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Search of human proteins with 145312259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
(561 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 1114 0.0
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 1114 0.0
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 1114 0.0
gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 868 0.0
gi|38505161 tudor domain containing 1 [Homo sapiens] 89 8e-18
gi|40255178 tudor domain containing 5 [Homo sapiens] 84 4e-16
gi|112293287 tudor domain containing 7 [Homo sapiens] 82 2e-15
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 74 5e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 73 6e-13
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 72 2e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 71 2e-12
gi|94421471 ring finger protein 17 [Homo sapiens] 70 7e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 66 7e-11
gi|58197558 tudor domain containing 6 [Homo sapiens] 65 2e-10
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] 64 4e-10
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 63 6e-10
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 61 2e-09
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 61 2e-09
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 61 2e-09
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho... 60 7e-09
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho... 60 7e-09
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho... 60 7e-09
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 59 2e-08
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 59 2e-08
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 58 3e-08
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 58 3e-08
gi|166851804 tudor domain containing 9 [Homo sapiens] 57 4e-08
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 57 6e-08
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 55 1e-07
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 55 1e-07
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 1114 bits (2881), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
Query: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
Query: 541 LSLSEAASMSGDDNLEDDYLL 561
LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 1114 bits (2881), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
Query: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
Query: 541 LSLSEAASMSGDDNLEDDYLL 561
LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 1114 bits (2881), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP
Sbjct: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
Query: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT
Sbjct: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
Query: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ
Sbjct: 121 ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQ 180
Query: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT
Sbjct: 181 KEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNT 240
Query: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF
Sbjct: 241 SSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDF 300
Query: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV
Sbjct: 301 SFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIV 360
Query: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS
Sbjct: 361 AAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECS 420
Query: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL
Sbjct: 421 LARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKL 480
Query: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC
Sbjct: 481 DIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSC 540
Query: 541 LSLSEAASMSGDDNLEDDYLL 561
LSLSEAASMSGDDNLEDDYLL
Sbjct: 541 LSLSEAASMSGDDNLEDDYLL 561
>gi|145312246 tudor and KH domain containing isoform b [Homo
sapiens]
Length = 516
Score = 868 bits (2242), Expect = 0.0
Identities = 463/563 (82%), Positives = 475/563 (84%), Gaps = 49/563 (8%)
Query: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVP 60
MSTERTSWTSLSTIQKIALGLGIPASATVAYIL YR RE
Sbjct: 1 MSTERTSWTSLSTIQKIALGLGIPASATVAYIL---YRRYRES----------------- 40
Query: 61 QEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT 120
+E +G I+ V E V LI G + A I Q+
Sbjct: 41 REERLTFVGEDDIEIEMR--------------VPQEAVKLIIG------RQGANIKQLRK 80
Query: 121 ENTPVSEQLSVPQRSVG--RIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
+ ++ V VG R++ G ++ ASGAKITCDKESEGTLLLSRLIKISG
Sbjct: 81 QT---GARIDVDTEDVGDERVLLISGFPVQ----ASGAKITCDKESEGTLLLSRLIKISG 133
Query: 179 TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK 238
TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK
Sbjct: 134 TQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWK 193
Query: 239 NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP 298
NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP
Sbjct: 194 NTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP 253
Query: 299 DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD 358
DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD
Sbjct: 254 DFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGD 313
Query: 359 IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE 418
IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE
Sbjct: 314 IVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIE 373
Query: 419 CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK 478
CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK
Sbjct: 374 CSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGK 433
Query: 479 KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL 538
KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL
Sbjct: 434 KLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTL 493
Query: 539 SCLSLSEAASMSGDDNLEDDYLL 561
SCLSLSEAASMSGDDNLEDDYLL
Sbjct: 494 SCLSLSEAASMSGDDNLEDDYLL 516
>gi|38505161 tudor domain containing 1 [Homo sapiens]
Length = 1189
Score = 89.4 bits (220), Expect = 8e-18
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
Query: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
D+ ++V V P F+ ++ +L+ L+ L + +H + +P +G A
Sbjct: 713 DQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAF 772
Query: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
+GSWYRA V L NG++ ++FVD+G+ + +LR + S FL+LPFQ I C LA
Sbjct: 773 FAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLAD 832
Query: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGI 463
I W EEA+ F C L A++ + GI
Sbjct: 833 IQSRNKHWSEEAITRFQM---CVAGIKLQARVVEVTENGI 869
Score = 57.4 bits (137), Expect = 3e-08
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 17/205 (8%)
Query: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPE-DLTVHVGDIVAAP 363
DE+ V V+ + P F+ Q + S +L +L ++++ + P D +GDI A
Sbjct: 494 DEFCGV-VAHIQTPEDFFCQQLQS-GRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQ 551
Query: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR 423
+ WYRA VL ++ + +VD+G+ L L + L LP QAI+C LA
Sbjct: 552 FSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAG 611
Query: 424 IAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIG 483
+ PS W EA+ +L K + K+ ++ + L D S + +
Sbjct: 612 VKPSLGIWTPEAICLMKKLVQN---KIITVKVVDKLENS----SLVELIDKSETPHVSVS 664
Query: 484 LELVHKGYAI-------ELPEDIEE 501
L+ G+A+ + P D++E
Sbjct: 665 KVLLDAGFAVGEQSMVTDKPSDVKE 689
Score = 50.1 bits (118), Expect = 5e-06
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
+GD A ++ WYRA VLGT + ++++ + D+G+ PL ++ + S L+LPFQ
Sbjct: 993 IGDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQ 1051
Query: 416 AIECSL 421
I CSL
Sbjct: 1052 IIRCSL 1057
Score = 49.3 bits (116), Expect = 9e-06
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Query: 312 VSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSW 370
V+ +HP F++Q+ S L+ +++L + + Y N +D G++ A + +W
Sbjct: 270 VTEFKHPGDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQTW 329
Query: 371 YRARVLGT-LENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
RA + ++ + ++D+G+ PL + L + P AI+C +A + P+
Sbjct: 330 NRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG 389
Query: 430 QWEEEAL 436
W + +
Sbjct: 390 NWSSDCI 396
>gi|40255178 tudor domain containing 5 [Homo sapiens]
Length = 981
Score = 83.6 bits (205), Expect = 4e-16
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)
Query: 286 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 344
A+P + +P D S ++E +S P+ F+I+I S +L + ++ EM + Y
Sbjct: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510
Query: 345 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 398
N + D V G + + + WYR + LE +++++ DFG+ G
Sbjct: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570
Query: 399 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 458
LR L+ + LP QAI CSLA + P + W +A+ +F +L KPLV + Y
Sbjct: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627
Query: 459 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 499
V GI I+L DTS+ + + L +G+AI E+I
Sbjct: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 81.6 bits (200), Expect = 2e-15
Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)
Query: 254 PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 313
P G+M + + ++ K D +KS E+P P E+++VYV
Sbjct: 860 PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919
Query: 314 ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 373
+ HP +F IQ +L+ L+ EM +Y S + V + AA + W+R
Sbjct: 920 VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976
Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
+ G L NG + +Y +D+G + ++ ++ L F LPFQA+ LA + +QW E
Sbjct: 977 LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034
Query: 434 EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 475
EA F + + KPLVA + + ++ + W + +YL DTS
Sbjct: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)
Query: 292 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 351
M +I P + V V + N I+ VG +L+ + + Y + P+
Sbjct: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508
Query: 352 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 408
V+VG ++A + +W RA+V+ T EN + + +VD+G + + L
Sbjct: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566
Query: 409 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 468
F SL FQA +C LA + D + + + + LT KI + + P
Sbjct: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616
Query: 469 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 528
+ LYDTS ++I + +A+ D ++ + DA + +
Sbjct: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661
Query: 529 KSSGEITHTLSCLSLSEAASM 549
S G + + C L++ + +
Sbjct: 662 CSDGTLYCQVPCKGLNKLSDL 682
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 423
G W R + + LD+ F+D G + +LR + FL ++P QAI+C LA
Sbjct: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775
Query: 424 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 476
+ S W +A L D + +C+D V K+ GI+ +YL+ N
Sbjct: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 73.6 bits (179), Expect = 5e-13
Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 13/157 (8%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
E +VP + V IIGR G I +++ ++G +I + +E G ER +++G P + +AK
Sbjct: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRL 140
Query: 115 IHQILT------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
+ QI+ ++ +++ +P VG +IGRGGETI+ + + +G K+ +
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQ 200
Query: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
+ + ++I+G +V A+ ++LE + E ++
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQ 237
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED---VGDERVLLISGFPVQVCKAK 112
E+ +P V L+IGR G IKQL+++TG ++ + + G ++ L I+G +V +A+
Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAR 225
Query: 113 AAIHQILTENTPV----------------SEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
+ +I+ E S ++SVP+ +VG +IGR GE I+ I +G
Sbjct: 226 EMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGV 285
Query: 157 KITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
+I K +G + R ++ G A H+I E + +E
Sbjct: 286 RIQF-KPDDG-ISPERAAQVMGPPDRCQHAAHIISELILTAQE 326
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 36/173 (20%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
IE+ VP+ AV ++IGR G IK+++ G RI +D + ER + G P + A
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAH 315
Query: 114 AIHQIL-------------------------TENTPVSEQ---LSVPQRSVGRIIGRGGE 145
I +++ + P Q +VP G +IG+GGE
Sbjct: 316 IISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGE 375
Query: 146 TIRSICKASGAKITCDK----ESEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
I+SI + SGA + + S+ L R I G +++ A+ LI EKV
Sbjct: 376 NIKSINQQSGAHVELQRNPPPNSDPNL---RRFTIRGVPQQIEVARQLIDEKV 425
Score = 50.1 bits (118), Expect = 5e-06
Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 113 AAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
A +HQ T ++E+ VP + VG IIGRGGE I I SG KI ES G + R
Sbjct: 70 ALVHQ----RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSG--IPER 123
Query: 173 LIKISGTQKEVAAAKHLI 190
++GT + + AK L+
Sbjct: 124 PCVLTGTPESIEQAKRLL 141
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE----RVLLISGFPVQVC 109
EI VP + L+IG+ G NIK + +Q+GA +++ + R I G P Q+
Sbjct: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIE 415
Query: 110 KAKAAIHQ 117
A+ I +
Sbjct: 416 VARQLIDE 423
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 6e-13
Identities = 42/160 (26%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
E +VP V IIGR G I ++++++G +I + + G ER +++G P V AK
Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRL 163
Query: 115 IHQILTENTPVS------------EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDK 162
+ QI+ + P +++ +P G +IG+GGETI+ + + +G K+ +
Sbjct: 164 LDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQ 223
Query: 163 ESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
+ + ++I+G +V AK ++LE + + R+
Sbjct: 224 DGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFRE 263
Score = 63.2 bits (152), Expect = 6e-10
Identities = 54/189 (28%), Positives = 85/189 (44%), Gaps = 33/189 (17%)
Query: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGD 95
+RE R E + +G ++ I++ +P+ AV ++IGR G IK+++ G RI +D
Sbjct: 261 FREVRNEYGSRIGGNE-GIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP 319
Query: 96 ERVLLISGFPVQVCKAKAAIHQILTENTPVSE---------------------------- 127
ER+ I+G P C+ A I L +
Sbjct: 320 ERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQE 378
Query: 128 -QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLS-RLIKISGTQKEVAA 185
VP G IIG+GGETI+SI + SGA+I + + +L I GT +++
Sbjct: 379 FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDY 438
Query: 186 AKHLILEKV 194
A+ LI EK+
Sbjct: 439 ARQLIEEKI 447
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 20/155 (12%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFPVQVCKAK 112
E+ +P L+IG+ G IKQL+++ G + I ++ G ++ L I+G P +V +AK
Sbjct: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAK 248
Query: 113 AAIHQILTENTPVSE---------------QLSVPQRSVGRIIGRGGETIRSICKASGAK 157
+ +++ + E + +P+ +VG +IGR GE I+ I +G +
Sbjct: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308
Query: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILE 192
I K +GT R+ +I+G A +I +
Sbjct: 309 IQF-KPDDGT-TPERIAQITGPPDRCQHAAEIITD 341
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 125 VSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVA 184
++E+ VP VG IIGRGGE I I + SG KI +S G L R ++GT + V
Sbjct: 101 MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGG--LPERSCMLTGTPESVQ 158
Query: 185 AAKHLI 190
+AK L+
Sbjct: 159 SAKRLL 164
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 71.6 bits (174), Expect = 2e-12
Identities = 56/192 (29%), Positives = 91/192 (47%), Gaps = 35/192 (18%)
Query: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
Query: 94 GDERVLLISGFPVQVCKAKAAIHQILTENT-----------PVS---------------E 127
ERV LI G +A A+H + E PVS
Sbjct: 95 TTERVCLIQG----TVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
++ VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
Query: 188 HLILEKVSEDEE 199
LI++K+ ED +
Sbjct: 211 ELIIQKIQEDPQ 222
Score = 47.0 bits (110), Expect = 5e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
Query: 185 AAKHLILEKVSEDEELR 201
AA++LI ++++ ++ +R
Sbjct: 459 AAQYLITQRITYEQGVR 475
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101
T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +
Sbjct: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
Query: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136
SG P Q KA I Q + E+ L++ +V
Sbjct: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
Score = 32.7 bits (73), Expect = 0.91
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
Query: 105 PVQVCKAKAAIHQILT 120
P A+ I Q +T
Sbjct: 454 PAATQAAQYLITQRIT 469
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 71.2 bits (173), Expect = 2e-12
Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 34/180 (18%)
Query: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFP 105
E + +++ +P A IIG+ G I QL+K+TGA I + D ERV L+ G
Sbjct: 30 EGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQG-- 87
Query: 106 VQVCKAKAAIHQILTENTPVSEQ--------------------------LSVPQRSVGRI 139
+A A+H + E Q L VP + G I
Sbjct: 88 --TAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLI 145
Query: 140 IGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
IG+GG T++++ + SGA + ++ EG L R++ +SG ++V A I++KV ED +
Sbjct: 146 IGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205
Score = 49.7 bits (117), Expect = 7e-06
Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
+ ++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +SG P QV K
Sbjct: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHK 191
Query: 111 AKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGET 146
A +AI Q + E+ S L++ +V + T
Sbjct: 192 AVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPT 227
Score = 45.8 bits (107), Expect = 1e-04
Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)
Query: 117 QILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRL 173
++ E+ +++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R
Sbjct: 399 KLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT--RNRR 456
Query: 174 IKISGTQKEVAAAKHLILEKVSEDEELR 201
+ I+G+ AA++LI ++V+ ++ +R
Sbjct: 457 VTITGSPAATQAAQYLISQRVTYEQGVR 484
Score = 32.0 bits (71), Expect = 1.5
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGFPVQVCK 110
+E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G P
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 111 AKAAIHQILTENTPVSEQLSVPQR 134
A+ I Q +T V + S PQ+
Sbjct: 469 AQYLISQRVTYEQGV--RASNPQK 490
>gi|94421471 ring finger protein 17 [Homo sapiens]
Length = 1623
Score = 69.7 bits (169), Expect = 7e-12
Identities = 41/137 (29%), Positives = 75/137 (54%), Gaps = 6/137 (4%)
Query: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTV--HVGDIVAAPLP 365
+ V V P F++Q++ L + L+ + + Y++ E+L + V D
Sbjct: 680 VSVTVCHINSPGDFYLQLI--EGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKF 737
Query: 366 TNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
+G WYRA+V+G + +++ +VDFG+ +KD+R ++ +FL+ P +AI+C LA I
Sbjct: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIE 797
Query: 426 P--SGDQWEEEALDEFD 440
P QW +EA ++F+
Sbjct: 798 PYKRTMQWSKEAKEKFE 814
Score = 56.2 bits (134), Expect = 8e-08
Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 19/232 (8%)
Query: 271 WEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS 330
W+ PS + +E + + +P+ +F ++ L V++ P ++Q + + +
Sbjct: 882 WD-PSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN 940
Query: 331 LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVD 390
L L+ L +M YENS E + A + W R +++ + + +++ D
Sbjct: 941 L-LNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYD 999
Query: 391 FGD----NGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG--DQWEEEALDEFDRLTH 444
G N DC LR L + ++ ++ECSL I P+G D+W A D L
Sbjct: 1000 VGVELVVNVDC----LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS-LYL 1054
Query: 445 CADWKPLVAKISSYVQTGISTWP---KIYLYDTSNGKKLDIGLELVHKGYAI 493
++ ++ S + +TWP KI+ D G+++D+ L+ KG A+
Sbjct: 1055 TGAVATIILQVDS--EENNTTWPLPVKIFCRD-EKGERVDVSKYLIKKGLAL 1103
Score = 30.8 bits (68), Expect = 3.4
Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Query: 370 WYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGD 429
WYR +V+ + G + + ++D G P L + + +P I C L P G+
Sbjct: 1244 WYRGKVMEVV-GGAVRVQYLDHGFTEKIPQCHLYPILL-YPDIPQFCIPCQLHNTTPVGN 1301
Query: 430 QWEEEALDEFDRL 442
W+ +A++ +L
Sbjct: 1302 VWQPDAIEVLQQL 1314
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 66.2 bits (160), Expect = 7e-11
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 27/185 (14%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
E RVP V LIIGR G I ++++ +G ++ + + G ER + ++G P V KAK
Sbjct: 148 EYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMM 207
Query: 115 IHQILT-----------------ENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAK 157
+ I++ +N V E + +P G +IG+GGETI+ + + +G K
Sbjct: 208 LDDIVSRGRGGPPGQFHDNANGGQNGTVQE-IMIPAGKAGLVIGKGGETIKQLQERAGVK 266
Query: 158 ITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDE--------ELRKRIAHSAE 209
+ ++ + + ++I G +V A ++++ + E + E RI +
Sbjct: 267 MILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGID 326
Query: 210 TRVPR 214
VPR
Sbjct: 327 VPVPR 331
Score = 55.1 bits (131), Expect = 2e-07
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 33/172 (19%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTED-VGDERVLLISGFPVQVCKAKA 113
I++ VP+ +V ++IGR G IK+++ G RI +D G E++ I G P + A
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR 384
Query: 114 AIHQILTE----------------------------NTPVSEQ-LSVPQRSVGRIIGRGG 144
I+ +L P E S+P G +IGRGG
Sbjct: 385 IINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGG 444
Query: 145 ETIRSICKASGAKITCDKE--SEGTLLLSRLIKISGTQKEVAAAKHLILEKV 194
E +++I + +GA + ++ G +L I G+ +++ AK LI EK+
Sbjct: 445 ENVKAINQQTGAFVEISRQLPPNGDPNF-KLFIIRGSPQQIDHAKQLIEEKI 495
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/136 (28%), Positives = 65/136 (47%), Gaps = 18/136 (13%)
Query: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR---IDVDTEDVGDERVLLISGFP 105
G++ E+ +P L+IG+ G IKQL+++ G + I +++ ++ L I G P
Sbjct: 230 GQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDP 289
Query: 106 VQVCKAKAAIHQILTENTPVSE--------------QLSVPQRSVGRIIGRGGETIRSIC 151
+V +A + IL E + VP+ SVG +IGR GE I+ I
Sbjct: 290 YKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQ 349
Query: 152 KASGAKITCDKESEGT 167
+G +I K+ +GT
Sbjct: 350 NDAGVRIQF-KQDDGT 364
Score = 47.0 bits (110), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 123 TPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKE 182
T ++E+ VP VG IIGRGGE I I + SG K+ +S G L R + ++G +
Sbjct: 143 TSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGG--LPERSVSLTGAPES 200
Query: 183 VAAAKHLILEKVS 195
V AK ++ + VS
Sbjct: 201 VQKAKMMLDDIVS 213
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTE--DVGDE--RVLLISGFPVQVC 109
E+ +P L+IGR G N+K + +QTGA +++ + GD ++ +I G P Q+
Sbjct: 426 EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQID 485
Query: 110 KAKAAIHQ 117
AK I +
Sbjct: 486 HAKQLIEE 493
>gi|58197558 tudor domain containing 6 [Homo sapiens]
Length = 2096
Score = 64.7 bits (156), Expect = 2e-10
Identities = 48/184 (26%), Positives = 89/184 (48%), Gaps = 13/184 (7%)
Query: 264 VVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSP---DFSFHADEYLEVYVSASEHPNH 320
V+ + + E+ + S +S A+ + E EI P + + + V ++P+
Sbjct: 446 VLQSQATEEEEPETSQSQSPAEEVDE----EISLPALRSIRLKMNAFYDAQVEFVKNPSE 501
Query: 321 FWIQIVGSRSLQLDKLVNEMTQHYENSVPED---LTVHVGDIVAAPLPTNGSWYRARVLG 377
FWI++ ++ KL+ M Y ++ D L D+ NG +YRA ++
Sbjct: 502 FWIRL-RKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKENG-YYRA-IVT 558
Query: 378 TLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALD 437
L++ ++D++ VD G++ + D+R L F LP A++C+LA I P G W +EA+
Sbjct: 559 KLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPLGKTWSQEAVS 618
Query: 438 EFDR 441
F +
Sbjct: 619 FFKK 622
Score = 58.9 bits (141), Expect = 1e-08
Identities = 46/164 (28%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 308 LEVYVSASEHPNHFWIQIVGSRSLQ-LDKLVNEMTQHYENSVPEDLTVHVGDIVA--APL 364
+EV VS E+P +FW Q+ +R++Q L L++++ + +N+ H + +A A
Sbjct: 774 VEVRVSYVENPGYFWCQL--TRNIQGLKTLMSDIQYYCKNTAAP----HQRNTLACLAKR 827
Query: 365 PTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLAR- 423
N W RA + G ++++ FVD+GD +K++ ++ +FL + QA CSL
Sbjct: 828 TVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNL 887
Query: 424 IAPSGDQ---WEEEALDEFDRLTHCADWKPLVAKISSYVQTGIS 464
I P G W+ +A+ F+ A K L K + + I+
Sbjct: 888 IQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCTIFALASIN 931
Score = 53.9 bits (128), Expect = 4e-07
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 308 LEVYVSASEHPNHFWIQIVGSRSLQLDKL----VNEMTQHYENSVPEDLTVHVGDIVAAP 363
+ Y + + P +FW Q + LQ ++ E N +P ++GD
Sbjct: 1521 IRAYATVIDGPEYFWCQFADTEKLQCLEVEVQTAGEQVADRRNCIP---CPYIGDPCIVR 1577
Query: 364 LPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDC-PLKDLRALRSDFLSLPFQAIECSLA 422
+G +YRA + E+ + + VDFG+ DC K L A+ S+ LS+P QA C L+
Sbjct: 1578 YREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFPCCLS 1637
Query: 423 RIAPSGDQWEEEALDEF 439
S +E D F
Sbjct: 1638 GFNISEGLCSQEGNDYF 1654
Score = 41.2 bits (95), Expect = 0.003
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 11/120 (9%)
Query: 310 VYVSASEHPNHFWIQIVGSRSL--QLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
VY++ + P F+ Q+ + ++ QL + ++++ N L + G + A T+
Sbjct: 990 VYITHIDDPWTFYCQLARNANILEQLSCSITQLSKVLLNLKTSPL--NPGTLCLAKY-TD 1046
Query: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD---FLSLPFQAIECSLARI 424
G+WYR V+ E ++FVDFG+ DL + SD L LP QA+ CSL+ I
Sbjct: 1047 GNWYRGIVI---EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRCSLSDI 1103
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 310 VYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTN 367
VYVS + F++Q++ + L + +N + E V L GD++ A P +
Sbjct: 1309 VYVSHINDLSDFYVQLIEDEAEISHLSERLNSVKTRPEYYVGPPL--QRGDMICAVFPED 1366
Query: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
WYRA + N L + F+D+G+ + L LP I CSL
Sbjct: 1367 NLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSL 1420
Score = 31.6 bits (70), Expect = 2.0
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Query: 367 NGSWYRARVLGTLENGNL-DLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIA 425
+G WYRA +L T + VD+G LR L ++ +P C+L +
Sbjct: 323 DGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLW 382
Query: 426 PSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLE 485
G W + + L K + AKI Y + +Y D N ++ G++
Sbjct: 383 DGGRGWSRSQVGDLKTLIL---GKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRV-FGVQ 438
Query: 486 LVHKGYAIELPEDIEENRAVPDMLKDMATETDASLS 521
+ + EE + A E D +S
Sbjct: 439 SCCLADRVLQSQATEEEEPETSQSQSPAEEVDEEIS 474
Score = 29.6 bits (65), Expect = 7.7
Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 10/82 (12%)
Query: 370 WYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSG- 428
W+R RV+ + ++ +D G L R +F +LP + + C LA + P+G
Sbjct: 81 WHRCRVVSRQAQESR-VFLLDEGRTITAGAGSLAPGRREFFNLPSEVLGCVLAGLVPAGC 139
Query: 429 --------DQWEEEALDEFDRL 442
W +A+D L
Sbjct: 140 GAGSGEPPQHWPADAVDFLSNL 161
>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
Length = 903
Score = 63.9 bits (154), Expect = 4e-10
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 14/147 (9%)
Query: 349 PEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGN-LDLYFVDFGDNGDCPLKDLRALRS 407
P ++TV I AAP +G+W+RA+V+ + E N +++ +VD+G + LR +RS
Sbjct: 758 PVEITV----ICAAP-GADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRS 812
Query: 408 DFLSLPFQAIECSLARIAP--SGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGIST 465
DF++LPFQ E L + P DQ+ EA +T L+A+++SY TG+
Sbjct: 813 DFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNT---ALLAQVTSYSPTGL-- 867
Query: 466 WPKIYLYDTSNGKKLDIGLELVHKGYA 492
P I L+ + + I LV +G A
Sbjct: 868 -PLIQLWSVVGDEVVLINRSLVERGLA 893
Score = 34.3 bits (77), Expect = 0.31
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIK---ISGTQKEVA 184
++ VP+ VGR+IG+ G + + + SGAKI TL ++ ++ I G+Q V
Sbjct: 611 EIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYI-----STLPYTQSVQICHIEGSQHHVD 665
Query: 185 AAKHLILEKVSE 196
A +LI +K E
Sbjct: 666 KALNLIGKKFKE 677
Score = 31.2 bits (69), Expect = 2.6
Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 9/63 (14%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAI 115
E+ VP+ V +IG+QG + L++ +GA+I + T L VQ+C + +
Sbjct: 611 EIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYIST---------LPYTQSVQICHIEGSQ 661
Query: 116 HQI 118
H +
Sbjct: 662 HHV 664
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/212 (26%), Positives = 93/212 (43%), Gaps = 51/212 (24%)
Query: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
Query: 94 GDERVLLISG------------------FPVQVCKAKAA-------------IHQIL--- 119
ERV LI G P V K + I Q L
Sbjct: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSS 154
Query: 120 ---TENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGT 167
T+++P ++ VP + G IIG+GG T++++ + SGA + ++ +G
Sbjct: 155 PTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI 214
Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
L R++ +SG ++ A LI++K+ ED +
Sbjct: 215 NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQ 246
Score = 47.4 bits (111), Expect = 4e-05
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 47/235 (20%)
Query: 73 ANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT-ENTPVSEQLSV 131
A I+Q TG ID+D D P++ + + T E+ ++ +
Sbjct: 5 APIQQNGTHTGVPIDLDPPDSRKR--------PLEAPPEAGSTKRTNTGEDGQYFLKVLI 56
Query: 132 PQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVAAAKH 188
P + G IIG+GG+TI + K +GA I K + GT R+ I GT + + A
Sbjct: 57 PSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT--TERVCLIQGTVEALNAVHG 114
Query: 189 LILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMT-EPGGAGEPALWKNTSSSMEPT 247
I EK+ E + V + +P+S+ + T P + T++ P+
Sbjct: 115 FIAEKIREMPQ-----------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPS 163
Query: 248 APLVTPPP-----------------KGGGDMAVVVSKEGSW----EKPSDDSFQK 281
P+ T KGG + V+ + G+W +KP + Q+
Sbjct: 164 DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQE 218
Score = 47.0 bits (110), Expect = 5e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 482
Query: 185 AAKHLILEKVSEDEELR 201
AA++LI ++++ ++ +R
Sbjct: 483 AAQYLITQRITYEQGVR 499
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +SG P Q K
Sbjct: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
Query: 111 AKAAIHQILTENTPVSEQLSVPQRSV 136
A I Q + E+ L++ +V
Sbjct: 233 AVELIIQKIQEDPQSGSCLNISYANV 258
Score = 32.7 bits (73), Expect = 0.91
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 419 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 477
Query: 105 PVQVCKAKAAIHQILT 120
P A+ I Q +T
Sbjct: 478 PAATQAAQYLITQRIT 493
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 61.2 bits (147), Expect = 2e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 506
Query: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
E ++ R+I + I+++V + E+
Sbjct: 507 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 47/223 (21%)
Query: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
Query: 89 -DTEDVGDERVLLISGFPVQVCKA----------KAAIHQILTENT-------------- 123
D ER + + G V+ C + +A + +L NT
Sbjct: 314 QDLSIYNPERTITVKG-TVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQF 372
Query: 124 ---------PVSE--QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
P E L +P ++VG IIG+ G I+ + + +GA I +EG + R
Sbjct: 373 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSER 431
Query: 173 LIKISGTQKEVAAAKHLILEKVSEDE--ELRKRIAHSAETRVP 213
++ I+G + A+ I K+ E+ ++ + A RVP
Sbjct: 432 MVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVP 474
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
Query: 107 QVCKAKAAIHQILTE 121
A+ I +I+ +
Sbjct: 524 ASQTAQRKIREIVQQ 538
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 61.2 bits (147), Expect = 2e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
Query: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
E ++ R+I + I+++V + E+
Sbjct: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
Query: 89 -DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
D ER + + G A+ I + L E
Sbjct: 314 QDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 507 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 566
Query: 107 QVCKAKAAIHQILTE 121
A+ I +I+ +
Sbjct: 567 ASQTAQRKIREIVQQ 581
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 10/161 (6%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE--RVLLISGFPVQVCKAK 112
+ + +P +V IIG+QG +IKQL + GA I + + D R+++I+G P KA+
Sbjct: 408 VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQ 467
Query: 113 AAIHQILTENTPVSEQ--------LSVPQRSVGRIIGRGGETIRSICKASGAKITCDKES 164
I+ + E VS + + VP + GR+IG+GG+T+ + S A++ ++
Sbjct: 468 GRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQ 527
Query: 165 EGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIA 205
++KI+G A+ I E +++ ++ +++ A
Sbjct: 528 TPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKA 568
Score = 60.8 bits (146), Expect = 3e-09
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 14/160 (8%)
Query: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFPVQVC 109
D+ + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + I P
Sbjct: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
Query: 110 KAKAAIHQIL---------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
A +I +I+ TE P+ ++ VGR+IG+ G ++ I + + KIT
Sbjct: 255 AACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITI 312
Query: 161 DKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
E TL R I + G + A A+ I++K+ E E
Sbjct: 313 SPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYE 352
Score = 37.4 bits (85), Expect = 0.037
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 35 RRYRESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DT 90
R Y + +EE E+ +E +RVP A +IG+ G + +L+ + A + V T
Sbjct: 469 RIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQT 528
Query: 91 EDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
D D+ V+ I+G A+ I +ILT+
Sbjct: 529 PDENDQVVVKITGHFYACQVAQRKIQEILTQ 559
Score = 36.6 bits (83), Expect = 0.063
Identities = 50/247 (20%), Positives = 96/247 (38%), Gaps = 64/247 (25%)
Query: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
SA IL ++E+++ + T ++I +++ V +IG++G N+K++ + T +
Sbjct: 254 SAACKSILEIMHKEAQDIKFT----EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTK 309
Query: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTEN------------------- 122
I + + ER + + G KA+ I + + E+
Sbjct: 310 ITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLN 369
Query: 123 ------------------------TPVSEQ----------LSVPQRSVGRIIGRGGETIR 148
TP Q L +P SVG IIG+ G+ I+
Sbjct: 370 LNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIK 429
Query: 149 SICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL--RKRIAH 206
+ + +GA I +E R++ I+G + A+ I K+ E+ + ++ +
Sbjct: 430 QLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKL 488
Query: 207 SAETRVP 213
A RVP
Sbjct: 489 EAHIRVP 495
>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.7 bits (143), Expect = 7e-09
Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)
Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
+P++FW++ R+ + +++ + + Y+ +++ + G A + +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697
Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
V+ + +++YF+D+G+ P D++ L +F LP A+ CSLA I P D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756
Query: 434 EALDEFDRL 442
A+D F +L
Sbjct: 757 AAIDYFKKL 765
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
V VS++ P+ F+ Q++ + +L+ L MT HY+ E T ++ NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
W+R + L + ++F+D+G + P ++ L+ DF+ +P + CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)
Query: 294 EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
++P P +A ++ YVS +P +F IQ+ + S ++L +N + +
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486
Query: 352 LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
+ VGD+V A + + YRA + L + ++ F+D+G++ + L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546
Query: 412 LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
+P I L+ + + W+++ +D F H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 296 PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
P ++ F LEV S P F Q+ +S L L+ ++ +Y S+ D
Sbjct: 892 PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947
Query: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
+G A +G W RA VL T + +D+ FVD+G ++DL A+ FL L Q
Sbjct: 948 IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005
Query: 416 AIECSL 421
A C L
Sbjct: 1006 AFRCCL 1011
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Query: 309 EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
EVY+S P F+ Q+ G + L+ + ++T+ + + + +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
YRA + T + +YFVDFG+ G+ L+ + A + L P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229
Score = 36.2 bits (82), Expect = 0.082
Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)
Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
FQ E + P+ ++ S F +L+V ++ S P ++ G +S + +
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187
Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
+ + + +++ V + + +G W R RV+ +N + +D G+
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246
Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
+ + + LP + + A I P G++W +AL+ F L + ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298
Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
YVQ + ++ + L++ L + G + L ++ E + +PD+L+
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358
Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
E L K +S +I H L L S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382
>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.7 bits (143), Expect = 7e-09
Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)
Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
+P++FW++ R+ + +++ + + Y+ +++ + G A + +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697
Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
V+ + +++YF+D+G+ P D++ L +F LP A+ CSLA I P D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756
Query: 434 EALDEFDRL 442
A+D F +L
Sbjct: 757 AAIDYFKKL 765
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
V VS++ P+ F+ Q++ + +L+ L MT HY+ E T ++ NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
W+R + L + ++F+D+G + P ++ L+ DF+ +P + CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)
Query: 294 EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
++P P +A ++ YVS +P +F IQ+ + S ++L +N + +
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486
Query: 352 LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
+ VGD+V A + + YRA + L + ++ F+D+G++ + L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546
Query: 412 LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
+P I L+ + + W+++ +D F H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 296 PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
P ++ F LEV S P F Q+ +S L L+ ++ +Y S+ D
Sbjct: 892 PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947
Query: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
+G A +G W RA VL T + +D+ FVD+G ++DL A+ FL L Q
Sbjct: 948 IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005
Query: 416 AIECSL 421
A C L
Sbjct: 1006 AFRCCL 1011
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Query: 309 EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
EVY+S P F+ Q+ G + L+ + ++T+ + + + +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
YRA + T + +YFVDFG+ G+ L+ + A + L P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229
Score = 36.2 bits (82), Expect = 0.082
Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)
Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
FQ E + P+ ++ S F +L+V ++ S P ++ G +S + +
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187
Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
+ + + +++ V + + +G W R RV+ +N + +D G+
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246
Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
+ + + LP + + A I P G++W +AL+ F L + ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298
Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
YVQ + ++ + L++ L + G + L ++ E + +PD+L+
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358
Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
E L K +S +I H L L S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382
>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.7 bits (143), Expect = 7e-09
Identities = 34/129 (26%), Positives = 68/129 (52%), Gaps = 5/129 (3%)
Query: 317 HPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHV---GDIVAAPLPTNGSWYRA 373
+P++FW++ R+ + +++ + + Y+ +++ + G A + +YRA
Sbjct: 639 NPSNFWVRTNDHRN-EFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDRRFYRA 697
Query: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
V+ + +++YF+D+G+ P D++ L +F LP A+ CSLA I P D W +
Sbjct: 698 -VITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWTK 756
Query: 434 EALDEFDRL 442
A+D F +L
Sbjct: 757 AAIDYFKKL 765
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 310 VYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL-TVHVGDIVAAPLPTNG 368
V VS++ P+ F+ Q++ + +L+ L MT HY+ E T ++ NG
Sbjct: 391 VKVSSALSPSKFYCQLI-KWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVARRRNG 449
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
W+R + L + ++F+D+G + P ++ L+ DF+ +P + CSL
Sbjct: 450 QWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSL 502
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 8/155 (5%)
Query: 294 EIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRS--LQLDKLVNEMTQHYENSVPED 351
++P P +A ++ YVS +P +F IQ+ + S ++L +N + +
Sbjct: 1431 DLPQPQIYLNAK--VKGYVSNISNPANFHIQLAENESVIIRLADALNATARRLRER--KS 1486
Query: 352 LTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLS 411
+ VGD+V A + + YRA + L + ++ F+D+G++ + L+ +FL+
Sbjct: 1487 VKPLVGDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLT 1546
Query: 412 LPFQAIECSLARIA--PSGDQWEEEALDEFDRLTH 444
+P I L+ + + W+++ +D F H
Sbjct: 1547 VPQLGIHAFLSGVKWNEPDEIWDDKTVDYFTSKVH 1581
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 296 PSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVH 355
P ++ F LEV S P F Q+ +S L L+ ++ +Y S+ D
Sbjct: 892 PYKEYIFRPGTVLEVKCSCYYGPGDFSCQLQ-CKSEDLKLLMEQIQNYY--SIHSD-PYE 947
Query: 356 VGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQ 415
+G A +G W RA VL T + +D+ FVD+G ++DL A+ FL L Q
Sbjct: 948 IGQ-TACVAKYSGKWCRAAVL-TQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQ 1005
Query: 416 AIECSL 421
A C L
Sbjct: 1006 AFRCCL 1011
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Query: 309 EVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNG 368
EVY+S P F+ Q+ G + L+ + ++T+ + + + +G
Sbjct: 1114 EVYISHIYSPQKFYCQL-GRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCISKYVEDG 1172
Query: 369 SWYRARVLGTLENGNLDLYFVDFGDN---GDCPLKDLRALRSDFLSLPFQAIECSLA 422
YRA + T + +YFVDFG+ G+ L+ + A + L P QAI+C L+
Sbjct: 1173 LSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKCFLS 1229
Score = 36.2 bits (82), Expect = 0.082
Identities = 52/271 (19%), Positives = 107/271 (39%), Gaps = 24/271 (8%)
Query: 279 FQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEH---PNHFWIQIVGSRSLQLDK 335
FQ E + P+ ++ S F +L+V ++ S P ++ G +S + +
Sbjct: 131 FQLWEERPDPQQRFLKMDSTSF---LPTFLDVDLTISHIKCLPKDILVKFQGIKSNECEF 187
Query: 336 LVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNG 395
+ + + +++ V + + +G W R RV+ +N + +D G+
Sbjct: 188 DYHVLQREIQHTPKVKNNVEIDEFCLVEERVSGEWQRGRVMEK-KNELYTVLLIDRGEEL 246
Query: 396 DCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKI 455
+ + + LP + + A I P G++W +AL+ F L + ++
Sbjct: 247 RVAGPQIASACGNLFELPPRVVFGIFANILPVGEKWSPKALNYFKSL--------VGIQV 298
Query: 456 SSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEEN--RAVPDMLKDMA 513
YVQ + ++ + L++ L + G + L ++ E + +PD+L+
Sbjct: 299 KGYVQAILPLQMFLFEVPKIISQALELQLGRLVDGDSFRLIVEMLEEFPQQMPDLLQHKR 358
Query: 514 TETDASLSTLLTETKKSSGEITHTLSCLSLS 544
E L K +S +I H L L S
Sbjct: 359 PE-------LSLGNKDTSLDIQHVLDKLQPS 382
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 297
Query: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 298 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 357
Query: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 358 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 402
Score = 31.6 bits (70), Expect = 2.0
Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 51 DDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFPV 106
D++ +++ V +IG++G N+K++ + T +I + D ER + + G
Sbjct: 136 DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE 195
Query: 107 QVCKAKAAIHQILTE 121
C+A+ I + + E
Sbjct: 196 NCCRAEQEIMKKVRE 210
Score = 31.6 bits (70), Expect = 2.0
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 136 VGRIIGRGGETIRSICKASGAKITCDKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKV 194
VGR+IG+ G ++ + + + KIT + TL R I + G + A+ I++KV
Sbjct: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208
Query: 195 SEDEE 199
E E
Sbjct: 209 REAYE 213
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 386 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 436
Query: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 437 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 496
Query: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 497 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 541
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 10/158 (6%)
Query: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFP---V 106
DI + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + + P
Sbjct: 195 DIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCS 254
Query: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
CK I ++T ++++ + VGR+IG+ G ++ + + + KIT
Sbjct: 255 SACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS 314
Query: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
+ TL R I + G + A+ I++KV E E
Sbjct: 315 LQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352
Score = 32.7 bits (73), Expect = 0.91
Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
S+ IL ++E+++ + D++ +++ V +IG++G N+K++ + T +
Sbjct: 254 SSACKMILEIMHKEAKDTKTA----DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
Query: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
I + D ER + + G C+A+ I + + E
Sbjct: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+ I + + + V IIG++G +K++R+++GARI++ +E ER++ I+G + KA
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
Query: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
A I + T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
Query: 160 CDKESEGTLL---LSRLIKISGT 179
+ G +L R + ISGT
Sbjct: 164 ---QVAGDMLPNSTERAVTISGT 183
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 68/211 (32%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISGFP----- 105
+ + + VP +IG+ G+ IK++R+ TGA++ V D ER + ISG P
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
Query: 106 --VQVCKAK-----------------AAIHQILTENTPV--------------------- 125
Q+C +HQ+ + TP
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
Query: 126 -------------------SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEG 166
+ +L++P +G IIGR G I I + SGA+I +EG
Sbjct: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
Query: 167 TLLLSRLIKISGTQKEVAAAKHLILEKVSED 197
+ R I I+GT ++ A++LI +++ +
Sbjct: 310 S--SERQITITGTPANISLAQYLINARLTSE 338
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)
Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
N ++ +L + + VG IIG+ GET++ + + SGA+I SEG R++ I+G
Sbjct: 43 NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
Query: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
+ A +I K ED + +++S T P P+++R
Sbjct: 99 AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+ I + + + V IIG++G +K++R+++GARI++ +E ER++ I+G + KA
Sbjct: 46 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
Query: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
A I + T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
Query: 160 CDKESEGTLL---LSRLIKISGT 179
+ G +L R + ISGT
Sbjct: 164 ---QVAGDMLPNSTERAVTISGT 183
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114
E+ +P + + IIGRQG I ++R+ +GA+I + G ER + I+G P + A+
Sbjct: 297 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYL 356
Query: 115 IHQILT 120
I+ LT
Sbjct: 357 INARLT 362
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 2/72 (2%)
Query: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
+ +L++P +G IIGR G I I + SGA+I +EG+ R I I+GT ++
Sbjct: 295 THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISL 352
Query: 186 AKHLILEKVSED 197
A++LI +++ +
Sbjct: 353 AQYLINARLTSE 364
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)
Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
N ++ +L + + VG IIG+ GET++ + + SGA+I SEG R++ I+G
Sbjct: 43 NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
Query: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221
+ A +I K ED + +++S T P P+++R
Sbjct: 99 AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 57.0 bits (136), Expect = 4e-08
Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)
Query: 305 DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363
D L + V+ HFW +I + S L KL E+ Q VP H + AP
Sbjct: 897 DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954
Query: 364 LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421
++RA+VL N + +++FVD+G+ L L + FL LPFQA+E +
Sbjct: 955 FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013
Query: 422 ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 475
++ PS G W + A F L L+ K+ S V + + +Y Y +
Sbjct: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067
Query: 476 NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 529
++I L+ +GYA EL E+ E++ ++LK + ++ TD S+ + + +K
Sbjct: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 56.6 bits (135), Expect = 6e-08
Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 21/147 (14%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI-SEGNCPERIITLTGPTNAIFKAF 72
Query: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159
+ + K + I+ +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV- 131
Query: 160 CDKESEGTLL---LSRLIKISGTQKEV 183
+ G +L R I I+G + V
Sbjct: 132 ---QVAGDMLPNSTERAITIAGVPQSV 155
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Query: 119 LTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
L +T + +L++P +G IIGR G I I + SGA+I EG+ R + I+G
Sbjct: 274 LDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITG 331
Query: 179 TQKEVAAAKHLILEKVSEDE 198
+ ++ A++LI ++S ++
Sbjct: 332 SAASISLAQYLINARLSSEK 351
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
N ++ +L + + VG IIG+ GE+++ I + SGA+I SEG R+I ++G
Sbjct: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGN-CPERIITLTGPTN 66
Query: 182 EVAAAKHLILEKVSED 197
+ A +I++K+ ED
Sbjct: 67 AIFKAFAMIIDKLEED 82
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE-RVLLISGFPVQVCKAKAA 114
E+ +P + IIGRQGANI ++R+ +GA+I + G R + I+G + A+
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYL 342
Query: 115 IHQILT 120
I+ L+
Sbjct: 343 INARLS 348
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 8/108 (7%)
Query: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 91 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV------PQRSVGRIIGRGGE 145
P V + I ++ E S Q V P + +I GG+
Sbjct: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ 198
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
E+ I + + ++ K IIG+ GANIK++R+++ +ID+ E+ E ++I+G
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637
Query: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
A++ I I + ++E ++S+P + +IG G IRSI + G I E G
Sbjct: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696
Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
S + I G +V AK +L E +
Sbjct: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+ IE+ VP + + +IG++G+ I+++ + I V ++ + ++ I+G + +AK
Sbjct: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031
Query: 113 AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
A + + + E E ++V + +IIGR G I I I +
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091
Query: 164 SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
+G + I I+G +K AA+ IL V E E++
Sbjct: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 39 ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
E +++L + E+ +++R E K +IG+ G I+++R TGAR+ +
Sbjct: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769
Query: 95 DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
D+ ++ I G V +A+ + ++ + V + + V + + R G+ +R I +
Sbjct: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
Query: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
G + S GT S + + G + V AAK I E + E+L ++ + E +P
Sbjct: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881
Query: 214 RK 215
+K
Sbjct: 882 QK 883
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)
Query: 67 IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
IIGR+GA I Q+R + I +D G++ + I+G+ A+ AI +I+ E
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Query: 124 PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
VSE + + R RIIG G+ IR I I + + ++G + V
Sbjct: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183
Query: 184 AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
A IL + +EE + S +V K P E+ P G A W +S
Sbjct: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237
Query: 242 SSMEPTAPLVTPPPKGGGDMA 262
S P P G +A
Sbjct: 1238 SEKAPDMSSSEEFPSFGAQVA 1258
Score = 39.7 bits (91), Expect = 0.007
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 69 GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
G Q ++ ++TGA +++ +D G +++SG V KA+ I + T S
Sbjct: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
+++P+ +IG+ GE ++ + + KI + + S IKI+GT++ + A+
Sbjct: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209
Query: 188 HLILEKVSEDEE 199
H +L +E ++
Sbjct: 210 HEVLLISAEQDK 221
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+E+ + + + +IG+ GANI +++ Q RI D+E ++ I G P V +AK
Sbjct: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494
Query: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
+ ++ + ++ L + QR IIG+ GE IR I
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
Score = 32.3 bits (72), Expect = 1.2
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
Y E +++ T I +E++ Q K +IG +G +++++ ++TG +++ D E
Sbjct: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339
Query: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
V+L G P ++ +A ++ N+ ++ P IIG+ G+ + I
Sbjct: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390
Score = 32.0 bits (71), Expect = 1.5
Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)
Query: 59 VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
+P+E + +IG+ G ++ L +T +I + D ++ I+G + KA+ + I
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215
Query: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
E + E+L V + I G + I + +G +I S ++R +
Sbjct: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270
Query: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
+KE A ++K+ E+++ + + K I + + E ++
Sbjct: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330
Query: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
S S+ T L P K G + V +K S+
Sbjct: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVC 109
E+ I + + ++ K IIG+ GANIK++R+++ +ID+ E+ E ++I+G
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE-TIIITGKRANCE 637
Query: 110 KAKAAIHQILTENTPVSE-QLSVPQRSVGRIIGRGGETIRSIC-KASGAKITCDKESEGT 167
A++ I I + ++E ++S+P + +IG G IRSI + G I E G
Sbjct: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG- 696
Query: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDE 198
S + I G +V AK +L E +
Sbjct: 697 ---SDTVVIRGPSSDVEKAKKQLLHLAEEKQ 724
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+ IE+ VP + + +IG++G+ I+++ + I V ++ + ++ I+G + +AK
Sbjct: 973 VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD-IIAITGLAANLDRAK 1031
Query: 113 AAIHQILTENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE 163
A + + + E E ++V + +IIGR G I I I +
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDK 1091
Query: 164 SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEEL 200
+G + I I+G +K AA+ IL V E E++
Sbjct: 1092 DDGNQPQDQ-ITITGYEKNTEAARDAILRIVGELEQM 1127
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 39 ESREERLTFVGED----DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG 94
E +++L + E+ +++R E K +IG+ G I+++R TGAR+ +
Sbjct: 710 EKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDK 769
Query: 95 DERVLLISGFPVQVCKAKAAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKA 153
D+ ++ I G V +A+ + ++ + V + + V + + R G+ +R I +
Sbjct: 770 DQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEE 829
Query: 154 SGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVP 213
G + S GT S + + G + V AAK I E + E+L ++ + E +P
Sbjct: 830 YGGVMVSFPRS-GT--QSDKVTLKGAKDCVEAAKKRIQEII---EDLEAQV--TLECAIP 881
Query: 214 RK 215
+K
Sbjct: 882 QK 883
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 14/201 (6%)
Query: 67 IIGRQGANIKQLRKQTGARIDVDTEDVGDERV--LLISGFPVQVCKAKAAIHQILTE-NT 123
IIGR+GA I Q+R + I +D G++ + I+G+ A+ AI +I+ E
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Query: 124 PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEV 183
VSE + + R RIIG G+ IR I I + + ++G + V
Sbjct: 1127 MVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPD---PNCVTVTGLPENV 1183
Query: 184 AAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEP--GGAGEPALWKNTS 241
A IL + +EE + S +V K P E+ P G A W +S
Sbjct: 1184 EEAIDHIL---NLEEEYLADVVDSEALQVYMKPP---AHEEAKAPSRGFVVRDAPWTASS 1237
Query: 242 SSMEPTAPLVTPPPKGGGDMA 262
S P P G +A
Sbjct: 1238 SEKAPDMSSSEEFPSFGAQVA 1258
Score = 39.7 bits (91), Expect = 0.007
Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 9/132 (6%)
Query: 69 GRQGANIKQLRKQTGARIDVD-TEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSE 127
G Q ++ ++TGA +++ +D G +++SG V KA+ I + T S
Sbjct: 98 GEQAKICLEIMQRTGAHLELSLAKDQGLS--IMVSGKLDAVMKARKDI--VARLQTQASA 153
Query: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAK 187
+++P+ +IG+ GE ++ + + KI + + S IKI+GT++ + A+
Sbjct: 154 TVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDP----SNQIKITGTKEGIEKAR 209
Query: 188 HLILEKVSEDEE 199
H +L +E ++
Sbjct: 210 HEVLLISAEQDK 221
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQ--TGARIDVDTEDVGDERVLLISGFPVQVCKAK 112
+E+ + + + +IG+ GANI +++ Q RI D+E ++ I G P V +AK
Sbjct: 438 VEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE---KSNLIRIEGDPQGVQQAK 494
Query: 113 AAIHQILTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
+ ++ + ++ L + QR IIG+ GE IR I
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREI 533
Score = 32.3 bits (72), Expect = 1.2
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 37 YRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
Y E +++ T I +E++ Q K +IG +G +++++ ++TG +++ D E
Sbjct: 288 YEEKKKKTTT------IAVEVKKSQH--KYVIGPKGNSLQEILERTGVSVEIPPSDSISE 339
Query: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSI 150
V+L G P ++ +A ++ N+ ++ P IIG+ G+ + I
Sbjct: 340 TVIL-RGEPEKLGQALTEVY--AKANSFTVSSVAAPSWLHRFIIGKKGQNLAKI 390
Score = 32.0 bits (71), Expect = 1.5
Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 7/214 (3%)
Query: 59 VPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQI 118
+P+E + +IG+ G ++ L +T +I + D ++ I+G + KA+ + I
Sbjct: 157 IPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQI-KITGTKEGIEKARHEVLLI 215
Query: 119 LTE-NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKIS 177
E + E+L V + I G + I + +G +I S ++R +
Sbjct: 216 SAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPS-----VNRTEIVF 270
Query: 178 GTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALW 237
+KE A ++K+ E+++ + + K I + + E ++
Sbjct: 271 TGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVE 330
Query: 238 KNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSW 271
S S+ T L P K G + V +K S+
Sbjct: 331 IPPSDSISETVILRGEPEKLGQALTEVYAKANSF 364
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,866,317
Number of Sequences: 37866
Number of extensions: 1052996
Number of successful extensions: 3121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2794
Number of HSP's gapped (non-prelim): 271
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.