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Search of human proteins with 9998948
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9998948 amiloride-sensitive cation channel 3 isoform c [Homo
sapiens]
(543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9998948 amiloride-sensitive cation channel 3 isoform c [Homo ... 1126 0.0
gi|9998946 amiloride-sensitive cation channel 3 isoform b [Homo ... 1014 0.0
gi|4757710 amiloride-sensitive cation channel 3 isoform a [Homo ... 1009 0.0
gi|9998944 amiloride-sensitive cation channel 1, neuronal isofor... 517 e-146
gi|21536349 amiloride-sensitive cation channel 2, neuronal isofo... 507 e-144
gi|21536351 amiloride-sensitive cation channel 2, neuronal isofo... 485 e-137
gi|34452695 amiloride-sensitive cation channel 1, neuronal isofo... 472 e-133
gi|33519442 amiloride-sensitive cation channel 4 isoform 1 [Homo... 443 e-124
gi|33519444 amiloride-sensitive cation channel 4 isoform 2 [Homo... 420 e-117
gi|31442761 amiloride-sensitive cation channel 5, intestinal [Ho... 224 1e-58
gi|227430289 sodium channel, nonvoltage-gated 1 alpha isoform 2 ... 132 8e-31
gi|227430287 sodium channel, nonvoltage-gated 1 alpha isoform 3 ... 132 8e-31
gi|4506815 sodium channel, nonvoltage-gated 1 alpha isoform 1 [H... 132 8e-31
gi|124301196 sodium channel, nonvoltage-gated 1, beta [Homo sapi... 123 5e-28
gi|42476333 sodium channel, nonvoltage-gated 1, gamma [Homo sapi... 107 2e-23
gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2 ... 102 9e-22
gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1... 102 9e-22
gi|39930351 dynamin binding protein [Homo sapiens] 36 0.079
gi|55741655 anoctamin 8 [Homo sapiens] 36 0.10
gi|161019170 mucin 5AC [Homo sapiens] 34 0.30
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 34 0.30
gi|239750721 PREDICTED: hypothetical protein, partial [Homo sapi... 34 0.39
gi|120952764 mastermind-like domain containing 1 [Homo sapiens] 33 0.87
gi|156105697 ring finger and CCCH-type zinc finger domains 2 iso... 32 1.1
gi|156105699 ring finger and CCCH-type zinc finger domains 2 iso... 32 1.1
gi|223633941 hypothetical protein LOC389730 [Homo sapiens] 32 1.5
gi|238859557 regulatory factor X1 [Homo sapiens] 32 1.5
gi|91206406 hypothetical protein LOC642265 [Homo sapiens] 32 1.5
gi|169174618 PREDICTED: family with sequence similarity 75, memb... 32 1.5
gi|239743732 PREDICTED: family with sequence similarity 75, memb... 32 1.5
>gi|9998948 amiloride-sensitive cation channel 3 isoform c [Homo
sapiens]
Length = 543
Score = 1126 bits (2913), Expect = 0.0
Identities = 543/543 (100%), Positives = 543/543 (100%)
Query: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV
Sbjct: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
Query: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA
Sbjct: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
Query: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF
Sbjct: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
Query: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ
Sbjct: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
Query: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG
Sbjct: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
Query: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR
Sbjct: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
Query: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY
Sbjct: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
Query: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR
Sbjct: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
Query: 481 HSSTNLTSHPSLCRHQDSLRLPPHLLPCHTALDLLSVSSEPRPDILDMPSLHVAFPSSPQ 540
HSSTNLTSHPSLCRHQDSLRLPPHLLPCHTALDLLSVSSEPRPDILDMPSLHVAFPSSPQ
Sbjct: 481 HSSTNLTSHPSLCRHQDSLRLPPHLLPCHTALDLLSVSSEPRPDILDMPSLHVAFPSSPQ 540
Query: 541 IKS 543
IKS
Sbjct: 541 IKS 543
>gi|9998946 amiloride-sensitive cation channel 3 isoform b [Homo
sapiens]
Length = 549
Score = 1014 bits (2621), Expect = 0.0
Identities = 504/548 (91%), Positives = 507/548 (92%), Gaps = 19/548 (3%)
Query: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV
Sbjct: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
Query: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA
Sbjct: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
Query: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF
Sbjct: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
Query: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ
Sbjct: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
Query: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG
Sbjct: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
Query: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR
Sbjct: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
Query: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY
Sbjct: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
Query: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR
Sbjct: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
Query: 481 HSSTNLT-----SHPSLCRH-----------QDSLRLP---PHLLPCHTALDLLSVSSEP 521
HSSTNL SH + H +D LP P L P TA LS SS P
Sbjct: 481 HSSTNLLQEGLGSHRTQVPHLSLGPSTLLCSEDLPPLPVPSPRLSPPPTAPATLSHSSRP 540
Query: 522 RPDILDMP 529
+L P
Sbjct: 541 AVCVLGAP 548
>gi|4757710 amiloride-sensitive cation channel 3 isoform a [Homo
sapiens]
Length = 531
Score = 1009 bits (2609), Expect = 0.0
Identities = 491/505 (97%), Positives = 493/505 (97%), Gaps = 4/505 (0%)
Query: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV
Sbjct: 1 MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQV 60
Query: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA
Sbjct: 61 AERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPA 120
Query: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF
Sbjct: 121 EHAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIF 180
Query: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ
Sbjct: 181 TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQ 240
Query: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG
Sbjct: 241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG 300
Query: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR
Sbjct: 301 SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR 360
Query: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY
Sbjct: 361 KDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNY 420
Query: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR
Sbjct: 421 ETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQR 480
Query: 481 HSSTNLTSHPSLCRHQDSLRLPPHL 505
HSSTNL L H+ + PHL
Sbjct: 481 HSSTNLLQE-GLGSHRTQV---PHL 501
>gi|9998944 amiloride-sensitive cation channel 1, neuronal isoform 2
[Homo sapiens]
Length = 512
Score = 517 bits (1331), Expect = e-146
Identities = 252/503 (50%), Positives = 340/503 (67%), Gaps = 27/503 (5%)
Query: 7 PEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRY 66
P E S I++FA+ ++HG+ H+F G L++RR +WA A V S+ L + +ERV Y
Sbjct: 7 PSEGSLQPSSIQIFANTSTLHGIRHIFVYGPLTIRRVLWAVAFVGSLGLLLVESSERVSY 66
Query: 67 YREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLD-----PAE 121
Y + H T +DE + L+FPAVTLCN+N R SRLT NDL+ AG L LD P
Sbjct: 67 YFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDP 126
Query: 122 HAA---FLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTT 178
H A L AL + + P F M + R GH L DM+L C+F+GQ CG ++FTT
Sbjct: 127 HLADPSVLEALRQKANFKHYKPKQ-FSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTT 185
Query: 179 IFTRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIR 238
+FT+ GKCY FNSG DG LLTT +GG GNGL+IMLD+QQ+EYLP+W + EET FE G++
Sbjct: 186 VFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVK 245
Query: 239 VQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDP 298
VQIHSQ EPP I +LG GV+PG+QTFV+ Q+Q+L++LPPPWG+C S+ + ++
Sbjct: 246 VQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDF------- 298
Query: 299 LGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAM 358
P Y++ CR+ CETRY+ C CRMV+MPGD P C+P+Q+K CA PA+ +
Sbjct: 299 --------FPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLL 350
Query: 359 LRKDS--CACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFE 416
KDS C C PC TRY KELSMV+IPS+ +A++L +K N+SE YI+EN+L LDIFFE
Sbjct: 351 AEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFE 410
Query: 417 ALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQ 476
ALNYET+EQKKAYE++ LLGDIGGQMGLFIGAS+LTILE+ DY+ E+ ++K+L +
Sbjct: 411 ALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEE 470
Query: 477 HSQRHSSTNLTSHPSLCRHQDSL 499
H N+++ ++ H +++
Sbjct: 471 DEGSHDE-NVSTCDTMPNHSETI 492
>gi|21536349 amiloride-sensitive cation channel 2, neuronal isoform
b [Homo sapiens]
Length = 528
Score = 507 bits (1306), Expect = e-144
Identities = 262/516 (50%), Positives = 342/516 (66%), Gaps = 35/516 (6%)
Query: 17 IRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTAL 76
I+ FAS+ ++HGL H+F LSL+R +WA + S+A L ERV+YY +HH T L
Sbjct: 18 IQAFASSSTLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQYYFHYHHVTKL 77
Query: 77 DERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLD-----PAEHAAF---LRA 128
DE + +L FPAVTLCN+N R S+++ NDL+ AG L L+ P A L
Sbjct: 78 DEVAASQLTFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEI 137
Query: 129 LGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYT 188
L F P P F+M + Y RAGH + DMLL C FRG+ C E+F +FTR GKCYT
Sbjct: 138 LQDKANFRSFKPKP-FNMREFYDRAGHDIRDMLLSCHFRGEVCSAEDFKVVFTRYGKCYT 196
Query: 189 FNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPP 248
FNSG DG L T +GG GNGL+IMLD+QQ+EYLPVW + +ET FE GI+VQIHSQ+EPP
Sbjct: 197 FNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPP 256
Query: 249 IIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSP 308
IDQLG GV+PG+QTFV+CQ+Q+L +LPPPWG C + +++ + + S
Sbjct: 257 FIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKAVTMDSDLDFFDS------------ 304
Query: 309 PYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLRKDS--CAC 366
Y++ CR+ CETRY+ C CRMV+MPGD P C+P+QYK CA PA+D ++ KD C C
Sbjct: 305 -YSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVEKDQEYCVC 363
Query: 367 PNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQK 426
PC TRY KELSMV+IPS+A+A++LA+K N+SE YI EN+L LDIFFE LNYET+EQK
Sbjct: 364 EMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQK 423
Query: 427 KAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQRHSSTN- 485
KAYE++ LLGDIGGQMGLFIGAS+LT+LE+ DY EV + K+ ++ ++R S+
Sbjct: 424 KAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKLCRRGKCQKEAKRSSADKG 483
Query: 486 -LTSHPSLCRHQ--DSLRLPP-------HLLPCHTA 511
S + RH +SLR P ++LP H A
Sbjct: 484 VALSLDDVKRHNPCESLRGHPAGMTYAANILPHHPA 519
>gi|21536351 amiloride-sensitive cation channel 2, neuronal isoform
a [Homo sapiens]
Length = 574
Score = 485 bits (1249), Expect = e-137
Identities = 262/562 (46%), Positives = 342/562 (60%), Gaps = 81/562 (14%)
Query: 17 IRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTAL 76
I+ FAS+ ++HGL H+F LSL+R +WA + S+A L ERV+YY +HH T L
Sbjct: 18 IQAFASSSTLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQYYFHYHHVTKL 77
Query: 77 DERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLD-----PAEHAAF---LRA 128
DE + +L FPAVTLCN+N R S+++ NDL+ AG L L+ P A L
Sbjct: 78 DEVAASQLTFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEI 137
Query: 129 LGRPPAPPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYT 188
L F P P F+M + Y RAGH + DMLL C FRG+ C E+F +FTR GKCYT
Sbjct: 138 LQDKANFRSFKPKP-FNMREFYDRAGHDIRDMLLSCHFRGEVCSAEDFKVVFTRYGKCYT 196
Query: 189 FNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPP 248
FNSG DG L T +GG GNGL+IMLD+QQ+EYLPVW + +ET FE GI+VQIHSQ+EPP
Sbjct: 197 FNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPP 256
Query: 249 IIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSP 308
IDQLG GV+PG+QTFV+CQ+Q+L +LPPPWG C + +++ + + S
Sbjct: 257 FIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKAVTMDSDLDFFDS------------ 304
Query: 309 PYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLRKDS--CAC 366
Y++ CR+ CETRY+ C CRMV+MPGD P C+P+QYK CA PA+D ++ KD C C
Sbjct: 305 -YSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVEKDQEYCVC 363
Query: 367 PNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQK 426
PC TRY KELSMV+IPS+A+A++LA+K N+SE YI EN+L LDIFFE LNYET+EQK
Sbjct: 364 EMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQK 423
Query: 427 KAYEMSEL----------------------------------------------LGDIGG 440
KAYE++ L LGDIGG
Sbjct: 424 KAYEIAGLLGELLMTPVPFSCHGHGVAPYHPKAGCSLLSHEGPPPQRPFPKPCCLGDIGG 483
Query: 441 QMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQRHSSTN--LTSHPSLCRHQ-- 496
QMGLFIGAS+LT+LE+ DY EV + K+ ++ ++R S+ S + RH
Sbjct: 484 QMGLFIGASILTVLELFDYAYEVIKHKLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPC 543
Query: 497 DSLRLPP-------HLLPCHTA 511
+SLR P ++LP H A
Sbjct: 544 ESLRGHPAGMTYAANILPHHPA 565
>gi|34452695 amiloride-sensitive cation channel 1, neuronal isoform
1 [Homo sapiens]
Length = 563
Score = 472 bits (1214), Expect = e-133
Identities = 242/514 (47%), Positives = 325/514 (63%), Gaps = 40/514 (7%)
Query: 6 GPEEARRPASDIRVFASNCSMHGLGHVFG----PGSLSLRRGMWAAAVVLSVATFLYQVA 61
GP ARR + S +HGL H+ G RR +W A S L +
Sbjct: 50 GPGVARRGRPSL----SRAKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSFGLLLSWSS 105
Query: 62 ERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAE 121
R+ Y+ F T + S +L FPAVT+CN NPLR RL+ DL++AG L L P
Sbjct: 106 NRLLYWLSFPSHTRVHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNR 165
Query: 122 HAA-FLRALGRPPAPPG-----------FMPSPTFD--MAQLYARAGHSLDDMLLDCRFR 167
A + L R P F+P F+ A R GH L+DMLL C++R
Sbjct: 166 TARPLVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYR 225
Query: 168 GQPCGPENFTTIFTRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRD 227
G+ CGP NF+++FT+ GKCY FNSG DG LLTT +GG GNGL+IMLD+QQ+EYLP+W +
Sbjct: 226 GELCGPHNFSSVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGE 285
Query: 228 NEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASL 287
EET FE G++VQIHSQ EPP I +LG GV+PG+QTFV+ Q+Q+L++LPPPWG+C S+ +
Sbjct: 286 TEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEM 345
Query: 288 NPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQY 347
++ P Y++ CR+ CETRY+ C CRMV+MPGD P C+P+Q+
Sbjct: 346 GLDF---------------FPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQH 390
Query: 348 KNCAHPAIDAMLRKDS--CACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIA 405
K CA PA+ + KDS C C PC TRY KELSMV+IPS+ +A++L +K N+SE YI+
Sbjct: 391 KECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYIS 450
Query: 406 ENVLALDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFR 465
EN+L LDIFFEALNYET+EQKKAYE++ LLGDIGGQMGLFIGAS+LTILE+ DY+ E+ +
Sbjct: 451 ENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIK 510
Query: 466 DKVLGYFWNRQHSQRHSSTNLTSHPSLCRHQDSL 499
+K+L + H N+++ ++ H +++
Sbjct: 511 EKLLDLLGKEEDEGSHDE-NVSTCDTMPNHSETI 543
>gi|33519442 amiloride-sensitive cation channel 4 isoform 1 [Homo
sapiens]
Length = 666
Score = 443 bits (1140), Expect = e-124
Identities = 237/472 (50%), Positives = 294/472 (62%), Gaps = 27/472 (5%)
Query: 16 DIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTA 75
D+ FAS ++HGLG GPG LRR +WA A++ S+A FLYQ A R Y H A
Sbjct: 168 DLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVA 227
Query: 76 LDERESHRLI-FPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPA 134
+D + FPAVTLCNIN R S L+ D+ + L GL P + A R P
Sbjct: 228 MDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLAN-LTGLPPKDRDGHRAAGLRYPE 286
Query: 135 PPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYTFNSGAD 194
P DM + R GH L DML C F G C NF+ ++TR GKCYTFN AD
Sbjct: 287 P---------DMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFN--AD 335
Query: 195 GAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLG 254
L + GGMG+GL+IMLD+QQEEYLP+WR+ ET FE GIRVQIHSQEEPP I QLG
Sbjct: 336 PRSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLG 395
Query: 255 LGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMG 314
GVSPG+QTFVSCQ+Q+L++LP PWG+C + S L P Y++
Sbjct: 396 FGVSPGFQTFVSCQEQRLTYLPQPWGNCRAES-----------ELREPELQGYSAYSVSA 444
Query: 315 CRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLR--KDSCACPNPCAS 372
CRL CE V ++C CRMV+MPG+ +C P Y CA +D++ + C CP PC
Sbjct: 445 CRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGPEGPCFCPTPCNL 504
Query: 373 TRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQKKAYEMS 432
TRY KE+SMVRIP+R +AR+LARK NR+E YI EN L LD+FFEAL E +EQ+ AY +S
Sbjct: 505 TRYGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLS 564
Query: 433 ELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQRHSST 484
LLGD+GGQMGLFIGAS+LT+LEILDY+ EV D+ L W R + +ST
Sbjct: 565 ALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDR-LKRVWRRPKTPLRTST 615
>gi|33519444 amiloride-sensitive cation channel 4 isoform 2 [Homo
sapiens]
Length = 647
Score = 420 bits (1079), Expect = e-117
Identities = 231/470 (49%), Positives = 284/470 (60%), Gaps = 42/470 (8%)
Query: 16 DIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTA 75
D+ FAS ++HGLG GPG LRR +WA A++ S+A FLYQ A R Y H A
Sbjct: 168 DLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVA 227
Query: 76 LDERESHRLI-FPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPA 134
+D + FPAVTLCNIN R S L+ D+ + L GL P + A R P
Sbjct: 228 MDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLAN-LTGLPPKDRDGHRAAGLRYPE 286
Query: 135 PPGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYTFNSGAD 194
P DM + R GH L DML C F G C NF+ ++TR GKCYTFN AD
Sbjct: 287 P---------DMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFN--AD 335
Query: 195 GAELLTTTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLG 254
L + GGMG+GL+IMLD+QQEEYLP+WR+ ET FE GIRVQIHSQEEPP I QLG
Sbjct: 336 PRSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLG 395
Query: 255 LGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMG 314
GVSPG+QTFVSCQ+Q+L++LP PWG+C + S L P Y++
Sbjct: 396 FGVSPGFQTFVSCQEQRLTYLPQPWGNCRAES-----------ELREPELQGYSAYSVSA 444
Query: 315 CRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDAMLRKDSCACPNPCASTR 374
CRL CE V ++C CRMV+MP + P+ C CP PC TR
Sbjct: 445 CRLRCEKEAVLQRCHCRMVHMPDSLGG-GPE----------------GPCFCPTPCNLTR 487
Query: 375 YAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQKKAYEMSEL 434
Y KE+SMVRIP+R +AR+LARK NR+E YI EN L LD+FFEAL E +EQ+ AY +S L
Sbjct: 488 YGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSAL 547
Query: 435 LGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVLGYFWNRQHSQRHSST 484
LGD+GGQMGLFIGAS+LT+LEILDY+ EV D+ L W R + +ST
Sbjct: 548 LGDLGGQMGLFIGASILTLLEILDYIYEVSWDR-LKRVWRRPKTPLRTST 596
>gi|31442761 amiloride-sensitive cation channel 5, intestinal [Homo
sapiens]
Length = 505
Score = 224 bits (572), Expect = 1e-58
Identities = 147/470 (31%), Positives = 232/470 (49%), Gaps = 39/470 (8%)
Query: 2 KPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVA 61
KP P E ++ D FA + S HG+ ++ S +RR +W V+ SV+ +Q+
Sbjct: 26 KPLPSPTERKKFDHD---FAISTSFHGIHNIVQNRS-KIRRVLWLVVVLGSVSLVTWQIY 81
Query: 62 ERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRLTPNDLHWAGSALLGLDPAE 121
R+ Y + T+++ + ++ FPAVT CN+N + + + + ++
Sbjct: 82 IRLLNYFTWPTTTSIEVQYVEKMEFPAVTFCNLNRFQTDAVAKFGVIFFLWHIVSKVLHL 141
Query: 122 HAAFLRALGRPPAPPGFMPSPTFDMAQLYARAGHSLDDM-LLDCRFRGQPCGPENFTTIF 180
+ G A F + + G L++ LLDC F G+PC P++F +F
Sbjct: 142 QEITANSTGSREATDFAASHQNFSIVEFIRNKGFYLNNSTLLDCEFFGKPCSPKDFAHVF 201
Query: 181 TRMGKCYTFNSGADGAELLTTTR--GGMGNGLDIMLDVQQEEYLPVWRDNEETPF-EVGI 237
T G C+TFN G E L R G GL ++ +V QE + DN F + GI
Sbjct: 202 TEYGNCFTFNHG----ETLQAKRKVSVSGRGLSLLFNVNQEAFT----DNPALGFVDAGI 253
Query: 238 RVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSD 297
IHS ++ P D LGL G V+ +Q + PWG+C NPN + +
Sbjct: 254 IFVIHSPKKVPQFDGLGLLSPVGMHARVTIRQVKTVHQEYPWGEC-----NPNIKLQNFS 308
Query: 298 PLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNCAHPAIDA 357
Y+ GC C+ +++ ++CGC +PG C Q+Y +C P +D
Sbjct: 309 S-----------YSTSGCLKECKAQHIKKQCGCVPFLLPGYGIECDLQKYFSCVSPVLDH 357
Query: 358 MLRKDSC-------ACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLA 410
+ KD C +CP C Y +S PS+ A ++L++KLN+S YI EN++
Sbjct: 358 IEFKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPSQKALKYLSKKLNQSRKYIRENLVK 417
Query: 411 LDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYL 460
++I + LNY+ +Q+KA +SELL D+GGQ+GLF GASL+TI+EI++YL
Sbjct: 418 IEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYL 467
>gi|227430289 sodium channel, nonvoltage-gated 1 alpha isoform 2
[Homo sapiens]
Length = 728
Score = 132 bits (332), Expect = 8e-31
Identities = 104/396 (26%), Positives = 178/396 (44%), Gaps = 46/396 (11%)
Query: 156 SLDDMLLDCRFRGQPCGPENFTTIFTRM-GKCYTFNSGADGAELLTTTRGGMGNGLDIML 214
+L + + CRF C N++ M G CYTFN + + L ++ G+ NGL +ML
Sbjct: 333 TLGNFIFACRFNQVSCNQANYSHFHHPMYGNCYTFND-KNNSNLWMSSMPGINNGLSLML 391
Query: 215 DVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSF 274
+Q +++P+ G RV +H Q+EP +D G + PG +T +S +++ L
Sbjct: 392 RAEQNDFIPLLST------VTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKETLDR 445
Query: 275 LPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVY 334
L +GDC+ + P+ + PS YT C +C + ++CGC ++
Sbjct: 446 LGGDYGDCTKNGSDV--------PVENLYPS---KYTQQVCIHSCFQESMIKECGCAYIF 494
Query: 335 --MPGDVPVCSPQQYKNCAHPAIDAMLRKDS------CACPNPCASTRYAKELSMVRIPS 386
P +V C +++ + + + S C PC+ T Y R PS
Sbjct: 495 YPRPQNVEYCDYRKHSSWGYCYYKLQVDFSSDHLGCFTKCRKPCSVTSYQLSAGYSRWPS 554
Query: 387 RAAARFLARKLNRSEAYIAEN----VLALDIFFEALNYETVEQKKAYEMSELLGDIGGQM 442
+ ++ + L+R Y N V ++IFF+ LNY+T + + M LL ++G Q
Sbjct: 555 VTSQEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYKTNSESPSVTMVTLLSNLGSQW 614
Query: 443 GLFIGASLLTILEILDYLCEV-----------FRDKVLGYFWNRQHSQRHSSTNLTSHPS 491
L+ G+S+L+++E+ + + ++ FR + + +Q +ST +S PS
Sbjct: 615 SLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSRYWSPGRGGRGAQEVASTLASSPPS 674
Query: 492 -LCRHQDSLRLP---PHLLPCHTALDLLSVSSEPRP 523
C H SL L P P TA + PRP
Sbjct: 675 HFCPHPMSLSLSQPGPAPSPALTAPPPAYATLGPRP 710
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 20 FASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTALD-E 78
F +N ++HG + ++ WA + + +Q Y F + +L+
Sbjct: 121 FCNNTTIHGAIRLVCSQHNRMKTAFWAVLWLCTFGMMYWQFGLLFGEY--FSYPVSLNIN 178
Query: 79 RESHRLIFPAVTLCNINPLR 98
S +L+FPAVT+C +NP R
Sbjct: 179 LNSDKLVFPAVTICTLNPYR 198
>gi|227430287 sodium channel, nonvoltage-gated 1 alpha isoform 3
[Homo sapiens]
Length = 692
Score = 132 bits (332), Expect = 8e-31
Identities = 104/396 (26%), Positives = 178/396 (44%), Gaps = 46/396 (11%)
Query: 156 SLDDMLLDCRFRGQPCGPENFTTIFTRM-GKCYTFNSGADGAELLTTTRGGMGNGLDIML 214
+L + + CRF C N++ M G CYTFN + + L ++ G+ NGL +ML
Sbjct: 297 TLGNFIFACRFNQVSCNQANYSHFHHPMYGNCYTFND-KNNSNLWMSSMPGINNGLSLML 355
Query: 215 DVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSF 274
+Q +++P+ G RV +H Q+EP +D G + PG +T +S +++ L
Sbjct: 356 RAEQNDFIPLLST------VTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKETLDR 409
Query: 275 LPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVY 334
L +GDC+ + P+ + PS YT C +C + ++CGC ++
Sbjct: 410 LGGDYGDCTKNGSDV--------PVENLYPS---KYTQQVCIHSCFQESMIKECGCAYIF 458
Query: 335 --MPGDVPVCSPQQYKNCAHPAIDAMLRKDS------CACPNPCASTRYAKELSMVRIPS 386
P +V C +++ + + + S C PC+ T Y R PS
Sbjct: 459 YPRPQNVEYCDYRKHSSWGYCYYKLQVDFSSDHLGCFTKCRKPCSVTSYQLSAGYSRWPS 518
Query: 387 RAAARFLARKLNRSEAYIAEN----VLALDIFFEALNYETVEQKKAYEMSELLGDIGGQM 442
+ ++ + L+R Y N V ++IFF+ LNY+T + + M LL ++G Q
Sbjct: 519 VTSQEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYKTNSESPSVTMVTLLSNLGSQW 578
Query: 443 GLFIGASLLTILEILDYLCEV-----------FRDKVLGYFWNRQHSQRHSSTNLTSHPS 491
L+ G+S+L+++E+ + + ++ FR + + +Q +ST +S PS
Sbjct: 579 SLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSRYWSPGRGGRGAQEVASTLASSPPS 638
Query: 492 -LCRHQDSLRLP---PHLLPCHTALDLLSVSSEPRP 523
C H SL L P P TA + PRP
Sbjct: 639 HFCPHPMSLSLSQPGPAPSPALTAPPPAYATLGPRP 674
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 20 FASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTALD-E 78
F +N ++HG + ++ WA + + +Q Y F + +L+
Sbjct: 85 FCNNTTIHGAIRLVCSQHNRMKTAFWAVLWLCTFGMMYWQFGLLFGEY--FSYPVSLNIN 142
Query: 79 RESHRLIFPAVTLCNINPLR 98
S +L+FPAVT+C +NP R
Sbjct: 143 LNSDKLVFPAVTICTLNPYR 162
>gi|4506815 sodium channel, nonvoltage-gated 1 alpha isoform 1 [Homo
sapiens]
Length = 669
Score = 132 bits (332), Expect = 8e-31
Identities = 104/396 (26%), Positives = 178/396 (44%), Gaps = 46/396 (11%)
Query: 156 SLDDMLLDCRFRGQPCGPENFTTIFTRM-GKCYTFNSGADGAELLTTTRGGMGNGLDIML 214
+L + + CRF C N++ M G CYTFN + + L ++ G+ NGL +ML
Sbjct: 274 TLGNFIFACRFNQVSCNQANYSHFHHPMYGNCYTFND-KNNSNLWMSSMPGINNGLSLML 332
Query: 215 DVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSF 274
+Q +++P+ G RV +H Q+EP +D G + PG +T +S +++ L
Sbjct: 333 RAEQNDFIPLLST------VTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKETLDR 386
Query: 275 LPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVY 334
L +GDC+ + P+ + PS YT C +C + ++CGC ++
Sbjct: 387 LGGDYGDCTKNGSDV--------PVENLYPS---KYTQQVCIHSCFQESMIKECGCAYIF 435
Query: 335 --MPGDVPVCSPQQYKNCAHPAIDAMLRKDS------CACPNPCASTRYAKELSMVRIPS 386
P +V C +++ + + + S C PC+ T Y R PS
Sbjct: 436 YPRPQNVEYCDYRKHSSWGYCYYKLQVDFSSDHLGCFTKCRKPCSVTSYQLSAGYSRWPS 495
Query: 387 RAAARFLARKLNRSEAYIAEN----VLALDIFFEALNYETVEQKKAYEMSELLGDIGGQM 442
+ ++ + L+R Y N V ++IFF+ LNY+T + + M LL ++G Q
Sbjct: 496 VTSQEWVFQMLSRQNNYTVNNKRNGVAKVNIFFKELNYKTNSESPSVTMVTLLSNLGSQW 555
Query: 443 GLFIGASLLTILEILDYLCEV-----------FRDKVLGYFWNRQHSQRHSSTNLTSHPS 491
L+ G+S+L+++E+ + + ++ FR + + +Q +ST +S PS
Sbjct: 556 SLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSRYWSPGRGGRGAQEVASTLASSPPS 615
Query: 492 -LCRHQDSLRLP---PHLLPCHTALDLLSVSSEPRP 523
C H SL L P P TA + PRP
Sbjct: 616 HFCPHPMSLSLSQPGPAPSPALTAPPPAYATLGPRP 651
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 20 FASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTALD-E 78
F +N ++HG + ++ WA + + +Q Y F + +L+
Sbjct: 62 FCNNTTIHGAIRLVCSQHNRMKTAFWAVLWLCTFGMMYWQFGLLFGEY--FSYPVSLNIN 119
Query: 79 RESHRLIFPAVTLCNINPLR 98
S +L+FPAVT+C +NP R
Sbjct: 120 LNSDKLVFPAVTICTLNPYR 139
>gi|124301196 sodium channel, nonvoltage-gated 1, beta [Homo
sapiens]
Length = 640
Score = 123 bits (308), Expect = 5e-28
Identities = 83/321 (25%), Positives = 148/321 (46%), Gaps = 33/321 (10%)
Query: 158 DDMLLDCRFRGQPCGPENFTTIF-TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDV 216
+ M+L C F +PC NFT+IF G CY FN G + L + G GL ++LD+
Sbjct: 243 EQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMT-EKALPSANPGTEFGLKLILDI 301
Query: 217 QQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLP 276
QE+Y+P G+R+ +H Q P I G+ G +T + +L +
Sbjct: 302 GQEDYVPFLAST------AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMG 355
Query: 277 PPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCR--MVY 334
P+ C+ + SD + Y++ C +C ++ R C C +
Sbjct: 356 EPYSPCTVNGSEVPVQNFYSDY--------NTTYSIQACLRSCFQDHMIRNCNCGHYLYP 407
Query: 335 MPGDVPVCSPQQYKNCAHPAIDAML---RKDSCA--CPNPCASTRYAKELSMVRIPSRAA 389
+P C+ + + + AH D + ++++C C C T+Y +SM PS A+
Sbjct: 408 LPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEAS 467
Query: 390 ARFLARKLNRSE------AYIAENVLALDIFFEALNYETVEQKKAYEMSELLGDIGGQMG 443
++ L++ + ++ L+I+F+ NY T+E+ A + LL ++GGQ G
Sbjct: 468 EDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFG 527
Query: 444 LFIGASLLTILE----ILDYL 460
++G S+L ++E I+D++
Sbjct: 528 FWMGGSVLCLIEFGEIIIDFV 548
Score = 33.5 bits (75), Expect = 0.51
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 20 FASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAERVRYYREFHHQTALDER 79
+ N + HG + G ++ MW +L A +Q +R Y + +L
Sbjct: 29 YCDNTNTHGPKRIICEGPK--KKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVG 86
Query: 80 ESHRLIFPAVTLCNINPLRRSRL 102
+ FPAVT+CN +P + S++
Sbjct: 87 FK-TMDFPAVTICNASPFKYSKI 108
>gi|42476333 sodium channel, nonvoltage-gated 1, gamma [Homo
sapiens]
Length = 649
Score = 107 bits (268), Expect = 2e-23
Identities = 82/328 (25%), Positives = 147/328 (44%), Gaps = 51/328 (15%)
Query: 155 HSLDDMLLDCRFRGQPCGPENFTTIFTRM-GKCYTFNSGADGAELLTTTRGGMGNGLDIM 213
+S +++L+ C F G C NFT M G CYTFN+ + +L+T+ GG GL ++
Sbjct: 251 YSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNN-RENETILSTSMGGSEYGLQVI 309
Query: 214 LDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLS 273
L + +EEY P + G +V IH Q+E P ++ +G + T + +
Sbjct: 310 LYINEEEYNPFLVSS------TGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESF 363
Query: 274 FLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPS---PPYTLMGCRLACETRYVARKCGC 330
L P+ C+ GS P + Y+L C +C + KCGC
Sbjct: 364 KLSEPYSQCTED--------------GSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGC 409
Query: 331 RMVY--MPGDVPVCSPQQYKN---CAHPAIDAMLRKD---SCACPNPCASTRYAKELSMV 382
+P C+ QQ+ N C + A ++++ C C+ + S+
Sbjct: 410 AQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLA 469
Query: 383 RIPSRAAARFLA------------RKLNRSEAYIAENVLALDIFFEALNYETVEQKKAYE 430
+ PS + ++L +KLN+++ + L IF++ LN ++ + A
Sbjct: 470 QWPSVVSEKWLLPVLTWDQGRQVNKKLNKTD------LAKLLIFYKDLNQRSIMESPANS 523
Query: 431 MSELLGDIGGQMGLFIGASLLTILEILD 458
+ LL + GGQ+GL++ S++ ++EI++
Sbjct: 524 IEMLLSNFGGQLGLWMSCSVVCVIEIIE 551
Score = 40.4 bits (93), Expect = 0.004
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 3 PTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVVLSVATFLYQVAE 62
P +GP+ A +R + N + HG + LRR +W + +VA L+Q A
Sbjct: 16 PVTGPQ-APTIKELMRWYCLNTNTHGCRRIVVSRG-RLRRLLWIGFTLTAVALILWQCAL 73
Query: 63 RVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRS 100
V F+ + + +L FPAVT+CNINP + S
Sbjct: 74 LVF---SFYTVSVSIKVHFRKLDFPAVTICNINPYKYS 108
>gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2
[Homo sapiens]
Length = 638
Score = 102 bits (254), Expect = 9e-22
Identities = 80/316 (25%), Positives = 138/316 (43%), Gaps = 37/316 (11%)
Query: 161 LLDCRFRGQPCGPENFTTIF-TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQE 219
+L C + G C F T G CYT DG + T R G+ +G+ ++L V+Q+
Sbjct: 260 VLSCSYDGLDCQARQFRTFHHPTYGSCYT----VDG--VWTAQRPGITHGVGLVLRVEQQ 313
Query: 220 EYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPW 279
+LP+ GIRV +H + P + V PG + +S ++ ++ L P+
Sbjct: 314 PHLPLLSTL------AGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPY 367
Query: 280 GDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVY--MPG 337
G C++ E + L + S YT C ++C + + C C +P
Sbjct: 368 GHCTAGG-----EGVEVELLHNTS------YTRQACLVSCFQQLMVETCSCGYYLHPLPA 416
Query: 338 DVPVCSPQQYKNCAHPAI----DAMLRKDSCA--CPNPCASTRYAKELSMVRIPSRAAAR 391
CS ++ H D + C CP PC + + R PS +A
Sbjct: 417 GAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAG 476
Query: 392 FLARKLNRS----EAYIAENVLA-LDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFI 446
+ L +++ + LA ++I ++ LNY +VE+ Y + +LL +G L+
Sbjct: 477 WTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWF 536
Query: 447 GASLLTILEILDYLCE 462
GAS+L++LE+L+ L +
Sbjct: 537 GASVLSLLELLELLLD 552
>gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1
[Homo sapiens]
Length = 704
Score = 102 bits (254), Expect = 9e-22
Identities = 80/316 (25%), Positives = 138/316 (43%), Gaps = 37/316 (11%)
Query: 161 LLDCRFRGQPCGPENFTTIF-TRMGKCYTFNSGADGAELLTTTRGGMGNGLDIMLDVQQE 219
+L C + G C F T G CYT DG + T R G+ +G+ ++L V+Q+
Sbjct: 326 VLSCSYDGLDCQARQFRTFHHPTYGSCYT----VDG--VWTAQRPGITHGVGLVLRVEQQ 379
Query: 220 EYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPW 279
+LP+ GIRV +H + P + V PG + +S ++ ++ L P+
Sbjct: 380 PHLPLLSTL------AGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPY 433
Query: 280 GDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVY--MPG 337
G C++ E + L + S YT C ++C + + C C +P
Sbjct: 434 GHCTAGG-----EGVEVELLHNTS------YTRQACLVSCFQQLMVETCSCGYYLHPLPA 482
Query: 338 DVPVCSPQQYKNCAHPAI----DAMLRKDSCA--CPNPCASTRYAKELSMVRIPSRAAAR 391
CS ++ H D + C CP PC + + R PS +A
Sbjct: 483 GAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAG 542
Query: 392 FLARKLNRS----EAYIAENVLA-LDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFI 446
+ L +++ + LA ++I ++ LNY +VE+ Y + +LL +G L+
Sbjct: 543 WTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWF 602
Query: 447 GASLLTILEILDYLCE 462
GAS+L++LE+L+ L +
Sbjct: 603 GASVLSLLELLELLLD 618
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 36.2 bits (82), Expect = 0.079
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 13/90 (14%)
Query: 266 SCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVA 325
SCQ+Q PPP +C +L+ + P S+ SPS PS P + R ++ VA
Sbjct: 1398 SCQKQPQDASPPP-KECDQGTLSASLNPSNSE--SSPSRCPSDPDSTSQPRSG-DSADVA 1453
Query: 326 RKCGCRMVYMPGDVPVCSPQQYKNCAHPAI 355
R P +P+ Y+N HP I
Sbjct: 1454 RDV---------KQPTATPRSYRNFRHPEI 1474
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 35.8 bits (81), Expect = 0.10
Identities = 20/38 (52%), Positives = 22/38 (57%), Gaps = 5/38 (13%)
Query: 276 PPPW-----GDCSSASLNPNYEPEPSDPLGSPSPSPSP 308
PPP GD S SL P P SDPL +P+PSPSP
Sbjct: 1181 PPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSP 1218
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 34.3 bits (77), Expect = 0.30
Identities = 19/69 (27%), Positives = 25/69 (36%)
Query: 282 CSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPV 341
C S++ +P P D G P P P + + A C C P +PV
Sbjct: 5774 CDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV 5833
Query: 342 CSPQQYKNC 350
C P Q C
Sbjct: 5834 CPPGQESIC 5842
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 34.3 bits (77), Expect = 0.30
Identities = 19/69 (27%), Positives = 25/69 (36%)
Query: 282 CSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPV 341
C S++ +P P D G P P P + + A C C P +PV
Sbjct: 5440 CDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV 5499
Query: 342 CSPQQYKNC 350
C P Q C
Sbjct: 5500 CPPGQESIC 5508
>gi|239750721 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 230
Score = 33.9 bits (76), Expect = 0.39
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 477 HSQRHSSTNLTSHPSLCRHQDSLRLPPHLLPCHTALDLLSVSSEPRPDILDMPSLHVAFP 536
H H S + + HP +C L + P L P A LSV P I PS+H++F
Sbjct: 168 HPSMHPSIHASIHPPICSSIFPLFIHPSLYPSIHASIHLSVHPSIHPSI--HPSIHLSFL 225
Query: 537 SSP 539
S P
Sbjct: 226 SYP 228
>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
Length = 774
Score = 32.7 bits (73), Expect = 0.87
Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 277 PPWGDCSSASLNPNYEPEPS-DPLGSPSPSPSPPYTLMGCRLAC 319
P W L+P Y P PS P P P P PP++ ++C
Sbjct: 326 PSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPFSPQSLMVSC 369
>gi|156105697 ring finger and CCCH-type zinc finger domains 2
isoform 1 [Homo sapiens]
Length = 1191
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 12/90 (13%)
Query: 230 ETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPP---PWGDCSSA- 285
+ PFEV Q PP + GV+P FV S LPP P+ D S
Sbjct: 605 QIPFEVPQYPQTGYYPPPPTVPA---GVAPCVPRFVRSNNVPESSLPPASMPYADHYSTF 661
Query: 286 ----SLNPN-YEPEPSDPLGSPSPSPSPPY 310
+N + Y+P P P G P PS Y
Sbjct: 662 SPRDRMNSSPYQPPPPQPYGPVPPVPSGMY 691
>gi|156105699 ring finger and CCCH-type zinc finger domains 2
isoform 2 [Homo sapiens]
Length = 1064
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 12/90 (13%)
Query: 230 ETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPP---PWGDCSSA- 285
+ PFEV Q PP + GV+P FV S LPP P+ D S
Sbjct: 605 QIPFEVPQYPQTGYYPPPPTVPA---GVAPCVPRFVRSNNVPESSLPPASMPYADHYSTF 661
Query: 286 ----SLNPN-YEPEPSDPLGSPSPSPSPPY 310
+N + Y+P P P G P PS Y
Sbjct: 662 SPRDRMNSSPYQPPPPQPYGPVPPVPSGMY 691
>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
Length = 1343
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)
Query: 230 ETPFEVGIRVQ---IHSQEEP-----PIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGD 281
+ P EVG R S EP PI+ L SP Q + Q L+ P P
Sbjct: 121 DPPGEVGERAPDGASQSSHEPMEDAAPILSPLA---SPDPQ---AKHPQDLASTPSPGPM 174
Query: 282 CSS-ASLNPNYEPEPSDPLGSPSPS-----PSPPYT 311
+S +SL+ + PEPS PL PSP P PP+T
Sbjct: 175 TTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHT 210
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 246 EPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPS 305
+PP P Y T + Q Q PP G + P P PS P G+P+PS
Sbjct: 39 QPPQPPTAAATPQPQYVTELQSPQPQAQ---PPGGQKQYVTELPAV-PAPSQPTGAPTPS 94
Query: 306 PSP 308
P+P
Sbjct: 95 PAP 97
>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
Length = 1347
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)
Query: 230 ETPFEVGIRVQ---IHSQEEP-----PIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGD 281
+ P EVG R S EP PI+ L SP Q + Q L+ P P
Sbjct: 121 DPPGEVGERAPDGASQSSHEPMEDAAPILSPLA---SPDPQ---AKHPQDLASTPSPGPM 174
Query: 282 CSS-ASLNPNYEPEPSDPLGSPSPS-----PSPPYT 311
+S +SL+ + PEPS PL PSP P PP+T
Sbjct: 175 TTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHT 210
>gi|169174618 PREDICTED: family with sequence similarity 75, member
A4 isoform 2 [Homo sapiens]
Length = 1272
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)
Query: 230 ETPFEVGIRVQ---IHSQEEP-----PIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGD 281
+ P EVG R S EP PI+ L SP Q + Q L+ P P
Sbjct: 46 DPPGEVGERAPDGASQSSHEPMEDAAPILSPLA---SPDPQ---AKHPQDLASTPSPGPM 99
Query: 282 CSS-ASLNPNYEPEPSDPLGSPSPS-----PSPPYT 311
+S +SL+ + PEPS PL PSP P PP+T
Sbjct: 100 TTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHT 135
>gi|239743732 PREDICTED: family with sequence similarity 75, member
A4 isoform 1 [Homo sapiens]
Length = 1361
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)
Query: 230 ETPFEVGIRVQ---IHSQEEP-----PIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGD 281
+ P EVG R S EP PI+ L SP Q + Q L+ P P
Sbjct: 135 DPPGEVGERAPDGASQSSHEPMEDAAPILSPLA---SPDPQ---AKHPQDLASTPSPGPM 188
Query: 282 CSS-ASLNPNYEPEPSDPLGSPSPS-----PSPPYT 311
+S +SL+ + PEPS PL PSP P PP+T
Sbjct: 189 TTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHT 224
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,682,056
Number of Sequences: 37866
Number of extensions: 1343365
Number of successful extensions: 6005
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 5806
Number of HSP's gapped (non-prelim): 213
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.