Guide to the Human Genome
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Search of human proteins with 145312270

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
         (561 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145312259 tudor and KH domain containing isoform a [Homo sapi...  1114   0.0  
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...  1114   0.0  
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...  1114   0.0  
gi|145312246 tudor and KH domain containing isoform b [Homo sapi...   868   0.0  
gi|38505161 tudor domain containing 1 [Homo sapiens]                   89   8e-18
gi|40255178 tudor domain containing 5 [Homo sapiens]                   84   4e-16
gi|112293287 tudor domain containing 7 [Homo sapiens]                  82   2e-15
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    74   5e-13
gi|17402900 far upstream element-binding protein [Homo sapiens]        73   6e-13
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ...    72   2e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]          71   2e-12
gi|94421471 ring finger protein 17 [Homo sapiens]                      70   7e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        66   7e-11
gi|58197558 tudor domain containing 6 [Homo sapiens]                   65   2e-10
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          64   4e-10
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ...    63   6e-10
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    61   2e-09
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ...    61   2e-09
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    61   2e-09
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho...    60   7e-09
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho...    60   7e-09
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho...    60   7e-09
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1...    59   2e-08
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ...    59   2e-08
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]       58   3e-08
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]       58   3e-08
gi|166851804 tudor domain containing 9 [Homo sapiens]                  57   4e-08
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                 57   6e-08
gi|4885409 high density lipoprotein binding protein [Homo sapiens]     55   1e-07
gi|42716280 high density lipoprotein binding protein [Homo sapiens]    55   1e-07

>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 1114 bits (2881), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
           MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60

Query: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
           QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120

Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
           ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180

Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
           KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240

Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
           SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300

Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
           SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360

Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
           AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420

Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
           LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480

Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
           DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540

Query: 541 LSLSEAASMSGDDNLEDDYLL 561
           LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 1114 bits (2881), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
           MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60

Query: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
           QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120

Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
           ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180

Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
           KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240

Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
           SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300

Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
           SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360

Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
           AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420

Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
           LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480

Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
           DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540

Query: 541 LSLSEAASMSGDDNLEDDYLL 561
           LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 1114 bits (2881), Expect = 0.0
 Identities = 561/561 (100%), Positives = 561/561 (100%)

Query: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
           MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60

Query: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
           QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120

Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
           ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180

Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
           KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240

Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
           SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300

Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
           SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360

Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
           AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420

Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
           LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480

Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
           DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540

Query: 541 LSLSEAASMSGDDNLEDDYLL 561
           LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561


>gi|145312246 tudor and KH domain containing isoform b [Homo
           sapiens]
          Length = 516

 Score =  868 bits (2242), Expect = 0.0
 Identities = 463/563 (82%), Positives = 475/563 (84%), Gaps = 49/563 (8%)

Query: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
           MSTERTSWTSLSTIQKIALGLGIPASATVAYIL   YR  RE                  
Sbjct: 1   MSTERTSWTSLSTIQKIALGLGIPASATVAYIL---YRRYRES----------------- 40

Query: 61  QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
           +E     +G     I+                V  E V LI G      +  A I Q+  
Sbjct: 41  REERLTFVGEDDIEIEMR--------------VPQEAVKLIIG------RQGANIKQLRK 80

Query: 121 ENTPVSEQLSVPQRSVG--RIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
           +      ++ V    VG  R++   G  ++    ASGAKITCDKESEGTLLLSRLIKISG
Sbjct: 81  QT---GARIDVDTEDVGDERVLLISGFPVQ----ASGAKITCDKESEGTLLLSRLIKISG 133

Query: 179 TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK 238
           TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK
Sbjct: 134 TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK 193

Query: 239 NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP 298
           NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP
Sbjct: 194 NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP 253

Query: 299 DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD 358
           DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD
Sbjct: 254 DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD 313

Query: 359 IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE 418
           IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE
Sbjct: 314 IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE 373

Query: 419 CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK 478
           CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK
Sbjct: 374 CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK 433

Query: 479 KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL 538
           KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL
Sbjct: 434 KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL 493

Query: 539 SCLSLSEAASMSGDDNLEDDYLL 561
           SCLSLSEAASMSGDDNLEDDYLL
Sbjct: 494 SCLSLSEAASMSGDDNLEDDYLL 516


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)

Query: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
           D+ ++V V     P  F+  ++   +L+ L+ L   + +H +  +P      +G    A 
Sbjct: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772

Query: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
              +GSWYRA V   L NG++ ++FVD+G+  +    +LR + S FL+LPFQ I C LA 
Sbjct: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832

Query: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 463
           I      W EEA+  F     C     L A++    + GI
Sbjct: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)

Query: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 363
           DE+  V V+  + P  F+ Q + S   +L +L   ++++ +   P  D    +GDI  A 
Sbjct: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551

Query: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
              +  WYRA VL      ++ + +VD+G+     L  L  +    L LP QAI+C LA 
Sbjct: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611

Query: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 483
           + PS   W  EA+    +L      K +  K+   ++        + L D S    + + 
Sbjct: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664

Query: 484 LELVHKGYAI-------ELPEDIEE 501
             L+  G+A+       + P D++E
Sbjct: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)

Query: 356  VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
            +GD   A   ++  WYRA VLGT +  ++++ + D+G+    PL  ++ + S  L+LPFQ
Sbjct: 993  IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051

Query: 416  AIECSL 421
             I CSL
Sbjct: 1052 IIRCSL 1057



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)

Query: 312 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 370
           V+  +HP  F++Q+  S  L+ +++L   + + Y N   +D     G++  A    + +W
Sbjct: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329

Query: 371 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
            RA +    ++     + ++D+G+    PL  +  L  +    P  AI+C +A + P+  
Sbjct: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389

Query: 430 QWEEEAL 436
            W  + +
Sbjct: 390 NWSSDCI 396


>gi|40255178 tudor domain containing 5 [Homo sapiens]
          Length = 981

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)

Query: 286 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 344
           A+P   +  +P  D S     ++E  +S    P+ F+I+I    S +L + ++ EM + Y
Sbjct: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510

Query: 345 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 398
            N +  D  V        G +    +  +  WYR  +   LE   +++++ DFG+ G   
Sbjct: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570

Query: 399 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 458
              LR L+  +  LP QAI CSLA + P  + W  +A+ +F +L      KPLV  +  Y
Sbjct: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627

Query: 459 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 499
           V  GI     I+L DTS+ + +     L  +G+AI   E+I
Sbjct: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664


>gi|112293287 tudor domain containing 7 [Homo sapiens]
          Length = 1098

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)

Query: 254  PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 313
            P    G+M +  +   ++ K   D  +KS           E+P P       E+++VYV 
Sbjct: 860  PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919

Query: 314  ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 373
             + HP +F IQ       +L+ L+ EM  +Y  S    + V    + AA +     W+R 
Sbjct: 920  VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976

Query: 374  RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
             + G L NG + +Y +D+G +    ++ ++ L   F  LPFQA+   LA +    +QW E
Sbjct: 977  LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034

Query: 434  EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 475
            EA   F    +  + KPLVA + + ++   + W +   +YL DTS
Sbjct: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)

Query: 292 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 351
           M +I  P      +    V V    + N   I+ VG       +L+ +  + Y +  P+ 
Sbjct: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508

Query: 352 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 408
                V+VG ++A     + +W RA+V+ T EN  + + +VD+G + +        L   
Sbjct: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566

Query: 409 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 468
           F SL FQA +C LA +    D  + + +   + LT          KI +      +  P 
Sbjct: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616

Query: 469 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 528
           + LYDTS    ++I    +               +A+ D   ++  + DA  + +     
Sbjct: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661

Query: 529 KSSGEITHTLSCLSLSEAASM 549
            S G +   + C  L++ + +
Sbjct: 662 CSDGTLYCQVPCKGLNKLSDL 682



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)

Query: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 423
           G W R  +     +  LD+ F+D G      + +LR +   FL    ++P QAI+C LA 
Sbjct: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775

Query: 424 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 476
           +  S   W  +A L   D + +C+D    V K+      GI+    +YL+   N
Sbjct: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 13/157 (8%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
           E +VP + V  IIGR G  I +++ ++G +I + +E  G  ER  +++G P  + +AK  
Sbjct: 81  EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140

Query: 115 IHQILT------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
           + QI+             ++    +++ +P   VG +IGRGGETI+ + + +G K+   +
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200

Query: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
           +        + ++I+G   +V  A+ ++LE + E ++
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 21/163 (12%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED---VGDERVLLISGFPVQVCKAK 112
           E+ +P   V L+IGR G  IKQL+++TG ++ +  +     G ++ L I+G   +V +A+
Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAR 225

Query: 113 AAIHQILTENTPV----------------SEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
             + +I+ E                    S ++SVP+ +VG +IGR GE I+ I   +G 
Sbjct: 226 EMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGV 285

Query: 157 KITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
           +I   K  +G +   R  ++ G       A H+I E +   +E
Sbjct: 286 RIQF-KPDDG-ISPERAAQVMGPPDRCQHAAHIISELILTAQE 326



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 36/173 (20%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
           IE+ VP+ AV ++IGR G  IK+++   G RI    +D +  ER   + G P +   A  
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAH 315

Query: 114 AIHQIL-------------------------TENTPVSEQ---LSVPQRSVGRIIGRGGE 145
            I +++                         +   P   Q    +VP    G +IG+GGE
Sbjct: 316 IISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGE 375

Query: 146 TIRSICKASGAKITCDK----ESEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
            I+SI + SGA +   +     S+  L   R   I G  +++  A+ LI EKV
Sbjct: 376 NIKSINQQSGAHVELQRNPPPNSDPNL---RRFTIRGVPQQIEVARQLIDEKV 425



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 6/78 (7%)

Query: 113 AAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
           A +HQ     T ++E+  VP + VG IIGRGGE I  I   SG KI    ES G  +  R
Sbjct: 70  ALVHQ----RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSG--IPER 123

Query: 173 LIKISGTQKEVAAAKHLI 190
              ++GT + +  AK L+
Sbjct: 124 PCVLTGTPESIEQAKRLL 141



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)

Query: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE----RVLLISGFPVQVC 109
           EI   VP +   L+IG+ G NIK + +Q+GA +++      +     R   I G P Q+ 
Sbjct: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIE 415

Query: 110 KAKAAIHQ 117
            A+  I +
Sbjct: 416 VARQLIDE 423


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
           E +VP   V  IIGR G  I ++++++G +I +  +  G  ER  +++G P  V  AK  
Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRL 163

Query: 115 IHQILTENTPVS------------EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
           + QI+ +  P              +++ +P    G +IG+GGETI+ + + +G K+   +
Sbjct: 164 LDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQ 223

Query: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
           +        + ++I+G   +V  AK ++LE + +    R+
Sbjct: 224 DGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFRE 263



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 33/189 (17%)

Query: 37  YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGD 95
           +RE R E  + +G ++  I++ +P+ AV ++IGR G  IK+++   G RI    +D    
Sbjct: 261 FREVRNEYGSRIGGNE-GIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319

Query: 96  ERVLLISGFPVQVCKAKAAIHQILTENTPVSE---------------------------- 127
           ER+  I+G P   C+  A I   L  +                                 
Sbjct: 320 ERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQE 378

Query: 128 -QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLS-RLIKISGTQKEVAA 185
               VP    G IIG+GGETI+SI + SGA+I   +        + +L  I GT +++  
Sbjct: 379 FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDY 438

Query: 186 AKHLILEKV 194
           A+ LI EK+
Sbjct: 439 ARQLIEEKI 447



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 20/155 (12%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFPVQVCKAK 112
           E+ +P     L+IG+ G  IKQL+++ G +   I    ++ G ++ L I+G P +V +AK
Sbjct: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAK 248

Query: 113 AAIHQILTENTPVSE---------------QLSVPQRSVGRIIGRGGETIRSICKASGAK 157
             + +++ +     E                + +P+ +VG +IGR GE I+ I   +G +
Sbjct: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308

Query: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE 192
           I   K  +GT    R+ +I+G       A  +I +
Sbjct: 309 IQF-KPDDGT-TPERIAQITGPPDRCQHAAEIITD 341



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)

Query: 125 VSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVA 184
           ++E+  VP   VG IIGRGGE I  I + SG KI    +S G  L  R   ++GT + V 
Sbjct: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGG--LPERSCMLTGTPESVQ 158

Query: 185 AAKHLI 190
           +AK L+
Sbjct: 159 SAKRLL 164


>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 56/192 (29%), Positives = 91/192 (47%), Gaps = 35/192 (18%)

Query: 39  ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
           E+   + T  GED    +++ +P  A   IIG+ G  I QL+K+TGA I +    D    
Sbjct: 35  EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94

Query: 94  GDERVLLISGFPVQVCKAKAAIHQILTENT-----------PVS---------------E 127
             ERV LI G      +A  A+H  + E             PVS                
Sbjct: 95  TTERVCLIQG----TVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
           ++ VP  + G IIG+GG T++++ + SGA +   ++ +G  L  R++ +SG  ++   A 
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210

Query: 188 HLILEKVSEDEE 199
            LI++K+ ED +
Sbjct: 211 ELIIQKIQEDPQ 222



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
           +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R + I+GT     
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458

Query: 185 AAKHLILEKVSEDEELR 201
           AA++LI ++++ ++ +R
Sbjct: 459 AAQYLITQRITYEQGVR 475



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 46  TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101
           T V  D I ++++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +
Sbjct: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199

Query: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136
           SG P Q  KA   I Q + E+      L++   +V
Sbjct: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
           G  D+ +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G 
Sbjct: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453

Query: 105 PVQVCKAKAAIHQILT 120
           P     A+  I Q +T
Sbjct: 454 PAATQAAQYLITQRIT 469


>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 34/180 (18%)

Query: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFP 105
           E +  +++ +P  A   IIG+ G  I QL+K+TGA I +    D      ERV L+ G  
Sbjct: 30  EGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQG-- 87

Query: 106 VQVCKAKAAIHQILTENTPVSEQ--------------------------LSVPQRSVGRI 139
               +A  A+H  + E      Q                          L VP  + G I
Sbjct: 88  --TAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLI 145

Query: 140 IGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
           IG+GG T++++ + SGA +   ++ EG  L  R++ +SG  ++V  A   I++KV ED +
Sbjct: 146 IGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
           + ++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +SG P QV K
Sbjct: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHK 191

Query: 111 AKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGET 146
           A +AI Q + E+   S  L++   +V   +     T
Sbjct: 192 AVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPT 227



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)

Query: 117 QILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRL 173
           ++  E+     +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R 
Sbjct: 399 KLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT--RNRR 456

Query: 174 IKISGTQKEVAAAKHLILEKVSEDEELR 201
           + I+G+     AA++LI ++V+ ++ +R
Sbjct: 457 VTITGSPAATQAAQYLISQRVTYEQGVR 484



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGFPVQVCK 110
           +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G P     
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468

Query: 111 AKAAIHQILTENTPVSEQLSVPQR 134
           A+  I Q +T    V  + S PQ+
Sbjct: 469 AQYLISQRVTYEQGV--RASNPQK 490


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)

Query: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 365
           + V V     P  F++Q++    L +  L+  + + Y++   E+L +   V D       
Sbjct: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737

Query: 366 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
            +G WYRA+V+G   +  +++ +VDFG+     +KD+R ++ +FL+ P +AI+C LA I 
Sbjct: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797

Query: 426 P--SGDQWEEEALDEFD 440
           P     QW +EA ++F+
Sbjct: 798 PYKRTMQWSKEAKEKFE 814



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)

Query: 271  WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 330
            W+ PS +    +E   +  +    +P+ +F    ++ L V++     P   ++Q + + +
Sbjct: 882  WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940

Query: 331  LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 390
            L L+ L  +M   YENS  E +        A  +     W R +++  + +  +++   D
Sbjct: 941  L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999

Query: 391  FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 444
             G     N DC    LR L  +  ++   ++ECSL  I P+G  D+W   A D    L  
Sbjct: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054

Query: 445  CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 493
                  ++ ++ S  +   +TWP   KI+  D   G+++D+   L+ KG A+
Sbjct: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 370  WYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
            WYR +V+  +  G + + ++D G     P   L  +   +  +P   I C L    P G+
Sbjct: 1244 WYRGKVMEVV-GGAVRVQYLDHGFTEKIPQCHLYPILL-YPDIPQFCIPCQLHNTTPVGN 1301

Query: 430  QWEEEALDEFDRL 442
             W+ +A++   +L
Sbjct: 1302 VWQPDAIEVLQQL 1314


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 27/185 (14%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
           E RVP   V LIIGR G  I ++++ +G ++ +  +  G  ER + ++G P  V KAK  
Sbjct: 148 EYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMM 207

Query: 115 IHQILT-----------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAK 157
           +  I++                 +N  V E + +P    G +IG+GGETI+ + + +G K
Sbjct: 208 LDDIVSRGRGGPPGQFHDNANGGQNGTVQE-IMIPAGKAGLVIGKGGETIKQLQERAGVK 266

Query: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDE--------ELRKRIAHSAE 209
           +   ++      + + ++I G   +V  A  ++++ + E +        E   RI    +
Sbjct: 267 MILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGID 326

Query: 210 TRVPR 214
             VPR
Sbjct: 327 VPVPR 331



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 33/172 (19%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
           I++ VP+ +V ++IGR G  IK+++   G RI    +D  G E++  I G P +   A  
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR 384

Query: 114 AIHQILTE----------------------------NTPVSEQ-LSVPQRSVGRIIGRGG 144
            I+ +L                                P  E   S+P    G +IGRGG
Sbjct: 385 IINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG 444

Query: 145 ETIRSICKASGAKITCDKE--SEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
           E +++I + +GA +   ++    G     +L  I G+ +++  AK LI EK+
Sbjct: 445 ENVKAINQQTGAFVEISRQLPPNGDPNF-KLFIIRGSPQQIDHAKQLIEEKI 495



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 18/136 (13%)

Query: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFP 105
           G++    E+ +P     L+IG+ G  IKQL+++ G +   I   +++   ++ L I G P
Sbjct: 230 GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP 289

Query: 106 VQVCKAKAAIHQILTENTPVSE--------------QLSVPQRSVGRIIGRGGETIRSIC 151
            +V +A   +  IL E                     + VP+ SVG +IGR GE I+ I 
Sbjct: 290 YKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQ 349

Query: 152 KASGAKITCDKESEGT 167
             +G +I   K+ +GT
Sbjct: 350 NDAGVRIQF-KQDDGT 364



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)

Query: 123 TPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKE 182
           T ++E+  VP   VG IIGRGGE I  I + SG K+    +S G  L  R + ++G  + 
Sbjct: 143 TSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGG--LPERSVSLTGAPES 200

Query: 183 VAAAKHLILEKVS 195
           V  AK ++ + VS
Sbjct: 201 VQKAKMMLDDIVS 213



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 4/68 (5%)

Query: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTE--DVGDE--RVLLISGFPVQVC 109
           E+   +P     L+IGR G N+K + +QTGA +++  +    GD   ++ +I G P Q+ 
Sbjct: 426 EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQID 485

Query: 110 KAKAAIHQ 117
            AK  I +
Sbjct: 486 HAKQLIEE 493


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)

Query: 264 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 320
           V+  + + E+  + S  +S A+ + E    EI  P         + + +  V   ++P+ 
Sbjct: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501

Query: 321 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 377
           FWI++    ++   KL+  M   Y ++   D   L     D+       NG +YRA ++ 
Sbjct: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558

Query: 378 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 437
            L++ ++D++ VD G++ +    D+R L   F  LP  A++C+LA I P G  W +EA+ 
Sbjct: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618

Query: 438 EFDR 441
            F +
Sbjct: 619 FFKK 622



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)

Query: 308 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 364
           +EV VS  E+P +FW Q+  +R++Q L  L++++  + +N+       H  + +A  A  
Sbjct: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827

Query: 365 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 423
             N  W RA + G     ++++ FVD+GD     +K++ ++  +FL +  QA  CSL   
Sbjct: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887

Query: 424 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 464
           I P G     W+ +A+  F+     A  K L  K + +    I+
Sbjct: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)

Query: 308  LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 363
            +  Y +  + P +FW Q   +  LQ  ++      E      N +P     ++GD     
Sbjct: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577

Query: 364  LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 422
               +G +YRA +    E+  + +  VDFG+  DC   K L A+ S+ LS+P QA  C L+
Sbjct: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637

Query: 423  RIAPSGDQWEEEALDEF 439
                S     +E  D F
Sbjct: 1638 GFNISEGLCSQEGNDYF 1654



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)

Query: 310  VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
            VY++  + P  F+ Q+  + ++  QL   + ++++   N     L  + G +  A   T+
Sbjct: 990  VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046

Query: 368  GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 424
            G+WYR  V+   E     ++FVDFG+       DL  + SD    L LP QA+ CSL+ I
Sbjct: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)

Query: 310  VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
            VYVS     + F++Q++   +    L + +N +    E  V   L    GD++ A  P +
Sbjct: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366

Query: 368  GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
              WYRA +     N  L + F+D+G+        +  L      LP   I CSL
Sbjct: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)

Query: 367 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
           +G WYRA +L T        +  VD+G         LR L  ++  +P     C+L  + 
Sbjct: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382

Query: 426 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 485
             G  W    + +   L      K + AKI  Y       +  +Y  D  N  ++  G++
Sbjct: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438

Query: 486 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 521
                  +   +  EE        +  A E D  +S
Sbjct: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 10/82 (12%)

Query: 370 WYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG- 428
           W+R RV+      +  ++ +D G         L   R +F +LP + + C LA + P+G 
Sbjct: 81  WHRCRVVSRQAQESR-VFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLAGLVPAGC 139

Query: 429 --------DQWEEEALDEFDRL 442
                     W  +A+D    L
Sbjct: 140 GAGSGEPPQHWPADAVDFLSNL 161


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 14/147 (9%)

Query: 349 PEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGN-LDLYFVDFGDNGDCPLKDLRALRS 407
           P ++TV    I AAP   +G+W+RA+V+ + E  N +++ +VD+G      +  LR +RS
Sbjct: 758 PVEITV----ICAAP-GADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRS 812

Query: 408 DFLSLPFQAIECSLARIAP--SGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGIST 465
           DF++LPFQ  E  L  + P    DQ+  EA      +T       L+A+++SY  TG+  
Sbjct: 813 DFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNT---ALLAQVTSYSPTGL-- 867

Query: 466 WPKIYLYDTSNGKKLDIGLELVHKGYA 492
            P I L+     + + I   LV +G A
Sbjct: 868 -PLIQLWSVVGDEVVLINRSLVERGLA 893



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIK---ISGTQKEVA 184
           ++ VP+  VGR+IG+ G  +  + + SGAKI        TL  ++ ++   I G+Q  V 
Sbjct: 611 EIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYI-----STLPYTQSVQICHIEGSQHHVD 665

Query: 185 AAKHLILEKVSE 196
            A +LI +K  E
Sbjct: 666 KALNLIGKKFKE 677



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 9/63 (14%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
           E+ VP+  V  +IG+QG  +  L++ +GA+I + T         L     VQ+C  + + 
Sbjct: 611 EIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYIST---------LPYTQSVQICHIEGSQ 661

Query: 116 HQI 118
           H +
Sbjct: 662 HHV 664


>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
           sapiens]
          Length = 507

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/212 (26%), Positives = 93/212 (43%), Gaps = 51/212 (24%)

Query: 39  ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
           E+   + T  GED    +++ +P  A   IIG+ G  I QL+K+TGA I +    D    
Sbjct: 35  EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94

Query: 94  GDERVLLISG------------------FPVQVCKAKAA-------------IHQIL--- 119
             ERV LI G                   P  V K +               I Q L   
Sbjct: 95  TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSS 154

Query: 120 ---TENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGT 167
              T+++P            ++ VP  + G IIG+GG T++++ + SGA +   ++ +G 
Sbjct: 155 PTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI 214

Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
            L  R++ +SG  ++   A  LI++K+ ED +
Sbjct: 215 NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQ 246



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 47/235 (20%)

Query: 73  ANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT-ENTPVSEQLSV 131
           A I+Q    TG  ID+D  D            P++      +  +  T E+     ++ +
Sbjct: 5   APIQQNGTHTGVPIDLDPPDSRKR--------PLEAPPEAGSTKRTNTGEDGQYFLKVLI 56

Query: 132 PQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVAAAKH 188
           P  + G IIG+GG+TI  + K +GA I   K  +   GT    R+  I GT + + A   
Sbjct: 57  PSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT--TERVCLIQGTVEALNAVHG 114

Query: 189 LILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMT-EPGGAGEPALWKNTSSSMEPT 247
            I EK+ E  +            V + +P+S+ +   T  P    +      T++   P+
Sbjct: 115 FIAEKIREMPQ-----------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPS 163

Query: 248 APLVTPPP-----------------KGGGDMAVVVSKEGSW----EKPSDDSFQK 281
            P+ T                    KGG  +  V+ + G+W    +KP   + Q+
Sbjct: 164 DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQE 218



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
           +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R + I+GT     
Sbjct: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 482

Query: 185 AAKHLILEKVSEDEELR 201
           AA++LI ++++ ++ +R
Sbjct: 483 AAQYLITQRITYEQGVR 499



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)

Query: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
           ++++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +SG P Q  K
Sbjct: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232

Query: 111 AKAAIHQILTENTPVSEQLSVPQRSV 136
           A   I Q + E+      L++   +V
Sbjct: 233 AVELIIQKIQEDPQSGSCLNISYANV 258



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
           G  D+ +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G 
Sbjct: 419 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 477

Query: 105 PVQVCKAKAAIHQILT 120
           P     A+  I Q +T
Sbjct: 478 PAATQAAQYLITQRIT 493


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
           + + +P +AV  IIG++GA+IKQL +  GA I +   +  D  ER+++I+G P    KA+
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446

Query: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
             I   L         E   +   + VP  + GR+IG+GG+T+  +   + A++   ++ 
Sbjct: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 506

Query: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
              E   ++ R+I      +        I+++V + E+
Sbjct: 507 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)

Query: 52  DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
           D  + + VP + V  IIG++G  IK + KQT +R+D+  ++     E+ + I   P    
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252

Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
           + C+    I Q   + T ++E++ +        VGR+IG+ G  ++ I   +G KIT   
Sbjct: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312

Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
             + ++    R I + GT +  A+A+  I++K+ E
Sbjct: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 47/223 (21%)

Query: 32  ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
           IL    +E+ E +L     ++I +++      V  +IG++G N+K++  +TG +I +   
Sbjct: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313

Query: 89  -DTEDVGDERVLLISGFPVQVCKA----------KAAIHQILTENT-------------- 123
            D      ER + + G  V+ C +          +A  + +L  NT              
Sbjct: 314 QDLSIYNPERTITVKG-TVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQF 372

Query: 124 ---------PVSE--QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
                    P  E   L +P ++VG IIG+ G  I+ + + +GA I     +EG  +  R
Sbjct: 373 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSER 431

Query: 173 LIKISGTQKEVAAAKHLILEKVSEDE--ELRKRIAHSAETRVP 213
           ++ I+G  +    A+  I  K+ E+     ++ +   A  RVP
Sbjct: 432 MVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVP 474



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
           E  +E  +RVP      +IG+ G  + +L+  T A + V    T D  +E ++ I G   
Sbjct: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523

Query: 107 QVCKAKAAIHQILTE 121
               A+  I +I+ +
Sbjct: 524 ASQTAQRKIREIVQQ 538


>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
           isoform a [Homo sapiens]
          Length = 599

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
           + + +P +AV  IIG++GA+IKQL +  GA I +   +  D  ER+++I+G P    KA+
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489

Query: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
             I   L         E   +   + VP  + GR+IG+GG+T+  +   + A++   ++ 
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549

Query: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
              E   ++ R+I      +        I+++V + E+
Sbjct: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)

Query: 52  DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
           D  + + VP + V  IIG++G  IK + KQT +R+D+  ++     E+ + I   P    
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252

Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
           + C+    I Q   + T ++E++ +        VGR+IG+ G  ++ I   +G KIT   
Sbjct: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312

Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
             + ++    R I + GT +  A+A+  I++K+ E
Sbjct: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 8/94 (8%)

Query: 32  ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
           IL    +E+ E +L     ++I +++      V  +IG++G N+K++  +TG +I +   
Sbjct: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313

Query: 89  -DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
            D      ER + + G       A+  I + L E
Sbjct: 314 QDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
           E  +E  +RVP      +IG+ G  + +L+  T A + V    T D  +E ++ I G   
Sbjct: 507 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 566

Query: 107 QVCKAKAAIHQILTE 121
               A+  I +I+ +
Sbjct: 567 ASQTAQRKIREIVQQ 581


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE--RVLLISGFPVQVCKAK 112
           + + +P  +V  IIG+QG +IKQL +  GA I +   +  D   R+++I+G P    KA+
Sbjct: 408 VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQ 467

Query: 113 AAIHQILTENTPVSEQ--------LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKES 164
             I+  + E   VS +        + VP  + GR+IG+GG+T+  +   S A++   ++ 
Sbjct: 468 GRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQ 527

Query: 165 EGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIA 205
                   ++KI+G       A+  I E +++ ++ +++ A
Sbjct: 528 TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKA 568



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 14/160 (8%)

Query: 52  DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFPVQVC 109
           D+ + + VP + V  IIG++GA I+ + KQT ++IDV   E+ G  E+ + I   P    
Sbjct: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254

Query: 110 KAKAAIHQIL---------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
            A  +I +I+         TE  P+  ++      VGR+IG+ G  ++ I + +  KIT 
Sbjct: 255 AACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITI 312

Query: 161 DKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
               E TL    R I + G  +  A A+  I++K+ E  E
Sbjct: 313 SPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYE 352



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)

Query: 35  RRYRESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DT 90
           R Y + +EE      E+  +E  +RVP  A   +IG+ G  + +L+  + A + V    T
Sbjct: 469 RIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQT 528

Query: 91  EDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
            D  D+ V+ I+G       A+  I +ILT+
Sbjct: 529 PDENDQVVVKITGHFYACQVAQRKIQEILTQ 559



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 50/247 (20%), Positives = 96/247 (38%), Gaps = 64/247 (25%)

Query: 26  SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
           SA    IL   ++E+++ + T    ++I +++      V  +IG++G N+K++ + T  +
Sbjct: 254 SAACKSILEIMHKEAQDIKFT----EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK 309

Query: 86  IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTEN------------------- 122
           I +    +      ER + + G      KA+  I + + E+                   
Sbjct: 310 ITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369

Query: 123 ------------------------TPVSEQ----------LSVPQRSVGRIIGRGGETIR 148
                                   TP   Q          L +P  SVG IIG+ G+ I+
Sbjct: 370 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIK 429

Query: 149 SICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL--RKRIAH 206
            + + +GA I     +E      R++ I+G  +    A+  I  K+ E+  +  ++ +  
Sbjct: 430 QLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKL 488

Query: 207 SAETRVP 213
            A  RVP
Sbjct: 489 EAHIRVP 495


>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)

Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
           +P++FW++    R+ +  +++  + + Y+    +++ +     G    A    +  +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697

Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
            V+  +    +++YF+D+G+    P  D++ L  +F  LP  A+ CSLA I P  D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756

Query: 434 EALDEFDRL 442
            A+D F +L
Sbjct: 757 AAIDYFKKL 765



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)

Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
           V VS++  P+ F+ Q++   + +L+ L   MT HY+    E   T     ++      NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
            W+R  +   L    + ++F+D+G +   P   ++ L+ DF+ +P  +  CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)

Query: 294  EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
            ++P P    +A   ++ YVS   +P +F IQ+  + S  ++L   +N   +       + 
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486

Query: 352  LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
            +   VGD+V A    + + YRA +   L   + ++ F+D+G++       +  L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546

Query: 412  LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
            +P   I   L+ +      + W+++ +D F    H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)

Query: 296  PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
            P  ++ F     LEV  S    P  F  Q+   +S  L  L+ ++  +Y  S+  D    
Sbjct: 892  PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947

Query: 356  VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
            +G   A     +G W RA VL T  +  +D+ FVD+G      ++DL A+   FL L  Q
Sbjct: 948  IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005

Query: 416  AIECSL 421
            A  C L
Sbjct: 1006 AFRCCL 1011



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)

Query: 309  EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
            EVY+S    P  F+ Q+ G  +  L+ +  ++T+            +   +  +    +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172

Query: 369  SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
              YRA  + T  +    +YFVDFG+    G+  L+ + A   + L  P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)

Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
           FQ  E +  P+    ++ S  F      +L+V ++ S     P    ++  G +S + + 
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187

Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
             + + +  +++      V + +        +G W R RV+   +N    +  +D G+  
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246

Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
                 + +   +   LP + +    A I P G++W  +AL+ F  L        +  ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298

Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
             YVQ  +     ++       + L++ L  +  G +  L  ++ E   + +PD+L+   
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358

Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
            E       L    K +S +I H L  L  S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382


>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)

Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
           +P++FW++    R+ +  +++  + + Y+    +++ +     G    A    +  +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697

Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
            V+  +    +++YF+D+G+    P  D++ L  +F  LP  A+ CSLA I P  D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756

Query: 434 EALDEFDRL 442
            A+D F +L
Sbjct: 757 AAIDYFKKL 765



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)

Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
           V VS++  P+ F+ Q++   + +L+ L   MT HY+    E   T     ++      NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
            W+R  +   L    + ++F+D+G +   P   ++ L+ DF+ +P  +  CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)

Query: 294  EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
            ++P P    +A   ++ YVS   +P +F IQ+  + S  ++L   +N   +       + 
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486

Query: 352  LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
            +   VGD+V A    + + YRA +   L   + ++ F+D+G++       +  L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546

Query: 412  LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
            +P   I   L+ +      + W+++ +D F    H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)

Query: 296  PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
            P  ++ F     LEV  S    P  F  Q+   +S  L  L+ ++  +Y  S+  D    
Sbjct: 892  PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947

Query: 356  VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
            +G   A     +G W RA VL T  +  +D+ FVD+G      ++DL A+   FL L  Q
Sbjct: 948  IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005

Query: 416  AIECSL 421
            A  C L
Sbjct: 1006 AFRCCL 1011



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)

Query: 309  EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
            EVY+S    P  F+ Q+ G  +  L+ +  ++T+            +   +  +    +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172

Query: 369  SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
              YRA  + T  +    +YFVDFG+    G+  L+ + A   + L  P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)

Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
           FQ  E +  P+    ++ S  F      +L+V ++ S     P    ++  G +S + + 
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187

Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
             + + +  +++      V + +        +G W R RV+   +N    +  +D G+  
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246

Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
                 + +   +   LP + +    A I P G++W  +AL+ F  L        +  ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298

Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
             YVQ  +     ++       + L++ L  +  G +  L  ++ E   + +PD+L+   
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358

Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
            E       L    K +S +I H L  L  S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382


>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)

Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
           +P++FW++    R+ +  +++  + + Y+    +++ +     G    A    +  +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697

Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
            V+  +    +++YF+D+G+    P  D++ L  +F  LP  A+ CSLA I P  D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756

Query: 434 EALDEFDRL 442
            A+D F +L
Sbjct: 757 AAIDYFKKL 765



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)

Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
           V VS++  P+ F+ Q++   + +L+ L   MT HY+    E   T     ++      NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449

Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
            W+R  +   L    + ++F+D+G +   P   ++ L+ DF+ +P  +  CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)

Query: 294  EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
            ++P P    +A   ++ YVS   +P +F IQ+  + S  ++L   +N   +       + 
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486

Query: 352  LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
            +   VGD+V A    + + YRA +   L   + ++ F+D+G++       +  L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546

Query: 412  LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
            +P   I   L+ +      + W+++ +D F    H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)

Query: 296  PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
            P  ++ F     LEV  S    P  F  Q+   +S  L  L+ ++  +Y  S+  D    
Sbjct: 892  PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947

Query: 356  VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
            +G   A     +G W RA VL T  +  +D+ FVD+G      ++DL A+   FL L  Q
Sbjct: 948  IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005

Query: 416  AIECSL 421
            A  C L
Sbjct: 1006 AFRCCL 1011



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)

Query: 309  EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
            EVY+S    P  F+ Q+ G  +  L+ +  ++T+            +   +  +    +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172

Query: 369  SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
              YRA  + T  +    +YFVDFG+    G+  L+ + A   + L  P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)

Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
           FQ  E +  P+    ++ S  F      +L+V ++ S     P    ++  G +S + + 
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187

Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
             + + +  +++      V + +        +G W R RV+   +N    +  +D G+  
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246

Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
                 + +   +   LP + +    A I P G++W  +AL+ F  L        +  ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298

Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
             YVQ  +     ++       + L++ L  +  G +  L  ++ E   + +PD+L+   
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358

Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
            E       L    K +S +I H L  L  S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382


>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
           isoform 2 [Homo sapiens]
          Length = 438

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)

Query: 24  PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
           P S+      Y  + ++ E+ +         +++ +P +AV  IIG++G +IKQL +   
Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 297

Query: 84  ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
           A I +   +  D   R+++I+G P    KA+  I+  L         E   +   + VP 
Sbjct: 298 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 357

Query: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
            + GR+IG+GG+T+  +   + A++   ++         ++KI G
Sbjct: 358 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 402



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 51  DDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFPV 106
           D++ +++      V  +IG++G N+K++ + T  +I +    D      ER + + G   
Sbjct: 136 DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE 195

Query: 107 QVCKAKAAIHQILTE 121
             C+A+  I + + E
Sbjct: 196 NCCRAEQEIMKKVRE 210



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 136 VGRIIGRGGETIRSICKASGAKITCDKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKV 194
           VGR+IG+ G  ++ + + +  KIT     + TL    R I + G  +    A+  I++KV
Sbjct: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208

Query: 195 SEDEE 199
            E  E
Sbjct: 209 REAYE 213


>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
           isoform 1 [Homo sapiens]
          Length = 577

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)

Query: 24  PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
           P S+      Y  + ++ E+ +         +++ +P +AV  IIG++G +IKQL +   
Sbjct: 386 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 436

Query: 84  ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
           A I +   +  D   R+++I+G P    KA+  I+  L         E   +   + VP 
Sbjct: 437 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 496

Query: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
            + GR+IG+GG+T+  +   + A++   ++         ++KI G
Sbjct: 497 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 541



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 10/158 (6%)

Query: 52  DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFP---V 106
           DI + + VP + V  IIG++GA I+ + KQT ++IDV   E+ G  E+ + +   P    
Sbjct: 195 DIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCS 254

Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
             CK    I     ++T  ++++ +        VGR+IG+ G  ++ + + +  KIT   
Sbjct: 255 SACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS 314

Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
             + TL    R I + G  +    A+  I++KV E  E
Sbjct: 315 LQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 8/100 (8%)

Query: 26  SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
           S+    IL   ++E+++ +      D++ +++      V  +IG++G N+K++ + T  +
Sbjct: 254 SSACKMILEIMHKEAKDTKTA----DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309

Query: 86  IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
           I +    D      ER + + G     C+A+  I + + E
Sbjct: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)

Query: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
           + I + +  + V  IIG++G  +K++R+++GARI++ +E    ER++ I+G    + KA 
Sbjct: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104

Query: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
           A I             +   T   PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163

Query: 160 CDKESEGTLL---LSRLIKISGT 179
              +  G +L     R + ISGT
Sbjct: 164 ---QVAGDMLPNSTERAVTISGT 183



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 68/211 (32%)

Query: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISGFP----- 105
           + + + VP      +IG+ G+ IK++R+ TGA++ V  D      ER + ISG P     
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189

Query: 106 --VQVCKAK-----------------AAIHQILTENTPV--------------------- 125
              Q+C                      +HQ+  + TP                      
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249

Query: 126 -------------------SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEG 166
                              + +L++P   +G IIGR G  I  I + SGA+I     +EG
Sbjct: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309

Query: 167 TLLLSRLIKISGTQKEVAAAKHLILEKVSED 197
           +    R I I+GT   ++ A++LI  +++ +
Sbjct: 310 S--SERQITITGTPANISLAQYLINARLTSE 338



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
           N  ++ +L +  + VG IIG+ GET++ + + SGA+I     SEG     R++ I+G   
Sbjct: 43  NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98

Query: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
            +  A  +I  K  ED  +   +++S  T  P   P+++R
Sbjct: 99  AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133


>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)

Query: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
           + I + +  + V  IIG++G  +K++R+++GARI++ +E    ER++ I+G    + KA 
Sbjct: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104

Query: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
           A I             +   T   PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163

Query: 160 CDKESEGTLL---LSRLIKISGT 179
              +  G +L     R + ISGT
Sbjct: 164 ---QVAGDMLPNSTERAVTISGT 183



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
           E+ +P + +  IIGRQG  I ++R+ +GA+I +     G  ER + I+G P  +  A+  
Sbjct: 297 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYL 356

Query: 115 IHQILT 120
           I+  LT
Sbjct: 357 INARLT 362



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 2/72 (2%)

Query: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
           + +L++P   +G IIGR G  I  I + SGA+I     +EG+    R I I+GT   ++ 
Sbjct: 295 THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISL 352

Query: 186 AKHLILEKVSED 197
           A++LI  +++ +
Sbjct: 353 AQYLINARLTSE 364



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
           N  ++ +L +  + VG IIG+ GET++ + + SGA+I     SEG     R++ I+G   
Sbjct: 43  NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98

Query: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
            +  A  +I  K  ED  +   +++S  T  P   P+++R
Sbjct: 99  AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)

Query: 305  DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
            D  L + V+      HFW  +I  + S  L KL  E+ Q     VP     H   +  AP
Sbjct: 897  DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954

Query: 364  LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
                    ++RA+VL    N + +++FVD+G+     L  L  +   FL LPFQA+E  +
Sbjct: 955  FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013

Query: 422  ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 475
             ++ PS      G  W + A   F  L        L+ K+ S V + +     +Y Y + 
Sbjct: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067

Query: 476  NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 529
                ++I   L+ +GYA EL E+  E++   ++LK + ++     TD S+   + + +K
Sbjct: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 21/147 (14%)

Query: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
           + I + +  + V  IIG++G ++K++R+++GARI++ +E    ER++ ++G        F
Sbjct: 14  LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI-SEGNCPERIITLTGPTNAIFKAF 72

Query: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
            + + K +  I+  +T +T     PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 73  AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV- 131

Query: 160 CDKESEGTLL---LSRLIKISGTQKEV 183
              +  G +L     R I I+G  + V
Sbjct: 132 ---QVAGDMLPNSTERAITIAGVPQSV 155



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 2/80 (2%)

Query: 119 LTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
           L  +T  + +L++P   +G IIGR G  I  I + SGA+I      EG+    R + I+G
Sbjct: 274 LDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITG 331

Query: 179 TQKEVAAAKHLILEKVSEDE 198
           +   ++ A++LI  ++S ++
Sbjct: 332 SAASISLAQYLINARLSSEK 351



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
           N  ++ +L +  + VG IIG+ GE+++ I + SGA+I     SEG     R+I ++G   
Sbjct: 11  NVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGN-CPERIITLTGPTN 66

Query: 182 EVAAAKHLILEKVSED 197
            +  A  +I++K+ ED
Sbjct: 67  AIFKAFAMIIDKLEED 82



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%)

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE-RVLLISGFPVQVCKAKAA 114
           E+ +P   +  IIGRQGANI ++R+ +GA+I +     G   R + I+G    +  A+  
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYL 342

Query: 115 IHQILT 120
           I+  L+
Sbjct: 343 INARLS 348



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 8/108 (7%)

Query: 46  TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
           T      + + + VP      +IG+ G  IK++R+ TGA++ V  D      ER + I+G
Sbjct: 91  TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150

Query: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV------PQRSVGRIIGRGGE 145
            P  V +    I  ++ E    S Q  V      P  +   +I  GG+
Sbjct: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ 198


>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)

Query: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
           E+   I + + ++  K IIG+ GANIK++R+++  +ID+  E+   E  ++I+G      
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637

Query: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
            A++ I  I  +   ++E ++S+P +    +IG  G  IRSI  +  G  I    E  G 
Sbjct: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696

Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
              S  + I G   +V  AK  +L    E +
Sbjct: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 53   IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
            + IE+ VP +  + +IG++G+ I+++  +    I V   ++  + ++ I+G    + +AK
Sbjct: 973  VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031

Query: 113  AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
            A + + + E     E          ++V  +   +IIGR G  I  I       I    +
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091

Query: 164  SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
             +G     + I I+G +K   AA+  IL  V E E++
Sbjct: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)

Query: 39  ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
           E  +++L  + E+       +++R   E  K +IG+ G  I+++R  TGAR+     +  
Sbjct: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769

Query: 95  DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
           D+ ++ I G    V +A+  +  ++   +  V + + V  +     + R G+ +R I + 
Sbjct: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829

Query: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
            G  +     S GT   S  + + G +  V AAK  I E +   E+L  ++  + E  +P
Sbjct: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881

Query: 214 RK 215
           +K
Sbjct: 882 QK 883



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)

Query: 67   IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
            IIGR+GA I Q+R +    I    +D G++    + I+G+      A+ AI +I+ E   
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126

Query: 124  PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
             VSE + +  R   RIIG  G+ IR I       I   +           + ++G  + V
Sbjct: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183

Query: 184  AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
              A   IL   + +EE    +  S   +V  K P     E+   P  G     A W  +S
Sbjct: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237

Query: 242  SSMEPTAPLVTPPPKGGGDMA 262
            S   P        P  G  +A
Sbjct: 1238 SEKAPDMSSSEEFPSFGAQVA 1258



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)

Query: 69  GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
           G Q     ++ ++TGA +++   +D G    +++SG    V KA+  I  +    T  S 
Sbjct: 98  GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
            +++P+     +IG+ GE ++ +   +  KI   +  +     S  IKI+GT++ +  A+
Sbjct: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209

Query: 188 HLILEKVSEDEE 199
           H +L   +E ++
Sbjct: 210 HEVLLISAEQDK 221



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
           +E+ +  +  + +IG+ GANI +++ Q     RI  D+E      ++ I G P  V +AK
Sbjct: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494

Query: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
             + ++ +      ++ L + QR    IIG+ GE IR I
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)

Query: 37  YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
           Y E +++  T      I +E++  Q   K +IG +G +++++ ++TG  +++   D   E
Sbjct: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339

Query: 97  RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
            V+L  G P ++ +A   ++     N+     ++ P      IIG+ G+ +  I
Sbjct: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)

Query: 59  VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
           +P+E  + +IG+ G  ++ L  +T  +I +   D    ++  I+G    + KA+  +  I
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215

Query: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
             E +    E+L V +     I G     +  I + +G +I     S     ++R   + 
Sbjct: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270

Query: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
             +KE  A     ++K+ E+++ +         +   K  I  +   + E       ++ 
Sbjct: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330

Query: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
              S S+  T  L   P K G  +  V +K  S+
Sbjct: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364


>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)

Query: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
           E+   I + + ++  K IIG+ GANIK++R+++  +ID+  E+   E  ++I+G      
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637

Query: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
            A++ I  I  +   ++E ++S+P +    +IG  G  IRSI  +  G  I    E  G 
Sbjct: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696

Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
              S  + I G   +V  AK  +L    E +
Sbjct: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 53   IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
            + IE+ VP +  + +IG++G+ I+++  +    I V   ++  + ++ I+G    + +AK
Sbjct: 973  VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031

Query: 113  AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
            A + + + E     E          ++V  +   +IIGR G  I  I       I    +
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091

Query: 164  SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
             +G     + I I+G +K   AA+  IL  V E E++
Sbjct: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)

Query: 39  ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
           E  +++L  + E+       +++R   E  K +IG+ G  I+++R  TGAR+     +  
Sbjct: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769

Query: 95  DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
           D+ ++ I G    V +A+  +  ++   +  V + + V  +     + R G+ +R I + 
Sbjct: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829

Query: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
            G  +     S GT   S  + + G +  V AAK  I E +   E+L  ++  + E  +P
Sbjct: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881

Query: 214 RK 215
           +K
Sbjct: 882 QK 883



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)

Query: 67   IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
            IIGR+GA I Q+R +    I    +D G++    + I+G+      A+ AI +I+ E   
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126

Query: 124  PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
             VSE + +  R   RIIG  G+ IR I       I   +           + ++G  + V
Sbjct: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183

Query: 184  AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
              A   IL   + +EE    +  S   +V  K P     E+   P  G     A W  +S
Sbjct: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237

Query: 242  SSMEPTAPLVTPPPKGGGDMA 262
            S   P        P  G  +A
Sbjct: 1238 SEKAPDMSSSEEFPSFGAQVA 1258



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)

Query: 69  GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
           G Q     ++ ++TGA +++   +D G    +++SG    V KA+  I  +    T  S 
Sbjct: 98  GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153

Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
            +++P+     +IG+ GE ++ +   +  KI   +  +     S  IKI+GT++ +  A+
Sbjct: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209

Query: 188 HLILEKVSEDEE 199
           H +L   +E ++
Sbjct: 210 HEVLLISAEQDK 221



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
           +E+ +  +  + +IG+ GANI +++ Q     RI  D+E      ++ I G P  V +AK
Sbjct: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494

Query: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
             + ++ +      ++ L + QR    IIG+ GE IR I
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)

Query: 37  YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
           Y E +++  T      I +E++  Q   K +IG +G +++++ ++TG  +++   D   E
Sbjct: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339

Query: 97  RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
            V+L  G P ++ +A   ++     N+     ++ P      IIG+ G+ +  I
Sbjct: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)

Query: 59  VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
           +P+E  + +IG+ G  ++ L  +T  +I +   D    ++  I+G    + KA+  +  I
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215

Query: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
             E +    E+L V +     I G     +  I + +G +I     S     ++R   + 
Sbjct: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270

Query: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
             +KE  A     ++K+ E+++ +         +   K  I  +   + E       ++ 
Sbjct: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330

Query: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
              S S+  T  L   P K G  +  V +K  S+
Sbjct: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,866,317
Number of Sequences: 37866
Number of extensions: 1052996
Number of successful extensions: 3121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2794
Number of HSP's gapped (non-prelim): 271
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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