Search of human proteins with 14591904

Search of human proteins with 14591904

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14591904 RecQ protein-like [Homo sapiens]
         (649 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14591902 RecQ protein-like [Homo sapiens]                         1301   0.0  
gi|14591904 RecQ protein-like [Homo sapiens]                         1301   0.0  
gi|4557365 Bloom syndrome protein [Homo sapiens]                      369   e-102
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]             276   4e-74
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]              261   1e-69
gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]              261   1e-69
gi|110735439 Werner syndrome protein [Homo sapiens]                   248   1e-65
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent...   248   1e-65
gi|116812616 RecQ protein-like 4 [Homo sapiens]                       170   4e-42
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]             65   3e-10
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]             65   3e-10
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]          57   7e-08
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]           57   7e-08
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    56   1e-07
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...    54   6e-07
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...    53   8e-07
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...    53   8e-07
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    52   1e-06
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    52   2e-06
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       52   2e-06
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    52   2e-06
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...    50   5e-06
gi|110556640 DNA helicase HEL308 [Homo sapiens]                        50   5e-06
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                   49   1e-05
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...    49   1e-05
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...    49   1e-05
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...    49   2e-05
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]     47   5e-05
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...    45   2e-04
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...    45   2e-04

>gi|14591902 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 1301 bits (3368), Expect = 0.0
 Identities = 649/649 (100%), Positives = 649/649 (100%)

Query: 1   MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE 60
           MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
Sbjct: 1   MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE 60

Query: 61  YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS 120
           YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
Sbjct: 61  YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS 120

Query: 121 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK 180
           LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
Sbjct: 121 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK 180

Query: 181 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI 240
           NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
Sbjct: 181 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI 240

Query: 241 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF 300
           LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
Sbjct: 241 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF 300

Query: 301 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW 360
           IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
Sbjct: 301 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW 360

Query: 361 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF 420
           SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
Sbjct: 361 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF 420

Query: 421 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK 480
           GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
Sbjct: 421 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK 480

Query: 481 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE 540
           DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
Sbjct: 481 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE 540

Query: 541 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA 600
           DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
Sbjct: 541 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA 600

Query: 601 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA 649
           ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
Sbjct: 601 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA 649


>gi|14591904 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 1301 bits (3368), Expect = 0.0
 Identities = 649/649 (100%), Positives = 649/649 (100%)

Query: 1   MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE 60
           MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
Sbjct: 1   MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE 60

Query: 61  YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS 120
           YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
Sbjct: 61  YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS 120

Query: 121 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK 180
           LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
Sbjct: 121 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK 180

Query: 181 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI 240
           NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
Sbjct: 181 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI 240

Query: 241 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF 300
           LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
Sbjct: 241 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF 300

Query: 301 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW 360
           IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
Sbjct: 301 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW 360

Query: 361 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF 420
           SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
Sbjct: 361 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF 420

Query: 421 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK 480
           GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
Sbjct: 421 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK 480

Query: 481 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE 540
           DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
Sbjct: 481 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE 540

Query: 541 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA 600
           DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
Sbjct: 541 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA 600

Query: 601 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA 649
           ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
Sbjct: 601 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA 649


>gi|4557365 Bloom syndrome protein [Homo sapiens]
          Length = 1417

 Score =  369 bits (948), Expect = e-102
 Identities = 208/552 (37%), Positives = 313/552 (56%), Gaps = 31/552 (5%)

Query: 73   FPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDG 132
            FP + ++  I    F L  FR  QLE IN  + G++ F++MPTGGGKSLCYQLPA  S G
Sbjct: 649  FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG 708

Query: 133  FTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPE 192
             T+VI PL SL+ DQ+  L  L I AT L    +      ++ ++  K+  +KL+YVTPE
Sbjct: 709  VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPE 768

Query: 193  KIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIG 252
            KI  S   +S LE  YE +   R  +DE HC SQWGHDFR DYK + +L+++FP+  ++ 
Sbjct: 769  KICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMA 828

Query: 253  LTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY 312
            LTATA   V  D    L I +   F+ SFNR NL Y V  K      F  D ++ I   +
Sbjct: 829  LTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAF--DCLEWIRKHH 886

Query: 313  KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW-SANEIQVVVAT 371
               SGIIYC S+++ + +  +LQ  G+ A AYHA L    +  V +KW + +  QV+ AT
Sbjct: 887  PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT 946

Query: 372  VAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVV 431
            +AFGMGIDKPDVRFVIH S+ KS+E YYQESGRAGRD   + C+L+Y + D+ R+  +++
Sbjct: 947  IAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIM 1006

Query: 432  MENVGQ--------QKLYEMVSYCQNISKCRRVLMAQHFDE-VWNSEACNK----MCDNC 478
            ME  G           LY MV YC+NI++CRR+ +  +F E  +N + C K     CDNC
Sbjct: 1007 MEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNC 1066

Query: 479  CKDSAFERKNITEYCRDLIKILKQAEEL-----------NEKLTPLKLIDSWMGKGAAKL 527
            CK   ++ +++T+  + +++ +++               + + T   L+D ++G  +AK+
Sbjct: 1067 CKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKI 1126

Query: 528  RVAGVV--APTLPREDLEKIIAHFLIQQYLKEDYSFTAY-ATISYLKIGPKANLLNNEAH 584
            + +G+        R + E++    ++ + L ED    A    I+Y+ +G KA  + N   
Sbjct: 1127 Q-SGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNL 1185

Query: 585  AITMQVTKSTQN 596
             +    T+++ +
Sbjct: 1186 KVDFMETENSSS 1197


>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
          Length = 991

 Score =  276 bits (706), Expect = 4e-74
 Identities = 161/433 (37%), Positives = 242/433 (55%), Gaps = 27/433 (6%)

Query: 78  KVKDILQNVFKLEKFR-PLQLE-TINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTL 135
           +V+  L+ VF  + F+ PLQ   T+ V    K+VF+ MPTG GKSLCYQLPAL + G T+
Sbjct: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITI 74

Query: 136 VICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIA 195
           V+ PLI+L++DQ+  L  L +  + LN+  S +  K + A++  +  + K++Y+TPE +A
Sbjct: 75  VVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPE-MA 133

Query: 196 KSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTA 255
            S  F   L         + + VDE HC SQWGHDFRPDY  LG L+ +  +A  + LTA
Sbjct: 134 ASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTA 193

Query: 256 TATNHVLTDAQKILCIEKCFT-FTASFNRPNLYYEVRQKP------SNTEDFIEDIVKLI 308
           TAT  V  D    L ++K    F     R NL+Y+V+ K        N +DF    +   
Sbjct: 194 TATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQE 253

Query: 309 NGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVV 368
             +     GI+YC +++  EQ+ + L   G++A AYHA L+  ++T V   W   ++ V+
Sbjct: 254 ADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVI 313

Query: 369 VATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISS 428
           VAT++FGMG+DK +VRFV H +++KSM  YYQESGRAGRD   + C LYY   D  ++S 
Sbjct: 314 VATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSF 373

Query: 429 MVVMENVGQQK--------------LYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKM 474
           ++  E    Q+                 +V++C+ +  CR   +A++F +     AC K 
Sbjct: 374 LIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG-CRHAAIAKYFGDA--LPACAKG 430

Query: 475 CDNCCKDSAFERK 487
           CD+C   +A  R+
Sbjct: 431 CDHCQNPTAVRRR 443


>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
          Length = 410

 Score =  261 bits (668), Expect = 1e-69
 Identities = 146/365 (40%), Positives = 214/365 (58%), Gaps = 10/365 (2%)

Query: 78  KVKDILQNVFKLEKFR-PLQLE-TINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTL 135
           +V+  L+ VF  + F+ PLQ   T+ V    K+VF+ MPTG GKSLCYQLPAL + G T+
Sbjct: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITI 74

Query: 136 VICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIA 195
           V+ PLI+L++DQ+  L  L +  + LN+  S +  K + A++  +  + K++Y+TPE +A
Sbjct: 75  VVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPE-MA 133

Query: 196 KSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTA 255
            S  F   L         + + VDE HC SQWGHDFRPDY  LG L+ +  +A  + LTA
Sbjct: 134 ASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTA 193

Query: 256 TATNHVLTDAQKILCIEKCFT-FTASFNRPNLYYEVRQKP------SNTEDFIEDIVKLI 308
           TAT  V  D    L ++K    F     R NL+Y+V+ K        N +DF    +   
Sbjct: 194 TATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQE 253

Query: 309 NGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVV 368
             +     GI+YC +++  EQ+ + L   G++A AYHA L+  ++T V   W   ++ V+
Sbjct: 254 ADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVI 313

Query: 369 VATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISS 428
           VAT++FGMG+DK +VRFV H +++KSM  YYQESGRAGRD   + C LYY   D  ++S 
Sbjct: 314 VATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSF 373

Query: 429 MVVME 433
           ++  E
Sbjct: 374 LIRKE 378


>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
          Length = 435

 Score =  261 bits (668), Expect = 1e-69
 Identities = 146/365 (40%), Positives = 214/365 (58%), Gaps = 10/365 (2%)

Query: 78  KVKDILQNVFKLEKFR-PLQLE-TINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTL 135
           +V+  L+ VF  + F+ PLQ   T+ V    K+VF+ MPTG GKSLCYQLPAL + G T+
Sbjct: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITI 74

Query: 136 VICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIA 195
           V+ PLI+L++DQ+  L  L +  + LN+  S +  K + A++  +  + K++Y+TPE +A
Sbjct: 75  VVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPE-MA 133

Query: 196 KSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTA 255
            S  F   L         + + VDE HC SQWGHDFRPDY  LG L+ +  +A  + LTA
Sbjct: 134 ASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTA 193

Query: 256 TATNHVLTDAQKILCIEKCFT-FTASFNRPNLYYEVRQKP------SNTEDFIEDIVKLI 308
           TAT  V  D    L ++K    F     R NL+Y+V+ K        N +DF    +   
Sbjct: 194 TATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQE 253

Query: 309 NGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVV 368
             +     GI+YC +++  EQ+ + L   G++A AYHA L+  ++T V   W   ++ V+
Sbjct: 254 ADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVI 313

Query: 369 VATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISS 428
           VAT++FGMG+DK +VRFV H +++KSM  YYQESGRAGRD   + C LYY   D  ++S 
Sbjct: 314 VATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSF 373

Query: 429 MVVME 433
           ++  E
Sbjct: 374 LIRKE 378


>gi|110735439 Werner syndrome protein [Homo sapiens]
          Length = 1432

 Score =  248 bits (634), Expect = 1e-65
 Identities = 159/481 (33%), Positives = 249/481 (51%), Gaps = 35/481 (7%)

Query: 51  EDSDAGASNEYDSSPAAWNKEDFPWSGKVKD---ILQNVFKLEKFRPLQLETIN-VTMAG 106
           E+ D   +NE +      + +DF W    ++    L+  F    F+P+Q + I+ V    
Sbjct: 509 EEDDENEANEGEED----DDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEER 564

Query: 107 KEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS 166
           ++   VM TG GKSLC+Q P +      LVI PLISLMEDQ++ LK   I A  L ++ S
Sbjct: 565 RDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQS 624

Query: 167 KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQ 226
           +  +  +      K  + +++YVTPE  + +   + +LE        T IAVDE HC S+
Sbjct: 625 ENVLTDI------KLGKYRIVYVTPEYCSGNMGLLQQLEADIG---ITLIAVDEAHCISE 675

Query: 227 WGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNL 286
           WGHDFR  ++ LG LK   P   ++ LTATA++ +  D  + L +         F+RPNL
Sbjct: 676 WGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNL 735

Query: 287 YYEVRQKPSNTEDFIEDIVKLINGRYKGQSG-IIYCFSQKDSEQVTVSLQNLGIHAGAYH 345
           Y EVR+K  N    ++  +   +  ++ +   IIYC S+K ++QVT  L+ L +  G YH
Sbjct: 736 YLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYH 795

Query: 346 ANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA 405
           A +    +  +H ++  +EIQ V+AT+AFGMGI+K D+R VIH+   K ME+YYQE GRA
Sbjct: 796 AGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRA 855

Query: 406 GRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQ-----NISKCRRVLMAQ 460
           GRD +++ C + +   DI     ++      + +LY++    +     + S+CRR ++  
Sbjct: 856 GRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILS 915

Query: 461 HFDEVWNSEA------CNKMCDNC------CKDSAFERKNITEYCRDLIKILKQAEELNE 508
           HF++    +A        K CDNC      C           ++     K+L   + L E
Sbjct: 916 HFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGE 975

Query: 509 K 509
           K
Sbjct: 976 K 976


>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
           helicase, partial [Homo sapiens]
          Length = 1140

 Score =  248 bits (634), Expect = 1e-65
 Identities = 159/481 (33%), Positives = 249/481 (51%), Gaps = 35/481 (7%)

Query: 51  EDSDAGASNEYDSSPAAWNKEDFPWSGKVKD---ILQNVFKLEKFRPLQLETIN-VTMAG 106
           E+ D   +NE +      + +DF W    ++    L+  F    F+P+Q + I+ V    
Sbjct: 217 EEDDENEANEGEED----DDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEER 272

Query: 107 KEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS 166
           ++   VM TG GKSLC+Q P +      LVI PLISLMEDQ++ LK   I A  L ++ S
Sbjct: 273 RDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQS 332

Query: 167 KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQ 226
           +  +  +      K  + +++YVTPE  + +   + +LE        T IAVDE HC S+
Sbjct: 333 ENVLTDI------KLGKYRIVYVTPEYCSGNMGLLQQLEADIG---ITLIAVDEAHCISE 383

Query: 227 WGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNL 286
           WGHDFR  ++ LG LK   P   ++ LTATA++ +  D  + L +         F+RPNL
Sbjct: 384 WGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNL 443

Query: 287 YYEVRQKPSNTEDFIEDIVKLINGRYKGQSG-IIYCFSQKDSEQVTVSLQNLGIHAGAYH 345
           Y EVR+K  N    ++  +   +  ++ +   IIYC S+K ++QVT  L+ L +  G YH
Sbjct: 444 YLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYH 503

Query: 346 ANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA 405
           A +    +  +H ++  +EIQ V+AT+AFGMGI+K D+R VIH+   K ME+YYQE GRA
Sbjct: 504 AGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRA 563

Query: 406 GRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQ-----NISKCRRVLMAQ 460
           GRD +++ C + +   DI     ++      + +LY++    +     + S+CRR ++  
Sbjct: 564 GRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILS 623

Query: 461 HFDEVWNSEA------CNKMCDNC------CKDSAFERKNITEYCRDLIKILKQAEELNE 508
           HF++    +A        K CDNC      C           ++     K+L   + L E
Sbjct: 624 HFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGE 683

Query: 509 K 509
           K
Sbjct: 684 K 684


>gi|116812616 RecQ protein-like 4 [Homo sapiens]
          Length = 1208

 Score =  170 bits (430), Expect = 4e-42
 Identities = 123/371 (33%), Positives = 194/371 (52%), Gaps = 41/371 (11%)

Query: 76  SGKVKDILQNVFKL------EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC 129
           SG++ +    VF+       + FRP Q   +   ++G    LV+PTG GKSLCYQLPAL 
Sbjct: 459 SGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALL 518

Query: 130 ----SDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELK 185
               S   TLV+ PL+SLM+DQ+  L    + A  +++  +++  + V  ++  + +++ 
Sbjct: 519 YSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKI--RAAQVH 575

Query: 186 LIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDY-KALGILKRQ 244
           ++ +TPE +  +      L  A +        +DE HC SQW H+FRP Y +   +L+ +
Sbjct: 576 VLMLTPEALVGA----GGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRER 631

Query: 245 FPNASLIGLTATATNHVLTD-AQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIED 303
                 +GLTATAT    +D AQ +   E+      +    NL+  V    S   D  + 
Sbjct: 632 MGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSV----SMDRDTDQA 687

Query: 304 IVKLING-RYKG-QSGIIYCFSQKDSEQVTVSLQNLGIHAG---------------AYHA 346
           ++ L+ G R++   S IIYC  ++D+E++   L+   +HA                AYHA
Sbjct: 688 LLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTC-LHAAWVPGSGGRAPKTTAEAYHA 746

Query: 347 NLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAG 406
            +   ++  V R +   +++VVVATVAFGMG+D+PDVR V+H  +  S E+Y Q  GRAG
Sbjct: 747 GMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAG 806

Query: 407 RDDMKADCILY 417
           RD   A C L+
Sbjct: 807 RDGQPAHCHLF 817


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 66/349 (18%), Positives = 141/349 (40%), Gaps = 70/349 (20%)

Query: 94  PLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC----------SDG-FTLVICPLIS 142
           P+Q + + V ++G+++  +  TG GK+  +  P L            DG   +++CP   
Sbjct: 278 PIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRE 337

Query: 143 LMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMS 202
           L +      K+ G +  + + +       W  A+ + + +E+  +  TP ++        
Sbjct: 338 LCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEI--VVCTPGRLIDHVK--- 392

Query: 203 RLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL 262
             +KA   +R + +  DE       G +++                       +  +HV 
Sbjct: 393 --KKATNLQRVSYLVFDEADRMFDMGFEYQ---------------------VRSIASHVR 429

Query: 263 TDAQKILCIEKCFTFTASFN-------RPNLYYEVRQKPSNTEDFIEDIVKLINGRYKG- 314
            D Q +L       F+A+F        R  L   +R    +  +  ED+ +++   + G 
Sbjct: 430 PDRQTLL-------FSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGP 482

Query: 315 --------------QSGIIYCFSQK--DSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHR 358
                          SG +  F  K  ++E++  +L+  G + G  H +++  ++  V  
Sbjct: 483 SKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVIS 542

Query: 359 KWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
            +   +I V+VAT     G+D P ++ VI++ +++ ++ +    GR GR
Sbjct: 543 DFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGR 591


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 66/349 (18%), Positives = 141/349 (40%), Gaps = 70/349 (20%)

Query: 94  PLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALC----------SDG-FTLVICPLIS 142
           P+Q + + V ++G+++  +  TG GK+  +  P L            DG   +++CP   
Sbjct: 278 PIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRE 337

Query: 143 LMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMS 202
           L +      K+ G +  + + +       W  A+ + + +E+  +  TP ++        
Sbjct: 338 LCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEI--VVCTPGRLIDHVK--- 392

Query: 203 RLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL 262
             +KA   +R + +  DE       G +++                       +  +HV 
Sbjct: 393 --KKATNLQRVSYLVFDEADRMFDMGFEYQ---------------------VRSIASHVR 429

Query: 263 TDAQKILCIEKCFTFTASFN-------RPNLYYEVRQKPSNTEDFIEDIVKLINGRYKG- 314
            D Q +L       F+A+F        R  L   +R    +  +  ED+ +++   + G 
Sbjct: 430 PDRQTLL-------FSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGP 482

Query: 315 --------------QSGIIYCFSQK--DSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHR 358
                          SG +  F  K  ++E++  +L+  G + G  H +++  ++  V  
Sbjct: 483 SKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVIS 542

Query: 359 KWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
            +   +I V+VAT     G+D P ++ VI++ +++ ++ +    GR GR
Sbjct: 543 DFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGR 591


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 98/467 (20%), Positives = 182/467 (38%), Gaps = 68/467 (14%)

Query: 10  ELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPA-AW 68
           EL       +    ++  LT  + + +++KK +T +              +    P  A+
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVR------------GGDVCPKPVFAF 173

Query: 69  NKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL 128
           +  +FP    V D+L +    E   P+Q +   + ++G+++  +  TG GK+L Y LPA+
Sbjct: 174 HHANFPQY--VMDVLMDQHFTEP-TPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 129 C----------SDG-FTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEM 177
                       DG   LV+ P   L +    V    G  + + +        K      
Sbjct: 231 VHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRD 290

Query: 178 VNKNSELKLIYVTPEKIAKSKMFMSRLEKAY-EARRFTRIAVDEVHCCSQWGHDFRPDYK 236
           + +  E+ +   TP ++      +  LE      RR T + +DE       G  F P  +
Sbjct: 291 LERGVEICI--ATPGRL------IDFLESGKTNLRRCTYLVLDEADRMLDMG--FEPQIR 340

Query: 237 ALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSN 296
              I+ +  P+   +  +AT    V   A+  L   + +T     N  NL          
Sbjct: 341 K--IVDQIRPDRQTLMWSATWPKEVRQLAEDFL---RDYT---QINVGNLELSANHNILQ 392

Query: 297 TEDFIED------IVKLING--RYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANL 348
             D   +      +++L+      K    II+  +++  + +T  ++  G  A   H   
Sbjct: 393 IVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHG-- 450

Query: 349 EPEDKTTVHRKWSANEIQ-----VVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESG 403
              DK+   R W  NE +     +++AT     G+D  DV+FVI++    S E+Y    G
Sbjct: 451 ---DKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIG 507

Query: 404 RAGRDDMKADCILYYGFGDIFRISSMV-VMENVGQ---QKLYEMVSY 446
           R  R   K     ++  G++ +   ++ V+E   Q    KL ++V +
Sbjct: 508 RTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDH 554


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 98/467 (20%), Positives = 182/467 (38%), Gaps = 68/467 (14%)

Query: 10  ELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPA-AW 68
           EL       +    ++  LT  + + +++KK +T +              +    P  A+
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVR------------GGDVCPKPVFAF 173

Query: 69  NKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL 128
           +  +FP    V D+L +    E   P+Q +   + ++G+++  +  TG GK+L Y LPA+
Sbjct: 174 HHANFPQY--VMDVLMDQHFTEP-TPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 129 C----------SDG-FTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEM 177
                       DG   LV+ P   L +    V    G  + + +        K      
Sbjct: 231 VHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRD 290

Query: 178 VNKNSELKLIYVTPEKIAKSKMFMSRLEKAY-EARRFTRIAVDEVHCCSQWGHDFRPDYK 236
           + +  E+ +   TP ++      +  LE      RR T + +DE       G  F P  +
Sbjct: 291 LERGVEICI--ATPGRL------IDFLESGKTNLRRCTYLVLDEADRMLDMG--FEPQIR 340

Query: 237 ALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSN 296
              I+ +  P+   +  +AT    V   A+  L   + +T     N  NL          
Sbjct: 341 K--IVDQIRPDRQTLMWSATWPKEVRQLAEDFL---RDYT---QINVGNLELSANHNILQ 392

Query: 297 TEDFIED------IVKLING--RYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANL 348
             D   +      +++L+      K    II+  +++  + +T  ++  G  A   H   
Sbjct: 393 IVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHG-- 450

Query: 349 EPEDKTTVHRKWSANEIQ-----VVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESG 403
              DK+   R W  NE +     +++AT     G+D  DV+FVI++    S E+Y    G
Sbjct: 451 ---DKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIG 507

Query: 404 RAGRDDMKADCILYYGFGDIFRISSMV-VMENVGQ---QKLYEMVSY 446
           R  R   K     ++  G++ +   ++ V+E   Q    KL ++V +
Sbjct: 508 RTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDH 554


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 35/120 (29%), Positives = 66/120 (55%), Gaps = 7/120 (5%)

Query: 301 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIH--AGAYHANLEPEDKTTVHR 358
           I D++++ +G ++G++ II+C ++K++++++   QN  I   A + H ++  + +    +
Sbjct: 427 IGDVIRVYSG-HQGRT-IIFCETKKEAQELS---QNSAIKQDAQSLHGDIPQKQREITLK 481

Query: 359 KWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYY 418
            +      V+VAT     G+D P+V  VI  S  K +E+Y   SGR GR      CI +Y
Sbjct: 482 GFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY 541


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 87/416 (20%), Positives = 161/416 (38%), Gaps = 54/416 (12%)

Query: 29  TERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPA--AWNKEDFPWSGKVKDILQNV 86
           + RQ +  Q +K L K   Q   +S +     Y+           DFP S K    LQ  
Sbjct: 28  SHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEA 87

Query: 87  FKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL---------CSDGF-TLV 136
            +      +Q +TI + + GK+V     TG GK+L + +P L          +DG   L+
Sbjct: 88  -QYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLI 146

Query: 137 ICPLISLMEDQLMVLKQLG----ISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPE 192
           I P   L      VL+++G     SA ++      +H     AE +N    + ++  TP 
Sbjct: 147 ISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKH----EAERIN---NINILVCTPG 199

Query: 193 KIAKSKMFMSRLEK--AYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASL 250
           ++      +  +++  ++ A     + +DE       G  F     A  +++        
Sbjct: 200 RL------LQHMDETVSFHATDLQMLVLDEADRILDMG--FADTMNA--VIENLPKKRQT 249

Query: 251 IGLTATATNHV-------LTDAQKILCIEKC-FTFTASFNRPNLYYEVRQKPSNTEDFIE 302
           +  +AT T  V       L + + +   EK  ++  A+  +  +  E++QK S    F+ 
Sbjct: 250 LLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLR 309

Query: 303 DIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNL--GIHAGAYHANLEPEDKTTVHRKW 360
             +K        +  I++  S K+ + +      L  G+   A H   +   +  V+ ++
Sbjct: 310 SHLK--------KKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361

Query: 361 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCIL 416
                 V+ AT     G+D P V +V+     +    Y   +GR  R     + +L
Sbjct: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALL 417


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 72/352 (20%), Positives = 147/352 (41%), Gaps = 48/352 (13%)

Query: 81  DILQNVFK--LEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVIC 138
           D+L+++ +  + K  P+Q +   + + G ++ +V  TG GK+L Y +P     GF  +  
Sbjct: 232 DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP-----GFIHLDS 286

Query: 139 PLISLMEDQ---LMVLKQLGISATMLNASSSKEHVKWVHAEMV----NKNSELK------ 185
             IS  +     ++VL      A  + A  SK   K + +  +    N+N +++      
Sbjct: 287 QPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGV 346

Query: 186 -LIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQ 244
            +I  TP ++   +M       +   R  T + +DE         +F P  + + +  R 
Sbjct: 347 DIIIATPGRLNDLQM-----NNSVNLRSITYLVIDEAD--KMLDMEFEPQIRKILLDVR- 398

Query: 245 FPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN-------RPNLYYEV-RQKPSN 296
            P+   +  +AT  + V   A   L  +    +  + N       + N+     ++K + 
Sbjct: 399 -PDRQTVMTSATWPDTVRQLALSYLK-DPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRAL 456

Query: 297 TEDFIEDIVKLINGRYKGQSGIIYCFSQKD-SEQVTVSLQNLGIHAGAYHANLEPEDKTT 355
           T++F+E++             +I   SQK  ++ ++      GI A + H N E  D+  
Sbjct: 457 TQEFVENM--------SPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQER 508

Query: 356 VHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
               + +  I++++ T     G+D  DV  V ++   ++++ Y    G  GR
Sbjct: 509 AVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGR 560


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 80/399 (20%), Positives = 159/399 (39%), Gaps = 37/399 (9%)

Query: 89  LEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDG------FTLVICPLIS 142
           L++  P+QL  I   + G++      TG GK+  + LP L          F LV+ P   
Sbjct: 22  LKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRE 81

Query: 143 L---MEDQLMVL-KQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSK 198
           L   + +Q  VL K LG+   ++           + A+ +  + +  ++  TP ++A   
Sbjct: 82  LAYQIAEQFRVLGKPLGLKDCIIVGGMD------MVAQALELSRKPHVVIATPGRLADHL 135

Query: 199 MFMSRLEKAYEARRFTRIAVDEVHCCSQWG-HDFRPDYKALGILKRQFPNASLIGLTATA 257
               R    +  ++   + +DE     + G  DF  D +A+           L   T T 
Sbjct: 136 ----RSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTD 191

Query: 258 TNHVLTDAQKILCIEKCFTFTASF---NRPNLYYEVRQKPSNTED-FIEDIVKLINGRYK 313
           T   L      L   + F + A         L       P   +D ++  +++     ++
Sbjct: 192 TLRELQG----LATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHE 247

Query: 314 GQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVA 373
             S II+  + K  + + + L+       A H+ ++ +++     K+ ++  ++++AT  
Sbjct: 248 DWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDV 307

Query: 374 FGMGIDKPDVRFVIHHSMSKSMENYYQESG---RAGRDDMKADCILYYGFGDIFRISSMV 430
              G+D P V+ VI+H+     + Y    G   RAGR       +  Y    +  I   +
Sbjct: 308 ASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQI 367

Query: 431 VME----NVGQQKLYEMVSYCQNISK-CRRVLMAQHFDE 464
             +    +V + ++ ++++    + + C   L A HFDE
Sbjct: 368 KKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDE 406


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 65/336 (19%), Positives = 136/336 (40%), Gaps = 34/336 (10%)

Query: 90  EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL--------CSDGFTLVICPLI 141
           EK  P+Q + I   M+G+++  +  TG GK++ + LP            +G   +   + 
Sbjct: 393 EKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMT 452

Query: 142 SLMEDQLMVLKQ-------LGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKI 194
              E  L + K+       LG+    +   +       +  ++       ++I  TP ++
Sbjct: 453 PTRELALQITKECKKFSKTLGLRVVCVYGGTG------ISEQIAELKRGAEIIVCTPGRM 506

Query: 195 AKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLT 254
               M  +   +    RR T + +DE       G  F P  + + I+    P+   +  +
Sbjct: 507 ID--MLAANSGRVTNLRRVTYVVLDEADRMFDMG--FEP--QVMRIVDNVRPDRQTVMFS 560

Query: 255 ATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTED---FIEDIVKLINGR 311
           AT    +   A++IL   K         R  +  +V Q+    E+   F++ +++L+   
Sbjct: 561 ATFPRAMEALARRIL--SKPIEVQVG-GRSVVCSDVEQQVIVIEEEKKFLK-LLELLGHY 616

Query: 312 YKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVAT 371
            +  S II+   Q+ ++ +   L        + H  ++  D+ ++   +     +++VAT
Sbjct: 617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVAT 676

Query: 372 VAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
                G+D   +  V+++S     E+Y   +GR GR
Sbjct: 677 SVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGR 712


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 77/392 (19%), Positives = 158/392 (40%), Gaps = 45/392 (11%)

Query: 81  DILQNVFK--LEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVIC 138
           ++++N+ K   +K  P+Q +   + + G ++  V  TG GK+LCY +P        LV+ 
Sbjct: 252 EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIH----LVLQ 307

Query: 139 PLISLMEDQ--LMVLKQLGISATMLNASSSKEHVKWVHAEMV----NKNSELK------- 185
           P +    ++  ++VL      A  +     K   K + +  V    N++ +++       
Sbjct: 308 PSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVD 367

Query: 186 LIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQF 245
           +I  TP ++   +M           +  T + +DE       G  F P  + + IL    
Sbjct: 368 IIIATPGRLNDLQM-----SNFVNLKNITYLVLDEADKMLDMG--FEP--QIMKILLDVR 418

Query: 246 PNASLIGLTATATNHVLTDAQK------ILCIEKCFTFTASFNRPNLYYEVRQ-KPSNTE 298
           P+   +  +AT  + V   AQ       I+ +        S  + N+     + K S+ +
Sbjct: 419 PDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQ 478

Query: 299 DFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHR 358
            F++ +             I++   +  ++ ++  L    I   + H + E  D+     
Sbjct: 479 TFLQSMSST-------DKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALE 531

Query: 359 KWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYY 418
            +   ++++++AT     G+D  DV  V +    +++E Y    GR GR       I   
Sbjct: 532 NFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTL 591

Query: 419 GFGDIFRISSMV--VMENVGQQKLYEMVSYCQ 448
              D +R++S +  ++E   Q    E+VS  +
Sbjct: 592 TRND-WRVASELINILERANQSIPEELVSMAE 622


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 312 YKGQSG--IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVV 369
           Y G  G  II+C ++K+  ++ ++  ++  +A   H ++    +    + +     +V+V
Sbjct: 385 YSGSEGRAIIFCETKKNVTEMAMN-PHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLV 443

Query: 370 ATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYY 418
           AT     G+D P+V  VI  S  + +E+Y   SGR GR      CI +Y
Sbjct: 444 ATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFY 492


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/90 (31%), Positives = 45/90 (50%)

Query: 318 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 377
           II+   +K  + +  SL+ +G +A   H     E +        A    ++VAT   G G
Sbjct: 668 IIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRG 727

Query: 378 IDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
           ID  DV  V+++ M+K++E+Y    GR GR
Sbjct: 728 IDIQDVSMVVNYDMAKNIEDYIHRIGRTGR 757


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 75/368 (20%), Positives = 136/368 (36%), Gaps = 41/368 (11%)

Query: 80  KDILQNVFKL--EKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL-----CSDG 132
           +++L  +F++  EK  P+Q E+I + ++G+++      G GKS  Y +P L       D 
Sbjct: 105 RELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDN 164

Query: 133 F-TLVICPL--ISLMEDQLMVLKQLGISATMLNASSSKEHVK--------WVHAEMVNKN 181
              +VI P   ++L   Q+ +     +    + A++   +++         VH  +    
Sbjct: 165 IQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPG 224

Query: 182 SELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGIL 241
             L LI     K+   +M +        ++ F +I  D +           P  + + + 
Sbjct: 225 RILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTL--------PKNRQILLY 276

Query: 242 KRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFI 301
              FP    + +     +H+    +  L  E        +     Y   RQK        
Sbjct: 277 SATFP----LSVQKFMNSHLQKPYEINLMEELTLKGVTQYYA---YVTERQKVH------ 323

Query: 302 EDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWS 361
              +  +  R +    II+C S +  E +   +  LG      HA +  E +  V   + 
Sbjct: 324 --CLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFR 381

Query: 362 ANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFG 421
               + +V T  F  GID   V  VI+    K  E Y    GR+GR       I    + 
Sbjct: 382 NGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYD 441

Query: 422 DIFRISSM 429
           D F + S+
Sbjct: 442 DRFNLKSI 449


>gi|110556640 DNA helicase HEL308 [Homo sapiens]
          Length = 1101

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 82/401 (20%), Positives = 144/401 (35%), Gaps = 83/401 (20%)

Query: 78  KVKDILQNVFKLEKFRPLQLE--TINVTMAGKEVFLVMPTGGGKSLCYQL----PALCSD 131
           KV+D+      +EK    Q    T+N     K +   +PT GGK+L  ++      LC  
Sbjct: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381

Query: 132 GFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTP 191
              L+I P ++++++++  L   GI          +E+          K  E K +Y+  
Sbjct: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFF----VEEYAGSKGRFPPTKRREKKSLYIA- 436

Query: 192 EKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLI 251
             I K    ++ L +         + VDE+H   +       +     IL        +I
Sbjct: 437 -TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTS-KTTQII 494

Query: 252 GLTATATNHVLTDAQKILCIEKCFTFTASFNRPNL---------YYEVRQKPSNTEDFI- 301
           G++AT  N  + D QK L  E    +T+ F    L          YEV  K  N   F  
Sbjct: 495 GMSATLNN--VEDLQKFLQAE---YYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSR 549

Query: 302 ---------------EDIVKLINGRYKGQSGIIYCFSQKDSE------------------ 328
                          + +V L+       S +++C S+K+ E                  
Sbjct: 550 LLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHK 609

Query: 329 -----QVTVSLQNLG-------------IHAGAYHANLEPEDKTTVHRKWSANEIQVVVA 370
                +V  +L+N+G                  +H+ L  +++  +   +S   + +   
Sbjct: 610 EKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTC 669

Query: 371 TVAFGMGIDKPDVRFVIHHS-MSKSM---ENYYQESGRAGR 407
           T     G++ P  R ++    ++K       Y Q  GRAGR
Sbjct: 670 TSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGR 710


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 26/90 (28%), Positives = 45/90 (50%)

Query: 318 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 377
           +I+   + D + +   L   G+ A A H   + E++T     +   +  V+VAT     G
Sbjct: 436 LIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKG 495

Query: 378 IDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
           +D P ++ VI++ M + +ENY    GR GR
Sbjct: 496 LDFPAIQHVINYDMPEEIENYVHRIGRTGR 525



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 11/35 (31%), Positives = 23/35 (65%)

Query: 94  PLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPAL 128
           P+Q++ I   ++G+++  +  TG GK+L + LP +
Sbjct: 206 PIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 1/118 (0%)

Query: 290 VRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLE 349
           +R +P N E   E IV  +  R      +++  ++K + ++ + L  +G+  G  H NL 
Sbjct: 440 IRIRP-NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLS 498

Query: 350 PEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
              +    R++   +I ++VAT     G+D   V+ VI+ +M  ++++Y    GR  R
Sbjct: 499 QTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/106 (19%), Positives = 55/106 (51%)

Query: 318 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 377
           +I+C +++  + +T  ++       + H ++  +++ ++ +++ +   +V+++T  +  G
Sbjct: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340

Query: 378 IDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDI 423
           +D P V  +I++ +  + E Y    GR+GR   K   I +    DI
Sbjct: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI 386


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 73/341 (21%), Positives = 133/341 (39%), Gaps = 42/341 (12%)

Query: 95  LQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCS------DGFTLVICPLISL---ME 145
           +Q+E I + + G+++  +  TG GK+  + LP L +        F LV+ P   L   + 
Sbjct: 50  IQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQIS 109

Query: 146 DQLMVL-KQLGISATML-----NASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKM 199
           +Q   L   +G+ + ++     + S S    K  H           +I  TP ++     
Sbjct: 110 EQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPH-----------IIIATPGRL----- 153

Query: 200 FMSRLE--KAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATA 257
            +  LE  K +  R    + +DE         +   D K L ++ R   +      +AT 
Sbjct: 154 -IDHLENTKGFNLRALKYLVMDEADRILNMDFETEVD-KILKVIPR---DRKTFLFSATM 208

Query: 258 TNHVLTDAQKILCIE-KCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQS 316
           T  V    +  L    KC   +       L       PS  +D    +V ++N    G S
Sbjct: 209 TKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTY--LVYILN-ELAGNS 265

Query: 317 GIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGM 376
            +I+C +  ++++  + L+NLG  A   H  +    +     K+ A    +++AT     
Sbjct: 266 FMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASR 325

Query: 377 GIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILY 417
           G+D P V  V++  +    ++Y    GR  R       I +
Sbjct: 326 GLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITF 366


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 24/118 (20%), Positives = 56/118 (47%)

Query: 313 KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATV 372
           K    I++  +++  +++T  ++  G  A   H +   +++  V  ++   +  +++AT 
Sbjct: 340 KENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATD 399

Query: 373 AFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMV 430
               G+D  DV+FVI++    S E+Y    GR  R         ++   +I ++S ++
Sbjct: 400 VASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLI 457


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 22/98 (22%), Positives = 47/98 (47%)

Query: 318 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 377
           +I+  +++  + +T  +        A H +++ +++  + R++ +   +V++ T     G
Sbjct: 276 VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 335

Query: 378 IDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCI 415
           ID   V  VI++ +  + ENY    GR GR   K   I
Sbjct: 336 IDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAI 373


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 22/98 (22%), Positives = 47/98 (47%)

Query: 318 IIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMG 377
           +I+  +++  + +T  +        A H +++ +++  + R++ +   +V++ T     G
Sbjct: 277 VIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 336

Query: 378 IDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCI 415
           ID   V  VI++ +  + ENY    GR GR   K   I
Sbjct: 337 IDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAI 374


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,742,153
Number of Sequences: 37866
Number of extensions: 976027
Number of successful extensions: 3830
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 3650
Number of HSP's gapped (non-prelim): 173
length of query: 649
length of database: 18,247,518
effective HSP length: 109
effective length of query: 540
effective length of database: 14,120,124
effective search space: 7624866960
effective search space used: 7624866960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.