Guide to the Human Genome
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Search of human proteins with 145275187

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145275187 tRNA methyltransferase 5 [Homo sapiens]
         (509 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145275187 tRNA methyltransferase 5 [Homo sapiens]                 1021   0.0  
gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo sa...    43   6e-04
gi|216548193 RAD54-like protein [Homo sapiens]                         34   0.28 
gi|216548186 RAD54-like protein [Homo sapiens]                         34   0.28 
gi|163792194 N2,N2-dimethylguanosine tRNA methyltransferase-like...    32   1.4  
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    31   2.3  
gi|118600967 shroom family member 4 [Homo sapiens]                     30   4.0  
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    30   6.8  
gi|169160671 PREDICTED: similar to hCG2039305 [Homo sapiens]           29   8.9  
gi|169161659 PREDICTED: similar to hCG2039305 [Homo sapiens]           29   8.9  
gi|113408590 PREDICTED: similar to hCG2039305 [Homo sapiens]           29   8.9  
gi|47132591 protein kinase N1 isoform 1 [Homo sapiens]                 29   8.9  
gi|47132589 protein kinase N1 isoform 2 [Homo sapiens]                 29   8.9  
gi|7662230 ring finger protein 40 [Homo sapiens]                       29   8.9  

>gi|145275187 tRNA methyltransferase 5 [Homo sapiens]
          Length = 509

 Score = 1021 bits (2640), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MVLWILWRPFGFSGRFLKLESHSITESKSLIPVAWTSLTQMLLEAPGIFLLGQRKRFSTM 60
           MVLWILWRPFGFSGRFLKLESHSITESKSLIPVAWTSLTQMLLEAPGIFLLGQRKRFSTM
Sbjct: 1   MVLWILWRPFGFSGRFLKLESHSITESKSLIPVAWTSLTQMLLEAPGIFLLGQRKRFSTM 60

Query: 61  PETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQR 120
           PETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQR
Sbjct: 61  PETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQR 120

Query: 121 PGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQLNVSPQISKYNLELTYEHF 180
           PGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQLNVSPQISKYNLELTYEHF
Sbjct: 121 PGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQLNVSPQISKYNLELTYEHF 180

Query: 181 KSEEILRAVLPEGQDVTSGFSRIGHIAHLNLRDHQLSFKHLIGQVMIDKNPGITSAVNKI 240
           KSEEILRAVLPEGQDVTSGFSRIGHIAHLNLRDHQLSFKHLIGQVMIDKNPGITSAVNKI
Sbjct: 181 KSEEILRAVLPEGQDVTSGFSRIGHIAHLNLRDHQLSFKHLIGQVMIDKNPGITSAVNKI 240

Query: 241 NNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGD 300
           NNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGD
Sbjct: 241 NNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGD 300

Query: 301 VLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFL 360
           VLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFL
Sbjct: 301 VLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFL 360

Query: 361 QGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIEFLSAFKWLLDGQPCSSEFLPIVHCYS 420
           QGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIEFLSAFKWLLDGQPCSSEFLPIVHCYS
Sbjct: 361 QGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIEFLSAFKWLLDGQPCSSEFLPIVHCYS 420

Query: 421 FSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQTRN 480
           FSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQTRN
Sbjct: 421 FSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQTRN 480

Query: 481 PENHEDPPLKRQRTAEAFSDEKTQIVSNT 509
           PENHEDPPLKRQRTAEAFSDEKTQIVSNT
Sbjct: 481 PENHEDPPLKRQRTAEAFSDEKTQIVSNT 509


>gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo
           sapiens]
          Length = 448

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 4/143 (2%)

Query: 254 VLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFA 313
           +L G+   +  V +N   Y+FD ++  ++    TE  R+  L   G+VL D++AG+G F 
Sbjct: 191 LLLGDHGWVEHV-DNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFT 249

Query: 314 IP--VAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKV-FNLDGKDFLQGPVKEELMQ 370
           +P  V      V A + NP +   L  N ++N V  + ++ F  + K  L       ++ 
Sbjct: 250 LPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILG 309

Query: 371 LLGLSKERKPSVHVVMNLPAKAI 393
           L+  S+E  P    V+   A  I
Sbjct: 310 LIPSSEEGWPIACQVLRQDAGGI 332


>gi|216548193 RAD54-like protein [Homo sapiens]
          Length = 747

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 20/84 (23%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 87  RTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQRPGIRRVIEDPEDKESRLIMLDPYKIF 146
           R+   K   +P+   +  + S+ +       L+R G+RR + DP +K++ L++ +P  + 
Sbjct: 75  RSILSKPFKVPIPNYQGPLGSRAL------GLKRAGVRRALHDPLEKDA-LVLYEPPPLS 127

Query: 147 THDSFEKAELSVLEQLNVSPQISK 170
            HD  +  +  +   + V P +SK
Sbjct: 128 AHDQLKLDKEKLPVHVVVDPILSK 151


>gi|216548186 RAD54-like protein [Homo sapiens]
          Length = 747

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 20/84 (23%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 87  RTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQRPGIRRVIEDPEDKESRLIMLDPYKIF 146
           R+   K   +P+   +  + S+ +       L+R G+RR + DP +K++ L++ +P  + 
Sbjct: 75  RSILSKPFKVPIPNYQGPLGSRAL------GLKRAGVRRALHDPLEKDA-LVLYEPPPLS 127

Query: 147 THDSFEKAELSVLEQLNVSPQISK 170
            HD  +  +  +   + V P +SK
Sbjct: 128 AHDQLKLDKEKLPVHVVVDPILSK 151


>gi|163792194 N2,N2-dimethylguanosine tRNA methyltransferase-like
           [Homo sapiens]
          Length = 733

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 35/119 (29%), Positives = 48/119 (40%), Gaps = 15/119 (12%)

Query: 280 YWNPRLSTEHSRI-------TELLKPGDVLFDVFAGVGPFAIPVAK---KNCTVFANDLN 329
           Y+NP++      I        E  KP + L D F   G   +  AK       V  NDLN
Sbjct: 251 YFNPKMKLNRQLIFCTLAALAEERKPLECL-DAFGATGIMGLQWAKHLGNAVKVTINDLN 309

Query: 330 PESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQGPVKEELMQLLGLSKERKPSVHVVMNL 388
             S   +  NC LNK+   V     +  D     + EE  + LG  K  K   +V+M+L
Sbjct: 310 ENSVTLIQENCHLNKLKVVVDSKEKEKSD----DILEEGEKNLGNIKVTKMDANVLMHL 364


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 16/158 (10%)

Query: 267 ENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGD--VLFDVFAGVGPFAIPV-AKKNCTV 323
           +  YTYE    +V  N R     + I    KP     +F +    G   I + A   C +
Sbjct: 821 QRRYTYERIDGRVRGNLR----QAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCII 876

Query: 324 FANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQGPVKEELMQLLGLSK------E 377
           F +D NP++       C      + VKV+ L  ++  +  + ++    LGL K       
Sbjct: 877 FDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDIN 936

Query: 378 RKPSVHVVMNLPAKAIEFL---SAFKWLLDGQPCSSEF 412
           RK   + V  L    +E L    A+  L+D +   S+F
Sbjct: 937 RKGGTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKF 974


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)

Query: 44   EAPGIFLLGQRKRFSTMPETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRK 103
            + P  + +G   R S    TE+ ++E + FSPPS   G+     T++    NI V K   
Sbjct: 1231 QPPCYYGIGGLWRTSGQEATESAKQEFQHFSPPSGAPGIP----TSYSAYYNISVAKA-- 1284

Query: 104  EIVSKLMRSLKRAALQRPGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQLN 163
            E+++KL    + A +   G   V  +   K+ +LI     K+       +A+  +LE +N
Sbjct: 1285 ELLNKLKDQPEMAEIGL-GEEEVDHELAQKKIQLIESISRKL---SVLREAQRGLLEDIN 1340

Query: 164  VSPQISK 170
             +  + +
Sbjct: 1341 ANSALGE 1347


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
            sapiens]
          Length = 2997

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 10/106 (9%)

Query: 317  AKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQGPVKEELMQLLGLSK 376
            A   C +F +D NP++       C      + VK++ L  ++  +  + ++    LGL K
Sbjct: 1377 AADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDK 1436

Query: 377  E-------RKPSVHVVMNLPAKAIEFL---SAFKWLLDGQPCSSEF 412
                    R+ + + V  L  K IE L    A+  L+D +   S+F
Sbjct: 1437 AVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKF 1482


>gi|169160671 PREDICTED: similar to hCG2039305 [Homo sapiens]
          Length = 219

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 11/65 (16%)

Query: 418 CYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQ 477
           CY  S D N +E VR   G ++ +   A           P +E LC+ F      L KNQ
Sbjct: 166 CYGDSSDKNFSEAVRGSVGVLVTVQCIA----------LPWEEELCLRFMKEVDTLVKNQ 215

Query: 478 TRNPE 482
            R P+
Sbjct: 216 -RGPK 219


>gi|169161659 PREDICTED: similar to hCG2039305 [Homo sapiens]
          Length = 219

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 11/65 (16%)

Query: 418 CYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQ 477
           CY  S D N +E VR   G ++ +   A           P +E LC+ F      L KNQ
Sbjct: 166 CYGDSSDKNFSEAVRGSVGVLVTVQCIA----------LPWEEELCLRFMKEVDTLVKNQ 215

Query: 478 TRNPE 482
            R P+
Sbjct: 216 -RGPK 219


>gi|113408590 PREDICTED: similar to hCG2039305 [Homo sapiens]
          Length = 219

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 11/65 (16%)

Query: 418 CYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQ 477
           CY  S D N +E VR   G ++ +   A           P +E LC+ F      L KNQ
Sbjct: 166 CYGDSSDKNFSEAVRGSVGVLVTVQCIA----------LPWEEELCLRFMKEVDTLVKNQ 215

Query: 478 TRNPE 482
            R P+
Sbjct: 216 -RGPK 219


>gi|47132591 protein kinase N1 isoform 1 [Homo sapiens]
          Length = 948

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 2/58 (3%)

Query: 33  VAWTSLTQMLLEAPGIFLLGQRKRFSTMPETETHERETELFSPPSDVRGMTKLDRTAF 90
           + W +L    L  P +  L  R   S   E  T E  T   SPP D R +T  ++ AF
Sbjct: 883 LGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPT--LSPPRDARPLTAAEQAAF 938


>gi|47132589 protein kinase N1 isoform 2 [Homo sapiens]
          Length = 942

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 2/58 (3%)

Query: 33  VAWTSLTQMLLEAPGIFLLGQRKRFSTMPETETHERETELFSPPSDVRGMTKLDRTAF 90
           + W +L    L  P +  L  R   S   E  T E  T   SPP D R +T  ++ AF
Sbjct: 877 LGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPT--LSPPRDARPLTAAEQAAF 932


>gi|7662230 ring finger protein 40 [Homo sapiens]
          Length = 1001

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 16/101 (15%)

Query: 61  PETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQR 120
           P+ E  ERE     PP     +++ DR   K       ++  K   S+L++ L RA L++
Sbjct: 610 PKRELREREGPSLGPPPVASALSRADREKAK-------VEETKRKESELLKGL-RAELKK 661

Query: 121 PGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQ 161
                     E ++   ++LD YK    +  +K +L   E+
Sbjct: 662 A--------QESQKEMKLLLDMYKSAPKEQRDKVQLMAAER 694


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,060,462
Number of Sequences: 37866
Number of extensions: 823939
Number of successful extensions: 2011
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2002
Number of HSP's gapped (non-prelim): 16
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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