Search of human proteins with 14277682

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14277682 protocadherin gamma subfamily C, 4 isoform 2
precursor [Homo sapiens]
         (871 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs...  1740   0.0  
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs...  1626   0.0  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...   678   0.0  
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...   678   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   607   e-173
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...   607   e-173
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   592   e-169
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...   592   e-169
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   588   e-168
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...   588   e-168
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs...   586   e-167
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   586   e-167
gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs...   585   e-167
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs...   585   e-167
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]       579   e-165
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]       579   e-165
gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs...   579   e-165
gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precurs...   579   e-165
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs...   579   e-165
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs...   579   e-165
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...   578   e-165
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   578   e-165
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs...   577   e-164
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...   577   e-164
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   574   e-163
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs...   574   e-163
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs...   573   e-163
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs...   573   e-163
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   569   e-162
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...   569   e-162

>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 871

 Score = 1740 bits (4507), Expect = 0.0
 Identities = 871/871 (100%), Positives = 871/871 (100%)

Query: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60
           MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS
Sbjct: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60

Query: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120
           ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE
Sbjct: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120

Query: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180
           VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL
Sbjct: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180

Query: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240
           DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP
Sbjct: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240

Query: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300
           AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG
Sbjct: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300

Query: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360
           KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP
Sbjct: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360

Query: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420
           ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS
Sbjct: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420

Query: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480
           YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS
Sbjct: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480

Query: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540
           DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR
Sbjct: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540

Query: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600
           GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS
Sbjct: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600

Query: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660
           GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT
Sbjct: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660

Query: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720
           LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA
Sbjct: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720

Query: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780
           CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT
Sbjct: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780

Query: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEVRPLQAQQMLEGYSDPGIWLGHVLES 840
           RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEVRPLQAQQMLEGYSDPGIWLGHVLES
Sbjct: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEVRPLQAQQMLEGYSDPGIWLGHVLES 840

Query: 841 TGLSVSAHSDVTIFVRGNYVVDAVLCNCFVN 871
           TGLSVSAHSDVTIFVRGNYVVDAVLCNCFVN
Sbjct: 841 TGLSVSAHSDVTIFVRGNYVVDAVLCNCFVN 871


>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 938

 Score = 1626 bits (4211), Expect = 0.0
 Identities = 817/831 (98%), Positives = 817/831 (98%)

Query: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60
           MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS
Sbjct: 1   MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLS 60

Query: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120
           ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE
Sbjct: 61  ARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAE 120

Query: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180
           VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL
Sbjct: 121 VEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFAL 180

Query: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240
           DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP
Sbjct: 181 DVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAP 240

Query: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300
           AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG
Sbjct: 241 AFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTG 300

Query: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360
           KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP
Sbjct: 301 KLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLP 360

Query: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420
           ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS
Sbjct: 361 ESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSS 420

Query: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480
           YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS
Sbjct: 421 YDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAAS 480

Query: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540
           DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR
Sbjct: 481 DPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDR 540

Query: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600
           GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS
Sbjct: 541 GNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDS 600

Query: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660
           GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT
Sbjct: 601 GYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVT 660

Query: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720
           LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA
Sbjct: 661 LLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAA 720

Query: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780
           CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT
Sbjct: 721 CGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPT 780

Query: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEVRPLQAQQMLEGYSDPG 831
           RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLE  P            PG
Sbjct: 781 RSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPG 831


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score =  678 bits (1750), Expect = 0.0
 Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563

Query: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683

Query: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736

Query: 743 LPP---SNGILRIQLGSDDPIKFVDV 765
             P         +Q+ SD  +K+++V
Sbjct: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score =  678 bits (1750), Expect = 0.0
 Identities = 365/746 (48%), Positives = 492/746 (65%), Gaps = 13/746 (1%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G+V GQ+RY V EES+ GT VGNVAQD  L    L +RRLQ+  E N R+F + L SGAL
Sbjct: 25  GWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGAL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
            +   IDRE+LCG S SC++P++ VTE PLE+ R EVEI+D+ND++P F   + ++ I E
Sbjct: 85  AVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
           +A  G RFPL+ AQD DVG+N++S Y LS N HF+L+VK   DG   PEL+LE+ LDRE 
Sbjct: 145 SAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           Q+ ++LVLTAVDGG P RSGT  + V VLD+NDNAP FQ S  R+ + E+AP G +L++L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
           NA+DPD G +G + + F  HT + VRNLF L P++G + +LGP+DFE   +YE   RARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
            G PAME HC ++VD+ DVNDNAP + + S    + ES   GTVV L +V+D DSG NG+
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGE 384

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           VSL I   LPF +K +  N +SL+T+ PLDREA S Y I + ASDAG+P L  H TI LN
Sbjct: 385 VSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLN 443

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ISDVNDN P F Q+ +  ++ EN  PG LLC++AASDPD+G NA ++YS++  + +   A
Sbjct: 444 ISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPA 503

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SSF+ +NP+ G + A R+FDYE  Q LQ  V  RD G+PPL +  ++ +FVLD NDNAPA
Sbjct: 504 SSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPA 563

Query: 565 VLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLL-EAPDPSLFAVSR 623
           VL PR       PQ LP S   G L+TKVTAVD D+G+NAW+SY LL ++  P LF VS 
Sbjct: 564 VLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVST 623

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAP 682
           + GEVRTA   +  D   Q++V++V+D+G P LS++ T+L+ LE++    +P   +    
Sbjct: 624 HTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLIH 683

Query: 683 REGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREG 742
               S LTLYL V+L  +  +S  +F  L +KCL+G A G      G   C    RR++ 
Sbjct: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADG----DGGGGQC---CRRQDS 736

Query: 743 LPP---SNGILRIQLGSDDPIKFVDV 765
             P         +Q+ SD  +K+++V
Sbjct: 737 PSPDFYKQSSPNLQVSSDGTLKYMEV 762


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score =  607 bits (1564), Expect = e-173
 Identities = 330/780 (42%), Positives = 482/780 (61%), Gaps = 12/780 (1%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747

Query: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807


>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score =  607 bits (1564), Expect = e-173
 Identities = 330/780 (42%), Positives = 482/780 (61%), Gaps = 12/780 (1%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568

Query: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628

Query: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688

Query: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747

Query: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  592 bits (1525), Expect = e-169
 Identities = 312/699 (44%), Positives = 457/699 (65%), Gaps = 6/699 (0%)

Query: 18  LFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRV 77
           +FL    G+   QIRY VPEE+++G+FVGN+++D  L+   L+ R +++      + F V
Sbjct: 19  IFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAV 78

Query: 78  DLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQ 137
           +  SG+L+    IDRE LC   +SC + +E + E  L++Y  EVEI+D+ND+AP F   +
Sbjct: 79  NPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDE 138

Query: 138 LDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLE 197
           +++++ E A PG RF L  A+D DVG NS+ SY+LS N +F+L ++ R+DG+  PEL+LE
Sbjct: 139 VEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLE 198

Query: 198 KPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPA 257
             LDREK++ + L+LTA+DGG+P R G   +RV VLDVND+ P F QS YR+SV E+  +
Sbjct: 199 GSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISS 258

Query: 258 GMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYE 317
           G  ++ +NA+DPD G +G V + F  +   +   +F L   TG++ + G LDFE   +YE
Sbjct: 259 GTRVLMVNATDPDEGINGEVMYSFR-NMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYE 317

Query: 318 FDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDP 377
            +++ +DGG   +    ++ + ++DVNDNAP IT+TS + ++ E++ PGTV+AL++VQD 
Sbjct: 318 MEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQ 375

Query: 378 DSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLST 437
           DSG NG VS  IP+HLPF L+  + N + L+T+  LDRE   SY+I +TA+D G+PPLS 
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435

Query: 438 HRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEP 497
              ++LN++D NDNPP F   S+  ++PENN  G  + S+ A DPDS  NAL++YSL + 
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495

Query: 498 RNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLD 557
             + V  SS++S+N  TG ++A +SFDYEQ + L+  V ARD G+PPLSS V++ LFVLD
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLD 555

Query: 558 LNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
            NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P
Sbjct: 556 QNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEP 615

Query: 617 SLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
            LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ D
Sbjct: 616 GLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLAD 675

Query: 676 LRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALLS 713
           L    +    E S L+LYL V++ A+  +     + LL+
Sbjct: 676 LGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLA 714


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score =  592 bits (1525), Expect = e-169
 Identities = 312/699 (44%), Positives = 457/699 (65%), Gaps = 6/699 (0%)

Query: 18  LFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRV 77
           +FL    G+   QIRY VPEE+++G+FVGN+++D  L+   L+ R +++      + F V
Sbjct: 19  IFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAV 78

Query: 78  DLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQ 137
           +  SG+L+    IDRE LC   +SC + +E + E  L++Y  EVEI+D+ND+AP F   +
Sbjct: 79  NPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDE 138

Query: 138 LDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLE 197
           +++++ E A PG RF L  A+D DVG NS+ SY+LS N +F+L ++ R+DG+  PEL+LE
Sbjct: 139 VEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLE 198

Query: 198 KPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPA 257
             LDREK++ + L+LTA+DGG+P R G   +RV VLDVND+ P F QS YR+SV E+  +
Sbjct: 199 GSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISS 258

Query: 258 GMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYE 317
           G  ++ +NA+DPD G +G V + F  +   +   +F L   TG++ + G LDFE   +YE
Sbjct: 259 GTRVLMVNATDPDEGINGEVMYSFR-NMESKASEIFQLDSQTGEVQVRGSLDFEKYRFYE 317

Query: 318 FDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDP 377
            +++ +DGG   +    ++ + ++DVNDNAP IT+TS + ++ E++ PGTV+AL++VQD 
Sbjct: 318 MEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQ 375

Query: 378 DSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLST 437
           DSG NG VS  IP+HLPF L+  + N + L+T+  LDRE   SY+I +TA+D G+PPLS 
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435

Query: 438 HRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEP 497
              ++LN++D NDNPP F   S+  ++PENN  G  + S+ A DPDS  NAL++YSL + 
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495

Query: 498 RNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLD 557
             + V  SS++S+N  TG ++A +SFDYEQ + L+  V ARD G+PPLSS V++ LFVLD
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLD 555

Query: 558 LNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
            NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P
Sbjct: 556 QNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEP 615

Query: 617 SLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
            LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V+ D
Sbjct: 616 GLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLAD 675

Query: 676 LRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALLS 713
           L    +    E S L+LYL V++ A+  +     + LL+
Sbjct: 676 LGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLA 714


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  588 bits (1515), Expect = e-168
 Identities = 305/685 (44%), Positives = 424/685 (61%), Gaps = 3/685 (0%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L   L      I Y +PEE ++G  VGNV  +  LD  SLSARR +V    ++R F 
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V+ ++G + + + +DRE LCG   SC V LE V E PLE++  EV I D+ND+ P FP Q
Sbjct: 79  VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           ++ LEI EA  PG RFPLE A D DVGSNS+ +Y LS NE+FAL V+ R D +   EL+L
Sbjct: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           E+ LDRE++   +LVLTA+DGG P  S +  + + VLD NDNAP F QS YR  VLE AP
Sbjct: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
           +G  ++Q+ A+D D GP+G + + F  H    VR LF+L   TG LT+ G LDFE    +
Sbjct: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
           E  ++A+D G+     HC + V+++DVNDNAP ITVTS    +PE A  GTV+AL+SV D
Sbjct: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            D+G NG V+  +P  LPF+L S+ +N F+L T+  LDRE    Y++ +TA DAG P LS
Sbjct: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
               + + +SD+NDNPP   Q S++V++ ENN PG  + +L+  DPD+  NA +S+ LLE
Sbjct: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                     + ++N   G V +    DYE  +  +      D G P L++ ++V +FV 
Sbjct: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558

Query: 557 DLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
           D NDNAP VL P  RPG    + LP    AGHL+++V   D D+G+NAW+SY LL +P+ 
Sbjct: 559 DRNDNAPQVLYP--RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616

Query: 617 SLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
           SLFA+  + G++ TA P+   D P Q L +++KD+G P LST+ TL VS+ ED+     +
Sbjct: 617 SLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAE 676

Query: 676 LRESSAPREGESRLTLYLAVSLVAI 700
               SAPRE +  LT YL +SL+ +
Sbjct: 677 FPSGSAPREQKKNLTFYLLLSLILV 701


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score =  588 bits (1515), Expect = e-168
 Identities = 305/685 (44%), Positives = 424/685 (61%), Gaps = 3/685 (0%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L   L      I Y +PEE ++G  VGNV  +  LD  SLSARR +V    ++R F 
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFE 78

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V+ ++G + + + +DRE LCG   SC V LE V E PLE++  EV I D+ND+ P FP Q
Sbjct: 79  VNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQ 138

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
           ++ LEI EA  PG RFPLE A D DVGSNS+ +Y LS NE+FAL V+ R D +   EL+L
Sbjct: 139 EMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVL 198

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           E+ LDRE++   +LVLTA+DGG P  S +  + + VLD NDNAP F QS YR  VLE AP
Sbjct: 199 ERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAP 258

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
           +G  ++Q+ A+D D GP+G + + F  H    VR LF+L   TG LT+ G LDFE    +
Sbjct: 259 SGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLH 318

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
           E  ++A+D G+     HC + V+++DVNDNAP ITVTS    +PE A  GTV+AL+SV D
Sbjct: 319 EIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTD 378

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            D+G NG V+  +P  LPF+L S+ +N F+L T+  LDRE    Y++ +TA DAG P LS
Sbjct: 379 LDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLS 438

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
               + + +SD+NDNPP   Q S++V++ ENN PG  + +L+  DPD+  NA +S+ LLE
Sbjct: 439 ALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLE 498

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                     + ++N   G V +    DYE  +  +      D G P L++ ++V +FV 
Sbjct: 499 QGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVT 558

Query: 557 DLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDP 616
           D NDNAP VL P  RPG    + LP    AGHL+++V   D D+G+NAW+SY LL +P+ 
Sbjct: 559 DRNDNAPQVLYP--RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616

Query: 617 SLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD 675
           SLFA+  + G++ TA P+   D P Q L +++KD+G P LST+ TL VS+ ED+     +
Sbjct: 617 SLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAE 676

Query: 676 LRESSAPREGESRLTLYLAVSLVAI 700
               SAPRE +  LT YL +SL+ +
Sbjct: 677 FPSGSAPREQKKNLTFYLLLSLILV 701


>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  586 bits (1511), Expect = e-167
 Identities = 318/693 (45%), Positives = 442/693 (63%), Gaps = 10/693 (1%)

Query: 30  QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKNP 89
           QI Y V EE +EG+ VGN+A+D  L    L+ R +++      + F ++  SG L+    
Sbjct: 30  QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89

Query: 90  IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
           IDRE LC  S +C+  LE + E  +++ R EVEI+DVND+ P F  +Q ++++ E   PG
Sbjct: 90  IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149

Query: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
            RFPL +A D DVG NS+  Y+L+SN +F+LDV+  +DG   PEL+LE+ LDRE+++ + 
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209

Query: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
           LVLTA DGG+P RSGTA + + ++D NDNAP F Q  Y +SV E+ P G  L+ + A+DP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269

Query: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
           D G +G+VT+ F     D++  LF L+  +G +T+LG LD+E   +Y+ DV A DG  P 
Sbjct: 270 DEGANGDVTYSFR-KVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDG--PG 326

Query: 330 MEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLRI 389
           +     + V +LD NDNAP +TVTS   ++ ES+ PGTV+AL +V D DSG NG V+  I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386

Query: 390 PDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVN 449
           PD+LPF L+  + N + L+T   LDRE  S Y+I VTA+D G PPLST   I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446

Query: 450 DNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFIS 509
           DNPP+F   S+  ++PENN  G  + S+ A DPDSG NA I+YSL E   +    SS++S
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506

Query: 510 LNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
           +N  TG ++A  SFDYEQ + LQ  + A D G+PPLSS V++ LFVLD NDN P +L P 
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566

Query: 570 -ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEV 628
               GS   +  P S  +G+L+TKV AVD DSG NAW+SY LL++ +P LFAV  + GEV
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEV 626

Query: 629 RTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD---LRESSAPRE 684
           RTA   +  D   Q+LV+VV+D G PPLS +VTL V++ +    V+ D   L+ S+ P  
Sbjct: 627 RTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADP-- 684

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
            +S LTLYL V++ A+  V       LL+  LR
Sbjct: 685 DDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLR 717


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  586 bits (1511), Expect = e-167
 Identities = 318/693 (45%), Positives = 442/693 (63%), Gaps = 10/693 (1%)

Query: 30  QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKNP 89
           QI Y V EE +EG+ VGN+A+D  L    L+ R +++      + F ++  SG L+    
Sbjct: 30  QILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSGTLVTAGR 89

Query: 90  IDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPG 149
           IDRE LC  S +C+  LE + E  +++ R EVEI+DVND+ P F  +Q ++++ E   PG
Sbjct: 90  IDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPG 149

Query: 150 QRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYR 209
            RFPL +A D DVG NS+  Y+L+SN +F+LDV+  +DG   PEL+LE+ LDRE+++ + 
Sbjct: 150 ARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHH 209

Query: 210 LVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDP 269
           LVLTA DGG+P RSGTA + + ++D NDNAP F Q  Y +SV E+ P G  L+ + A+DP
Sbjct: 210 LVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDP 269

Query: 270 DLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPA 329
           D G +G+VT+ F     D++  LF L+  +G +T+LG LD+E   +Y+ DV A DG  P 
Sbjct: 270 DEGANGDVTYSFR-KVRDKISQLFQLNSLSGDITILGGLDYEDSGFYDIDVEAHDG--PG 326

Query: 330 MEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLRI 389
           +     + V +LD NDNAP +TVTS   ++ ES+ PGTV+AL +V D DSG NG V+  I
Sbjct: 327 LRARSKVLVTVLDENDNAPEVTVTSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSI 386

Query: 390 PDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVN 449
           PD+LPF L+  + N + L+T   LDRE  S Y+I VTA+D G PPLST   I L + D+N
Sbjct: 387 PDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNITVTATDQGTPPLSTETHISLQVMDIN 446

Query: 450 DNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFIS 509
           DNPP+F   S+  ++PENN  G  + S+ A DPDSG NA I+YSL E   +    SS++S
Sbjct: 447 DNPPTFPHASYSAYIPENNPRGASILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVS 506

Query: 510 LNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
           +N  TG ++A  SFDYEQ + LQ  + A D G+PPLSS V++ LFVLD NDN P +L P 
Sbjct: 507 INSNTGILYALCSFDYEQFRDLQLLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPT 566

Query: 570 -ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEV 628
               GS   +  P S  +G+L+TKV AVD DSG NAW+SY LL++ +P LFAV  + GEV
Sbjct: 567 FPTDGSTGVELAPRSADSGYLVTKVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEV 626

Query: 629 RTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPD---LRESSAPRE 684
           RTA   +  D   Q+LV+VV+D G PPLS +VTL V++ +    V+ D   L+ S+ P  
Sbjct: 627 RTARALLDRDALKQRLVVVVQDHGQPPLSATVTLTVAVADSIPDVLADLGSLKPSADP-- 684

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
            +S LTLYL V++ A+  V       LL+  LR
Sbjct: 685 DDSGLTLYLVVAVAAVSCVFLAFVTVLLALKLR 717


>gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  585 bits (1509), Expect = e-167
 Identities = 304/709 (42%), Positives = 444/709 (62%), Gaps = 13/709 (1%)

Query: 27  VCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLI 86
           +C QIRY +PEE  +G+ VGN+A D       L  R+L+V+ E  + +F V  +SG LL+
Sbjct: 29  LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSE--KPYFTVSAESGELLV 86

Query: 87  KNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAA 146
            + +DRE +CG   +C +  E V E PL  Y   VEI D+NDH P+F +   +L+I E+A
Sbjct: 87  SSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESA 146

Query: 147 PPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQS 206
            PG RF LE A+DAD+G NS+  Y+LS N  F+L +K++ DGS  PEL LEK LDRE+QS
Sbjct: 147 QPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQS 206

Query: 207 DYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNA 266
            +RLVLTA+DGG+PP SGT ELR+ V D NDN P F +  YR+S+ E+ P G  ++Q++A
Sbjct: 207 YHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSA 266

Query: 267 SDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGG 326
           +D D G +  +T+ F      R   +FSL+  +G++T    LDFE    Y   V  RDGG
Sbjct: 267 TDQDEGINSEITYSFY-----RTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGG 321

Query: 327 SPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVS 386
              +   C++ +++ D NDN+P +T  S L  + E+A PGT++ALI + D DSG NG+V+
Sbjct: 322 G--LVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379

Query: 387 LRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
            ++   +PF + S+ +N + LVT G LDRE    Y++ +TA+D G PPLS+  ++ L+I 
Sbjct: 380 CQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIR 439

Query: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
           DVNDN P F Q S+ V VPENN PG  +  + ASD D GLN  +SYS++      ++ +S
Sbjct: 440 DVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALAS 499

Query: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
           ++S++ Q+G V A R+FDYEQ +T +  +QARD+G+P LS+ V++R+ V D NDNAP VL
Sbjct: 500 YVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL 559

Query: 567 RPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYA 625
            P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +P LF++    
Sbjct: 560 YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRT 619

Query: 626 GEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPRE 684
           GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+PD+ +   P +
Sbjct: 620 GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSD 679

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLR--GAACGVTCFPAGTC 731
            ++ L  YL V+L  I  +   + +  ++  LR   +    +CF  G C
Sbjct: 680 PQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAWSCFQPGLC 728


>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score =  585 bits (1509), Expect = e-167
 Identities = 304/709 (42%), Positives = 444/709 (62%), Gaps = 13/709 (1%)

Query: 27  VCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLI 86
           +C QIRY +PEE  +G+ VGN+A D       L  R+L+V+ E  + +F V  +SG LL+
Sbjct: 29  LCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSE--KPYFTVSAESGELLV 86

Query: 87  KNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAA 146
            + +DRE +CG   +C +  E V E PL  Y   VEI D+NDH P+F +   +L+I E+A
Sbjct: 87  SSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESA 146

Query: 147 PPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQS 206
            PG RF LE A+DAD+G NS+  Y+LS N  F+L +K++ DGS  PEL LEK LDRE+QS
Sbjct: 147 QPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQS 206

Query: 207 DYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNA 266
            +RLVLTA+DGG+PP SGT ELR+ V D NDN P F +  YR+S+ E+ P G  ++Q++A
Sbjct: 207 YHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSA 266

Query: 267 SDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGG 326
           +D D G +  +T+ F      R   +FSL+  +G++T    LDFE    Y   V  RDGG
Sbjct: 267 TDQDEGINSEITYSFY-----RTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGG 321

Query: 327 SPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVS 386
              +   C++ +++ D NDN+P +T  S L  + E+A PGT++ALI + D DSG NG+V+
Sbjct: 322 G--LVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379

Query: 387 LRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNIS 446
            ++   +PF + S+ +N + LVT G LDRE    Y++ +TA+D G PPLS+  ++ L+I 
Sbjct: 380 CQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIR 439

Query: 447 DVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASS 506
           DVNDN P F Q S+ V VPENN PG  +  + ASD D GLN  +SYS++      ++ +S
Sbjct: 440 DVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALAS 499

Query: 507 FISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVL 566
           ++S++ Q+G V A R+FDYEQ +T +  +QARD+G+P LS+ V++R+ V D NDNAP VL
Sbjct: 500 YVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL 559

Query: 567 RPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYA 625
            P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +P LF++    
Sbjct: 560 YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRT 619

Query: 626 GEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPRE 684
           GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+PD+ +   P +
Sbjct: 620 GEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSD 679

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLR--GAACGVTCFPAGTC 731
            ++ L  YL V+L  I  +   + +  ++  LR   +    +CF  G C
Sbjct: 680 PQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAWSCFQPGLC 728


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score =  579 bits (1492), Expect = e-165
 Identities = 334/840 (39%), Positives = 484/840 (57%), Gaps = 65/840 (7%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           L  L + +  V  Q+ Y V EE + GTFVGN+A+D  LD   LSAR  Q        +  
Sbjct: 6   LFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLD 65

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           ++L++G L +   IDRE +C  S SC++ LE   E PLE+++ E+E++D+ND+ P FP  
Sbjct: 66  LNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEP 125

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            L +EI E+A PG RFPLE A D DVG+NS+  Y ++ N +F+LDV+ + DG+   EL+L
Sbjct: 126 DLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVL 185

Query: 197 EKPLDREKQSDYRLVLTAVDGGN----------------PP---RSGTAELRVSVLDVND 237
           EKPLDRE+Q+ +R VLTAVDGG                 PP   R+GTA L + VLD ND
Sbjct: 186 EKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSND 245

Query: 238 NAPAFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHP 297
           N PAF Q  Y +S+ E++P G ++IQLNA+DPD G +G V + FS H   R R LF L P
Sbjct: 246 NVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSP 305

Query: 298 TTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELG 357
            TG+L + G LD+E    Y+  V+A+D G  A+  HC + V +LD NDNAP I+ ++   
Sbjct: 306 RTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKE 365

Query: 358 TLPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREA 417
            + E A PGTVVAL SV D DS  NG V   +   +PF LKS+F+N +++VT  PLDREA
Sbjct: 366 AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREA 425

Query: 418 KSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSL 477
             SY + V A D G P LST ++I + +SDVNDN P F Q  ++V+V ENN PG  + ++
Sbjct: 426 GDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAV 485

Query: 478 AASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQA 537
           +A+D D G NA ++YS+LE + + +S  +++S+N + G ++A RSFDYEQ +   F+V+A
Sbjct: 486 SATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEA 545

Query: 538 RDRGNP-PLSSTVTVRLFVLDLNDNAPAVLRP-RARPGSLCPQALPPSVGAGHLITKVTA 595
           RD G+P  L+   TV + ++D NDNAPA++ P   R G+   + LP S   G+L+T+V A
Sbjct: 546 RDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAA 605

Query: 596 VDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQK---LVIVVKDSGS 652
           VD D G NA ++Y ++   + +LF +    GE+RTA  +PA   PQ+   LVI V+D G 
Sbjct: 606 VDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQ 665

Query: 653 PPLSTSVTLLVSLEEDTHPVVP------------DLRESSAPREGESR--LTLYLAVSLV 698
           PPLS++ TL+V L +    V P            + +  S    GE+   LTL L ++L 
Sbjct: 666 PPLSSTATLVVQLVDGA--VEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALG 723

Query: 699 AICFVSFGSFVALLSKCLRG-------------AACGVTCFPAGTCACLTRSRRREGLPP 745
           ++ F+   + + L  +C +                C   C   G+  C  ++R R+    
Sbjct: 724 SVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLS 783

Query: 746 SNGILRIQLGSDDPIKFVDV--------GGHSHG---CTPLASAPTRSDSFMMVKSPSAP 794
            + I+ +Q  S+ P     V        G H H    C  +   P  + + +M   P +P
Sbjct: 784 KSDIMLVQ-SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSP 842


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score =  579 bits (1492), Expect = e-165
 Identities = 334/840 (39%), Positives = 484/840 (57%), Gaps = 65/840 (7%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           L  L + +  V  Q+ Y V EE + GTFVGN+A+D  LD   LSAR  Q        +  
Sbjct: 6   LFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLD 65

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           ++L++G L +   IDRE +C  S SC++ LE   E PLE+++ E+E++D+ND+ P FP  
Sbjct: 66  LNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEP 125

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            L +EI E+A PG RFPLE A D DVG+NS+  Y ++ N +F+LDV+ + DG+   EL+L
Sbjct: 126 DLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVL 185

Query: 197 EKPLDREKQSDYRLVLTAVDGGN----------------PP---RSGTAELRVSVLDVND 237
           EKPLDRE+Q+ +R VLTAVDGG                 PP   R+GTA L + VLD ND
Sbjct: 186 EKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSND 245

Query: 238 NAPAFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHP 297
           N PAF Q  Y +S+ E++P G ++IQLNA+DPD G +G V + FS H   R R LF L P
Sbjct: 246 NVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSP 305

Query: 298 TTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELG 357
            TG+L + G LD+E    Y+  V+A+D G  A+  HC + V +LD NDNAP I+ ++   
Sbjct: 306 RTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKE 365

Query: 358 TLPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREA 417
            + E A PGTVVAL SV D DS  NG V   +   +PF LKS+F+N +++VT  PLDREA
Sbjct: 366 AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREA 425

Query: 418 KSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSL 477
             SY + V A D G P LST ++I + +SDVNDN P F Q  ++V+V ENN PG  + ++
Sbjct: 426 GDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAV 485

Query: 478 AASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQA 537
           +A+D D G NA ++YS+LE + + +S  +++S+N + G ++A RSFDYEQ +   F+V+A
Sbjct: 486 SATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEA 545

Query: 538 RDRGNP-PLSSTVTVRLFVLDLNDNAPAVLRP-RARPGSLCPQALPPSVGAGHLITKVTA 595
           RD G+P  L+   TV + ++D NDNAPA++ P   R G+   + LP S   G+L+T+V A
Sbjct: 546 RDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAA 605

Query: 596 VDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQK---LVIVVKDSGS 652
           VD D G NA ++Y ++   + +LF +    GE+RTA  +PA   PQ+   LVI V+D G 
Sbjct: 606 VDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQ 665

Query: 653 PPLSTSVTLLVSLEEDTHPVVP------------DLRESSAPREGESR--LTLYLAVSLV 698
           PPLS++ TL+V L +    V P            + +  S    GE+   LTL L ++L 
Sbjct: 666 PPLSSTATLVVQLVDGA--VEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALG 723

Query: 699 AICFVSFGSFVALLSKCLRG-------------AACGVTCFPAGTCACLTRSRRREGLPP 745
           ++ F+   + + L  +C +                C   C   G+  C  ++R R+    
Sbjct: 724 SVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLS 783

Query: 746 SNGILRIQLGSDDPIKFVDV--------GGHSHG---CTPLASAPTRSDSFMMVKSPSAP 794
            + I+ +Q  S+ P     V        G H H    C  +   P  + + +M   P +P
Sbjct: 784 KSDIMLVQ-SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSP 842


>gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 963

 Score =  579 bits (1492), Expect = e-165
 Identities = 315/715 (44%), Positives = 438/715 (61%), Gaps = 10/715 (1%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L+   G   GQ+ Y VPEE++ G  VGN++ D  L   ++S+R  +      + +F 
Sbjct: 8   VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           VDL SG L+++ P DRE LC   A+C++  + V E PLE+++  + ++D ND++P FP  
Sbjct: 68  VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            + L I E   PG RF L  AQD D GSN I SY LS ++HF LD+  R DGS  PEL+L
Sbjct: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR  V E+AP
Sbjct: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313
            G VL ++ A DPD G +G V +  S  T   +R+ F +HP +G++ +   LGP +   E
Sbjct: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307

Query: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373
            Y E    ARD G   +     L V++ DVND+AP +   +    +PE A PGTV+AL S
Sbjct: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363

Query: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433
           V+D D  SNG V   +    PF L ++F N +SL+  GPLDRE  S Y +++TASD+G+P
Sbjct: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423

Query: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493
           PLST RTI ++++DVNDN P+F Q   E+FV ENN PG  L  + A DPD G N L+SY 
Sbjct: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483

Query: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553
           LL+  +   SASS +++   +GA+ A  SFD+EQ +   F+V+ RD G PP S+TVT+ L
Sbjct: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543

Query: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
           FV+D NDN P +L P  R GS+  + +P S   GHL+TKV A D DSG NAW+SY +  A
Sbjct: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603

Query: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
            D SLF +S   GE+RTA + +P D   Q++V+VV+D G PPLS+SVTL V L      +
Sbjct: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663

Query: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGA--ACGVTC 725
           +PD  +   P    S   LYL ++L  I F+  G  +  +   L  +   C  +C
Sbjct: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSC 718


>gi|14717403 protocadherin alpha subfamily C, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  579 bits (1492), Expect = e-165
 Identities = 315/715 (44%), Positives = 438/715 (61%), Gaps = 10/715 (1%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           +L L+   G   GQ+ Y VPEE++ G  VGN++ D  L   ++S+R  +      + +F 
Sbjct: 8   VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           VDL SG L+++ P DRE LC   A+C++  + V E PLE+++  + ++D ND++P FP  
Sbjct: 68  VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            + L I E   PG RF L  AQD D GSN I SY LS ++HF LD+  R DGS  PEL+L
Sbjct: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EK LDRE+++ + LVLTA DGG P RSG A++ + V+D NDNAP F++S YR  V E+AP
Sbjct: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTL---LGPLDFESE 313
            G VL ++ A DPD G +G V +  S  T   +R+ F +HP +G++ +   LGP +   E
Sbjct: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLE 307

Query: 314 NYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALIS 373
            Y E    ARD G   +     L V++ DVND+AP +   +    +PE A PGTV+AL S
Sbjct: 308 AYIE----ARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFS 363

Query: 374 VQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNP 433
           V+D D  SNG V   +    PF L ++F N +SL+  GPLDRE  S Y +++TASD+G+P
Sbjct: 364 VKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSP 423

Query: 434 PLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYS 493
           PLST RTI ++++DVNDN P+F Q   E+FV ENN PG  L  + A DPD G N L+SY 
Sbjct: 424 PLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYE 483

Query: 494 LLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRL 553
           LL+  +   SASS +++   +GA+ A  SFD+EQ +   F+V+ RD G PP S+TVT+ L
Sbjct: 484 LLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINL 543

Query: 554 FVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
           FV+D NDN P +L P  R GS+  + +P S   GHL+TKV A D DSG NAW+SY +  A
Sbjct: 544 FVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRA 603

Query: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
            D SLF +S   GE+RTA + +P D   Q++V+VV+D G PPLS+SVTL V L      +
Sbjct: 604 SDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQL 663

Query: 673 VPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGA--ACGVTC 725
           +PD  +   P    S   LYL ++L  I F+  G  +  +   L  +   C  +C
Sbjct: 664 LPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSC 718


>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 813

 Score =  579 bits (1492), Expect = e-165
 Identities = 321/713 (45%), Positives = 442/713 (61%), Gaps = 10/713 (1%)

Query: 12  WRWATLLFLFYHLGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVA 67
           W    LL  F  LG +C    GQIRY +PEE  +G+FVGN+A+D  L+   L+ R +++ 
Sbjct: 8   WGCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIV 67

Query: 68  GEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVN 127
                + F ++  SG+L+    IDRE LC  S  C+V    + E  +++Y  EVEI+D+N
Sbjct: 68  SRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIN 127

Query: 128 DHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSD 187
           D+ PRF  ++L +++ E A  G R  L  A+DADVG NS+ SY+LSSN HF+LDV   +D
Sbjct: 128 DNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTD 187

Query: 188 GSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSY 247
           G   PEL+LE+PLDREK++ + L+LTA+DGG+P  SGT  +RV+VLD NDNAP F  S Y
Sbjct: 188 GQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEY 247

Query: 248 RISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGP 307
            +SV E+ P G  L+ L A+DPD G +G +T+ F  +  +++   F L    G+++ L  
Sbjct: 248 SVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFR-NEEEKISETFQLDSNLGEISTLQS 306

Query: 308 LDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGT 367
           LD+E   +Y  +V A+DGG  A+     + V + DVNDNAP + +TS   ++ E   PGT
Sbjct: 307 LDYEESRFYLMEVVAQDGG--ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGT 364

Query: 368 VVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
           V+AL SV D DSG NG+++  IP +LPF L+ +  N + L+T   LDRE  S Y+I +T 
Sbjct: 365 VIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTV 424

Query: 428 SDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLN 487
            D G PPLST   I L ++DVNDNPP+F Q S+   V ENN  G  + S+ A DPDSG N
Sbjct: 425 MDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDN 484

Query: 488 ALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSS 547
           A ++YSL E   +    SS++S+N  TG ++A RSFDYEQ + LQ  V A D GNPPLSS
Sbjct: 485 ARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSS 544

Query: 548 TVTVRLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWV 606
            V++ LFVLD NDN P +L P     GS   +  P S   G+L+TKV AVD DSG NAW+
Sbjct: 545 NVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWL 604

Query: 607 SYQLLEAPDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSL 665
           SY+LL+A +P LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS + T+ V++
Sbjct: 605 SYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAV 664

Query: 666 EEDTHPVVPDLRESSAPREGES-RLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
            +    ++ DL     P + E   LTLYL V++ A+  V     + LL   LR
Sbjct: 665 ADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLR 717


>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  579 bits (1492), Expect = e-165
 Identities = 321/713 (45%), Positives = 442/713 (61%), Gaps = 10/713 (1%)

Query: 12  WRWATLLFLFYHLGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVA 67
           W    LL  F  LG +C    GQIRY +PEE  +G+FVGN+A+D  L+   L+ R +++ 
Sbjct: 8   WGCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIV 67

Query: 68  GEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVN 127
                + F ++  SG+L+    IDRE LC  S  C+V    + E  +++Y  EVEI+D+N
Sbjct: 68  SRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDIN 127

Query: 128 DHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSD 187
           D+ PRF  ++L +++ E A  G R  L  A+DADVG NS+ SY+LSSN HF+LDV   +D
Sbjct: 128 DNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTD 187

Query: 188 GSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSY 247
           G   PEL+LE+PLDREK++ + L+LTA+DGG+P  SGT  +RV+VLD NDNAP F  S Y
Sbjct: 188 GQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEY 247

Query: 248 RISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGP 307
            +SV E+ P G  L+ L A+DPD G +G +T+ F  +  +++   F L    G+++ L  
Sbjct: 248 SVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFR-NEEEKISETFQLDSNLGEISTLQS 306

Query: 308 LDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGT 367
           LD+E   +Y  +V A+DGG  A+     + V + DVNDNAP + +TS   ++ E   PGT
Sbjct: 307 LDYEESRFYLMEVVAQDGG--ALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGT 364

Query: 368 VVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTA 427
           V+AL SV D DSG NG+++  IP +LPF L+ +  N + L+T   LDRE  S Y+I +T 
Sbjct: 365 VIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTV 424

Query: 428 SDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLN 487
            D G PPLST   I L ++DVNDNPP+F Q S+   V ENN  G  + S+ A DPDSG N
Sbjct: 425 MDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDN 484

Query: 488 ALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSS 547
           A ++YSL E   +    SS++S+N  TG ++A RSFDYEQ + LQ  V A D GNPPLSS
Sbjct: 485 ARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSS 544

Query: 548 TVTVRLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWV 606
            V++ LFVLD NDN P +L P     GS   +  P S   G+L+TKV AVD DSG NAW+
Sbjct: 545 NVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWL 604

Query: 607 SYQLLEAPDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSL 665
           SY+LL+A +P LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS + T+ V++
Sbjct: 605 SYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAV 664

Query: 666 EEDTHPVVPDLRESSAPREGES-RLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
            +    ++ DL     P + E   LTLYL V++ A+  V     + LL   LR
Sbjct: 665 ADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLR 717


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score =  578 bits (1490), Expect = e-165
 Identities = 316/697 (45%), Positives = 441/697 (63%), Gaps = 4/697 (0%)

Query: 12  WRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVN 71
           WR   LL L        GQ+ Y VPEE++ GTFVG +AQD  L+   L  R  +VA + +
Sbjct: 12  WRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71

Query: 72  QRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAP 131
           +    V L +G L + + IDRE LCG SA C + LE + + PL+++  +VE+ DVND+ P
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131

Query: 132 RFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLV 191
            F  +   L + E+  P  RFPLE A DADVG+NS+ +YRLSS+++F LDV  ++D + +
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191

Query: 192 PELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISV 251
            EL+L K LDRE    + L LTA DGG P  +GT +L V+VLDVNDNAP F+QS Y + +
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 LESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFE 311
            E+A  G  +I+LNASDPD G +G +++ F+      V + FS+   TG++ + G LDFE
Sbjct: 252 FENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 SENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVAL 371
            EN Y+  + A D G P M  HC++ V +LD NDN P I +TS    + E A+ GTV+AL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAG 431
           ISV D DSG+NG V+  +  H+PF L S F+N +SLV    LDRE  S+Y+++VTA D G
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431

Query: 432 NPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALIS 491
           +P L    ++ + ++DVNDN P+F Q  + VFV ENN PG  + +++A D D+  NAL+S
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTV 551
           YSL+E R  + S SS+IS++ ++G V+A +  D+E+ + LQF+V ARD G PPL S VT+
Sbjct: 492 YSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 RLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQL 610
           ++FVLD NDNAPA+L PR    G    + +P SVGAGH++ KV AVD DSGYNAW+SY+L
Sbjct: 552 QVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 611 L-EAPDPSL-FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEE 667
              A  P + F V  Y GE+ T  V   AD P  +L+++VKD G P L+ + T+LVSL E
Sbjct: 612 QPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 668 DTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVS 704
                    R+S+     E+ L       ++AIC VS
Sbjct: 672 SGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVS 708


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  578 bits (1490), Expect = e-165
 Identities = 316/697 (45%), Positives = 441/697 (63%), Gaps = 4/697 (0%)

Query: 12  WRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVN 71
           WR   LL L        GQ+ Y VPEE++ GTFVG +AQD  L+   L  R  +VA + +
Sbjct: 12  WRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71

Query: 72  QRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAP 131
           +    V L +G L + + IDRE LCG SA C + LE + + PL+++  +VE+ DVND+ P
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131

Query: 132 RFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLV 191
            F  +   L + E+  P  RFPLE A DADVG+NS+ +YRLSS+++F LDV  ++D + +
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191

Query: 192 PELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISV 251
            EL+L K LDRE    + L LTA DGG P  +GT +L V+VLDVNDNAP F+QS Y + +
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 LESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFE 311
            E+A  G  +I+LNASDPD G +G +++ F+      V + FS+   TG++ + G LDFE
Sbjct: 252 FENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 SENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVAL 371
            EN Y+  + A D G P M  HC++ V +LD NDN P I +TS    + E A+ GTV+AL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAG 431
           ISV D DSG+NG V+  +  H+PF L S F+N +SLV    LDRE  S+Y+++VTA D G
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431

Query: 432 NPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALIS 491
           +P L    ++ + ++DVNDN P+F Q  + VFV ENN PG  + +++A D D+  NAL+S
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTV 551
           YSL+E R  + S SS+IS++ ++G V+A +  D+E+ + LQF+V ARD G PPL S VT+
Sbjct: 492 YSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 RLFVLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQL 610
           ++FVLD NDNAPA+L PR    G    + +P SVGAGH++ KV AVD DSGYNAW+SY+L
Sbjct: 552 QVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 611 L-EAPDPSL-FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEE 667
              A  P + F V  Y GE+ T  V   AD P  +L+++VKD G P L+ + T+LVSL E
Sbjct: 612 QPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 668 DTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVS 704
                    R+S+     E+ L       ++AIC VS
Sbjct: 672 SGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVS 708


>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 810

 Score =  577 bits (1488), Expect = e-164
 Identities = 314/735 (42%), Positives = 454/735 (61%), Gaps = 18/735 (2%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LL LF   G +  QIRY +PEE   G+ VG +A+D  L    L  R+L+V+ E    +F 
Sbjct: 19  LLSLF--CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE---DYFN 73

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V L+SG LL+   IDRE +CG    C +  E V E P+ ++   V I D+ND+APRF  +
Sbjct: 74  VSLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAK 133

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            +DLEI E+A PG +F L+ AQDADV  NS+  Y ++ N++F+L  K+  DGS  P LLL
Sbjct: 134 GIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLL 193

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EKPLDRE QS +RL+LTA+DGG+PP SGT  + + V D NDNAP F Q  YR+S+ E+ P
Sbjct: 194 EKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVP 253

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
            G  ++++ A+D D G +  +T+ F         +LF+L+P TG +T  G LDFE  + Y
Sbjct: 254 WGTSVLRVMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRY 311

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
              V A+DGG      HC+++++++D NDNAP +T  S    +PE ++ GTV+ALI V+D
Sbjct: 312 VLSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRD 369

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            DSG NG V+    + +PF L+S  +N + LV AG L+RE  + Y++ + A+D G P LS
Sbjct: 370 KDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALS 429

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
           +  +I L+ISD+NDN P F Q S+ V V ENN PG  +  ++ASDPD G N  +SYS+L 
Sbjct: 430 SRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILA 489

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                    S++S++PQ+G V A R+FD+EQ +  +  +QARD+G+P LS+ V++R+ V 
Sbjct: 490 SDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVG 549

Query: 557 DLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPD 615
           DLNDNAP VL P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +
Sbjct: 550 DLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASE 609

Query: 616 PSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVP 674
           P LF++    GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669

Query: 675 DLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCA 732
           DL +   P + ++ L  YL V+L  I  +   + +  ++  LR ++   T  CF  G C 
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLC- 728

Query: 733 CLTRSRRREGLPPSN 747
               S+   G+PP++
Sbjct: 729 ----SKSGPGVPPNH 739


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score =  577 bits (1488), Expect = e-164
 Identities = 314/735 (42%), Positives = 454/735 (61%), Gaps = 18/735 (2%)

Query: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFR 76
           LL LF   G +  QIRY +PEE   G+ VG +A+D  L    L  R+L+V+ E    +F 
Sbjct: 19  LLSLF--CGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE---DYFN 73

Query: 77  VDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQ 136
           V L+SG LL+   IDRE +CG    C +  E V E P+ ++   V I D+ND+APRF  +
Sbjct: 74  VSLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAK 133

Query: 137 QLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLL 196
            +DLEI E+A PG +F L+ AQDADV  NS+  Y ++ N++F+L  K+  DGS  P LLL
Sbjct: 134 GIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLL 193

Query: 197 EKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAP 256
           EKPLDRE QS +RL+LTA+DGG+PP SGT  + + V D NDNAP F Q  YR+S+ E+ P
Sbjct: 194 EKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQENVP 253

Query: 257 AGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYY 316
            G  ++++ A+D D G +  +T+ F         +LF+L+P TG +T  G LDFE  + Y
Sbjct: 254 WGTSVLRVMATDQDEGINAEITYAFLNSPIST--SLFNLNPNTGDITTNGTLDFEETSRY 311

Query: 317 EFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQD 376
              V A+DGG      HC+++++++D NDNAP +T  S    +PE ++ GTV+ALI V+D
Sbjct: 312 VLSVEAKDGG--VHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRD 369

Query: 377 PDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLS 436
            DSG NG V+    + +PF L+S  +N + LV AG L+RE  + Y++ + A+D G P LS
Sbjct: 370 KDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALS 429

Query: 437 THRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLE 496
           +  +I L+ISD+NDN P F Q S+ V V ENN PG  +  ++ASDPD G N  +SYS+L 
Sbjct: 430 SRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILA 489

Query: 497 PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVL 556
                    S++S++PQ+G V A R+FD+EQ +  +  +QARD+G+P LS+ V++R+ V 
Sbjct: 490 SDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVG 549

Query: 557 DLNDNAPAVLRPRARP-GSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPD 615
           DLNDNAP VL P   P GS     +P +   G+L+TKV AVD DSG+NAW+SY +L+A +
Sbjct: 550 DLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASE 609

Query: 616 PSLFAVSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVP 674
           P LF++    GEVRTA  +   D   Q+L++ V+D G PPLS + TL +   +    V+P
Sbjct: 610 PGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLP 669

Query: 675 DLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVT--CFPAGTCA 732
           DL +   P + ++ L  YL V+L  I  +   + +  ++  LR ++   T  CF  G C 
Sbjct: 670 DLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTEGCFQTGLC- 728

Query: 733 CLTRSRRREGLPPSN 747
               S+   G+PP++
Sbjct: 729 ----SKSGPGVPPNH 739


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  574 bits (1480), Expect = e-163
 Identities = 312/692 (45%), Positives = 432/692 (62%), Gaps = 6/692 (0%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G    QIRY +PEE ++G+FVGN+ +D  L+   L+   +++      + F ++  +G+L
Sbjct: 25  GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNPRNGSL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
           +    IDRE LC  S  C+V    + E  L +Y  EVEIVD+ND+ PRF +++L+++I E
Sbjct: 85  VTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELEVKILE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
            A P  RFPL +  D DVG NS+  ++LS N HF++DV+  + G   PEL+LE  LDRE 
Sbjct: 145 NAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGTLDREG 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           ++ YRLVLTA+DGG+P RS  A++ V+VLDVNDN P F Q  YR+SV E+ P G  ++ +
Sbjct: 205 EAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGTPVLAV 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
            A+D D G  G VT+ F   T +++  +F L+  TG+++    LD+E  ++YE  V ARD
Sbjct: 265 TATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYEDSSFYELGVEARD 323

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
           G  P +     + + +LDVNDN P + VTS   T+ ESA PGTV+AL  V D DSG NG 
Sbjct: 324 G--PGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDSGLNGL 381

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           V+  IP  LPF L+ +  N + LVT   LDRE    Y+I VTA+D G PPLST   I LN
Sbjct: 382 VTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTETIISLN 441

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ++D NDNPP+F   S+ V+V ENN  G  + S+ A DPD   NA +SYSL E   +    
Sbjct: 442 VADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTLQGAPL 501

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SS++S+N  TG ++A RSFDYEQ + LQ  V A D G+PPLSS V++ LFVLD NDNAP 
Sbjct: 502 SSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQNDNAPE 561

Query: 565 VLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSR 623
           +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  
Sbjct: 562 ILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGL 621

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSA 681
           + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     +
Sbjct: 622 HTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPS 681

Query: 682 PREGESRLTLYLAVSLVAICFVSFGSFVALLS 713
            +  +S LTLYL V++ A+  V     + LL+
Sbjct: 682 AKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLA 713


>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  574 bits (1480), Expect = e-163
 Identities = 312/692 (45%), Positives = 432/692 (62%), Gaps = 6/692 (0%)

Query: 25  GYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGAL 84
           G    QIRY +PEE ++G+FVGN+ +D  L+   L+   +++      + F ++  +G+L
Sbjct: 25  GAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNPRNGSL 84

Query: 85  LIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGE 144
           +    IDRE LC  S  C+V    + E  L +Y  EVEIVD+ND+ PRF +++L+++I E
Sbjct: 85  VTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELEVKILE 144

Query: 145 AAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREK 204
            A P  RFPL +  D DVG NS+  ++LS N HF++DV+  + G   PEL+LE  LDRE 
Sbjct: 145 NAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGTLDREG 204

Query: 205 QSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQL 264
           ++ YRLVLTA+DGG+P RS  A++ V+VLDVNDN P F Q  YR+SV E+ P G  ++ +
Sbjct: 205 EAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGTPVLAV 264

Query: 265 NASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARD 324
            A+D D G  G VT+ F   T +++  +F L+  TG+++    LD+E  ++YE  V ARD
Sbjct: 265 TATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYEDSSFYELGVEARD 323

Query: 325 GGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGD 384
           G  P +     + + +LDVNDN P + VTS   T+ ESA PGTV+AL  V D DSG NG 
Sbjct: 324 G--PGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDSGLNGL 381

Query: 385 VSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLN 444
           V+  IP  LPF L+ +  N + LVT   LDRE    Y+I VTA+D G PPLST   I LN
Sbjct: 382 VTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTETIISLN 441

Query: 445 ISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSA 504
           ++D NDNPP+F   S+ V+V ENN  G  + S+ A DPD   NA +SYSL E   +    
Sbjct: 442 VADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTLQGAPL 501

Query: 505 SSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPA 564
           SS++S+N  TG ++A RSFDYEQ + LQ  V A D G+PPLSS V++ LFVLD NDNAP 
Sbjct: 502 SSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQNDNAPE 561

Query: 565 VLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSR 623
           +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  
Sbjct: 562 ILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGL 621

Query: 624 YAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSA 681
           + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     +
Sbjct: 622 HTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPS 681

Query: 682 PREGESRLTLYLAVSLVAICFVSFGSFVALLS 713
            +  +S LTLYL V++ A+  V     + LL+
Sbjct: 682 AKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLA 713


>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  573 bits (1478), Expect = e-163
 Identities = 310/701 (44%), Positives = 439/701 (62%), Gaps = 10/701 (1%)

Query: 24  LGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDL 79
           LG +C    GQIRY V EE  +G+FVGN+A D  L+   L+ R +++      + F ++ 
Sbjct: 20  LGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNP 79

Query: 80  DSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLD 139
            SG+L+    IDRE LC     C+V +  + E  L+++  E+EI D+ND+AP FP ++L+
Sbjct: 80  QSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELE 139

Query: 140 LEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKP 199
           ++IGE   PG RFP++ A D DVG NS+ +Y+LS N++F+L V   S+G+  PEL+LE+ 
Sbjct: 140 IKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERA 199

Query: 200 LDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGM 259
           LDREK+  ++LVL A DGG+P  SG   ++V VLD NDN P F Q  YR+SV E+ P G 
Sbjct: 200 LDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGT 259

Query: 260 VLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFD 319
            L+ +NA+DPD G +  V+ Y     P ++  +F L+  +G++++L  LD+E   +YE  
Sbjct: 260 RLLTVNATDPDEGFNAQVS-YILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIK 318

Query: 320 VRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDS 379
           + A+DG  P +     + V +LDVNDNAP IT+TS   ++PE    G  +ALI V D DS
Sbjct: 319 IEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDS 376

Query: 380 GSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHR 439
           G NG V + +  +LPF L+ +    + LVTA  LDRE  S Y+I + ASD G+PPLST  
Sbjct: 377 GQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTET 436

Query: 440 TIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRN 499
            I L++ D+NDNPP+F   S+  ++PENN  G  + S+ A DPDS  NA I+Y+L E   
Sbjct: 437 HITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTL 496

Query: 500 RDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLN 559
           +    SSF+S+N  TG ++A RSFDYEQ + L+  V A D GNPPLSS V++ LFVLD N
Sbjct: 497 QGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQN 556

Query: 560 DNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSL 618
           DNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P L
Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616

Query: 619 FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLR 677
           F+V  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL 
Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676

Query: 678 E-SSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
               + +  +S LTLYL V++ A+  V     + LL+  LR
Sbjct: 677 SLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLR 717


>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 829

 Score =  573 bits (1478), Expect = e-163
 Identities = 310/701 (44%), Positives = 439/701 (62%), Gaps = 10/701 (1%)

Query: 24  LGYVC----GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDL 79
           LG +C    GQIRY V EE  +G+FVGN+A D  L+   L+ R +++      + F ++ 
Sbjct: 20  LGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNP 79

Query: 80  DSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLD 139
            SG+L+    IDRE LC     C+V +  + E  L+++  E+EI D+ND+AP FP ++L+
Sbjct: 80  QSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELE 139

Query: 140 LEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKP 199
           ++IGE   PG RFP++ A D DVG NS+ +Y+LS N++F+L V   S+G+  PEL+LE+ 
Sbjct: 140 IKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERA 199

Query: 200 LDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGM 259
           LDREK+  ++LVL A DGG+P  SG   ++V VLD NDN P F Q  YR+SV E+ P G 
Sbjct: 200 LDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGT 259

Query: 260 VLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFD 319
            L+ +NA+DPD G +  V+ Y     P ++  +F L+  +G++++L  LD+E   +YE  
Sbjct: 260 RLLTVNATDPDEGFNAQVS-YILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIK 318

Query: 320 VRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDS 379
           + A+DG  P +     + V +LDVNDNAP IT+TS   ++PE    G  +ALI V D DS
Sbjct: 319 IEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDS 376

Query: 380 GSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHR 439
           G NG V + +  +LPF L+ +    + LVTA  LDRE  S Y+I + ASD G+PPLST  
Sbjct: 377 GQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTET 436

Query: 440 TIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRN 499
            I L++ D+NDNPP+F   S+  ++PENN  G  + S+ A DPDS  NA I+Y+L E   
Sbjct: 437 HITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTL 496

Query: 500 RDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLN 559
           +    SSF+S+N  TG ++A RSFDYEQ + L+  V A D GNPPLSS V++ LFVLD N
Sbjct: 497 QGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQN 556

Query: 560 DNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSL 618
           DNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P L
Sbjct: 557 DNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGL 616

Query: 619 FAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLR 677
           F+V  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL 
Sbjct: 617 FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLG 676

Query: 678 E-SSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
               + +  +S LTLYL V++ A+  V     + LL+  LR
Sbjct: 677 SLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLR 717


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  569 bits (1466), Expect = e-162
 Identities = 316/706 (44%), Positives = 441/706 (62%), Gaps = 8/706 (1%)

Query: 17  LLFLFYHLGYVCG--QIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRH 74
           LL LF+ + +  G  QI Y +PEE ++G+FVGN+++D  L    L+ R +++      + 
Sbjct: 19  LLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQL 78

Query: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134
           F ++  SG+L+    IDRE LC  SA C+V    + E  ++++  E+E+ D+ND+AP+F 
Sbjct: 79  FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQ 138

Query: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194
            + LD++I E    G RFPL +A D DVG NS+ SY+LS N+HF+L V+ R++G   PEL
Sbjct: 139 AENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPEL 198

Query: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254
           +LE  LDRE+++ + LVLTA DGG+P RSGT  + V+V D NDNAP F    YR+SV E+
Sbjct: 199 VLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPEN 258

Query: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314
            P G  L+ + A+D D G +G VT+ F    PD     F L+  TG++ +   LD+E   
Sbjct: 259 LPVGTQLLTVTATDRDEGANGEVTYSFR-KLPDTQLLKFQLNKYTGEIKISENLDYEETG 317

Query: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374
           +YE +++A DGG+        + V+  DVNDN+P +T+TS    + E +  GTVVAL++V
Sbjct: 318 FYEIEIQAEDGGAYLATAKVLITVE--DVNDNSPELTITSLFSPVTEDSPLGTVVALLNV 375

Query: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434
            D DS  NG V+  I  +LPF L+ +  + + LV    LDRE  SSY+I VTA+D G+PP
Sbjct: 376 HDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPP 435

Query: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494
           LST     L ++D+NDNPP+F Q S+  ++PENN  G  + S+ A DPDS  NA I YSL
Sbjct: 436 LSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSL 495

Query: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554
            E   + V  SS+IS+N  TG ++A RSFDYEQ   LQ +V A D G+PPLSS V++ LF
Sbjct: 496 AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLF 555

Query: 555 VLDLNDNAPAVLRPR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEA 613
           VLD NDNAP +L P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A
Sbjct: 556 VLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKA 615

Query: 614 PDPSLFAVSRYAGEVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPV 672
            +P LFAV  + GEVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    V
Sbjct: 616 SEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQV 675

Query: 673 VPDLRESSAPREGE-SRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
           + DL    +P   E S LTLYL V++ A+  V     + LL+  LR
Sbjct: 676 LADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLR 721


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  569 bits (1466), Expect = e-162
 Identities = 307/693 (44%), Positives = 433/693 (62%), Gaps = 8/693 (1%)

Query: 29  GQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKN 88
           G I Y VPEE+ +G+FVGN+A+D  L    L+   +++        F ++  SG+L+   
Sbjct: 29  GNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITAR 88

Query: 89  PIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPP 148
            IDRE LC  S  C+V    + E  ++++  EVEI+D+ND+ P+F  ++L+ ++ E   P
Sbjct: 89  RIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTP 148

Query: 149 GQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDY 208
           G R  L   QD DVG NS+ SY+LSSN HF+LDV++ +DG   PE++L+ PLDRE+++ +
Sbjct: 149 GTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVH 208

Query: 209 RLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASD 268
            L+LTA DGG P RSGT  + + V+D NDN PAF Q+ Y I+V E+ P G  L+ +NA+D
Sbjct: 209 HLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATD 268

Query: 269 PDLGPSGNVTFYFSGHTPD-RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGS 327
           PD G +G VT+ F  H  D RV  +F L   TG+++   PLDFE    Y  +V+A+DG  
Sbjct: 269 PDEGANGEVTYSF--HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA- 325

Query: 328 PAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSL 387
             +     + + +LDVNDNAP +T+TS    +PE+  PGT++ALISV D DSG NG  + 
Sbjct: 326 -GLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGDNGYTTC 384

Query: 388 RIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISD 447
            IP +LPF L+    N + LVT   LDRE  S Y+I +TA D G P LST   I L ++D
Sbjct: 385 FIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTD 444

Query: 448 VNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSF 507
           +NDN P F Q S+  ++PENN  G  + S+ A D DS  NA I+YSL+E   +    S++
Sbjct: 445 INDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504

Query: 508 ISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLR 567
           +S+N  TG ++A RSFDYEQ + +Q +V ARD G+PPLSS V++ LF+LD NDNAP +L 
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY 564

Query: 568 PR-ARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAG 626
           P     GS   +  P S   G+L+TKV AVD DSG NAW+SY+LL+A +P LF+V  + G
Sbjct: 565 PALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG 624

Query: 627 EVRTA-VPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRE-SSAPRE 684
           EVRTA   +  D   Q LV+ V+D G PPLS +VTL V++ +    ++ DL     + + 
Sbjct: 625 EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILADLGSLEPSAKP 684

Query: 685 GESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717
            +S LTLYL V+  A+  V     + LL+  LR
Sbjct: 685 NDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLR 717


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,991,261
Number of Sequences: 37866
Number of extensions: 1731482
Number of successful extensions: 11265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 4065
Number of HSP's gapped (non-prelim): 687
length of query: 871
length of database: 18,247,518
effective HSP length: 111
effective length of query: 760
effective length of database: 14,044,392
effective search space: 10673737920
effective search space used: 10673737920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.