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Search of human proteins with 14269586
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14269586 mitochondrial ribosomal protein S26 [Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14269586 mitochondrial ribosomal protein S26 [Homo sapiens] 404 e-113
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 51 8e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 46 3e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 46 3e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 46 3e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 46 3e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 46 3e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 46 3e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 46 3e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 46 3e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 46 3e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 46 3e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 46 3e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 46 3e-05
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 46 3e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 45 4e-05
gi|154354979 myosin X [Homo sapiens] 44 7e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 43 2e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 43 2e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 43 2e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 43 2e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 43 2e-04
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 43 2e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 43 2e-04
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 43 2e-04
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 43 2e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 43 2e-04
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 43 2e-04
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l... 42 3e-04
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 42 3e-04
>gi|14269586 mitochondrial ribosomal protein S26 [Homo sapiens]
Length = 205
Score = 404 bits (1037), Expect = e-113
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MLRALSRLGAGTPCRPRAPLVLPARGRKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERY 60
MLRALSRLGAGTPCRPRAPLVLPARGRKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERY
Sbjct: 1 MLRALSRLGAGTPCRPRAPLVLPARGRKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERY 60
Query: 61 QHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELR 120
QHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELR
Sbjct: 61 QHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELR 120
Query: 121 IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA
Sbjct: 121 IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
Query: 181 LDSRKNYNWAITREGLVVRPQRRDS 205
LDSRKNYNWAITREGLVVRPQRRDS
Sbjct: 181 LDSRKNYNWAITREGLVVRPQRRDS 205
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 50.8 bits (120), Expect = 8e-07
Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 78 VQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQA- 136
+Q K + + V A K EH+ ++A Q R L +++E+ E EQR+A
Sbjct: 543 LQEKEEQHQLAVTAYLK--NSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
Query: 137 LEQARKAEEVQAWAQRKERE---VLQLQEEVKNFITRENLE 174
L++ RKAEE + + KERE +LQ E++K RE LE
Sbjct: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLE 641
Score = 38.9 bits (89), Expect = 0.003
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 17/152 (11%)
Query: 44 MPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHR 103
M ++ + FV+ R + RQ+V E + + + ++ E R L ERK + E R
Sbjct: 750 MSRMLEDRDLFVM--RLKAARQSVYE---EKLKQFEERLAEERHNRLEERK--RQRKEER 802
Query: 104 ELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQR------KEREV 157
+ + + E E R A Q +E+E+R+ E+A++ EE++ + +R ER+
Sbjct: 803 RITYYREKEE---EEQRRAE-EQMLKEREERERAERAKREEELREYQERVKKLEEVERKK 858
Query: 158 LQLQEEVKNFITRENLEARVEAALDSRKNYNW 189
Q + E++ R E R+ + SRK+ W
Sbjct: 859 RQRELEIEERERRREEERRLGDSSLSRKDSRW 890
Score = 33.1 bits (74), Expect = 0.17
Identities = 28/123 (22%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 55 VLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAE---HRELMAWNQA 111
+L E+ + ++ V A E QR + AR + ERK ++ +E + +A
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRIL--ARRQTIEERKERLESLNIQREKEELEQREA 599
Query: 112 ENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRE 171
E +++ + RLRQE +E+E+ + L++ + ++ + ++ + +L + I E
Sbjct: 600 ELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIE 659
Query: 172 NLE 174
+LE
Sbjct: 660 DLE 662
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 5/142 (3%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
RQ LR + E +R+ E A E + + L + E R+ E + R
Sbjct: 757 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 816
Query: 124 LRQEEREQEQRQALEQ--ARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAAL 181
L + RE+E+R+ E+ ++ EE WA+ +E +L+E N + E AR+
Sbjct: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE---NRLRMEEEAARLRHEE 873
Query: 182 DSRKNYNWAITREGLVVRPQRR 203
+ RK + R+ ++R +++
Sbjct: 874 EERKRKELEVQRQKELMRQRQQ 895
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Query: 67 VRALRMEFVSEVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAE---NRRLHELRIA 122
+RA R E + Q ++ + +L +++ + E EL Q E +R E+ +
Sbjct: 740 MRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 799
Query: 123 RLRQEEREQEQRQA---LEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEAR 176
R R+EE Q+Q +A LE+ R+ EE +RK+ E+L+ QEE RE EA+
Sbjct: 800 RQREEEERQQQEEALRRLEERRREEE----ERRKQEELLRKQEEEAAKWAREEEEAQ 852
Score = 36.2 bits (82), Expect = 0.020
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 95 ALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ---------RQALEQARKAEE 145
AL+ + + A + RR E+R R +E + QE+ R+ E+ RK E
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 146 VQAWAQRKEREVLQLQEEVKNFITRENLE 174
+ A+RK+ E L+ Q E + + R+ E
Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREE 804
Score = 35.0 bits (79), Expect = 0.045
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 77 EVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQ 135
E +++ +A+A L ER+ + A+ E Q E RR E + R ++EER++ + +
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 136 ALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVE 178
E AR+ +E QR++ L+ Q E + +E R+E
Sbjct: 778 --ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 818
Score = 33.5 bits (75), Expect = 0.13
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Q + +R L E +R+ E E +A K A E E ENR
Sbjct: 805 EERQQQEEALRRLEERRREEEERRKQEELLRK-QEEEAAKWAREEEEAQR-RLEENRLRM 862
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEE 163
E ARLR EE E+++++ + ++ +E+ Q+++ + +LQ++
Sbjct: 863 EEEAARLRHEEEERKRKEL--EVQRQKELMRQRQQQQEALRRLQQQ 906
Score = 31.6 bits (70), Expect = 0.49
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 77 EVQRKVHEARAGVLAERKALKDAAEHR---ELMAWNQAENRRLHELRIARLRQEEREQEQ 133
E QR++ E R + E L+ E R EL Q E R + + LR+ +++Q+Q
Sbjct: 850 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 909
Query: 134 RQALEQARKAEEVQAWAQRKEREVLQLQ 161
+Q + K W Q+ Q Q
Sbjct: 910 QQLAQM--KLPSSSTWGQQSNTTACQSQ 935
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 114 RRLHELRIARLRQE--------EREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVK 165
++L + + A+L QE +RE+E+R+ E+ R+ +E Q++E + +EE+
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
Query: 166 NFITRENLEARVEAALDSRK 185
E L + E + R+
Sbjct: 781 RRKQEEALRRQREQEIALRR 800
Score = 27.3 bits (59), Expect = 9.3
Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 9/62 (14%)
Query: 111 AENRRLHELRIARLRQEEREQEQR--QALEQARKAEE--VQAWAQRKE-----REVLQLQ 161
AE ++L E R +LR+E+R Q++ +AL+Q ++ ++ + W + + +L++Q
Sbjct: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1000
Query: 162 EE 163
+E
Sbjct: 1001 QE 1002
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 5/142 (3%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
RQ LR + E +R+ E A E + + L + E R+ E + R
Sbjct: 784 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 843
Query: 124 LRQEEREQEQRQALEQ--ARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAAL 181
L + RE+E+R+ E+ ++ EE WA+ +E +L+E N + E AR+
Sbjct: 844 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE---NRLRMEEEAARLRHEE 900
Query: 182 DSRKNYNWAITREGLVVRPQRR 203
+ RK + R+ ++R +++
Sbjct: 901 EERKRKELEVQRQKELMRQRQQ 922
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Query: 67 VRALRMEFVSEVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAE---NRRLHELRIA 122
+RA R E + Q ++ + +L +++ + E EL Q E +R E+ +
Sbjct: 767 MRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 826
Query: 123 RLRQEEREQEQRQA---LEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEAR 176
R R+EE Q+Q +A LE+ R+ EE +RK+ E+L+ QEE RE EA+
Sbjct: 827 RQREEEERQQQEEALRRLEERRREEE----ERRKQEELLRKQEEEAAKWAREEEEAQ 879
Score = 36.2 bits (82), Expect = 0.020
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 95 ALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ---------RQALEQARKAEE 145
AL+ + + A + RR E+R R +E + QE+ R+ E+ RK E
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 146 VQAWAQRKEREVLQLQEEVKNFITRENLE 174
+ A+RK+ E L+ Q E + + R+ E
Sbjct: 803 EEELARRKQEEALRRQREQEIALRRQREE 831
Score = 35.0 bits (79), Expect = 0.045
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 77 EVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQ 135
E +++ +A+A L ER+ + A+ E Q E RR E + R ++EER++ + +
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
Query: 136 ALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVE 178
E AR+ +E QR++ L+ Q E + +E R+E
Sbjct: 805 --ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 845
Score = 33.5 bits (75), Expect = 0.13
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Q + +R L E +R+ E E +A K A E E ENR
Sbjct: 832 EERQQQEEALRRLEERRREEEERRKQEELLRK-QEEEAAKWAREEEEAQR-RLEENRLRM 889
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEE 163
E ARLR EE E+++++ + ++ +E+ Q+++ + +LQ++
Sbjct: 890 EEEAARLRHEEEERKRKEL--EVQRQKELMRQRQQQQEALRRLQQQ 933
Score = 31.6 bits (70), Expect = 0.49
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 77 EVQRKVHEARAGVLAERKALKDAAEHR---ELMAWNQAENRRLHELRIARLRQEEREQEQ 133
E QR++ E R + E L+ E R EL Q E R + + LR+ +++Q+Q
Sbjct: 877 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 936
Query: 134 RQALEQARKAEEVQAWAQRKEREVLQLQ 161
+Q + K W Q+ Q Q
Sbjct: 937 QQLAQM--KLPSSSTWGQQSNTTACQSQ 962
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 114 RRLHELRIARLRQE--------EREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVK 165
++L + + A+L QE +RE+E+R+ E+ R+ +E Q++E + +EE+
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
Query: 166 NFITRENLEARVEAALDSRK 185
E L + E + R+
Sbjct: 808 RRKQEEALRRQREQEIALRR 827
Score = 27.3 bits (59), Expect = 9.3
Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 9/62 (14%)
Query: 111 AENRRLHELRIARLRQEEREQEQR--QALEQARKAEE--VQAWAQRKE-----REVLQLQ 161
AE ++L E R +LR+E+R Q++ +AL+Q ++ ++ + W + + +L++Q
Sbjct: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1027
Query: 162 EE 163
+E
Sbjct: 1028 QE 1029
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 5/142 (3%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
RQ LR + E +R+ E A E + + L + E R+ E + R
Sbjct: 763 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 822
Query: 124 LRQEEREQEQRQALEQ--ARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAAL 181
L + RE+E+R+ E+ ++ EE WA+ +E +L+E N + E AR+
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE---NRLRMEEEAARLRHEE 879
Query: 182 DSRKNYNWAITREGLVVRPQRR 203
+ RK + R+ ++R +++
Sbjct: 880 EERKRKELEVQRQKELMRQRQQ 901
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Query: 67 VRALRMEFVSEVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAE---NRRLHELRIA 122
+RA R E + Q ++ + +L +++ + E EL Q E +R E+ +
Sbjct: 746 MRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 805
Query: 123 RLRQEEREQEQRQA---LEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEAR 176
R R+EE Q+Q +A LE+ R+ EE +RK+ E+L+ QEE RE EA+
Sbjct: 806 RQREEEERQQQEEALRRLEERRREEE----ERRKQEELLRKQEEEAAKWAREEEEAQ 858
Score = 36.2 bits (82), Expect = 0.020
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 95 ALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ---------RQALEQARKAEE 145
AL+ + + A + RR E+R R +E + QE+ R+ E+ RK E
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 146 VQAWAQRKEREVLQLQEEVKNFITRENLE 174
+ A+RK+ E L+ Q E + + R+ E
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREE 810
Score = 35.0 bits (79), Expect = 0.045
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 77 EVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQ 135
E +++ +A+A L ER+ + A+ E Q E RR E + R ++EER++ + +
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 136 ALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVE 178
E AR+ +E QR++ L+ Q E + +E R+E
Sbjct: 784 --ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 824
Score = 33.5 bits (75), Expect = 0.13
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Q + +R L E +R+ E E +A K A E E ENR
Sbjct: 811 EERQQQEEALRRLEERRREEEERRKQEELLRK-QEEEAAKWAREEEEAQR-RLEENRLRM 868
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEE 163
E ARLR EE E+++++ + ++ +E+ Q+++ + +LQ++
Sbjct: 869 EEEAARLRHEEEERKRKEL--EVQRQKELMRQRQQQQEALRRLQQQ 912
Score = 31.6 bits (70), Expect = 0.49
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 77 EVQRKVHEARAGVLAERKALKDAAEHR---ELMAWNQAENRRLHELRIARLRQEEREQEQ 133
E QR++ E R + E L+ E R EL Q E R + + LR+ +++Q+Q
Sbjct: 856 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 915
Query: 134 RQALEQARKAEEVQAWAQRKEREVLQLQ 161
+Q + K W Q+ Q Q
Sbjct: 916 QQLAQM--KLPSSSTWGQQSNTTACQSQ 941
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 114 RRLHELRIARLRQE--------EREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVK 165
++L + + A+L QE +RE+E+R+ E+ R+ +E Q++E + +EE+
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 166 NFITRENLEARVEAALDSRK 185
E L + E + R+
Sbjct: 787 RRKQEEALRRQREQEIALRR 806
Score = 27.3 bits (59), Expect = 9.3
Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 9/62 (14%)
Query: 111 AENRRLHELRIARLRQEEREQEQR--QALEQARKAEE--VQAWAQRKE-----REVLQLQ 161
AE ++L E R +LR+E+R Q++ +AL+Q ++ ++ + W + + +L++Q
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
Query: 162 EE 163
+E
Sbjct: 1007 QE 1008
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 3e-05
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 5/142 (3%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
RQ LR + E +R+ E A E + + L + E R+ E + R
Sbjct: 763 RQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRR 822
Query: 124 LRQEEREQEQRQALEQ--ARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAAL 181
L + RE+E+R+ E+ ++ EE WA+ +E +L+E N + E AR+
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE---NRLRMEEEAARLRHEE 879
Query: 182 DSRKNYNWAITREGLVVRPQRR 203
+ RK + R+ ++R +++
Sbjct: 880 EERKRKELEVQRQKELMRQRQQ 901
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Query: 67 VRALRMEFVSEVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAE---NRRLHELRIA 122
+RA R E + Q ++ + +L +++ + E EL Q E +R E+ +
Sbjct: 746 MRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALR 805
Query: 123 RLRQEEREQEQRQA---LEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEAR 176
R R+EE Q+Q +A LE+ R+ EE +RK+ E+L+ QEE RE EA+
Sbjct: 806 RQREEEERQQQEEALRRLEERRREEE----ERRKQEELLRKQEEEAAKWAREEEEAQ 858
Score = 36.2 bits (82), Expect = 0.020
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 9/89 (10%)
Query: 95 ALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ---------RQALEQARKAEE 145
AL+ + + A + RR E+R R +E + QE+ R+ E+ RK E
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 146 VQAWAQRKEREVLQLQEEVKNFITRENLE 174
+ A+RK+ E L+ Q E + + R+ E
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREE 810
Score = 35.0 bits (79), Expect = 0.045
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 77 EVQRKVHEARAGVLA-ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQ 135
E +++ +A+A L ER+ + A+ E Q E RR E + R ++EER++ + +
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 136 ALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVE 178
E AR+ +E QR++ L+ Q E + +E R+E
Sbjct: 784 --ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLE 824
Score = 33.5 bits (75), Expect = 0.13
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Q + +R L E +R+ E E +A K A E E ENR
Sbjct: 811 EERQQQEEALRRLEERRREEEERRKQEELLRK-QEEEAAKWAREEEEAQR-RLEENRLRM 868
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEE 163
E ARLR EE E+++++ + ++ +E+ Q+++ + +LQ++
Sbjct: 869 EEEAARLRHEEEERKRKEL--EVQRQKELMRQRQQQQEALRRLQQQ 912
Score = 31.6 bits (70), Expect = 0.49
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 77 EVQRKVHEARAGVLAERKALKDAAEHR---ELMAWNQAENRRLHELRIARLRQEEREQEQ 133
E QR++ E R + E L+ E R EL Q E R + + LR+ +++Q+Q
Sbjct: 856 EAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 915
Query: 134 RQALEQARKAEEVQAWAQRKEREVLQLQ 161
+Q + K W Q+ Q Q
Sbjct: 916 QQLAQM--KLPSSSTWGQQSNTTACQSQ 941
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 114 RRLHELRIARLRQE--------EREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVK 165
++L + + A+L QE +RE+E+R+ E+ R+ +E Q++E + +EE+
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 166 NFITRENLEARVEAALDSRK 185
E L + E + R+
Sbjct: 787 RRKQEEALRRQREQEIALRR 806
Score = 27.3 bits (59), Expect = 9.3
Identities = 17/62 (27%), Positives = 37/62 (59%), Gaps = 9/62 (14%)
Query: 111 AENRRLHELRIARLRQEEREQEQR--QALEQARKAEE--VQAWAQRKE-----REVLQLQ 161
AE ++L E R +LR+E+R Q++ +AL+Q ++ ++ + W + + +L++Q
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQ 1006
Query: 162 EE 163
+E
Sbjct: 1007 QE 1008
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1419 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1475
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1522
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1346
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1347 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1404 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1435
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1460
Query: 173 LEA 175
LEA
Sbjct: 1461 LEA 1463
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1500
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1555
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 2004 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2118
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2119 QSAEEQAQARAQAQAAAEK 2137
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1660 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1719
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1720 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1773
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2558
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2615
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2049 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2107
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2160
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2188
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2325 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2377
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2000
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1845 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1902
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1903 DSELERQKGLVEDTLRQRRQVEE 1925
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2509
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2555
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1423 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1479
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1480 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1526
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1294 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1350
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1351 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1407
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1408 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1439
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1348 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1407
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1464
Query: 173 LEA 175
LEA
Sbjct: 1465 LEA 1467
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2509 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2567
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2568 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2607
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1452 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1504
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1505 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1559
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 2008 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2062
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2063 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2122
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2123 QSAEEQAQARAQAQAAAEK 2141
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1664 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1723
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1724 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1777
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2506 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2562
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2563 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2619
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2053 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2111
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2164
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2192
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2269 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2328
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2329 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2381
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1945 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2004
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 2005 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2045
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1849 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1906
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1907 DSELERQKGLVEDTLRQRRQVEE 1929
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2454 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2513
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2514 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2559
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1419 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1475
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1522
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1346
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1347 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1404 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1435
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1460
Query: 173 LEA 175
LEA
Sbjct: 1461 LEA 1463
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1500
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1555
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 2004 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2118
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2119 QSAEEQAQARAQAQAAAEK 2137
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1660 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1719
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1720 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1773
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2558
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2615
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2049 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2107
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2160
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2188
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2325 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2377
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2000
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1845 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1902
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1903 DSELERQKGLVEDTLRQRRQVEE 1925
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2509
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2555
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1387 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1443
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1444 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1490
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1258 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1314
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1315 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1371
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1372 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1403
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1312 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1371
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1428
Query: 173 LEA 175
LEA
Sbjct: 1429 LEA 1431
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2473 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2531
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2532 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2571
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1416 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1468
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1469 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1523
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 1972 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2026
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2027 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2086
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2087 QSAEEQAQARAQAQAAAEK 2105
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1628 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1687
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1688 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1741
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2470 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2526
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2527 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2583
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2017 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2075
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2128
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2156
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2233 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2292
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2293 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2345
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1909 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 1968
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 1969 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2009
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1813 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1870
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1871 DSELERQKGLVEDTLRQRRQVEE 1893
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2418 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2477
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2478 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2523
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1556 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1612
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1613 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1659
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1427 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1483
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1484 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1540
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1541 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1572
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1540
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1597
Query: 173 LEA 175
LEA
Sbjct: 1598 LEA 1600
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2642 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2700
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2701 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2740
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1585 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1637
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1638 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1692
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 2141 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2195
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2196 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2255
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2256 QSAEEQAQARAQAQAAAEK 2274
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1797 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1856
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1857 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1910
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2639 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2695
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2752
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2186 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2244
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2245 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2297
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2325
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2402 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2461
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2462 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2514
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 2078 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2137
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 2138 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2178
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1982 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 2039
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 2040 DSELERQKGLVEDTLRQRRQVEE 2062
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2587 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2646
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2647 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2692
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1397 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1453
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1454 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1500
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1268 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1324
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1325 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1381
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1382 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1413
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1322 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1381
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1438
Query: 173 LEA 175
LEA
Sbjct: 1439 LEA 1441
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2483 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2541
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2542 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2581
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1426 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1478
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1479 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1533
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 1982 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2036
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2037 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2096
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2097 QSAEEQAQARAQAQAAAEK 2115
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1638 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1697
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1698 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1751
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2480 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2536
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2537 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2593
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2027 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2085
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2086 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2138
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2166
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2243 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2302
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2303 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2355
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1919 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 1978
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 1979 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2019
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1823 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1880
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1881 DSELERQKGLVEDTLRQRRQVEE 1903
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2428 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2487
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2488 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2533
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1405 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1461
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1462 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1508
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1276 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1332
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1333 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1389
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1390 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1421
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1330 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1389
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1446
Query: 173 LEA 175
LEA
Sbjct: 1447 LEA 1449
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2491 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2549
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2550 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2589
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1434 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1486
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1487 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1541
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 1990 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2044
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2045 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2104
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2105 QSAEEQAQARAQAQAAAEK 2123
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1646 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1705
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1706 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1759
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2488 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2544
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2545 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2601
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2035 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2093
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2094 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2146
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2174
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2251 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2310
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2311 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2363
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1927 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 1986
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 1987 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2027
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1831 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1888
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1889 DSELERQKGLVEDTLRQRRQVEE 1911
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2436 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2495
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2496 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2541
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH----EL 119
++ ++ LR +E+Q K +A A AER L+ E R + +A R+ EL
Sbjct: 1446 QEELQQLRQSSEAEIQAKARQAEA---AERSRLRIEEEIRVVRLQLEATERQRGGAEGEL 1502
Query: 120 RIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVK 165
+ R R EE E ++RQA E+A R +VQ +QRK + ++L VK
Sbjct: 1503 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVK 1549
Score = 43.5 bits (101), Expect = 1e-04
Identities = 46/157 (29%), Positives = 78/157 (49%), Gaps = 24/157 (15%)
Query: 36 KSKIERVNMP---PAVDPAEFFVLMERYQ---HYRQ--TVRALRMEFVSEVQRKVHEARA 87
K+++E V P P V V+ E HY + T+ + ++F+SE R++ E
Sbjct: 1317 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEE--- 1373
Query: 88 GVLAERKALKDAAEHRELMAWNQA---ENRRLHELRIARLRQEEREQE--QRQALEQARK 142
ER A + AE RE +A +A + R+L E Q ERE + Q++ E+ +
Sbjct: 1374 ---EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1430
Query: 143 AEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
EE AQ+++R + QEE++ R++ EA ++A
Sbjct: 1431 REEAAVDAQQQKRSI---QEELQQL--RQSSEAEIQA 1462
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 57 MERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAA-EHRELMAWNQAENRR 115
ME + + RA E ++EV+ + + R A +A A E +EL Q E R
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1430
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQA---WAQRKEREVLQLQEEVKNFITREN 172
E + +Q+ QE+ Q L Q+ +A E+QA A+ ER L+++EE++ + R
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEA-EIQAKARQAEAAERSRLRIEEEIR--VVRLQ 1487
Query: 173 LEA 175
LEA
Sbjct: 1488 LEA 1490
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE-- 128
R F+ + + K+ + +A+ + L++ + R+ Q R + + AR RQ E
Sbjct: 2532 RERFIEQEKAKLEQLFQDEVAKAQQLREE-QQRQQQQMEQERQRLVASMEEARRRQHEAE 2590
Query: 129 ----REQEQRQALEQARKA-EEVQAWAQRKEREVLQLQEE 163
R+QE+ Q LEQ R+ EE+ A ++ RE LQL EE
Sbjct: 2591 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2630
Score = 35.4 bits (80), Expect = 0.034
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 70 LRMEFVSEVQRKVHEA----RAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLR 125
LR+E V R EA R G E +AL+ AE E A+ R+ E RLR
Sbjct: 1475 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE------AQKRQAQE-EAERLR 1527
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQ--RKEREVLQLQEEVKNFITRENLEARVEAA 180
++ +++ QR+ + A V+A A+ R+++ LQ EE++ + E E R+ A
Sbjct: 1528 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR--LQAEEAERRLRQA 1582
Score = 34.7 bits (78), Expect = 0.058
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 26/139 (18%)
Query: 68 RALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH-ELRIARLRQ 126
R +E V ++ KV EAR L ER + A R+L +A +RL E +
Sbjct: 2031 RKAALEEVERLKAKVEEARR--LRERAEQESA---RQLQLAQEAAQKRLQAEEKAHAFAV 2085
Query: 127 EEREQEQRQALEQ---------------ARKAEEVQAWAQRKEREVLQLQEEVKNF---- 167
+++EQE +Q L+Q R AEE + + ERE Q + +V+
Sbjct: 2086 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLK 2145
Query: 168 -ITRENLEARVEAALDSRK 185
E +AR +A + K
Sbjct: 2146 QSAEEQAQARAQAQAAAEK 2164
Score = 33.1 bits (74), Expect = 0.17
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 76 SEVQRKVHEARAGVLAERKALKDAAEHREL----------MAWNQAENRRLHELRIARLR 125
+E +++ EA KA + A REL +A A+ R E + RLR
Sbjct: 1687 AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1746
Query: 126 QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSR 184
E + EQ++ L EE A QR+ Q ++E++ + + E V A +R
Sbjct: 1747 AETEQGEQQRQL-----LEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAR 1800
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 13/118 (11%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L++R + Q L F EV K + R +++ ++ E + L+A + RR
Sbjct: 2529 LLQRERFIEQEKAKLEQLFQDEVA-KAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRR 2585
Query: 116 LHELR---------IARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEV 164
HE + +L Q+ R+QE+ A E R E++Q + + R L EEV
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL-LEEQHRAALAHSEEV 2642
Score = 32.0 bits (71), Expect = 0.38
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 21/148 (14%)
Query: 47 AVDPAEFFVLMERYQHYRQTVRA-------LRMEFVSEVQRKVHEAR-AGVLAERKALK- 97
A + A F + ++ Q +QT++ LR E +R EA A V AER+A +
Sbjct: 2076 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE-AEAARRAAEEAEEARVQAEREAAQS 2134
Query: 98 ----DAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
+ AE + A QA+ R + +LR+E + E AR+A+ QA ++K
Sbjct: 2135 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ-------EAARRAQAEQAALRQK 2187
Query: 154 EREVLQLQEEVKNFITRENLEARVEAAL 181
+ ++++ K +A+VE L
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQEL 2215
Score = 30.8 bits (68), Expect = 0.84
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Query: 74 FVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQ 133
F+ E K+ + A ++AA R+L + A+ R L E + Q +E +
Sbjct: 2292 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2351
Query: 134 RQA----LEQARKAEEVQAWAQRKEREVL--QLQEEVKNFITRENLEARVEAALD 182
+A L+Q ++ + QA ++++E + QL EE + F + LEA + L+
Sbjct: 2352 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF--QRTLEAERQRQLE 2404
Score = 30.4 bits (67), Expect = 1.1
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 71 RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHE-LRIARLRQEER 129
+ E E+ R A + ++ +A +AA R+L A + R E ++ + +EE
Sbjct: 1968 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2027
Query: 130 EQEQRQALEQAR----KAEEVQAWAQRKERE---VLQLQEE 163
++++ ALE+ K EE + +R E+E LQL +E
Sbjct: 2028 ARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2068
Score = 27.7 bits (60), Expect = 7.1
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 69 ALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEE 128
A R++ +E+ K EA L R+ +D A R + A+++ E R+A+LR+
Sbjct: 1872 ATRLKTEAEIALKEKEAENERL--RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1929
Query: 129 REQEQRQ------ALEQARKAEE 145
+ +RQ L Q R+ EE
Sbjct: 1930 DSELERQKGLVEDTLRQRRQVEE 1952
Score = 27.3 bits (59), Expect = 9.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 73 EFVSEVQRKVHEAR--AGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEERE 130
E ++E++R+ + + A +L + + +L+ QA + + + L++E
Sbjct: 2477 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2536
Query: 131 QEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAA 180
++++ LEQ + E +A R+E++ Q Q E + R+ L A +E A
Sbjct: 2537 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE----RQRLVASMEEA 2582
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
[Homo sapiens]
Length = 568
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/101 (35%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 78 VQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQAL 137
+++ E +A AE+KA K A+ +E A E +R EL ARL +E+ E+E RQ
Sbjct: 280 IKKFKEEEKAKKEAEKKA-KAEAKRKEQEA---KEKQRQAELEAARLAKEKEEEEVRQQA 335
Query: 138 EQARKAEEVQAWAQRKEREVLQLQ---EEVKNFITRENLEA 175
A+K +++Q A +KER+ L+ EE+ I +E EA
Sbjct: 336 LLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEA 376
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.1 bits (105), Expect = 4e-05
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 16/134 (11%)
Query: 58 ERYQHYRQTVRALRMEFV-SEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRL 116
ER + R + A E + +E +K+ + RA + AE KA AA+ RE + E R
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA---AAQERERREAEERERMRE 319
Query: 117 HELRIARLRQEEREQEQRQALEQAR-KAEEVQAWAQRK-----------EREVLQLQEEV 164
E R A RQ +E+E+R A E+ R K EE +A +R+ ER+ + +EE
Sbjct: 320 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379
Query: 165 KNFITRENLEARVE 178
K + + ++E
Sbjct: 380 KAKVEEQKRNKQLE 393
Score = 36.2 bits (82), Expect = 0.020
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 8/79 (10%)
Query: 92 ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEER-----EQEQRQALEQARKAEEV 146
ER+ D H E M + E++ E ARL EER EQ+++ A E+AR E
Sbjct: 243 EREQGSDEISHHEKM---EEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE 299
Query: 147 QAWAQRKEREVLQLQEEVK 165
+A AQ +ER + +E ++
Sbjct: 300 KAAAQERERREAEERERMR 318
Score = 30.8 bits (68), Expect = 0.84
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 65 QTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARL 124
+ +R R E SE K+ + + E + LK E R + + E RR E +L
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL-EEEEQRRKQEEADRKL 595
Query: 125 RQEEREQEQRQALEQARKAEEVQ 147
R+EE ++ ++ +E+ R+AE +
Sbjct: 596 REEEEKRRLKEEIER-RRAEAAE 617
Score = 30.0 bits (66), Expect = 1.4
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
Query: 98 DAAEHRELMAWNQAENRRLHELRIARLRQEE------REQEQRQALEQARKAEEVQAWAQ 151
D E R + + E RL RIA R ++ RE+ +R E+ R+ +E ++ Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 152 RKEREVLQLQ-----EEVKNFITRENLEARVEAALDSR 184
++ + Q EE K T +E EAA R
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLER 99
Score = 30.0 bits (66), Expect = 1.4
Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 125 RQEEREQ-------EQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARV 177
++EEREQ ++ E +AE +A + +ERE ++ +++ K R +EA
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE 299
Query: 178 EAALDSRK 185
+AA R+
Sbjct: 300 KAAAQERE 307
Score = 29.6 bits (65), Expect = 1.9
Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 10/96 (10%)
Query: 90 LAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAW 149
L E + + E E Q + EL + ++EER + + EQ RK EE
Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE-EQRRKQEE---- 590
Query: 150 AQRKEREVLQLQEEVKNFITRENLEARVEAALDSRK 185
A RK RE EE K + E R EAA +K
Sbjct: 591 ADRKLRE-----EEEKRRLKEEIERRRAEAAEKRQK 621
Score = 28.9 bits (63), Expect = 3.2
Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVH---EARAGVLAERKALKDAAEHRELMAWNQAENR 114
+R RQ RA E ++K + E + + E K + E + W +
Sbjct: 364 KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA 423
Query: 115 RLHELRIARLRQEERE-----QEQRQALEQAR---KAEEVQAWAQRKEREVLQLQEEVKN 166
+ +L+ A L+++ E Q +R+ L++ + K EE++ +K++E +EEVK+
Sbjct: 424 QEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP---KEEVKS 480
Query: 167 FITRE 171
F+ R+
Sbjct: 481 FMDRK 485
Score = 28.9 bits (63), Expect = 3.2
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 15/87 (17%)
Query: 114 RRLHELR----------IARLRQEERE-----QEQRQALEQARKAEEVQAWAQRKEREVL 158
+RL ELR +L+Q+++E +E ++ E+ RK E + +++E
Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR 593
Query: 159 QLQEEVKNFITRENLEARVEAALDSRK 185
+L+EE + +E +E R A + R+
Sbjct: 594 KLREEEEKRRLKEEIERRRAEAAEKRQ 620
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 44.3 bits (103), Expect = 7e-05
Identities = 38/157 (24%), Positives = 75/157 (47%), Gaps = 17/157 (10%)
Query: 54 FVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKAL--KDAAEHRELMAWNQA 111
F+L R+ H ++ + + ++ R+V+ +LAE++ K E E +
Sbjct: 779 FLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQ---LLAEKREQEEKKKQEEEEKKKREEE 835
Query: 112 ENRRLHELRIARLR----QEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNF 167
E R E R A LR +E R+Q++ +AL++++K E+ + K++E Q++E ++
Sbjct: 836 ERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE-KQKENKQVEEILR-- 892
Query: 168 ITRENLEARVEAALDSRKNYNWAITREGLVVRPQRRD 204
LE +E ++ ++T L +RRD
Sbjct: 893 -----LEKEIEDLQRMKEQQELSLTEASLQKLQERRD 924
Score = 27.3 bits (59), Expect = 9.3
Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Query: 51 AEFFVLMERYQHYRQTVRAL-RMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWN 109
AE E +Q + AL + + +E+ R++ + + E + L+ E +L
Sbjct: 846 AELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVE-EILRLEKEIEDLQRMK 904
Query: 110 QAENRRLHELRIARLRQEEREQEQRQALEQA-RKAEEVQAWAQRKEREVLQLQEEVKNFI 168
+ + L E + +L QE R+QE R+ E+A R A+E E + E +
Sbjct: 905 EQQELSLTEASLQKL-QERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
Query: 169 TRENLEARVEAALDSRKNYNWA 190
E E+A + + N+N++
Sbjct: 964 GSEFSSELAESACEEKPNFNFS 985
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 15/133 (11%)
Query: 42 VNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQ--RKVHEARAGVLAER-KALKD 98
VN+P F+ ++ Q ++ ALR + + + Q R+ E + +LAER K ++
Sbjct: 344 VNVPGESTLRRDFLRLQ--QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQ 401
Query: 99 AAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVL 158
E R + + + RR E R RQ+EREQ +R+ E+ R+ EE++ +RKE E
Sbjct: 402 QKEQRRRL---EEQQRREREAR----RQQEREQRRREQ-EEKRRLEELER--RRKEEEER 451
Query: 159 QLQEEVKNFITRE 171
+ EE K + RE
Sbjct: 452 RRAEEEKRRVERE 464
Score = 42.4 bits (98), Expect = 3e-04
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 15/109 (13%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Y+ R R+E E +R++ E + ER+A + + RE Q E RRL
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQR---REREARRQ--QEREQRRREQEEKRRLE 439
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKN 166
EL R+ + E+E+R+A E+ R+ E Q + +R QL+EE ++
Sbjct: 440 ELE----RRRKEEEERRRAEEEKRRVEREQEYIRR------QLEEEQRH 478
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 15/133 (11%)
Query: 42 VNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQ--RKVHEARAGVLAER-KALKD 98
VN+P F+ ++ Q ++ ALR + + + Q R+ E + +LAER K ++
Sbjct: 344 VNVPGESTLRRDFLRLQ--QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQ 401
Query: 99 AAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVL 158
E R + + + RR E R RQ+EREQ +R+ E+ R+ EE++ +RKE E
Sbjct: 402 QKEQRRRL---EEQQRREREAR----RQQEREQRRREQ-EEKRRLEELER--RRKEEEER 451
Query: 159 QLQEEVKNFITRE 171
+ EE K + RE
Sbjct: 452 RRAEEEKRRVERE 464
Score = 42.4 bits (98), Expect = 3e-04
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 15/109 (13%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Y+ R R+E E +R++ E + ER+A + + RE Q E RRL
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQR---REREARRQ--QEREQRRREQEEKRRLE 439
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKN 166
EL R+ + E+E+R+A E+ R+ E Q + +R QL+EE ++
Sbjct: 440 ELE----RRRKEEEERRRAEEEKRRVEREQEYIRR------QLEEEQRH 478
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 15/133 (11%)
Query: 42 VNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQ--RKVHEARAGVLAER-KALKD 98
VN+P F+ ++ Q ++ ALR + + + Q R+ E + +LAER K ++
Sbjct: 344 VNVPGESTLRRDFLRLQ--QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQ 401
Query: 99 AAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVL 158
E R + + + RR E R RQ+EREQ +R+ E+ R+ EE++ +RKE E
Sbjct: 402 QKEQRRRL---EEQQRREREAR----RQQEREQRRREQ-EEKRRLEELER--RRKEEEER 451
Query: 159 QLQEEVKNFITRE 171
+ EE K + RE
Sbjct: 452 RRAEEEKRRVERE 464
Score = 42.4 bits (98), Expect = 3e-04
Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 15/109 (13%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLH 117
E Y+ R R+E E +R++ E + ER+A + + RE Q E RRL
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQR---REREARRQ--QEREQRRREQEEKRRLE 439
Query: 118 ELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKN 166
EL R+ + E+E+R+A E+ R+ E Q + +R QL+EE ++
Sbjct: 440 ELE----RRRKEEEERRRAEEEKRRVEREQEYIRR------QLEEEQRH 478
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 43.1 bits (100), Expect = 2e-04
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 16/141 (11%)
Query: 36 KSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKA 95
K+K ER+ A A + E +Q A R+ ++ Q++ E R L ++K
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL---QQEEEERRHQELLQKKK 668
Query: 96 ------LKDAAEHRELMAWNQAENR----RLHELRIARLRQEEREQEQRQALEQARKAEE 145
L+ AAE + L + E R R E R R++ER +++RQ EQ R+ E+
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Query: 146 VQAWAQR--KERE-VLQLQEE 163
+ A+R +ERE L+LQ+E
Sbjct: 729 ERLQAERELQEREKALRLQKE 749
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/165 (19%), Positives = 68/165 (41%), Gaps = 14/165 (8%)
Query: 27 RKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEAR 86
R+ + + + ++E V + + ER + ++ + + +++ K +A+
Sbjct: 555 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 614
Query: 87 AGVLAERKALKDAA--------------EHRELMAWNQAENRRLHELRIARLRQEEREQE 132
LAE KA K AA E + W Q E + + ++EE ++
Sbjct: 615 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 674
Query: 133 QRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARV 177
R+A E R AE+ + + +ER + +E+ + R E ++
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719
Score = 39.3 bits (90), Expect = 0.002
Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 18/157 (11%)
Query: 36 KSKIERVNMPPAVDPAEFFVLMERYQ----HYRQTVRALRMEFVSE-VQRKVHEARAGVL 90
KS I+R N P +DP FV ER + ++ LR + V E +R++ E + L
Sbjct: 517 KSFIKR-NTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK---L 572
Query: 91 AERKALKDAAEHRELMAWNQAENRRLHELRIARLRQE-EREQEQRQALEQ------ARKA 143
+ L+ + RE + + E ++ E + A++ ++ E+ +E+R A E+ A+K
Sbjct: 573 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632
Query: 144 EEVQAWAQRKE--REVLQLQEEVKNFITRENLEARVE 178
EEV+A +++E R + LQ+E + +E L+ + E
Sbjct: 633 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669
Score = 36.6 bits (83), Expect = 0.015
Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 7/165 (4%)
Query: 28 KTRHDPLAKSKIERVNMPPAVDPAEFFVLME----RYQHYRQTVRALRMEFVSEVQRKVH 83
K + + LA+ K ++ ++ E E R + +Q R + + + +++
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 671
Query: 84 EARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEER---EQEQRQALEQA 140
+ R AE K L + E + + RR E R R++ER EQE+R+ E+
Sbjct: 672 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 731
Query: 141 RKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSRK 185
+ E+Q + + QLQ E++ +E + E L +
Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776
Score = 28.1 bits (61), Expect = 5.5
Identities = 19/92 (20%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 97 KDAAEHRELMAWNQAENRRLHELRI---ARLRQEEREQEQRQALEQARKAEEVQAWAQRK 153
K+ AE + + RRL E+++ RLR+ + +E+ + +++ +K + Q +AQ
Sbjct: 548 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 607
Query: 154 EREVLQLQEEVKNFITRENLEARVEAALDSRK 185
E+ +E + ++ A+ +++R+
Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 43.1 bits (100), Expect = 2e-04
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 16/141 (11%)
Query: 36 KSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKA 95
K+K ER+ A A + E +Q A R+ ++ Q++ E R L ++K
Sbjct: 608 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL---QQEEEERRHQELLQKKK 664
Query: 96 ------LKDAAEHRELMAWNQAENR----RLHELRIARLRQEEREQEQRQALEQARKAEE 145
L+ AAE + L + E R R E R R++ER +++RQ EQ R+ E+
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Query: 146 VQAWAQR--KERE-VLQLQEE 163
+ A+R +ERE L+LQ+E
Sbjct: 725 ERLQAERELQEREKALRLQKE 745
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/165 (19%), Positives = 68/165 (41%), Gaps = 14/165 (8%)
Query: 27 RKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEAR 86
R+ + + + ++E V + + ER + ++ + + +++ K +A+
Sbjct: 551 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
Query: 87 AGVLAERKALKDAA--------------EHRELMAWNQAENRRLHELRIARLRQEEREQE 132
LAE KA K AA E + W Q E + + ++EE ++
Sbjct: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Query: 133 QRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARV 177
R+A E R AE+ + + +ER + +E+ + R E ++
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
Score = 37.0 bits (84), Expect = 0.012
Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 12/118 (10%)
Query: 65 QTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWN--QAENRRLHELRIA 122
+ VR LR F+ VQR A R +K + + + + E +RL LR
Sbjct: 487 KVVRPLRT-FLHTVQRN-QMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLR-- 542
Query: 123 RLRQEEREQEQRQALEQ--ARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVE 178
R+EE EQ +RQ +E+ R+ EEV+ + + R+VLQ +E V+ +E + ++E
Sbjct: 543 --RKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM--KEEKKKQIE 596
Score = 36.6 bits (83), Expect = 0.015
Identities = 44/155 (28%), Positives = 82/155 (52%), Gaps = 18/155 (11%)
Query: 36 KSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRA--LRMEFVSE-VQRKVHEARAGVLAE 92
KS I+R N P +DP E +R ++ R+ A LR + V E +R++ E + L
Sbjct: 517 KSFIKR-NTPLRMDPKE--KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK---LKR 570
Query: 93 RKALKDAAEHRELMAWNQAENRRLHELRIARLRQE-EREQEQRQALEQ------ARKAEE 145
+ L+ + RE + + E ++ E + A++ ++ E+ +E+R A E+ A+K EE
Sbjct: 571 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
Query: 146 VQAWAQRKE--REVLQLQEEVKNFITRENLEARVE 178
V+A +++E R + LQ+E + +E L+ + E
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
Score = 36.6 bits (83), Expect = 0.015
Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 7/165 (4%)
Query: 28 KTRHDPLAKSKIERVNMPPAVDPAEFFVLME----RYQHYRQTVRALRMEFVSEVQRKVH 83
K + + LA+ K ++ ++ E E R + +Q R + + + +++
Sbjct: 608 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 667
Query: 84 EARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEER---EQEQRQALEQA 140
+ R AE K L + E + + RR E R R++ER EQE+R+ E+
Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
Query: 141 RKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSRK 185
+ E+Q + + QLQ E++ +E + E L +
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 42.7 bits (99), Expect = 2e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 6/106 (5%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
++ ALR + + + QR+ E + +LAER+ K E +E + + RR ELR +
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQ--KRIEEQKEQRRRLEEQQRREKELRKQQ 419
Query: 124 LRQEERE-QEQRQALEQARKAEEVQAWAQR---KEREVLQLQEEVK 165
R++ R +EQ + E+ R+AE Q + ++ ++R+ +LQ ++K
Sbjct: 420 EREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLK 465
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 92 ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEV---QA 148
E + D+ E ++ R LR+ +E E +RQ LEQ ++ E Q
Sbjct: 328 EEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQL 387
Query: 149 WAQRKEREVLQLQEEVKNFI---TRENLEARVEAALDSRKNYNWAITRE 194
A+R++R ++ Q+E + + R E R + + R++Y + RE
Sbjct: 388 LAERQKR--IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 42.7 bits (99), Expect = 2e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 6/106 (5%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
++ ALR + + + QR+ E + +LAER+ K E +E + + RR ELR +
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQ--KRIEEQKEQRRRLEEQQRREKELRKQQ 419
Query: 124 LRQEERE-QEQRQALEQARKAEEVQAWAQR---KEREVLQLQEEVK 165
R++ R +EQ + E+ R+AE Q + ++ ++R+ +LQ ++K
Sbjct: 420 EREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLK 465
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 92 ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEV---QA 148
E + D+ E ++ R LR+ +E E +RQ LEQ ++ E Q
Sbjct: 328 EEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQL 387
Query: 149 WAQRKEREVLQLQEEVKNFI---TRENLEARVEAALDSRKNYNWAITRE 194
A+R++R ++ Q+E + + R E R + + R++Y + RE
Sbjct: 388 LAERQKR--IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 42.7 bits (99), Expect = 2e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 6/106 (5%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
++ ALR + + + QR+ E + +LAER+ K E +E + + RR ELR +
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQ--KRIEEQKEQRRRLEEQQRREKELRKQQ 419
Query: 124 LRQEERE-QEQRQALEQARKAEEVQAWAQR---KEREVLQLQEEVK 165
R++ R +EQ + E+ R+AE Q + ++ ++R+ +LQ ++K
Sbjct: 420 EREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLK 465
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 92 ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEV---QA 148
E + D+ E ++ R LR+ +E E +RQ LEQ ++ E Q
Sbjct: 328 EEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQL 387
Query: 149 WAQRKEREVLQLQEEVKNFI---TRENLEARVEAALDSRKNYNWAITRE 194
A+R++R ++ Q+E + + R E R + + R++Y + RE
Sbjct: 388 LAERQKR--IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 42.7 bits (99), Expect = 2e-04
Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 6/106 (5%)
Query: 64 RQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIAR 123
++ ALR + + + QR+ E + +LAER+ K E +E + + RR ELR +
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQ--KRIEEQKEQRRRLEEQQRREKELRKQQ 419
Query: 124 LRQEERE-QEQRQALEQARKAEEVQAWAQR---KEREVLQLQEEVK 165
R++ R +EQ + E+ R+AE Q + ++ ++R+ +LQ ++K
Sbjct: 420 EREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLK 465
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 92 ERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEV---QA 148
E + D+ E ++ R LR+ +E E +RQ LEQ ++ E Q
Sbjct: 328 EEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQL 387
Query: 149 WAQRKEREVLQLQEEVKNFI---TRENLEARVEAALDSRKNYNWAITRE 194
A+R++R ++ Q+E + + R E R + + R++Y + RE
Sbjct: 388 LAERQKR--IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 42.7 bits (99), Expect = 2e-04
Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 2/131 (1%)
Query: 58 ERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAE--RKALKDAAEHRELMAWNQAENRR 115
E+ + R+ L + E+ ++V E R E R+ + A +E QAE R
Sbjct: 495 EKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERA 554
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEA 175
L E A Q ++E+E R E R +E + QR+E+E L+ ++ ++ + R
Sbjct: 555 LREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTE 614
Query: 176 RVEAALDSRKN 186
+ ++N
Sbjct: 615 ATDKKTSDQRN 625
Score = 29.3 bits (64), Expect = 2.4
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 15/79 (18%)
Query: 111 AENRRLHELRIARLRQEEREQE-----------QRQALEQARKAEE----VQAWAQRKER 155
AE RRL + + +E REQE QR A E+ + EE ++A R++
Sbjct: 484 AEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKE 543
Query: 156 EVLQLQEEVKNFITRENLE 174
E LQ Q E + RE E
Sbjct: 544 EQLQRQAEERALREREEAE 562
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/126 (23%), Positives = 50/126 (39%), Gaps = 18/126 (14%)
Query: 70 LRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEER 129
LR++ + R+ E R LA R+ + W + E R +++R
Sbjct: 61 LRVDDRQRLARERREEREKQLAARE-----------IVWLEREERARQHYEKHLEERKKR 109
Query: 130 EQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSRKNYNW 189
+EQRQ E+ R A E K R+ L+ +E + R +E R + ++W
Sbjct: 110 LEEQRQKEERRRAAVE------EKRRQRLEEDKERHEAVVRRTME-RSQKPKQKHNRWSW 162
Query: 190 AITREG 195
+ G
Sbjct: 163 GGSLHG 168
Score = 28.1 bits (61), Expect = 5.5
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 8/57 (14%)
Query: 123 RLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEA 179
RL +E+RE+E+R+ EQ EE++ R++RE L + + RE R+EA
Sbjct: 488 RLAREQREKEERERREQ----EELE----RQKREELAQRVAEERTTRREEESRRLEA 536
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 42.7 bits (99), Expect = 2e-04
Identities = 35/134 (26%), Positives = 64/134 (47%), Gaps = 7/134 (5%)
Query: 54 FVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAEN 113
FV + Q +R+ LR+E +S Q+KV E R +A + L R+ + Q +
Sbjct: 148 FVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELS-----RQKLVEEQMFS 202
Query: 114 RRLHELRIARLRQEERE-QEQRQALEQARKAEEVQAWAQRKEREVLQ-LQEEVKNFITRE 171
+ E R+A+ ++E +E + Q++ +E R Q + + +R+ Q L+EE +
Sbjct: 203 KLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESN 262
Query: 172 NLEARVEAALDSRK 185
N + + E D K
Sbjct: 263 NAQIKHENEQDMLK 276
Score = 29.6 bits (65), Expect = 1.9
Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
Query: 56 LMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRR 115
L ER +H +Q R + + VQR + + L++ A+ ++ + ++
Sbjct: 292 LQERIEHIQQEYRDEQDLNMKLVQRALQD-----------LQEEADKKKQKREDMIREQK 340
Query: 116 LHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRE 171
++ +A+ R+EE+ QE+ E R EE +A ++ + L+L++E + + E
Sbjct: 341 IYHKYLAQRREEEKAQEK----EFDRILEEDKAKKLAEKDKELRLEKEARRQLVDE 392
>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 630
Score = 42.4 bits (98), Expect = 3e-04
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 101 EHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQL 160
+++ + NQ + R+ E +QEER QEQ ++L+Q K + V + + LQL
Sbjct: 328 KNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQL 387
Query: 161 QEEVKNF---ITRENLEA 175
+++VK + E+LEA
Sbjct: 388 EQQVKELQEKLGEEHLEA 405
>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 42.4 bits (98), Expect = 3e-04
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 101 EHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQL 160
+++ + NQ + R+ E +QEER QEQ ++L+Q K + V + + LQL
Sbjct: 328 KNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQL 387
Query: 161 QEEVKNF---ITRENLEA 175
+++VK + E+LEA
Sbjct: 388 EQQVKELQEKLGEEHLEA 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.130 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,158,606
Number of Sequences: 37866
Number of extensions: 301126
Number of successful extensions: 6576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 465
Number of HSP's that attempted gapping in prelim test: 2920
Number of HSP's gapped (non-prelim): 2498
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.