MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC 503
            MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC
Sbjct: 421  MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC 480

Query: 504  DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC 563
            DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC
Sbjct: 481  DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC 540

Query: 564  KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS 623
            KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS
Sbjct: 541  KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS 600

Query: 624  PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 683
            PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY
Sbjct: 601  PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 660

Query: 684  HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR 743
            HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR
Sbjct: 661  HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR 720

Query: 744  PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP 803
            PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP
Sbjct: 721  PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP 780

Query: 804  MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 863
            MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL
Sbjct: 781  MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 840

Query: 864  NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV 923
            NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV
Sbjct: 841  NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV 900

Query: 924  QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP 983
            QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP
Sbjct: 901  QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP 960

Query: 984  EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 1019
            EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC
Sbjct: 961  EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 996


>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 1970 bits (5104), Expect = 0.0
 Identities = 996/996 (100%), Positives = 996/996 (100%)

Query: 24   MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 83
            MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK
Sbjct: 1    MDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNK 60

Query: 84   IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY 143
            IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY
Sbjct: 61   IYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKY 120

Query: 144  KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV 203
            KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV
Sbjct: 121  KLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEV 180

Query: 204  LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM 263
            LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM
Sbjct: 181  LKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKM 240

Query: 264  TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES 323
            TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES
Sbjct: 241  TLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLES 300

Query: 324  YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS 383
            YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS
Sbjct: 301  YKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDIS 360

Query: 384  VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE 443
            VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE
Sbjct: 361  VRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNE 420

Query: 444  MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC 503
            MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC
Sbjct: 421  MQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKC 480

Query: 504  DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC 563
            DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC
Sbjct: 481  DKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVC 540

Query: 564  KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS 623
            KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS
Sbjct: 541  KELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKS 600

Query: 624  PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 683
            PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY
Sbjct: 601  PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 660

Query: 684  HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR 743
            HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR
Sbjct: 661  HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKR 720

Query: 744  PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP 803
            PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP
Sbjct: 721  PLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDP 780

Query: 804  MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 863
            MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL
Sbjct: 781  MAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 840

Query: 864  NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV 923
            NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV
Sbjct: 841  NREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSV 900

Query: 924  QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP 983
            QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP
Sbjct: 901  QNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNP 960

Query: 984  EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 1019
            EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC
Sbjct: 961  EKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC 996


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 54/179 (30%), Positives = 83/179 (46%), Gaps = 10/179 (5%)

Query: 37  VGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDP--NKIYGGLFSEDQC 94
           V +HI+    F+ Q +   + + ++  SLS+ C Q      +  P    I    FSED  
Sbjct: 499 VVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPP-RSDFYPAIGDICCAQFSEDDQ 557

Query: 95  WYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE-IPLELQFSSVAKKYKLWGLHIPSD 153
           WYR  VL   S E  LV Y+DYGN EIL+   +   IP  L+    A K  L G+  PS 
Sbjct: 558 WYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVK-PSL 616

Query: 154 QEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGT---VIAQAEYGSVDIGEEVLKKGFA 209
              T   +    +  L+  K I +++    E+ +   +I ++E   V + + +L  GFA
Sbjct: 617 GIWT--PEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFA 673



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 17/141 (12%)

Query: 31  DKVEDVVGSHIEDAVTFWAQSINRN--KDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGL 88
           D+  DVV   I     F+   +  +  K +  +  SL+E C Q        +  +     
Sbjct: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772

Query: 89  FSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI-------VEIP---LELQFSS 138
           F+ D  WYR  V +I+      V ++DYGN E +   ++       + +P   +  Q + 
Sbjct: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832

Query: 139 VAKKYKLWGLHIPSDQEVTQF 159
           +  + K W     S++ +T+F
Sbjct: 833 IQSRNKHW-----SEEAITRF 848



 Score = 30.4 bits (67), Expect = 8.9
 Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 89  FSEDQCWYRCKVLKI-ISVEKCLVRYIDYGNTEIL 122
           ++ DQ W R  +  + +  +K  V YIDYGN EI+
Sbjct: 323 YTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEII 357


>gi|30039692 NIMA-related kinase 8 [Homo sapiens]
          Length = 692

 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 3/111 (2%)

Query: 821 QANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIV--GDFDFTKS 878
           + N  L  E  L     +   LH +H   I+H  L   N+  L++ + +V  GDF  +K 
Sbjct: 95  RCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNIL-LDKHRMVVKIGDFGISKI 153

Query: 879 VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSVQNQEFE 929
           +S ++    +VG    +SPEL  GKP +  SD++A GC+L  L+   + FE
Sbjct: 154 LSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFE 204


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 65/231 (28%), Positives = 99/231 (42%), Gaps = 37/231 (16%)

Query: 15   SVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIM-KIGCSLSEVCPQAS 73
            SV          D      E V  +HI+D  TF+ Q + RN +I+ ++ CS++    Q S
Sbjct: 969  SVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFYCQ-LARNANILEQLSCSIT----QLS 1023

Query: 74   SVLGNLDPNKIYGGLFS----EDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVE 129
             VL NL  + +  G        D  WYR  V   I  E   V ++D+GN  ++   D++ 
Sbjct: 1024 KVLLNLKTSPLNPGTLCLAKYTDGNWYRGIV---IEKEPKKVFFVDFGNIYVVTSDDLLP 1080

Query: 130  IP------LELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATS 183
            IP      L L   +V         HIP  +EV  + Q T      I +K +K  + A  
Sbjct: 1081 IPSDAYDVLLLPMQAVRCSLSDIPDHIP--EEVVVWFQET------ILDKSLKALVVAKD 1132

Query: 184  EDGTVIAQAEYGSVDIGEEVLKK----GFAEKCR------LASRTDICEEK 224
             DGT+I +    ++ I   + KK     + ++ R      L S T+  EEK
Sbjct: 1133 PDGTLIIELYGDNIQISASINKKLGLLSYKDRIRKKESEVLCSTTETLEEK 1183



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 39   SHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGN-LDPNKIYGGLFSEDQCWYR 97
            SHI D   F+ Q I    +I  +   L+ V  +    +G  L    +   +F ED  WYR
Sbjct: 1312 SHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPLQRGDMICAVFPEDNLWYR 1371

Query: 98   CKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPL 132
              + +    +   V++IDYGN  +++ + I  + L
Sbjct: 1372 AVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDL 1406



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 13/128 (10%)

Query: 39  SHIEDAVTFWAQSINRNKDIMKIGCSLSEVC-----PQASSVLGNLDPNKIYGGLFSEDQ 93
           S++E+   FW Q     + +  +   +   C     P   + L  L    +       ++
Sbjct: 779 SYVENPGYFWCQLTRNIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTV-------NR 831

Query: 94  CWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLE-LQFSSVAKKYKLWGLHIPS 152
            W R  +  I SVE   V ++DYG+ E+++  +I  I  E L+  + A +  L+ L  P 
Sbjct: 832 QWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPV 891

Query: 153 DQEVTQFD 160
            Q    +D
Sbjct: 892 GQNPFVWD 899


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 89/447 (19%), Positives = 197/447 (44%), Gaps = 40/447 (8%)

Query: 266  DLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKT---EKDALLE 322
            ++ +  +  N +    E     D    + + +E+++ ++K  E  E++K+   E+D L  
Sbjct: 1297 EVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKT 1356

Query: 323  SYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLK-TYIDTRMKNLAAKMEILKEMRHVD 381
              +ALE+K +Q+ + +++  A   +  +  E +L     D     + ++ME  K      
Sbjct: 1357 IKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSAL 1416

Query: 382  ISVRFGK-DLSDAIQVLDEGCFTTPASLNGL----EIIWAEYSLAQENIK--------TC 428
            + +      LS  +Q   +   +     + L    E++ +E    +ENIK        T 
Sbjct: 1417 LRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETE 1476

Query: 429  EYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQD-LSVSLEAVYGQAKE 487
            E +   +  + ++ E   +L +++ +   E + S++ K+L+ + D L   ++ +Y + +E
Sbjct: 1477 EELKVAHCCLKEQEETINELRVNLSE--KETEISTIQKQLEAINDKLQNKIQEIY-EKEE 1533

Query: 488  GANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDA 547
              N  +I +     K ++ ++F   R   D++L  + +      K+ +L+       +++
Sbjct: 1534 QFNIKQISE--VQEKVNELKQFKEHRKAKDSALQSIES------KMLELTNR----LQES 1581

Query: 548  MDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYK 607
             + I  ++++ E    K ++ AL  + D  KE   NT   V +   S+E+    ++    
Sbjct: 1582 QEEIQIMIKEKEE--MKRVQEALQIERDQLKE---NTKEIVAKMKESQEKEYQFLKMTAV 1636

Query: 608  DSIEFKKQLIEYLNKSPSVD--HLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIE 665
            +  + K   IE+L +       +L +I+     L  +L   L E  ++ +  D   S  E
Sbjct: 1637 NETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEE 1696

Query: 666  KIKEEITQLRNNVFQEIYHEREEYEML 692
             +K E  QL+ N+ + I  + E+ E L
Sbjct: 1697 TLKVERDQLKENLRETITRDLEKQEEL 1723



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 88/444 (19%), Positives = 174/444 (39%), Gaps = 57/444 (12%)

Query: 295  VSLEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEY 354
            V+L+  ++   L  EN +LK +   L  +YK +E  ++    +L+ +K   VDL   L+ 
Sbjct: 633  VALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQS 692

Query: 355  T------LKTYIDTRM-KNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPAS 407
                   L + ID ++ K+L   +E+  E +  D+     K++ +   + +E    +   
Sbjct: 693  AFNEITKLTSLIDGKVPKDLLCNLEL--EGKITDLQKELNKEVEENEALREEVILLSELK 750

Query: 408  LNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDE------ 461
                E+      +  ++ +     SE + L ++    + ++   +E+     D+      
Sbjct: 751  SLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQS 810

Query: 462  --SSLNKRLKTLQDLSVSLEAVY---------------GQAKEGANSDE---ILKKFYDW 501
               S ++  +  + L +  E  Y                 +KE    D     LK    +
Sbjct: 811  NYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSY 870

Query: 502  KCDKREEFTSVRSETDASLHRLVAWFQ-RTLKVFDLSVEGSLISEDAMDNIDEILEKT-E 559
            K  + +E T    E    + +L    + R   +  +  E +LI+E     ++E+   T E
Sbjct: 871  KTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE 930

Query: 560  SSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEY 619
                K+L+ +L  + D           Q+   IH    +    Q + ++++E  KQ  E 
Sbjct: 931  KDDLKQLQESLQIERD-----------QLKSDIHDTVNMNIDTQEQLRNALESLKQHQET 979

Query: 620  LNK-----SPSVDHLLSIKKTLKSLKALLRWKLV---EKSNLEESDDPDGSQIEKIKEEI 671
            +N      S  V   L +++     K   + K+V   +K +LE  +    +   K  E I
Sbjct: 980  INTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEII 1039

Query: 672  TQLRNNVFQEIYHEREEYEMLTSL 695
             Q R  +F  I  + E  +ML S+
Sbjct: 1040 EQQR-KIFSLIQEKNELQQMLESV 1062



 Score = 37.7 bits (86), Expect = 0.056
 Identities = 124/587 (21%), Positives = 236/587 (40%), Gaps = 89/587 (15%)

Query: 246  RSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEK-IKQDQ 304
            +  Q T  + +G +SEK       + D  N     +E +     N    ++L+K + + Q
Sbjct: 1784 KEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQ 1843

Query: 305  KLIEENEKLKTE-KDALLESYKALELKVEQIAQELQQ--EKAAAV----DLTNHLEYTLK 357
            K + E E+LK + KD  L   K LE++   +AQ+L +  E+  +V    D    +E TLK
Sbjct: 1844 KKVSEMEQLKKQIKDQSLTLSK-LEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902

Query: 358  TYIDTRMKNL----AAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGL-- 411
               D   ++L    A  +EI +E++   +     K+  + +  L E        ++ +  
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARM---LSKEHKETVDKLREKISEKTIQISDIQK 1959

Query: 412  -------EIIWAEYSLAQENIKTCEYVSEGNILIAQRNEMQQ-KLYMSVEDFILE---VD 460
                   E+      L ++ ++      + N+   + NEM+Q K     ++  ++   +D
Sbjct: 1960 DLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMD 2019

Query: 461  ESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRS--ETDA 518
               L K+L        SLE +   AKE    DE+ +     K ++ +   ++R     D 
Sbjct: 2020 NFQLTKKLHE------SLEEIRIVAKE---RDELRRIKESLKMERDQFIATLREMIARDR 2070

Query: 519  SLH------RLVAWFQRTLKVFDLSVEGSLISE-----DAMDNIDEILEKTESSVCKELE 567
              H      RL++  Q+ L    L  + S I E       MD+  E L +    + KE+E
Sbjct: 2071 QNHQVKPEKRLLSDGQQHL-TESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2129

Query: 568  IALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQA--KYKDSIEFKKQLIEYLNKSPS 625
                 Q +    + +N     LQ  H E+   A  +   ++   ++  K ++ Y+ K   
Sbjct: 2130 F----QKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKE 2185

Query: 626  VDHLLSIKKTLKSLKALLRWK--LVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 683
              H    K  +  +  + + K  L++  +L++  D           E+  L+ N   +++
Sbjct: 2186 EQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVP-------SRELRDLKLNQNMDLH 2238

Query: 684  HEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDL---LDAEPMKELS 740
             E    E+L   ++  FP +     ++     +++   +T  LE  L    D E +K   
Sbjct: 2239 IE----EILKDFSESEFPSIKTEFQQV-----LSNRKEMTQFLEEWLNTRFDIEKLKNGI 2289

Query: 741  SKRP----LVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWRE 783
             K       V +  N +II +   S + +      ER+AT  + W +
Sbjct: 2290 QKENDRICQVNNFFNNRIIAIMNESTEFE------ERSATISKEWEQ 2330



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 78/392 (19%), Positives = 164/392 (41%), Gaps = 61/392 (15%)

Query: 304  QKLIEENEKLKTEK----DALLESYKALELKVEQIAQE---LQQEKAAAVDLTNHLEYTL 356
            + +I E E+LKT+     +  +E+ + L L  +++ ++   + QEK  A+     L  T 
Sbjct: 1060 ESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTC 1119

Query: 357  KTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWA 416
                +   K L  K + L+E +   ++V+  +++S+  + ++E        +  L+    
Sbjct: 1120 DRLAEVEEK-LKEKSQQLQEKQQQLLNVQ--EEMSEMQKKINE--------IENLKNELK 1168

Query: 417  EYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSV 476
               L  E+++T            +R E+ QKL  + E+        S+ K  K L++L  
Sbjct: 1169 NKELTLEHMET------------ERLELAQKLNENYEEV------KSITKERKVLKELQK 1210

Query: 477  SLEA----VYGQAKE----GANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQ 528
            S E     + G  +E    G  + E LK  +    + +E    +R        +++    
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD 1270

Query: 529  RTLKVFDLSVEGSLISE--DAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYS 586
                   L  E  ++ E  + + N+ E+ E  E+    ELE+        D   ++    
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQET--MNELELLTEQSTTKDSTTLARIEM 1328

Query: 587  QVL---QKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALL 643
            + L   +K    +  I ++  K +D+++  K+ +E +      +H   I++TL  ++   
Sbjct: 1329 ERLRLNEKFQESQEEIKSL-TKERDNLKTIKEALE-VKHDQLKEH---IRETLAKIQE-S 1382

Query: 644  RWKLVEKSNLEESDDPDGSQIEKIKEEITQLR 675
            + K  +  N++E D    ++  KI  E+ Q +
Sbjct: 1383 QSKQEQSLNMKEKD----NETTKIVSEMEQFK 1410


>gi|4758696 mitogen-activated protein kinase kinase kinase 13 [Homo
           sapiens]
          Length = 966

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 2/129 (1%)

Query: 793 LIFLFLCKSDPMAYLMVPYYPRANLNAV-QANMPLNSEETLKVMKGVAQGLHTLHKADII 851
           + F  +C   P   +++ Y     L  V +A   +     +    G+A G++ LH   II
Sbjct: 217 IAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKII 276

Query: 852 HGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDL 911
           H  L   NV   + +   + DF  +K +S +++     G ++ M+PE+   +P S   D+
Sbjct: 277 HRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 336

Query: 912 YAYGCLLLW 920
           +++G ++LW
Sbjct: 337 WSFG-VVLW 344


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 124/564 (21%), Positives = 226/564 (40%), Gaps = 95/564 (16%)

Query: 259  LSEKMTLDLKDENDAGNLITFPKESLAVGDFN----LGSNVSLE-KIKQDQKLIEENEKL 313
            L EKM   L+++ND    +    E+L   +      + S + LE K+K+  + +EE E++
Sbjct: 877  LEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEM 936

Query: 314  KTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEI 373
             +E   L+   + LE K   + +++       ++LT       K   + ++KNL+ +M  
Sbjct: 937  NSE---LVAKKRNLEDKCSSLKRDIDD-----LELTLTKVEKEKHATENKVKNLSEEMTA 988

Query: 374  LKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSE 433
            L+E  ++    +  K L +A Q   +        +NGL  I A+     +++       E
Sbjct: 989  LEE--NISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDL-------E 1039

Query: 434  GNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDE 493
            G++      E ++KL   +E             + K   DL +S E++     +    +E
Sbjct: 1040 GSL------EQEKKLRADLE-----------RAKRKLEGDLKMSQESIMDLENDKQQIEE 1082

Query: 494  ILKKFYDWKCDKREEFTSVRSETD-ASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNID 552
             LKK       K  E + ++++ D   +H L   FQ+ +K     +E      +A   + 
Sbjct: 1083 KLKK-------KEFELSQLQAKIDDEQVHSLQ--FQKKIKELQARIEELEEEIEAEHTLR 1133

Query: 553  EILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLI--------ATVQA 604
              +EK  S + +ELE    +  +  +E    T +Q+      E            AT+Q 
Sbjct: 1134 AKIEKQRSDLARELE----EISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1189

Query: 605  KYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVE-----------KSNL 653
            +   +   KKQ          +D+L  +K+ L+  K+ L+ ++ +           KSN+
Sbjct: 1190 EATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNI 1249

Query: 654  EESDDPDGSQIEKIK---EEITQLRNNVFQ----------EIYHEREEYEMLTSLAQK-- 698
            E +      Q  +IK   E+ TQL +++            E+ H  EE E L S   K  
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309

Query: 699  -----WFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLVR--SEVN 751
                    EL     E    K   +  L +   + DLL  +  +E  +K  L R  S+ N
Sbjct: 1310 QALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKAN 1369

Query: 752  GQIILLK-GYSVDVDTEAKVIERA 774
             ++   +  Y  D     + +E A
Sbjct: 1370 SEVAQWRTKYETDAIQRTEELEEA 1393



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 78/382 (20%), Positives = 154/382 (40%), Gaps = 41/382 (10%)

Query: 307  IEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKN 366
            +EE E L ++   L +S +AL  ++E++ +++++E  A   + + L+ + +   D   + 
Sbjct: 1295 VEEKESLISQ---LTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS-RHDCDLLREQ 1350

Query: 367  LAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIK 426
               + E   E++         K  S+  Q   +  + T A     E+  A+  LAQ   +
Sbjct: 1351 YEEEQEAKAELQRA-----LSKANSEVAQWRTK--YETDAIQRTEELEEAKKKLAQRLQE 1403

Query: 427  TCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAK 486
              E     N   A   + +Q+L   VED                ++DL  S  A     K
Sbjct: 1404 AEENTETANSKCASLEKTKQRLQGEVEDL---------------MRDLERSHTACATLDK 1448

Query: 487  EGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFD----LSVEGSL 542
            +  N D++L ++     + + E  + + E+ +    L        +V D    L  E   
Sbjct: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKN 1508

Query: 543  ISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERL---- 598
            + E+  D  ++I E  ++    E    LV+Q  +D ++        L+  H E ++    
Sbjct: 1509 LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE--HEESKILRVQ 1566

Query: 599  --IATVQAKYKDSIEFKKQLIEYL--NKSPSVDHLLSI-KKTLKSLKALLRWKLVEKSNL 653
              ++ V+++    +  K + IE L  N   + + L S+    ++S    LR K   + +L
Sbjct: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDL 1626

Query: 654  EESDDPDGSQIEKIKEEITQLR 675
             E +   G    ++ E    LR
Sbjct: 1627 NEMEIQLGHSNRQMAETQKHLR 1648


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 101/456 (22%), Positives = 190/456 (41%), Gaps = 80/456 (17%)

Query: 304  QKLIEENEKLKTEKDALLESYKALELKVEQIAQEL-----------QQEKAAAVDLTNHL 352
            Q  + E +K+K EK+AL+     ++ K+ +++  L           Q+ KAA +DL    
Sbjct: 835  QTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTC 894

Query: 353  EYTLKTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGL- 411
            +  LK  +  +M+N       LKE + +  S+   K+ S  +++           LN + 
Sbjct: 895  K-ELKHQLQVQMEN------TLKEQKELKKSLEKEKEASHQLKL----------ELNSMQ 937

Query: 412  -EIIWAEYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVD-------ESS 463
             ++I A+ +L Q   +  E   +GNI   +++  Q+K  +      L++        E+ 
Sbjct: 938  EQLIQAQNTLKQNEKE--EQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENK 995

Query: 464  LNKRL-KTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHR 522
            L ++L +  Q+L+   E +         S E  K+       +  E  + R +  +   +
Sbjct: 996  LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEK 1055

Query: 523  LVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVCKELEI--ALVDQGDADKEI 580
            L                 SL  ED + N ++I    ++ + +EL+   A ++Q  A KE 
Sbjct: 1056 L-----------------SLAQEDLISNRNQI--GNQNKLIQELKTAKATLEQDSAKKEQ 1096

Query: 581  ISNTYSQVLQKIHSE----ERLIATVQAKYKDSIEFK---KQLIEYLNKSPSVDHLLSIK 633
                  + LQ I  E    E+ +   ++K  +  E K   ++ I  LN+      L SIK
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIK 1156

Query: 634  K--TLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREEYEM 691
            +   LK  K LL   + +K  L+   D   + +E+ K     L++ V      ++EE E+
Sbjct: 1157 EITNLKDAKQLL---IQQKLELQGKADSLKAAVEQEKRNQQILKDQV------KKEEEEL 1207

Query: 692  LTSLAQKWFP-ELPLLHPEIGLLKYMNSGGLLTMSL 726
                 +K       +   E+G+ K+  +   LTM +
Sbjct: 1208 KKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQI 1243



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 88/439 (20%), Positives = 166/439 (37%), Gaps = 89/439 (20%)

Query: 291 LGSNVSLEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTN 350
           L  N++LE+ +       E+EKLK E   L   Y + E  + Q+  EL +          
Sbjct: 236 LMDNMTLERER-------ESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQ 288

Query: 351 HLEYTLKTYIDTRMKNLAAKMEILK--------EMRHVDISVR--------FGKDLSDAI 394
            L+    +  +   KN      +LK        E +H + SV           KDL    
Sbjct: 289 ELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD--C 346

Query: 395 QVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSE--------------------- 433
           Q L      +  SL+ + +  +E   A + +K  E +SE                     
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQKLK--EELSEVETKYQHLKAEFKQLQQQREE 404

Query: 434 ----GNILIAQRNEMQQKLYMSVEDF---------ILEVDESSLNKRLKTLQDLSVSLEA 480
               G  L ++ N++  KL  +               ++    L  + + + DL + L  
Sbjct: 405 KEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSR 464

Query: 481 VYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEG 540
           +  Q KE   +   L+   D    + +E  +++  T A L       ++ L+        
Sbjct: 465 LEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIG----- 519

Query: 541 SLISEDAMDNIDEILEKTESSVC---KELE--IALVDQGDADKEIISNTYSQVLQKIHSE 595
               +  + N++ +L+K++ ++    KE E   A +  G+ +  ++    +Q+ +K H+ 
Sbjct: 520 --DKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVL----NQLQEKNHTL 573

Query: 596 ERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEE 655
           +  +  +  K K+  E  KQ  E L+              ++  KA LR       +LE 
Sbjct: 574 QEQVTQLTEKLKNQSESHKQAQENLHDQ------------VQEQKAHLRAAQDRVLSLET 621

Query: 656 SDDPDGSQIEKIKEEITQL 674
           S +   SQ+ + KE+++QL
Sbjct: 622 SVNELNSQLNESKEKVSQL 640



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 106/529 (20%), Positives = 220/529 (41%), Gaps = 72/529 (13%)

Query: 306  LIEENEKLKTEKDALLESYKALELKVEQIAQELQQEK-------AAAVDLTNHLEYTLKT 358
            L ++ E+L+ +   L      ++   EQ  Q+LQQ++         A +L+  LE   + 
Sbjct: 721  LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780

Query: 359  YIDTRMKNLAAKMEILKEMRHVDISVRFGKD-LSDAIQVLDEGCFTTPASLNGLEIIWAE 417
               TR+ +L  K E L+ ++         K  L    + L +        LN   I    
Sbjct: 781  VSSTRL-DLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN-RIQTTV 838

Query: 418  YSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDES-----SLNKRLKTLQ 472
              L +  ++    ++E + +  + +++   L  S  +F  E  +       L K  K L+
Sbjct: 839  TELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK 898

Query: 473  -DLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTL 531
              L V +E    + KE       LKK  +    ++E    ++ E ++   +L+   Q TL
Sbjct: 899  HQLQVQMENTLKEQKE-------LKKSLE---KEKEASHQLKLELNSMQEQLIQ-AQNTL 947

Query: 532  KVFDLSVEGSLISEDAMDNIDEILEKTE------SSVCKELEIALVDQGDADKEIISNTY 585
            K      +     +    NI+E+ + +E       ++  EL+IA++ + + + + +    
Sbjct: 948  K------QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENK-LQQQL 1000

Query: 586  SQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALL-- 643
            +Q  Q++ +E+  I+ +Q  Y+ S E  KQL        S   LL+ ++ LKS++  L  
Sbjct: 1001 TQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRES--ELLATRQDLKSVEEKLSL 1058

Query: 644  --------------RWKLVE-----KSNLEESDDPDGSQIE---KIKEEITQLRNNVFQE 681
                          + KL++     K+ LE+       Q++   K  ++I + ++   +E
Sbjct: 1059 AQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKE 1118

Query: 682  IYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSS 741
            + +E+ +   +  +  +   E+  L+ E+   K  +   +  +   + LL  + + EL  
Sbjct: 1119 LVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL-ELQG 1177

Query: 742  KRPLVRSEV-----NGQIILLKGYSVDVDTEAKVIERAATYHRAWREAE 785
            K   +++ V     N QI+  +    + + + + IE+ A  H   +E E
Sbjct: 1178 KADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKE 1226


>gi|208431829 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform b [Homo sapiens]
          Length = 510

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 14/166 (8%)

Query: 832 LKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGD 891
           L++ + + +G+  +H   +IH  L  +N+F ++ +Q  +GDF    S+          G 
Sbjct: 351 LELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGT 410

Query: 892 LSLMSPELKMGKPASPGSDLYAYGCLLL-WLSVQNQEFEINK------DGIPKVDQFHLD 944
           L  MSPE    +      DLYA G +L   L V +  FE +K      DGI   D F  D
Sbjct: 411 LRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIIS-DIF--D 467

Query: 945 DKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNPEKDTEYT 990
            K K+LL  L+    S   E   N    L        +PEK+  +T
Sbjct: 468 KKEKTLLQKLL----SKKPEDRPNTSEILRTLTVWKKSPEKNERHT 509


>gi|208431827 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform a [Homo sapiens]
          Length = 551

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 14/166 (8%)

Query: 832 LKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGD 891
           L++ + + +G+  +H   +IH  L  +N+F ++ +Q  +GDF    S+          G 
Sbjct: 392 LELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGT 451

Query: 892 LSLMSPELKMGKPASPGSDLYAYGCLLL-WLSVQNQEFEINK------DGIPKVDQFHLD 944
           L  MSPE    +      DLYA G +L   L V +  FE +K      DGI   D F  D
Sbjct: 452 LRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIIS-DIF--D 508

Query: 945 DKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNPEKDTEYT 990
            K K+LL  L+    S   E   N    L        +PEK+  +T
Sbjct: 509 KKEKTLLQKLL----SKKPEDRPNTSEILRTLTVWKKSPEKNERHT 550


>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
           2 isoform a [Homo sapiens]
          Length = 551

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 14/166 (8%)

Query: 832 LKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGD 891
           L++ + + +G+  +H   +IH  L  +N+F ++ +Q  +GDF    S+          G 
Sbjct: 392 LELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGT 451

Query: 892 LSLMSPELKMGKPASPGSDLYAYGCLLL-WLSVQNQEFEINK------DGIPKVDQFHLD 944
           L  MSPE    +      DLYA G +L   L V +  FE +K      DGI   D F  D
Sbjct: 452 LRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIIS-DIF--D 508

Query: 945 DKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNPEKDTEYT 990
            K K+LL  L+    S   E   N    L        +PEK+  +T
Sbjct: 509 KKEKTLLQKLL----SKKPEDRPNTSEILRTLTVWKKSPEKNERHT 550


>gi|110349799 testis-specific protein kinase 2 [Homo sapiens]
          Length = 571

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 49/206 (23%), Positives = 88/206 (42%), Gaps = 18/206 (8%)

Query: 746 VRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDPMA 805
           VR   +GQ++ LK  ++     A +++     +R        S    L F+ +C      
Sbjct: 75  VRHRASGQVMALKMNTLS-SNRANMLKEVQLMNRL-------SHPNILRFMGVCVHQGQL 126

Query: 806 YLMVPYYPRANLNAV-QANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFALN 864
           + +  Y    NL  +  +N+ L     +K+   +A GL  LH   I H  L   N     
Sbjct: 127 HALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKR 186

Query: 865 REQG---IVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLL 918
            E G   +V DF   +    VS  +    +VG    M+PE+   +P +  +D+++YG +L
Sbjct: 187 DENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIIL 246

Query: 919 LWLSVQNQEFEINKDGIPKVDQFHLD 944
             +  +    + + D +P+ + F LD
Sbjct: 247 CEIIAR---IQADPDYLPRTENFGLD 269


>gi|21735552 mitogen-activated protein kinase kinase kinase 12 [Homo
           sapiens]
          Length = 859

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 31/129 (24%), Positives = 63/129 (48%), Gaps = 2/129 (1%)

Query: 793 LIFLFLCKSDPMAYLMVPYYPRANLNAV-QANMPLNSEETLKVMKGVAQGLHTLHKADII 851
           + F  +C   P   +++ +  +  L  V +A  P+     +    G+A G++ LH   II
Sbjct: 174 ITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKII 233

Query: 852 HGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDL 911
           H  L   N+     +   + DF  +K +S +++     G ++ M+PE+   +P S   D+
Sbjct: 234 HRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDI 293

Query: 912 YAYGCLLLW 920
           +++G ++LW
Sbjct: 294 WSFG-VVLW 301


>gi|223671888 interleukin-1 receptor-associated kinase 4 isoform b
           [Homo sapiens]
          Length = 336

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 807 LMVPYYPRANL----NAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFA 862
           L+  Y P  +L    + +    PL+     K+ +G A G++ LH+   IH  +   N+  
Sbjct: 136 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 195

Query: 863 LNREQGIVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLL 919
                  + DF   ++    +Q    + +VG  + M+PE   G+  +P SD+Y++G +LL
Sbjct: 196 DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGE-ITPKSDIYSFGVVLL 254

Query: 920 WLSVQNQEFEINKDGIPKVDQ 940
            +            G+P VD+
Sbjct: 255 EIIT----------GLPAVDE 265


>gi|223671885 interleukin-1 receptor-associated kinase 4 isoform b
           [Homo sapiens]
          Length = 336

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 807 LMVPYYPRANL----NAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFA 862
           L+  Y P  +L    + +    PL+     K+ +G A G++ LH+   IH  +   N+  
Sbjct: 136 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 195

Query: 863 LNREQGIVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLL 919
                  + DF   ++    +Q    + +VG  + M+PE   G+  +P SD+Y++G +LL
Sbjct: 196 DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGE-ITPKSDIYSFGVVLL 254

Query: 920 WLSVQNQEFEINKDGIPKVDQ 940
            +            G+P VD+
Sbjct: 255 EIIT----------GLPAVDE 265


>gi|223671883 interleukin-1 receptor-associated kinase 4 isoform b
           [Homo sapiens]
          Length = 336

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 807 LMVPYYPRANL----NAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFA 862
           L+  Y P  +L    + +    PL+     K+ +G A G++ LH+   IH  +   N+  
Sbjct: 136 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 195

Query: 863 LNREQGIVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLL 919
                  + DF   ++    +Q    + +VG  + M+PE   G+  +P SD+Y++G +LL
Sbjct: 196 DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGE-ITPKSDIYSFGVVLL 254

Query: 920 WLSVQNQEFEINKDGIPKVDQ 940
            +            G+P VD+
Sbjct: 255 EIIT----------GLPAVDE 265


>gi|166795293 interleukin-1 receptor-associated kinase 4 isoform a
           [Homo sapiens]
          Length = 460

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 807 LMVPYYPRANL----NAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFA 862
           L+  Y P  +L    + +    PL+     K+ +G A G++ LH+   IH  +   N+  
Sbjct: 260 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 319

Query: 863 LNREQGIVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLL 919
                  + DF   ++    +Q    + +VG  + M+PE   G+  +P SD+Y++G +LL
Sbjct: 320 DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGE-ITPKSDIYSFGVVLL 378

Query: 920 WLSVQNQEFEINKDGIPKVDQ 940
            +            G+P VD+
Sbjct: 379 EIIT----------GLPAVDE 389


>gi|166795295 interleukin-1 receptor-associated kinase 4 isoform a
           [Homo sapiens]
          Length = 460

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 807 LMVPYYPRANL----NAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFA 862
           L+  Y P  +L    + +    PL+     K+ +G A G++ LH+   IH  +   N+  
Sbjct: 260 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 319

Query: 863 LNREQGIVGDFDFTKS---VSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLL 919
                  + DF   ++    +Q    + +VG  + M+PE   G+  +P SD+Y++G +LL
Sbjct: 320 DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGE-ITPKSDIYSFGVVLL 378

Query: 920 WLSVQNQEFEINKDGIPKVDQ 940
            +            G+P VD+
Sbjct: 379 EIIT----------GLPAVDE 389


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 100/483 (20%), Positives = 198/483 (40%), Gaps = 61/483 (12%)

Query: 265 LDLKDE--NDAGNLITFPKESLAVGDFNLGSNV-SLEKIKQDQKLIE-ENEKLKTEKDAL 320
           LD KD+  N    L    K+ +   D  L S     EKI+++   ++ ENE  K E   +
Sbjct: 428 LDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV 487

Query: 321 LESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEIL--KEMR 378
           L++ + L +  +Q +QE++ +  A   LT+ L     T + T  + L+   E+   ++ R
Sbjct: 488 LQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTT-LTTTQRELSQLQELSNHQKKR 546

Query: 379 HVDISVRFGKDLSDAIQVLDEGCFTTPASLNGL---EIIWAEYSLAQENIKTCEYVSEGN 435
             +I     KDL +   ++      T A +NG+   E   A   +++   +    V+   
Sbjct: 547 ATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSK 606

Query: 436 ILIAQRNEMQQKLYMSVEDF-ILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGAN--SD 492
            L + + +  +K+  S  +    ++  S    ++K+L D   ++E    Q +E  +  S+
Sbjct: 607 QLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE 666

Query: 493 EILK----------KFYD--------------WKCDKREEFTSVRSETDASLHRLVAWFQ 528
           E+ K           F D               K    ++  S R      L RL    +
Sbjct: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIE 726

Query: 529 RTLKVF----DLSVEGSLISEDAMDNIDEI-LEKTESSVCKELEIALVD---QGDADKEI 580
              K+     DL+ +  L  E    + +++ +E  E  +  E  + L D   Q   D + 
Sbjct: 727 EKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKG 786

Query: 581 ISNTYSQVLQKIHSEERL-IATVQAKYKDSIEF----------KKQLIEYLNKSPSVDHL 629
           +  T S+ LQ +H+  +L +  +  + K S+E           +KQ I +L    +++ L
Sbjct: 787 LEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLEN--NLEQL 844

Query: 630 LSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREEY 689
             + K L    A LR +L     LE+       +++ ++  + + + N  ++    ++E 
Sbjct: 845 TKVHKQLVRDNADLRCEL---PKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEV 901

Query: 690 EML 692
           + +
Sbjct: 902 DRI 904


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 15/154 (9%)

Query: 776 TYHRAWREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVM 835
           TY  +W   EG  GLL ++  F    D    L             Q    L   + ++  
Sbjct: 67  TYKESW---EGGDGLLYIVMGFCEGGDLYRKLKE-----------QKGQLLPENQVVEWF 112

Query: 836 KGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASV-NMMVGDLSL 894
             +A  L  LH+  I+H  L   NVF        VGD    + +     + + ++G    
Sbjct: 113 VQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYY 172

Query: 895 MSPELKMGKPASPGSDLYAYGCLLLWLSVQNQEF 928
           MSPEL   KP +  SD++A GC +  ++     F
Sbjct: 173 MSPELFSNKPYNYKSDVWALGCCVYEMATLKHAF 206


>gi|66932999 testis-specific protein kinase 1 [Homo sapiens]
          Length = 626

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 12/161 (7%)

Query: 793 LIFLFLCKSDPMAYLMVPYYPRANLNAVQANM-PLNSEETLKVMKGVAQGLHTLHKADII 851
           L F+ +C      + +  Y     L  + ++  PL+    L +   +A+GL  LH   + 
Sbjct: 113 LRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVF 172

Query: 852 HGSLHQNNVFALNREQG---IVGDFDFTKSV-----SQRASVNMMVGDLSLMSPELKMGK 903
           H  L   N      ++G   +VGDF   + +       R     +VG    M+PE+  G+
Sbjct: 173 HRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGE 232

Query: 904 PASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLD 944
                +D++A+G +L  L  +      + D +P+ + F LD
Sbjct: 233 LYDEKADVFAFGIVLCELIAR---VPADPDYLPRTEDFGLD 270


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 91/427 (21%), Positives = 182/427 (42%), Gaps = 50/427 (11%)

Query: 301  KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI 360
            KQ + L EE E LKTE +  L++  A +    +  QE+ + K A  + T + E  ++   
Sbjct: 1139 KQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQ--- 1195

Query: 361  DTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL 420
            D R ++  A  E+ +++     + RF  +L    Q L+         +  L+ + AE   
Sbjct: 1196 DMRQRHATALEELSEQLEQ---AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEH 1252

Query: 421  AQENI-----KTCEYVSEGNILIAQRNEMQQKLYMSVEDF--ILE----------VDESS 463
             ++ +     +    VSEG+ L  +  E   KL   +++   +LE           D +S
Sbjct: 1253 KRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAAS 1312

Query: 464  LNKRLKTLQDL-------SVSLEAVYGQAKEGANS--------DEILKKFYDWKCDKREE 508
            L  +L+  Q+L        ++L +   Q +E  NS        +E  K         + +
Sbjct: 1313 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQ 1372

Query: 509  FTSVRSETDASLHRLVAWFQRTLKVF-DLSVEGSLISEDAMDNIDEILEKTESSVCKELE 567
                + + D  L  + +  +   K+  D       + E A+    + LEKT++ + +EL+
Sbjct: 1373 LADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL--AYDKLEKTKNRLQQELD 1430

Query: 568  IALVDQGDADKEIISN--TYSQVLQKIHSEERLIATVQAKYKD--SIEFKKQLIEYLNKS 623
               VD  D  +++ SN     +   ++ +EE+ I+   A+ +D    E +++  + L+ +
Sbjct: 1431 DLTVDL-DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLA 1489

Query: 624  PSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIY 683
             +++  L  K+  +     LR    +  +L  S D  G  + ++++    L   V +E+ 
Sbjct: 1490 RALEEALEAKEEFERQNKQLR---ADMEDLMSSKDDVGKNVHELEKSKRALEQQV-EEMR 1545

Query: 684  HEREEYE 690
             + EE E
Sbjct: 1546 TQLEELE 1552



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 89/420 (21%), Positives = 179/420 (42%), Gaps = 57/420 (13%)

Query: 295  VSLEKIKQDQKLIEENEK---LKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLT-- 349
            + LEK+  + K+ +  E+   L+ +    ++  K +E ++ + + +L +E+  A +L   
Sbjct: 969  LQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKI 1028

Query: 350  -NHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASL 408
             N  E  +    +   K    + E+ K  R +D       DL D I  L        A +
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT---DLQDQIAELQ-------AQI 1078

Query: 409  NGLEIIWAEY------SLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDES 462
            + L++  A+       +LA+ + +T   + + N L   R E+Q ++    EDF  E +++
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDET---LHKNNALKVVR-ELQAQIAELQEDF--ESEKA 1132

Query: 463  SLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHR 522
            S NK  K  +DLS  LEA+  + ++  ++    ++    +  + +E   ++   +     
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQEL---RTKREQEVAELKKALEEETKN 1189

Query: 523  LVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSV---CKEL--EIALVDQGDAD 577
              A  Q   +    ++E      +        LEK +  +    KEL  E+ ++ Q  A+
Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAE 1249

Query: 578  KEIISNTYSQVLQKIHSE----ERL---IATVQAKYKDSIEFKKQLIEYLNKS--PSVDH 628
             E         +Q++H++    +RL   +A   +K ++ ++    L+E   K        
Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309

Query: 629  LLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREE 688
              S++  L+  + LL+ +  +K NL        S+I +++EE      N  QE   E EE
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNL-------SSRIRQLEEE-----KNSLQEQQEEEEE 1357



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 49/207 (23%), Positives = 94/207 (45%), Gaps = 13/207 (6%)

Query: 301  KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI 360
            ++  +L +E     + K ALL+  + LE ++ Q+ +EL++E+ + ++L N         +
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQ-SNMELLNDRFRKTTLQV 1766

Query: 361  DTRMKNLAAKMEILKEMRHVDISV-RFGKDLSDAIQVLDEGCFTT--PASLNGLE--IIW 415
            DT    LAA+    ++  +    + R  K+L   +Q L EG   +   A+++ LE  I  
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQEL-EGAVKSKFKATISALEAKIGQ 1825

Query: 416  AEYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDE--SSLNKRLKTLQD 473
             E  L QE     +  +  N L+ +  +  ++++M VED     D+    + K    ++ 
Sbjct: 1826 LEEQLEQE----AKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881

Query: 474  LSVSLEAVYGQAKEGANSDEILKKFYD 500
            L   LE    +A     S   L++  D
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELD 1908


>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
           [Homo sapiens]
          Length = 556

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 838 VAQGLHTLHKADIIHGSLHQNNVFALNREQGI-VGDFDFTKSVS---QRASVNMMVGDLS 893
           +   L  LH   IIH  L   N+  LN +  I + DF   K +S   ++A  N  VG   
Sbjct: 189 IVSALEYLHGKGIIHRDLKPENIL-LNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQ 247

Query: 894 LMSPELKMGKPASPGSDLYAYGCLLLWL 921
            +SPEL   K A   SDL+A GC++  L
Sbjct: 248 YVSPELLTEKSACKSSDLWALGCIIYQL 275


>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
           protein kinase-1 [Homo sapiens]
          Length = 471

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 838 VAQGLHTLHKADIIHGSLHQNNVFALNREQGI-VGDFDFTKSVS---QRASVNMMVGDLS 893
           +   L  LH   IIH  L   N+  LN +  I + DF   K +S   ++A  N  VG   
Sbjct: 208 IVSALEYLHGKGIIHRDLKPENIL-LNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQ 266

Query: 894 LMSPELKMGKPASPGSDLYAYGCLLLWL 921
            +SPEL   K A   SDL+A GC++  L
Sbjct: 267 YVSPELLTEKSACKSSDLWALGCIIYQL 294


>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
           sapiens]
          Length = 396

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 838 VAQGLHTLHKADIIHGSLHQNNVFALNREQGI-VGDFDFTKSVS---QRASVNMMVGDLS 893
           +   L  LH   IIH  L   N+  LN +  I + DF   K +S   ++A  N  VG   
Sbjct: 162 IVSALEYLHGKGIIHRDLKPENIL-LNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQ 220

Query: 894 LMSPELKMGKPASPGSDLYAYGCLLLWL 921
            +SPEL   K A   SDL+A GC++  L
Sbjct: 221 YVSPELLTEKSACKSSDLWALGCIIYQL 248


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 9/146 (6%)

Query: 806 YLMVPYYPRANLNAVQANMP--LNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 863
           YL+  Y  +  L  ++  MP  +  E+    +  + + +H  HK DI+H  +   N+   
Sbjct: 86  YLVFEYVEKNMLELLE-EMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLIS 144

Query: 864 NREQGIVGDFDFTKSVSQ--RASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWL 921
           + +   + DF F +++S+   A+    V      SPEL +G P     D+++ GC+L  L
Sbjct: 145 HNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGEL 204

Query: 922 SVQNQEFEINKDGIPKVDQFHLDDKV 947
           S     F     G  ++DQ     KV
Sbjct: 205 SDGQPLF----PGESEIDQLFTIQKV 226


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 9/146 (6%)

Query: 806 YLMVPYYPRANLNAVQANMP--LNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFAL 863
           YL+  Y  +  L  ++  MP  +  E+    +  + + +H  HK DI+H  +   N+   
Sbjct: 86  YLVFEYVEKNMLELLE-EMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLIS 144

Query: 864 NREQGIVGDFDFTKSVSQ--RASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWL 921
           + +   + DF F +++S+   A+    V      SPEL +G P     D+++ GC+L  L
Sbjct: 145 HNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGEL 204

Query: 922 SVQNQEFEINKDGIPKVDQFHLDDKV 947
           S     F     G  ++DQ     KV
Sbjct: 205 SDGQPLF----PGESEIDQLFTIQKV 226


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/403 (20%), Positives = 167/403 (41%), Gaps = 66/403 (16%)

Query: 297 LEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTL 356
           ++ ++ +QK + + E L+ +   +LE  +AL+ +++Q   ++  + +A+V     L   L
Sbjct: 551 MQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASV-----LAEEL 605

Query: 357 KTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWA 416
              I  + K +    + L   R  D      ++L D IQ ++   F   A +  L+ +  
Sbjct: 606 HKVIAEKDKQIKQTEDSLASER--DRLTSKEEELKD-IQNMN---FLLKAEVQKLQALAN 659

Query: 417 EYSLAQ---ENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDF-ILEVDESSLNKRLKTLQ 472
           E + A    E ++   YV +  I + +  ++Q ++   +E+F IL     +L   ++ LQ
Sbjct: 660 EQAAAAHELEKMQQSVYVKDDKIRLLE-EQLQHEISNKMEEFKILNDQNKALKSEVQKLQ 718

Query: 473 DLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLK 532
            L            E  N D +            E+      E D             LK
Sbjct: 719 TL----------VSEQPNKDVV------------EQMEKCIQEKD-----------EKLK 745

Query: 533 VFDLSVEGSLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKI 592
             +  +E  LI     +     +    SS+ KE++     Q   D+   ++   ++ + I
Sbjct: 746 TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQN--DQVSFASLVEELKKVI 803

Query: 593 HSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVE--- 649
           H ++  I +V+         + +L++  NK  +V   LSI   ++ L+ LL+ K  +   
Sbjct: 804 HEKDGKIKSVEEL------LEAELLKVANKEKTVQ--LSITSKVQELQNLLKGKEEQMNT 855

Query: 650 -KSNLEESDDP---DGSQIEKIKEEITQLRNNVFQEIYHEREE 688
            K+ LEE +      G  ++ ++EE   L+ +V +   H  +E
Sbjct: 856 MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 898


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,613,855
Number of Sequences: 37866
Number of extensions: 1546502
Number of successful extensions: 5930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 501
Number of HSP's that attempted gapping in prelim test: 5171
Number of HSP's gapped (non-prelim): 1173
length of query: 1019
length of database: 18,247,518
effective HSP length: 112
effective length of query: 907
effective length of database: 14,006,526
effective search space: 12703919082
effective search space used: 12703919082
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.