Search of human proteins with 14165272

Search of human proteins with 14165272

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165272 PTEN induced putative kinase 1 precursor [Homo
sapiens]
         (581 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165272 PTEN induced putative kinase 1 precursor [Homo sapiens]  1170   0.0  
gi|126091095 myotonic dystrophy protein kinase isoform 1 [Homo s...    70   7e-12
gi|126091040 myotonic dystrophy protein kinase isoform 4 [Homo s...    70   7e-12
gi|126131093 myotonic dystrophy protein kinase isoform 3 [Homo s...    70   7e-12
gi|47059024 myotonic dystrophy protein kinase isoform 2 [Homo sa...    70   7e-12
gi|148368962 NKF3 kinase family member [Homo sapiens]                  61   2e-09
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...    60   4e-09
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha...    60   6e-09
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha...    60   6e-09
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom...    59   9e-09
gi|212549756 calcium/calmodulin-dependent protein kinase II delt...    59   1e-08
gi|26667183 calcium/calmodulin-dependent protein kinase II delta...    59   1e-08
gi|212549753 calcium/calmodulin-dependent protein kinase II delt...    59   1e-08
gi|26667186 calcium/calmodulin-dependent protein kinase II delta...    59   1e-08
gi|26667189 calcium/calmodulin-dependent protein kinase II delta...    59   1e-08
gi|26667180 calcium/calmodulin-dependent protein kinase II delta...    59   1e-08
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma...    58   2e-08
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma...    58   2e-08
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma...    58   2e-08
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma...    58   2e-08
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma...    58   2e-08
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...    58   2e-08
gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo sa...    57   4e-08
gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo sa...    57   4e-08
gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [H...    57   5e-08
gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4 [...    57   5e-08
gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3 [...    57   5e-08
gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2 [...    57   5e-08
gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho...    57   6e-08
gi|30039692 NIMA-related kinase 8 [Homo sapiens]                       57   6e-08

>gi|14165272 PTEN induced putative kinase 1 precursor [Homo sapiens]
          Length = 581

 Score = 1170 bits (3028), Expect = 0.0
 Identities = 581/581 (100%), Positives = 581/581 (100%)

Query: 1   MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVG 60
           MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVG
Sbjct: 1   MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVG 60

Query: 61  LGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRR 120
           LGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRR
Sbjct: 61  LGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRR 120

Query: 121 AVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQ 180
           AVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQ
Sbjct: 121 AVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQ 180

Query: 181 NLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQE 240
           NLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQE
Sbjct: 181 NLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQE 240

Query: 241 LVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLP 300
           LVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLP
Sbjct: 241 LVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLP 300

Query: 301 SRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAH 360
           SRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAH
Sbjct: 301 SRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAH 360

Query: 361 RDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVST 420
           RDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVST
Sbjct: 361 RDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVST 420

Query: 421 ARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPP 480
           ARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPP
Sbjct: 421 ARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPP 480

Query: 481 DVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLL 540
           DVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLL
Sbjct: 481 DVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLL 540

Query: 541 ANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL 581
           ANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL
Sbjct: 541 ANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL 581


>gi|126091095 myotonic dystrophy protein kinase isoform 1 [Homo
           sapiens]
          Length = 639

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%)

Query: 314 LFLVMKNYP----CTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNIL 369
           L+LVM+ Y      TL        P+  +A   L +++  +D + + G  HRD+K DNIL
Sbjct: 154 LYLVMEYYVGGDLLTLLSKFGERIPA-EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNIL 212

Query: 370 VELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVI 429
           +    D C  + +ADFG CL   + G      +      G    ++PE+  A  G     
Sbjct: 213 L----DRCGHIRLADFGSCLKLRADGTVRSLVA-----VGTPDYLSPEILQAVGGGPGTG 263

Query: 430 DYS-KADAWAVGAIAYEIFGLVNPFYGQGKAHLESR--SYQE-AQLPALPESVPPDVRQL 485
            Y  + D WA+G  AYE+F    PFY    A    +   Y+E   LP + E VP + R  
Sbjct: 264 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDF 323

Query: 486 VRALL 490
           ++ LL
Sbjct: 324 IQRLL 328


>gi|126091040 myotonic dystrophy protein kinase isoform 4 [Homo
           sapiens]
          Length = 625

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%)

Query: 314 LFLVMKNYP----CTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNIL 369
           L+LVM+ Y      TL        P+  +A   L +++  +D + + G  HRD+K DNIL
Sbjct: 144 LYLVMEYYVGGDLLTLLSKFGERIPA-EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNIL 202

Query: 370 VELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVI 429
           +    D C  + +ADFG CL   + G      +      G    ++PE+  A  G     
Sbjct: 203 L----DRCGHIRLADFGSCLKLRADGTVRSLVA-----VGTPDYLSPEILQAVGGGPGTG 253

Query: 430 DYS-KADAWAVGAIAYEIFGLVNPFYGQGKAHLESR--SYQE-AQLPALPESVPPDVRQL 485
            Y  + D WA+G  AYE+F    PFY    A    +   Y+E   LP + E VP + R  
Sbjct: 254 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDF 313

Query: 486 VRALL 490
           ++ LL
Sbjct: 314 IQRLL 318


>gi|126131093 myotonic dystrophy protein kinase isoform 3 [Homo
           sapiens]
          Length = 624

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%)

Query: 314 LFLVMKNYP----CTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNIL 369
           L+LVM+ Y      TL        P+  +A   L +++  +D + + G  HRD+K DNIL
Sbjct: 144 LYLVMEYYVGGDLLTLLSKFGERIPA-EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNIL 202

Query: 370 VELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVI 429
           +    D C  + +ADFG CL   + G      +      G    ++PE+  A  G     
Sbjct: 203 L----DRCGHIRLADFGSCLKLRADGTVRSLVA-----VGTPDYLSPEILQAVGGGPGTG 253

Query: 430 DYS-KADAWAVGAIAYEIFGLVNPFYGQGKAHLESR--SYQE-AQLPALPESVPPDVRQL 485
            Y  + D WA+G  AYE+F    PFY    A    +   Y+E   LP + E VP + R  
Sbjct: 254 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDF 313

Query: 486 VRALL 490
           ++ LL
Sbjct: 314 IQRLL 318


>gi|47059024 myotonic dystrophy protein kinase isoform 2 [Homo
           sapiens]
          Length = 629

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 18/185 (9%)

Query: 314 LFLVMKNYP----CTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNIL 369
           L+LVM+ Y      TL        P+  +A   L +++  +D + + G  HRD+K DNIL
Sbjct: 144 LYLVMEYYVGGDLLTLLSKFGERIPA-EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNIL 202

Query: 370 VELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVI 429
           +    D C  + +ADFG CL   + G      +      G    ++PE+  A  G     
Sbjct: 203 L----DRCGHIRLADFGSCLKLRADGTVRSLVA-----VGTPDYLSPEILQAVGGGPGTG 253

Query: 430 DYS-KADAWAVGAIAYEIFGLVNPFYGQGKAHLESR--SYQE-AQLPALPESVPPDVRQL 485
            Y  + D WA+G  AYE+F    PFY    A    +   Y+E   LP + E VP + R  
Sbjct: 254 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDF 313

Query: 486 VRALL 490
           ++ LL
Sbjct: 314 IQRLL 318


>gi|148368962 NKF3 kinase family member [Homo sapiens]
          Length = 1746

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 62/217 (28%), Positives = 88/217 (40%), Gaps = 27/217 (12%)

Query: 316  LVMKNYPCT-----LRQYLCVNTPSP----RLAAMMLLQLLEGVDHLVQQGIAHRDLKSD 366
            ++ +  PC      +R  L  +  SP    R   ++LLQL  G++HL    + H DL+ +
Sbjct: 1461 VITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLE 1520

Query: 367  N-ILVELDPDGCPWLVIADFGCCLADESIGLQLP---FSSWYVDRGGNGCLMAPEV---- 418
            N +LV   P G        FG   A+ S     P     S +        L+ PE+    
Sbjct: 1521 NLLLVHYQPGG----TAQGFG--PAEPSPTSSYPTRLIVSNFSQAKQKSHLVDPEILRDQ 1574

Query: 419  STARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESV 478
            S   P       Y K D +  G + YE+  L NPF       L+ R Y  A LP +P   
Sbjct: 1575 SRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPF--DENPELKEREYTRADLPRIPFRS 1632

Query: 479  P--PDVRQLVRALLQREASKRPSARVAANVLHLSLWG 513
            P    ++QL   LL    S+R     A  +L   LWG
Sbjct: 1633 PYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWG 1669


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 51/165 (30%), Positives = 80/165 (48%), Gaps = 20/165 (12%)

Query: 337 RLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNIL-VELDPDGCPWLVIADFGCCLADESIG 395
           R A+ ++ Q+L+ V +L   GI HRDLK +N+L   LD D    ++I+DFG    ++   
Sbjct: 116 RDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDS--KIMISDFGLSKMED--- 170

Query: 396 LQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKA-DAWAVGAIAYEIFGLVNPFY 454
              P S      G  G  +APEV   +P       YSKA D W++G IAY +     PFY
Sbjct: 171 ---PGSVLSTACGTPG-YVAPEVLAQKP-------YSKAVDCWSIGVIAYILLCGYPPFY 219

Query: 455 GQGKAHLESRSYQEAQLPALP--ESVPPDVRQLVRALLQREASKR 497
            +  A L  +  +       P  + +    +  +R L++++  KR
Sbjct: 220 DENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKR 264


>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
           isoform 2 [Homo sapiens]
          Length = 478

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V H  Q G+ HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 112 ASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAA-VKLADFG--LAIEVEGEQ- 167

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 168 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DLWACGVILYILLVGYPPFWDED- 217

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    SKR +A  A
Sbjct: 218 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA 265


>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
           isoform 1 [Homo sapiens]
          Length = 489

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V H  Q G+ HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 112 ASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAA-VKLADFG--LAIEVEGEQ- 167

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 168 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DLWACGVILYILLVGYPPFWDED- 217

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    SKR +A  A
Sbjct: 218 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA 265


>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
           sapiens]
          Length = 1551

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 50/171 (29%), Positives = 71/171 (41%), Gaps = 27/171 (15%)

Query: 336 PRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCL------ 389
           P LA   L +++  +  L Q G  HRD+K DN+L  LD +G   + +ADFG CL      
Sbjct: 169 PELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNVL--LDVNG--HIRLADFGSCLRLNTNG 224

Query: 390 -ADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFG 448
             D S+ +  P      D      L A E      GP       + D W++G  AYE+  
Sbjct: 225 MVDSSVAVGTP------DYISPEILQAMEEGKGHYGP-------QCDWWSLGVCAYELLF 271

Query: 449 LVNPFYGQGKAHLESR---SYQEAQLPALPESVPPDVRQLVRALLQREASK 496
              PFY +       +        Q P     VP   + L+R LL R+  +
Sbjct: 272 GETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQEER 322


>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
           isoform 4 [Homo sapiens]
          Length = 489

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
           isoform 5 [Homo sapiens]
          Length = 492

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
           isoform 2 [Homo sapiens]
          Length = 478

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
           isoform 3 [Homo sapiens]
          Length = 499

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H    GI HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAA-VKLADFG--LAIEVQGDQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ +  
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DMWACGVILYILLVGYPPFWDED- 218

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSARVA 503
              + R YQ+ +  A        ++V P+ + L+  +L    +KR +A  A
Sbjct: 219 ---QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA 266


>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
           isoform 3 [Homo sapiens]
          Length = 518

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H+ Q  I HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAA-VKLADFG--LAIEVQGEQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ + +
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DIWACGVILYILLVGYPPFWDEDQ 219

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSA 500
             L    YQ+ +  A        ++V P+ + L+  +L    +KR +A
Sbjct: 220 HKL----YQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263


>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
           isoform 4 [Homo sapiens]
          Length = 495

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H+ Q  I HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAA-VKLADFG--LAIEVQGEQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ + +
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DIWACGVILYILLVGYPPFWDEDQ 219

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSA 500
             L    YQ+ +  A        ++V P+ + L+  +L    +KR +A
Sbjct: 220 HKL----YQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263


>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
           isoform 6 [Homo sapiens]
          Length = 504

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H+ Q  I HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAA-VKLADFG--LAIEVQGEQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ + +
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DIWACGVILYILLVGYPPFWDEDQ 219

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSA 500
             L    YQ+ +  A        ++V P+ + L+  +L    +KR +A
Sbjct: 220 HKL----YQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263


>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
           isoform 1 [Homo sapiens]
          Length = 556

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H+ Q  I HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAA-VKLADFG--LAIEVQGEQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ + +
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DIWACGVILYILLVGYPPFWDEDQ 219

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSA 500
             L    YQ+ +  A        ++V P+ + L+  +L    +KR +A
Sbjct: 220 HKL----YQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263


>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
           isoform 2 [Homo sapiens]
          Length = 527

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A+  + Q+LE V+H+ Q  I HRDLK +N+L+     G   + +ADFG  LA E  G Q 
Sbjct: 113 ASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAA-VKLADFG--LAIEVQGEQ- 168

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGK 458
              +W+   G  G L +PEV    P  + V      D WA G I Y +     PF+ + +
Sbjct: 169 --QAWFGFAGTPGYL-SPEVLRKDPYGKPV------DIWACGVILYILLVGYPPFWDEDQ 219

Query: 459 AHLESRSYQEAQLPALP------ESVPPDVRQLVRALLQREASKRPSA 500
             L    YQ+ +  A        ++V P+ + L+  +L    +KR +A
Sbjct: 220 HKL----YQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITA 263


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
           sapiens]
          Length = 476

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 46/163 (28%), Positives = 81/163 (49%), Gaps = 21/163 (12%)

Query: 339 AAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQL 398
           A++++ Q+L  V +L + GI HRDLK +N+L  L P+    ++I DFG    +++ G+  
Sbjct: 120 ASLVIQQVLSAVKYLHENGIVHRDLKPENLLY-LTPEENSKIMITDFGLSKMEQN-GIMS 177

Query: 399 PFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKA-DAWAVGAIAYEIFGLVNPFYGQG 457
                     G    +APEV   +P       YSKA D W++G I Y +     PFY + 
Sbjct: 178 TAC-------GTPGYVAPEVLAQKP-------YSKAVDCWSIGVITYILLCGYPPFYEET 223

Query: 458 KAHLESR---SYQEAQLPALPESVPPDVRQLVRALLQREASKR 497
           ++ L  +    Y E + P   + +    +  +  LL+++ ++R
Sbjct: 224 ESKLFEKIKEGYYEFESP-FWDDISESAKDFICHLLEKDPNER 265


>gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo
            sapiens]
          Length = 1328

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 48/165 (29%), Positives = 69/165 (41%), Gaps = 27/165 (16%)

Query: 345  QLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWY 404
            Q+L+GV +L +  + HRD+K +N++  L P G   + + DFGC       GL    S   
Sbjct: 1169 QILQGVAYLHENCVVHRDIKGNNVM--LMPTGI--IKLIDFGCARRLAWAGLNGTHSDML 1224

Query: 405  VDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESR 464
                G    MAPEV       R      K+D W++G   +E+          GK  L S 
Sbjct: 1225 KSMHGTPYWMAPEVINESGYGR------KSDIWSIGCTVFEM--------ATGKPPLASM 1270

Query: 465  SYQEAQ---------LPALPESVPPDVRQLVRALLQREASKRPSA 500
                A          +P LP+    +    VR  L R+  +RPSA
Sbjct: 1271 DRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSA 1315


>gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo
           sapiens]
          Length = 510

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 48/165 (29%), Positives = 69/165 (41%), Gaps = 27/165 (16%)

Query: 345 QLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWY 404
           Q+L+GV +L +  + HRD+K +N++  L P G   + + DFGC       GL    S   
Sbjct: 351 QILQGVAYLHENCVVHRDIKGNNVM--LMPTGI--IKLIDFGCARRLAWAGLNGTHSDML 406

Query: 405 VDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESR 464
               G    MAPEV       R      K+D W++G   +E+          GK  L S 
Sbjct: 407 KSMHGTPYWMAPEVINESGYGR------KSDIWSIGCTVFEM--------ATGKPPLASM 452

Query: 465 SYQEAQ---------LPALPESVPPDVRQLVRALLQREASKRPSA 500
               A          +P LP+    +    VR  L R+  +RPSA
Sbjct: 453 DRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSA 497


>gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [Homo
           sapiens]
          Length = 431

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 52/177 (29%), Positives = 81/177 (45%), Gaps = 21/177 (11%)

Query: 325 LRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIAD 384
           L++  C   P  R  A    ++   + +L    I +RDLK +NIL  LD  G   +V+ D
Sbjct: 188 LQRERCFLEPRARFYAA---EIASALGYLHSLNIVYRDLKPENIL--LDSQG--HIVLTD 240

Query: 385 FGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAY 444
           FG C   E+I      S++     G    +APEV   +P  R V      D W +GA+ Y
Sbjct: 241 FGLC--KENIEHNSTTSTFC----GTPEYLAPEVLHKQPYDRTV------DWWCLGAVLY 288

Query: 445 EIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSAR 501
           E+   + PFY +  A +      +     L  ++    R L+  LLQ++ +KR  A+
Sbjct: 289 EMLYGLPPFYSRNTAEMYDNILNKPL--QLKPNITNSARHLLEGLLQKDRTKRLGAK 343


>gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4
           [Homo sapiens]
          Length = 445

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 52/177 (29%), Positives = 81/177 (45%), Gaps = 21/177 (11%)

Query: 325 LRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIAD 384
           L++  C   P  R  A    ++   + +L    I +RDLK +NIL  LD  G   +V+ D
Sbjct: 202 LQRERCFLEPRARFYAA---EIASALGYLHSLNIVYRDLKPENIL--LDSQG--HIVLTD 254

Query: 385 FGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAY 444
           FG C   E+I      S++     G    +APEV   +P  R V      D W +GA+ Y
Sbjct: 255 FGLC--KENIEHNSTTSTFC----GTPEYLAPEVLHKQPYDRTV------DWWCLGAVLY 302

Query: 445 EIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSAR 501
           E+   + PFY +  A +      +     L  ++    R L+  LLQ++ +KR  A+
Sbjct: 303 EMLYGLPPFYSRNTAEMYDNILNKPL--QLKPNITNSARHLLEGLLQKDRTKRLGAK 357


>gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3
           [Homo sapiens]
          Length = 459

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 52/177 (29%), Positives = 81/177 (45%), Gaps = 21/177 (11%)

Query: 325 LRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIAD 384
           L++  C   P  R  A    ++   + +L    I +RDLK +NIL  LD  G   +V+ D
Sbjct: 216 LQRERCFLEPRARFYAA---EIASALGYLHSLNIVYRDLKPENIL--LDSQG--HIVLTD 268

Query: 385 FGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAY 444
           FG C   E+I      S++     G    +APEV   +P  R V      D W +GA+ Y
Sbjct: 269 FGLC--KENIEHNSTTSTFC----GTPEYLAPEVLHKQPYDRTV------DWWCLGAVLY 316

Query: 445 EIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSAR 501
           E+   + PFY +  A +      +     L  ++    R L+  LLQ++ +KR  A+
Sbjct: 317 EMLYGLPPFYSRNTAEMYDNILNKPL--QLKPNITNSARHLLEGLLQKDRTKRLGAK 371


>gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2
           [Homo sapiens]
          Length = 526

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 52/177 (29%), Positives = 81/177 (45%), Gaps = 21/177 (11%)

Query: 325 LRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIAD 384
           L++  C   P  R  A    ++   + +L    I +RDLK +NIL  LD  G   +V+ D
Sbjct: 283 LQRERCFLEPRARFYAA---EIASALGYLHSLNIVYRDLKPENIL--LDSQG--HIVLTD 335

Query: 385 FGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAY 444
           FG C   E+I      S++     G    +APEV   +P  R V      D W +GA+ Y
Sbjct: 336 FGLC--KENIEHNSTTSTFC----GTPEYLAPEVLHKQPYDRTV------DWWCLGAVLY 383

Query: 445 EIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSAR 501
           E+   + PFY +  A +      +     L  ++    R L+  LLQ++ +KR  A+
Sbjct: 384 EMLYGLPPFYSRNTAEMYDNILNKPL--QLKPNITNSARHLLEGLLQKDRTKRLGAK 438


>gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Homo
           sapiens]
          Length = 740

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 51/158 (32%), Positives = 77/158 (48%), Gaps = 18/158 (11%)

Query: 343 LLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSS 402
           L +L   +DHL   GI +RDLK +NIL  LD +G   + + DFG  L+ ESI  +    S
Sbjct: 174 LAELALALDHLHSLGIIYRDLKPENIL--LDEEG--HIKLTDFG--LSKESIDHEKKAYS 227

Query: 403 WYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLE 462
           +     G    MAPEV   R   ++      AD W+ G + +E+     PF  QGK   E
Sbjct: 228 FC----GTVEYMAPEVVNRRGHTQS------ADWWSFGVLMFEMLTGTLPF--QGKDRKE 275

Query: 463 SRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSA 500
           + +        +P+ + P+ + L+R L +R  + R  A
Sbjct: 276 TMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGA 313



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 20/123 (16%)

Query: 335 SPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLV-IADFGCCLADES 393
           S R A+ +L  + + V++L  QG+ HRDLK  NIL  +D  G P  + I DFG       
Sbjct: 512 SEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY-VDESGNPESIRICDFG------- 563

Query: 394 IGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAV--IDYSKA-DAWAVGAIAYEIFGLV 450
              QL        R  NG LM P  +     P  +    Y  A D W++G + Y +    
Sbjct: 564 FAKQL--------RAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGY 615

Query: 451 NPF 453
            PF
Sbjct: 616 TPF 618


>gi|30039692 NIMA-related kinase 8 [Homo sapiens]
          Length = 692

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 65/250 (26%), Positives = 106/250 (42%), Gaps = 54/250 (21%)

Query: 292 LVDYPDVLPSRLHPEGLGHGRTLFLVMKNYPC-TLRQYL---CVNTPSPRLAAMMLLQLL 347
           L+++P+V+    + E     + L + M+  P  TL +++   C +           +Q+L
Sbjct: 57  LLNHPNVIE---YYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQIL 113

Query: 348 EGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDR 407
             + H+    I HRDLK+ NIL++        + I DFG       I   L   S     
Sbjct: 114 LALHHVHTHLILHRDLKTQNILLDKHR---MVVKIGDFG-------ISKILSSKSKAYTV 163

Query: 408 GGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQ 467
            G  C ++PE+   +P  +      K+D WA+G + YE+  L              R+++
Sbjct: 164 VGTPCYISPELCEGKPYNQ------KSDIWALGCVLYELASL-------------KRAFE 204

Query: 468 EAQLPAL------------PESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLWGEH 515
            A LPAL             +   P++RQLV +LL  E ++RP       + H+      
Sbjct: 205 AANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPP------LSHIMAQPLC 258

Query: 516 ILALKNLKLD 525
           I AL NL  D
Sbjct: 259 IRALLNLHTD 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,765,648
Number of Sequences: 37866
Number of extensions: 1249163
Number of successful extensions: 6016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 400
Number of HSP's that attempted gapping in prelim test: 5099
Number of HSP's gapped (non-prelim): 912
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.