Search of human proteins with 14210532

Search of human proteins with 14210532

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
         (934 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...  1900   0.0  
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...  1821   0.0  
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...  1047   0.0  
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...  1011   0.0  
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...  1009   0.0  
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...   973   0.0  
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]   839   0.0  
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   295   2e-79
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   289   7e-78
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   285   2e-76
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   282   1e-75
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      271   2e-72
gi|4505531 oxysterol binding protein [Homo sapiens]                   270   5e-72
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   115   1e-25
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   115   1e-25
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   115   1e-25
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...   100   1e-20
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...    99   1e-20
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    99   1e-20
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    99   1e-20
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    99   1e-20
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...    99   1e-20
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...    99   1e-20
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...    99   1e-20
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    98   3e-20
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    98   3e-20
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           80   9e-15
gi|217416392 pleckstrin homology domain containing, family H (wi...    57   6e-08
gi|55741447 pleckstrin homology domain containing, family H (wit...    49   2e-05
gi|83716021 GRB2-associated binding protein family, member 4 [Ho...    42   0.003

>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 1900 bits (4922), Expect = 0.0
 Identities = 934/934 (100%), Positives = 934/934 (100%)

Query: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
           MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP
Sbjct: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60

Query: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
           VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK
Sbjct: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120

Query: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
           APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR
Sbjct: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180

Query: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT
Sbjct: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240

Query: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
           CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN
Sbjct: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300

Query: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
           CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH
Sbjct: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360

Query: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
           LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM
Sbjct: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420

Query: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480
           ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV
Sbjct: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480

Query: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540
           ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ
Sbjct: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540

Query: 541 ILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQ 600
           ILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQ
Sbjct: 541 ILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQ 600

Query: 601 HLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR 660
           HLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR
Sbjct: 601 HLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR 660

Query: 661 EDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKY 720
           EDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKY
Sbjct: 661 EDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKY 720

Query: 721 GDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQG 780
           GDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQG
Sbjct: 721 GDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQG 780

Query: 781 VVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDP 840
           VVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDP
Sbjct: 781 VVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDP 840

Query: 841 VLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKK 900
           VLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKK
Sbjct: 841 VLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKK 900

Query: 901 VIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
           VIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
Sbjct: 901 VIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 1821 bits (4718), Expect = 0.0
 Identities = 900/926 (97%), Positives = 901/926 (97%), Gaps = 25/926 (2%)

Query: 34  QSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM 93
           +SIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM
Sbjct: 13  RSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFM 72

Query: 94  LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD 153
           LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD
Sbjct: 73  LKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLD 132

Query: 154 TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 213
           TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV
Sbjct: 133 TEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 192

Query: 214 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV 273
           SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV
Sbjct: 193 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLV 252

Query: 274 ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQ---- 329
           ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQ    
Sbjct: 253 ELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPP 312

Query: 330 ---------------------VPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS 368
                                VPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS
Sbjct: 313 AKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESS 372

Query: 369 TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS 428
           TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS
Sbjct: 373 TDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLS 432

Query: 429 QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM 488
           QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM
Sbjct: 433 QALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSM 492

Query: 489 SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG 548
           SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG
Sbjct: 493 SESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTG 552

Query: 549 GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY 608
           GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY
Sbjct: 553 GAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEY 612

Query: 609 SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF 668
           SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF
Sbjct: 613 SELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFF 672

Query: 669 SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK 728
           SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK
Sbjct: 673 SEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNK 732

Query: 729 VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK 788
           VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK
Sbjct: 733 VTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGK 792

Query: 789 AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP 848
           AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP
Sbjct: 793 AVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPP 852

Query: 849 TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE 908
           TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE
Sbjct: 853 TDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQRE 912

Query: 909 AWVSNDTYWELRKDPGFSKVDSPVLW 934
           AWVSNDTYWELRKDPGFSKVDSPVLW
Sbjct: 913 AWVSNDTYWELRKDPGFSKVDSPVLW 938


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 1047 bits (2708), Expect = 0.0
 Identities = 527/937 (56%), Positives = 679/937 (72%), Gaps = 53/937 (5%)

Query: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32

Query: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85

Query: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145

Query: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202

Query: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP    +Q  
Sbjct: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGG 261

Query: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
             +  KK+KR  RRWR++++ KD K  LQVP      PVRLHSSNPNL + ++F    ++
Sbjct: 262 SFESPKKEKRSHRRWRSRAIGKDAKGTLQVP-KPFSGPVRLHSSNPNL-STLDFGEEKNY 319

Query: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 320 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 377

Query: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQ 478
             L+ +LS AL QN +L+ RL RIH+ES++ D   S  +  S D   E+     +  L  
Sbjct: 378 IGLKNALSSALAQNTDLKERLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVH 434

Query: 479 QVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNIS 538
           Q++NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  
Sbjct: 435 QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE 494

Query: 539 RQILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN 597
           RQ L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLN
Sbjct: 495 RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN 554

Query: 598 TLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYE 657
           TLQ LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYE
Sbjct: 555 TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE 614

Query: 658 CIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717
           CIREDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V L
Sbjct: 615 CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 674

Query: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNE 777
           P +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E
Sbjct: 675 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE 734

Query: 778 VQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNE 837
           ++G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE
Sbjct: 735 IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE 794

Query: 838 LDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKF 897
           +DP  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+F
Sbjct: 795 MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF 854

Query: 898 FKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
           F+K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 855 FRKSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 887


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 515/935 (55%), Positives = 661/935 (70%), Gaps = 85/935 (9%)

Query: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32

Query: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85

Query: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145

Query: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202

Query: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP    +Q  
Sbjct: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGG 261

Query: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
             +  KK+KR  RRWR++++ KD K  LQVP      PVRLHSSNPNL + ++F    ++
Sbjct: 262 SFESPKKEKRSHRRWRSRAIGKDAKGTLQVP-KPFSGPVRLHSSNPNL-STLDFGEEKNY 319

Query: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 320 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 377

Query: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480
             L+ +LS                 SE+             S DE    +H       Q+
Sbjct: 378 IGLKNALS-----------------SEN-------------SRDENRALVH-------QL 400

Query: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540
           +NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ
Sbjct: 401 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 460

Query: 541 ILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL 599
            L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTL
Sbjct: 461 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 520

Query: 600 QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI 659
           Q LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECI
Sbjct: 521 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 580

Query: 660 REDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719
           REDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP 
Sbjct: 581 REDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640

Query: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779
           +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++
Sbjct: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700

Query: 780 GVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELD 839
           G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+D
Sbjct: 701 GTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMD 760

Query: 840 PVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFK 899
           P  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+
Sbjct: 761 PSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 820

Query: 900 KVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
           K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 821 KSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 851


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 1009 bits (2610), Expect = 0.0
 Identities = 516/937 (55%), Positives = 662/937 (70%), Gaps = 84/937 (8%)

Query: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32

Query: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85

Query: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145

Query: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202

Query: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP        
Sbjct: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAIN----- 256

Query: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
                                    IQ+  PFS    PVRLHSSNPNL + ++F    ++
Sbjct: 257 ------------------------AIQVPKPFSG---PVRLHSSNPNL-STLDFGEEKNY 288

Query: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 289 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 346

Query: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQ 478
             L+ +LS AL QN +L+ RL RIH+ES++ D   S  +  S D   E+     +  L  
Sbjct: 347 IGLKNALSSALAQNTDLKERLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVH 403

Query: 479 QVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNIS 538
           Q++NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  
Sbjct: 404 QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE 463

Query: 539 RQILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN 597
           RQ L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLN
Sbjct: 464 RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN 523

Query: 598 TLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYE 657
           TLQ LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYE
Sbjct: 524 TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE 583

Query: 658 CIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717
           CIREDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V L
Sbjct: 584 CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 643

Query: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNE 777
           P +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E
Sbjct: 644 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE 703

Query: 778 VQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNE 837
           ++G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE
Sbjct: 704 IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE 763

Query: 838 LDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKF 897
           +DP  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+F
Sbjct: 764 MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF 823

Query: 898 FKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
           F+K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 824 FRKSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 856


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score =  973 bits (2515), Expect = 0.0
 Identities = 504/935 (53%), Positives = 644/935 (68%), Gaps = 116/935 (12%)

Query: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32

Query: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85

Query: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145

Query: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202

Query: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP        
Sbjct: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAIN----- 256

Query: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
                                    IQ+  PFS    PVRLHSSNPNL + ++F    ++
Sbjct: 257 ------------------------AIQVPKPFSG---PVRLHSSNPNL-STLDFGEEKNY 288

Query: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 289 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 346

Query: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480
             L+ +LS                 SE+             S DE    +H       Q+
Sbjct: 347 IGLKNALS-----------------SEN-------------SRDENRALVH-------QL 369

Query: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540
           +NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ
Sbjct: 370 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 429

Query: 541 ILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL 599
            L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTL
Sbjct: 430 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 489

Query: 600 QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI 659
           Q LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECI
Sbjct: 490 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 549

Query: 660 REDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719
           REDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP 
Sbjct: 550 REDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609

Query: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779
           +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++
Sbjct: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669

Query: 780 GVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELD 839
           G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+D
Sbjct: 670 GTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMD 729

Query: 840 PVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFK 899
           P  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+
Sbjct: 730 PSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 789

Query: 900 KVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
           K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 790 KSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 820


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score =  839 bits (2168), Expect = 0.0
 Identities = 441/890 (49%), Positives = 583/890 (65%), Gaps = 60/890 (6%)

Query: 49  PSVSRQLLEPEPVPLSKEADSWEIIEG--LKIGQTNVQKPDKHEGFMLKKRKWPLKGWHK 106
           P +       +P    + ++ WE++E   +++G   V  P++ EG +LKKRKWPLKGWHK
Sbjct: 9   PFLPESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-PERQEGHLLKKRKWPLKGWHK 67

Query: 107 RFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQ 166
           R+FVL++G+L Y+    DI KGK+HGSIDV LSVMSI KKA+RIDLDTE++IYHLK+KSQ
Sbjct: 68  RYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQ 127

Query: 167 DWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFP 226
           D F +WV++LR HRL  + ++ R    ++ H       A+   AA  S + G + P    
Sbjct: 128 DLFQSWVAQLRAHRLAHRLDMPRGSLPSTAH--RKVPGAQLPTAATASALPG-LGP---- 180

Query: 227 WQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQ 286
                             + KV++WL+DS+ +DRC+ +L+ CQ  L EL +LLQ+LE L 
Sbjct: 181 ------------------REKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLH 222

Query: 287 RTQSAPNFTDMQANCV-DISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSN 345
           R  SAP     QA+   +  KK KR +R W T+S +KD  I             RLH S 
Sbjct: 223 RIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKDDTIG---------RVGRLHGSV 273

Query: 346 PNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQ 405
           PNL   +E +        P    TDY  LQ  F  +AQKVHS L S   ++ +E+++L+ 
Sbjct: 274 PNLSRYLESRDSSGTRGLP---PTDYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRD 330

Query: 406 MVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDE 465
           M     H     ++M     S  Q             R+HS S   D         +P+E
Sbjct: 331 M-----HQGSELSRMGVSEASTGQ------------RRLHSLSTSSDTTADSFSSLNPEE 373

Query: 466 AGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDE-SYISDVSD 524
                     L+ Q++  S LS+++S +EFFDA EVLLSASSSENE S++E S  S+++ 
Sbjct: 374 QEALYMKGRELTPQLSQTSILSLADSHTEFFDACEVLLSASSSENEGSEEEESCTSEITT 433

Query: 525 NISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLS 584
           ++SE+   +     R    G + G      RR CLPA     ++++LWNILRNNIGKDLS
Sbjct: 434 SLSEEMLDLR-GAERCQKGGCVPGRPMGPPRRRCLPAASGPGADVSLWNILRNNIGKDLS 492

Query: 585 KVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAG 644
           KVSMPV+LNEPLNTLQ LCEE+EYS LLD+AS   DP ERMV +AAFAVS Y STY RAG
Sbjct: 493 KVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAG 552

Query: 645 SKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKS 704
            KPFNPVLGETYEC R D+GFRF SEQVSHHPPISACH ES+NF FWQD++WKNKFWGKS
Sbjct: 553 CKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKS 612

Query: 705 MEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLT 764
           +EI+PVGT+NV LP++GD++ WNKVT+CIHN+LSG+RWIEHYGEV IRNT+ S C CK+T
Sbjct: 613 LEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKIT 672

Query: 765 FVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYEL 824
           F K  YW+SN++EVQG V+ + G+ ++RLFGKWHEGLY G  P  +CIW+P SMP ++E 
Sbjct: 673 FCKAKYWSSNVHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHER 732

Query: 825 YYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRR 884
            +GFT+FA+ELNEL   LK  LP TD R RPDQR+LEEGN++AA ++K+R+E+LQR RR+
Sbjct: 733 NFGFTQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRK 792

Query: 885 YMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
            MEENN+ H  +FF++  D++ +E WV+N+TYW LR +PG+  +D  VLW
Sbjct: 793 VMEENNIVHQARFFRRQTDSSGKEWWVTNNTYWRLRAEPGYGNMDGAVLW 842


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  295 bits (754), Expect = 2e-79
 Identities = 182/493 (36%), Positives = 257/493 (52%), Gaps = 59/493 (11%)

Query: 476 LSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVAD 535
           L Q +   S  +   S  EF+DA    LS S SE   S  E+     + +  E+   +  
Sbjct: 457 LEQSLVKGSPPASILSEDEFYDA----LSDSESERSLSRLEAV---TARSFEEEGEHLGS 509

Query: 536 NISRQILNGELTGG-AFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVE 591
              R     +  GG A  NG    R  LP+P    ++ ++W+ILR  IG +LSK++MPV 
Sbjct: 510 RKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVI 569

Query: 592 LNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPV 651
            NEPL+ LQ L E ME++ L+ KAS   DP ERM  VAAFAVS   S + R G KPFNP+
Sbjct: 570 FNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPL 628

Query: 652 LGETYECIREDKGFRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILP 709
           LGETYE +R+D GFR  SEQVSHHPPISA H E  N  F+F   I  K KFWGKS+E  P
Sbjct: 629 LGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEP 688

Query: 710 VGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVN 769
            GT+ + L ++ + Y W   T C+HNI+ G+ WIE YG V I N K+    C L F    
Sbjct: 689 KGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCG 747

Query: 770 YWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLY--------------------------- 802
            +   +++V+G + D+  K +  L+GKW E LY                           
Sbjct: 748 LFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQM 807

Query: 803 ----------------CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLL 846
                             + P +  +WR    P N    Y FT FA+ LNE+D  ++ ++
Sbjct: 808 STSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVI 867

Query: 847 PPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-N 905
           P TD R RPD R +E G ++ A+ EK+R+EE QR+ R+   ++  +   ++F +  +  N
Sbjct: 868 PKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYN 927

Query: 906 QREAWVSNDTYWE 918
             + W+ + +YW+
Sbjct: 928 GAQDWIYSGSYWD 940


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  289 bits (740), Expect = 7e-78
 Identities = 164/420 (39%), Positives = 230/420 (54%), Gaps = 51/420 (12%)

Query: 548 GGAFRNG---RRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 604
           G A  NG    R  LP+P    ++ ++W+ILR  IG +LSK++MPV  NEPL+ LQ L E
Sbjct: 10  GDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTE 69

Query: 605 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKG 664
            ME++ L+ KAS   DP ERM  VAAFAVS   S + R G KPFNP+LGETYE +R+D G
Sbjct: 70  YMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLG 128

Query: 665 FRFFSEQVSHHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 722
           FR  SEQVSHHPPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L ++ +
Sbjct: 129 FRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNE 188

Query: 723 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVV 782
            Y W   T C+HNI+ G+ WIE YG V I N K+    C L F     +   +++V+G +
Sbjct: 189 AYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTG-DKCVLNFKPCGLFGKELHKVEGYI 247

Query: 783 IDQEGKAVYRLFGKWHEGLY---------------------------------------- 802
            D+  K +  L+GKW E LY                                        
Sbjct: 248 QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPD 307

Query: 803 ---CGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 859
                + P +  +WR    P N    Y FT FA+ LNE+D  ++ ++P TD R RPD R 
Sbjct: 308 SESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRA 367

Query: 860 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDA-NQREAWVSNDTYWE 918
           +E G ++ A+ EK+R+EE QR+ R+   ++  +   ++F +  +  N  + W+ + +YW+
Sbjct: 368 MENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWD 427


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  285 bits (728), Expect = 2e-76
 Identities = 171/453 (37%), Positives = 235/453 (51%), Gaps = 57/453 (12%)

Query: 494 EFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRN 553
           EFFDA     S +SS  E S+    ++ + D  +  N  +     R      +       
Sbjct: 6   EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGI------Q 58

Query: 554 GRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLD 613
             R  LPAP    S+ ++W IL+  +G +LSK++MP+  NEPL+ LQ + E ME+  L+ 
Sbjct: 59  KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118

Query: 614 KASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVS 673
           +AS    P ERM  VAAFAVS   S + R G KPFNP+LGETYE IRED GFRF SEQVS
Sbjct: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 177

Query: 674 HHPPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTT 731
           HHPPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L K+ + Y W   T 
Sbjct: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237

Query: 732 CIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVY 791
           C+HN++ G+ WIE YG V I N ++    C L F     +   +++V+G + D+  K ++
Sbjct: 238 CVHNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 296

Query: 792 RLFGKWHEGLY----------------------------------------------CGV 805
            ++GKW E L+                                                V
Sbjct: 297 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 356

Query: 806 APSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNL 865
            P +K +WR  + P N    Y FT F + LNEL+  ++  LPPTD R RPD R +E GN+
Sbjct: 357 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 416

Query: 866 EAAASEKQRVEELQRSRRRYMEENNLEHIPKFF 898
           + A+ EK+R+EE QR  RR   +   E   ++F
Sbjct: 417 DLASQEKERLEEKQREARRERAKEEAEWQTRWF 449


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  282 bits (721), Expect = 1e-75
 Identities = 158/391 (40%), Positives = 214/391 (54%), Gaps = 50/391 (12%)

Query: 556 RACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKA 615
           R  LPAP    S+ ++W IL+  +G +LSK++MP+  NEPL+ LQ + E ME+  L+ +A
Sbjct: 49  RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA 108

Query: 616 SETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHH 675
           S    P ERM  VAAFAVS   S + R G KPFNP+LGETYE IRED GFRF SEQVSHH
Sbjct: 109 SCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVSHH 167

Query: 676 PPISACHCESKN--FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCI 733
           PPISA H E  N  F+F   I  K KFWGKS+E  P GT+ + L K+ + Y W   T C+
Sbjct: 168 PPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCV 227

Query: 734 HNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRL 793
           HN++ G+ WIE YG V I N ++    C L F     +   +++V+G + D+  K ++ +
Sbjct: 228 HNVIIGKLWIEQYGTVEILNHRTG-HKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMI 286

Query: 794 FGKWHEGLY----------------------------------------------CGVAP 807
           +GKW E L+                                                V P
Sbjct: 287 YGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIP 346

Query: 808 SAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEA 867
            +K +WR  + P N    Y FT F + LNEL+  ++  LPPTD R RPD R +E GN++ 
Sbjct: 347 GSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDL 406

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFF 898
           A+ EK+R+EE QR  RR   +   E   ++F
Sbjct: 407 ASQEKERLEEKQREARRERAKEEAEWQTRWF 437


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  271 bits (694), Expect = 2e-72
 Identities = 183/475 (38%), Positives = 268/475 (56%), Gaps = 53/475 (11%)

Query: 487 SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGE- 545
           S  +  +E+FDA E   S  +   EA +D S  ++ S   S  + S ADN+    L+G  
Sbjct: 444 SEEDEDTEYFDAMEDSTSFITVITEAKED-SRKAEGSTGTSSVDWSSADNV----LDGAS 498

Query: 546 -LTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 604
            +  G+ +  RR  +P   P+ S +NLW+I++N IG++LS++ MPV  NEPL+ LQ L E
Sbjct: 499 LVPKGSSKVKRRVRIPNK-PNYS-LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTE 556

Query: 605 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-EDK 663
           ++EY  LLDKA       E+M LVAAF+VS Y +T  R  +KPFNP+LGET+E  R +D 
Sbjct: 557 DLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDM 615

Query: 664 GFRFFSEQVSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 722
           G R   EQVSHHPP +A +  SK+ +  WQ+I   +KF GK + I+P+G +++     G+
Sbjct: 616 GLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGN 675

Query: 723 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSN-MNEVQGV 781
           +YVW K T+ +HNI+ G+ WI+  G++ I N K++   C+L F+  +Y++     +V GV
Sbjct: 676 HYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTN-DRCQLKFLPYSYFSKEAARKVTGV 734

Query: 782 VIDQEGKAVYRLFGKWHEGLYCGVAP--------------------SAKCIWRPGSMPTN 821
           V D +GKA Y L G W E + C                        SAK +W+   +P N
Sbjct: 735 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN 794

Query: 822 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQR- 880
            E  Y F+  A+ LNE +    + + PTD+R RPDQR +E+G  + A +EKQR+EE QR 
Sbjct: 795 AENMYYFSELALTLNEHE----EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRL 850

Query: 881 SRRRYME----------ENNLE---HIPKFFKKVIDANQRE-AWVSNDTYWELRK 921
           SRRR +E          E   E   + P +F+K +D    E A V    YWE ++
Sbjct: 851 SRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKE 905



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%)

Query: 87  DKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKK 146
           D  EG++LK   + LKG+ +R+FVL NG+L Y +   ++      G+I++  + +  +  
Sbjct: 183 DSFEGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQGEMAH-TCRGTINLSTAHIDTEDS 240

Query: 147 ARRIDLDTEEHIYHLKVKSQDWFDAWVSKL 176
              I L +    YHLK  S+     W++ L
Sbjct: 241 C-GILLTSGARSYHLKASSEVDRQQWITAL 269


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  270 bits (690), Expect = 5e-72
 Identities = 207/647 (31%), Positives = 318/647 (49%), Gaps = 80/647 (12%)

Query: 318 KSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCAD--IEFQTPPSHLTD---PLESSTDYT 372
           +SVS+  K +LQ       S V   S+  +L A      Q   S L     P ES+    
Sbjct: 197 ESVSQTDKTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIK 256

Query: 373 KLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALN 432
           ++ E   L     ++++ +  + + + +   K+      + +    Q  RL ++L Q   
Sbjct: 257 QVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERD---QRIRLEETLEQLAK 313

Query: 433 QNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESV 492
           Q+  L                     ++P    A    +V     Q  + +  +S  +  
Sbjct: 314 QHNHLERAFR-------------GATVLP----ANTPGNVGSGKDQCCSGKGDMSDEDDE 356

Query: 493 SEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFR 552
           +EFFDA E++    +  ++ +   S IS  S +IS D     +    Q+   E T    +
Sbjct: 357 NEFFDAPEIITMPENLGHKRTG--SNISGASSDISLD-----EQYKHQL---EET----K 402

Query: 553 NGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELL 612
             +R  +P   P+ S +NLW+I++N IGK+LSK+ MPV  NEPL+ LQ L E++EY ELL
Sbjct: 403 KEKRTRIPYK-PNYS-LNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELL 460

Query: 613 DKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-EDKGFRFFSEQ 671
           D+A++ ++  E++  VAAF VS Y +T FR  SKPFNP+LGET+E  R E+ G+R   EQ
Sbjct: 461 DRAAKCENSLEQLCYVAAFTVSSYSTTVFRT-SKPFNPLLGETFELDRLEENGYRSLCEQ 519

Query: 672 VSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVT 730
           VSHHPP +A H ESKN +   Q+I+  +KF GK + I+P+GT++ +    G +Y W KVT
Sbjct: 520 VSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVT 579

Query: 731 TCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNM-NEVQGVVIDQEGKA 789
           T +HNI+ G+ WI+  GE+ I N K+    C L FV  +Y++ ++  +V G V D  GK 
Sbjct: 580 TTVHNIIVGKLWIDQSGEIDIVNHKTG-DKCNLKFVPYSYFSRDVARKVTGEVTDPSGKV 638

Query: 790 VYRLFGKWHEGLYC-GVAP------------------SAKCIWRPGSMPTNYELYYGFTR 830
            + L G W E + C  V P                  S   +W+   +P N E  Y F+ 
Sbjct: 639 HFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSE 698

Query: 831 FAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYME--- 887
            A+ LN      +    PTD+R RPDQR +E G  + A +EKQR+EE QR  R+  E   
Sbjct: 699 LALTLN----AWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEA 754

Query: 888 ----ENNLEHIPK----FFKKVIDANQREAWVSNDTYWELRKDPGFS 926
               E+   + P     F +K     +    +    YWE ++   +S
Sbjct: 755 MKATEDGTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWS 801



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 24/87 (27%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 90  EGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARR 149
           EG++ K   + +KG+ +R+FVL NG+L Y ++  ++ +    G+I++  + ++++     
Sbjct: 92  EGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCNF 149

Query: 150 IDLDTEEHIYHLKVKSQDWFDAWVSKL 176
           I  +     YHLK  S+     WV+ L
Sbjct: 150 IISNGGAQTYHLKASSEVERQRWVTAL 176


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 503 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 555
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 290 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 344

Query: 556 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 603
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 345 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 404

Query: 604 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 659
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 405 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 463

Query: 660 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 464 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 523

Query: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 775
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 524 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 582

Query: 776 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 833
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 583 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 637

Query: 834 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 893
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 638 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 691

Query: 894 IPKFF 898
            P+ F
Sbjct: 692 KPQLF 696


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 503 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 555
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276

Query: 556 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 603
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336

Query: 604 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 659
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395

Query: 660 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455

Query: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 775
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514

Query: 776 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 833
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569

Query: 834 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 893
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623

Query: 894 IPKFF 898
            P+ F
Sbjct: 624 KPQLF 628


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  115 bits (289), Expect = 1e-25
 Identities = 111/425 (26%), Positives = 188/425 (44%), Gaps = 47/425 (11%)

Query: 503 LSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNG----ELTGGAFRNGR--- 555
           L+ SS EN+A  D+S      +N  E +T   D+ SR+  +G    E  G   R G    
Sbjct: 222 LNGSSLENDAFSDKSE----RENPEESDTETQDH-SRKTESGSDQSETPGAPVRRGTTYV 276

Query: 556 -----------RACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQHLC 603
                       A       + +   +W +L+    G DLS+V +P  + EP + L  L 
Sbjct: 277 EQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLS 336

Query: 604 EEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI---- 659
           +   +++LL +A+  +D Y RM LV  + +SG+     +   KP+NP+LGET+ C     
Sbjct: 337 DYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKP-KGIKKPYNPILGETFRCCWFHP 395

Query: 660 REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717
           + D    + +EQVSHHPP+SA H  ++   F     I  K++F+G S+  L  G   +  
Sbjct: 396 QTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTF 455

Query: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW--NSNM 775
               + Y           IL G   +E  G+VTI   K++    +L F    ++  ++++
Sbjct: 456 LNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNF-QAQLEFKLKPFFGGSTSI 514

Query: 776 NEVQGVVIDQEGKAVYRLFGKWHEGLYCGV--APSAKCIWRPGSMPTNYELYYGFTRFAI 833
           N++ G +   E + +  L G W   ++     + S+   W P        L     +  +
Sbjct: 515 NQISGKITSGE-EVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRL----RQHTV 569

Query: 834 ELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEH 893
            L E   +  + L      ++   R + +G+   A  EK  +EE QR R R  +E+ +  
Sbjct: 570 PLEEQTELESERL------WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPW 623

Query: 894 IPKFF 898
            P+ F
Sbjct: 624 KPQLF 628


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 98/394 (24%), Positives = 164/394 (41%), Gaps = 66/394 (16%)

Query: 565 DTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYER 624
           D  +I L  I +  +G DL+KV +P  + E  + L+   + M + +LL   +    P ER
Sbjct: 395 DQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEER 454

Query: 625 MVLVAAFAVSGYCSTYFRA-GSKPFNPVLGETYECIRE---------------------- 661
           ++    + ++ +      A   KP+NP++GET+ C  E                      
Sbjct: 455 VICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEH 514

Query: 662 ------DKGF--RFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVG 711
                  K +  RF +EQVSHHPPIS   C CE K       +  K+KF G S+ +  +G
Sbjct: 515 PMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIG 574

Query: 712 TLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYW 771
              + L ++G+ YV+   +    +IL+   W+E  G+V+I   K+      +   K  Y 
Sbjct: 575 EGVLRLLEHGEEYVFTLPSAYARSILT-IPWVELGGKVSINCAKTGYSATVIFHTKPFYG 633

Query: 772 NSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRF 831
                    V  +     V +  G+W+                 G++   Y    G T+ 
Sbjct: 634 GKVHRVTAEVKHNPTNTIVCKAHGEWN-----------------GTLEFTYN--NGETK- 673

Query: 832 AIELNELDPVLKDLLP-----PTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRR 884
            I+   L    K + P     P ++R  +R   R+L  G+++AA  +K+ +EE QR   R
Sbjct: 674 VIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEER 733

Query: 885 YMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 918
             E       PK+F       + + WV  +  W+
Sbjct: 734 KRENLRTPWKPKYF-----IQEGDGWVYFNPLWK 762



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 46/205 (22%), Positives = 85/205 (41%), Gaps = 22/205 (10%)

Query: 101 LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARR--IDLDTEE 156
           L+GW  R+FVLD   G+L+Y       +  K  G + +  +++S+  +A    +      
Sbjct: 88  LQGWQNRYFVLDFEAGILQYF-VNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANG 146

Query: 157 HIYHLKVKSQDWFDAWVSKLR---HHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANV 213
            ++ L+         WV++LR    + +   ++   S R  S  + P  +   +SP +  
Sbjct: 147 EMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQR 206

Query: 214 SVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAE----DLAHCQ 269
            +  G       P    +    S PA     +S+ +  L +  EM    E    +L H  
Sbjct: 207 HLSVGA------PGVVTITHHKS-PAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAI 259

Query: 270 SNLV---ELSKLLQNLEILQRTQSA 291
            +L     L+ L Q+L +L+ T +A
Sbjct: 260 ESLPGSGPLTALDQDLLLLKATSAA 284


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 583

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 641

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 642 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 683

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 684 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 725



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 98  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 593

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 594 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 651

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 652 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 693

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 694 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 735



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 98  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 570

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 571 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 628

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 629 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 670

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 671 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 712



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 98  KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
           KW   +KGW  R+FVLD   G+L Y  +   + +G   G + +  +V+ I  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
             ++  +H + +  D  + W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 473

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 474 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 531

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 532 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 573

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 574 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 615


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 418

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 419 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 476

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 477 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 518

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 519 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 560


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 405

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 406 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 463

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 464 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 505

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 506 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 547


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)

Query: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
           S S S  EF+DA E   S SS +   ++S   S ++  S   S       ++++  + NG
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
                 F   + R     A   +     + ++L    +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
             +   + +L    S+  DP +RMV V  + +S + +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
                         + E            F +EQVSHHPPISA    C +K   F   I 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
            K+KF G S+ +  +G   V    Y ++Y+         +IL+   W+E  GE  I  +K
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 405

Query: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
           +      +   K  Y          +    + K+   + G+W+  +Y   A     ++  
Sbjct: 406 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 463

Query: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
                            ++  +L P++K  +   + +   + R L +         +++A
Sbjct: 464 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 505

Query: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
           A   K R+EE QR+  R  +E  ++   + F +       E WV ++
Sbjct: 506 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 547


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 485 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 536
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 268 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 327

Query: 537 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 592
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 328 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 387

Query: 593 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 652
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 388 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 446

Query: 653 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 706
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 447 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 506

Query: 707 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 766
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 507 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 565

Query: 767 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 821
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 566 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 623

Query: 822 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 881
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 624 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 673

Query: 882 RRRYMEENNLEHIPKFFK 899
             R  +  N E   K F+
Sbjct: 674 AARDRKTKNEEWSCKLFE 691


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/438 (24%), Positives = 183/438 (41%), Gaps = 37/438 (8%)

Query: 485 RLSMSESVSEFFDAQEVLLSASSSENEASDDES--------YISDVSDNISEDNTSVADN 536
           +L+ SE   + F  Q++    S  EN+   DES          SD   +  +D++ +   
Sbjct: 310 QLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPE 369

Query: 537 ISRQILNGELTGGAFRNGRRACLPAPCPDTSNIN---LWNILRN-NIGKDLSKVSMPVEL 592
               +     T  +      A   +     S  N   +W +L+    G DLSKV +P  +
Sbjct: 370 PVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFI 429

Query: 593 NEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVL 652
            EP + L  L +   +++ L +A+  ++PY R+  V  + +SG+     +   KP+NP+L
Sbjct: 430 LEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKP-KGLKKPYNPIL 488

Query: 653 GETYECI----REDKGFRFFSEQVSHHPPISACHCESK--NFVFWQDIRWKNKFWGKSME 706
           GET+ C+    R +    + +EQVSHHPPISA +  ++   F     I  K+KF+G S+ 
Sbjct: 489 GETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLS 548

Query: 707 ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFV 766
            +  G   +     G+ YV          IL G   +E  G V I   K+      L F 
Sbjct: 549 AILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAI-LEFK 607

Query: 767 KVNYWNSN--MNEVQGVVIDQEGKAVY-RLFGKWHEGLYC--GVAPSAKCIWRPGSMPTN 821
              +  S+  +N++ G +  + GK V   L G W   ++       +++  W P      
Sbjct: 608 LKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQ 665

Query: 822 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRS 881
           + L     R  ++  E      + L      ++   R +   +   A  EK  +EE QR 
Sbjct: 666 WRL----IRHTVKFEEQGDFESEKL------WQRVTRAINAKDQTEATQEKYVLEEAQRQ 715

Query: 882 RRRYMEENNLEHIPKFFK 899
             R  +  N E   K F+
Sbjct: 716 AARDRKTKNEEWSCKLFE 733


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 81/383 (21%), Positives = 151/383 (39%), Gaps = 64/383 (16%)

Query: 579 IGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCS 638
           +G DL++V +P  + E  + L+   + M + +L    +      +RM+    + ++ +  
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438

Query: 639 TYFRA-GSKPFNPVLGETYECI------------------------------------RE 661
               A   KP+NP++GET+ C                                      +
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498

Query: 662 DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719
               RF +EQVSHHPP+S     C  +       +  K+KF G S+ +  VG   + L +
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558

Query: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779
           +G+ Y ++       +IL+   W+E  G+V++   K+      +TF    ++   ++ V 
Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSVNCAKTGYS-ASITFHTKPFYGGKLHRVT 616

Query: 780 GVVIDQ-EGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNEL 838
             V        V R+ G+W+  L               +       Y   T+ A+    +
Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663

Query: 839 DPVLKDLLPPTDAR--FRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPK 896
            P+ K    P ++R  ++     L E  ++ A   K  +EE QR+  R+  E       K
Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721

Query: 897 FFKKVIDANQREAWVSNDTYWEL 919
           +F K     + + WV +   W++
Sbjct: 722 YFIK-----EGDGWVYHKPLWKI 739


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 19/171 (11%)

Query: 21  SASSSTSSQRDSRQ-----SIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEG 75
           S SSS +S+ DSR      S   ++R  S S+  S S   + P+      E    E    
Sbjct: 630 SRSSSRTSESDSRSRSGPGSPRAMKRGVSLSSVASESDYAIPPDAYSTDTEYSQPE---- 685

Query: 76  LKIGQT-------NVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLD-IQK 127
            K+ +T          +P +  G++LK     +K W +R+FVL  G L Y K+P D I+K
Sbjct: 686 QKLPKTCSSSSDNGKNEPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIRK 744

Query: 128 GKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRH 178
            + H  +    S++    K + + L TE+H Y+L   S +  + W+  L++
Sbjct: 745 PQGHIELSASCSILRGDNK-QTVQLTTEKHTYYLTADSPNILEEWIKVLQN 794


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 40/174 (22%), Positives = 77/174 (44%), Gaps = 33/174 (18%)

Query: 5   EKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLS 64
           ++G+S +  +S   +     + S   D  +  H L+RT+S ST+                
Sbjct: 527 KRGVSMSSLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTD---------------- 570

Query: 65  KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLD 124
                     GL +G  +++K     G++LK     +K W +R+FVL  G + Y K+P D
Sbjct: 571 ----------GLGLGGESLEK----SGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSD 615

Query: 125 IQKGKVHGSIDVGLSVMSIK-KKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLR 177
           + + K  G +D+      ++ + ++   L +E+  Y+L   S    + W+  L+
Sbjct: 616 VIR-KPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668


>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
           sapiens]
          Length = 574

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 32/216 (14%)

Query: 45  SSTEPSVSRQLLEPEPV--PLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLK---KRKW 99
           S   PS SR+L  P+P   PLS    S       + G         + G++ K   ++K 
Sbjct: 2   SLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHV------LYSGWLRKSPPEKKL 55

Query: 100 PLKGWHKRFFVLDNG-------MLKY-----SKAPLDIQKGKVHGSIDVGLSVMSIKKKA 147
            L  W KR+F+L  G       +L+Y     SK PL      +   +DV +++   KK+ 
Sbjct: 56  RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115

Query: 148 RR---IDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTST 204
           ++    D+ T E  ++L  ++++  + WV  +     +RQ E      + S        +
Sbjct: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNIS-SASHGLCS 174

Query: 205 AESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
           + + P+ +   +  + +P S P     P S+ +P T
Sbjct: 175 SPAEPSCSHQHLPQEQEPTSEP-----PVSHCVPPT 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,197,708
Number of Sequences: 37866
Number of extensions: 1649172
Number of successful extensions: 6812
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 6458
Number of HSP's gapped (non-prelim): 323
length of query: 934
length of database: 18,247,518
effective HSP length: 112
effective length of query: 822
effective length of database: 14,006,526
effective search space: 11513364372
effective search space used: 11513364372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.