Guide to the Human Genome
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Name: DGAT1 Sequence: fasta or formatted (488aa) NCBI GI: 145864459
Description:

diacylglycerol O-acyltransferase 1

Referenced in:

Bile Acids and Other Cholesterol Derivatives
Lipid Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.1         54           3
 C cysteine            1.6          8           1
 D aspartate           3.7         18           1
 E glutamate           3.5         17           3
 F phenylalanine       6.4         31           2
 G glycine             6.1         30           4
 H histidine           2.5         12           1
 I isoleucine          4.7         23           2
 K lysine              3.1         15           2
 L leucine            11.7         57           3
 M methionine          2.9         14           2
 N asparagine          3.9         19           1
 P proline             5.3         26           1
 Q glutamine           2.9         14           2
 R arginine            7.0         34           4
 S serine              6.8         33           2
 T threonine           2.7         13           1
 V valine              7.0         34           2
 W tryptophan          3.3         16           2
 Y tyrosine            4.1         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   diacylglycerol O-acyltransferase 1 
SOAT2                 0.111   acyl-CoA:cholesterol acyltransferase 2 
SOAT1                 0.100   sterol O-acyltransferase 1 
TAF4                  0.015   TBP-associated factor 4 
OSBP                  0.011   oxysterol binding protein 
LMO2                  0.011   LIM domain only 2 isoform 1 
LOC100293776          0.010   PREDICTED: hypothetical protein 
LOC100288658          0.010   PREDICTED: hypothetical protein XP_002342750 
LOC100288658          0.010   PREDICTED: hypothetical protein 
EN1                   0.010   engrailed homeobox 1 
TWIST1                0.010   twist 
TRIM67                0.009   tripartite motif-containing 67 
DMKN                  0.008   dermokine isoform 4 precursor 
DMKN                  0.008   dermokine isoform 2 precursor 
LOC100290263          0.008   PREDICTED: hypothetical protein XP_002347916 
HOXC12                0.008   homeobox C12 
MEX3D                 0.008   ring finger and KH domain containing 1 
IP6K1                 0.007   inositol hexakisphosphate kinase 1 isoform 1 
SCAMP4                0.007   secretory carrier membrane protein 4 
SLC12A6               0.007   solute carrier family 12, member 6 isoform e 
SLC12A6               0.007   solute carrier family 12, member 6 isoform d 
SLC12A6               0.007   solute carrier family 12, member 6 isoform c 
SLC12A6               0.007   solute carrier family 12, member 6 isoform c 
SLC12A6               0.007   solute carrier family 12, member 6 isoform b 
SLC12A6               0.007   solute carrier family 12, member 6 isoform a 
LOC100291383          0.006   PREDICTED: hypothetical protein XP_002346891 
MLL2                  0.006   myeloid/lymphoid or mixed-lineage leukemia 2 
CRMP1                 0.006   collapsin response mediator protein 1 isoform 1 [Hom...
DMKN                  0.006   dermokine isoform 6 
CRY2                  0.005   cryptochrome 2 (photolyase-like) isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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