Search of human proteins with 9994187

Search of human proteins with 9994187

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9994187 platelet-derived growth factor C precursor [Homo
sapiens]
         (345 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9994187 platelet-derived growth factor C precursor [Homo sapi...   720   0.0  
gi|13376808 platelet derived growth factor D isoform 1 precursor...   280   1e-75
gi|15451921 platelet derived growth factor D isoform 2 precursor...   280   1e-75
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...    69   8e-12
gi|6912724 tolloid-like 2 [Homo sapiens]                               67   3e-11
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...    66   4e-11
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...    66   5e-11
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            65   1e-10
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]            65   1e-10
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]            65   1e-10
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]            65   1e-10
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]            65   1e-10
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]            65   1e-10
gi|126091152 cubilin [Homo sapiens]                                    64   3e-10
gi|66864913 neuropilin 1 isoform c [Homo sapiens]                      63   4e-10
gi|66912178 neuropilin 1 isoform b [Homo sapiens]                      63   4e-10
gi|182508169 neuropilin 1 isoform a [Homo sapiens]                     63   4e-10
gi|22547221 tolloid-like 1 [Homo sapiens]                              58   1e-08
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]       58   1e-08
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...    57   2e-08
gi|72384339 CUB domain containing protein 2 [Homo sapiens]             56   4e-08
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]       56   5e-08
gi|4758378 vascular endothelial growth factor D preproprotein [H...    54   2e-07
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H...    50   3e-06
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...    50   3e-06
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...    50   3e-06
gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho...    50   3e-06
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...    50   4e-06
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]           49   5e-06
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    49   7e-06

>gi|9994187 platelet-derived growth factor C precursor [Homo
           sapiens]
          Length = 345

 Score =  720 bits (1858), Expect = 0.0
 Identities = 345/345 (100%), Positives = 345/345 (100%)

Query: 1   MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHS 60
           MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHS
Sbjct: 1   MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHS 60

Query: 61  PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL 120
           PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL
Sbjct: 61  PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL 120

Query: 121 GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSA 180
           GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSA
Sbjct: 121 GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSA 180

Query: 181 LPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNL 240
           LPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNL
Sbjct: 181 LPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNL 240

Query: 241 LTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK 300
           LTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK
Sbjct: 241 LTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK 300

Query: 301 VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG 345
           VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
Sbjct: 301 VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG 345


>gi|13376808 platelet derived growth factor D isoform 1 precursor
           [Homo sapiens]
          Length = 370

 Score =  280 bits (717), Expect = 1e-75
 Identities = 148/318 (46%), Positives = 202/318 (63%), Gaps = 27/318 (8%)

Query: 45  QHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDIC 104
           + +  I V  NG + SPRFP++YPRN +L WRL + +EN  IQL FD +FGLE+ E+DIC
Sbjct: 51  RRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHS-QENTRIQLVFDNQFGLEEAENDIC 109

Query: 105 KYDFVEVEEPSDGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
           +YDFVEVE+ S+ +  I GRWCG   VP +  S+ NQI+I F SD+YF ++PGF I+Y++
Sbjct: 110 RYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 169

Query: 163 V------------MPQFTEAVS------PSVLPPSALPLDLLNNAITAFSTLEDLIRYLE 204
           +                T ++S      PSV  P+ +  D L+  I  F T+EDL++Y  
Sbjct: 170 LEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIA-DALDKKIAEFDTVEDLLKYFN 228

Query: 205 PERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLTEEVRLYSCTPRNFSVSIREELK 264
           PE WQ DLE++Y  T +  G+++   RKS+V DL+ L ++ + YSCTPRN+SV+IREELK
Sbjct: 229 PESWQEDLENMYLDTPRYRGRSY-HDRKSKV-DLDRLNDDAKRYSCTPRNYSVNIREELK 286

Query: 265 RTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRP---KTGVRGLH 321
             + +F+P CLLV+RCGGNC C   N   C C   K  KKYHEVLQ  P   K   R   
Sbjct: 287 LANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKT 346

Query: 322 KSLTDVALEHHEECDCVC 339
            +L D+ L+HHE CDC+C
Sbjct: 347 MALVDIQLDHHERCDCIC 364


>gi|15451921 platelet derived growth factor D isoform 2 precursor
           [Homo sapiens]
          Length = 364

 Score =  280 bits (717), Expect = 1e-75
 Identities = 148/318 (46%), Positives = 202/318 (63%), Gaps = 27/318 (8%)

Query: 45  QHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDIC 104
           + +  I V  NG + SPRFP++YPRN +L WRL + +EN  IQL FD +FGLE+ E+DIC
Sbjct: 45  RRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHS-QENTRIQLVFDNQFGLEEAENDIC 103

Query: 105 KYDFVEVEEPSDGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
           +YDFVEVE+ S+ +  I GRWCG   VP +  S+ NQI+I F SD+YF ++PGF I+Y++
Sbjct: 104 RYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSL 163

Query: 163 V------------MPQFTEAVS------PSVLPPSALPLDLLNNAITAFSTLEDLIRYLE 204
           +                T ++S      PSV  P+ +  D L+  I  F T+EDL++Y  
Sbjct: 164 LEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIA-DALDKKIAEFDTVEDLLKYFN 222

Query: 205 PERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLTEEVRLYSCTPRNFSVSIREELK 264
           PE WQ DLE++Y  T +  G+++   RKS+V DL+ L ++ + YSCTPRN+SV+IREELK
Sbjct: 223 PESWQEDLENMYLDTPRYRGRSY-HDRKSKV-DLDRLNDDAKRYSCTPRNYSVNIREELK 280

Query: 265 RTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRP---KTGVRGLH 321
             + +F+P CLLV+RCGGNC C   N   C C   K  KKYHEVLQ  P   K   R   
Sbjct: 281 LANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKT 340

Query: 322 KSLTDVALEHHEECDCVC 339
            +L D+ L+HHE CDC+C
Sbjct: 341 MALVDIQLDHHERCDCIC 358


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
           sapiens]
          Length = 730

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 50/134 (37%), Positives = 70/134 (52%), Gaps = 17/134 (12%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVA-VEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           NGSI SP +P  YP N   +W+LVA  +  + +Q  F E  G     +D+CKYDFVEV  
Sbjct: 599 NGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG-----NDVCKYDFVEVRS 653

Query: 114 --PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAV 171
              +D  + G++CGS   P    S+ N +R+ F SD    S+ GF  H+      F+E  
Sbjct: 654 GLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTV-SKKGFKAHF------FSEK- 704

Query: 172 SPSVLPPSALPLDL 185
            P++ PP   P  L
Sbjct: 705 RPALQPPRGRPHQL 718



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 8/107 (7%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
           G I SP +P  Y  + V +WR + V E   + LTF      E    D C YD++EV +  
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWR-IQVSEGFHVGLTFQ---SFEIERHDSCAYDYLEVRDGH 499

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
               T++GR+CG    P    S  +++ ++FVSD    ++ GF +++
Sbjct: 500 SESSTLIGRYCGY-EKPDDIKSTSSRLWLKFVSDGSI-NKAGFAVNF 544



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           + G+  SP +P+ Y  +   VWR+ V   E + +  T      L+     +C YD+VEV 
Sbjct: 329 STGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFT-----SLDLYRSRLCWYDYVEVR 383

Query: 113 EP--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIH 159
           +       + GR+CGS  +P   +S  +++ + F S   +  +  F ++
Sbjct: 384 DGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 47/108 (43%), Positives = 61/108 (56%), Gaps = 8/108 (7%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE- 113
           NG+I SP +P  YP N   VW++VA  +   I L F E F LE   +D+CKYDFVEV   
Sbjct: 628 NGTITSPGWPKEYPTNKNCVWQVVAPAQ-YRISLQF-EVFELEG--NDVCKYDFVEVRSG 683

Query: 114 -PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
              D  + GR+CGS T P    S+ N +R+ F SD    S+ GF  H+
Sbjct: 684 LSPDAKLHGRFCGSET-PEVITSQSNNMRVEFKSDNTV-SKRGFRAHF 729



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 7/97 (7%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           S  G++ SP +P  YP      W + +   +  ++LTF+E F +E  ++  C YD +E+ 
Sbjct: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGH-RVKLTFNE-FEIEQHQE--CAYDHLEMY 837

Query: 113 EPSD--GTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
           +  D    ILGR+CGS   P   ++ G+ + +RF SD
Sbjct: 838 DGPDSLAPILGRFCGS-KKPDPTVASGSSMFLRFYSD 873



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
           G I SP +P  Y  +   VWR + V E   + LTF      E    D C YD++EV +  
Sbjct: 473 GQIQSPNYPDDYRPSKECVWR-ITVSEGFHVGLTFQ---AFEIERHDSCAYDYLEVRDGP 528

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
             +  ++G +CG    P    S  N++ ++FVSD
Sbjct: 529 TEESALIGHFCGY-EKPEDVKSSSNRLWMKFVSD 561



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 36/105 (34%), Positives = 57/105 (54%), Gaps = 10/105 (9%)

Query: 59   HSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGT 118
            H+    + YP      W +VA E+   ++LTF   F +E+  D  C YD++E  +  D +
Sbjct: 905  HAQFGDNNYPSEARCDWVIVA-EDGYGVELTF-RTFEVEEEAD--CGYDYMEAYDGYDSS 960

Query: 119  I--LGRWCGSGTVPGKQI-SKGNQIRIRFVSDEYFPSEPGFCIHY 160
               LGR+CGSG  P ++I S G+ + IRF +D+   ++ GF   Y
Sbjct: 961  APRLGRFCGSG--PLEEIYSAGDSLMIRFRTDDTI-NKKGFHARY 1002



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 9/96 (9%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           T G+  +P FP+ YP  +  VWR+ V   E + +  T  + F     +  +C YD+VEV 
Sbjct: 358 TTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLF-----KSRLCWYDYVEVR 412

Query: 113 EP--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVS 146
           +       +LGR+CG   +P   +S  +++ + F S
Sbjct: 413 DGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRS 447


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
           sapiens]
          Length = 823

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 44/113 (38%), Positives = 62/113 (54%), Gaps = 10/113 (8%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVA-VEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           NGSI SP +P  YP N   +W+LVA  +  + +Q  F E  G     +D+CKYDFVEV  
Sbjct: 599 NGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG-----NDVCKYDFVEVRS 653

Query: 114 --PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVM 164
              +D  + G++CGS   P    S+ N +R+ F SD    S+ GF  H+  V+
Sbjct: 654 GLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTV-SKKGFKAHFFSVL 704



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 8/107 (7%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
           G I SP +P  Y  + V +WR + V E   + LTF      E    D C YD++EV +  
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWR-IQVSEGFHVGLTFQ---SFEIERHDSCAYDYLEVRDGH 499

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
               T++GR+CG    P    S  +++ ++FVSD    ++ GF +++
Sbjct: 500 SESSTLIGRYCGY-EKPDDIKSTSSRLWLKFVSDGSI-NKAGFAVNF 544



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           + G+  SP +P+ Y  +   VWR+ V   E + +  T      L+     +C YD+VEV 
Sbjct: 329 STGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFT-----SLDLYRSRLCWYDYVEVR 383

Query: 113 EP--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIH 159
           +       + GR+CGS  +P   +S  +++ + F S   +  +  F ++
Sbjct: 384 DGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 43/109 (39%), Positives = 60/109 (55%), Gaps = 10/109 (9%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVA-VEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           NGSI SP +P  YP N   +W+LVA  +  + +Q  F E  G     +D+CKYDFVEV  
Sbjct: 599 NGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG-----NDVCKYDFVEVRS 653

Query: 114 --PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
              +D  + G++CGS   P    S+ N +R+ F SD    S+ GF  H+
Sbjct: 654 GLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKSDNTV-SKKGFKAHF 700



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 8/107 (7%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
           G I SP +P  Y  + V +WR + V E   + LTF      E    D C YD++EV +  
Sbjct: 444 GHIQSPNYPDDYRPSKVCIWR-IQVSEGFHVGLTFQ---SFEIERHDSCAYDYLEVRDGH 499

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
               T++GR+CG    P    S  +++ ++FVSD    ++ GF +++
Sbjct: 500 SESSTLIGRYCGY-EKPDDIKSTSSRLWLKFVSDGSI-NKAGFAVNF 544



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 10/127 (7%)

Query: 23  ESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEE 82
           E    S F    NK         H+     ST+G+I SP +P  YP      W + +   
Sbjct: 726 ECQCRSGFVLHDNKHDCKEAGCDHK---VTSTSGTITSPNWPDKYPSKKECTWAISSTPG 782

Query: 83  NVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSD--GTILGRWCGSGTVPGKQISKGNQI 140
           +  ++LTF E      PE   C YD +EV +  D    +LGR+CGS   P   ++ G+++
Sbjct: 783 H-RVKLTFMEMDIESQPE---CAYDHLEVFDGRDAKAPVLGRFCGS-KKPEPVLATGSRM 837

Query: 141 RIRFVSD 147
            +RF SD
Sbjct: 838 FLRFYSD 844



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 8/104 (7%)

Query: 59  HSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGT 118
           H+    + YP      W +VA EE   ++L F + F +E+  D  C YD++E+ +  D T
Sbjct: 876 HAQFGDNNYPGGVDCEWVIVA-EEGYGVELVF-QTFEVEEETD--CGYDYMELFDGYDST 931

Query: 119 I--LGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
              LGR+CGSG  P +  S G+ + ++F SD+   ++ GF + Y
Sbjct: 932 APRLGRYCGSGP-PEEVYSAGDSVLVKFHSDDTI-TKKGFHLRY 973



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           + G+  SP +P+ Y  +   VWR+ V   E + +  T      L+     +C YD+VEV 
Sbjct: 329 STGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFT-----SLDLYRSRLCWYDYVEVR 383

Query: 113 EP--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIH 159
           +       + GR+CGS  +P   +S  +++ + F S   +  +  F ++
Sbjct: 384 DGFWRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
          Length = 901

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
          Length = 931

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
          Length = 555

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
          Length = 906

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
          Length = 926

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/133 (32%), Positives = 62/133 (46%), Gaps = 7/133 (5%)

Query: 32  FSSNKEQNGVQDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFD 91
           + S  +  G  DP     +     G I SP +P  YP +    W + A E N  I L F+
Sbjct: 14  YFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN 73

Query: 92  ERFGLEDPEDDICKYDFVEVE--EPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
             F +E  +   CKYDF+E+   +     +LG+ CG+   P   IS G+ + I+F SD Y
Sbjct: 74  PHFEIEKHD---CKYDFIEIRDGDSESADLLGKHCGN-IAPPTIISSGSMLYIKFTSD-Y 128

Query: 150 FPSEPGFCIHYNI 162
                GF + Y I
Sbjct: 129 ARQGAGFSLRYEI 141



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVE--ENVWIQLTFD-ERFGLEDPEDDICKYDFV 109
           S NG+I SP FP  YP N    + ++A    E +   L FD E   L+  E D CKYD++
Sbjct: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD-CKYDWL 213

Query: 110 EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQF 167
           ++ +  P  G ++G++CG+ T P +  S    + + F +D    ++ GF   Y +V  + 
Sbjct: 214 DIWDGIPHVGPLIGKYCGTKT-PSELRSSTGILSLTFHTD-MAVAKDGFSARYYLVHQEP 271

Query: 168 TEAVSPSVLPPSALPLDLLNNAITAFSTLED 198
            E    +V P       + N  I+A ST  D
Sbjct: 272 LENFQCNV-PLGMESGRIANEQISASSTYSD 301


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 20/158 (12%)

Query: 19   GTQAESNLSSKFQF-------SSNKEQNG------VQDPQHERIITVSTNGSIHSPRFPH 65
            GT   S ++S + F       SS+ E +G       +D     I+T ST G+I SP  P+
Sbjct: 892  GTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTEST-GTIQSPGHPN 950

Query: 66   TYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTILGRWCG 125
             YP      W ++ V+ N  I L F E F LE   +  C  D++EV +    T LGR+CG
Sbjct: 951  VYPHGINCTWHIL-VQPNHLIHLMF-ETFHLEFHYN--CTNDYLEVYDTDSETSLGRYCG 1006

Query: 126  SGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
              ++P    S GN + + FV+D     E GF I+Y  +
Sbjct: 1007 K-SIPPSLTSSGNSLMLVFVTDSDLAYE-GFLINYEAI 1042



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 39/109 (35%), Positives = 60/109 (55%), Gaps = 7/109 (6%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
            G + SP  PH YP +   +W L A  E   IQL F++RF +E   +  C  +++E+ +  
Sbjct: 2230 GYVTSPNHPHNYPPHADCIWILAAPPE-TRIQLQFEDRFDIEVTPN--CTSNYLELRDGV 2286

Query: 114  PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
             SD  IL ++CG+ ++P  Q S G  + +RF SD   P+  GF   Y+I
Sbjct: 2287 DSDAPILSKFCGT-SLPSSQWSSGEVMYLRFRSDN-SPTHVGFKAKYSI 2333



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 35/93 (37%), Positives = 52/93 (55%), Gaps = 5/93 (5%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-P 114
            G  +SP +P  YP N   VW +V+   N  +QL+F   F LED +D  C  DFVE+ E  
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGN-RLQLSFIS-FQLEDSQD--CSRDFVEIREGN 1802

Query: 115  SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
            + G ++GR+CG+          G+ + +RF+SD
Sbjct: 1803 ATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISD 1835



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 24   SNLSSKFQFSSNKEQNGVQDPQHERI---ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAV 80
            ++L  +FQ   +++  G +    +     I  S+  ++ SPRFP  YP N    W + A 
Sbjct: 1595 NSLFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQ 1654

Query: 81   EENVWIQLTFDERFGLEDPEDDICKYDFVEVEE--PSDGTILGRWCGSGTVPGKQISKGN 138
                 I L+F   F LE      C  DFVE+ +    D  + GR+CG+  +P    S  +
Sbjct: 1655 PPLNHITLSF-THFELE--RSTTCARDFVEILDGGHEDAPLRGRYCGT-DMPHPITSFSS 1710

Query: 139  QIRIRFVSD 147
             + +RFVSD
Sbjct: 1711 ALTLRFVSD 1719



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 9/121 (7%)

Query: 42  QDPQHERIITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPED 101
           Q P+   I+T    GSI SP +P  YP     VW +V    ++ +  TF     LE  +D
Sbjct: 586 QQPECGGILT-GPYGSIKSPGYPGNYPPGRDCVW-IVVTSPDLLVTFTFG-TLSLEHHDD 642

Query: 102 DICKYDFVEVEEPS--DGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIH 159
             C  D++E+ +       +LG++C + +VP  Q + G   RI F SD    S+ GF I 
Sbjct: 643 --CNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQ-TTGPFARIHFHSDSQI-SDQGFHIT 698

Query: 160 Y 160
           Y
Sbjct: 699 Y 699



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 55   NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
            +G IHSP +P  Y  NT   W ++ V+ N  + L F + F LE  +  I  YD +     
Sbjct: 1518 SGEIHSPNYPSPYRSNTDCSW-VIRVDRNHRVLLNFTD-FDLEPQDSCIMAYDGLS---- 1571

Query: 115  SDGTILGRWCGSGTVPGKQISKGNQIRIRFVS 146
            S  + L R CG   +    +S GN + +RF S
Sbjct: 1572 STMSRLARTCGREQLANPIVSSGNSLFLRFQS 1603



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 53   STNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV- 111
            S NG+I SP +P  +P N+   W  +   ++  ++++FD  F L    D  C+  FV+V 
Sbjct: 2811 SDNGTIRSPHWPQNFPENSRCSWTAI-THKSKHLEISFDNNF-LIPSGDGQCQNSFVKVW 2868

Query: 112  --EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDE 148
               E  D  +L   CG+   PG  I+  N     F S E
Sbjct: 2869 AGTEEVDKALLATGCGN-VAPGPVITPSNTFTAVFQSQE 2906



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 7/100 (7%)

Query: 67   YPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPED-DICKYDFVEVEE--PSDGTILGRW 123
            Y +N   VW ++A    V I LTF+  F LE       C YD+V++ +    +  + G +
Sbjct: 3179 YDKNLNCVWIIIAPVNKV-IHLTFNT-FALEAASTRQRCLYDYVKLYDGDSENANLAGTF 3236

Query: 124  CGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
            CGS TVP   IS GN + ++F+SD     E GF   Y I+
Sbjct: 3237 CGS-TVPAPFISSGNFLTVQFISDLTLERE-GFNATYTIM 3274



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 12/97 (12%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVA-VEENVWIQLTFDERFGLEDPEDDI----CKYDFVE 110
            GS  SP +P TYP NT   W LVA     V I   F     ++DP D +      YD   
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYF---ISIDDPGDCVQNYLTLYDGPN 3576

Query: 111  VEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
               PS G     +CG  T     ++  NQ+ I+F +D
Sbjct: 3577 ASSPSSGP----YCGGDTSIAPFVASSNQVFIKFHAD 3609



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 8/92 (8%)

Query: 57   SIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV-EEPS 115
            SI  P  P  Y  N    W L  +  + ++ ++F++ F L++     C+ DFVE+ +  +
Sbjct: 2349 SIGHPTLP--YRDNLFCEWHLQGLSGH-YLTISFED-FNLQNSSG--CEKDFVEIWDNHT 2402

Query: 116  DGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
             G ILGR+CG+ T+P    +  N   +RFV+D
Sbjct: 2403 SGNILGRYCGN-TIPDSIDTSSNTAVVRFVTD 2433



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 9/112 (8%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
            G I SP++P TYP N    W  V V+  + I + F++ F + + +    + D++ +    
Sbjct: 2101 GIITSPKYPETYPSNLNCSWH-VLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGP 2159

Query: 116  D--GTILGRWCGSGTVPGKQIS-----KGNQIRIRFVSDEYFPSEPGFCIHY 160
            D     LG   G+G   G   S       NQ+ ++F+SD     + GF I Y
Sbjct: 2160 DICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQ-GFKIKY 2210



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 11/128 (8%)

Query: 52   VSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV 111
            V T+G + SP +P  YP N+   W +     +V           ++  E   C YD + +
Sbjct: 1857 VGTHGKVASPFWPENYPHNSNYQWTVNVNASHV----VHGRILEMDIEEIQNCYYDKLRI 1912

Query: 112  -EEPS-DGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTE 169
             + PS    ++G +CG+ T      S GN +   F SD    S  GF + +  V     +
Sbjct: 1913 YDGPSIHARLIGAYCGTQTESFS--STGNSLTFHFYSDSSI-SGKGFLLEWFAV--DAPD 1967

Query: 170  AVSPSVLP 177
             V P++ P
Sbjct: 1968 GVLPTIAP 1975



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 7/108 (6%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP- 114
            G+  SP FP+ YP N   ++R + V     I + F   F LE+   +    DF+E+ +  
Sbjct: 1057 GTFTSPNFPNNYPNNWECIYR-ITVRTGQLIAVHF-TNFSLEEAIGNYYT-DFLEIRDGG 1113

Query: 115  -SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYN 161
                 +LG + GS  +P   IS  N++ ++F SD+   +  GF  +++
Sbjct: 1114 YEKSPLLGIFYGS-NLPPTIISHSNKLWLKFKSDQ-IDTRSGFSAYWD 1159



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
            GS  SP FP+ YP N   +W  +  +    IQLT  + F +E      C +D +E+    
Sbjct: 1400 GSFSSPGFPNRYPPNKECIW-YIRTDPGSSIQLTIHD-FDVE--YHSRCNFDVLEIYGGP 1455

Query: 116  D--GTILGRWC--GSGTVPGKQISKGNQIRIRFVSD 147
            D     + + C   S   P +  S GN++ IRF +D
Sbjct: 1456 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTD 1491



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 7/100 (7%)

Query: 50   ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
            I +  +G I SP +P+ Y   T     L A + +  I LTF + F +E      C +D V
Sbjct: 2692 IQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHT-ITLTFSD-FDIE--PHTTCAWDSV 2747

Query: 110  EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
             V      +  I+G++CG+   P    S  NQ+ + F SD
Sbjct: 2748 TVRNGGSPESPIIGQYCGNSN-PRTIQSGSNQLVVTFNSD 2786



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 7/97 (7%)

Query: 56   GSIHSPRFP--HTYPRNTVLVWRLVAVEE-NVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
            G+  SP +     Y RN    W L    + N  I + F++ F LE  +D  C++D +E  
Sbjct: 2580 GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFED-FYLESHQD--CQFDVLEFR 2636

Query: 113  E-PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDE 148
               +DG ++ R CG        +   +Q+ I FV++E
Sbjct: 2637 VGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNE 2673



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 6/94 (6%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-- 113
            G+  SP +P+  P   +  WR+ A  E   I L F+       P    C  + V V    
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITA-PEGRRITLMFNNLRLATHPS---CNNEHVIVFNGI 2516

Query: 114  PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
             S+   L + C S  V  +  S GN +++ F +D
Sbjct: 2517 RSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTD 2550



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/99 (22%), Positives = 51/99 (51%), Gaps = 8/99 (8%)

Query: 54   TNGSIHSPRFPHT-YPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
            ++G I SP + +  YP +   ++ +   ++ V I+L F +    +      C +D++ + 
Sbjct: 3044 SSGIITSPAYSYADYPNDMHCLYTITVSDDKV-IELKFSD---FDVVPSTSCSHDYLAIY 3099

Query: 113  EPSDGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSDEY 149
            + ++ +  +LG++CGS   P  + S  N + + F +D +
Sbjct: 3100 DGANTSDPLLGKFCGSKRPPNVK-SSNNSMLLVFKTDSF 3137



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 13/95 (13%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP FP+ YP      W +   +  V I L F      E      C+ D+VE+    
Sbjct: 825 GVIRSPFFPNVYPGERTCRWTIHQPQSQV-ILLNFTV---FEIGSSAHCETDYVEI---G 877

Query: 116 DGTILG-----RWCGSGTVPGKQISKGNQIRIRFV 145
             +ILG     ++CG+  +P    S  N + + FV
Sbjct: 878 SSSILGSPENKKYCGT-DIPSFITSVYNFLYVTFV 911



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 49   IITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDI-CKYD 107
            +I   T G + S  +P+ Y  N    W + A   N     T +  F   D E  I C  D
Sbjct: 1282 VIVNQTYGILESIGYPNPYSENQHCNWTIRATTGN-----TVNYTFLAFDLEHHINCSTD 1336

Query: 108  FVEVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGF 156
            ++E+ +      +GR+CG   +P    +  +++++  ++D     E GF
Sbjct: 1337 YLELYD--GPRQMGRYCGV-DLPPPGSTTSSKLQVLLLTDGVGRREKGF 1382


>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
          Length = 609

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 7/115 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           I + + G + SP +PH+Y  +    W + A +    I + F+  F LED +   CKYD+V
Sbjct: 31  IKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYDYV 87

Query: 110 EV--EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
           EV   E  +G   G++CG    P   +S G  + I+FVSD Y     GF I Y I
Sbjct: 88  EVFDGENENGHFRGKFCGK-IAPPPVVSSGPFLFIKFVSD-YETHGAGFSIRYEI 140



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLE----DPEDDICKYDFVE 110
           +G I SP FP  YP N++    +V   +   I L F E F LE     P    C+YD +E
Sbjct: 155 SGVIKSPGFPEKYP-NSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLE 212

Query: 111 VEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFT 168
           + +  P  G  +GR+CG  T PG+  S    + + F +D     E GF  +Y+++    +
Sbjct: 213 IWDGFPDVGPHIGRYCGQKT-PGRIRSSSGILSMVFYTDSAIAKE-GFSANYSVLQSSVS 270

Query: 169 E 169
           E
Sbjct: 271 E 271


>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
          Length = 644

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 7/115 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           I + + G + SP +PH+Y  +    W + A +    I + F+  F LED +   CKYD+V
Sbjct: 31  IKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYDYV 87

Query: 110 EV--EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
           EV   E  +G   G++CG    P   +S G  + I+FVSD Y     GF I Y I
Sbjct: 88  EVFDGENENGHFRGKFCGK-IAPPPVVSSGPFLFIKFVSD-YETHGAGFSIRYEI 140



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLE----DPEDDICKYDFVE 110
           +G I SP FP  YP N++    +V   +   I L F E F LE     P    C+YD +E
Sbjct: 155 SGVIKSPGFPEKYP-NSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLE 212

Query: 111 VEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFT 168
           + +  P  G  +GR+CG  T PG+  S    + + F +D     E GF  +Y+++    +
Sbjct: 213 IWDGFPDVGPHIGRYCGQKT-PGRIRSSSGILSMVFYTDSAIAKE-GFSANYSVLQSSVS 270

Query: 169 E 169
           E
Sbjct: 271 E 271


>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
          Length = 923

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 7/115 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           I + + G + SP +PH+Y  +    W + A +    I + F+  F LED +   CKYD+V
Sbjct: 31  IKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD---CKYDYV 87

Query: 110 EV--EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNI 162
           EV   E  +G   G++CG    P   +S G  + I+FVSD Y     GF I Y I
Sbjct: 88  EVFDGENENGHFRGKFCGK-IAPPPVVSSGPFLFIKFVSD-YETHGAGFSIRYEI 140



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 10/121 (8%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLE----DPEDDICKYDFVE 110
           +G I SP FP  YP N++    +V   +   I L F E F LE     P    C+YD +E
Sbjct: 155 SGVIKSPGFPEKYP-NSLECTYIVFAPKMSEIILEF-ESFDLEPDSNPPGGMFCRYDRLE 212

Query: 111 VEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFT 168
           + +  P  G  +GR+CG  T PG+  S    + + F +D     E GF  +Y+++    +
Sbjct: 213 IWDGFPDVGPHIGRYCGQKT-PGRIRSSSGILSMVFYTDSAIAKE-GFSANYSVLQSSVS 270

Query: 169 E 169
           E
Sbjct: 271 E 271


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 38/109 (34%), Positives = 61/109 (55%), Gaps = 10/109 (9%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVA-VEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           NG+I +P +P  YP N   VW++VA  +  + ++  F E  G     +++CKYD+VE+  
Sbjct: 626 NGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEG-----NEVCKYDYVEIWS 680

Query: 114 --PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
              S+  + G++CG+  VP    S+ N +RI F SD    S+ GF  H+
Sbjct: 681 GLSSESKLHGKFCGA-EVPEVITSQFNNMRIEFKSDNTV-SKKGFKAHF 727



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV- 111
           S +G I SP +P  YP      W + A   +  I+L F E F +E  ++  C YD +EV 
Sbjct: 780 SPSGLITSPNWPDKYPSRKECTWEISATPGH-RIKLAFSE-FEIEQHQE--CAYDHLEVF 835

Query: 112 -EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
             E     ILGR CG+  +P   ++ GN++ +RFVSD
Sbjct: 836 DGETEKSPILGRLCGN-KIPDPLVATGNKMFVRFVSD 871



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 40/133 (30%), Positives = 60/133 (45%), Gaps = 11/133 (8%)

Query: 20  TQAESNLSSKFQFSSNKEQNGVQDPQHERII---TVSTNGSIHSPRFPHTYPRNTVLVWR 76
           T  +S +  +F+ SSN    G     +E I         G I SP +P  Y      VW+
Sbjct: 433 TSTDSRMWIEFRSSSNWVGKGFA-AVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWK 491

Query: 77  LVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE--PSDGTILGRWCGSGTVPGKQI 134
            + V E+  + LTF      E    D C YD++EV +    +  ++GR+CG    P    
Sbjct: 492 -ITVSESYHVGLTFQ---SFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDK-PEDIR 546

Query: 135 SKGNQIRIRFVSD 147
           S  N + ++FVSD
Sbjct: 547 STSNTLWMKFVSD 559



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/107 (33%), Positives = 57/107 (53%), Gaps = 8/107 (7%)

Query: 59   HSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGT 118
            H+    + YP      W LV+ E    ++L+F + F +E+  D  C YD+VE+ +  D T
Sbjct: 903  HAQFGDNNYPGQVDCEWLLVS-ERGSRLELSF-QTFEVEEEAD--CGYDYVELFDGLDST 958

Query: 119  I--LGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
               LGR+CGSG  P +  S G+ + I F +D+   ++ GF I Y  +
Sbjct: 959  AVGLGRFCGSGP-PEEIYSIGDSVLIHFHTDDTI-NKKGFHIRYKSI 1003



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 8/112 (7%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           +NG++ SP FP+ YP  T  +WR V+V     I L F     ++  +  +C YD++EV +
Sbjct: 356 SNGNLSSPGFPNGYPSYTHCIWR-VSVTPGEKIVLNFTT---MDLYKSSLCWYDYIEVRD 411

Query: 114 P--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
                  +LGR+CG   +P    S  +++ I F S   +  + GF   Y  +
Sbjct: 412 GYWRKSPLLGRFCGD-KLPEVLTSTDSRMWIEFRSSSNWVGK-GFAAVYEAI 461


>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
          Length = 415

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 6/99 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           I    +G I S  FP  YP N+   W++   E  V + L F  RF ++   D++C+YDFV
Sbjct: 36  ILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKV-VVLNF--RF-IDLESDNLCRYDFV 91

Query: 110 EV-EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
           +V    ++G  +GR+CG+   PG  +S GN++ ++ +SD
Sbjct: 92  DVYNGHANGQRIGRFCGTFR-PGALVSSGNKMMVQMISD 129


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 34/106 (32%), Positives = 59/106 (55%), Gaps = 5/106 (4%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           +G + SP +P  YP+ +   +  +++EE   + L F E F +E   + +C YDF++++  
Sbjct: 193 SGELSSPEYPRPYPKLSSCTYS-ISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQ-- 249

Query: 115 SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
           +D    G +CG  T+P +  +K N + I FV+DE      G+ IHY
Sbjct: 250 TDREEHGPFCGK-TLPHRIETKSNTVTITFVTDE-SGDHTGWKIHY 293



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G + SP FP  Y  +    W L A      ++L F   F LE     +C+YDFV++   S
Sbjct: 28  GRLASPGFPGEYANDQERRWTLTA-PPGYRLRLYF-THFDLE--LSHLCEYDFVKLS--S 81

Query: 116 DGTILGRWCGSGT-----VPGKQ--ISKGNQIRIRFVSD 147
              +L   CG  +      PGK    S G+ + I F SD
Sbjct: 82  GAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD 120


>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
          Length = 449

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 40/109 (36%), Positives = 54/109 (49%), Gaps = 9/109 (8%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV--- 111
           +G+  SP FP  YP NT   W L+ V E   + LTF   F LE    D C +DF+E+   
Sbjct: 38  SGNFSSPNFPRLYPYNTECSW-LIVVAEGSSVLLTF-HAFDLE--YHDTCSFDFLEIYNG 93

Query: 112 EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
             P  G +LGR+CG    P    S  + + + F SD++  S  GF   Y
Sbjct: 94  ASPDKGNLLGRFCGK-VPPPPFTSSWHVMSVIFHSDKHVASH-GFSAGY 140



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 5/98 (5%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           +    +G + SP +P+ YP +    W ++       ++L F + F +E  E+  C YD+V
Sbjct: 148 VLTGLSGVLTSPEYPNNYPNSMECHW-VIRAAGPAHVKLVFVD-FQVEGNEE--CTYDYV 203

Query: 110 EVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
            V      T    +CGS T P   +S G+++++ F SD
Sbjct: 204 AVLGGPGPTRGHHYCGS-TRPPTLVSLGHELQVVFKSD 240



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 8/115 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPED--DICKYD 107
           + ++  G+  SP++P +YP N    W  + +     +++ F +   LE+P      C +D
Sbjct: 260 VYMAMRGNFSSPQYPSSYPNNIRCHW-TIRLPPGYQVKVFFLD-LDLEEPNSLTKTCDFD 317

Query: 108 FVEVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
            +   +    +  +LG WCG   +P    S  NQ+ +   +D    +  GF + Y
Sbjct: 318 HLAAFDGASEEAPLLGNWCGH-HLPPPVTSSHNQLLLLLHTDR-STTRRGFSVAY 370


>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
          Length = 449

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 48/142 (33%), Positives = 71/142 (50%), Gaps = 22/142 (15%)

Query: 56  GSIHSPRFPHT-YPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           G++ +P +P + YP      W ++A  + V I LTF E+F LE   D  C+YD V V   
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQV-IALTF-EKFDLEP--DTYCRYDSVSVFNG 223

Query: 115 S---DGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFT--- 168
           +   D   LG++CG   VPG   S+GN++ ++FVSD    ++ GF   Y   +P+ T   
Sbjct: 224 AVSDDSRRLGKFCGDA-VPGSISSEGNELLVQFVSDLSVTAD-GFSASYK-TLPRGTAKE 280

Query: 169 -------EAVSPSV-LPPSALP 182
                      P V LPP + P
Sbjct: 281 GQGPGPKRGTEPKVKLPPKSQP 302



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 7/96 (7%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           +G + S  FP+ YP N   +W  + V E   + L+F   F LE      C+YD +EV   
Sbjct: 45  SGYVASEGFPNLYPPNKECIW-TITVPEGQTVSLSF-RVFDLE--LHPACRYDALEVFAG 100

Query: 115 S--DGTILGRWCGSGTVPGKQISKGNQIRIRFVSDE 148
           S   G  LGR+CG+   P   ++ GNQ+ +R  +DE
Sbjct: 101 SGTSGQRLGRFCGTFR-PAPLVAPGNQVTLRMTTDE 135


>gi|4758378 vascular endothelial growth factor D preproprotein [Homo
           sapiens]
          Length = 354

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/193 (27%), Positives = 81/193 (41%), Gaps = 24/193 (12%)

Query: 161 NIVMPQFTEAVSPS------VLPPSALPLDLLNNAITAFSTLEDLIRYLEPERWQLDLED 214
           N+ M  + + V  S      V   S   L+     I A S+LE+L+R    E W+L    
Sbjct: 9   NVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSEDWKLWRCR 68

Query: 215 LYRPTWQLLGKAFVFGRKSR-------VVDLNLLTEEVRLYSCTPRNFSVSIREEL-KRT 266
           L   ++  +       R +R       +  L ++ EE +   C+PR   V +  EL K T
Sbjct: 69  LRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKST 128

Query: 267 DTIFWPGCLLVKRCGGNCACCLHNCNEC-QCVPSKVTKKYHEVLQLRPKTGVRGLHKSLT 325
           +T F P C+ V RCGG   CC      C     S ++K+  E+    P T V      L 
Sbjct: 129 NTFFKPPCVNVFRCGG---CCNEESLICMNTSTSYISKQLFEISV--PLTSV----PELV 179

Query: 326 DVALEHHEECDCV 338
            V + +H  C C+
Sbjct: 180 PVKVANHTGCKCL 192


>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
           sapiens]
          Length = 380

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 18/118 (15%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP +P +YP ++ + W  + V +   I+L F   F LE     +C+YD+V+VE  +
Sbjct: 29  GQIQSPGYPDSYPSDSEVTWN-ITVPDGFRIKLYF-MHFNLE--SSYLCEYDYVKVE--T 82

Query: 116 DGTILGRWCGSGT-----VPGKQI--SKGNQIRIRFVSDEYFPSE---PGFCIHYNIV 163
           +  +L  +CG  T      PG+++  S G+ + I F SD  F +E    GF  HY  V
Sbjct: 83  EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD--FSNEERFTGFDAHYMAV 138



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 4/92 (4%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP FP+ YP+++  ++  + +EE   + L F++ F +ED  +  C YD+++++   
Sbjct: 195 GVITSPDFPNPYPKSSECLYT-IELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIK--V 251

Query: 116 DGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
              +LG +CG    P    ++ + + I F SD
Sbjct: 252 GPKVLGPFCGE-KAPEPISTQSHSVLILFHSD 282


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 18/118 (15%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP +P +YP ++ + W  + V +   I+L F   F LE     +C+YD+V+VE  +
Sbjct: 29  GQIQSPGYPDSYPSDSEVTWN-ITVPDGFRIKLYF-MHFNLE--SSYLCEYDYVKVE--T 82

Query: 116 DGTILGRWCGSGT-----VPGKQI--SKGNQIRIRFVSDEYFPSE---PGFCIHYNIV 163
           +  +L  +CG  T      PG+++  S G+ + I F SD  F +E    GF  HY  V
Sbjct: 83  EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD--FSNEERFTGFDAHYMAV 138



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 4/92 (4%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP FP+ YP+++  ++  + +EE   + L F++ F +ED  +  C YD+++++   
Sbjct: 195 GVITSPDFPNPYPKSSECLYT-IELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIK--V 251

Query: 116 DGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
              +LG +CG    P    ++ + + I F SD
Sbjct: 252 GPKVLGPFCGE-KAPEPISTQSHSVLILFHSD 282


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 18/118 (15%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP +P +YP ++ + W  + V +   I+L F   F LE     +C+YD+V+VE  +
Sbjct: 29  GQIQSPGYPDSYPSDSEVTWN-ITVPDGFRIKLYF-MHFNLE--SSYLCEYDYVKVE--T 82

Query: 116 DGTILGRWCGSGT-----VPGKQI--SKGNQIRIRFVSDEYFPSE---PGFCIHYNIV 163
           +  +L  +CG  T      PG+++  S G+ + I F SD  F +E    GF  HY  V
Sbjct: 83  EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSD--FSNEERFTGFDAHYMAV 138



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/92 (29%), Positives = 51/92 (55%), Gaps = 4/92 (4%)

Query: 56  GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
           G I SP FP+ YP+++  ++  + +EE   + L F++ F +ED  +  C YD+++++   
Sbjct: 195 GVITSPDFPNPYPKSSECLYT-IELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIK--V 251

Query: 116 DGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
              +LG +CG    P    ++ + + I F SD
Sbjct: 252 GPKVLGPFCGE-KAPEPISTQSHSVLILFHSD 282


>gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo
           sapiens]
          Length = 525

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 8/122 (6%)

Query: 50  ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
           +  S  G   SP +P +YP N   ++ L A      I+LTFDE + +E   +  C++D +
Sbjct: 49  VRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQ-RIELTFDEHYYIEPSFE--CRFDHL 105

Query: 110 EVEEPSDG--TILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVM-PQ 166
           EV +   G   ++ R+CG  + P  + S G  + I+F SDE      GF   Y+ +  P 
Sbjct: 106 EVRDGPFGFSPLIDRYCGVKSPPLIR-STGRFMWIKFSSDEELEG-LGFRAKYSFIPDPD 163

Query: 167 FT 168
           FT
Sbjct: 164 FT 165


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 12/117 (10%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPED-DICKYDFVEVE 112
           +G++ S  +P TYP +TV  W + V + E V I      +FG  D ED D C ++++ + 
Sbjct: 81  SGTLTSINYPQTYPNSTVCEWEIRVKMGERVRI------KFGDFDIEDSDSCHFNYLRIY 134

Query: 113 E--PSDGTILGRWCGSGTVPGKQI-SKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQ 166
                  T +G++CG G      I SKGN+I + F+S  +  S  GF   Y+++  Q
Sbjct: 135 NGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHV-SGRGFLASYSVIDKQ 190


>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
          Length = 3565

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 9/114 (7%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           NG+I SP FPH YP      W ++  E N  IQL+F   F LE+  D +  YD     +P
Sbjct: 40  NGTIESPGFPHGYPNYANCTWIIITGERN-RIQLSF-HTFALEEDFDILSVYD----GQP 93

Query: 115 SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFT 168
             G +  R  G   +P   +S G+ + + F +D +  S  GF   Y  V+P  T
Sbjct: 94  QQGNLKVRLSGF-QLPSSIVSTGSILTLWFTTD-FAVSAQGFKALYE-VLPSHT 144



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 12/110 (10%)

Query: 53  STNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVE 112
           +++G I SP +P  Y  N   VW L+  E    I L F++ F +E       ++DF+ V+
Sbjct: 591 ASSGIILSPNYPEEYGNNMNCVW-LIISEPGSRIHLIFND-FDVEP------QFDFLAVK 642

Query: 113 EP--SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
           +   SD T+LG + G+  VP +  S G+ +R+ F SD +  +  GF I Y
Sbjct: 643 DDGISDITVLGTFSGN-EVPSQLASSGHIVRLEFQSD-HSTTGRGFNITY 690



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           T+ SI SP FP  Y  N    W ++A E    I L F + F LE+       YDF+E+  
Sbjct: 215 TSSSISSPHFPSEYENNADCTWTILA-EPGDTIALVFTD-FQLEE------GYDFLEISG 266

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
               +I   W     +P   IS  N +R+ F SD
Sbjct: 267 TEAPSI---WLTGMNLPSPVISSKNWLRLHFTSD 297



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 10/109 (9%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVE-ENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
            G+I SP +P  Y  N   +W+++  E   + IQ+     F  E   D +  +D  +V  P
Sbjct: 1812 GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVI---SFATEQNWDSLEIHDGGDVTAP 1868

Query: 115  SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
              G+  G      TVP    S  NQ+ + F SD    +  GF + Y  V
Sbjct: 1869 RLGSFSGT-----TVPALLNSTSNQLYLHFQSD-ISVAAAGFHLEYKTV 1911



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           +G I SP +P  Y  N   VW +   + +  I+L F+E F LE   D +   D  +V + 
Sbjct: 420 SGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEE-FELERGYDTLTVGDAGKVGDT 478

Query: 115 SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGF 156
              ++L    GS +VP   +S  NQ+ +   SD+   S PGF
Sbjct: 479 R--SVLYVLTGS-SVPDLIVSMSNQMWLHLQSDDSIGS-PGF 516



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 56   GSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPS 115
            G I SP +P  YP      WR V V  +  I L F + F +E        YDF+ + E  
Sbjct: 1461 GVILSPNYPQPYPPGKECDWR-VKVNPDFVIALIF-KSFNMEP------SYDFLHIYEGE 1512

Query: 116  DGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
            D    ++G + GS   P +  S GN + + F SD
Sbjct: 1513 DSNSPLIGSYQGS-QAPERIESSGNSLFLAFRSD 1545



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 53   STNGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEV 111
            S NG+I+SP FP  YP     +W + V     V+I  T       E   D I  +D  + 
Sbjct: 2153 SQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTL---LQTEAVNDYIAVWDGPDQ 2209

Query: 112  EEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
              P  G   G      T      S  NQ+ ++F SD
Sbjct: 2210 NSPQLGVFSG-----NTALETAYSSTNQVLLKFHSD 2240



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 15/114 (13%)

Query: 51   TVST-NGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDF 108
            T+ST  G I SP FP +YP N    WR+ + +     IQ      F  E        +DF
Sbjct: 1978 TLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFL---NFSTE------ANHDF 2028

Query: 109  VEVEEPSDGT--ILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
            +E++     T  ++G++ G+  +P   +S  ++  I F SD +  +  GF + Y
Sbjct: 2029 LEIQNGPYHTSPMIGQFSGT-DLPAALLSTTHETLIHFYSD-HSQNRQGFKLAY 2080


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
           sapiens]
          Length = 3667

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 11/94 (11%)

Query: 54  TNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
           ++G I SP FP+ Y  N    W +VA E    I L F + F +E+      KYD++E+E 
Sbjct: 208 SSGIISSPSFPNEYHNNADCTWTIVA-EPGDTISLIFTD-FQMEE------KYDYLEIEG 259

Query: 114 PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSD 147
               TI   W     +P   IS  N +R+ FV+D
Sbjct: 260 SEPPTI---WLSGMNIPPPIISNKNWLRLHFVTD 290



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 5/106 (4%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           +G+  SP FP  Y  N   VW + AV  N  IQ+ F+E F LE   D +   D  EV +P
Sbjct: 516 SGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEE-FDLEIGYDTLTIGDGGEVGDP 574

Query: 115 SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
              T+L    GS  VP   +S  +Q+ +   +DE   S  GF ++Y
Sbjct: 575 R--TVLQVLTGS-FVPDLIVSMSSQMWLHLQTDESVGS-VGFKVNY 616



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 10/127 (7%)

Query: 55  NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
           NG+I SP FP+ YP      W ++A E N  IQ+ F + F LE+  D +  YD      P
Sbjct: 33  NGTIESPGFPYGYPNGANCTWVIIAEERN-RIQIVF-QSFALEEEYDYLSLYD----GHP 86

Query: 115 SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPS 174
                  R  G   +P    S  +   +R  SD +  S  GF ++Y  +  Q +   +P 
Sbjct: 87  HPTNFRTRLTGF-HLPPPVTSTKSVFSLRLTSD-FAVSAHGFKVYYEEL--QSSSCGNPG 142

Query: 175 VLPPSAL 181
           V P   L
Sbjct: 143 VPPKGVL 149



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 8/114 (7%)

Query: 50   ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
            I     G+I SP +P  Y  N   VW+ + V E   IQ+     F  E   D +  YD  
Sbjct: 1902 ILTKRKGTILSPGYPEPYDNNLNCVWK-ITVPEGAGIQVQV-VSFATEHNWDSLDFYDGG 1959

Query: 110  EVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIV 163
            +   P     LG + G+ T+P    S  N + + F SD    S  GF + Y  +
Sbjct: 1960 DNNAPR----LGSYSGT-TIPHLLNSTSNNLYLNFQSD-ISVSAAGFHLEYTAI 2007



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 54   TNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
            ++G I SP FPH YP +    W  + V  +  I L F   F +E   D +  YD  +   
Sbjct: 1555 SSGFILSPNFPHPYPHSRDCDW-TITVNADYVISLAFIS-FSIEPNYDFLYIYDGPDSNS 1612

Query: 114  PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
            P  G+          +P +  S  N + + F SD    S  GF + Y
Sbjct: 1613 PLIGSF-----QDSKLPERIESSSNTMHLAFRSDGSV-SYTGFHLEY 1653



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 17/148 (11%)

Query: 55   NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
            NG+I+SP +P  YP      W LV V     I + F      E   D I  +D  +   P
Sbjct: 2251 NGTIYSPGYPDEYPNFQDCFW-LVRVPPGNGIYINFTV-LQTEPIYDFITVWDGPDQNSP 2308

Query: 115  SDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPS 174
              G   G      T      S  NQI I+F SD  F +   F + Y+    +  +     
Sbjct: 2309 QIGQFSG-----NTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLRVCQ----- 2356

Query: 175  VLPPSALPLDLLNNAITAFSTLEDLIRY 202
              PP  +P   +      F  + D+IRY
Sbjct: 2357 --PPPPVPNAEILTEDDEFE-IGDIIRY 2381



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 7/111 (6%)

Query: 50   ITVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFV 109
            + + + G I SP +P +YP   +  W  ++VE+   I + F E F  E   D +  YD  
Sbjct: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWS-ISVEKGYNITM-FVEFFQTEKEFDVLQVYDGP 2478

Query: 110  EVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
             ++ P   ++ G +  +  +     S G+++ +++ +D +  ++ GF I Y
Sbjct: 2479 NIQSPVLISLSGDYSSAFNI----TSNGHEVFLQWSAD-HGNNKKGFRIRY 2524



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 14/109 (12%)

Query: 55   NGSIHSPRFPHTYPRNTVLVWRL-VAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE 113
            +G I SP FP  YP +    W + + +   V +Q      F  E        +D++EV  
Sbjct: 2079 SGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFV---NFSTE------TIHDYLEVRS 2129

Query: 114  PSD--GTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHY 160
             S    T++GR  G   +P    S  ++  + F SD Y  ++ GF I Y
Sbjct: 2130 GSSETSTVIGRLSGP-QIPSSLFSTTHETSLYFHSD-YSQNKQGFHIVY 2176



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 10/109 (9%)

Query: 55   NGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEP 114
            +G+I SP +P  YP +    W  V V     +Q  F   F LED  D +   +     +P
Sbjct: 1035 SGTILSPGYPEFYPNSLNCTW-TVDVTHGKGVQFNF-HTFHLEDHHDYLLITENGSFTQP 1092

Query: 115  SDGTILGRWCGSGTVPGKQIS-KGN-QIRIRFVSDEYFPSEPGFCIHYN 161
                 L R  GS   P       GN + ++RF+SD +  S  GF I ++
Sbjct: 1093 -----LARLTGSDLPPTINAGLYGNFRAQLRFISD-FSISYEGFNITFS 1135



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 51   TVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWI-QLTFDERFGLEDPEDDICKYDFV 109
            +  + G++ SP +P  Y      V+ +   +E V   Q  F +             +D V
Sbjct: 1726 STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQT----------SLHDVV 1775

Query: 110  EVEE--PSDGTILGRWCGSGTVPGKQISKGNQIRIRFVS 146
            EV +      ++L    GS +     +S GNQI IRF S
Sbjct: 1776 EVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTS 1814


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,506,723
Number of Sequences: 37866
Number of extensions: 690764
Number of successful extensions: 1809
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 1611
Number of HSP's gapped (non-prelim): 209
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.