Guide to the Human Genome
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Name: IRAK4 Sequence: fasta or formatted (460aa) NCBI GI: 166795295
Description:

interleukin-1 receptor-associated kinase 4 isoform a

Referenced in:

Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt mRNA [460aa] interleukin-1 receptor-associated kinase 4 isoform a
alt prot [336aa] interleukin-1 receptor-associated kinase 4 isoform b
alt prot [336aa] interleukin-1 receptor-associated kinase 4 isoform b
alt prot [336aa] interleukin-1 receptor-associated kinase 4 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         29           2
 C cysteine            1.7          8           1
 D aspartate           7.0         32           2
 E glutamate           7.2         33           2
 F phenylalanine       4.1         19           2
 G glycine             5.2         24           2
 H histidine           2.2         10           2
 I isoleucine          5.7         26           2
 K lysine              7.4         34           2
 L leucine             9.8         45           3
 M methionine          3.0         14           1
 N asparagine          4.8         22           2
 P proline             5.0         23           2
 Q glutamine           4.3         20           2
 R arginine            3.5         16           2
 S serine              7.0         32           3
 T threonine           6.3         29           2
 V valine              6.3         29           2
 W tryptophan          0.7          3           1
 Y tyrosine            2.6         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   interleukin-1 receptor-associated kinase 4 isoform ... 
IRAK4                 1.000   interleukin-1 receptor-associated kinase 4 isoform ...
IRAK4                 0.723   interleukin-1 receptor-associated kinase 4 isoform ...
IRAK4                 0.723   interleukin-1 receptor-associated kinase 4 isoform ...
IRAK4                 0.723   interleukin-1 receptor-associated kinase 4 isoform ...
IRAK1                 0.169   interleukin-1 receptor-associated kinase 1 isoform 1...
IRAK1                 0.165   interleukin-1 receptor-associated kinase 1 isoform 2...
IRAK1                 0.161   interleukin-1 receptor-associated kinase 1 isoform 3...
IRAK3                 0.150   interleukin-1 receptor-associated kinase 3 isoform ...
IRAK2                 0.137   interleukin-1 receptor-associated kinase 2 
IRAK3                 0.133   interleukin-1 receptor-associated kinase 3 isoform ...
BRAF                  0.106   B-Raf 
RAF1                  0.100   v-raf-1 murine leukemia viral oncogene homolog 1 [Hom...
LCK                   0.090   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.090   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.089   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.089   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
BLK                   0.089   B lymphoid tyrosine kinase 
MATK                  0.088   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.088   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.088   megakaryocyte-associated tyrosine kinase isoform a [...
SRC                   0.087   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.087   proto-oncogene tyrosine-protein kinase SRC 
MAP3K13               0.087   mitogen-activated protein kinase kinase kinase 13 [Ho...
YES1                  0.087   viral oncogene yes-1 homolog 1 
ARAF                  0.087   v-raf murine sarcoma 3611 viral oncogene homolog [Hom...
MST4                  0.086   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.086   serine/threonine kinase 24 isoform b 
STK24                 0.086   serine/threonine kinase 24 isoform a 
MAP3K10               0.085   mitogen-activated protein kinase kinase kinase 10 [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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